Year |
Citation |
Score |
2023 |
Luchniak A, Kuo YW, McGuinness C, Sutradhar S, Orbach R, Mahamdeh M, Howard J. Dynamic microtubules slow down during their shrinkage phase. Biophysical Journal. PMID 36659852 DOI: 10.1016/j.bpj.2023.01.020 |
0.329 |
|
2022 |
Howard J, Chasteen A, Ouyang X, Geyer VF, Sartori P. Predicting the locations of force-generating dyneins in beating cilia and flagella. Frontiers in Cell and Developmental Biology. 10: 995847. PMID 36303602 DOI: 10.3389/fcell.2022.995847 |
0.32 |
|
2022 |
Kuo YW, Mahamdeh M, Tuna Y, Howard J. The force required to remove tubulin from the microtubule lattice by pulling on its α-tubulin C-terminal tail. Nature Communications. 13: 3651. PMID 35752623 DOI: 10.1038/s41467-022-31069-x |
0.354 |
|
2022 |
Tuna Y, Al-Hiyasat A, Howard J. Simultaneous Interference Reflection and Total Internal Reflection Fluorescence Microscopy for Imaging Dynamic Microtubules and Associated Proteins. Journal of Visualized Experiments : Jove. PMID 35604180 DOI: 10.3791/63730 |
0.31 |
|
2022 |
Kuo YW, Howard J. In Vitro Reconstitution of Microtubule Dynamics and Severing Imaged by Label-Free Interference-Reflection Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2430: 73-91. PMID 35476326 DOI: 10.1007/978-1-0716-1983-4_5 |
0.304 |
|
2021 |
Rao Q, Han L, Wang Y, Chai P, Kuo YW, Yang R, Hu F, Yang Y, Howard J, Zhang K. Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nature Structural & Molecular Biology. PMID 34556869 DOI: 10.1038/s41594-021-00656-9 |
0.343 |
|
2020 |
Orbach R, Howard J. Purification of Ciliary Tubulin from Chlamydomonas reinhardtii. Current Protocols in Protein Science. 100: e107. PMID 32568459 DOI: 10.1002/cpps.107 |
0.394 |
|
2020 |
Howard J, Hancock WO. Three Beads Are Better Than One. Biophysical Journal. 118: 1-3. PMID 31951531 DOI: 10.1016/J.Bpj.2019.12.001 |
0.532 |
|
2019 |
Kuo YW, Trottier O, Howard J. Predicted Effects of Severing Enzymes on the Length Distribution and Total Mass of Microtubules. Biophysical Journal. PMID 31708162 DOI: 10.1016/j.bpj.2019.10.027 |
0.435 |
|
2019 |
Mahamdeh M, Howard J. Implementation of Interference Reflection Microscopy for Label-free, High-speed Imaging of Microtubules. Journal of Visualized Experiments : Jove. PMID 31449260 DOI: 10.3791/59520 |
0.355 |
|
2019 |
Feofilova M, Mahamdeh M, Howard J. The Kinetics of Nucleotide Binding to Isolated Chlamydomonas Axonemes Using UV-TIRF Microscopy. Biophysical Journal. PMID 31400919 DOI: 10.1016/j.bpj.2019.07.004 |
0.44 |
|
2019 |
Luchniak A, Mahamdeh M, Howard J. Nicotinamide adenine dinucleotides and their precursor NMN have no direct effect on microtubule dynamics in purified brain tubulin. Plos One. 14: e0220794. PMID 31393939 DOI: 10.1371/journal.pone.0220794 |
0.441 |
|
2019 |
Khataee H, Howard J. Force Generated by Two Kinesin Motors Depends on the Load Direction and Intermolecular Coupling. Physical Review Letters. 122: 188101. PMID 31144901 DOI: 10.1103/PhysRevLett.122.188101 |
0.438 |
|
2019 |
Orbach R, Howard J. The dynamic and structural properties of axonemal tubulins support the high length stability of cilia. Nature Communications. 10: 1838. PMID 31015426 DOI: 10.1038/s41467-019-09779-6 |
0.384 |
|
2019 |
Kuo YW, Trottier O, Mahamdeh M, Howard J. Spastin is a dual-function enzyme that severs microtubules and promotes their regrowth to increase the number and mass of microtubules. Proceedings of the National Academy of Sciences of the United States of America. PMID 30837315 DOI: 10.1073/pnas.1818824116 |
0.468 |
|
2018 |
Mahamdeh M, Simmert S, Luchniak A, Schäffer E, Howard J. Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy. Journal of Microscopy. PMID 30044498 DOI: 10.1111/Jmi.12744 |
0.688 |
|
2018 |
Mahamdeh M, Simmert S, Łuchniak A, Schäffer E, Howard J. Label Free High Speed Wide Field Imaging of Single Microtubules using Interference Reflection Microscopy Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2758 |
0.66 |
|
2017 |
Howard J, Garzon-Coral C. Physical Limits on the Precision of Mitotic Spindle Positioning by Microtubule Pushing forces: Mechanics of mitotic spindle positioning. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28960439 DOI: 10.1002/bies.201700122 |
0.423 |
|
2017 |
Geyer VF, Sartori P, Jülicher F, Howard J. The Flagella Beat of Chlamydomonas Has Distinctly Regulated Static and Dynamic Components, which Accord with Curvature Controlled Dynein Activity Biophysical Journal. 112: 432a. DOI: 10.1016/J.BPJ.2016.11.2309 |
