| Year |
Citation |
Score |
| 2023 |
Van Loh BM, Yaw AM, Breuer JA, Jackson B, Nguyen D, Jang K, Ramos F, Ho EV, Cui LJ, Gillette DLM, Sempere LF, Gorman MR, Tonsfeldt KJ, Mellon PL, Hoffmann HM. The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice. Frontiers in Endocrinology. 14: 1269672. PMID 38205198 DOI: 10.3389/fendo.2023.1269672 |
0.743 |
|
| 2023 |
Cassin J, Stamou MI, Keefe KW, Sung K, Bojo C, Tonsfeldt KJ, Rojas RA, Ferreira Lopes V, Plummer L, Salnikov KB, Keefe DL, Ozata M, Genel M, Georgopoulos NA, Hall JE, ... ... Mellon PL, et al. Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms. Jci Insight. PMID 36602867 DOI: 10.1172/jci.insight.164324 |
0.714 |
|
| 2022 |
Tonsfeldt KJ, Cui LJ, Lee J, Walbeek TJ, Brusman LE, Jin Y, Mieda M, Gorman MR, Mellon PL. Female fertility does not require in suprachiasmatic nucleus neurons expressing arginine vasopressin, vasoactive intestinal peptide, or neuromedin-S. Frontiers in Endocrinology. 13: 956169. PMID 35992114 DOI: 10.3389/fendo.2022.956169 |
0.746 |
|
| 2022 |
Lavalle SN, Chou T, Hernandez J, Naing NCP, He MY, Tonsfeldt KJ, Mellon PL. Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice. Molecular and Cellular Endocrinology. 546: 111577. PMID 35121076 DOI: 10.1016/j.mce.2022.111577 |
0.741 |
|
| 2021 |
Tonsfeldt KJ, Mellon PL, Hoffmann HM. Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge. Endocrinology. PMID 34967900 DOI: 10.1210/endocr/bqab268 |
0.689 |
|
| 2021 |
Ho EV, Shi C, Cassin J, He MY, Nguyen RD, Ryan GE, Tonsfeldt KJ, Mellon PL. Reproductive Deficits Induced by Prenatal Anti-Mullerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells. Endocrinology. PMID 34529765 DOI: 10.1210/endocr/bqab197 |
0.734 |
|
| 2021 |
Hoffmann HM, Meadows JD, Breuer JA, Yaw AM, Nguyen D, Tonsfeldt KJ, Chin AY, Devries BM, Trang C, Oosterhouse HJ, Lee JS, Doser JW, Gorman MR, Welsh DK, Mellon PL. The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. Journal of Neuroscience Research. PMID 34212416 DOI: 10.1002/jnr.24864 |
0.759 |
|
| 2021 |
Lavalle SN, Chou T, Hernandez J, Naing NCP, Tonsfeldt KJ, Hoffmann HM, Mellon PL. Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1. Molecular and Cellular Endocrinology. 111358. PMID 34098016 DOI: 10.1016/j.mce.2021.111358 |
0.781 |
|
| 2021 |
Ryan GE, Bohaczuk SC, Cassin J, Witham EA, Shojaei S, Ho EV, Thackray VG, Mellon PL. Androgen receptor positively regulates gonadotropin-releasing hormone receptor in pituitary gonadotropes. Molecular and Cellular Endocrinology. 530: 111286. PMID 33872733 DOI: 10.1016/j.mce.2021.111286 |
0.833 |
|
| 2021 |
Bohaczuk SC, Cassin J, Slaiwa TI, Thackray VG, Mellon PL. Distal Enhancer Potentiates Activin- and GnRH-Induced Transcription of FSHB. Endocrinology. PMID 33824966 DOI: 10.1210/endocr/bqab069 |
0.45 |
|
| 2021 |
Schoeller EL, Tonsfeldt KJ, Sinkovich M, Shi R, Mellon PL. Growth Hormone Pulses and Liver Gene Expression are Differentially Regulated by the Circadian Clock Gene Bmal1. Endocrinology. PMID 33539533 DOI: 10.1210/endocr/bqab023 |
0.745 |
|
| 2020 |
Bohaczuk SC, Thackray VG, Shen J, Skowronska-Krawczyk D, Mellon PL. FSHB Transcription is Regulated by a Novel 5' Distal Enhancer with a Fertility-Associated Single Nucleotide Polymorphism. Endocrinology. PMID 33009549 DOI: 10.1210/endocr/bqaa181 |
0.439 |
|
| 2020 |
Nicholas DA, Knight VS, Tonsfeldt KJ, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Scientific Reports. 10: 13063. PMID 32747664 DOI: 10.1038/S41598-020-69913-Z |
0.77 |
|
| 2020 |
Lavalle SN, Hernandez J, Mellon PL. OR16-01 The Expression of the Homeodomain Transcription Factor SIX3 within Kisspeptin Neurons Is Necessary for Reproduction in Mice Journal of the Endocrine Society. 4. DOI: 10.1210/jendso/bvaa046.965 |
0.316 |
|
| 2020 |
Bohaczuk SC, Thackray VG, Mellon PL. OR24-05 Identifying Regulatory Elements Within a Novel Enhancer of FSHB Containing Two PCOS-Associated Single Nucleotide Polymorphisms Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.749 |
0.316 |
|
| 2020 |
Nicholas D, Knight V, Tonsfeldt K, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. MON-009 GLUT1-Mediated Glycolysis Facilitates GnRH-Induced Secretion of Luteinizing Hormone Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1694 |
0.734 |
|
| 2019 |
Pandolfi EC, Breuer JA, Nguyen Huu VA, Talluri T, Nguyen D, Lee JS, Hu R, Bharti K, Skowronska-Krawczyk D, Gorman MR, Mellon PL, Hoffmann HM. The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function. Molecular Neurobiology. PMID 31705443 DOI: 10.1007/s12035-019-01781-9 |
0.426 |
|
| 2019 |
Pandolfi EC, Tonsfeldt KJ, Hoffmann HM, Mellon PL. Deletion of the Homeodomain Protein Six6 from GnRH Neurons Decreases GnRH Gene Expression Resulting in Infertility. Endocrinology. PMID 31211355 DOI: 10.1210/En.2019-00113 |
0.747 |
|
| 2019 |
