Philip A. Gruppuso - Publications

Affiliations: 
Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Raigani S, Santiago J, Ohman A, Heaney M, Baptista S, Coe TM, de Vries RJ, Rosales I, Shih A, Markmann JF, Gruppuso P, Uygun K, Sanders J, Yeh H. Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates innate immune responses. Frontiers in Immunology. 13: 940094. PMID 35958587 DOI: 10.3389/fimmu.2022.940094  0.626
2021 Ohman A, Raigani S, Santiago JC, Heaney MG, Boylan JM, Parry N, Carroll C, Baptista SG, Uygun K, Gruppuso PA, Sanders JA, Yeh H. Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 34730028 DOI: 10.1152/ajpgi.00266.2021  0.645
2021 Santiago JC, Boylan JM, Lemieux FA, Gruppuso PA, Sanders JA, Rand DM. Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila. Bmc Genomics. 22: 213. PMID 33761878 DOI: 10.1186/s12864-021-07516-2  0.557
2019 Zabala V, Boylan JM, Thevenot P, Frank A, Senthoor D, Iyengar V, Kim H, Cohen A, Gruppuso PA, Sanders JA. Transcriptional changes during hepatic ischemia-reperfusion in the rat. Plos One. 14: e0227038. PMID 31891620 DOI: 10.1371/Journal.Pone.0227038  0.642
2019 Hodax JK, Quintos JB, Gruppuso PA, Chen Q, Desai S, Jayasuriya CT. Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells. Plos One. 14: e0218399. PMID 31206541 DOI: 10.1371/Journal.Pone.0218399  0.349
2018 Chorzalska A, Morgan J, Ahsan N, Treaba DO, Olszewski AJ, Petersen M, Kingston N, Cheng Y, Lombardo K, Schorl C, Yu X, Zini R, Pacilli A, Tepper A, Coburn J, ... ... Gruppuso PA, et al. Bone marrow-specific loss of induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. PMID 30213875 DOI: 10.1182/Blood-2018-05-848408  0.309
2018 Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA. Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells. Plos One. 13: e0203351. PMID 30192817 DOI: 10.1371/Journal.Pone.0203351  0.622
2018 Hurley E, Zabala V, Boylan JM, Gruppuso PA, Sanders JA. Hepatic Gene Expression during the Perinatal Transition in the Rat. Gene Expression. PMID 29929573 DOI: 10.3727/105221618X15293258688953  0.66
2018 Chorzalska A, Ahsan N, Rao RSP, Roder K, Yu X, Morgan J, Tepper A, Hines S, Zhang P, Treaba DO, Zhao TC, Olszewski AJ, Reagan J, Liang O, Gruppuso PA, et al. Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of Chronic Myeloid Leukemia. Molecular Oncology. PMID 29485707 DOI: 10.1002/1878-0261.12186  0.329
2017 Boylan JM, Francois-Vaughan H, Gruppuso PA, Sanders JA. Engraftment and Repopulation Potential of Late Gestation Fetal Rat Hepatocytes. Transplantation. PMID 28749819 DOI: 10.1097/Tp.0000000000001882  0.694
2017 Adebayo Michael AO, Ahsan N, Zabala V, Francois-Vaughan H, Post S, Brilliant KE, Salomon AR, Sanders JA, Gruppuso PA. Proteomic analysis of laser capture microdissected focal lesions in a rat model of progenitor marker-positive hepatocellular carcinoma. Oncotarget. PMID 28199961 DOI: 10.18632/Oncotarget.15219  0.665
2016 Boylan JM, Sanders JA, Gruppuso PA. Regulation of Fetal Liver Growth in a Model of Diet Restriction in the Pregnant Rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00138.2016. PMID 27357801 DOI: 10.1152/Ajpregu.00138.2016  0.714
2016 Francois-Vaughan H, Adebayo AO, Brilliant KE, Parry NM, Gruppuso PA, Sanders JA. Persistent Effect of mTOR Inhibition on Preneoplastic Foci Progression and Gene Expression in a Rat Model of Hepatocellular Carcinoma. Carcinogenesis. PMID 26905589 DOI: 10.1093/Carcin/Bgw016  0.69
