Daniel Portnoy - Publications

Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Molecular and cellular basis of microbial pathogenesis

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Berude JC, Kennouche P, Reniere ML, Portnoy DA. utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine. Infection and Immunity. e0042223. PMID 38289071 DOI: 10.1128/iai.00422-23  0.327
2023 Berude JC, Kennouche P, Reniere ML, Portnoy DA. utilizes glutathione and limited inorganic sulfur compounds as a source of essential L-cysteine. Biorxiv : the Preprint Server For Biology. PMID 37905006 DOI: 10.1101/2023.10.16.562582  0.363
2023 Morrison HM, Craft J, Rivera-Lugo R, Johnson JR, Golovkine GR, Bell SL, Dodd CE, Van Dis E, Beatty WL, Margolis SR, Repasy T, Shaker I, Lee AY, Vance RE, Stanley SA, ... ... Portnoy DA, et al. Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens. Plos Pathogens. 19: e1011088. PMID 37352334 DOI: 10.1371/journal.ppat.1011088  0.382
2022 Zhang Y, Anaya-Sanchez A, Portnoy DA. -Aminobenzoic Acid Biosynthesis Is Required for Listeria monocytogenes Growth and Pathogenesis. Infection and Immunity. 90: e0020722. PMID 36317877 DOI: 10.1128/iai.00207-22  0.364
2022 Rivera-Lugo R, Deng D, Anaya-Sanchez A, Tejedor-Sanz S, Tang E, Reyes Ruiz VM, Smith HB, Titov DV, Sauer JD, Skaar EP, Ajo-Franklin CM, Portnoy DA, Light SH. requires cellular respiration for NAD regeneration and pathogenesis. Elife. 11. PMID 35380108 DOI: 10.7554/eLife.75424  0.809
2022 Rivera-Lugo R, Light SH, Garelis NE, Portnoy DA. RibU is an essential determinant of pathogenesis that mediates acquisition of FMN and FAD during intracellular growth. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122173119. PMID 35316134 DOI: 10.1073/pnas.2122173119  0.43
2021 Anaya-Sanchez A, Feng Y, Berude JC, Portnoy DA. Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes. Plos Pathogens. 17: e1009819. PMID 34407151 DOI: 10.1371/journal.ppat.1009819  0.407
2020 Louie A, Bhandula V, Portnoy DA. Secretion of c-di-AMP by leads to a STING-dependent antibacterial response during enterocolitis. Infection and Immunity. PMID 33020211 DOI: 10.1128/IAI.00407-20  0.391
2020 Peterson BN, Portman JL, Feng Y, Wang J, Portnoy DA. Secondary structure of the mRNA encoding listeriolysin O is essential to establish the replicative niche of . Proceedings of the National Academy of Sciences of the United States of America. PMID 32878997 DOI: 10.1073/pnas.2004129117  0.318
2020 Nguyen BN, Chávez-Arroyo A, Cheng MI, Krasilnikov M, Louie A, Portnoy DA. TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes. Plos Pathogens. 16: e1008622. PMID 32634175 DOI: 10.1371/journal.ppat.1008622  0.302
2020 Chávez-Arroyo A, Portnoy DA. Why is Listeria monocytogenes such a potent inducer of CD8+ T-cells? Cellular Microbiology. 22: e13175. PMID 32185899 DOI: 10.1111/cmi.13175  0.43
2020 Nguyen BN, Portnoy DA. An Inducible Cre- System to Analyze the Role of LLO in Pathogenesis. Toxins. 12. PMID 31936068 DOI: 10.3390/toxins12010038  0.397
2019 Hanson WG, Benanti EL, Lemmens EE, Liu W, Skoble J, Leong ML, Rae CS, Fassò M, Brockstedt DG, Chen C, Portnoy DA, Dubensky TW, Lauer P. A potent and effective suicidal vaccine platform. Infection and Immunity. PMID 31235641 DOI: 10.1128/Iai.00144-19  0.78
2018 Nguyen BN, Peterson BN, Portnoy DA. Listeriolysin O: a phagosome-specific cytolysin revisited. Cellular Microbiology. e12988. PMID 30511471 DOI: 10.1111/cmi.12988  0.391
2018 Deng W, Lira V, Hudson TE, Lemmens EE, Hanson WG, Flores R, Barajas G, Katibah GE, Desbien AL, Lauer P, Leong ML, Portnoy DA, Dubensky TW. Recombinant promotes tumor rejection by CD8 T cell-dependent remodeling of the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. PMID 30038013 DOI: 10.1073/Pnas.1801910115  0.638