Tonsfeldt KJ, Schoeller EL, Brusman LE, Cui LJ, Lee J, Mellon PL. The Contribution of the Circadian Gene to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge. Journal of the Endocrine Society. 3: 716-733. PMID 30906911 DOI: 10.1210/Js.2018-00228 |
0.784 |
|
| 2019 |
Hoffmann HM, Larder R, Lee J, Hu R, Trang C, Devries B, Clark D, Mellon PL. Differential CRE expression in Lhrh-Cre and Gnrh-Cre alleles and the impact on fertility in Otx2-flox mice. Neuroendocrinology. PMID 30739114 DOI: 10.1159/000497791 |
0.469 |
|
| 2019 |
Tonsfeldt K, Cui L, Mellon P. SUN-473 The Contribution of Bmal1 Expression in the Suprachiasmatic Nucleus to Female Fertility Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-473 |
0.725 |
|
| 2019 |
Newton S, Mellon P. SUN-470 The Homeodomain Transcription Factors Six3 and OTX2 Act on Mouse and Human Kisspeptin Promoters to Repress Transcription Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-470 |
0.4 |
|
| 2019 |
Nicholas D, Knight V, Terasaka T, Choi Ji, Muñoz O, Mellon P, Lawson M. SAT-177 GLUT1-Mediated Glucose Metabolism Is Necessary for GnRH-Induced Gonadotrope Secretion of LH and Is Increased by Androgen Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-177 |
0.331 |
|
| 2019 |
Bohaczuk S, Thackray V, Mellon P. OR15-2 A Novel Upstream Enhancer Acts Synergistically with GnRH and Activin to Increase FSHβ Transcription Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or15-2 |
0.476 |
|
| 2018 |
Hoffmann H, Pandolfi E, Larder R, Mellon P. Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2, Causes Subfertility in Mice Via Distinct Mechanisms. Neuroendocrinology. PMID 30261489 DOI: 10.1159/000494086 |
0.355 |
|
| 2018 |
Pandolfi EC, Hoffmann HM, Schoeller EL, Gorman MR, Mellon PL. Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration. Molecular Neurobiology. PMID 29589282 DOI: 10.1007/s12035-018-1013-0 |
0.313 |
|
| 2018 |
Ryan GE, Malik S, Mellon PL. Antiandrogen treatment ameliorates reproductive and metabolic phenotypes in the letrozole-induced mouse model of PCOS. Endocrinology. PMID 29471436 DOI: 10.1210/en.2017-03218 |
0.324 |
|
| 2017 |
Xie H, Hoffmann HM, Iyer AK, Brayman MJ, Ngo C, Sunshine MJ, Mellon PL. Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. Reproductive Biology and Endocrinology : Rb&E. 15: 86. PMID 29065928 DOI: 10.1186/s12958-017-0304-z |
0.44 |
|
| 2017 |
Hoffmann HM, Gong P, Tamrazian A, Mellon PL. Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Molecular and Cellular Endocrinology. PMID 28890143 DOI: 10.1016/j.mce.2017.09.004 |
0.539 |
|
| 2016 |
Hoffmann HM, Mellon PL. A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. Neuroscience Communications. 2. PMID 28164172 |
0.449 |
|
| 2016 |
Huang PP, Brusman LE, Iyer AK, Webster NJ, Mellon PL. A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models. Plos One. 11: e0158597. PMID 27389022 DOI: 10.1371/Journal.Pone.0158597 |
0.378 |
|
| 2016 |
Hoffmann HM, Trang C, Gong P, Kimura I, Pandolfi EC, Mellon PL. Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3506-18. PMID 27013679 DOI: 10.1523/JNEUROSCI.2723-15.2016 |
0.452 |
|
| 2015 |
Stephens SB, Tolson KP, Rouse ML, Poling MC, Hashimoto-Partyka MK, Mellon PL, Kauffman AS. Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice. Endocrinology. en20151300. PMID 26076042 DOI: 10.1210/en.2015-1300 |
0.38 |
|
| 2015 |
Xie H, Hoffmann HM, Meadows JD, Mayo SL, Trang C, Leming SS, Maruggi C, Davis SW, Larder R, Mellon PL. Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development. Molecular Endocrinology (Baltimore, Md.). 29: 842-55. PMID 25915183 DOI: 10.1210/me.2014-1279 |
0.53 |
|
| 2014 |
Roybal LL, Hambarchyan A, Meadows JD, Barakat NH, Pepa PA, Breen KM, Mellon PL, Coss D. Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ. Molecular Endocrinology (Baltimore, Md.). 28: 1640-55. PMID 25105693 DOI: 10.1210/Me.2014-1008 |
0.771 |
|
| 2014 |
Hoffmann HM, Tamrazian A, Xie H, Pérez-Millán MI, Kauffman AS, Mellon PL. Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology. 155: 4043-53. PMID 25060364 DOI: 10.1210/en.2014-1277 |
0.424 |
|
| 2014 |
Glidewell-Kenney CA, Trang C, Shao PP, Gutierrez-Reed N, Uzo-Okereke AM, Coss D, Mellon PL. Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons. Endocrinology. 155: 3909-19. PMID 25057795 DOI: 10.1210/En.2014-1263 |
0.735 |
|
| 2013 |
Larder R, Kimura I, Meadows J, Clark DD, Mayo S, Mellon PL. Gene dosage of Otx2 is important for fertility in male mice. Molecular and Cellular Endocrinology. 377: 16-22. PMID 23811236 DOI: 10.1016/j.mce.2013.06.026 |
0.44 |
|
| 2013 |
Witham EA, Meadows JD, Hoffmann HM, Shojaei S, Coss D, Kauffman AS, Mellon PL. Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes. Molecular Endocrinology (Baltimore, Md.). 27: 1283-94. PMID 23770611 DOI: 10.1210/Me.2012-1405 |
0.841 |
|
| 2013 |