2016 Gruppuso PA, Sanders JA. Regulation of liver development: implications for liver biology across the lifespan. Journal of Molecular Endocrinology. PMID 26887388 DOI: 10.1530/Jme-15-0313  0.705
2015 Huse SM, Gruppuso PA, Boekelheide K, Sanders JA. Patterns of gene expression and DNA methylation in human fetal and adult liver. Bmc Genomics. 16: 981. PMID 26589361 DOI: 10.1186/S12864-015-2066-3  0.652
2015 Boylan JM, Salomon AR, Tantravahi U, Gruppuso PA. Adaptation of HepG2 cells to a steady-state reduction in the content of protein phosphatase 6 (PP6) catalytic subunit. Experimental Cell Research. 335: 224-37. PMID 25999147 DOI: 10.1016/J.Yexcr.2015.05.008  0.397
2015 Boylan JM, Sanders JA, Neretti N, Gruppuso PA. Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R22-35. PMID 25924882 DOI: 10.1152/Ajpregu.00114.2015  0.719
2015 Adebayo AO, Zandbergen F, Kozul-Horvath CD, Gruppuso PA, Hamilton JW. Chronic exposure to low-dose arsenic modulates lipogenic gene expression in mice. Journal of Biochemical and Molecular Toxicology. 29: 1-9. PMID 25155036 DOI: 10.1002/Jbt.21600  0.357
2015 Francois-Vaughan H, Brilliant K, Adebayo AO, Parry NMA, Gruppuso PA, Sanders JA. Abstract B55: mTOR signaling is critical to the development and expansion of preneoplastic foci in a rodent model of progenitor-marker positive hepatocellular carcinoma Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-B55  0.658
2014 Spade DJ, McDonnell EV, Heger NE, Sanders JA, Saffarini CM, Gruppuso PA, De Paepe ME, Boekelheide K. Xenotransplantation models to study the effects of toxicants on human fetal tissues. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 410-22. PMID 25477288 DOI: 10.1002/Bdrb.21131  0.611
2014 Garcia B, Francois-Vaughan H, Onikoyi O, Kostadinov S, De Paepe ME, Gruppuso PA, Sanders JA. Xenotransplantation of human fetal adipose tissue: a model of in vivo adipose tissue expansion and adipogenesis. Journal of Lipid Research. 55: 2685-91. PMID 25193996 DOI: 10.1194/Jlr.D052787  0.62
2014 Lamming DW, Demirkan G, Boylan JM, Mihaylova MM, Peng T, Ferreira J, Neretti N, Salomon A, Sabatini DM, Gruppuso PA. Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 300-15. PMID 24072782 DOI: 10.1096/Fj.13-237743  0.399
2014 Sanders JA, Gruppuso PA. Hepatic, pancreatic and biliary cancers Translation and Its Regulation in Cancer Biology and Medicine. 611-629. DOI: 10.1007/978-94-017-9078-9_30  0.582
2012 Demirkan G, Salomon AR, Gruppuso PA. Phosphoproteomic analysis of liver homogenates. Methods in Molecular Biology (Clifton, N.J.). 909: 151-63. PMID 22903715 DOI: 10.1007/978-1-61779-959-4_11  0.41
2012 Sanders JA, Brilliant KE, Clift D, Patel A, Cerretti B, Claro P, Mills DR, Hixson DC, Gruppuso PA. The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. Experimental and Molecular Pathology. 93: 40-9. PMID 22525806 DOI: 10.1016/J.Yexmp.2012.04.002  0.694
2012 Sanders JA, Schorl C, Patel A, Sedivy JM, Gruppuso PA. Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion. Bmc Physiology. 12: 1. PMID 22397685 DOI: 10.1186/1472-6793-12-1  0.676
