G. Stanley McKnight - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
protein kinase A, signal transduction

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, McKnight GS, Breault DT, Lefrançois-Martinez AM, Martinez A, Eyers CE, et al. Mislocalization of protein kinase A drives pathology in Cushing's syndrome. Cell Reports. 40: 111073. PMID 35830806 DOI: 10.1016/j.celrep.2022.111073  0.33
2022 Wang X, Jiang L, Thao K, Sussman C, LaBranche T, Palmer M, Harris P, McKnight GS, Hoeflich K, Schalm S, Torres V. Protein Kinase A Downregulation Delays the Development and Progression of Polycystic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 35236775 DOI: 10.1681/ASN.2021081125  0.302
2019 Sanz E, Bean JC, Carey DP, Quintana A, McKnight GS. RiboTag: Ribosomal Tagging Strategy to Analyze Cell-Type-Specific mRNA Expression In Vivo. Current Protocols in Neuroscience. 88: e77. PMID 31216392 DOI: 10.1002/Cpns.77  0.377
2018 Flippo KH, Gnanasekaran A, Perkins GA, Ahmad A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S. AKAP1 protects from cerebral ischemic stroke by inhibiting Drp1-dependent mitochondrial fission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30093535 DOI: 10.1523/Jneurosci.0649-18.2018  0.334
2016 Jones BW, Deem J, Younts TJ, Weisenhaus M, Sanford CA, Slack MC, Chin J, Nachmanson D, McKennon A, Castillo PE, McKnight GS. Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination. Elife. 5. PMID 27911261 DOI: 10.7554/Elife.20695  0.367
2016 Riggle KM, Riehle KJ, Kenerson HL, Turnham R, Homma MK, Kazami M, Samelson B, Bauer R, McKnight GS, Scott JD, Yeung RS. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Pediatric Research. PMID 27027723 DOI: 10.1038/Pr.2016.36  0.334
2015 Yang L, McKnight GS. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nature Communications. 6: 8237. PMID 26381935 DOI: 10.1038/Ncomms9237  0.409
2015 Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS. Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5549-56. PMID 25855171 DOI: 10.1523/Jneurosci.3614-14.2015  0.443
2015 Gilbert ML, Yang L, Su T, McKnight GS. Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype. American Journal of Physiology. Renal Physiology. 308: F627-38. PMID 25587115 DOI: 10.1152/Ajprenal.00222.2014  0.433
2014 Yang L, Gilbert ML, Zheng R, McKnight GS. Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4896-904. PMID 24695708 DOI: 10.1523/Jneurosci.3460-13.2014  0.488
2013 Wu Q, Zheng R, Srisai D, McKnight GS, Palmiter RD. NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Proceedings of the National Academy of Sciences of the United States of America. 110: 14765-70. PMID 23964123 DOI: 10.1073/Pnas.1314137110  0.339
2013 Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS. RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo. Plos One. 8: e66179. PMID 23776628 DOI: 10.1371/Journal.Pone.0066179  0.335
2013 Zheng R, Yang L, Sikorski MA, Enns LC, Czyzyk TA, Ladiges WC, McKnight GS. Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations. Proceedings of the National Academy of Sciences of the United States of America. 110: E1631-40. PMID 23569242 DOI: 10.1073/Pnas.1219542110  0.368
2012 Quintana A, Sanz E, Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nature Neuroscience. 15: 1547-55. PMID 23064379 DOI: 10.1038/Nn.3239  0.307
2012 Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS. Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 17099-104. PMID 23035250 DOI: 10.1073/Pnas.1215219109  0.334
2011 Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology. 152: 4298-309. PMID 21933870 DOI: 10.1210/En.2011-1521  0.503