Glidewell-Kenney CA, Shao PP, Iyer AK, Grove AM, Meadows JD, Mellon PL. Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Molecular Endocrinology (Baltimore, Md.). 27: 437-54. PMID 23393128 DOI: 10.1210/Me.2012-1271 |
0.511 |
|
| 2013 |
Xie H, Cherrington BD, Meadows JD, Witham EA, Mellon PL. Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development. Molecular Endocrinology (Baltimore, Md.). 27: 422-36. PMID 23371388 DOI: 10.1210/Me.2012-1289 |
0.85 |
|
| 2012 |
Brayman MJ, Pepa PA, Mellon PL. Androgen receptor repression of gonadotropin-releasing hormone gene transcription via enhancer 1. Molecular and Cellular Endocrinology. 363: 92-9. PMID 22877652 DOI: 10.1016/J.Mce.2012.07.012 |
0.46 |
|
| 2012 |
Breen KM, Thackray VG, Hsu T, Mak-McCully RA, Coss D, Mellon PL. Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. Molecular Endocrinology (Baltimore, Md.). 26: 1716-31. PMID 22851703 DOI: 10.1210/Me.2011-1327 |
0.76 |
|
| 2012 |
Witham EA, Meadows JD, Shojaei S, Kauffman AS, Mellon PL. Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice. Endocrinology. 153: 4522-32. PMID 22778229 DOI: 10.1210/En.2012-1283 |
0.795 |
|
| 2012 |
Ghochani Y, Saini JK, Mellon PL, Thackray VG. FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone β-subunit promoter. Endocrinology. 153: 2023-33. PMID 22294749 DOI: 10.1210/En.2011-1763 |
0.478 |
|
| 2012 |
Brayman MJ, Pepa PA, Berdy SE, Mellon PL. Androgen receptor repression of GnRH gene transcription. Molecular Endocrinology (Baltimore, Md.). 26: 2-13. PMID 22074952 DOI: 10.1210/Me.2011-1015 |
0.431 |
|
| 2011 |
Lan D, Lu M, Sharma S, Mellon PL, Olefsky JM, Webster NJ. Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHβ gene expression by a SirT1-independent pathway in LβT2 gonadotrope cells. Reproductive Toxicology (Elmsford, N.Y.). 32: 85-92. PMID 21679764 DOI: 10.1016/J.Reprotox.2011.05.006 |
0.448 |
|
| 2011 |
Yueh MF, Mellon PL, Tukey RH. Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor. Molecular Pharmacology. 79: 1053-60. PMID 21415305 DOI: 10.1124/Mol.110.070649 |
0.382 |
|
| 2011 |
Ely HA, Mellon PL, Coss D. GnRH induces the c-Fos gene via phosphorylation of SRF by the calcium/calmodulin kinase II pathway. Molecular Endocrinology (Baltimore, Md.). 25: 669-80. PMID 21292826 DOI: 10.1210/Me.2010-0437 |
0.745 |
|
| 2011 |
Iyer AK, Brayman MJ, Mellon PL. Dynamic chromatin modifications control GnRH gene expression during neuronal differentiation and protein kinase C signal transduction. Molecular Endocrinology (Baltimore, Md.). 25: 460-73. PMID 21239613 DOI: 10.1210/Edrv.32.1.Zef154B |
0.405 |
|
| 2011 |
Larder R, Clark DD, Miller NL, Mellon PL. Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 426-38. PMID 21228153 DOI: 10.1523/JNEUROSCI.1688-10.2011 |
0.706 |
|
| 2011 |
Sharma S, Sharma PM, Mistry DS, Chang RJ, Olefsky JM, Mellon PL, Webster NJ. PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biology of Reproduction. 84: 466-75. PMID 21076077 DOI: 10.1095/Biolreprod.110.088005 |
0.456 |
|
| 2010 |
Iyer AK, Miller NL, Yip K, Tran BH, Mellon PL. Enhancers of GnRH transcription embedded in an upstream gene use homeodomain proteins to specify hypothalamic expression. Molecular Endocrinology (Baltimore, Md.). 24: 1949-64. PMID 20667983 DOI: 10.1210/Me.2010-0156 |
0.671 |
|
| 2010 |
Coss D, Mellon PL, Thackray VG. A FoxL in the Smad house: activin regulation of FSH. Trends in Endocrinology and Metabolism: Tem. 21: 562-8. PMID 20598900 DOI: 10.1016/J.Tem.2010.05.006 |
0.763 |
|
| 2010 |
Breen KM, Thackray VG, Coss D, Mellon PL. Runt-related transcription factors impair activin induction of the follicle-stimulating hormone {beta}-subunit gene. Endocrinology. 151: 2669-80. PMID 20357224 DOI: 10.1210/En.2009-0949 |
0.805 |
|
| 2010 |
Corpuz PS, Lindaman LL, Mellon PL, Coss D. FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes. Molecular Endocrinology (Baltimore, Md.). 24: 1037-51. PMID 20233786 DOI: 10.1210/Me.2009-0425 |
0.769 |
|
| 2010 |
Thackray VG, Mellon PL, Coss D. Hormones in synergy: regulation of the pituitary gonadotropin genes. Molecular and Cellular Endocrinology. 314: 192-203. PMID 19747958 DOI: 10.1016/J.Mce.2009.09.003 |
0.77 |
|
| 2009 |
Larder R, Mellon PL. Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors. The Journal of Biological Chemistry. 284: 16966-78. PMID 19401468 DOI: 10.1074/jbc.M109.002485 |
0.515 |
|
| 2009 |
Thackray VG, Hunnicutt JL, Memon AK, Ghochani Y, Mellon PL. Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression. Endocrinology. 150: 2395-403. PMID 19106225 DOI: 10.1210/En.2008-1027 |
0.556 |
|
| 2009 |
Miller NL, Wevrick R, Mellon PL. Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Human Molecular Genetics. 18: 248-60. PMID 18930956 DOI: 10.1093/hmg/ddn344 |
0.706 |
|
| 2009 |