2018 Cheng MI, Chen C, Engström P, Portnoy DA, Mitchell G. Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol. Cellular Microbiology. e12854. PMID 29726107 DOI: 10.1111/cmi.12854  0.359
2018 Van Dis E, Sogi KM, Rae CS, Sivick KE, Surh NH, Leong ML, Kanne DB, Metchette K, Leong JJ, Bruml JR, Chen V, Heydari K, Cadieux N, Evans T, McWhirter SM, ... ... Portnoy DA, et al. STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection. Cell Reports. 23: 1435-1447. PMID 29719256 DOI: 10.1016/J.Celrep.2018.04.003  0.302
2017 Mitchell G, Cheng MI, Chen C, Nguyen BN, Whiteley AT, Kianian S, Cox JS, Green DR, McDonald KL, Portnoy DA. Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279409 DOI: 10.1073/Pnas.1716055115  0.407
2017 Portman JL, Dubensky SB, Peterson BN, Whiteley AT, Portnoy DA. Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment. Mbio. 8. PMID 29042499 DOI: 10.1128/mBio.01595-17  0.472
2017 Portman JL, Huang Q, Reniere ML, Iavarone AT, Portnoy DA. Activity of the pore-forming virulence factor Listeriolysin O is reversibly inhibited by naturally occurring S-glutathionylation. Infection and Immunity. PMID 28138025 DOI: 10.1128/Iai.00959-16  0.326
2016 Reniere ML, Whiteley AT, Portnoy DA. An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression. Plos Pathogens. 12: e1005741. PMID 27414028 DOI: 10.1371/journal.ppat.1005741  0.385
2016 Mitchell G, Chen C, Portnoy DA. Strategies Used by Bacteria to Grow in Macrophages. Microbiology Spectrum. 4. PMID 27337444 DOI: 10.1128/microbiolspec.MCHD-0012-2015  0.408
2015 Whiteley AT, Pollock AJ, Portnoy DA. The PAMP c-di-AMP Is Essential for Listeria Growth in Macrophages and Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp. Cell Host & Microbe. 17: 788-98. PMID 26028365 DOI: 10.1016/j.chom.2015.05.006  0.32
2015 Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, et al. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade. Science Translational Medicine. 7: 283ra52. PMID 25877890 DOI: 10.1126/Scitranslmed.Aaa4306  0.667
2015 Mitchell G, Ge L, Huang Q, Chen C, Kianian S, Roberts MF, Schekman R, Portnoy DA. Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages. Infection and Immunity. 83: 2175-84. PMID 25776746 DOI: 10.1128/Iai.00110-15  0.362
2015 Reniere ML, Whiteley AT, Hamilton KL, John SM, Lauer P, Brennan RG, Portnoy DA. Glutathione activates virulence gene expression of an intracellular pathogen. Nature. 517: 170-3. PMID 25567281 DOI: 10.1038/Nature14029  0.748
2015 Durack J, Burke TP, Portnoy DA. A prl mutation in SecY suppresses secretion and virulence defects of Listeria monocytogenes secA2 mutants. Journal of Bacteriology. 197: 932-42. PMID 25535272 DOI: 10.1128/JB.02284-14  0.318
2015 Kline BC, McKay SL, Tang WW, Portnoy DA. The Listeria monocytogenes hibernation-promoting factor is required for the formation of 100S ribosomes, optimal fitness, and pathogenesis. Journal of Bacteriology. 197: 581-91. PMID 25422304 DOI: 10.1128/Jb.02223-14  0.667
2014 Burke TP, Loukitcheva A, Zemansky J, Wheeler R, Boneca IG, Portnoy DA. Listeria monocytogenes is resistant to lysozyme through the regulation, not the acquisition, of cell wall-modifying enzymes. Journal of Bacteriology. 196: 3756-67. PMID 25157076 DOI: 10.1128/Jb.02053-14  0.324
2014 Archer KA, Durack J, Portnoy DA. STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes. Plos Pathogens. 10: e1003861. PMID 24391507 DOI: 10.1371/Journal.Ppat.1003861  0.434
2013 Witte CE, Whiteley AT, Burke TP, Sauer JD, Portnoy DA, Woodward JJ. Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection. Mbio. 4: e00282-13. PMID 23716572 DOI: 10.1128/Mbio.00282-13  0.635