2011 Willis BS, Niswender CM, Su T, Amieux PS, McKnight GS. Cell-type specific expression of a dominant negative PKA mutation in mice. Plos One. 6: e18772. PMID 21533282 DOI: 10.1371/Journal.Pone.0018772  0.395
2010 Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circulation Research. 107: 747-56. PMID 20671242 DOI: 10.1161/Circresaha.109.216127  0.348
2010 Weisenhaus M, Allen ML, Yang L, Lu Y, Nichols CB, Su T, Hell JW, McKnight GS. Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. Plos One. 5: e10325. PMID 20428246 DOI: 10.1371/Journal.Pone.0010325  0.411
2010 Wu CY, DiJulio DH, Jacobson KL, McKnight GS, Watson EL. The contribution of AKAP5 in amylase secretion from mouse parotid acini. American Journal of Physiology. Cell Physiology. 298: C1151-8. PMID 20164376 DOI: 10.1152/Ajpcell.00382.2009  0.454
2010 Amieux PS, McKnight GS. Cyclic nucleotides converge on brown adipose tissue differentiation. Science Signaling. 3: pe2. PMID 20068229 DOI: 10.1126/Scisignal.3104Pe2  0.337
2009 Sanz E, Yang L, Su T, Morris DR, McKnight GS, Amieux PS. Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. Proceedings of the National Academy of Sciences of the United States of America. 106: 13939-44. PMID 19666516 DOI: 10.1073/Pnas.0907143106  0.402
2009 Morgans CW, Kensel-Hammes P, Hurley JB, Burton K, Idzerda R, McKnight GS, Bajjalieh SM. Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina. Plos One. 4: e5230. PMID 19381277 DOI: 10.1371/Journal.Pone.0005230  0.3
2009 Vuong BQ, Lee M, Kabir S, Irimia C, Macchiarulo S, McKnight GS, Chaudhuri J. Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination. Nature Immunology. 10: 420-6. PMID 19234474 DOI: 10.1038/Ni.1708  0.4
2008 Morgan DJ, Weisenhaus M, Shum S, Su T, Zheng R, Zhang C, Shokat KM, Hille B, Babcock DF, McKnight GS. Tissue-specific PKA inhibition using a chemical genetic approach and its application to studies on sperm capacitation. Proceedings of the National Academy of Sciences of the United States of America. 105: 20740-5. PMID 19074277 DOI: 10.1073/Pnas.0810971105  0.483
2008 Lu Y, Zhang M, Lim IA, Hall DD, Allen M, Medvedeva Y, McKnight GS, Usachev YM, Hell JW. AKAP150-anchored PKA activity is important for LTD during its induction phase. The Journal of Physiology. 586: 4155-64. PMID 18617570 DOI: 10.1113/Jphysiol.2008.151662  0.405
2008 Schnizler K, Shutov LP, Van Kanegan MJ, Merrill MA, Nichols B, McKnight GS, Strack S, Hell JW, Usachev YM. Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4904-17. PMID 18463244 DOI: 10.1523/Jneurosci.0233-08.2008  0.471
2008 Alizadeh A, Fitch KR, Niswender CM, McKnight GS, Barsh GS. Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements. Pigment Cell & Melanoma Research. 21: 63-9. PMID 18353144 DOI: 10.1111/J.1755-148X.2007.00425.X  0.43
2008 Czyzyk TA, Sikorski MA, Yang L, McKnight GS. Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 276-81. PMID 18172198 DOI: 10.1073/Pnas.0710607105  0.426
2007 Lu Y, Allen M, Halt AR, Weisenhaus M, Dallapiazza RF, Hall DD, Usachev YM, McKnight GS, Hell JW. Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. The Embo Journal. 26: 4879-90. PMID 17972919 DOI: 10.1038/Sj.Emboj.7601884  0.375
2007 Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nature Cell Biology. 9: 415-21. PMID 17369818 DOI: 10.1038/Ncb1561  0.445
2007 Burton KA, McKnight GS. PKA, germ cells, and fertility. Physiology (Bethesda, Md.). 22: 40-6. PMID 17289929 DOI: 10.1152/Physiol.00034.2006  0.35
2007 Hall DD, Davare MA, Shi M, Allen ML, Weisenhaus M, McKnight GS, Hell JW. Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 46: 1635-46. PMID 17279627 DOI: 10.1021/Bi062217X  0.481