Avelino-Cruz JE, Flores A, Cebada J, Mellon PL, Felix R, Monjaraz E. Leptin increases L-type Ca2+ channel expression and GnRH-stimulated LH release in LbetaT2 gonadotropes. Molecular and Cellular Endocrinology. 298: 57-65. PMID 18834922 DOI: 10.1016/j.mce.2008.09.003 |
0.367 |
|
| 2008 |
Cherrington BD, Bailey JS, Diaz AL, Mellon PL. NeuroD1 and Mash1 temporally regulate GnRH receptor gene expression in immortalized mouse gonadotrope cells. Molecular and Cellular Endocrinology. 295: 106-14. PMID 18760324 DOI: 10.1016/J.Mce.2008.07.017 |
0.432 |
|
| 2008 |
Sasson R, Luu SH, Thackray VG, Mellon PL. Glucocorticoids induce human glycoprotein hormone alpha-subunit gene expression in the gonadotrope. Endocrinology. 149: 3643-55. PMID 18403486 DOI: 10.1210/En.2007-1100 |
0.511 |
|
| 2008 |
Thackray VG, Mellon PL. Synergistic induction of follicle-stimulating hormone beta-subunit gene expression by gonadal steroid hormone receptors and Smad proteins. Endocrinology. 149: 1091-102. PMID 18079204 DOI: 10.1210/En.2007-1498 |
0.484 |
|
| 2008 |
Lu M, Tang Q, Olefsky JM, Mellon PL, Webster NJ. Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes. Molecular Endocrinology (Baltimore, Md.). 22: 760-71. PMID 18006641 DOI: 10.1210/Me.2007-0330 |
0.422 |
|
| 2007 |
Coss D, Hand CM, Yaphockun KK, Ely HA, Mellon PL. p38 mitogen-activated protein kinase is critical for synergistic induction of the FSH(beta) gene by gonadotropin-releasing hormone and activin through augmentation of c-Fos induction and Smad phosphorylation. Molecular Endocrinology (Baltimore, Md.). 21: 3071-86. PMID 17823303 DOI: 10.1210/Me.2007-0247 |
0.734 |
|
| 2007 |
Lawson MA, Tsutsumi R, Zhang H, Talukdar I, Butler BK, Santos SJ, Mellon PL, Webster NJ. Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2. Molecular Endocrinology (Baltimore, Md.). 21: 1175-91. PMID 17299135 DOI: 10.1210/Me.2006-0392 |
0.361 |
|
| 2007 |
McGillivray SM, Thackray VG, Coss D, Mellon PL. Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line. Endocrinology. 148: 762-73. PMID 17082263 DOI: 10.1210/En.2006-0952 |
0.847 |
|
| 2006 |
Sasson R, Dearth RK, White RS, Chappell PE, Mellon PL. Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons. Neuroendocrinology. 84: 353-63. PMID 17192702 DOI: 10.1159/000098333 |
0.416 |
|
| 2006 |
Zhang H, Bailey JS, Coss D, Lin B, Tsutsumi R, Lawson MA, Mellon PL, Webster NJ. Activin modulates the transcriptional response of LbetaT2 cells to gonadotropin-releasing hormone and alters cellular proliferation. Molecular Endocrinology (Baltimore, Md.). 20: 2909-30. PMID 16772531 DOI: 10.1210/Me.2006-0109 |
0.782 |
|
| 2006 |
Thackray VG, McGillivray SM, Mellon PL. Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope. Molecular Endocrinology (Baltimore, Md.). 20: 2062-79. PMID 16675544 DOI: 10.1210/Me.2005-0316 |
0.815 |
|
| 2005 |
Rave-Harel N, Miller NL, Givens ML, Mellon PL. The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1. The Journal of Biological Chemistry. 280: 30975-83. PMID 16002402 DOI: 10.1074/Jbc.M502315200 |
0.842 |
|
| 2005 |
Tang Q, Mazur M, Mellon PL. The protein kinase C pathway acts through multiple transcription factors to repress gonadotropin-releasing hormone gene expression in hypothalamic GT1-7 neuronal cells. Molecular Endocrinology (Baltimore, Md.). 19: 2769-79. PMID 15994198 DOI: 10.1210/me.2004-0463 |
0.52 |
|
| 2005 |
Coss D, Thackray VG, Deng CX, Mellon PL. Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements. Molecular Endocrinology (Baltimore, Md.). 19: 2610-23. PMID 15961509 DOI: 10.1210/Me.2005-0047 |
0.793 |
|
| 2005 |
Givens ML, Rave-Harel N, Goonewardena VD, Kurotani R, Berdy SE, Swan CH, Rubenstein JL, Robert B, Mellon PL. Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families. The Journal of Biological Chemistry. 280: 19156-65. PMID 15743757 DOI: 10.1074/Jbc.M502004200 |
0.813 |
|
| 2005 |
McGillivray SM, Bailey JS, Ramezani R, Kirkwood BJ, Mellon PL. Mouse GnRH receptor gene expression is mediated by the LHX3 homeodomain protein. Endocrinology. 146: 2180-5. PMID 15705775 DOI: 10.1210/En.2004-1566 |
0.837 |
|
| 2004 |
Givens ML, Kurotani R, Rave-Harel N, Miller NL, Mellon PL. Phylogenetic footprinting reveals evolutionarily conserved regions of the gonadotropin-releasing hormone gene that enhance cell-specific expression. Molecular Endocrinology (Baltimore, Md.). 18: 2950-66. PMID 15319450 DOI: 10.1210/Me.2003-0437 |
0.84 |
|
| 2004 |
Rave-Harel N, Givens ML, Nelson SB, Duong HA, Coss D, Clark ME, Hall SB, Kamps MP, Mellon PL. TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1. The Journal of Biological Chemistry. 279: 30287-97. PMID 15138251 DOI: 10.1074/Jbc.M402960200 |
0.86 |
|
| 2004 |
Bailey JS, Rave-Harel N, McGillivray SM, Coss D, Mellon PL. Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1. Molecular Endocrinology (Baltimore, Md.). 18: 1158-70. PMID 14764653 DOI: 10.1210/Me.2003-0442 |
0.831 |
|
| 2004 |