2011 Villa-Cuesta E, Boylan JM, Tatar M, Gruppuso PA. Resveratrol inhibits protein translation in hepatic cells. Plos One. 6: e29513. PMID 22242130 DOI: 10.1371/Journal.Pone.0029513  0.37
2011 Demirkan G, Yu K, Boylan JM, Salomon AR, Gruppuso PA. Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1). Plos One. 6: e21729. PMID 21738781 DOI: 10.1371/Journal.Pone.0021729  0.394
2011 Gruppuso PA, Boylan JM, Sanders JA. The physiology and pathophysiology of rapamycin resistance: implications for cancer. Cell Cycle (Georgetown, Tex.). 10: 1050-8. PMID 21389767 DOI: 10.4161/Cc.10.7.15230  0.684
2010 Temu TM, Wu KY, Gruppuso PA, Phornphutkul C. The mechanism of ascorbic acid-induced differentiation of ATDC5 chondrogenic cells. American Journal of Physiology. Endocrinology and Metabolism. 299: E325-34. PMID 20530736 DOI: 10.1152/Ajpendo.00145.2010  0.312
2010 Jimenez RH, Lee JS, Francesconi M, Castellani G, Neretti N, Sanders JA, Sedivy J, Gruppuso PA. Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR). Plos One. 5: e9084. PMID 20140209 DOI: 10.1371/Journal.Pone.0009084  0.778
2009 Jimenez RH, Boylan JM, Lee JS, Francesconi M, Castellani G, Sanders JA, Gruppuso PA. Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines. Plos One. 4: e7373. PMID 19816606 DOI: 10.1371/Journal.Pone.0007373  0.776
2009 Kim MS, Wu KY, Auyeung V, Chen Q, Gruppuso PA, Phornphutkul C. Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling. American Journal of Physiology. Endocrinology and Metabolism. 296: E1374-82. PMID 19401455 DOI: 10.1152/Ajpendo.91018.2008  0.398
2008 Gruppuso PA, Tsai SW, Boylan JM, Sanders JA. Hepatic translation control in the late-gestation fetal rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R558-67. PMID 18565838 DOI: 10.1152/Ajpregu.00091.2008  0.712
2008 Sanders JA, Lakhani A, Phornphutkul C, Wu KY, Gruppuso PA. The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats. American Journal of Physiology. Cell Physiology. 295: C406-13. PMID 18550700 DOI: 10.1152/Ajpcell.00450.2007  0.692
2008 Yoo SJ, Jimenez RH, Sanders JA, Boylan JM, Brautigan DL, Gruppuso PA. The alpha4-containing form of protein phosphatase 2A in liver and hepatic cells. Journal of Cellular Biochemistry. 105: 290-300. PMID 18543252 DOI: 10.1002/Jcb.21830  0.773
2008 Phornphutkul C, Wu KY, Auyeung V, Chen Q, Gruppuso PA. mTOR signaling contributes to chondrocyte differentiation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 702-12. PMID 18265001 DOI: 10.1002/Dvdy.21464  0.416
2007 Yoo SJ, Boylan JM, Brautigan DL, Gruppuso PA. Subunit composition and developmental regulation of hepatic protein phosphatase 2A (PP2A). Archives of Biochemistry and Biophysics. 461: 186-93. PMID 17391644 DOI: 10.1016/J.Abb.2007.02.019  0.635
2007 Sanders JA, Lakhani A, Gruppuso PA. Cell Proliferation in Multiple Rat Tissues In Vivo is Rapamycin Resistant The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A289-A  0.633
2007 Tsai S, Boylan JM, Sanders JA, Gruppuso PA. Hepatic translation control in late gestation fetal rats versus adult rats The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A288-D  0.654
2006 Phornphutkul C, Wu KY, Gruppuso PA. The role of insulin in chondrogenesis. Molecular and Cellular Endocrinology. 249: 107-15. PMID 16530934 DOI: 10.1016/J.Mce.2006.02.002  0.311
2006 Anand P, Gruppuso PA. Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation. The Journal of Nutrition. 136: 27-33. PMID 16365054 DOI: 10.1093/Jn/136.1.27  0.666