2013 Leong M, Kanne D, Glickman L, Lemmens E, Lauer P, Metchette K, Burdette D, Diner E, Fu J, Soares K, Brockstedt D, Portnoy D, Vance R, Kim Y, Jaffee E, et al. Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines Journal For Immunotherapy of Cancer. 1: O20. DOI: 10.1186/2051-1426-1-S1-O20  0.457
2012 Melton-Witt JA, McKay SL, Portnoy DA. Development of a single-gene, signature-tag-based approach in combination with alanine mutagenesis to identify listeriolysin O residues critical for the in vivo survival of Listeria monocytogenes. Infection and Immunity. 80: 2221-30. PMID 22451517 DOI: 10.1128/IAI.06196-11  0.34
2012 Schwartz KT, Carleton JD, Quillin SJ, Rollins SD, Portnoy DA, Leber JH. Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT. Infection and Immunity. 80: 1537-45. PMID 22290148 DOI: 10.1128/IAI.06286-11  0.434
2012 Witte CE, Archer KA, Rae CS, Sauer JD, Woodward JJ, Portnoy DA. Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity. Advances in Immunology. 113: 135-56. PMID 22244582 DOI: 10.1016/B978-0-12-394590-7.00002-6  0.665
2011 Rae CS, Geissler A, Adamson PC, Portnoy DA. Mutations of the Listeria monocytogenes peptidoglycan N-deacetylase and O-acetylase result in enhanced lysozyme sensitivity, bacteriolysis, and hyperinduction of innate immune pathways. Infection and Immunity. 79: 3596-606. PMID 21768286 DOI: 10.1128/Iai.00077-11  0.768
2011 Sauer JD, Pereyre S, Archer KA, Burke TP, Hanson B, Lauer P, Portnoy DA. Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity. Proceedings of the National Academy of Sciences of the United States of America. 108: 12419-24. PMID 21746921 DOI: 10.1073/Pnas.1019041108  0.781
2011 Waite JC, Leiner I, Lauer P, Rae CS, Barbet G, Zheng H, Portnoy DA, Pamer EG, Dustin ML. Dynamic imaging of the effector immune response to listeria infection in vivo. Plos Pathogens. 7: e1001326. PMID 21455492 DOI: 10.1371/Journal.Ppat.1001326  0.707
2011 Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infection and Immunity. 79: 688-94. PMID 21098106 DOI: 10.1128/Iai.00999-10  0.635
2010 Woodward JJ, Iavarone AT, Portnoy DA. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science (New York, N.Y.). 328: 1703-5. PMID 20508090 DOI: 10.1126/Science.1189801  0.436
2010 Sauer JD, Witte CE, Zemansky J, Hanson B, Lauer P, Portnoy DA. Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host & Microbe. 7: 412-9. PMID 20417169 DOI: 10.1016/J.Chom.2010.04.004  0.787
2010 Meyer-Morse N, Robbins JR, Rae CS, Mochegova SN, Swanson MS, Zhao Z, Virgin HW, Portnoy D. Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection. Plos One. 5: e8610. PMID 20062534 DOI: 10.1371/Journal.Pone.0008610  0.804
2009 Bahjat KS, Meyer-Morse N, Lemmens EE, Shugart JA, Dubensky TW, Brockstedt DG, Portnoy DA. Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria. Plos Pathogens. 5: e1000568. PMID 19730694 DOI: 10.1371/Journal.Ppat.1000568  0.825
2009 Vance RE, Isberg RR, Portnoy DA. Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host & Microbe. 6: 10-21. PMID 19616762 DOI: 10.1016/J.Chom.2009.06.007  0.602
2009 Crimmins GT, Schelle MW, Herskovits AA, Ni PP, Kline BC, Meyer-Morse N, Iavarone AT, Portnoy DA. Listeria monocytogenes 6-Phosphogluconolactonase mutants induce increased activation of a host cytosolic surveillance pathway. Infection and Immunity. 77: 3014-22. PMID 19398547 DOI: 10.1128/Iai.01511-08  0.767
2009 Zemansky J, Kline BC, Woodward JJ, Leber JH, Marquis H, Portnoy DA. Development of a mariner-based transposon and identification of Listeria monocytogenes determinants, including the peptidyl-prolyl isomerase PrsA2, that contribute to its hemolytic phenotype. Journal of Bacteriology. 191: 3950-64. PMID 19376879 DOI: 10.1128/Jb.00016-09  0.708
