Wenyi Wei, Ph.D. - Publications

Affiliations: 
2002 Brown University, Providence, RI 

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ke S, Dang F, Wang L, Chen JY, Naik MT, Li W, Thavamani A, Kim N, Naik NM, Sui H, Tang W, Qiu C, Koikawa K, Batalini F, Stern Gatof E, ... ... Wei W, et al. Reciprocal antagonism of PIN1-APC/C governs mitotic protein stability and cell cycle entry. Nature Communications. 15: 3220. PMID 38622115 DOI: 10.1038/s41467-024-47427-w  0.332
2024 Ma J, Li L, Ma B, Liu T, Wang Z, Ye Q, Peng Y, Wang B, Chen Y, Xu S, Wang K, Dang F, Wang X, Zeng Z, Jian Y, ... ... Wei W, et al. MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation. Nature Communications. 15: 1871. PMID 38424044 DOI: 10.1038/s41467-024-45796-w  0.305
2023 Wang Z, Liu J, Chen H, Qiu X, Xie L, Kaniskan HÜ, Chen X, Jin J, Wei W. Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society. PMID 37141574 DOI: 10.1021/jacs.3c02783  0.318
2023 Rezaeian AH, Phan LM, Zhou X, Wei W, Inuzuka H. Pharmacological inhibition of the SKP2/p300 signaling axis restricts castration-resistant prostate cancer. Neoplasia (New York, N.Y.). 38: 100890. PMID 36871351 DOI: 10.1016/j.neo.2023.100890  0.33
2022 Rezaeian AH, Inuzuka H, Wei W. Insights into the aberrant CDK4/6 signaling pathway as a therapeutic target in tumorigenesis. Advances in Protein Chemistry and Structural Biology. 135: 179-201. PMID 37061331 DOI: 10.1016/bs.apcsb.2022.11.009  0.318
2022 Wu X, Xie W, Xie W, Wei W, Guo J. Beyond controlling cell size: functional analyses of S6K in tumorigenesis. Cell Death & Disease. 13: 646. PMID 35879299 DOI: 10.1038/s41419-022-05081-4  0.348
2022 Dai X, Zhang X, Yin Q, Hu J, Guo J, Gao Y, Snell AH, Inuzuka H, Wan L, Wei W. Acetylation-dependent regulation of BRAF oncogenic function. Cell Reports. 38: 110250. PMID 35045286 DOI: 10.1016/j.celrep.2021.110250  0.304
2021 Kishikawa T, Higuchi H, Wang L, Panch N, Maymi V, Best S, Lee S, Notoya G, Toker A, Matesic LE, Wulf GM, Wei W, Otsuka M, Koike K, Clohessy JG, et al. WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models. The Journal of Clinical Investigation. 131. PMID 34907909 DOI: 10.1172/JCI140436  0.304
2021 Shimizu K, Gi M, Suzuki S, North BJ, Watahiki A, Fukumoto S, Asara JM, Tokunaga F, Wei W, Inuzuka H. Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Cell Reports. 37: 109988. PMID 34758305 DOI: 10.1016/j.celrep.2021.109988  0.348
2021 Liu J, Peng Y, Wei W. Cell cycle on the crossroad of tumorigenesis and cancer therapy. Trends in Cell Biology. PMID 34304958 DOI: 10.1016/j.tcb.2021.07.001  0.313
2021 Zhang W, Li L, Cai L, Liang Y, Xu J, Liu Y, Zhou L, Ding C, Zhang Y, Zhao H, Qin J, Shao Z, Wei W, Jia L. Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the  receptor protein of CRL2 complex. Cell Death and Differentiation. PMID 33504946 DOI: 10.1038/s41418-020-00724-5  0.349
2020 Dang F, Nie L, Wei W. Ubiquitin signaling in cell cycle control and tumorigenesis. Cell Death and Differentiation. PMID 33130827 DOI: 10.1038/s41418-020-00648-0  0.37
2020 Hoshikawa S, Shimizu K, Watahiki A, Chiba M, Saito K, Wei W, Fukumoto S, Inuzuka H. Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32931083 DOI: 10.1096/Fj.202001340R  0.44
2020 Zhang S, Shen Y, Li H, Bi C, Sun Y, Xiong X, Wei W, Sun Y. The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance. Cell Reports. 32: 108102. PMID 32905768 DOI: 10.1016/J.Celrep.2020.108102  0.338
2020 Liu J, Peng Y, Shi L, Wan L, Inuzuka H, Long J, Guo J, Zhang J, Yuan M, Zhang S, Wang X, Gao J, Dai X, Furumoto S, Jia L, ... ... Wei W, et al. Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell Research. PMID 32859994 DOI: 10.1038/S41422-020-00406-4  0.303
2020 Wang M, Liu J, Zhao Y, He R, Xu X, Guo X, Li X, Xu S, Miao J, Guo J, Zhang H, Gong J, Zhu F, Tian R, Shi C, ... ... Wei W, et al. Upregulation of METTL14 mediates the elevation of PERP mRNA N adenosine methylation promoting the growth and metastasis of pancreatic cancer. Molecular Cancer. 19: 130. PMID 32843065 DOI: 10.1186/S12943-020-01249-8  0.3
2020 Liu J, Peng Y, Shi L, Wan L, Inuzuka H, Long J, Guo J, Zhang J, Yuan M, Zhang S, Wang X, Gao J, Dai X, Furumoto S, Jia L, ... ... Wei W, et al. Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell Research. PMID 32669607 DOI: 10.1038/S41422-020-0372-Z  0.391
2020 Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. The New England Journal of Medicine. 382: 2103-2116. PMID 32459922 DOI: 10.1056/Nejmoa1914919  0.332
