Karen E. Gascoigne - Publications

Affiliations: 
2005-2008 Faculty of Life Sciences University of Manchester, Manchester, England, United Kingdom 
 2009-2014 Massachusetts Institute of Technology, Cambridge, MA, United States 
 2014- Genetech, Kota Kinabalu, Sabah, Malaysia 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Conery AR, Centore RC, Neiss A, Keller PJ, Joshi S, Spillane KL, Sandy P, Hatton C, Pardo E, Zawadzke L, Bommi-Reddy A, Gascoigne KE, Bryant BM, Mertz JA, Sims RJ. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. Elife. 5. PMID 26731516 DOI: 10.7554/eLife.10483  1
2015 Asundi J, Crocker L, Tremayne J, Chang P, Sakanaka C, Tanguay J, Spencer S, Chalasani S, Luis E, Gascoigne K, Desai R, Raja R, Friedman BA, Haverty PM, Polakis P, et al. An Antibody-Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3252-62. PMID 25862760 DOI: 10.1158/1078-0432.CCR-15-0156  1
2015 Rago F, Gascoigne KE, Cheeseman IM. Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T. Current Biology : Cb. 25: 671-7. PMID 25660545 DOI: 10.1016/j.cub.2015.01.059  1
2013 Gascoigne KE, Cheeseman IM. Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 407-18. PMID 23793898 DOI: 10.1007/s10577-013-9368-6  1
2013 Gascoigne KE, Cheeseman IM. CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state. The Journal of Cell Biology. 201: 23-32. PMID 23530067 DOI: 10.1083/jcb.201301006  1
2012 Gascoigne KE, Cheeseman IM. T time for point centromeres. Nature Cell Biology. 14: 559-61. PMID 22561349 DOI: 10.1038/ncb2509  1
2012 Nishino T, Takeuchi K, Gascoigne KE, Suzuki A, Hori T, Oyama T, Morikawa K, Cheeseman IM, Fukagawa T. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell. 148: 487-501. PMID 22304917 DOI: 10.1016/j.cell.2011.11.061  1
2011 Gascoigne KE, Takeuchi K, Suzuki A, Hori T, Fukagawa T, Cheeseman IM. Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes. Cell. 145: 410-22. PMID 21529714 DOI: 10.1016/j.cell.2011.03.031  1
2011 Gascoigne KE, Cheeseman IM. Kinetochore assembly: if you build it, they will come. Current Opinion in Cell Biology. 23: 102-8. PMID 20702077 DOI: 10.1016/j.ceb.2010.07.007  1
2009 Gascoigne KE, Taylor SS. How do anti-mitotic drugs kill cancer cells? Journal of Cell Science. 122: 2579-85. PMID 19625502 DOI: 10.1242/jcs.039719  1
2008 Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell. 14: 111-22. PMID 18656424 DOI: 10.1016/j.ccr.2008.07.002  1
2006 Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS. Validating Aurora B as an anti-cancer drug target. Journal of Cell Science. 119: 3664-75. PMID 16912073 DOI: 10.1242/jcs.03145  1
2005 Offman J, Gascoigne K, Bristow F, Macpherson P, Bignami M, Casorelli I, Leone G, Pagano L, Sica S, Halil O, Cummins D, Banner NR, Karran P. Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome Molecular Cancer Research. 3: 251-260. PMID 15886296 DOI: 10.1158/1541-7786.MCR-04-0182  1
2005 Kasza A, O'Donnell A, Gascoigne K, Zeef LA, Hayes A, Sharrocks AD. The ETS domain transcription factor Elk-1 regulates the expression of its partner protein, SRF. The Journal of Biological Chemistry. 280: 1149-55. PMID 15531578 DOI: 10.1074/jbc.M411161200  1
2005 Kasza A, O'Donnell A, Zeef L, Gascoigne K, Hayes A, Sharrocks AD. RhoA and MAPK pathways converge to regulate SRF gene expression Ukrain'Skyi Biokhimichnyi Zhurnal. 77: 183.  1
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