2009 Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, Luckett W, Peterson JW, Calendar R, Portnoy DA, Lyons CR, Dubensky TW. Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax. Infection and Immunity. 77: 1649-63. PMID 19168734 DOI: 10.1128/Iai.00530-08  0.71
2008 Crimmins GT, Herskovits AA, Rehder K, Sivick KE, Lauer P, Dubensky TW, Portnoy DA. Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 10191-6. PMID 18632558 DOI: 10.1073/Pnas.0804170105  0.812
2008 Leber JH, Crimmins GT, Raghavan S, Meyer-Morse NP, Cox JS, Portnoy DA. Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. Plos Pathogens. 4: e6. PMID 18193943 DOI: 10.1371/Journal.Ppat.0040006  0.792
2008 Viala JP, Mochegova SN, Meyer-Morse N, Portnoy DA. A bacterial pore-forming toxin forms aggregates in cells that resemble those associated with neurodegenerative diseases. Cellular Microbiology. 10: 985-93. PMID 18067608 DOI: 10.1111/J.1462-5822.2007.01100.X  0.792
2007 Schnupf P, Portnoy DA. Listeriolysin O: a phagosome-specific lysin. Microbes and Infection / Institut Pasteur. 9: 1176-87. PMID 17720603 DOI: 10.1016/j.micinf.2007.05.005  0.335
2007 Schnupf P, Zhou J, Varshavsky A, Portnoy DA. Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway. Infection and Immunity. 75: 5135-47. PMID 17682039 DOI: 10.1128/Iai.00164-07  0.358
2007 Herskovits AA, Auerbuch V, Portnoy DA. Bacterial ligands generated in a phagosome are targets of the cytosolic innate immune system. Plos Pathogens. 3: e51. PMID 17397264 DOI: 10.1371/Journal.Ppat.0030051  0.769
2007 Portnoy DA. A 20-year perspective on listeria monocytogenes pathogenesis Listeria Monocytogenes: Pathogenesis and Host Response. 1-12. DOI: 10.1007/978-0-387-49376-3-1  0.32
2006 Bahjat KS, Liu W, Lemmens EE, Schoenberger SP, Portnoy DA, Dubensky TW, Brockstedt DG. Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infection and Immunity. 74: 6387-97. PMID 16954391 DOI: 10.1128/Iai.01088-06  0.34
2006 Schnupf P, Portnoy DA, Decatur AL. Phosphorylation, ubiquitination and degradation of listeriolysin O in mammalian cells: role of the PEST-like sequence. Cellular Microbiology. 8: 353-64. PMID 16441444 DOI: 10.1111/j.1462-5822.2005.00631.x  0.388
2005 Cheng LW, Viala JP, Stuurman N, Wiedemann U, Vale RD, Portnoy DA. Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proceedings of the National Academy of Sciences of the United States of America. 102: 13646-51. PMID 16157870 DOI: 10.1073/Pnas.0506461102  0.32
2005 Bakardjiev AI, Stacy BA, Portnoy DA. Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection. The Journal of Infectious Diseases. 191: 1889-97. PMID 15871123 DOI: 10.1086/430090  0.304
2005 Portnoy DA. Manipulation of innate immunity by bacterial pathogens. Current Opinion in Immunology. 17: 25-8. PMID 15653306 DOI: 10.1016/j.coi.2004.11.002  0.346
2004 Brockstedt DG, Giedlin MA, Leong ML, Bahjat KS, Gao Y, Luckett W, Liu W, Cook DN, Portnoy DA, Dubensky TW. Listeria-based cancer vaccines that segregate immunogenicity from toxicity. Proceedings of the National Academy of Sciences of the United States of America. 101: 13832-7. PMID 15365184 DOI: 10.1073/Pnas.0406035101  0.307
2004 Auerbuch V, Brockstedt DG, Meyer-Morse N, O'Riordan M, Portnoy DA. Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. The Journal of Experimental Medicine. 200: 527-33. PMID 15302899 DOI: 10.1084/Jem.20040976  0.784
2004 McCaffrey RL, Fawcett P, O'Riordan M, Lee KD, Havell EA, Brown PO, Portnoy DA. A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proceedings of the National Academy of Sciences of the United States of America. 101: 11386-91. PMID 15269347 DOI: 10.1073/Pnas.0403215101  0.366