2020 Wang P, Dai X, Jiang W, Li Y, Wei W. RBR E3 ubiquitin ligases in tumorigenesis. Seminars in Cancer Biology. PMID 32442483 DOI: 10.1016/J.Semcancer.2020.05.002  0.358
2020 Wang Z, Song Y, Ye M, Dai X, Zhu X, Wei W. The diverse roles of SPOP in prostate cancer and kidney cancer. Nature Reviews. Urology. PMID 32355326 DOI: 10.1038/S41585-020-0314-Z  0.355
2020 Li L, Zhang W, Liu Y, Liu X, Cai L, Kang J, Zhang Y, Chen W, Dong C, Zhang Y, Wang M, Wei W, Jia L. The CRL3 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration. Signal Transduction and Targeted Therapy. 5: 42. PMID 32327643 DOI: 10.1038/S41392-020-0140-Z  0.436
2020 Deng L, Meng T, Chen L, Wei W, Wang P. The role of ubiquitination in tumorigenesis and targeted drug discovery. Signal Transduction and Targeted Therapy. 5: 11. PMID 32296023 DOI: 10.1038/S41392-020-0107-0  0.442
2020 Deng L, Meng T, Chen L, Wei W, Wang P. The role of ubiquitination in tumorigenesis and targeted drug discovery. Signal Transduction and Targeted Therapy. 5: 11. PMID 32140262 DOI: 10.1038/s41392-020-0107-0  0.334
2020 Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, Lin Q, Zhang T, Gray N, Kaniskan HÜ, Jin J, Wei W. Light-induced control of protein destruction by opto-PROTAC. Science Advances. 6: eaay5154. PMID 32128407 DOI: 10.1126/Sciadv.Aay5154  0.308
2020 Liu J, Ma J, Liu Y, Xia J, Li Y, Wang ZP, Wei W. PROTACs: a novel strategy for cancer therapy. Seminars in Cancer Biology. PMID 32058059 DOI: 10.1016/J.Semcancer.2020.02.006  0.369
2020 Chen WL, Jin X, Wang M, Liu D, Luo Q, Tian H, Cai L, Meng L, Bi R, Wang L, Xie X, Yu G, Li L, Dong C, Cai Q, ... ... Wei W, et al. GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling. Jci Insight. 5. PMID 32051337 DOI: 10.1172/Jci.Insight.131596  0.341
2020 Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, ... ... Wei W, et al. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature Cell Biology. PMID 32015438 DOI: 10.1038/S41556-020-0463-6  0.383
2020 Liu J, Peng Y, Zhang J, Long J, Liu J, Wei W. Targeting SCF E3 Ligases for Cancer Therapies. Advances in Experimental Medicine and Biology. 1217: 123-146. PMID 31898226 DOI: 10.1007/978-981-15-1025-0_9  0.419
2019 Cheng J, Guo J, North BJ, Wang B, Cui CP, Li H, Tao K, Zhang L, Wei W. Functional analysis of deubiquitylating enzymes in tumorigenesis and development. Biochimica Et Biophysica Acta. Reviews On Cancer. 188312. PMID 31449841 DOI: 10.1016/J.Bbcan.2019.188312  0.395
2019 Kuai X, Li L, Chen R, Wang K, Chen M, Cui B, Zhang Y, Li J, Zhu H, Zhou H, Huang J, Qin J, Wang Z, Wei W, Gao D. SCFFBXW7/GSK3β-mediated GFI1 degradation suppresses gastric cancer cell proliferation. Cancer Research. PMID 31289136 DOI: 10.1158/0008-5472.Can-18-4032  0.379
2019 Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discovery. PMID 31217297 DOI: 10.1158/2159-8290.Cd-18-0083  0.386
2019 Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, ... ... Wei W, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.). 364. PMID 31097636 DOI: 10.1126/Science.Aau0159  0.401
2019 Guo J, Wei W. Fine-tuning AKT kinase activity through direct lysine methylation. Cell Cycle (Georgetown, Tex.). 1-6. PMID 31050579 DOI: 10.1080/15384101.2019.1609832  0.364
2019 Kim W, Cho YS, Wang X, Park O, Ma X, Kim H, Gan W, Jho EH, Cha B, Jeung YJ, Zhang L, Gao B, Wei W, Jiang J, Chung KS, et al. Hippo signaling is intrinsically regulated during cell cycle progression by APC/C. Proceedings of the National Academy of Sciences of the United States of America. PMID 31000600 DOI: 10.1073/Pnas.1821370116  0.443
2019 Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, ... ... Wei W, et al. Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nature Cell Biology. PMID 30783264 DOI: 10.1038/S41556-019-0280-Y  0.366
2019 Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nature Cell Biology. PMID 30692625 DOI: 10.1038/S41556-018-0261-6  0.394
2019 Fujii M, Nakayama S, Akanuma N, Pan G, Kobayashi IS, Takei H, Shimizu K, Ando M, Heo E, Gergis C, Inuzuka H, Wei W, Costa DB, Kobayashi SS. Abstract 320: Met/Ror1-β-catenin-Bcl-xL axis contributes to the emergence of drug-tolerant cells that evolve into resistant tumors inEGFR-mutant lung cancer Cancer Research. 79: 320-320. DOI: 10.1158/1538-7445.Sabcs18-320  0.38