2006 Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/Syn.20303  0.3
2006 Burton KA, McDermott DA, Wilkes D, Poulsen MN, Nolan MA, Goldstein M, Basson CT, McKnight GS. Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men. Molecular Endocrinology (Baltimore, Md.). 20: 2504-13. PMID 16728532 DOI: 10.1210/Me.2006-0060  0.411
2006 Watson RF, Abdel-Majid RM, Barnett MW, Willis BS, Katsnelson A, Gillingwater TH, McKnight GS, Kind PC, Neumann PE. Involvement of protein kinase A in patterning of the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5393-401. PMID 16707791 DOI: 10.1523/Jneurosci.0750-06.2006  0.45
2006 Newhall KJ, Criniti AR, Cheah CS, Smith KC, Kafer KE, Burkart AD, McKnight GS. Dynamic anchoring of PKA is essential during oocyte maturation. Current Biology : Cb. 16: 321-7. PMID 16461287 DOI: 10.1016/J.Cub.2005.12.031  0.388
2006 Howe DG, Clarke CM, Yan H, Willis BS, Schneider DA, McKnight GS, Kapur RP. Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction. Journal of Neurobiology. 66: 256-72. PMID 16329126 DOI: 10.1002/Neu.20217  0.414
2006 Schuh SM, Carlson AE, McKnight GS, Conti M, Hille B, Babcock DF. Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists. Biology of Reproduction. 74: 492-500. PMID 16291925 DOI: 10.1095/Biolreprod.105.047837  0.412
2005 Niswender CM, Willis BS, Wallen A, Sweet IR, Jetton TL, Thompson BR, Wu C, Lange AJ, McKnight GS. Cre recombinase-dependent expression of a constitutively active mutant allele of the catalytic subunit of protein kinase A. Genesis (New York, N.Y. : 2000). 43: 109-19. PMID 16155866 DOI: 10.1002/Gene.20159  0.486
2005 Schillace RV, Andrews SF, Galligan SG, Burton KA, Starks HJ, Bouwer HG, McKnight GS, Davey MP, Carr DW. The role of protein kinase A anchoring via the RII alpha regulatory subunit in the murine immune system. Journal of Immunology (Baltimore, Md. : 1950). 174: 6847-53. PMID 15905526 DOI: 10.4049/Jimmunol.174.11.6847  0.42
2005 Newhall KJ, Cummings DE, Nolan MA, McKnight GS. Deletion of the RIIbeta-subunit of protein kinase A decreases body weight and increases energy expenditure in the obese, leptin-deficient ob/ob mouse. Molecular Endocrinology (Baltimore, Md.). 19: 982-91. PMID 15618289 DOI: 10.1210/Me.2004-0343  0.375
2004 Fischer QS, Beaver CJ, Yang Y, Rao Y, Jakobsdottir KB, Storm DR, McKnight GS, Daw NW. Requirement for the RIIbeta isoform of PKA, but not calcium-stimulated adenylyl cyclase, in visual cortical plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9049-58. PMID 15483123 DOI: 10.1523/Jneurosci.2409-04.2004  0.39
2004 Veugelers M, Wilkes D, Burton K, McDermott DA, Song Y, Goldstein MM, La Perle K, Vaughan CJ, O'Hagan A, Bennett KR, Meyer BJ, Legius E, Karttunen M, Norio R, Kaariainen H, ... ... McKnight GS, et al. Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 14222-7. PMID 15371594 DOI: 10.1073/Pnas.0405535101  0.341
2004 Nolan MA, Babcock DF, Wennemuth G, Brown W, Burton KA, McKnight GS. Sperm-specific protein kinase A catalytic subunit Calpha2 orchestrates cAMP signaling for male fertility. Proceedings of the National Academy of Sciences of the United States of America. 101: 13483-8. PMID 15340140 DOI: 10.1073/Pnas.0405580101  0.445
2004 Rao Y, Fischer QS, Yang Y, McKnight GS, LaRue A, Daw NW. Reduced ocular dominance plasticity and long-term potentiation in the developing visual cortex of protein kinase A RII alpha mutant mice. The European Journal of Neuroscience. 20: 837-42. PMID 15255994 DOI: 10.1111/J.1460-9568.2004.03499.X  0.369
2004 Nolan MA, Sikorski MA, McKnight GS. The role of uncoupling protein 1 in the metabolism and adiposity of RII beta-protein kinase A-deficient mice. Molecular Endocrinology (Baltimore, Md.). 18: 2302-11. PMID 15192081 DOI: 10.1210/Me.2004-0194  0.377