2003 Cheng LW, Portnoy DA. Drosophila S2 cells: an alternative infection model for Listeria monocytogenes. Cellular Microbiology. 5: 875-85. PMID 14641173 DOI: 10.1046/j.1462-5822.2003.00327.x  0.392
2003 Glomski IJ, Decatur AL, Portnoy DA. Listeria monocytogenes mutants that fail to compartmentalize listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infection and Immunity. 71: 6754-65. PMID 14638761 DOI: 10.1128/IAI.71.12.6754-6765.2003  0.787
2003 O'Riordan M, Moors MA, Portnoy DA. Listeria intracellular growth and virulence require host-derived lipoic acid. Science (New York, N.Y.). 302: 462-4. PMID 14564012 DOI: 10.1126/Science.1088170  0.364
2003 Lenz LL, Mohammadi S, Geissler A, Portnoy DA. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12432-7. PMID 14527997 DOI: 10.1073/Pnas.2133653100  0.777
2003 Auerbuch V, Loureiro JJ, Gertler FB, Theriot JA, Portnoy DA. Ena/VASP proteins contribute to Listeria monocytogenes pathogenesis by controlling temporal and spatial persistence of bacterial actin-based motility. Molecular Microbiology. 49: 1361-75. PMID 12940993 DOI: 10.1046/J.1365-2958.2003.03639.X  0.735
2002 Dancz CE, Haraga A, Portnoy DA, Higgins DE. Inducible control of virulence gene expression in Listeria monocytogenes: temporal requirement of listeriolysin O during intracellular infection. Journal of Bacteriology. 184: 5935-45. PMID 12374827 DOI: 10.1128/Jb.184.21.5935-5945.2002  0.709
2002 O'Riordan M, Yi CH, Gonzales R, Lee KD, Portnoy DA. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 13861-6. PMID 12359878 DOI: 10.1073/Pnas.202476699  0.812
2002 Portnoy DA, Auerbuch V, Glomski IJ. The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. The Journal of Cell Biology. 158: 409-14. PMID 12163465 DOI: 10.1083/Jcb.200205009  0.828
2002 O'Riordan M, Portnoy DA. The host cytosol: front-line or home front? Trends in Microbiology. 10: 361-4. PMID 12160633 DOI: 10.1016/S0966-842X(02)02401-0  0.36
2002 Lauer P, Chow MY, Loessner MJ, Portnoy DA, Calendar R. Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors. Journal of Bacteriology. 184: 4177-86. PMID 12107135 DOI: 10.1128/Jb.184.15.4177-4186.2002  0.661
2002 Auerbuch V, Portnoy DA. Microbial pathogenesis and the eukaryotic cytoskeleton at the American Society for Cell Biology annual meeting. Cellular Microbiology. 4: 187-90. PMID 11906455 DOI: 10.1046/J.1462-5822.2002.00187.X  0.687
2002 Glomski IJ, Gedde MM, Tsang AW, Swanson JA, Portnoy DA. The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. The Journal of Cell Biology. 156: 1029-38. PMID 11901168 DOI: 10.1083/Jcb.200201081  0.755
2002 O'Riordan M, Portnoy DA. Bacterial growth in the cytosol: lessons from Listeria Trends in Microbiology. 10: 495. DOI: 10.1016/S0966-842X(02)02453-8  0.421
2001 Lauer P, Theriot JA, Skoble J, Welch MD, Portnoy DA. Systematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility. Molecular Microbiology. 42: 1163-77. PMID 11886549 DOI: 10.1046/J.1365-2958.2001.02677.X  0.786
2001 Skoble J, Auerbuch V, Goley ED, Welch MD, Portnoy DA. Pivotal role of VASP in Arp2/3 complex-mediated actin nucleation, actin branch-formation, and Listeria monocytogenes motility. The Journal of Cell Biology. 155: 89-100. PMID 11581288 DOI: 10.1083/Jcb.200106061  0.769
2001 Auerbuch V, Lenz LL, Portnoy DA. Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice. Infection and Immunity. 69: 5953-7. PMID 11500481 DOI: 10.1128/Iai.69.9.5953-5957.2001  0.714
2000 Skoble J, Portnoy DA, Welch MD. Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility. The Journal of Cell Biology. 150: 527-38. PMID 10931865 DOI: 10.1083/Jcb.150.3.527  0.753