2018 Cheng J, Guo J, North BJ, Tao K, Zhou P, Wei W. The emerging role for Cullin 4 family of E3 ligases in tumorigenesis. Biochimica Et Biophysica Acta. Reviews On Cancer. PMID 30602127 DOI: 10.1016/J.Bbcan.2018.11.007  0.372
2018 Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, ... ... Wei W, et al. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Developmental Cell. PMID 30595538 DOI: 10.1016/J.Devcel.2018.11.035  0.396
2018 Liu S, Zhang G, Guo J, Chen X, Lei J, Ze K, Dong L, Dai X, Gao Y, Song D, Ecker B, Yang R, Feltcher C, Peng K, Feng C, ... ... Wei W, et al. Loss of Phd2 cooperates with BRAF to drive melanomagenesis. Nature Communications. 9: 5426. PMID 30575721 DOI: 10.1038/S41467-018-07126-9  0.381
2018 Ma Y, Cui D, Xiong X, Inuzuka H, Wei W, Sun Y, North BJ, Zhao Y. SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation. Molecular Oncology. PMID 30428154 DOI: 10.1002/1878-0261.12403  0.369
2018 Cui CP, Zhang Y, Wang C, Yuan F, Li H, Yao Y, Chen Y, Li C, Wei W, Liu CH, He F, Liu Y, Zhang L. Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation. Nature Communications. 9: 4648. PMID 30405104 DOI: 10.1038/S41467-018-07025-Z  0.342
2018 Huang LY, Zhao J, Chen H, Wan L, Inuzuka H, Guo J, Fu X, Zhai Y, Lu Z, Wang X, Han ZG, Sun Y, Wei W. SCF-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nature Communications. 9: 3569. PMID 30177679 DOI: 10.1038/S41467-018-06038-Y  0.366
2018 Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L. Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nature Communications. 9: 2464. PMID 29942010 DOI: 10.1038/S41467-018-04815-3  0.356
2018 Zhou W, Xu J, Tan M, Li H, Li H, Wei W, Sun Y. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F. Molecular Cell. 70: 1008-1024.e6. PMID 29932898 DOI: 10.1016/J.Molcel.2018.06.002  0.317
2018 Zhang J, Guo J, Qin X, Wang B, Zhang L, Wang Y, Gan W, Pandofi PP, Chen W, Wei W. The p85 isoform of the kinase S6K1 functions as a secreted oncoprotein to facilitate cell migration and tumor growth. Science Signaling. 11. PMID 29588411 DOI: 10.1126/Scisignal.Aao1052  0.467
2018 Clement E, Inuzuka H, Nihira NT, Wei W, Toker A. Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors. Science Signaling. 11. PMID 29535262 DOI: 10.1126/Scisignal.Aao3810  0.426
2018 Shimizu K, Nihira NT, Inuzuka H, Wei W. Physiological functions of FBW7 in cancer and metabolism. Cellular Signalling. PMID 29474981 DOI: 10.1016/J.Cellsig.2018.02.009  0.415
2018 Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, ... ... Wei W, et al. The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nature Cell Biology. PMID 29403037 DOI: 10.1038/S41556-017-0033-8  0.38
2018 Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, ... ... Wei W, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Molecular Cell. 69: 279-291.e5. PMID 29351847 DOI: 10.1016/J.Molcel.2017.12.024  0.429
2018 Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, ... ... Wei W, et al. The protective role of DOT1L in UV-induced melanomagenesis. Nature Communications. 9: 259. PMID 29343685 DOI: 10.1038/S41467-017-02687-7  0.327
2018 Chen M, Wan L, Zhang J, Zhang J, Mendez L, Clohessy JG, Berry K, Victor J, Yin Q, Zhu Y, Wei W, Pandolfi PP. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nature Communications. 9: 159. PMID 29335436 DOI: 10.1038/S41467-017-02272-Y  0.422
2017 Cheng J, Guo J, Wang Z, North BJ, Tao K, Dai X, Wei W. Functional analysis of Cullin 3 E3 ligases in tumorigenesis. Biochimica Et Biophysica Acta. PMID 29128526 DOI: 10.1016/J.Bbcan.2017.11.001  0.42
2017 Dai X, Wang Z, Wei W. SPOP-mediated degradation of BRD4 dictates cellular sensitivity to BET inhibitors. Cell Cycle (Georgetown, Tex.). 0. PMID 29108467 DOI: 10.1080/15384101.2017.1388973  0.361
2017 Wang D, Ma L, Wang B, Liu J, Wei W. E3 ubiquitin ligases in cancer and implications for therapies. Cancer Metastasis Reviews. PMID 29043469 DOI: 10.1007/S10555-017-9703-Z  0.349
2017 Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, ... ... Wei W, et al. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature Medicine. PMID 28805820 DOI: 10.1038/Nm.4378  0.389
2017 Takada M, Zhang W, Suzuki A, Kuroda T, Yu Z, Inuzuka H, Gao D, Wan L, Zhuang M, Hu L, Zhai B, Fry C, Bloom K, Li G, Karpen G, ... Wei W, et al. FBW7 loss promotes chromosomal instability and tumorigenesis via Cyclin E1/CDK2-mediated phosphorylation of CENP-A. Cancer Research. PMID 28760857 DOI: 10.1158/0008-5472.Can-17-1240  0.397