2006 Sanders JA, Gruppuso PA. Coordinated regulation of c-Myc and Max in rat liver development. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G145-55. PMID 16150871 DOI: 10.1152/Ajpgi.00545.2004  0.692
2005 Embree-Ku M, Gruppuso PA. The role of nuclear factor kappaB in late-gestation liver development in the rat. Hepatology (Baltimore, Md.). 42: 326-34. PMID 16025516 DOI: 10.1002/Hep.20796  0.432
2005 Boylan JM, Gruppuso PA. D-type cyclins and G1 progression during liver development in the rat. Biochemical and Biophysical Research Communications. 330: 722-30. PMID 15809057 DOI: 10.1016/J.Bbrc.2005.03.042  0.409
2005 Sanders JA, Gruppuso PA. Nucleolar localization of hepatic c-Myc: a potential mechanism for c-Myc regulation. Biochimica Et Biophysica Acta. 1743: 141-50. PMID 15777849 DOI: 10.1016/J.Bbamcr.2004.09.009  0.687
2005 Anand P, Gruppuso PA. The regulation of hepatic protein synthesis during fasting in the rat. The Journal of Biological Chemistry. 280: 16427-36. PMID 15716276 DOI: 10.1074/Jbc.M410576200  0.621
2005 Gruppuso PA, Boylan JM, Anand P, Bienieki TC. Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. Pediatric Research. 57: 185-91. PMID 15611345 DOI: 10.1203/01.Pdr.0000151646.55587.0F  0.676
2004 Phornphutkul C, Wu KY, Yang X, Chen Q, Gruppuso PA. Insulin-like growth factor-I signaling is modified during chondrocyte differentiation. The Journal of Endocrinology. 183: 477-86. PMID 15590974 DOI: 10.1677/Joe.1.05873  0.358
2004 Giannone PJ, Abu Dayyeh BK, Bienieki TC, Wands JR, Gruppuso PA. Targeted hepatic overexpression of human IRS-1: postnatal effects in the developing mouse. Biochimica Et Biophysica Acta. 1672: 112-9. PMID 15110093 DOI: 10.1016/J.Bbagen.2004.03.003  0.42
2004 Sanchez-Esteban J, Wang Y, Gruppuso PA, Rubin LP. Mechanical stretch induces fetal type II cell differentiation via an epidermal growth factor receptor-extracellular-regulated protein kinase signaling pathway. American Journal of Respiratory Cell and Molecular Biology. 30: 76-83. PMID 12829451 DOI: 10.1165/Rcmb.2003-0121Oc  0.376
2003 Khamzina L, Gruppuso PA, Wands JR. Insulin signaling through insulin receptor substrate 1 and 2 in normal liver development. Gastroenterology. 125: 572-85. PMID 12891559 DOI: 10.1016/S0016-5085(03)00893-X  0.382
2002 Boylan JM, Gruppuso PA. Insulin receptor substrate-1 is present in hepatocyte nuclei from intact rats. Endocrinology. 143: 4178-83. PMID 12399410 DOI: 10.1210/En.2002-220321  0.403
2002 Anand P, Boylan JM, Ou Y, Gruppuso PA. Insulin signaling during perinatal liver development in the rat. American Journal of Physiology. Endocrinology and Metabolism. 283: E844-52. PMID 12217903 DOI: 10.1152/Ajpendo.00111.2002  0.644
2001 Boylan JM, Anand P, Gruppuso PA. Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. The Journal of Biological Chemistry. 276: 44457-63. PMID 11574531 DOI: 10.1074/Jbc.M103457200  0.679
2001 Tseng YT, Kopel R, Stabila JP, McGonnigal BG, Nguyen TT, Gruppuso PA, Padbury JF. Beta-adrenergic receptors (betaAR) regulate cardiomyocyte proliferation during early postnatal life. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1921-6. PMID 11532972 DOI: 10.1096/Fj.01-0151Com  0.396