0.475 |
|
2016 |
Sartori P, Geyer VF, Howard J, Jülicher F. Curvature regulation of the ciliary beat through axonemal twist. Physical Review. E. 94: 042426. PMID 27841522 DOI: 10.1103/PhysRevE.94.042426 |
0.421 |
|
2016 |
Coombes C, Yamamoto A, McClellan M, Reid TA, Plooster M, Luxton GW, Alper J, Howard J, Gardner MK. Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1. Proceedings of the National Academy of Sciences of the United States of America. PMID 27803321 DOI: 10.1073/Pnas.1605397113 |
0.775 |
|
2016 |
Pécréaux J, Redemann S, Alayan Z, Mercat B, Pastezeur S, Garzon-Coral C, Hyman AA, Howard J. The Mitotic Spindle in the One-Cell C. elegans Embryo Is Positioned with High Precision and Stability. Biophysical Journal. 111: 1773-1784. PMID 27760363 DOI: 10.1016/j.bpj.2016.09.007 |
0.437 |
|
2016 |
Garzon-Coral C, Fantana HA, Howard J. A force-generating machinery maintains the spindle at the cell center during mitosis. Science (New York, N.Y.). 352: 1124-7. PMID 27230381 DOI: 10.1126/science.aad9745 |
0.408 |
|
2016 |
Sartori P, Geyer VF, Scholich A, Jülicher F, Howard J. Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella. Elife. 5. PMID 27166516 DOI: 10.7554/eLife.13258 |
0.403 |
|
2016 |
Xiao X, Geyer VF, Bowne-Anderson H, Howard J, Sbalzarini IF. Automatic optimal filament segmentation with sub-pixel accuracy using generalized linear models and B-spline level-sets. Medical Image Analysis. 32: 157-172. PMID 27104582 DOI: 10.1016/j.media.2016.03.007 |
0.313 |
|
2016 |
Borisy G, Heald R, Howard J, Janke C, Musacchio A, Nogales E. Microtubules: 50 years on from the discovery of tubulin. Nature Reviews. Molecular Cell Biology. 17: 322-8. PMID 27103327 DOI: 10.1038/Nrm.2016.45 |
0.317 |
|
2016 |
Howard J. Motor Coordination Underlying the Flagellar Beat in Chlamydomonas Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.239 |
0.448 |
|
2015 |
Bowne-Anderson H, Hibbel A, Howard J. Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment. Trends in Cell Biology. PMID 26616192 DOI: 10.1016/j.tcb.2015.08.009 |
0.407 |
|
2015 |
Hibbel A, Bogdanova A, Mahamdeh M, Jannasch A, Storch M, Schäffer E, Liakopoulos D, Howard J. Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe. Elife. 4. PMID 26576948 DOI: 10.7554/Elife.10542 |
0.718 |
|
2015 |
Hibbel A, Bogdanova A, Mahamdeh M, Jannasch A, Storch M, Schäffer E, Liakopoulos D, Howard J. Author response: Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe Elife. DOI: 10.7554/Elife.10542.016 |
0.676 |
|
2014 |
Gardner MK, Charlebois BD, Jánosi IM, Howard J, Hunt AJ, Odde DJ. Rapid Microtubule Self-Assembly Kinetics. Cell. 159: 215. PMID 28934602 DOI: 10.1016/J.Cell.2014.09.017 |
0.808 |
|
2014 |
Alper JD, Decker F, Agana B, Howard J. The motility of axonemal dynein is regulated by the tubulin code. Biophysical Journal. 107: 2872-80. PMID 25658008 DOI: 10.1016/J.Bpj.2014.10.061 |
0.783 |
|
2014 |
Liang X, Madrid J, Howard J. The microtubule-based cytoskeleton is a component of a mechanical signaling pathway in fly campaniform receptors. Biophysical Journal. 107: 2767-74. PMID 25517144 DOI: 10.1016/j.bpj.2014.10.052 |
0.334 |
|
2014 |
Podolski M, Mahamdeh M, Howard J. Stu2, the budding yeast XMAP215/Dis1 homolog, promotes assembly of yeast microtubules by increasing growth rate and decreasing catastrophe frequency. The Journal of Biological Chemistry. 289: 28087-93. PMID 25172511 DOI: 10.1074/jbc.M114.584300 |
0.41 |
|
2014 |
Mukundan V, Sartori P, Geyer VF, Jülicher F, Howard J. Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs. Biophysical Journal. 106: 2434-42. PMID 24896122 DOI: 10.1016/j.bpj.2014.03.046 |
0.461 |
|
2014 |
Garzon-Coral C, Fantana H, Howard J. Measurement of the Force that Centers the Mitotic Spindle in the Early C. elegans Embryo using Magnetic Tweezers Biophysical Journal. 106: 168a. DOI: 10.1016/J.BPJ.2013.11.954 |
0.41 |
|
2013 |
Howard J, McIntosh JR, Odde DJ. A brief scientific biography of Prof. Alan J. Hunt. Cellular and Molecular Bioengineering. 6: 356-360. PMID 24683426 DOI: 10.1007/S12195-013-0301-Z |
0.458 |
|
2013 |
Takeshita N, Mania D, Herrero S, Ishitsuka Y, Nienhaus GU, Podolski M, Howard J, Fischer R. The cell-end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans to provide polarity maintenance. Journal of Cell Science. 126: 5400-11. PMID 24101725 DOI: 10.1242/Jcs.129841 |