2002 Howe DG, Wiley JC, McKnight GS. Molecular and behavioral effects of a null mutation in all PKA C beta isoforms. Molecular and Cellular Neurosciences. 20: 515-24. PMID 12139926 DOI: 10.1006/Mcne.2002.1119  0.435
2002 Amieux PS, McKnight GS. The essential role of RI alpha in the maintenance of regulated PKA activity. Annals of the New York Academy of Sciences. 968: 75-95. PMID 12119269 DOI: 10.1111/J.1749-6632.2002.Tb04328.X  0.406
2002 Niswender CM, Ishihara RW, Judge LM, Zhang C, Shokat KM, McKnight GS. Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity. The Journal of Biological Chemistry. 277: 28916-22. PMID 12034735 DOI: 10.1074/Jbc.M203327200  0.457
2002 Amieux PS, Howe DG, Knickerbocker H, Lee DC, Su T, Laszlo GS, Idzerda RL, McKnight GS. Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo. The Journal of Biological Chemistry. 277: 27294-304. PMID 12004056 DOI: 10.1074/Jbc.M200302200  0.416
2002 Huang Y, Roelink H, McKnight GS. Protein kinase A deficiency causes axially localized neural tube defects in mice. The Journal of Biological Chemistry. 277: 19889-96. PMID 11886853 DOI: 10.1074/Jbc.M111412200  0.391
2002 Skålhegg BS, Huang Y, Su T, Idzerda RL, McKnight GS, Burton KA. Mutation of the Calpha subunit of PKA leads to growth retardation and sperm dysfunction. Molecular Endocrinology (Baltimore, Md.). 16: 630-9. PMID 11875122 DOI: 10.1210/Mend.16.3.0793  0.469
2001 Schreyer SA, Cummings DE, McKnight GS, LeBoeuf RC. Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice. Diabetes. 50: 2555-62. PMID 11679434 DOI: 10.2337/Diabetes.50.11.2555  0.348
2000 Wu JY, Ribar TJ, Cummings DE, Burton KA, McKnight GS, Means AR. Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. Nature Genetics. 25: 448-52. PMID 10932193 DOI: 10.1038/78153  0.338
2000 Desseyn JL, Burton KA, McKnight GS. Expression of a nonmyristylated variant of the catalytic subunit of protein kinase A during male germ-cell development. Proceedings of the National Academy of Sciences of the United States of America. 97: 6433-8. PMID 10841548 DOI: 10.1073/Pnas.97.12.6433  0.479
2000 Gangolli EA, Belyamani M, Muchinsky S, Narula A, Burton KA, McKnight GS, Uhler MD, Idzerda RL. Deficient gene expression in protein kinase inhibitor alpha Null mutant mice. Molecular and Cellular Biology. 20: 3442-8. PMID 10779334 DOI: 10.1128/Mcb.20.10.3442-3448.2000  0.719
1999 Planas JV, Cummings DE, Idzerda RL, McKnight GS. Mutation of the RIIbeta subunit of protein kinase A differentially affects lipolysis but not gene induction in white adipose tissue. The Journal of Biological Chemistry. 274: 36281-7. PMID 10593917 DOI: 10.1074/Jbc.274.51.36281  0.475
1999 Burton KA, Treash-Osio B, Muller CH, Dunphy EL, McKnight GS. Deletion of type IIα regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization Journal of Biological Chemistry. 274: 24131-24136. PMID 10446185 DOI: 10.1074/Jbc.274.34.24131  0.451
1999 Wiley JC, Wailes LA, Idzerda RL, McKnight GS. Role of regulatory subunits and protein kinase inhibitor (PKI) in determining nuclear localization and activity of the catalytic subunit of protein kinase A. The Journal of Biological Chemistry. 274: 6381-7. PMID 10037729 DOI: 10.1074/Jbc.274.10.6381  0.476
1998 McKnight GS, Cummings DE, Amieux PS, Sikorski MA, Brandon EP, Planas JV, Motamed K, Idzerda RL. Cyclic AMP, PKA, and the physiological regulation of adiposity. Recent Progress in Hormone Research. 53: 139-59; discussion 1. PMID 9769707  0.317
