| Year |
Citation |
Score |
| 2023 |
Tao Y, Lamas V, Du W, Zhu W, Li Y, Whittaker MN, Zuris JA, Thompson DB, Rameshbabu AP, Shu Y, Gao X, Hu JH, Pei C, Kong WJ, Liu X, ... ... Chen ZY, et al. Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo. Nature Communications. 14: 4928. PMID 37582836 DOI: 10.1038/s41467-023-40476-7 |
0.313 |
|
| 2022 |
Cui C, Wang D, Huang B, Wang F, Chen Y, Lv J, Zhang L, Han L, Liu D, Chen ZY, Li GL, Li H, Shu Y. Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss. Molecular Therapy. Nucleic Acids. 29: 400-412. PMID 36035752 DOI: 10.1016/j.omtn.2022.07.016 |
0.329 |
|
| 2021 |
Xue Y, Hu X, Wang D, Li D, Li Y, Wang F, Huang M, Gu X, Xu Z, Zhou J, Wang J, Chai R, Shen J, Chen ZY, Li GL, et al. Gene editing in a Myo6 semi-dominant mouse model rescues auditory function. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34174443 DOI: 10.1016/j.ymthe.2021.06.015 |
0.313 |
|
| 2021 |
Jang MW, Oh DY, Yi E, Liu X, Ling J, Kim N, Sharma K, Kim TY, Lee S, Kim AR, Kim MY, Kim MA, Lee M, Han JH, Han JJ, ... ... Chen ZY, et al. A nonsense variant leads to disruption of connexin-linked function and autosomal dominant auditory neuropathy spectrum disorder. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34050020 DOI: 10.1073/pnas.2019681118 |
0.315 |
|
| 2021 |
Nourbakhsh A, Colbert BM, Nisenbaum E, El-Amraoui A, Dykxhoorn DM, Koehler KR, Chen ZY, Liu XZ. Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art. Journal of the Association For Research in Otolaryngology : Jaro. PMID 33507440 DOI: 10.1007/s10162-020-00781-0 |
0.301 |
|
| 2020 |
Zhang K, Cheng X, Zhao L, Huang M, Tao Y, Zhang H, Rosenholm JM, Zhuang M, Chen ZY, Chen B, Shu Y. Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear . Molecular Therapy. Methods & Clinical Development. 18: 511-519. PMID 32953927 DOI: 10.1016/J.Omtm.2020.06.023 |
0.401 |
|
| 2020 |
Niggemann P, György B, Chen ZY. Genome and base editing for genetic hearing loss. Hearing Research. 107958. PMID 32334889 DOI: 10.1016/J.Heares.2020.107958 |
0.368 |
|
| 2019 |
Pendse ND, Lamas V, Pawlyk BS, Maeder ML, Chen ZY, Pierce EA, Liu Q. In Vivo Assessment of Potential Therapeutic Approaches for USH2A-Associated Diseases. Advances in Experimental Medicine and Biology. 1185: 91-96. PMID 31884594 DOI: 10.1007/978-3-030-27378-1_15 |
0.426 |
|
| 2019 |
Shu Y, Li W, Huang M, Quan YZ, Scheffer D, Tian C, Tao Y, Liu X, Hochedlinger K, Indzhykulian AA, Wang Z, Li H, Chen ZY. Renewed proliferation in adult mouse cochlea and regeneration of hair cells. Nature Communications. 10: 5530. PMID 31797926 DOI: 10.1038/s41467-019-13157-7 |
0.321 |
|
| 2018 |
Liu S, Wang Y, Lu Y, Li W, Liu W, Ma J, Sun F, Li M, Chen ZY, Su K, Li W. The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. Neural Plasticity. 2018: 7513258. PMID 30410537 DOI: 10.1155/2018/7513258 |
0.396 |
|
| 2017 |
Tao Y, Huang M, Shu Y, Ruprecht A, Wang H, Tang Y, Vandenberghe LH, Wang Q, Gao G, Kong WJ, Chen ZY. Delivery of Adeno-Associated Viral Vectors in Adult Mammalian Inner Ear Cell Subtypes without Auditory Dysfunction. Human Gene Therapy. PMID 29130354 DOI: 10.1089/Hum.2017.120 |
0.365 |
|
| 2016 |
Shu Y, Tao Y, Li W, Shen J, Wang Z, Chen ZY. Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo. Neural Plasticity. 2016: 9409846. PMID 28116172 DOI: 10.1155/2016/9409846 |
0.476 |
|
| 2016 |
Lee SG, Huang M, Obholzer ND, Sun S, Li W, Petrillo M, Dai P, Zhou Y, Cotanche DA, Megason SG, Li H, Chen ZY. Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration. Plos One. 11: e0157768. PMID 27351484 DOI: 10.1371/Journal.Pone.0157768 |
0.429 |
|
| 2016 |
Shu Y, Tao Y, Wang Z, Tang Y, Li H, Dai P, Gao G, Chen ZY. Identification of Adeno-associated viral vectors (AAV) that target neonatal and adult mammalian inner ear cell subtypes. Human Gene Therapy. PMID 27342665 DOI: 10.1089/hum.2016.053 |
0.362 |
|