0.404 |
|
2013 |
Reber SB, Baumgart J, Widlund PO, Pozniakovsky A, Howard J, Hyman AA, Jülicher F. XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules. Nature Cell Biology. 15: 1116-22. PMID 23974040 DOI: 10.1038/ncb2834 |
0.492 |
|
2013 |
Trushko A, Schäffer E, Howard J. The growth speed of microtubules with XMAP215-coated beads coupled to their ends is increased by tensile force. Proceedings of the National Academy of Sciences of the United States of America. 110: 14670-5. PMID 23964126 DOI: 10.1073/Pnas.1218053110 |
0.725 |
|
2013 |
Jannasch A, Bormuth V, Storch M, Howard J, Schäffer E. Kinesin-8 is a low-force motor protein with a weakly bound slip state. Biophysical Journal. 104: 2456-64. PMID 23746518 DOI: 10.1016/J.Bpj.2013.02.040 |
0.822 |
|
2013 |
Zanic M, Widlund PO, Hyman AA, Howard J. Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels. Nature Cell Biology. 15: 688-93. PMID 23666085 DOI: 10.1038/Ncb2744 |
0.748 |
|
2013 |
Alper JD, Tovar M, Howard J. Displacement-weighted velocity analysis of gliding assays reveals that Chlamydomonas axonemal dynein preferentially moves conspecific microtubules. Biophysical Journal. 104: 1989-98. PMID 23663842 DOI: 10.1016/j.bpj.2013.03.041 |
0.789 |
|
2013 |
Liang X, Madrid J, Gärtner R, Verbavatz JM, Schiklenk C, Wilsch-Bräuninger M, Bogdanova A, Stenger F, Voigt A, Howard J. A NOMPC-dependent membrane-microtubule connector is a candidate for the gating spring in fly mechanoreceptors. Current Biology : Cb. 23: 755-63. PMID 23583554 DOI: 10.1016/j.cub.2013.03.065 |
0.356 |
|
2013 |
Bowne-Anderson H, Zanic M, Kauer M, Howard J. Microtubule dynamic instability: a new model with coupled GTP hydrolysis and multistep catastrophe. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 452-61. PMID 23532586 DOI: 10.1002/Bies.201200131 |
0.723 |
|
2013 |
Alper J, Geyer V, Mukundan V, Howard J. Reconstitution of flagellar sliding. Methods in Enzymology. 524: 343-69. PMID 23498749 DOI: 10.1016/B978-0-12-397945-2.00019-6 |
0.79 |
|
2013 |
Gardner MK, Zanic M, Howard J. Microtubule catastrophe and rescue. Current Opinion in Cell Biology. 25: 14-22. PMID 23092753 DOI: 10.1016/J.Ceb.2012.09.006 |
0.769 |
|
2013 |
Zanic M, Widlund P, Hyman A, Howard J. XMAP215 and EB1 act in Synergy to Promote Microtubule Growth Biophysical Journal. 104: 550a. DOI: 10.1016/J.Bpj.2012.11.3051 |
0.767 |
|
2012 |
Segal M, Soifer I, Petzold H, Howard J, Elbaum M, Reiner O. Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon. Biology Open. 1: 220-31. PMID 23213412 DOI: 10.1242/Bio.2012307 |
0.426 |
|
2012 |
Widlund PO, Podolski M, Reber S, Alper J, Storch M, Hyman AA, Howard J, Drechsel DN. One-step purification of assembly-competent tubulin from diverse eukaryotic sources. Molecular Biology of the Cell. 23: 4393-401. PMID 22993214 DOI: 10.1091/Mbc.E12-06-0444 |
0.775 |
|
2012 |
Bormuth V, Nitzsche B, Ruhnow F, Mitra A, Storch M, Rammner B, Howard J, Diez S. The highly processive kinesin-8, Kip3, switches microtubule protofilaments with a bias toward the left. Biophysical Journal. 103: L4-6. PMID 22828351 DOI: 10.1016/J.Bpj.2012.05.024 |
0.823 |
|
2012 |
Friel CT, Howard J. Coupling of kinesin ATP turnover to translocation and microtubule regulation: one engine, many machines. Journal of Muscle Research and Cell Motility. 33: 377-83. PMID 22447431 DOI: 10.1007/s10974-012-9289-6 |
0.47 |
|
2012 |
Leduc C, Padberg-Gehle K, Varga V, Helbing D, Diez S, Howard J. Molecular crowding creates traffic jams of kinesin motors on microtubules. Proceedings of the National Academy of Sciences of the United States of America. 109: 6100-5. PMID 22431622 DOI: 10.1073/pnas.1107281109 |
0.471 |
|
2012 |
Tropini C, Roth EA, Zanic M, Gardner MK, Howard J. Islands containing slowly hydrolyzable GTP analogs promote microtubule rescues. Plos One. 7: e30103. PMID 22272281 DOI: 10.1371/Journal.Pone.0030103 |
0.739 |
|
2012 |
Wadsworth P, Howard J. Microtubules and motors Molecular Biology of the Cell. 23: 973-973. DOI: 10.1091/Mbc.E11-12-0975 |
0.532 |
|
2012 |
Podolski M, Howard J. Stu2p, the Budding Yeast Homologue of XMAP215, is a Weak Microtubule Polymerase that Promotes Rescues Biophysical Journal. 102: 700a. DOI: 10.1016/j.bpj.2011.11.3800 |
0.449 |
|
2012 |
Jannasch A, Storch M, Howard J, Schäffer E. Kinesin-8 is a Weak Motor Protein with a Weakly Bound Slip State Biophysical Journal. 102: 38a. DOI: 10.1016/J.Bpj.2011.11.234 |