2001 Morin MJ, Karr SM, Faris RA, Gruppuso PA. Developmental variability in expression and regulation of inducible nitric oxide synthase in rat intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G552-9. PMID 11447036 DOI: 10.1152/Ajpgi.2001.281.2.G552  0.305
2000 Gruppuso PA, Boylan JM, Vaslet CA. Identification of candidate growth-regulating genes that are overexpressed in late gestation fetal liver in the rat. Biochimica Et Biophysica Acta. 1494: 242-7. PMID 11121581 DOI: 10.1016/S0167-4781(00)00244-X  0.477
2000 Awad MM, Sanders JA, Gruppuso PA. A potential role for p15(Ink4b) and p57(Kip2) in liver development. Febs Letters. 483: 160-4. PMID 11042273 DOI: 10.1016/S0014-5793(00)02108-6  0.727
2000 Phornphutkul C, Frick GP, Goodman HM, Berry SA, Gruppuso PA. Hepatic growth hormone signaling in the late gestation fetal rat. Endocrinology. 141: 3527-33. PMID 11014205 DOI: 10.1210/Endo.141.10.7702  0.461
2000 Awad MM, Enslen H, Boylan JM, Davis RJ, Gruppuso PA. Growth regulation via p38 mitogen-activated protein kinase in developing liver. The Journal of Biological Chemistry. 275: 38716-21. PMID 10995779 DOI: 10.1074/Jbc.M008040200  0.668
2000 Boney CM, Gruppuso PA, Faris RA, Frackelton AR. The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 805-13. PMID 10847583 DOI: 10.1210/Mend.14.6.0487  0.349
2000 Gruppuso PA, Boylan JM. Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKK. Febs Letters. 466: 200-4. PMID 10648842 DOI: 10.1016/S0014-5793(99)01792-5  0.403
1999 Gruppuso PA, Bienieki TC, Faris RA. The relationship between differentiation and proliferation in late gestation fetal rat hepatocytes. Pediatric Research. 46: 14-9. PMID 10400128 DOI: 10.1203/00006450-199907000-00003  0.414
1999 Gruppuso PA, Boylan JM. Late Gestation Fetal Rat Hepatocyte Proliferation Is Independent of p70 S6 Kinase Mitogenic Signaling: Implications for the Role of Growth Factors in Fetal Liver Development Pediatric Research. 45: 52A-52A. DOI: 10.1203/00006450-199904020-00314  0.453
1999 Gruppuso PA. Candidate Growth Regulating Genes in Late Gestation Fetal Rat Hepatocytes (FH): Identification by Subtractive Hybridization (SH) Pediatric Research. 45: 52A-52A. DOI: 10.1203/00006450-199904020-00313  0.381
1998 Boney CM, Smith RM, Gruppuso PA. Modulation of insulin-like growth factor I mitogenic signaling in 3T3-L1 preadipocyte differentiation. Endocrinology. 139: 1638-44. PMID 9528944 DOI: 10.1210/Endo.139.4.5920  0.337
1998 Boylan JM, Gruppuso PA. Uncoupling of hepatic, epidermal growth factor-mediated mitogen-activated protein kinase activation in the fetal rat. The Journal of Biological Chemistry. 273: 3784-90. PMID 9452512 DOI: 10.1074/Jbc.273.6.3784  0.409
1998 Gruppuso PA, Awad M, Boylan JM, Enslen H, Davis RJ. Signaling and Cell Cycle Regulation During Liver Development in the Rat• 269 Pediatric Research. 43: 48-48. DOI: 10.1203/00006450-199804001-00290  0.48
1997 Gruppuso PA, Awad M, Bienieki TC, Boylan JM, Fernando S, Faris RA. Modulation of mitogen-independent hepatocyte proliferation during the perinatal period in the rat. In Vitro Cellular & Developmental Biology. Animal. 33: 562-8. PMID 9282317 DOI: 10.1007/S11626-997-0099-X  0.656
1997 Leeds P, Kren BT, Boylan JM, Betz NA, Steer CJ, Gruppuso PA, Ross J. Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro. Oncogene. 14: 1279-86. PMID 9178888 DOI: 10.1038/Sj.Onc.1201093  0.407