Spady TJ, Shayya R, Thackray VG, Ehrensberger L, Bailey JS, Mellon PL. Androgen regulates follicle-stimulating hormone beta gene expression in an activin-dependent manner in immortalized gonadotropes. Molecular Endocrinology (Baltimore, Md.). 18: 925-40. PMID 14701939 DOI: 10.1210/Me.2003-0115 |
0.495 |
|
| 2004 |
Coss D, Jacobs SB, Bender CE, Mellon PL. A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone. The Journal of Biological Chemistry. 279: 152-62. PMID 14570911 DOI: 10.1074/Jbc.M304697200 |
0.831 |
|
| 2003 |
Chappell PE, White RS, Mellon PL. Circadian gene expression regulates pulsatile gonadotropin-releasing hormone (GnRH) secretory patterns in the hypothalamic GnRH-secreting GT1-7 cell line. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11202-13. PMID 14657179 DOI: 10.1523/Jneurosci.23-35-11202.2003 |
0.442 |
|
| 2003 |
Pernasetti F, Spady TJ, Hall SB, Rosenberg SB, Givens ML, Anderson S, Paulus M, Miller WL, Mellon PL. Pituitary tumorigenesis targeted by the ovine follicle-stimulating hormone beta-subunit gene regulatory region in transgenic mice. Molecular and Cellular Endocrinology. 203: 169-83. PMID 12782413 DOI: 10.1016/S0303-7207(02)00430-6 |
0.755 |
|
| 2003 |
Jacobs SB, Coss D, McGillivray SM, Mellon PL. Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene. Molecular Endocrinology (Baltimore, Md.). 17: 1470-83. PMID 12730328 DOI: 10.1210/Me.2002-0286 |
0.788 |
|
| 2002 |
Vasilyev VV, Pernasetti F, Rosenberg SB, Barsoum MJ, Austin DA, Webster NJ, Mellon PL. Transcriptional Activation of the Ovine Follicle-Stimulating Hormone-β Gene by Gonadotropin- Releasing Hormone Involves Multiple Signal Transduction Pathways. Endocrinology. 143: 1651-1659. PMID 28201639 DOI: 10.1210/endo.143.5.8771 |
0.746 |
|
| 2002 |
Kelley CG, Givens ML, Rave-Harel N, Nelson SB, Anderson S, Mellon PL. Neuron-restricted expression of the rat gonadotropin-releasing hormone gene is conferred by a cell-specific protein complex that binds repeated CAATT elements. Molecular Endocrinology (Baltimore, Md.). 16: 2413-25. PMID 12403831 DOI: 10.1210/Me.2002-0189 |
0.842 |
|
| 2002 |
Vasilyev VV, Lawson MA, Dipaolo D, Webster NJ, Mellon PL. Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRH. Endocrinology. 143: 3414-26. PMID 12193554 DOI: 10.1210/En.2001-211215 |
0.744 |
|
| 2002 |
Arroyo A, Pernasetti F, Vasilyev VV, Amato P, Yen SS, Mellon PL. A unique case of combined pituitary hormone deficiency caused by a PROP1 gene mutation (R120C) associated with normal height and absent puberty. Clinical Endocrinology. 57: 283-91. PMID 12153609 DOI: 10.1046/J.1365-2265.2002.01550.X |
0.717 |
|
| 2002 |
Rosenberg SB, Mellon PL. An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation. Molecular Endocrinology (Baltimore, Md.). 16: 1280-98. PMID 12040015 DOI: 10.1210/mend.16.6.0841 |
0.426 |
|
| 2002 |
Vasilyev VV, Pernasetti F, Rosenberg SB, Barsoum MJ, Austin DA, Webster NJ, Mellon PL. Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways. Endocrinology. 143: 1651-9. PMID 11956146 DOI: 10.1210/Endo.143.5.8771 |
0.799 |
|
| 2002 |
Holley SJ, Hall SB, Mellon PL. Complementary expression of IGF-II and IGFBP-5 during anterior pituitary development. Developmental Biology. 244: 319-28. PMID 11944940 DOI: 10.1006/dbio.2002.0608 |
0.307 |
|
| 2002 |
Lawson MA, Macconell LA, Kim J, Powl BT, Nelson SB, Mellon PL. Neuron-specific expression in vivo by defined transcription regulatory elements of the GnRH gene. Endocrinology. 143: 1404-12. PMID 11897697 DOI: 10.1210/endo.143.4.8751 |
0.478 |
|
| 2001 |
Pernasetti F, Vasilyev VV, Rosenberg SB, Bailey JS, Huang HJ, Miller WL, Mellon PL. Cell-Specific Transcriptional Regulation of Follicle-Stimulating Hormone-β by Activin and Gonadotropin-Releasing Hormone in the LβT2 Pituitary Gonadotrope Cell Model. Endocrinology. 142: 2284-2295. PMID 28201511 DOI: 10.1210/endo.142.6.8185 |
0.751 |
|
| 2001 |
Pernasetti F, Vasilyev VV, Rosenberg SB, Bailey JS, Huang HJ, Miller WL, Mellon PL. Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model. Endocrinology. 142: 2284-95. PMID 11356674 DOI: 10.1210/Endo.142.6.8185 |
0.797 |
|
| 2000 |
Sosnowski R, Mellon PL, Lawson MA. Activation of translation in pituitary gonadotrope cells by gonadotropin-releasing hormone Molecular Endocrinology. 14: 1811-1819. PMID 11075814 |
0.413 |
|
| 2000 |
Nelson SB, Lawson MA, Kelley CG, Mellon PL. Neuron-specific expression of the rat gonadotropin-releasing hormone gene is conferred by interactions of a defined promoter element with the enhancer in GT1-7 cells. Molecular Endocrinology (Baltimore, Md.). 14: 1509-22. PMID 10976927 DOI: 10.1210/Mend.14.9.0521 |
0.779 |
|
| 2000 |
Kelley CG, Lavorgna G, Clark ME, Boncinelli E, Mellon PL. The Otx2 homeoprotein regulates expression from the gonadotropin-releasing hormone proximal promoter. Molecular Endocrinology (Baltimore, Md.). 14: 1246-56. PMID 10935548 DOI: 10.1210/Mend.14.8.0509 |
