Steven T. Gregory - Publications

Affiliations: 
Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Silvia S, Donahue SA, Killeavy EE, Jogl G, Gregory ST. A Survey of Spontaneous Antibiotic-Resistant Mutants of the Halophilic, Thermophilic Bacterium . Antibiotics (Basel, Switzerland). 10. PMID 34827322 DOI: 10.3390/antibiotics10111384  0.565
2021 Svetlov MS, Syroegin EA, Aleksandrova EV, Atkinson GC, Gregory ST, Mankin AS, Polikanov YS. Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nature Chemical Biology. PMID 33462493 DOI: 10.1038/s41589-020-00715-0  0.321
2020 Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory ST, Murray BE, Krause KL, Khayat R, Jogl G. Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis. Scientific Reports. 10: 16301. PMID 33004869 DOI: 10.1038/s41598-020-73199-6  0.314
2020 Younkin AD, Gregory ST, O'Connor M. Alterations in the ribosomal protein bL12 of E. coli affecting the initiation, elongation and termination of protein synthesis. Biochimie. 175: 173-180. PMID 32569619 DOI: 10.1016/j.biochi.2020.06.006  0.342
2020 Killeavy EE, Jogl G, Gregory ST. Tiamulin-Resistant Mutants of the Thermophilic Bacterium . Antibiotics (Basel, Switzerland). 9. PMID 32526926 DOI: 10.3390/Antibiotics9060313  0.391
2017 Kamath D, Allgeyer BB, Gregory ST, Bielski MC, Roelofsz DM, Sabapathypillai SL, Vaid N, O'Connor M. The C-terminus of ribosomal protein uS4 contributes to small ribosomal subunit biogenesis and the fidelity of translation. Biochimie. PMID 28483689 DOI: 10.1016/J.Biochi.2017.05.004  0.426
2016 Kamath D, Gregory ST, O'Connor M. The Loop 2 Region of Ribosomal Protein uS5 Influences Spectinomycin Sensitivity, Translational Fidelity and Ribosome Biogenesis. Antimicrobial Agents and Chemotherapy. PMID 27855073 DOI: 10.1128/Aac.01186-16  0.457
2016 VanNice J, Gregory ST, Kamath D, O'Connor M. Alterations in Ribosomal Protein L19 that Decrease the Fidelity of Translation. Biochimie. PMID 27477481 DOI: 10.1016/J.Biochi.2016.07.015  0.438
2015 Carr JF, Lee HJ, Jaspers JB, Dahlberg AE, Jogl G, Gregory ST. Phenotypic suppression of streptomycin-resistance by mutations in multiple components of the translation apparatus. Journal of Bacteriology. PMID 26148717 DOI: 10.1128/Jb.00219-15  0.515
2015 Carr JF, Danziger ME, Huang AL, Dahlberg AE, Gregory ST. Engineering the genome of Thermus thermophilus using a counterselectable marker. Journal of Bacteriology. 197: 1135-44. PMID 25605305 DOI: 10.1128/Jb.02384-14  0.43
2015 Agarwal D, Kamath D, Gregory ST, O'Connor M. Modulation of decoding fidelity by ribosomal proteins S4 and S5. Journal of Bacteriology. 197: 1017-25. PMID 25548247 DOI: 10.1128/Jb.02485-14  0.474
2015 Carr JF, Gregory ST, Dahlberg AE. Transposon mutagenesis of the extremely thermophilic bacterium Thermus thermophilus HB27. Extremophiles : Life Under Extreme Conditions. 19: 221-8. PMID 24948436 DOI: 10.1007/S00792-014-0663-8  0.33
2014 Gregory ST, Connetti JL, Carr JF, Jogl G, Dahlberg AE. Phenotypic interactions among mutations in a Thermus thermophilus 16S rRNA gene detected with genetic selections and experimental evolution. Journal of Bacteriology. 196: 3776-83. PMID 25157075 DOI: 10.1128/Jb.02104-14  0.488
2014 Demirci H, Murphy FV, Murphy EL, Connetti JL, Dahlberg AE, Jogl G, Gregory ST. Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance. Antimicrobial Agents and Chemotherapy. 58: 4308-17. PMID 24820088 DOI: 10.1128/Aac.02857-14  0.463
2013 Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF, Blanchard SC, Jogl G, Dahlberg AE, Gregory ST. The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna (New York, N.Y.). 19: 1791-801. PMID 24152548 DOI: 10.1261/Rna.040030.113  0.442
2013 Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg AE, Jogl G. A structural basis for streptomycin-induced misreading of the genetic code. Nature Communications. 4: 1355. PMID 23322043 DOI: 10.1038/Ncomms2346  0.388
2011 Agarwal D, Gregory ST, O'Connor M. Error-prone and error-restrictive mutations affecting ribosomal protein S12. Journal of Molecular Biology. 410: 1-9. PMID 21575643 DOI: 10.1016/J.Jmb.2011.04.068  0.481