0.738 |
|
2012 |
Geyer VF, Satori P, Jülicher F, Howard J. Characterization of the Beat of Chlamydomonas Axonemes Biophysical Journal. 102: 372a. DOI: 10.1016/j.bpj.2011.11.2031 |
0.353 |
|
2012 |
Alper J, Tovar M, Podolski M, Widlund P, Hyman T, Drechsel D, Howard J. In Vitro Gliding Assays Indicate that Chlamydomonas Dynein Moves Microtubules Polymerized from Chlamydomonas Axonemal Tubulin Faster than those Polymerized from Porcine Brain Tubulin Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2030 |
0.794 |
|
2012 |
Fantana HA, Howard J. Measuring the Mechanical Properties of the Mechanism Centering the Mitotic Spindle in C. Elegans Biophysical Journal. 102: 346a. DOI: 10.1016/j.bpj.2011.11.1896 |
0.407 |
|
2012 |
Howard J, Fantana H, Pecreaux J, Garzon-Coral C, Redemann S, Hyman AA. The Forces that Center the Mitotic Spindle Biophysical Journal. 102: 223a. DOI: 10.1016/j.bpj.2011.11.1222 |
0.453 |
|
2011 |
Gardner MK, Zanic M, Gell C, Bormuth V, Howard J. Depolymerizing kinesins Kip3 and MCAK shape cellular microtubule architecture by differential control of catastrophe. Cell. 147: 1092-103. PMID 22118464 DOI: 10.1016/J.Cell.2011.10.037 |
0.812 |
|
2011 |
Mayr MI, Storch M, Howard J, Mayer TU. A non-motor microtubule binding site is essential for the high processivity and mitotic function of kinesin-8 Kif18A. Plos One. 6: e27471. PMID 22102900 DOI: 10.1371/Journal.Pone.0027471 |
0.486 |
|
2011 |
Alper J, Howard J. Hybrid four-headed myosin motor engineered with antagonistic motor domains. Proceedings of the National Academy of Sciences of the United States of America. 108: 15663-4. PMID 21900606 DOI: 10.1073/Pnas.1112017108 |
0.772 |
|
2011 |
Friel CT, Howard J. The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization. The Embo Journal. 30: 3928-39. PMID 21873978 DOI: 10.1038/emboj.2011.290 |
0.483 |
|
2011 |
Gardner MK, Charlebois BD, Jánosi IM, Howard J, Hunt AJ, Odde DJ. Rapid microtubule self-assembly kinetics. Cell. 146: 582-92. PMID 21854983 DOI: 10.1016/j.cell.2011.06.053 |
0.812 |
|
2011 |
Bormuth V, Zörgibel F, Schäffer E, Howard J. Functional surface attachment in a sandwich geometry of GFP-labeled motor proteins. Methods in Molecular Biology (Clifton, N.J.). 778: 11-8. PMID 21809197 DOI: 10.1007/978-1-61779-261-8_2 |
0.807 |
|
2011 |
Friel CT, Bagshaw CR, Howard J. Analysing the ATP turnover cycle of microtubule motors. Methods in Molecular Biology (Clifton, N.J.). 777: 177-92. PMID 21773929 DOI: 10.1007/978-1-61779-252-6_13 |
0.439 |
|
2011 |
Gell C, Friel CT, Borgonovo B, Drechsel DN, Hyman AA, Howard J. Purification of tubulin from porcine brain. Methods in Molecular Biology (Clifton, N.J.). 777: 15-28. PMID 21773918 DOI: 10.1007/978-1-61779-252-6_2 |
0.411 |
|
2011 |
Howard J, Grill SW, Bois JS. Turing's next steps: the mechanochemical basis of morphogenesis. Nature Reviews. Molecular Cell Biology. 12: 392-8. PMID 21602907 DOI: 10.1038/Nrm3120 |
0.367 |
|
2011 |
Widlund PO, Stear JH, Pozniakovsky A, Zanic M, Reber S, Brouhard GJ, Hyman AA, Howard J. XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. Proceedings of the National Academy of Sciences of the United States of America. 108: 2741-6. PMID 21282620 DOI: 10.1073/Pnas.1016498108 |
0.781 |
|
2011 |
Liang X, Madrid J, Saleh HS, Howard J. NOMPC, a member of the TRP channel family, localizes to the tubular body and distal cilium of Drosophila campaniform and chordotonal receptor cells. Cytoskeleton (Hoboken, N.J.). 68: 1-7. PMID 21069788 DOI: 10.1002/cm.20493 |
0.302 |
|
2011 |
Gardner MK, Charlebois BD, Jánosi IM, Howard J, Hunt AJ, Odde DJ. Kinetics of Microtubule Assembly Biophysical Journal. 100: 530a-531a. DOI: 10.1016/J.Bpj.2010.12.3098 |
0.791 |
|
2011 |
Liang X, Madrid J, Saleh H, Howard J. Molecular Organization of the Distal Cilium, a Potential Mechanotransduction Site, in Campaniform Receptor of Drosophila Melanogaster Biophysical Journal. 100: 281a. DOI: 10.1016/j.bpj.2010.12.1742 |
0.312 |
|
2010 |
Bechstedt S, Albert JT, Kreil DP, Müller-Reichert T, Göpfert MC, Howard J. A doublecortin containing microtubule-associated protein is implicated in mechanotransduction in Drosophila sensory cilia. Nature Communications. 1: 11. PMID 20975667 DOI: 10.1038/ncomms1007 |
0.36 |
|
2010 |