0.804 |
|
| 2000 |
Belsham DD, Mellon PL. Transcription factors Oct-1 and C/EBP/β (CCAAT/enhancer-binding protein-β) are involved in the glutamate/nitric oxide/cyclic-guanosine 5′-monophosphate-mediated repression of gonadotropin-releasing hormone gene expression Molecular Endocrinology. 14: 212-228. PMID 10674395 DOI: 10.1210/me.14.2.212 |
0.4 |
|
| 2000 |
LiCalsi C, Christophe S, Steger DJ, Buescher M, Fischer W, Mellon PL. AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin Nucleic Acids Research. 28: 1036-1043. PMID 10648798 |
0.315 |
|
| 2000 |
Pernasetti F, Toledo SP, Vasilyev VV, Hayashida CY, Cogan JD, Ferrari C, Lourenço DM, Mellon PL. Impaired adrenocorticotropin-adrenal axis in combined pituitary hormone deficiency caused by a two-base pair deletion (301-302delAG) in the prophet of Pit-1 gene. The Journal of Clinical Endocrinology and Metabolism. 85: 390-7. PMID 10634415 DOI: 10.1210/Jcem.85.1.6324 |
0.716 |
|
| 1999 |
Kurotani R, Tahara S, Sanno N, Teramoto A, Mellon PL, Inoue K, Yoshimura S, Osamura RY. Expression of Ptx1 in the adult rat pituitary glands and pituitary cell lines: Hormone-secreting cells and folliculo-stellate cells Cell and Tissue Research. 298: 55-61. PMID 10555539 DOI: 10.1007/PL00008809 |
0.393 |
|
| 1999 |
MacConell LA, Lawson MA, Mellon PL, Roberts VJ. Activin A regulation of gonadotropin-releasing hormone synthesis and release in vitro Neuroendocrinology. 70: 246-254. PMID 10529619 DOI: 10.1159/000054483 |
0.531 |
|
| 1998 |
Yusta B, Alarid ET, Gordon DF, Ridgway EC, Mellon PL. The thyrotropin β-subunit gene is repressed by thyroid hormone in a novel thyrotrope cell line, mouse TαT1 cells Endocrinology. 139: 4476-4482. PMID 9794455 DOI: 10.1210/en.139.11.4476 |
0.408 |
|
| 1998 |
Lawson MA, Mellon PL. Expression of GATA-4 in migrating gonadotropin-releasing neurons of the developing mouse Molecular and Cellular Endocrinology. 140: 157-161. PMID 9722184 DOI: 10.1016/S0303-7207(98)00044-6 |
0.508 |
|
| 1998 |
Nelson SB, Eraly SA, Mellon PL. The GnRH promoter: target of transcription factors, hormones, and signaling pathways. Molecular and Cellular Endocrinology. 140: 151-5. PMID 9722183 DOI: 10.1016/S0303-7207(98)00043-4 |
0.445 |
|
| 1998 |
Harris AN, Mellon PL. The basic helix-loop-helix, leucine zipper transcription factor, USF (upstream stimulatory factor), is a key regulator of SF-1 (steroidogenic factor-1) gene expression in pituitary gonadotrope and steroidogenic cells. Molecular Endocrinology (Baltimore, Md.). 12: 714-26. PMID 9605934 DOI: 10.1210/mend.12.5.0100 |
0.48 |
|
| 1998 |
Eraly SA, Nelson SB, Huang KM, Mellon PL. Oct-1 binds promoter elements required for transcription of the GnRH gene. Molecular Endocrinology (Baltimore, Md.). 12: 469-81. PMID 9544983 DOI: 10.1210/mend.12.4.0092 |
0.491 |
|
| 1998 |
Lawson MA, Buhain AR, Jovenal JC, Mellon PL. Multiple factors interacting at the GATA sites of the gonadotropin-releasing hormone neuron-specific enhancer regulate gene expression Molecular Endocrinology. 12: 364-377. PMID 9514154 |
0.386 |
|
| 1997 |
Clark ME, Lawson MA, Belsham DD, Eraly SA, Mellon PL. Chapter 1 Molecular aspects of GnRH gene expression Advances in Molecular and Cellular Endocrinology. 1: 1-30. DOI: 10.1016/S1569-2566(97)80032-4 |
0.47 |
|
| 1996 |
Alarid ET, Windle JJ, Whyte DB, Mellon PL. Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice Development. 122: 3319-3329. PMID 8898243 |
0.385 |
|
| 1996 |
Turgeon JL, Kimura Y, Waring DW, Mellon PL. Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line Molecular Endocrinology. 10: 439-450. PMID 8721988 DOI: 10.1210/me.10.4.439 |
0.404 |
|
| 1996 |
Lawson MA, Whyte DB, Mellon PL. GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene Molecular and Cellular Biology. 16: 3596-3605. PMID 8668176 |
0.462 |
|
| 1996 |
Belsham DD, Wetsel WC, Mellon PL. NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression. The Embo Journal. 15: 538-47. PMID 8599937 DOI: 10.1002/J.1460-2075.1996.Tb00386.X |
0.404 |
|
| 1995 |
Alarid ET, Mellon PL. Down-regulation of the gonadotropin-releasing hormone receptor messenger ribonucleic acid by activation of adenylyl cyclase in αT3-1 pituitary gonadotrope cells Endocrinology. 136: 1361-1366. PMID 7895646 |
0.369 |
|
| 1995 |
Lawson MA, Whyte DB, Eraly SA, Mellon PL. Hypothalamus-specific regulation of gonadotropin-releasing hormone gene expression Recent Progress in Hormone Research. 50: 459-463. PMID 7740182 |
0.408 |
|
| 1995 |
Schechter J, Stauber C, Windle JJ, Mellon P. Basic fibroblast growth factor: The neurotrophic factor influencing the ingrowth of neural tissue into the anterior pituitary of α-T7 Transgenic mice? Neuroendocrinology. 61: 622-627. PMID 7659188 DOI: 10.1159/000126888 |
0.372 |
|
| 1995 |