1997 Gruppuso PA, Boylan JM. A Novel Mechanism for Uncoupling of the Hepatic Ras/Mitogen ActivatedProtein Kinase (MAPK) Signaling Pathway in the Developing Rat. • 385 Pediatric Research. 41: 67-67. DOI: 10.1203/00006450-199704001-00405  0.353
1997 Gruppuso PA. The Relationship Between Proliferation and Differentiation in Fetal Rat Hepatocytes 257 Pediatric Research. 41: 45-45. DOI: 10.1203/00006450-199704001-00277  0.354
1997 Morin MJ, Faris RA, Gruppuso PA. Inducible Nitric Oxide Synthase (iNOS) in the Rat Intestine: An Immunohistochemical Study of Ontogeny in an Animal Model of Sepsis † 205 Pediatric Research. 41: 37-37. DOI: 10.1203/00006450-199704001-00225  0.317
1996 Lipeski LE, Boylan JM, Gruppuso PA. A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor alpha and epidermal growth factor in cultured fetal rat hepatocytes. Biochemistry and Molecular Biology International. 39: 975-83. PMID 8866014 DOI: 10.1080/15216549600201122  0.33
1996 Boney CM, Fiedorek FT, Paul SR, Gruppuso PA. Regulation of preadipocyte factor-1 gene expression during 3T3-L1 cell differentiation. Endocrinology. 137: 2923-8. PMID 8770915 DOI: 10.1210/Endo.137.7.8770915  0.325
1996 Goto M, Chen H, Gruppuso PA, Zeller WP. TNFα SIGNALLING IS ALTERED BY PREVIOUS ENDOTOXIN EXPOSURE IN 10 DAY OLD RAT HEPATOCYTES. 1845 Pediatric Research. 39: 310-310. DOI: 10.1203/00006450-199604001-01869  0.314
1996 Mustafa-Kutana S, Boylan JM, Gruppuso PA. SELECTIVE HEPATIC INSULIN RESISTANCE IN GROWTH RETARDED FETAL RATS: STUDIES ON INSULIN RECEPTOR SUBSTRATE-1 (IRS-1) CONTENT AND TYROSINE PHOSPHORYLATION. • 551 Pediatric Research. 39: 94-94. DOI: 10.1203/00006450-199604001-00572  0.38
1996 Gruppuso PA, Awad M, Bienieki TC, Boylan JM, Fernando S. STUDIES ON THE ONTOGENY OF FETAL HEPATOCYTE (FH) PROLIFERATION DURING LATE GESTATION IN THE RAT. † 341 Pediatric Research. 39: 59-59. DOI: 10.1203/00006450-199604001-00361  0.373
1995 Gruppuso PA, Boylan JM. Developmental changes in the activity and cellular localization of hepatic casein kinase II in the rat. Journal of Cellular Biochemistry. 58: 65-72. PMID 7642724 DOI: 10.1002/Jcb.240580109  0.443
1994 Gruppuso PA, Boylan JM, Bienieki TC, Curran TR. Evidence for a direct hepatotrophic role for insulin in the fetal rat: implications for the impaired hepatic growth seen in fetal growth retardation. Endocrinology. 134: 769-75. PMID 8299572 DOI: 10.1210/Endo.134.2.8299572  0.375
1994 Boylan JM, Gruppuso PA. In vitro and in vivo regulation of hepatic mitogen-activated protein kinases in fetal rats. The American Journal of Physiology. 267: G1078-86. PMID 7810654 DOI: 10.1152/Ajpgi.1994.267.6.G1078  0.396
1993 Curran TR, Bahner RI, Oh W, Gruppuso PA. Mitogen-independent DNA synthesis by fetal rat hepatocytes in primary culture. Experimental Cell Research. 209: 53-7. PMID 8224006 DOI: 10.1006/Excr.1993.1284  0.347
1992 Gruppuso PA, Boylan JM, Carter PA, Madden JA, Raven T. Hepatic insulin and EGF receptor phosphorylation and dephosphorylation in fetal rats. The American Journal of Physiology. 262: E6-13. PMID 1733252 DOI: 10.1152/Ajpendo.1992.262.1.E6  0.362
1992 Boylan JM, Brautigan DL, Madden J, Raven T, Ellis L, Gruppuso PA. Differential regulation of multiple hepatic protein tyrosine phosphatases in alloxan diabetic rats. The Journal of Clinical Investigation. 90: 174-9. PMID 1321840 DOI: 10.1172/Jci115833  0.35