| 2015 |
Li M, Tao Y, Shu Y, LaRochelle JR, Steinauer A, Thompson D, Schepartz A, Chen ZY, Liu DR. Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo. Journal of the American Chemical Society. PMID 26465072 DOI: 10.1021/Jacs.5B05694 |
0.331 |
|
| 2015 |
Zou B, Mittal R, Grati M, Lu Z, Shu Y, Tao Y, Feng Y, Xie D, Kong W, Yang S, Chen ZY, Liu X. The application of genome editing in studying hearing loss. Hearing Research. 327: 102-108. PMID 25987504 DOI: 10.1016/J.Heares.2015.04.016 |
0.403 |
|
| 2015 |
Scheffer DI, Shen J, Corey DP, Chen ZY. Gene Expression by Mouse Inner Ear Hair Cells during Development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6366-80. PMID 25904789 DOI: 10.1523/Jneurosci.5126-14.2015 |
0.486 |
|
| 2015 |
Scheffer DI, Zhang DS, Shen J, Indzhykulian A, Karavitaki KD, Xu YJ, Wang Q, Lin JJ, Chen ZY, Corey DP. XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia. Cell Reports. 10: 1811-8. PMID 25772365 DOI: 10.1016/J.Celrep.2015.02.042 |
0.344 |
|
| 2015 |
Li W, Wu J, Yang J, Sun S, Chai R, Chen ZY, Li H. Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway. Proceedings of the National Academy of Sciences of the United States of America. 112: 166-71. PMID 25535395 DOI: 10.1073/Pnas.1415901112 |
0.395 |
|
| 2015 |
Zuris JA, Thompson DB, Shu Y, Guilinger JP, Bessen JL, Hu JH, Maeder ML, Joung JK, Chen ZY, Liu DR. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nature Biotechnology. 33: 73-80. PMID 25357182 DOI: 10.1038/Nbt.3081 |
0.315 |
|
| 2013 |
Li W, Sun S, Chen Y, Yu H, Chen ZY, Li H. Disrupting the interaction between retinoblastoma protein and Raf-1 leads to defects in progenitor cell proliferation and survival during early inner ear development. Plos One. 8: e83726. PMID 24391814 DOI: 10.1371/Journal.Pone.0083726 |
0.401 |
|
| 2013 |
Huang M, Kantardzhieva A, Scheffer D, Liberman MC, Chen ZY. Hair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15086-94. PMID 24048839 DOI: 10.1523/JNEUROSCI.1489-13.2013 |
0.357 |
|
| 2013 |
Huang S, Han D, Wang G, Yuan Y, Song Y, Han M, Chen Z, Dai P. Sensorineural hearing loss caused by mutations in two alleles of both GJB2 and SLC26A4 genes. International Journal of Pediatric Otorhinolaryngology. 77: 379-83. PMID 23266159 DOI: 10.1016/J.Ijporl.2012.11.031 |
0.329 |
|
| 2013 |
Lu N, Chen Y, Wang Z, Chen G, Lin Q, Chen ZY, Li H. Sonic hedgehog initiates cochlear hair cell regeneration through downregulation of retinoblastoma protein. Biochemical and Biophysical Research Communications. 430: 700-5. PMID 23211596 DOI: 10.1016/J.Bbrc.2012.11.088 |
0.436 |
|
| 2011 |
Huang M, Sage C, Tang Y, Lee SG, Petrillo M, Hinds PW, Chen ZY. Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs. Cell Cycle (Georgetown, Tex.). 10: 337-51. PMID 21239885 DOI: 10.4161/Cc.10.2.14640 |
0.449 |
|
| 2010 |
Sirmaci A, Erbek S, Price J, Huang M, Duman D, Cengiz FB, Bademci G, Tokgöz-Yilmaz S, Hişmi B, Ozdağ H, Oztürk B, Kulaksizoğlu S, Yildirim E, Kokotas H, Grigoriadou M, ... ... Chen ZY, et al. A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. American Journal of Human Genetics. 86: 797-804. PMID 20451170 DOI: 10.1016/J.Ajhg.2010.04.004 |
0.404 |
|
| 2010 |
Liu X, Han D, Li J, Han B, Ouyang X, Cheng J, Li X, Jin Z, Wang Y, Bitner-Glindzicz M, Kong X, Xu H, Kantardzhieva A, Eavey RD, Seidman CE, ... ... Chen ZY, et al. Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2. American Journal of Human Genetics. 86: 65-71. PMID 20021999 DOI: 10.1016/j.ajhg.2009.11.015 |
0.326 |
|
| 2008 |
Huang M, Sage C, Li H, Xiang M, Heller S, Chen ZY. Diverse expression patterns of LIM-homeodomain transcription factors (LIM-HDs) in mammalian inner ear development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3305-12. PMID 18942141 DOI: 10.1002/Dvdy.21735 |
0.346 |
|
| 2008 |
Edge AS, Chen ZY. Hair cell regeneration. Current Opinion in Neurobiology. 18: 377-82. PMID 18929656 DOI: 10.1016/J.Conb.2008.10.001 |