2000 Gedde MM, Higgins DE, Tilney LG, Portnoy DA. Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes. Infection and Immunity. 68: 999-1003. PMID 10639481 DOI: 10.1128/Iai.68.2.999-1003.2000  0.705
1999 Moors MA, Auerbuch V, Portnoy DA. Stability of the Listeria monocytogenes ActA protein in mammalian cells is regulated by the N-end rule pathway. Cellular Microbiology. 1: 249-57. PMID 11207557 DOI: 10.1046/J.1462-5822.1999.00020.X  0.736
1999 Higgins DE, Shastri N, Portnoy DA. Delivery of protein to the cytosol of macrophages using Escherichia coli K-12 Molecular Microbiology. 31: 1631-1641. PMID 10209738 DOI: 10.1046/J.1365-2958.1999.01272.X  0.641
1999 Moors MA, Levitt B, Youngman P, Portnoy DA. Expression of listeriolysin O and ActA by intracellular and extracellular Listeria monocytogenes Infection and Immunity. 67: 131-139. PMID 9864207  0.333
1998 Thompson RJ, Bouwer HG, Portnoy DA, Frankel FR. Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires D-alanine for growth. Infection and Immunity. 66: 3552-61. PMID 9673233  0.39
1998 Welch MD, Rosenblatt J, Skoble J, Portnoy DA, Mitchison TJ. Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. Science (New York, N.Y.). 281: 105-8. PMID 9651243 DOI: 10.1126/Science.281.5373.105  0.743
1998 Higgins DE, Portnoy DA. Bacterial delivery of DNA evolves Nature Biotechnology. 16: 138-139. PMID 9487514 DOI: 10.1038/Nbt0298-138  0.593
1997 Marquis H, Goldfine H, Portnoy DA. Proteolytic pathways of activation and degradation of a bacterial phospholipase C during intracellular infection by Listeria monocytogenes Journal of Cell Biology. 137: 1381-1392. PMID 9182669 DOI: 10.1083/jcb.137.6.1381  0.38
1996 Jones S, Preiter K, Portnoy DA. Conversion of an extracellular cytolysin into a phagosome-specific lysin which supports the growth of an intracellular pathogen Molecular Microbiology. 21: 1219-1225. PMID 8898390  0.427
1995 Marquis H, Doshi V, Portnoy DA. The broad-range phospholipase C and a metalloprotease mediate listeriolysin O-independent escape of Listeria monocytogenes from a primary vacuole in human epithelial cells Infection and Immunity. 63: 4531-4534. PMID 7591098  0.335
1995 Smith GA, Marquis H, Jones S, Johnston NC, Portnoy DA, Goldfine H. The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread Infection and Immunity. 63: 4231-4237. PMID 7591052  0.349
1994 Theriot JA, Rosenblatt J, Portnoy DA, Goldschmidt-Clermont PJ, Mitchison TJ. Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell. 76: 505-17. PMID 8313471 DOI: 10.1016/0092-8674(94)90114-7  0.393
1994 Portnoy DA, Smith GA, Goldfine H. Phospholipases C and the pathogenesis of Listeria Brazilian Journal of Medical and Biological Research. 27: 357-361. PMID 8081249  0.362
1994 Freitag NE, Portnoy DA. Dual promoters of the Listeria monocytogenes prfA transcriptional activator appear essential in vitro but are redundant in vivo Molecular Microbiology. 12: 845-853. PMID 8052135 DOI: 10.1111/j.1365-2958.1994.tb01070.x  0.312
1994 Andrews NW, Portnoy DA. Cytolysins from intracellular pathogens Trends in Microbiology. 2: 261-263. PMID 7981967 DOI: 10.1016/0966-842X(94)90001-9  0.346
1994 Jones S, Portnoy DA. Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O Infection and Immunity. 62: 5608-5613. PMID 7960143  0.332
1993 Camilli A, Tilney LG, Portnoy DA. Dual roles of plcA in Listeria monocytogenes pathogenesis. Molecular Microbiology. 8: 143-57. PMID 8388529 DOI: 10.1111/j.1365-2958.1993.tb01211.x  0.31