1991 Gruppuso PA, Walker TD, Carter PA. Ontogeny of hepatic type i insulin-like growth factor receptors in the rat Pediatric Research. 29: 226-230. PMID 1851980 DOI: 10.1203/00006450-199103000-00002  0.394
1991 Gruppuso PA, Boylan JM, Smiley BL, Fallon RJ, Brautigan DL. Hepatic protein tyrosine phosphatases in the rat. The Biochemical Journal. 274: 361-7. PMID 1848753 DOI: 10.1042/Bj2740361  0.348
1991 Gruppuso PA, Curran TR, Mead JE, Fausto N, Oh W. Fetal growth factors as determinants of intrauterine hepatic growth Diabetes. 40: 51-55. PMID 1660827 DOI: 10.2337/Diab.40.2.S51  0.387
1990 Fausto N, Mead JE, Gruppuso PA, Braun L. TGF-β in liver development, regeneration, and carcinogenesis Annals of the New York Academy of Sciences. 593: 231-242. PMID 2165377 DOI: 10.1111/J.1749-6632.1990.Tb16115.X  0.328
1990 Gruppuso PA. Hepatic protein Kinase-C and protein phosphatase type-2A in the fetal rat Pediatric Research. 27: 599-603. PMID 2162516 DOI: 10.1203/00006450-199006000-00014  0.411
1990 Gruppuso PA, Boylan JM, Posner BI, Faure R, Brautigan DL. Hepatic protein phosphotyrosine phosphatase. Dephosphorylation of insulin and epidermal growth factor receptors in normal and alloxan diabetic rats. The Journal of Clinical Investigation. 85: 1754-60. PMID 2161429 DOI: 10.1172/Jci114632  0.359
1989 Gruppuso PA. Effects of fetal hypoinsulinemia on fetal hepatic insulin binding in the rat Bba - Molecular Cell Research. 1010: 270-273. PMID 2643442 DOI: 10.1016/0167-4889(89)90172-9  0.346
1989 Gruppuso PA. Expression of hepatic transforming growth factor receptors during late gestation in the fetal rat Endocrinology. 125: 3037-3043. PMID 2555136 DOI: 10.1210/Endo-125-6-3037  0.375
1989 Gruppuso PA, Brautigan DL. Induction of hepatic glycogenesis in the fetal rat American Journal of Physiology - Endocrinology and Metabolism. 256: 19/1. PMID 2492154 DOI: 10.1152/Ajpendo.1989.256.1.E49  0.43
1987 Gruppuso PA, Brautigan DL, Schwartz R. INTRINSIC REGULATION OF GLYCOGEN PARTICLES: LIVER v. SKELETAL MUSCLE Pediatric Research. 21: 342A-342A. DOI: 10.1203/00006450-198704010-01047  0.33
1985 Domenech M, Gruppuso PA, Susa JB, Schwartz R. Induction in utero of hepatic glucose-6-phosphatase by fetal hypoinsulinemia Neonatology. 47: 92-98. PMID 2983786 DOI: 10.1159/000242096  0.373
1984 Susa JB, Gruppuso PA, Widness JA, Domenech M, Clemons GK, Sehgal P, Schwartz R. Chronic hyperinsulinemia in the fetal rhesus monkey: Effects of physiologic hyperinsulinemia on fetal substrates, hormones, and hepatic enzymes American Journal of Obstetrics and Gynecology. 150: 415-420. PMID 6385723 DOI: 10.1016/S0002-9378(84)80150-7  0.307
1983 Gruppuso PA, Susa JB, Domenech M, Cha CJ, Schwartz R. Chronic hyperglucagonemia in rats: Effects on insulin, substrates, and hepatic enzymes of intermediary metabolism Metabolism. 32: 911-918. PMID 6350815 DOI: 10.1016/0026-0495(83)90206-8  0.345
1981 Gruppuso PA, Migliori R, Susa JB, Schwartz R. Chronic maternal hyperinsulinemia and hypoglycemia. A model for experimental intrauterine growth retardation. Biology of the Neonate. 40: 113-20. PMID 7025925 DOI: 10.1159/000241479  0.314
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