Redemann S, Pecreaux J, Goehring NW, Khairy K, Stelzer EH, Hyman AA, Howard J. Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos. Plos One. 5: e12301. PMID 20808841 DOI: 10.1371/Journal.Pone.0012301 |
0.36 |
|
2010 |
Nitzsche B, Bormuth V, Bräuer C, Howard J, Ionov L, Kerssemakers J, Korten T, Leduc C, Ruhnow F, Diez S. Studying kinesin motors by optical 3D-nanometry in gliding motility assays. Methods in Cell Biology. 95: 247-71. PMID 20466139 DOI: 10.1016/S0091-679X(10)95014-0 |
0.825 |
|
2010 |
Gell C, Bormuth V, Brouhard GJ, Cohen DN, Diez S, Friel CT, Helenius J, Nitzsche B, Petzold H, Ribbe J, Schäffer E, Stear JH, Trushko A, Varga V, Widlund PO, ... ... Howard J, et al. Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy. Methods in Cell Biology. 95: 221-45. PMID 20466138 DOI: 10.1016/S0091-679X(10)95013-9 |
0.791 |
|
2010 |
Sanhaji M, Friel CT, Kreis NN, Krämer A, Martin C, Howard J, Strebhardt K, Yuan J. Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1. Molecular and Cellular Biology. 30: 2594-607. PMID 20368358 DOI: 10.1128/MCB.00098-10 |
0.34 |
|
2010 |
Friedrich BM, Riedel-Kruse IH, Howard J, Jülicher F. High-precision tracking of sperm swimming fine structure provides strong test of resistive force theory. The Journal of Experimental Biology. 213: 1226-34. PMID 20348333 DOI: 10.1242/Jeb.039800 |
0.323 |
|
2010 |
Bormuth V, Varga V, Howard J, Schäffer E. Breaking of bonds between a kinesin motor and microtubules causes protein friction Proceedings of Spie - the International Society For Optical Engineering. 7762. DOI: 10.1117/12.863545 |
0.801 |
|
2010 |
Friel CT, Howard J. MCAK (Kinesin-13) has an Unconventional ATP Hydrolysis Cycle Adapted for Microtubule Depolymerization Biophysical Journal. 98: 166a. DOI: 10.1016/J.BPJ.2009.12.898 |
0.429 |
|
2009 |
Zanic M, Stear JH, Hyman AA, Howard J. EB1 recognizes the nucleotide state of tubulin in the microtubule lattice. Plos One. 4: e7585. PMID 19851462 DOI: 10.1371/Journal.Pone.0007585 |
0.78 |
|
2009 |
Varga V, Leduc C, Bormuth V, Diez S, Howard J. Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization. Cell. 138: 1174-83. PMID 19766569 DOI: 10.1016/J.Cell.2009.07.032 |
0.833 |
|
2009 |
Bormuth V, Varga V, Howard J, Schäffer E. Protein friction limits diffusive and directed movements of kinesin motors on microtubules. Science (New York, N.Y.). 325: 870-3. PMID 19679813 DOI: 10.1126/Science.1174923 |
0.822 |
|
2009 |
Howard J, Hyman AA. Growth, fluctuation and switching at microtubule plus ends. Nature Reviews. Molecular Cell Biology. 10: 569-74. PMID 19513082 DOI: 10.1038/nrm2713 |
0.456 |
|
2009 |
Howard J. Mechanical signaling in networks of motor and cytoskeletal proteins. Annual Review of Biophysics. 38: 217-34. PMID 19416067 DOI: 10.1146/annurev.biophys.050708.133732 |
0.428 |
|
2009 |
Pecreaux J, Redemann S, Hyman AA, Howard J. Role of cortical rigidity in spindle positioning in C. elegans Biophysical Journal. 96: 509a. DOI: 10.1016/j.bpj.2008.12.2623 |
0.393 |
|
2009 |
Bormuth V, Varga V, Howard J, Schäffer E. Measurement Of The Protein Friction Between The Yeast Kinesin-8 Kip3p And Microtubules Biophysical Journal. 96: 508a-509a. DOI: 10.1016/J.Bpj.2008.12.2622 |
0.812 |
|
2008 |
Crevenna AH, Madathil S, Cohen DN, Wagenbach M, Fahmy K, Howard J. Secondary structure and compliance of a predicted flexible domain in kinesin-1 necessary for cooperation of motors. Biophysical Journal. 95: 5216-27. PMID 18775962 DOI: 10.1529/biophysj.108.132449 |
0.441 |
|
2008 |
Bormuth V, Jannasch A, Ander M, van Kats CM, van Blaaderen A, Howard J, Schäffer E. Optical trapping of coated microspheres. Optics Express. 16: 13831-44. PMID 18772994 DOI: 10.1016/J.Bpj.2008.12.3409 |
0.774 |
|
2008 |
Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA. XMAP215 is a processive microtubule polymerase. Cell. 132: 79-88. PMID 18191222 DOI: 10.1016/J.Cell.2007.11.043 |
0.768 |
|
2008 |
Howard J. Molecular Mechanics of Cells and Tissues Cellular and Molecular Bioengineering. 1: 24-32. DOI: 10.1007/S12195-008-0004-Z |
0.437 |
|
2007 |
Bechstedt S, Howard J. Models of hair cell mechanotransduction. Current Topics in Membranes. 59: 399-424. PMID 25168144 DOI: 10.1016/S1063-5823(06)59015-5 |
0.359 |
|
2007 |
Howard J, Toli?-Nørrelykke IM. Bundling, sliding, and pulling microtubules in cells and in silico. Hfsp Journal. 1: 11-4. PMID 19404456 DOI: 10.2976/1.2740563/10.2976/1 |
0.468 |
|
2007 |