Whyte DB, Lawson MA, Belsham DD, Eraly SA, Bond CT, Adelman JP, Mellon PL. A neuron-specific enhancer targets expression of the gonadotropin-releasing hormone gene to hypothalamic neurosecretory neurons Molecular Endocrinology. 9: 467-477. PMID 7659090 |
0.427 |
|
| 1995 |
Clark ME, Mellon PL. The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer Molecular and Cellular Biology. 15: 6169-6177. PMID 7565769 |
0.478 |
|
| 1995 |
Eraly SA, Mellon PL. Regulation of gonadotropin-releasing hormone transcription by protein kinase C is mediated by evolutionarily conserved promoter-proximal elements Molecular Endocrinology. 9: 848-859. PMID 7476968 |
0.42 |
|
| 1995 |
Mellon PL, Eraly SA, Belsham DD, Lawson MA, Clark ME, Whyte DB, Windle JJ. An Immortal Cell Culture Model of Hypothalamic Gonadotropin-Releasing Hormone Neurons Methods. 7: 303-310. DOI: 10.1006/meth.1995.1036 |
0.398 |
|
| 1994 |
Barnhart KM, Mellon PL. The orphan nuclear receptor, steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes Molecular Endocrinology. 8: 878-885. PMID 7527122 DOI: 10.1210/me.8.7.878 |
0.455 |
|
| 1994 |
Steger DJ, Hecht JH, Mellon PL. GATA-binding proteins regulate the human gonadotropin alpha-subunit gene in the placenta and pituitary gland. Molecular and Cellular Biology. 14: 5592-602. PMID 7518566 |
0.369 |
|
| 1993 |
Wetsel WC, Eraly SA, Whyte DB, Mellon PL. Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons. Endocrinology. 132: 2360-70. PMID 8504741 DOI: 10.1210/Endo.132.6.8504741 |
0.389 |
|
| 1993 |
Jackson SM, Barnhart KM, Mellon PL, Gutierrez-Hartmann A, Hoeffler JP. Helix-loop-helix proteins are present and differentially expressed in different cell lines from the anterior pituitary. Molecular and Cellular Endocrinology. 96: 167-76. PMID 8276132 DOI: 10.1016/0303-7207(93)90107-U |
0.337 |
|
| 1993 |
Lew D, Brady H, Klausing K, Yaginuma K, Theill LE, Stauber C, Karin M, Mellon PL. GHF-1 - promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice Genes and Development. 7: 683-693. PMID 8096199 DOI: 10.1101/Gad.7.4.683 |
0.419 |
|
| 1993 |
Steger DJ, Büscher M, Hecht JH, Mellon PL. Coordinate control of the alpha- and beta-subunit genes of human chorionic gonadotropin by trophoblast-specific element-binding protein. Molecular Endocrinology (Baltimore, Md.). 7: 1579-88. PMID 7511787 DOI: 10.1210/mend.7.12.7511787 |
0.343 |
|
| 1992 |
Wetsel WC, Valença MM, Merchenthaler I, Liposits Z, López FJ, Weiner RI, Mellon PL, Negro-Vilar A. Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. Proceedings of the National Academy of Sciences of the United States of America. 89: 4149-53. PMID 1570341 DOI: 10.1073/Pnas.89.9.4149 |
0.396 |
|
| 1992 |
Weiner RI, Wetsel W, Goldsmith P, Martinez de la Escalera G, Windle J, Padula C, Choi A, Negro-Vilar A, Mellon P. Gonadotropin-releasing hormone neuronal cell lines. Frontiers in Neuroendocrinology. 13: 95-119. PMID 1468602 |
0.407 |
|
| 1992 |
Stauber C, Altschmied J, Akerblom IE, Marron JL, Mellon PL. Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells The New Biologist. 4: 527-540. PMID 1387550 |
0.347 |
|
| 1992 |
Schoderbek WE, Kim KE, Ridgway EC, Mellon PL, Maurer RA. Analysis of DNA sequences required for pituitary-specific expression of the glycoprotein hormone α-subunit gene Molecular Endocrinology. 6: 893-903. PMID 1379672 |
0.394 |
|
| 1992 |
Horn F, Windle JJ, Barnhart KM, Mellon PL. Tissue-specific gene expression in the pituitary: The glycoprotein hormone α-subunit gene is regulated by a gonadotrope-specific protein Molecular and Cellular Biology. 12: 2143-2153. PMID 1373809 |
0.496 |
|
| 1992 |
Mellon PL, Wetsel WC, Windle JJ, Valença MM, Goldsmith PC, Whyte DB, Eraly SA, Negro-Vilar A, Weiner RI. Immortalized hypothalamic gonadotropin-releasing hormone neurons. Ciba Foundation Symposium. 168: 104-17; discussion 1. PMID 1330456 |
0.424 |
|
| 1992 |
Tsutsumi M, Zhou W, Millar RP, Mellon PL, Roberts JL, Flanagan CA, Dong K, Gillo B, Sealfon SC. Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. Molecular Endocrinology (Baltimore, Md.). 6: 1163-9. PMID 1324422 DOI: 10.1210/Mend.6.7.1324422 |
0.375 |
|
| 1991 |
Gonzalez-Manchon C, Bilezikjian LM, Corrigan AZ, Mellon PL, Vale W. Activin-A modulates gonadotropin-releasing hormone secretion from a gonadotropin-releasing hormone-secreting neuronal cell line Neuroendocrinology. 54: 373-377. PMID 1758579 DOI: 10.1159/000125916 |
0.402 |
|
| 1991 |
Mellon PL, Windle JJ, Weiner RI. Immortalization of neuroendocrine cells by targeted oncogenesis. Recent Progress in Hormone Research. 47: 69-93; discussion 93. PMID 1745826 DOI: 10.1016/B978-0-12-571147-0.50007-X |
0.421 |
|
| 1991 |
Wetsel WC, Mellon PL, Weiner RI, Negro-Vilar A. Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons. Endocrinology. 129: 1584-95. PMID 1714837 DOI: 10.1210/Endo-129-3-1584 |
0.316 |
|
| 1991 |
