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Beiyan Zou, Ph.D. - Publications

Affiliations: 
2007 Pennsylvania State University, State College, PA, United States 
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li M, Wu Y, Zou B, Wang X, Li M, Yu H. Identification of WB4101, an alpha1-adrenoceptor antagonist, as a sodium channel blocker. Molecular Pharmacology. PMID 29884692 DOI: 10.1124/mol.117.111252  0.329
2017 Wu Y, Zou B, Liang L, Li M, Tao YX, Yu H, Wang X, Li M. Loperamide inhibits sodium channels to alleviate inflammatory hyperalgesia. Neuropharmacology. PMID 28216001 DOI: 10.1016/J.Neuropharm.2017.02.010  0.384
2016 Yu HB, Zou BY, Wang XL, Li M. Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay. Acta Pharmacologica Sinica. 37: 111-23. PMID 26725739 DOI: 10.1038/aps.2015.143  0.301
2015 Zou B. Ion channel profiling to advance drug discovery and development. Drug Discovery Today. Technologies. 18: 18-23. PMID 26723888 DOI: 10.1016/J.Ddtec.2015.10.003  0.386
2015 Yu H, Zou B, Wang X, Li M. Effect of tyrphostin AG879 on Kv 4.2 and Kv 4.3 potassium channels. British Journal of Pharmacology. 172: 3370-82. PMID 25752739 DOI: 10.1111/Bph.13127  0.41
2015 Du F, Babcock JJ, Yu H, Zou B, Li M. Global analysis reveals families of chemical motifs enriched for HERG inhibitors. Plos One. 10: e0118324. PMID 25700001 DOI: 10.1371/Journal.Pone.0118324  0.367
2015 Zhang H, Zou B, Du F, Xu K, Li M. Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5. Molecular Pharmacology. 87: 207-17. PMID 25422141 DOI: 10.1124/Mol.114.094789  0.438
2014 Flaherty DP, Simpson DS, Miller M, Maki BE, Zou B, Shi J, Wu M, McManus OB, Aubé J, Li M, Golden JE. Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold. Bioorganic & Medicinal Chemistry Letters. 24: 3968-73. PMID 25017033 DOI: 10.1016/J.Bmcl.2014.06.032  0.315
2014 Bruner JK, Zou B, Zhang H, Zhang Y, Schmidt K, Li M. Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel. European Journal of Pharmacology. 740: 603-10. PMID 24972239 DOI: 10.1016/J.Ejphar.2014.06.021  0.435
2013 Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 8732-7. PMID 23650380 DOI: 10.1073/Pnas.1300684110  0.406
2012 Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL, Campbell CM, Balser JR, et al. Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias. The Journal of Biological Chemistry. 287: 39613-25. PMID 23033485 DOI: 10.1074/Jbc.M112.380162  0.367
2012 Cheung YY, Yu H, Xu K, Zou B, Wu M, McManus OB, Li M, Lindsley CW, Hopkins CR. Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor. Journal of Medicinal Chemistry. 55: 6975-9. PMID 22793372 DOI: 10.1021/Jm300700V  0.399
2012 Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F, Laugwitz KL, Li M. Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 109: 11866-71. PMID 22745159 DOI: 10.1073/Pnas.1205266109  0.362
2011 Du F, Yu H, Zou B, Babcock J, Long S, Li M. hERGCentral: a large database to store, retrieve, and analyze compound-human Ether-à-go-go related gene channel interactions to facilitate cardiotoxicity assessment in drug development. Assay and Drug Development Technologies. 9: 580-8. PMID 22149888 DOI: 10.1089/Adt.2011.0425  0.38
2011 Yu H, Wu M, Townsend SD, Zou B, Long S, Daniels JS, McManus OB, Li M, Lindsley CW, Hopkins CR. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. Acs Chemical Neuroscience. 2: 572-577. PMID 22125664 DOI: 10.1021/Cn200065B  0.42
2010 Zou B, Yu H, Babcock JJ, Chanda P, Bader JS, McManus OB, Li M. Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels. Assay and Drug Development Technologies. 8: 743-54. PMID 21158688 DOI: 10.1089/Adt.2010.0339  0.386
2004 Kawasaki F, Zou B, Xu X, Ordway RW. Active zone localization of presynaptic calcium channels encoded by the cacophony locus of Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 282-5. PMID 14715960 DOI: 10.1523/Jneurosci.3553-03.2004  0.342
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