Riedel-Kruse IH, Hilfinger A, Howard J, Jülicher F. How molecular motors shape the flagellar beat. Hfsp Journal. 1: 192-208. PMID 19404446 DOI: 10.2976/1.2773861 |
0.439 |
|
2007 |
Elie-Caille C, Severin F, Helenius J, Howard J, Muller DJ, Hyman AA. Straight GDP-tubulin protofilaments form in the presence of taxol. Current Biology : Cb. 17: 1765-70. PMID 17919908 DOI: 10.1016/j.cub.2007.08.063 |
0.472 |
|
2007 |
Dinu CZ, Chrisey DB, Diez S, Howard J. Cellular motors for molecular manufacturing. Anatomical Record (Hoboken, N.J. : 2007). 290: 1203-12. PMID 17847054 DOI: 10.1002/ar.20599 |
0.448 |
|
2007 |
Leduc C, Ruhnow F, Howard J, Diez S. Detection of fractional steps in cargo movement by the collective operation of kinesin-1 motors. Proceedings of the National Academy of Sciences of the United States of America. 104: 10847-52. PMID 17569782 DOI: 10.1073/pnas.0701864104 |
0.443 |
|
2007 |
Bormuth V, Howard J, Schäffer E. LED illumination for video-enhanced DIC imaging of single microtubules. Journal of Microscopy. 226: 1-5. PMID 17381703 DOI: 10.1111/J.1365-2818.2007.01756.X |
0.767 |
|
2007 |
Schäffer E, Nørrelykke SF, Howard J. Surface forces and drag coefficients of microspheres near a plane surface measured with optical tweezers. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3654-65. PMID 17326669 DOI: 10.1021/La0622368 |
0.635 |
|
2007 |
Howard J, Hyman AA. Microtubule polymerases and depolymerases. Current Opinion in Cell Biology. 19: 31-5. PMID 17184986 DOI: 10.1016/j.ceb.2006.12.009 |
0.475 |
|
2006 |
Dinu CZ, Opitz J, Pompe W, Howard J, Mertig M, Diez S. Parallel manipulation of bifunctional DNA molecules on structured surfaces using kinesin-driven microtubules. Small (Weinheim An Der Bergstrasse, Germany). 2: 1090-8. PMID 17193173 DOI: 10.1002/smll.200600112 |
0.347 |
|
2006 |
Pecreaux J, Röper JC, Kruse K, Jülicher F, Hyman AA, Grill SW, Howard J. Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators. Current Biology : Cb. 16: 2111-22. PMID 17084695 DOI: 10.1016/j.cub.2006.09.030 |
0.474 |
|
2006 |
Kerssemakers J, Howard J, Hess H, Diez S. The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy. Proceedings of the National Academy of Sciences of the United States of America. 103: 15812-7. PMID 17035506 DOI: 10.1073/Pnas.0510400103 |
0.477 |
|
2006 |
Varga V, Helenius J, Tanaka K, Hyman AA, Tanaka TU, Howard J. Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner. Nature Cell Biology. 8: 957-62. PMID 16906145 DOI: 10.1038/ncb1462 |
0.548 |
|
2006 |
Helenius J, Brouhard G, Kalaidzidis Y, Diez S, Howard J. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. Nature. 441: 115-9. PMID 16672973 DOI: 10.1038/Nature04736 |
0.764 |
|
2006 |
Howard J. Elastic and damping forces generated by confined arrays of dynamic microtubules. Physical Biology. 3: 54-66. PMID 16582470 DOI: 10.1088/1478-3975/3/1/006 |
0.456 |
|
2006 |
Tolić-Nørrelykke SF, Schäffer E, Howard J, Pavone FS, Jülicher F, Flyvbjerg H. Calibration of optical tweezers with positional detection in the back focal plane Review of Scientific Instruments. 77. DOI: 10.1063/1.2356852 |
0.627 |
|
2006 |
Dinu CZ, Opitz J, Pompe W, Howard J, Mertig M, Diez S. Cover Picture: Parallel Manipulation of Bifunctional DNA Molecules on Structured Surfaces Using Kinesin-Driven Microtubules (Small 8-9/2006) Small. 2: 927-927. DOI: 10.1002/Smll.200690032 |
0.342 |
|
2005 |
Riedel IH, Kruse K, Howard J. A self-organized vortex array of hydrodynamically entrained sperm cells. Science (New York, N.Y.). 309: 300-3. PMID 16002619 DOI: 10.1126/science.1110329 |
0.316 |
|
2005 |
Poole K, Khairy K, Friedrichs J, Franz C, Cisneros DA, Howard J, Mueller D. Molecular-scale topographic cues induce the orientation and directional movement of fibroblasts on two-dimensional collagen surfaces. Journal of Molecular Biology. 349: 380-6. PMID 15890202 DOI: 10.1016/J.Jmb.2005.03.064 |
0.323 |
|
2004 |
Jiang F, Khairy K, Poole K, Howard J, Müller DJ. Creating nanoscopic collagen matrices using atomic force microscopy. Microscopy Research and Technique. 64: 435-40. PMID 15549696 DOI: 10.1002/Jemt.20101 |
0.372 |
|
2004 |
Jiang F, Hörber H, Howard J, Müller DJ. Assembly of collagen into microribbons: effects of pH and electrolytes. Journal of Structural Biology. 148: 268-78. PMID 15522775 DOI: 10.1016/j.jsb.2004.07.001 |
0.343 |
|
2004 |
Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/Jcb.200408113 |