Steger DJ, Altschmied J, Buscher M, Mellon PL. Evolution of placenta-specific gene expression: Comparison of the equine and human gonadotropin α-subunit genes Molecular Endocrinology. 5: 243-255. PMID 1710031 |
0.369 |
|
| 1991 |
Horn F, Bilezikjian LM, Perrin MH, Bosma MM, Windle JJ, Huber KS, Blount AL, Hille B, Vale W, Mellon PL. Intracellular responses to gonadotropin-releasing hormone in a clonal cell line of the gonadotrope lineage. Molecular Endocrinology (Baltimore, Md.). 5: 347-55. PMID 1653891 DOI: 10.1210/mend-5-3-347 |
0.379 |
|
| 1990 |
Mellon PL, Windle JJ, Goldsmith PC, Padula CA, Roberts JL, Weiner RI. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron. 5: 1-10. PMID 2196069 DOI: 10.1016/0896-6273(90)90028-E |
0.357 |
|
| 1990 |
Collins S, Altschmied J, Herbsman O, Caron MG, Mellon PL, Lefkowitz RJ. A cAMP response element in the β2-adrenergic receptor gene confers transcriptional autoregulation by cAMP Journal of Biological Chemistry. 265: 19330-19335. PMID 2172252 |
0.317 |
|
| 1990 |
Windle JJ, Weiner RI, Mellon PL. Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 4: 597-603. PMID 1704103 DOI: 10.1210/mend-4-4-597 |
0.393 |
|
| 1990 |
O'brien JM, Marcus DM, Bernards R, Carpenter JL, Windle JJ, Mellon P, Albert DM. A Transgenic Mouse Model for Trilateral Retinoblastoma Archives of Ophthalmology. 108: 1145-1151. PMID 1696469 DOI: 10.1001/Archopht.1990.01070100101043 |
0.347 |
|
| 1989 |
Mellon PL, Clegg CH, Correll LA, McKnight GS. Regulation of transcription by cyclic AMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 86: 4887-4891. PMID 2544878 |
0.361 |
|
| 1988 |
Sassone-Corsi P, Visvader J, Ferland L, Mellon PL, Verma IM. Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element. Genes & Development. 2: 1529-38. PMID 2850967 DOI: 10.1101/Gad.2.12A.1529 |
0.372 |
|
| 1988 |
Akerblom IE, Slater EP, Beato M, Baxter JD, Mellon PL. Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science (New York, N.Y.). 241: 350-3. PMID 2838908 DOI: 10.1126/Science.2838908 |
0.475 |
|
| 1987 |
Isaacs RE, Findell PR, Mellon P, Wilson CB, Baxter JD. Hormonal regulation of expression of the endogenous and transfected human growth hormone gene Molecular Endocrinology (Baltimore, Md.). 1: 569-576. PMID 3153479 DOI: 10.1210/Mend-1-8-569 |
0.451 |
|
| 1986 |
Cattini PA, Anderson TR, Baxter JD, Mellon P, Eberhardt NL. The human growth hormone gene is negatively regulated by triiodothyronine when transfected into rat pituitary tumor cells Journal of Biological Chemistry. 261: 13367-13372. PMID 2428817 |
0.439 |
|
| 1985 |
Charnay P, Mellon P, Maniatis T. Linker scanning mutagenesis of the 5'-flanking region of the mouse beta-major-globin gene: sequence requirements for transcription in erythroid and nonerythroid cells. Molecular and Cellular Biology. 5: 1498-511. PMID 3861935 DOI: 10.1128/Mcb.5.6.1498 |
0.479 |
|
| 1985 |
Slater EP, Anderson TR, Cattini PA, Eberhardt NL, Karin M, Mellon PL, Baxter JD. Tissue-specific influences affect glucocorticoid regulatory element actions on the human growth hormone gene promotor Transactions of the Association of American Physicians. 98: 66-73. PMID 3842208 |
0.329 |
|
| 1984 |
Charnay P, Treisman R, Mellon P, Chao M, Axel R, Maniatis T. Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences. Cell. 38: 251-63. PMID 6205764 DOI: 10.1016/0092-8674(84)90547-6 |
0.425 |
|
| 1984 |
Charnay P, Treisman R, Mellon P, Chao M, Axel R, Maniatis T. Human alpha- and beta-globin gene transcription in mouse erythroleukaemia cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 261-70. PMID 6151696 DOI: 10.1098/Rstb.1984.0126 |
0.424 |
|
| 1983 |
Mellon P, Charnay P, Chao M, Axel R, Maniatis T. Regulated expression of cloned globin genes introduced into mouse erythroleukemia cells. Progress in Clinical and Biological Research. 134: 3-12. PMID 6582520 |
0.383 |
|
| 1983 |
Chao MV, Mellon P, Charnay P, Maniatis T, Axel R. The regulated expression of beta-globin genes introduced into mouse erythroleukemia cells. Cell. 32: 483-93. PMID 6572107 DOI: 10.1016/0092-8674(83)90468-3 |
0.473 |
|
| 1983 |
Chao MV, Mellon P, Charnay P, Maniatis T, Axel R. Introduction and expression of beta-globin genes in murine erythroleukemic cells. Gene Amplification and Analysis. 3: 215-31. PMID 6101028 |
0.3 |
|
| 1982 |
Zinn K, Mellon P, Ptashne M, Maniatis T. Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4897-901. PMID 6956899 DOI: 10.1073/Pnas.79.16.4897 |
0.367 |
|
| 1981 |
Mellon P, Parker V, Gluzman Y, Maniatis T. Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system Cell. 27: 279-288. PMID 6277501 DOI: 10.1016/0092-8674(81)90411-6 |
0.376 |
|
| 1977 |
Folkmanis A, Maltzman W, Mellon P, Skalka A, Echols H. The essential role of the cro gene in lytic development by bacteriophage λ Virology. 81: 352-362. PMID 898664 DOI: 10.1016/0042-6822(77)90151-9 |
0.306 |
|
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