1998 Brandon EP, Logue SF, Adams MR, Qi M, Sullivan SP, Matsumoto AM, Dorsa DM, Wehner JM, McKnight GS, Idzerda RL. Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3639-49. PMID 9570795  0.336
1998 Hensch TK, Gordon JA, Brandon EP, McKnight GS, Idzerda RL, Stryker MP. Comparison of plasticity in vivo and in vitro in the developing visual cortex of normal and protein kinase A RIbeta-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2108-17. PMID 9482797 DOI: 10.1523/Jneurosci.18-06-02108.1998  0.373
1998 Brandon EP, Logue SF, Adams MR, Qi M, Sullivan SP, Matsumoto AM, Dorsa DM, Wehner JM, McKnight GS, Idzerda RL. Defective Motor Behavior and Neural Gene Expression in RIIβ-Protein Kinase A Mutant Mice The Journal of Neuroscience. 18: 3639-3649. DOI: 10.1523/Jneurosci.18-10-03639.1998  0.44
1997 Burton KA, Johnson BD, Hausken ZE, Westenbroek RE, Idzerda RL, Scheuer T, Scott JD, Catterall WA, McKnight GS. Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 11067-72. PMID 9380760 DOI: 10.1073/pnas.94.20.11067  0.329
1997 Hamilton SE, Loose MD, Qi M, Levey AI, Hille B, McKnight GS, Idzerda RL, Nathanson NM. Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13311-6. PMID 9371842 DOI: 10.1073/Pnas.94.24.13311  0.325
1997 Guthrie CR, Skâlhegg BS, McKnight GS. Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 272: 29560-5. PMID 9368018 DOI: 10.1074/Jbc.272.47.29560  0.476
1997 Adams MR, Brandon EP, Chartoff EH, Idzerda RL, Dorsa DM, McKnight GS. Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 12157-61. PMID 9342379 DOI: 10.1073/Pnas.94.22.12157  0.499
1997 Malmberg AB, Brandon EP, Idzerda RL, Liu H, McKnight GS, Basbaum AI. Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7462-70. PMID 9295392 DOI: 10.1523/Jneurosci.17-19-07462.1997  0.332
1997 Brandon EP, Idzerda RL, McKnight GS. PKA isoforms, neural pathways, and behaviour: making the connection. Current Opinion in Neurobiology. 7: 397-403. PMID 9232801 DOI: 10.1016/S0959-4388(97)80069-4  0.472
1997 Amieux PS, Cummings DE, Motamed K, Brandon EP, Wailes LA, Le K, Idzerda RL, McKnight GS. Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice. The Journal of Biological Chemistry. 272: 3993-8. PMID 9020105 DOI: 10.1074/Jbc.272.7.3993  0.516
1996 Matthews RP, McKnight GS. Characterization of the cAMP response element of the cystic fibrosis transmembrane conductance regulator gene promoter. The Journal of Biological Chemistry. 271: 31869-77. PMID 8943230 DOI: 10.1074/Jbc.271.50.31869  0.432
1996 Cummings DE, Brandon EP, Planas JV, Motamed K, Idzerda RL, McKnight GS. Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A. Nature. 382: 622-6. PMID 8757131 DOI: 10.1038/382622A0  0.432
1996 Qi M, Zhuo M, SkÃ¥lhegg BS, Brandon EP, Kandel ER, McKnight GS, Idzerda RL. Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 93: 1571-6. PMID 8643673 DOI: 10.1073/Pnas.93.4.1571  0.333
1996 McKnight GS. Genetically lean mice derived by targeted disruption of the rllβ subuntt of protein kinase Journal of Investigative Medicine. 44: 197a.  0.342
1995 Gjertsen BT, Mellgren G, Otten A, Maronde E, Genieser HG, Jastorff B, Vintermyr OK, McKnight GS, Døskeland SO. Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action. The Journal of Biological Chemistry. 270: 20599-607. PMID 7657638 DOI: 10.1074/Jbc.270.35.20599  0.467
1995 Brandon EP, Zhuo M, Huang YY, Qi M, Gerhold KA, Burton KA, Kandel ER, McKnight GS, Idzerda RL. Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 92: 8851-5. PMID 7568030 DOI: 10.1073/Pnas.92.19.8851  0.351
1995 McDonald RA, Matthews RP, Idzerda RL, McKnight GS. Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity. Proceedings of the National Academy of Sciences of the United States of America. 92: 7560-4. PMID 7543684 DOI: 10.1073/pnas.92.16.7560  0.361