2017 Guo J, Cheng J, North BJ, Wei W. Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology. Biochimica Et Biophysica Acta. PMID 28694093 DOI: 10.1016/J.Bbcan.2017.07.001  0.301
2017 Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, ... Wei W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. PMID 28489822 DOI: 10.1038/Nature22344  0.432
2017 Zhang J, Liu J, Wei W. "FEM1"nism controls SLBP stability during cell cycle. Cell Cycle (Georgetown, Tex.). 0. PMID 28324668 DOI: 10.1080/15384101.2017.1302226  0.314
2017 Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, Wan L, Zhang Z, Zhang C, Qin X, Xiao M, Ye D, Liu Y, Han Z, Wang S, ... ... Wei W, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. The Embo Journal. PMID 28320739 DOI: 10.15252/Embj.201694058  0.417
2017 Jansen VM, Bhola NE, Bauer JA, Formisano L, Lee KM, Hutchinson KE, Witkiewicz AK, Moore PD, Estrada MV, Sanchez V, Ericsson PG, Sanders M, Pohlmann PR, Pishvaian MJ, Riddle DA, ... Wei W, et al. Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer. Cancer Research. PMID 28249908 DOI: 10.1158/0008-5472.Can-16-2653  0.443
2017 Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W. Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. Science Signaling. 10. PMID 28196907 DOI: 10.1126/Scisignal.Aai8026  0.441
2017 Liu L, Michowski W, Inuzuka H, Shimizu K, Nihira NT, Chick JM, Li N, Geng Y, Meng AY, Ordureau A, Kołodziejczyk A, Ligon KL, Bronson RT, Polyak K, Harper JW, ... ... Wei W, et al. G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells. Nature Cell Biology. PMID 28192421 DOI: 10.1038/Ncb3474  0.41
2017 Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, ... ... Wei W, et al. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discovery. PMID 28174173 DOI: 10.1158/2159-8290.Cd-16-0647  0.453
2017 Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, Hu G, Guo J. Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Letters. PMID 28089830 DOI: 10.1016/J.Canlet.2017.01.003  0.343
2017 Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, ... ... Wei W, et al. The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. Science Signaling. 10. PMID 28049764 DOI: 10.1126/Scisignal.Aah4117  0.322
2016 Liu X, Yao Y, Ding H, Han C, Chen Y, Zhang Y, Wang C, Zhang X, Zhang Y, Zhai Y, Wang P, Wei W, Zhang J, Zhang L. USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency. Signal Transduction and Targeted Therapy. 1: 16024. PMID 29263902 DOI: 10.1038/Sigtrans.2016.24  0.346
2016 Wu F, Dai X, Gan W, Wan L, Li M, Mitsiades N, Wei W, Ding Q, Zhang J. Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Letters. PMID 27780719 DOI: 10.1016/J.Canlet.2016.10.021  0.379
2016 Cheng J, Zhang T, Ji H, Tao K, Guo J, Wei W. Functional characterization of AMP-activated protein kinase signaling in tumorigenesis. Biochimica Et Biophysica Acta. PMID 27681874 DOI: 10.1016/J.Bbcan.2016.09.006  0.397
2016 Zurlo G, Guo J, Takada M, Wei W, Zhang Q. New Insights into Protein Hydroxylation and Its Important Role in Human Diseases. Biochimica Et Biophysica Acta. PMID 27663420 DOI: 10.1016/J.Bbcan.2016.09.004  0.375
2016 Zheng N, Dai X, Wang Z, Wei W. A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle. Cell Cycle (Georgetown, Tex.). 0. PMID 27649746 DOI: 10.1080/15384101.2016.1234552  0.372
2016 Zhou W, Xu J, Li H, Xu M, Chen ZJ, Wei W, Pan ZQ, Sun Y. Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27591266 DOI: 10.1158/1078-0432.Ccr-16-1585  0.372
2016 Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang J, Zhang L, Yuan M, Novak J, Cheng JQ, Toker A, Signoretti S, Zhang Q, ... ... Wei W, et al. pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. Science (New York, N.Y.). 353: 929-32. PMID 27563096 DOI: 10.1126/Science.Aad5755  0.436
2016 Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discovery. 2: 15044. PMID 27462441 DOI: 10.1038/Celldisc.2015.44  0.418
2016 Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Molecular Cell. PMID 27237051 DOI: 10.1016/J.Molcel.2016.04.023  0.459
2016 Zheng N, Zhou Q, Wang Z, Wei W. Recent advances in SCF ubiquitin ligase complex: Clinical implications. Biochimica Et Biophysica Acta. PMID 27156687 DOI: 10.1016/J.Bbcan.2016.05.001  0.337
2016 Shao R, Liu J, Yan G, Zhang J, Han Y, Guo J, Xu Z, Yuan Z, Liu J, Malumbres M, Wan L, Wei W, Zou W. Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid. Cell Research. PMID 27126000 DOI: 10.1038/Cr.2016.51  0.345