2011 O'Connor M, Gregory ST. Inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function in wild-type Escherichia coli and Salmonella enterica. Journal of Bacteriology. 193: 154-62. PMID 21037010 DOI: 10.1128/Jb.00970-10  0.378
2010 Demirci H, Murphy F, Belardinelli R, Kelley AC, Ramakrishnan V, Gregory ST, Dahlberg AE, Jogl G. Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function. Rna (New York, N.Y.). 16: 2319-24. PMID 20962038 DOI: 10.1261/Rna.2357210  0.414
2010 Demirci H, Larsen LH, Hansen T, Rasmussen A, Cadambi A, Gregory ST, Kirpekar F, Jogl G. Multi-site-specific 16S rRNA methyltransferase RsmF from Thermus thermophilus. Rna (New York, N.Y.). 16: 1584-96. PMID 20558545 DOI: 10.1261/Rna.2088310  0.323
2009 Gregory ST. Structural Basis for the Decoding Mechanism. Ecosal Plus. 3. PMID 26443766 DOI: 10.1128/ecosalplus.2.5.4  0.35
2009 Gregory ST, Demirci H, Belardinelli R, Monshupanee T, Gualerzi C, Dahlberg AE, Jogl G. Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG. Rna (New York, N.Y.). 15: 1693-704. PMID 19622680 DOI: 10.1261/Rna.1652709  0.417
2009 Demirci H, Belardinelli R, Seri E, Gregory ST, Gualerzi C, Dahlberg AE, Jogl G. Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. Journal of Molecular Biology. 388: 271-82. PMID 19285505 DOI: 10.1016/J.Jmb.2009.02.066  0.423
2009 Gregory ST, Dahlberg AE. Genetic and structural analysis of base substitutions in the central pseudoknot of Thermus thermophilus 16S ribosomal RNA. Rna (New York, N.Y.). 15: 215-23. PMID 19144908 DOI: 10.1261/Rna.1374809  0.459
2009 Gregory ST, Carr JF, Dahlberg AE. A signal relay between ribosomal protein S12 and elongation factor EF-Tu during decoding of mRNA. Rna (New York, N.Y.). 15: 208-14. PMID 19095621 DOI: 10.1261/Rna.1355709  0.472
2008 Monshupanee T, Gregory ST, Douthwaite S, Chungjatupornchai W, Dahlberg AE. Mutations in conserved helix 69 of 23S rRNA of Thermus thermophilus that affect capreomycin resistance but not posttranscriptional modifications. Journal of Bacteriology. 190: 7754-61. PMID 18805973 DOI: 10.1128/Jb.00984-08  0.501
2008 Demirci H, Gregory ST, Dahlberg AE, Jogl G. Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine. The Journal of Biological Chemistry. 283: 26548-56. PMID 18667428 DOI: 10.1074/Jbc.M804005200  0.412
2008 Demirci H, Gregory ST, Dahlberg AE, Jogl G. Multiple-site trimethylation of ribosomal protein L11 by the PrmA methyltransferase. Structure (London, England : 1993). 16: 1059-66. PMID 18611379 DOI: 10.1016/J.Str.2008.03.016  0.385
2008 Demirci H, Gregory S, Dahlberg A, Jogl G. Recognition and catalysis of ribosomal protein L11 by the protein trimethyltransferase PrmA Acta Crystallographica Section a Foundations of Crystallography. 64: C374-C374. DOI: 10.1107/S0108767308088065  0.334
2007 Demirci H, Gregory ST, Dahlberg AE, Jogl G. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. The Embo Journal. 26: 567-77. PMID 17215866 DOI: 10.1038/Sj.Emboj.7601508  0.375
2006 Carr JF, Hamburg DM, Gregory ST, Limbach PA, Dahlberg AE. Effects of streptomycin resistance mutations on posttranslational modification of ribosomal protein S12. Journal of Bacteriology. 188: 2020-3. PMID 16484214 DOI: 10.1128/Jb.188.5.2020-2023.2006  0.422
2005 Suh MJ, Hamburg DM, Gregory ST, Dahlberg AE, Limbach PA. Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry. Proteomics. 5: 4818-31. PMID 16287167 DOI: 10.1002/Pmic.200402111  0.33
2005 Gregory ST, Carr JF, Rodriguez-Correa D, Dahlberg AE. Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus. Journal of Bacteriology. 187: 4804-12. PMID 15995195 DOI: 10.1128/Jb.187.14.4804-4812.2005  0.497
2005 Carr JF, Gregory ST, Dahlberg AE. Severity of the streptomycin resistance and streptomycin dependence phenotypes of ribosomal protein S12 of Thermus thermophilus depends on the identity of highly conserved amino acid residues. Journal of Bacteriology. 187: 3548-50. PMID 15866943 DOI: 10.1128/Jb.187.10.3548-3550.2005  0.474