0.488 |
|
2004 |
Haeberle H, Fujiwara M, Chuang J, Medina MM, Panditrao MV, Bechstedt S, Howard J, Lumpkin EA. Molecular profiling reveals synaptic release machinery in Merkel cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 14503-8. PMID 15448211 DOI: 10.1073/pnas.0406308101 |
0.759 |
|
2004 |
Sawhney RK, Howard J. Molecular dissection of the fibroblast-traction machinery. Cell Motility and the Cytoskeleton. 58: 175-85. PMID 15146536 DOI: 10.1002/Cm.20004 |
0.789 |
|
2004 |
Schief WR, Clark RH, Crevenna AH, Howard J. Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism. Proceedings of the National Academy of Sciences of the United States of America. 101: 1183-8. PMID 14734813 DOI: 10.1073/pnas.0304369101 |
0.377 |
|
2003 |
Grill SW, Howard J, Schäffer E, Stelzer EH, Hyman AA. The distribution of active force generators controls mitotic spindle position. Science (New York, N.Y.). 301: 518-21. PMID 12881570 DOI: 10.1126/Science.1086560 |
0.687 |
|
2003 |
Hunter AW, Caplow M, Coy DL, Hancock WO, Diez S, Wordeman L, Howard J. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Molecular Cell. 11: 445-57. PMID 12620232 DOI: 10.1016/S1097-2765(03)00049-2 |
0.694 |
|
2003 |
Diez S, Reuther C, Dinu C, Seidel R, Mertig M, Pompe W, Howard J. Stretching and Transporting DNA Molecules Using Motor Proteins Nano Letters. 3: 1251-1254. DOI: 10.1021/Nl034504H |
0.43 |
|
2003 |
Clemmens J, Hess H, Howard J, Vogel V. Analysis of Microtubule Guidance in Open Microfabricated Channels Coated with the Motor Protein Kinesin† Langmuir. 19: 1738-1744. DOI: 10.1021/La026155X |
0.445 |
|
2002 |
Sawhney RK, Howard J. Slow local movements of collagen fibers by fibroblasts drive the rapid global self-organization of collagen gels. The Journal of Cell Biology. 157: 1083-91. PMID 12058022 DOI: 10.1083/Jcb.200203069 |
0.776 |
|
2002 |
Vinh DB, Kern JW, Hancock WO, Howard J, Davis TN. Reconstitution and characterization of budding yeast gamma-tubulin complex. Molecular Biology of the Cell. 13: 1144-57. PMID 11950928 DOI: 10.1091/Mbc.02-01-0607 |
0.618 |
|
2002 |
Diez S, Schief WR, Howard J. Molecular motors: single-molecule recordings made easy. Current Biology : Cb. 12: R203-5. PMID 11909546 DOI: 10.1016/S0960-9822(02)00750-9 |
0.442 |
|
2002 |
Hess H, Howard J, Vogel V. A Piconewton Forcemeter Assembled from Microtubules and Kinesins Nano Letters. 2: 1113-1115. DOI: 10.1021/Nl025724I |
0.459 |
|
2001 |
Schief WR, Howard J. Conformational changes during kinesin motility. Current Opinion in Cell Biology. 13: 19-28. PMID 11163129 DOI: 10.1016/S0955-0674(00)00169-1 |
0.405 |
|
2001 |
Hess H, Clemmens J, Qin D, Howard J, Vogel V. Light-Controlled Molecular Shuttles Made from Motor Proteins Carrying Cargo on Engineered Surfaces Nano Letters. 1: 235-239. DOI: 10.1021/Nl015521E |
0.433 |
|
1999 |
Coy DL, Hancock WO, Wagenbach M, Howard J. Kinesin's tail domain is an inhibitory regulator of the motor domain. Nature Cell Biology. 1: 288-92. PMID 10559941 DOI: 10.1038/13001 |
0.638 |
|
1999 |
Hancock WO, Howard J. Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains. Proceedings of the National Academy of Sciences of the United States of America. 96: 13147-52. PMID 10557288 DOI: 10.1073/Pnas.96.23.13147 |
0.646 |
|
1999 |
Coy DL, Wagenbach M, Howard J. Kinesin takes one 8-nm step for each ATP that it hydrolyzes. Journal of Biological Chemistry. 274: 3667-3671. PMID 9920916 DOI: 10.1074/Jbc.274.6.3667 |
0.413 |
|
1999 |
Dennis JR, Howard J, Vogel V. Molecular shuttles: Directed motion of microtubules along nanoscale kinesin tracks Nanotechnology. 10: 232-236. DOI: 10.1088/0957-4484/10/3/302 |
0.424 |
|
1998 |
Hancock WO, Howard J. Processivity of the motor protein kinesin requires two heads. The Journal of Cell Biology. 140: 1395-405. PMID 9508772 DOI: 10.1083/Jcb.140.6.1395 |
0.672 |
|
1996 |
Howard J. The movement of kinesin along microtubules Annual Review of Physiology. 58: 703-729. PMID 8815816 DOI: 10.1146/Annurev.Ph.58.030196.003415 |
0.502 |
|
1996 |
Gittes F, Meyhöfer E, Baek S, Howard J. Directional loading of the kinesin motor molecule as it buckles a microtubule. Biophysical Journal. 70: 418-29. PMID 8770218 DOI: 10.1016/S0006-3495(96)79585-1 |
0.789 |
|
1995 |
Meyhöfer E, Howard J. The force generated by a single kinesin molecule against an elastic load. Proceedings of the National Academy of Sciences of the United States of America. 92: 574-8. PMID 7831332 DOI: 10.1073/Pnas.92.2.574 |