2016 Zheng N, Wang Z, Wei W. Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins. The International Journal of Biochemistry & Cell Biology. PMID 26860958 DOI: 10.1016/J.Biocel.2016.02.005  0.385
2016 Qin X, Yan M, Zhang J, Wang X, Shen Z, Lv Z, Li Z, Wei W, Chen W. TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis. Scientific Reports. 6: 20587. PMID 26857387 DOI: 10.1038/Srep20587  0.369
2015 Wang Z, Dai X, Zhong J, Inuzuka H, Wan L, Li X, Wang L, Ye X, Sun L, Gao D, Zou L, Wei W. SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation. Nature Communications. 6: 10185. PMID 26666832 DOI: 10.1038/Ncomms10185  0.405
2015 Gan W, Dai X, Lunardi A, Li Z, Inuzuka H, Liu P, Varmeh S, Zhang J, Cheng L, Sun Y, Asara JM, Beck AH, Huang J, Pandolfi PP, Wei W. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Molecular Cell. PMID 26344095 DOI: 10.1016/J.Molcel.2015.07.026  0.37
2015 Cao J, Dai X, Wan L, Wang H, Zhang J, Goff PS, Sviderskaya EV, Xuan Z, Xu Z, Xu X, Hinds P, Flaherty KT, Faller DV, Goding CR, Wang Y, ... Wei W, et al. The E3 ligase APC/CCdh1 promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth. Science Signaling. 8: ra87. PMID 26329581 DOI: 10.1126/Scisignal.Aab1995  0.413
2015 Liu P, Gan W, Chin YR, Ogura K, Guo J, Zhang J, Wang B, Blenis J, Cantley LC, Toker A, Su B, Wei W. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discovery. 5: 1194-209. PMID 26293922 DOI: 10.1158/2159-8290.Cd-15-0460  0.412
2015 Yuan L, Lv Y, Li H, Gao H, Song S, Zhang Y, Xing G, Kong X, Wang L, Li Y, Zhou T, Gao D, Xiao ZX, Yin Y, Wei W, et al. Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis. Nature Cell Biology. 17: 1169-81. PMID 26280536 DOI: 10.1038/Ncb3218  0.42
2015 Gan W, Liu P, Wei W. Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF. Nucleus (Austin, Tex.). 6: 261-5. PMID 26225792 DOI: 10.1080/19491034.2015.1074365  0.403
2015 Gan W, Liu P, Wei W. Cell cycle status dictates effectiveness of rapamycin. Cell Cycle (Georgetown, Tex.). 1-2. PMID 26126171 DOI: 10.1080/15384101.2015.1060778  0.358
2015 Wang L, Zhang J, Wan L, Zhou X, Wang Z, Wei W. Targeting Cdc20 as a novel cancer therapeutic strategy. Pharmacology & Therapeutics. 151: 141-151. PMID 25850036 DOI: 10.1016/J.Pharmthera.2015.04.002  0.47
2015 Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W. Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Molecular Cell. 57: 648-61. PMID 25661488 DOI: 10.1016/J.Molcel.2015.01.005  0.364
2015 Su J, Yin X, Zhou X, Wei W, Wang Z. The functions of F-box proteins in regulating the epithelial to mesenchymal transition. Current Pharmaceutical Design. 21: 1311-7. PMID 25506894 DOI: 10.2174/1381612821666141211144203  0.358
2015 Liu J, Shaik S, Dai X, Wu Q, Zhou X, Wang Z, Wei W. Targeting the ubiquitin pathway for cancer treatment. Biochimica Et Biophysica Acta. 1855: 50-60. PMID 25481052 DOI: 10.1016/J.Bbcan.2014.11.005  0.409
2014 Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Molecular Cell. 56: 595-607. PMID 25458846 DOI: 10.1016/J.Molcel.2014.09.023  0.404
2014 Xu K, Liu P, Wei W. mTOR signaling in tumorigenesis. Biochimica Et Biophysica Acta. 1846: 638-54. PMID 25450580 DOI: 10.1016/J.Bbcan.2014.10.007  0.418
2014 Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, Liu L, Wang H, King B, Shaik S, Gutierrez A, Ordureau A, Otto T, Kreslavsky T, Baitsch L, ... ... Wei W, et al. Cyclin C is a haploinsufficient tumour suppressor. Nature Cell Biology. 16: 1080-91. PMID 25344755 DOI: 10.1038/Ncb3046  0.37
2014 Ye X, Wang L, Shang B, Wang Z, Wei W. NEDD4: a promising target for cancer therapy. Current Cancer Drug Targets. 14: 549-56. PMID 25088038 DOI: 10.2174/1568009614666140725092430  0.412
2014 Wu X, Fukushima H, North BJ, Nagaoka Y, Nagashima K, Deng F, Okabe K, Inuzuka H, Wei W. SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination. Oncotarget. 5: 4211-21. PMID 24961988 DOI: 10.18632/Oncotarget.1971  0.407
2014 Liu P, Wang Z, Wei W. Phosphorylation of Akt at the C-terminal tail triggers Akt activation. Cell Cycle (Georgetown, Tex.). 13: 2162-4. PMID 24933731 DOI: 10.4161/Cc.29584  0.409
2014 Wang L, Ye X, Liu Y, Wei W, Wang Z. Aberrant regulation of FBW7 in cancer. Oncotarget. 5: 2000-15. PMID 24899581 DOI: 10.18632/Oncotarget.1859  0.329