2005 Gregory ST, Carr JF, Dahlberg AE. A mutation in the decoding center of Thermus thermophilus 16S rRNA suggests a novel mechanism of streptomycin resistance. Journal of Bacteriology. 187: 2200-2. PMID 15743969 DOI: 10.1128/Jb.187.6.2200-2202.2005  0.426
2004 O'Connor M, Gregory ST, Dahlberg AE. Multiple defects in translation associated with altered ribosomal protein L4. Nucleic Acids Research. 32: 5750-6. PMID 15509870 DOI: 10.1093/Nar/Gkh913  0.489
2004 Cameron DM, Gregory ST, Thompson J, Suh MJ, Limbach PA, Dahlberg AE. Thermus thermophilus L11 methyltransferase, PrmA, is dispensable for growth and preferentially modifies free ribosomal protein L11 prior to ribosome assembly. Journal of Bacteriology. 186: 5819-25. PMID 15317787 DOI: 10.1128/Jb.186.17.5819-5825.2004  0.382
2004 Cameron DM, Thompson J, Gregory ST, March PE, Dahlberg AE. Thiostrepton-resistant mutants of Thermus thermophilus. Nucleic Acids Research. 32: 3220-7. PMID 15199170 DOI: 10.1093/Nar/Gkh644  0.519
2001 Gregory ST, Bayfield MA, O'Connor M, Thompson J, Dahlberg AE. Probing ribosome structure and function by mutagenesis. Cold Spring Harbor Symposia On Quantitative Biology. 66: 101-8. PMID 12762012 DOI: 10.1101/Sqb.2001.66.101  0.323
2001 Gabashvili IS, Gregory ST, Valle M, Grassucci R, Worbs M, Wahl MC, Dahlberg AE, Frank J. The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Molecular Cell. 8: 181-8. PMID 11511371 DOI: 10.1016/S1097-2765(01)00293-3  0.401
2001 Thompson J, Kim DF, O'Connor M, Lieberman KR, Bayfield MA, Gregory ST, Green R, Noller HF, Dahlberg AE. Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 98: 9002-7. PMID 11470897 DOI: 10.1073/Pnas.151257098  0.462
2001 O'Connor M, Gregory ST, Rajbhandary UL, Dahlberg AE. Altered discrimination of start codons and initiator tRNAs by mutant initiation factor 3. Rna (New York, N.Y.). 7: 969-78. PMID 11453069 DOI: 10.1017/S1355838201010184  0.411
2001 Gregory ST, Cate JH, Dahlberg AE. Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21. Journal of Bacteriology. 183: 4382-5. PMID 11418580 DOI: 10.1128/Jb.183.14.4382-4385.2001  0.449
2001 Gregory ST, Cate JH, Dahlberg AE. Streptomycin-resistant and streptomycin-dependent mutants of the extreme thermophile Thermus thermophilus. Journal of Molecular Biology. 309: 333-8. PMID 11371156 DOI: 10.1006/Jmbi.2001.4676  0.526
1999 Gregory ST, Dahlberg AE. Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. Journal of Molecular Biology. 289: 827-34. PMID 10369764 DOI: 10.1006/Jmbi.1999.2839  0.485
1999 Gregory ST, Dahlberg AE. Mutations in the conserved P loop perturb the conformation of two structural elements in the peptidyl transferase center of 23 S ribosomal RNA. Journal of Molecular Biology. 285: 1475-83. PMID 9917390 DOI: 10.1006/Jmbi.1998.2410  0.427
1996 Gregory ST, O'Connor M, Dahlberg AE. Functional Escherichia coli 23S rRNAs containing processed and unprocessed intervening sequences from Salmonella typhimurium. Nucleic Acids Research. 24: 4918-23. PMID 9016661 DOI: 10.1093/Nar/24.24.4918  0.462
1995 O'Connor M, Brunelli CA, Firpo MA, Gregory ST, Lieberman KR, Lodmell JS, Moine H, Van Ryk DI, Dahlberg AE. Genetic probes of ribosomal RNA function. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 859-68. PMID 8722001 DOI: 10.1139/O95-093  0.445
1995 Gregory ST, Dahlberg AE. Effects of mutations at position 36 of tRNA(Glu) on missense and nonsense suppression in Escherichia coli. Febs Letters. 361: 25-8. PMID 7890035 DOI: 10.1016/0014-5793(95)00132-S  0.451
1995 Gregory ST, Dahlberg AE. Nonsense suppressor and antisuppressor mutations at the 1409-1491 base pair in the decoding region of Escherichia coli 16S rRNA. Nucleic Acids Research. 23: 4234-8. PMID 7501440 DOI: 10.1093/Nar/23.21.4234  0.455
1994 Gregory ST, Lieberman KR, Dahlberg AE. Mutations in the peptidyl transferase region of E. coli 23S rRNA affecting translational accuracy. Nucleic Acids Research. 22: 279-84. PMID 8127663 DOI: 10.1093/Nar/22.3.279  0.459
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