| Year |
Citation |
Score |
| 2020 |
Raisner R, Bainer R, Haverty PM, Benedetti KL, Gascoigne KE. Super-enhancer acquisition drives oncogene expression in triple negative breast cancer. Plos One. 15: e0235343. PMID 32584896 DOI: 10.1371/Journal.Pone.0235343 |
0.305 |
|
| 2019 |
de Almeida Nagata DE, Chiang EY, Jhunjhunwala S, Caplazi P, Arumugam V, Modrusan Z, Chan E, Merchant M, Jin L, Arnott D, Romero FA, Magnuson S, Gascoigne KE, Grogan JL. Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation. Cell Reports. 27: 269-281.e4. PMID 30943407 DOI: 10.1016/J.Celrep.2019.03.008 |
0.313 |
|
| 2018 |
Raisner R, Kharbanda S, Jin L, Jeng E, Chan E, Merchant M, Haverty PM, Bainer R, Cheung T, Arnott D, Flynn EM, Romero FA, Magnuson S, Gascoigne KE. Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation. Cell Reports. 24: 1722-1729. PMID 30110629 DOI: 10.1016/J.Celrep.2018.07.041 |
0.34 |
|
| 2018 |
Chang Y, Woessner DW, Lin W, Chen T, Xu B, Fan Y, Tan H, Peng J, Kasper L, Churchman ML, Gerhard DS, Loh ML, Hunger SP, Seth A, Gascoigne K, et al. Abstract IA12: Modeling and targeting CREBBP mutations in relapsed acute lymphoblastic leukemia Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Ia12 |
0.307 |
|
| 2018 |
Raisner R, Bainer R, Chan E, Garcia J, Merchant M, Gascoigne K. Abstract 1483: Targeting oncogenic enhancer activity with a small-molecule CBP/P300 bromodomain inhibitor Cancer Research. 78: 1483-1483. DOI: 10.1158/1538-7445.Am2018-1483 |
0.347 |
|
| 2017 |
Romero FA, Murray JM, Lai KW, Tsui V, Albrecht BK, An L, Beresini MH, de Leon Boenig G, Bronner SM, Chan EW, Chen KX, Chen Z, Choo EF, Clagg K, Clark K, ... ... Gascoigne KE, et al. GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). Journal of Medicinal Chemistry. PMID 28892380 DOI: 10.1021/Acs.Jmedchem.7B00796 |
0.301 |
|
| 2016 |
Crawford TD, Romero FA, Lai KW, Tsui V, Taylor AM, de Leon Boenig G, Noland CL, Murray J, Ly J, Choo EF, Hunsaker TL, Chan EW, Merchant M, Kharbanda S, Gascoigne KE, et al. Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. Journal of Medicinal Chemistry. PMID 27682507 DOI: 10.1021/Acs.Jmedchem.6B01022 |
0.325 |
|
| 2016 |
Conery AR, Centore RC, Neiss A, Keller PJ, Joshi S, Spillane KL, Sandy P, Hatton C, Pardo E, Zawadzke L, Bommi-Reddy A, Gascoigne KE, Bryant BM, Mertz JA, Sims RJ. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. Elife. 5. PMID 26731516 DOI: 10.7554/Elife.10483 |
0.345 |
|
| 2016 |
Keller PJ, Conery AR, Centore RC, Bommi-Reddy A, Gascoigne KE, Bryant BM, Mertz JA, Sims RJ. Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma Cancer Research. 76: 4749-4749. DOI: 10.1158/1538-7445.Am2016-4749 |
0.355 |
|
| 2015 |
Rago F, Gascoigne KE, Cheeseman IM. Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T. Current Biology : Cb. 25: 671-7. PMID 25660545 DOI: 10.1016/J.Cub.2015.01.059 |
0.629 |
|
| 2013 |
Gascoigne KE, Cheeseman IM. Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 407-18. PMID 23793898 DOI: 10.1007/S10577-013-9368-6 |
0.607 |
|
| 2013 |
Gascoigne KE, Cheeseman IM. CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state. The Journal of Cell Biology. 201: 23-32. PMID 23530067 DOI: 10.1083/Jcb.201301006 |
0.639 |
|
| 2012 |
Gascoigne KE, Cheeseman IM. T time for point centromeres. Nature Cell Biology. 14: 559-61. PMID 22561349 DOI: 10.1038/Ncb2509 |
0.597 |
|
| 2012 |
Nishino T, Takeuchi K, Gascoigne KE, Suzuki A, Hori T, Oyama T, Morikawa K, Cheeseman IM, Fukagawa T. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell. 148: 487-501. PMID 22304917 DOI: 10.1016/J.Cell.2011.11.061 |
0.618 |
|
| 2011 |
Gascoigne KE, Takeuchi K, Suzuki A, Hori T, Fukagawa T, Cheeseman IM. Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes. Cell. 145: 410-22. PMID 21529714 DOI: 10.1016/J.Cell.2011.03.031 |
0.664 |
|
| 2011 |
Gascoigne KE, Cheeseman IM. Kinetochore assembly: if you build it, they will come. Current Opinion in Cell Biology. 23: 102-8. PMID 20702077 DOI: 10.1016/J.Ceb.2010.07.007 |
0.633 |
|
| 2009 |
Gascoigne KE, Taylor SS. How do anti-mitotic drugs kill cancer cells? Journal of Cell Science. 122: 2579-85. PMID 19625502 DOI: 10.1242/Jcs.039719 |
0.475 |
|
| 2008 |
Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell. 14: 111-22. PMID 18656424 DOI: 10.1016/J.Ccr.2008.07.002 |
0.482 |
|
| 2006 |
Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS. Validating Aurora B as an anti-cancer drug target. Journal of Cell Science. 119: 3664-75. PMID 16912073 DOI: 10.1242/Jcs.03145 |
0.508 |
|
| 2005 |
Kasza A, O'Donnell A, Gascoigne K, Zeef LA, Hayes A, Sharrocks AD. The ETS domain transcription factor Elk-1 regulates the expression of its partner protein, SRF. The Journal of Biological Chemistry. 280: 1149-55. PMID 15531578 DOI: 10.1074/Jbc.M411161200 |
0.318 |
|
| Show low-probability matches. |