Bulathsinhalage G. Perera, Ph.D. - Publications

Affiliations: 
2012 Chemistry University of Washington, Seattle, Seattle, WA 
Area:
Chemical Biology of Signal Transduction

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, et al. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. Cell. 158: 534-48. PMID 25018104 DOI: 10.1016/J.Cell.2014.07.002  0.747
2013 Hari SB, Perera BG, Ranjitkar P, Seeliger MA, Maly DJ. Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src. Acs Chemical Biology. 8: 2734-43. PMID 24106839 DOI: 10.1021/Cb400663K  0.793
2013 Andrews SS, Hill ZB, Perera BG, Maly DJ. Label transfer reagents to probe p38 MAPK binding partners. Chembiochem : a European Journal of Chemical Biology. 14: 209-16. PMID 23319368 DOI: 10.1002/Cbic.201200673  0.757
2013 Brigham JL, Perera BG, Maly DJ. A hexylchloride-based catch-and-release system for chemical proteomic applications. Acs Chemical Biology. 8: 691-9. PMID 23305300 DOI: 10.1021/Cb300623A  0.66
2012 Ranjitkar P, Perera BG, Swaney DL, Swaney DL, Hari SB, Larson ET, Krishnamurty R, Merritt EA, Villén J, Maly DJ. Affinity-based probes based on type II kinase inhibitors. Journal of the American Chemical Society. 134: 19017-25. PMID 23088519 DOI: 10.1021/Ja306035V  0.723
2012 Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, Schürer SC, Oakes SA, Papa FR, Maly DJ. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nature Chemical Biology. 8: 982-9. PMID 23086298 DOI: 10.1038/Nchembio.1094  0.819
2012 Larson ET, Ojo KK, Murphy RC, Johnson SM, Zhang Z, Kim JE, Leibly DJ, Fox AM, Reid MC, Dale EJ, Perera BG, Kim J, Hewitt SN, Hol WG, Verlinde CL, et al. Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. Journal of Medicinal Chemistry. 55: 2803-10. PMID 22369268 DOI: 10.1021/Jm201725V  0.749
2012 Johnson SM, Murphy RC, Geiger JA, DeRocher AE, Zhang Z, Ojo KK, Larson ET, Perera BG, Dale EJ, He P, Reid MC, Fox AM, Mueller NR, Merritt EA, Fan E, et al. Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity. Journal of Medicinal Chemistry. 55: 2416-26. PMID 22320388 DOI: 10.1021/Jm201713H  0.704
2012 Hill ZB, Perera BG, Andrews SS, Maly DJ. Targeting diverse signaling interaction sites allows the rapid generation of bivalent kinase inhibitors. Acs Chemical Biology. 7: 487-95. PMID 22148755 DOI: 10.1021/Cb200387G  0.824
2011 Hill ZB, Perera BG, Maly DJ. Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity. Molecular Biosystems. 7: 447-56. PMID 21060940 DOI: 10.1039/C0Mb00108B  0.829
2010 Murphy RC, Ojo KK, Larson ET, Castellanos-Gonzalez A, Perera BG, Keyloun KR, Kim JE, Bhandari JG, Muller NR, Verlinde CL, White AC, Merritt EA, Van Voorhis WC, Maly DJ. Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. Acs Medicinal Chemistry Letters. 1: 331-335. PMID 21116453 DOI: 10.1021/Ml100096T  0.688
2009 Hill ZB, Perera BG, Maly DJ. A chemical genetic method for generating bivalent inhibitors of protein kinases. Journal of the American Chemical Society. 131: 6686-8. PMID 19391594 DOI: 10.1021/Ja900871Y  0.835
2008 Perera BG, Maly DJ. Design, synthesis and characterization of "clickable" 4-anilinoquinazoline kinase inhibitors. Molecular Biosystems. 4: 542-50. PMID 18493651 DOI: 10.1039/B720014E  0.78
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