0.436 |
|
| 2008 |
Williamson RE, Darrow KN, Giersch AB, Resendes BL, Huang M, Conrad GW, Chen ZY, Liberman MC, Morton CC, Tasheva ES. Expression studies of osteoglycin/mimecan (OGN) in the cochlea and auditory phenotype of Ogn-deficient mice. Hearing Research. 237: 57-65. PMID 18243607 DOI: 10.1016/J.Heares.2007.12.006 |
0.433 |
|
| 2006 |
Chen Z. Cell cycle, differentiation and regeneration: where to begin? Cell Cycle. 5: 2609-2612. PMID 17106260 DOI: 10.4161/Cc.5.22.3503 |
0.456 |
|
| 2006 |
Sage C, Huang M, Vollrath MA, Brown MC, Hinds PW, Corey DP, Vetter DE, Chen ZY. Essential role of retinoblastoma protein in mammalian hair cell development and hearing. Proceedings of the National Academy of Sciences of the United States of America. 103: 7345-50. PMID 16648263 DOI: 10.1073/Pnas.0510631103 |
0.455 |
|
| 2005 |
Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, García-Añoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science (New York, N.Y.). 307: 1114-8. PMID 15653467 DOI: 10.1126/Science.1106642 |
0.387 |
|
| 2004 |
Li H, Liu H, Sage C, Huang M, Chen ZY, Heller S. Islet-1 expression in the developing chicken inner ear. The Journal of Comparative Neurology. 477: 1-10. PMID 15281076 DOI: 10.1002/Cne.20190 |
0.407 |
|
| 2003 |
Chen Z. Applications of genomics in the inner ear. Pharmacogenomics. 4: 735-745. PMID 14596637 DOI: 10.1517/Phgs.4.6.735.22814 |
0.391 |
|
| 2003 |
Liu XZ, Ouyang XM, Xia XJ, Zheng J, Pandya A, Li F, Du LL, Welch KO, Petit C, Smith RJ, Webb BT, Yan D, Arnos KS, Corey D, Dallos P, ... ... Chen ZY, et al. Prestin, a cochlear motor protein, is defective in non-syndromic hearing loss. Human Molecular Genetics. 12: 1155-62. PMID 12719379 DOI: 10.1093/Hmg/Ddg127 |
0.306 |
|
| 2002 |
Chen ZY, Corey DP. Understanding inner ear development with gene expression profiling. Journal of Neurobiology. 53: 276-85. PMID 12382281 DOI: 10.1002/Neu.10125 |
0.446 |
|
| 2002 |
Chen ZY, Corey DP. An inner ear gene expression database. Journal of the Association For Research in Otolaryngology : Jaro. 3: 140-8. PMID 12162364 DOI: 10.1007/S101620020029 |
0.407 |
|
| 2002 |
Rehm HL, Zhang DS, Brown MC, Burgess B, Halpin C, Berger W, Morton CC, Corey DP, Chen ZY. Vascular defects and sensorineural deafness in a mouse model of Norrie disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4286-92. PMID 12040033 DOI: 10.1523/Jneurosci.22-11-04286.2002 |
0.357 |
|
| 2001 |
Chen ZY, Hasson T, Zhang DS, Schwender BJ, Derfler BH, Mooseker MS, Corey DP. Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia. Genomics. 72: 285-96. PMID 11401444 DOI: 10.1006/Geno.2000.6456 |
0.306 |
|
| 1996 |
Chen ZY, Hasson T, Kelley PM, Schwender BJ, Schwartz MF, Ramakrishnan M, Kimberling WJ, Mooseker MS, Corey DP. Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1B. Genomics. 36: 440-8. PMID 8884267 DOI: 10.1006/Geno.1996.0489 |
0.365 |
|
| 1995 |
Chen ZY, Denney RM, Breakefield XO. Norrie disease and MAO genes: nearest neighbors. Human Molecular Genetics. 4: 1729-37. PMID 8541872 DOI: 10.1093/Hmg/4.Suppl_1.1729 |
0.376 |
|
| 1995 |
Black GC, Coleman MP, Chen ZY, Nemeth AH, Davies KE, Craig IW. A bidirectional YAC walk from the Norrie disease (NDP) locus. Genomics. 25: 644-9. PMID 7759098 DOI: 10.1016/0888-7543(95)80006-8 |
0.339 |
|
| 1992 |
Hinds HL, Hendriks RW, Craig IW, Chen ZY. Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif. Genomics. 13: 896-7. PMID 1639424 DOI: 10.1016/0888-7543(92)90181-Q |
0.304 |
|
| 1991 |
Chen ZY, Hotamisligil GS, Huang JK, Wen L, Ezzeddine D, Aydin-Muderrisoglu N, Powell JF, Huang RH, Breakefield XO, Craig I. Structure of the human gene for monoamine oxidase type A. Nucleic Acids Research. 19: 4537-41. PMID 1886775 DOI: 10.1093/Nar/19.16.4537 |
0.351 |
|
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