2014 Wan L, Tan M, Yang J, Inuzuka H, Dai X, Wu T, Liu J, Shaik S, Chen G, Deng J, Malumbres M, Letai A, Kirschner MW, Sun Y, Wei W. APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction. Developmental Cell. 29: 377-91. PMID 24871945 DOI: 10.1016/J.Devcel.2014.04.022  0.427
2014 Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, Ito K, Turka LA, Beck AH, ... ... Wei W, et al. Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function. Cell. 157: 595-610. PMID 24766807 DOI: 10.1016/J.Cell.2014.03.027  0.409
2014 Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, ... ... Wei W, et al. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 508: 541-5. PMID 24670654 DOI: 10.1038/Nature13079  0.458
2014 Liu J, Wan L, Liu P, Inuzuka H, Liu J, Wang Z, Wei W. SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway. Oncotarget. 5: 1026-37. PMID 24657926 DOI: 10.18632/Oncotarget.1675  0.467
2014 Zhang J, Wan L, Dai X, Sun Y, Wei W. Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis. Biochimica Et Biophysica Acta. 1845: 277-93. PMID 24569229 DOI: 10.1016/J.Bbcan.2014.02.001  0.384
2014 Liu P, Guo J, Gan W, Wei W. Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity. Protein & Cell. 5: 171-7. PMID 24481632 DOI: 10.1007/S13238-014-0021-8  0.441
2013 Zhong J, Shaik S, Wan L, Tron AE, Wang Z, Sun L, Inuzuka H, Wei W. SCF β-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration. Oncotarget. 4: 2339-53. PMID 24318128 DOI: 10.18632/Oncotarget.1446  0.442
2013 Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, ... ... Wei W, et al. Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nature Cell Biology. 15: 1340-50. PMID 24161930 DOI: 10.1038/Ncb2860  0.423
2013 Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, ... Wei W, et al. MC1R is a potent regulator of PTEN after UV exposure in melanocytes. Molecular Cell. 51: 409-22. PMID 23973372 DOI: 10.1016/J.Molcel.2013.08.010  0.36
2013 Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. Cell Reports. 4: 803-16. PMID 23972993 DOI: 10.1016/J.Celrep.2013.07.031  0.419
2013 Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Research. 23: 947-61. PMID 23670162 DOI: 10.1038/Cr.2013.67  0.43
2013 Zhou W, Wei W, Sun Y. Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases. Cell Research. 23: 599-619. PMID 23528706 DOI: 10.1038/Cr.2013.44  0.396
2013 Liu F, Cao J, Wu J, Sullivan K, Shen J, Ryu B, Xu Z, Wei W, Cui R. Stat3-targeted therapies overcome the acquired resistance to vemurafenib in melanomas. The Journal of Investigative Dermatology. 133: 2041-9. PMID 23344460 DOI: 10.1038/Jid.2013.32  0.365
2013 Chen H, Ma H, Inuzuka H, Diao J, Lan F, Shi YG, Wei W, Shi Y. DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase. Molecular and Cellular Biology. 33: 1139-48. PMID 23297342 DOI: 10.1128/Mcb.01191-12  0.362
2013 Wang Z, Wan L, Zhong J, Inuzuka H, Liu P, Sarkar FH, Wei W. Cdc20: a potential novel therapeutic target for cancer treatment. Current Pharmaceutical Design. 19: 3210-4. PMID 23151139 DOI: 10.2174/1381612811319180005  0.434
2012 Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KKC, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, et al. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis. Cell. 151: 913-914. PMID 30360292 DOI: 10.1016/J.Cell.2012.10.025  0.341
2012 Wang Z, Inuzuka H, Zhong J, Liu P, Sarkar FH, Sun Y, Wei W. Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2. Oncotarget. 3: 1294-300. PMID 23230084 DOI: 10.18632/Oncotarget.740  0.456
2012 Wei W, Lin HK. The key role of ubiquitination and sumoylation in signaling and cancer: a research topic. Frontiers in Oncology. 2: 187. PMID 23227454 DOI: 10.3389/Fonc.2012.00187  0.461
2012 Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, Wei W. DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget. 3: 1026-35. PMID 22976441 DOI: 10.18632/Oncotarget.640  0.406
2012 Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, ... ... Wei W, et al. Acetylation-dependent regulation of Skp2 function. Cell. 150: 179-93. PMID 22770219 DOI: 10.1016/J.Cell.2012.05.038  0.434
2012 Wang Z, Zhong J, Inuzuka H, Gao D, Shaik S, Sarkar FH, Wei W. An evolving role for DEPTOR in tumor development and progression. Neoplasia (New York, N.Y.). 14: 368-75. PMID 22745583 DOI: 10.1593/Neo.12542  0.458
2012 Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, ... ... Wei W, et al. SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. The Journal of Experimental Medicine. 209: 1289-307. PMID 22711876 DOI: 10.1084/Jem.20112446  0.394