1994 Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Molecular and Cellular Biology. 14: 6107-16. PMID 8065343 DOI: 10.1128/Mcb.14.9.6107  0.342
1994 Cummings DE, Edelhoff S, Disteche CM, McKnight GS. Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 701-6. PMID 7873880 DOI: 10.1007/Bf00426076  0.324
1993 Orellana SA, Amieux PS, Zhao X, McKnight GS. Mutations in the catalytic subunit of the cAMP-dependent protein kinase interfere with holoenzyme formation without disrupting inhibition by protein kinase inhibitor. The Journal of Biological Chemistry. 268: 6843-6. PMID 8463209  0.373
1992 Clegg CH, Abrahamsen MS, Degen JL, Morris DR, McKnight GS. Cyclic AMP-dependent protein kinase controls basal gene activity and steroidogenesis in Y1 adrenal tumor cells. Biochemistry. 31: 3720-6. PMID 1567825  0.453
1992 Rogers KV, Boring LF, McKnight GS, Clegg CH. Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system. Molecular Endocrinology (Baltimore, Md.). 6: 1756-65. PMID 1448119 DOI: 10.1210/mend.6.10.1448119  0.305
1991 Wang YH, Scott JD, McKnight GS, Krebs EG. A constitutively active holoenzyme form of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 2446-50. PMID 1848703  0.338
1991 Otten AD, Parenteau LA, Døskeland S, McKnight GS. Hormonal activation of gene transcription in ras-transformed NIH3T3 cells overexpressing RII alpha and RII beta subunits of the cAMP-dependent protein kinase. The Journal of Biological Chemistry. 266: 23074-82. PMID 1744104  0.367
1991 McKnight GS. Cyclic AMP second messenger systems. Current Opinion in Cell Biology. 3: 213-7. PMID 1652989 DOI: 10.1016/0955-0674(91)90141-K  0.408
1991 Schecterson LC, McKnight GS. Role of cyclic adenosine 3',5'-monophosphate-dependent protein kinase in hormone-stimulated beta-endorphin secretion in AtT20 cells. Molecular Endocrinology (Baltimore, Md.). 5: 170-8. PMID 1645451 DOI: 10.1210/Mend-5-2-170  0.483
1990 Cadd G, McKnight GS. Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain. Neuron. 3: 71-9. PMID 2619996 DOI: 10.1016/0896-6273(89)90116-5  0.429
1990 Orellana SA, McKnight GS. The S49 Kin- cell line transcribes and translates a functional mRNA coding for the catalytic subunit of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 265: 3048-53. PMID 2303438  0.366
1990 Rogers KV, Goldman PS, Frizzell RA, McKnight GS. Regulation of Cl- transport in T84 cell clones expressing a mutant regulatory subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 87: 8975-9. PMID 2174170  0.356
1990 Cadd GG, Uhler MD, McKnight GS. Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. The Journal of Biological Chemistry. 265: 19502-6. PMID 2174040  0.633
1989 Otten AD, McKnight GS. Overexpression of the type II regulatory subunit of the cAMP-dependent protein kinase eliminates the type I holoenzyme in mouse cells. The Journal of Biological Chemistry. 264: 20255-60. PMID 2584216  0.344
1989 Clegg CH, Ran W, Uhler MD, McKnight GS. A mutation in the catalytic subunit of protein kinase A prevents myristylation but does not inhibit biological activity. The Journal of Biological Chemistry. 264: 20140-6. PMID 2584209  0.68
1989 Correll LA, Woodford TA, Corbin JD, Mellon PL, McKnight GS. Functional characterization of cAMP-binding mutations in type I protein kinase Journal of Biological Chemistry. 264: 16672-16678. PMID 2550452  0.305
1989 Mellon PL, Clegg CH, Correll LA, McKnight GS. Regulation of transcription by cyclic AMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 86: 4887-4891. PMID 2544878  0.401
1988 Clegg CH, Cadd GG, McKnight GS. Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 85: 3703-3707. PMID 3375237  0.393