0.465 |
|
1995 |
Mickey B, Howard J. Rigidity of microtubules is increased by stabilizing agents Journal of Cell Biology. 130: 909-917. PMID 7642706 DOI: 10.1083/Jcb.130.4.909 |
0.462 |
|
1995 |
Ray S, Wolf SG, Howard J, Downing KH. Kinesin does not support the motility of zinc-macrotubes. Cell Motility and the Cytoskeleton. 30: 146-52. PMID 7606807 DOI: 10.1002/Cm.970300206 |
0.419 |
|
1994 |
Howard J, Hyman AA. Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. Methods in Cell Biology. 39: 105-13. PMID 8246791 DOI: 10.1016/S0091-679X(08)60164-8 |
0.512 |
|
1994 |
Howard J. Clamping down on myosin Nature. 368: 98-99. PMID 8139673 DOI: 10.1038/368098A0 |
0.348 |
|
1994 |
Corey DP, Howard J. Models for ion channel gating with compliant states. Biophysical Journal. 66: 1254-7. PMID 8038396 DOI: 10.1016/S0006-3495(94)80909-9 |
0.501 |
|
1994 |
Hunt AJ, Gittes F, Howard J. The force exerted by a single kinesin molecule against a viscous load. Biophysical Journal. 67: 766-81. PMID 7948690 DOI: 10.1016/S0006-3495(94)80537-5 |
0.827 |
|
1994 |
Coy DL, Howard J. Organelle transport and sorting in axons Current Opinion in Neurobiology. 4: 662-667. PMID 7849522 DOI: 10.1016/0959-4388(94)90007-8 |
0.386 |
|
1993 |
Gittes F, Mickey B, Nettleton J, Howard J. Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape. The Journal of Cell Biology. 120: 923-34. PMID 8432732 DOI: 10.1083/Jcb.120.4.923 |
0.793 |
|
1993 |
Howard J. One giant step for kinesin Nature. 365: 696-697. PMID 8413646 DOI: 10.1038/365696B0 |
0.337 |
|
1993 |
Howard J. Wrestling with kinesin Nature. 364: 390-391. PMID 8332208 DOI: 10.1038/364390A0 |
0.468 |
|
1993 |
Hunt AJ, Howard J. Kinesin swivels to permit microtubule movement in any direction. Proceedings of the National Academy of Sciences of the United States of America. 90: 11653-7. PMID 8265603 DOI: 10.1073/Pnas.90.24.11653 |
0.75 |
|
1993 |
Howard J, Hunt AJ, Baek S. Assay of microtubule movement driven by single kinesin molecules. Methods in Cell Biology. 39: 137-47. PMID 8246794 DOI: 10.1016/S0091-679X(08)60167-3 |
0.729 |
|
1993 |
Ray S, Meyhöfer E, Milligan RA, Howard J. Kinesin follows the microtubule's protofilament axis. The Journal of Cell Biology. 121: 1083-93. PMID 8099076 DOI: 10.1083/Jcb.121.5.1083 |
0.459 |
|
1989 |
Howard J, Hudspeth AJ, Vale RD. Movement of microtubules by single kinesin molecules. Nature. 342: 154-8. PMID 2530455 DOI: 10.1038/342154A0 |
0.75 |
|
1988 |
Howard J, Hudspeth AJ. Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell. Neuron. 1: 189-99. PMID 2483095 DOI: 10.1016/0896-6273(88)90139-0 |
0.637 |
|
1988 |
Roberts WM, Howard J, Hudspeth AJ. Hair cells: transduction, tuning, and transmission in the inner ear. Annual Review of Cell Biology. 4: 63-92. PMID 2461723 DOI: 10.1146/annurev.cb.04.110188.000431 |
0.709 |
|
1987 |
Howard J, Hudspeth AJ. Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell. Proceedings of the National Academy of Sciences of the United States of America. 84: 3064-8. PMID 3495007 DOI: 10.1073/Pnas.84.9.3064 |
0.662 |
|
1987 |
Laughlin SB, Howard J, Blakeslee B. Synaptic limitations to contrast coding in the retina of the blowfly Calliphora. Proceedings of the Royal Society of London. Series B, Biological Sciences. 231: 437-67. PMID 2892202 DOI: 10.1098/Rspb.1987.0054 |
0.492 |
|
1987 |
Howard J, Blakeslee B, Laughlin SB. The intracellular pupil mechanism and photoreceptor signal: noise ratios in the fly Lucilia cuprina. Proceedings of the Royal Society of London. Series B, Biological Sciences. 231: 415-35. PMID 2892201 DOI: 10.1098/Rspb.1987.0053 |
0.504 |
|
1986 |
Howard J, Ashmore JF. Stiffness of sensory hair bundles in the sacculus of the frog. Hearing Research. 23: 93-104. PMID 3488306 DOI: 10.1016/0378-5955(86)90178-4 |
0.611 |
|
1984 |
Blest AD, Couet HGD, Howard J, Wilcox M, Sigmund C. The extrarhabdomeral cytoskeleton in photoreceptors of Diptera. I. Labile components in the cytoplasm Proceedings of the Royal Society B: Biological Sciences. 220: 339-352. DOI: 10.1098/Rspb.1984.0004 |
0.386 |
|
1983 |
Howard J, Snyder AW. Transduction as a limitation on compound eye function and design Proceedings of the Royal Society B: Biological Sciences. 217: 287-307. DOI: 10.1098/Rspb.1983.0011 |
0.487 |
|
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