2012 Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction. Cell Reports. 1: 434-43. PMID 22708077 DOI: 10.1016/J.Celrep.2012.04.002  0.481
2012 Wang Z, Inuzuka H, Zhong J, Wan L, Fukushima H, Sarkar FH, Wei W. Tumor suppressor functions of FBW7 in cancer development and progression. Febs Letters. 586: 1409-18. PMID 22673505 DOI: 10.1016/J.Febslet.2012.03.017  0.412
2012 Lau AW, Fukushima H, Wei W. The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis. Frontiers in Bioscience (Landmark Edition). 17: 2197-212. PMID 22652772 DOI: 10.2741/4045  0.382
2012 Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, et al. The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis. Cell. 149: 1098-111. PMID 22632973 DOI: 10.1016/J.Cell.2012.02.065  0.414
2012 Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, Shaik S, Lee DY, Finn G, Balastik M, Chen CH, Luo M, Tron AE, Decaprio JA, Zhou XZ, ... Wei W, et al. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Molecular Cell. 46: 771-83. PMID 22608923 DOI: 10.1016/J.Molcel.2012.04.012  0.472
2012 Wang Z, Zhong J, Gao D, Inuzuka H, Liu P, Wei W. DEPTOR ubiquitination and destruction by SCF(β-TrCP). American Journal of Physiology. Endocrinology and Metabolism. 303: E163-9. PMID 22454292 DOI: 10.1152/Ajpendo.00105.2012  0.347
2012 Wang Z, Fukushima H, Inuzuka H, Wan L, Liu P, Gao D, Sarkar FH, Wei W. Skp2 is a promising therapeutic target in breast cancer. Frontiers in Oncology. 1. PMID 22279619 DOI: 10.3389/Fonc.2011.00057  0.329
2012 Wang Z, Inuzuka H, Fukushima H, Wan L, Gao D, Shaik S, Sarkar FH, Wei W. Emerging roles of the FBW7 tumour suppressor in stem cell differentiation. Embo Reports. 13: 36-43. PMID 22157894 DOI: 10.1038/Embor.2011.231  0.394
2012 Wang Z, Gao D, Fukushima H, Inuzuka H, Liu P, Wan L, Sarkar FH, Wei W. Skp2: a novel potential therapeutic target for prostate cancer. Biochimica Et Biophysica Acta. 1825: 11-7. PMID 21963805 DOI: 10.1016/J.Bbcan.2011.09.002  0.327
2011 Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W. Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Molecular Cell. 44: 721-33. PMID 22152476 DOI: 10.1016/J.Molcel.2011.09.024  0.438
2011 Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, ... ... Wei W, et al. mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Molecular Cell. 44: 290-303. PMID 22017875 DOI: 10.1016/J.Molcel.2011.08.030  0.41
2011 Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W. The two faces of FBW7 in cancer drug resistance. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 851-9. PMID 22006825 DOI: 10.1002/Bies.201100101  0.334
2011 Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Mcl-1 ubiquitination and destruction. Oncotarget. 2: 239-44. PMID 21608150 DOI: 10.18632/Oncotarget.242  0.432
2011 Wei W, Kaelin WG. Good COP1 or bad COP1? In vivo veritas. The Journal of Clinical Investigation. 121: 1263-5. PMID 21403396 DOI: 10.1172/Jci57080  0.395
2011 Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, ... ... Wei W, et al. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. Nature. 471: 104-9. PMID 21368833 DOI: 10.1038/Nature09732  0.457
2010 Inuzuka H, Fukushima H, Shaik S, Wei W. Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget. 1: 685-90. PMID 21317463 DOI: 10.18632/Oncotarget.202  0.44
2010 Gao D, Wan L, Wei W. Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1. Protein & Cell. 1: 881-5. PMID 21204013 DOI: 10.1007/S13238-010-0123-X  0.426
2010 Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, ... Wei W, et al. Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Molecular Cell. 39: 797-808. PMID 20832730 DOI: 10.1016/J.Molcel.2010.08.016  0.461
2010 Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, ... ... Wei W, et al. Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. Cancer Cell. 18: 147-59. PMID 20708156 DOI: 10.1016/J.Ccr.2010.06.015  0.395
2010 Singh A, Ye M, Bucur O, Zhu S, Tanya Santos M, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R. Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. Molecular Biology of the Cell. 21: 1140-52. PMID 20110348 DOI: 10.1091/Mbc.E09-09-0795  0.404
2009 Gao D, Inuzuka H, Tseng A, Wei W. Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. Cell Division. 4: 11. PMID 19549334 DOI: 10.1186/1747-1028-4-11  0.473