1993 Brundage RA, Smith GA, Camilli A, Theriot JA, Portnoy DA. Expression and phosphorylation of the Listeria monocytogenes actA protein in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 90: 11890-11894. PMID 8265643  0.342
1992 Portnoy DA. Innate immunity to a facultative intracellular bacterial pathogen. Current Opinion in Immunology. 4: 20-4. PMID 1596365 DOI: 10.1016/0952-7915(92)90118-X  0.383
1992 Bouwer HG, Nelson CS, Gibbins BL, Portnoy DA, Hinrichs DJ. Listeriolysin O is a target of the immune response to Listeria monocytogenes. The Journal of Experimental Medicine. 175: 1467-71. PMID 1588276 DOI: 10.1084/jem.175.6.1467  0.359
1992 Falkow S, Isberg RR, Portnoy DA. The interaction of bacteria with mammalian cells. Annual Review of Cell Biology. 8: 333-63. PMID 1476803 DOI: 10.1146/Annurev.Cb.08.110192.002001  0.67
1992 Barry RA, Bouwer HG, Portnoy DA, Hinrichs DJ. Pathogenicity and immunogenicity of Listeria monocytogenes small-plaque mutants defective for intracellular growth and cell-to-cell spread. Infection and Immunity. 60: 1625-1632. DOI: 10.1128/iai.60.4.1625-1632.1992  0.31
1992 Portnoy DA. Innate immunity to a facultative intracellular bacterial pathogen Current Biology. 2: 184. DOI: 10.1016/0960-9822(92)90511-8  0.343
1991 Camilli A, Goldfine H, Portnoy DA. Listeria monocytogenes mutants lacking phosphatidylinositol-specific phospholipase C are avirulent. The Journal of Experimental Medicine. 173: 751-4. PMID 1847723 DOI: 10.1084/jem.173.3.751  0.392
1990 Dabiri GA, Sanger JM, Portnoy DA, Southwick FS. Listeria monocytogenes moves rapidly through the host-cell cytoplasm by inducing directional actin assembly. Proceedings of the National Academy of Sciences of the United States of America. 87: 6068-72. PMID 2117270 DOI: 10.1073/Pnas.87.16.6068  0.318
1990 Bielecki J, Youngman P, Connelly P, Portnoy DA. Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells Nature. 345: 175-176. PMID 2110628 DOI: 10.1038/345175a0  0.387
1989 Portnoy DA, Schreiber RD, Connelly P, Tilney LG. Gamma interferon limits access of Listeria monocytogenes to the macrophage cytoplasm. The Journal of Experimental Medicine. 170: 2141-6. PMID 2511268 DOI: 10.1084/jem.170.6.2141  0.319
1989 Tilney LG, Portnoy DA. Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes. The Journal of Cell Biology. 109: 1597-608. PMID 2507553 DOI: 10.1083/jcb.109.4.1597  0.332
1985 Wolf-Watz H, Portnoy DA, Bölin I, Falkow S. Transfer of the virulence plasmid of Yersinia pestis to Yersinia pseudotuberculosis. Infection and Immunity. 48: 241-3. PMID 3884511 DOI: 10.1128/Iai.48.1.241-243.1985  0.442
1984 Portnoy DA, Wolf-Watz H, Bolin I, Beeder AB, Falkow S. Characterization of common virulence plasmids in Yersinia species and their role in the expression of outer membrane proteins. Infection and Immunity. 43: 108-14. PMID 6317562 DOI: 10.1128/Iai.43.1.108-114.1984  0.444
1983 Portnoy DA, Blank HF, Kingsbury DT, Falkow S. Genetic analysis of essential plasmid determinants of pathogenicity in Yersinia pestis. The Journal of Infectious Diseases. 148: 297-304. PMID 6310003  0.454
1981 Portnoy DA, Falkow S. Virulence-associated plasmids from Yersinia enterocolitica and Yersinia pestis. Journal of Bacteriology. 148: 877-883. DOI: 10.1128/Jb.148.3.877-883.1981  0.432
1981 Helmuth R, Stephan R, Bulling E, van Leeuwen WJ, van Embden JD, Guinée PA, Portnoy D, Falkow S. R-factor cointegrate formation in Salmonella typhimurium bacteriophage type 201 strains. Journal of Bacteriology. 146: 444-452. DOI: 10.1128/Jb.146.2.444-452.1981  0.512
1981 Portnoy DA, Moseley SL, Falkow S. Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis. Infection and Immunity. 31: 775-782. DOI: 10.1128/iai.31.2.775-782.1981  0.425
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