1988 Oyen O, Scott JD, Cadd GG, McKnight GS, Krebs EG, Hansson V, Jahnsen T. A unique mRNA species for a regulatory subunit of cAMP-dependent protein kinase is specifically induced in haploid germ cells. Febs Letters. 229: 391-4. PMID 3345850 DOI: 10.1016/0014-5793(88)81163-3  0.51
1988 McKnight GS, Cadd GG, Clegg CH, Otten AD, Correll LA. Expression of wild-type and mutant subunits of the cAMP-dependent protein kinase Cold Spring Harbor Symposia On Quantitative Biology. 53: 111-119. PMID 3254772  0.375
1988 McKnight GS, Clegg CH, Uhler MD, Chrivia JC, Cadd GG, Correll LA, Otten AD. Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches Recent Progress in Hormone Research. 44: 307-335. PMID 3217600  0.623
1988 Sanders MM, McKnight GS. Positive and negative regulatory elements control the steroid-responsive ovalbumin promoter Biochemistry. 27: 6550-6557. PMID 3064812 DOI: 10.1021/Bi00417A053  0.353
1988 McKnight GS, Uhler MD, Clegg CH, Correll LA, Cadd GG. Application of molecular genetic techniques to the cAMP-dependent protein kinase system Methods in Enzymology. 159: 299-311. PMID 2842597 DOI: 10.1016/0076-6879(88)59030-4  0.7
1988 Otten AD, Sanders MM, McKnight GS. The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen Molecular Endocrinology. 2: 143-147. PMID 2840570 DOI: 10.1210/Mend-2-2-143  0.303
1988 Chrivia JC, Uhler MD, McKnight GS. Characterization of genomic clones coding for the Cα and Cβ subunits of mouse cAMP-dependent protein kinase Journal of Biological Chemistry. 263: 5739-5744. PMID 2833513  0.644
1987 Uhler MD, McKnight GS. Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase Journal of Biological Chemistry. 262: 15202-15207. PMID 3667630  0.655
1987 Scott JD, Glaccum MB, Zoller MJ, Uhler MD, Helfman DM, McKnight GS, Krebs EG. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 84: 5192-6. PMID 3037538 DOI: 10.1073/Pnas.84.15.5192  0.633
1987 Clegg CH, Correll LA, Cadd GG, McKnight GS. Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit Journal of Biological Chemistry. 262: 13111-13119. PMID 2820963  0.417
1986 Uhler MD, Carmichael DF, Lee DC, Chrivia JC, Krebs EG, McKnight GS. Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 1300-4. PMID 3456589 DOI: 10.1073/Pnas.83.5.1300  0.663
1986 Uhler MD, Chrivia JC, McKnight GS. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase Journal of Biological Chemistry. 261: 15360-15363. PMID 3023318  0.665
1985 Sanders MM, McKnight GS. Chicken egg white genes: Multihormonal regulation in a primary cell culture system Endocrinology. 116: 398-405. PMID 3880544 DOI: 10.1210/Endo-116-1-398  0.334
1983 McKnight GS, Hammer RE, Kuenzel EA, Brinster RL. Expression of the chicken transferrin gene in transgenic mice. Cell. 34: 335-41. PMID 6311428 DOI: 10.1016/0092-8674(83)90368-9  0.36
1983 Lee DC, Carmichael DF, Krebs EG, McKnight GS. Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 80: 3608-12. PMID 6190178  0.32
1981 Evans MI, Hager LJ, McKnight GS. A somatomedin-like peptide hormone is required during the estrogen-mediated induction of ovalbumin gene transcription Cell. 25: 187-193. PMID 7023694 DOI: 10.1016/0092-8674(81)90243-9  0.306
1980 McKnight GS, Hager L, Palmiter RD. Butyrate and related inhibitors of histone deacetylation block the induction of egg white genes by steroid hormones Cell. 22: 469-477. PMID 7448870 DOI: 10.1016/0092-8674(80)90357-8  0.355
1978 McKnight GS. The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant cultures. Cell. 14: 403-13. PMID 566622 DOI: 10.1016/0092-8674(78)90125-3  0.343
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