2009 Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Molecular Biology of the Cell. 20: 3305-16. PMID 19477924 DOI: 10.1091/Mbc.E09-01-0092  0.501
2009 Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nature Cell Biology. 11: 397-408. PMID 19270695 DOI: 10.1038/Ncb1847  0.44
2008 Tseng A, Inuzuka H, Gao D, Singh A, Wei W. Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis. Methods in Enzymology. 446: 205-23. PMID 18603124 DOI: 10.1016/S0076-6879(08)01612-1  0.443
2007 Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG, Näär AM, Dyson NJ. Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nature Cell Biology. 9: 225-32. PMID 17187060 DOI: 10.1038/Ncb1532  0.468
2005 Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP, Farese RV, Freeman RS, Carter BD, Kaelin WG, Schlisio S. Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer. Cancer Cell. 8: 155-67. PMID 16098468 DOI: 10.1016/J.Ccr.2005.06.015  0.319
2005 Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG. The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase. Cancer Cell. 8: 25-33. PMID 16023596 DOI: 10.1016/J.Ccr.2005.06.005  0.326
2004 Yuan ZL, Guan YJ, Wang L, Wei W, Kane AB, Chin YE. Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells. Molecular and Cellular Biology. 24: 9390-400. PMID 15485908 DOI: 10.1128/Mcb.24.21.9390-9400.2004  0.416
2004 Zhang GJ, Safran M, Wei W, Sorensen E, Lassota P, Zhelev N, Neuberg DS, Shapiro G, Kaelin WG. Bioluminescent imaging of Cdk2 inhibition in vivo. Nature Medicine. 10: 643-8. PMID 15122251 DOI: 10.1038/Nm1047  0.462
2004 Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature. 428: 194-8. PMID 15014503 DOI: 10.1038/Nature02381  0.407
2004 Martin-Ruiz C, Saretzki G, Petrie J, Ladhoff J, Jeyapalan J, Wei W, Sedivy J, von Zglinicki T. Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. The Journal of Biological Chemistry. 279: 17826-33. PMID 14963037 DOI: 10.1074/Jbc.M311980200  0.602
2003 Herbig U, Wei W, Dutriaux A, Jobling WA, Sedivy JM. Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence. Aging Cell. 2: 295-304. PMID 14677632 DOI: 10.1046/J.1474-9728.2003.00067.X  0.753
2003 Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM. Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. Embo Reports. 4: 1061-6. PMID 14566323 DOI: 10.1038/Sj.Embor.7400001  0.726
2003 Hemmer R, Wei W, Dutriaux A, Sedivy J. Somatic cell knockouts of tumor suppressor genes. Methods in Molecular Biology (Clifton, N.J.). 223: 187-206. PMID 12777730 DOI: 10.1385/1-59259-329-1:187  0.579
2003 Wei W, Jobling WA, Chen W, Hahn WC, Sedivy JM. Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts. Molecular and Cellular Biology. 23: 2859-70. PMID 12665584 DOI: 10.1128/Mcb.23.8.2859-2870.2003  0.742
2003 Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM. Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts Embo Reports. 4: 1061-1065. DOI: 10.1038/sj.embor.7400001  0.653
2002 Wang Z, Bhattacharya N, Mixter PF, Wei W, Sedivy J, Magnuson NS. Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase. Biochimica Et Biophysica Acta. 1593: 45-55. PMID 12431783 DOI: 10.1016/S0167-4889(02)00347-6  0.626
2002 Han Z, Wei W, Dunaway S, Darnowski JW, Calabresi P, Sedivy J, Hendrickson EA, Balan KV, Pantazis P, Wyche JH. Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin. The Journal of Biological Chemistry. 277: 17154-60. PMID 11877436 DOI: 10.1074/Jbc.M112401200  0.634
2001 Wei W, Hemmer RM, Sedivy JM. Role of p14(ARF) in replicative and induced senescence of human fibroblasts. Molecular and Cellular Biology. 21: 6748-57. PMID 11564860 DOI: 10.1128/Mcb.21.20.6748-6757.2001  0.649
1999 Wei W, Sedivy JM. Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures. Experimental Cell Research. 253: 519-22. PMID 10585275 DOI: 10.1006/Excr.1999.4665  0.587
1998 Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proceedings of the National Academy of Sciences of the United States of America. 95: 14723-8. PMID 9843956 DOI: 10.1073/Pnas.95.25.14723  0.629
1997 Brown JP, Wei W, Sedivy JM. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science (New York, N.Y.). 277: 831-4. PMID 9242615 DOI: 10.1126/Science.277.5327.831  0.659
1997 Brown JP, Wei W, Sedivy JM. Bypass of senescenoe after disruption of p21(CIP1)/(WAF1) gene in normal diploid human fibroblasts Science. 277: 831-834. DOI: 10.1126/science.277.5327.831  0.617
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