John Gerhart - Publications

Molecular & Cell Biology University of California, Berkeley, Berkeley, CA 
Developmental Biology, Genetics

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fritzenwanker JH, Uhlinger KR, Gerhart J, Silva E, Lowe CJ. Untangling posterior growth and segmentation by analyzing mechanisms of axis elongation in hemichordates. Proceedings of the National Academy of Sciences of the United States of America. PMID 30967509 DOI: 10.1073/pnas.1817496116  0.52
2018 Darras S, Fritzenwanker JH, Uhlinger KR, Farrelly E, Pani AM, Hurley IA, Norris RP, Osovitz M, Terasaki M, Wu M, Aronowicz J, Kirschner M, Gerhart JC, Lowe CJ. Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development. Plos Biology. 16: e2003698. PMID 29337984 DOI: 10.1371/journal.pbio.2003698  0.52
2015 Lowe CJ, Terasaki M, Wu M, Freeman RM, Runft L, Kwan K, Haigo S, Aronowicz J, Lander E, Gruber C, Smith M, Kirschner M, Gerhart J. Correction: Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution. Plos Biology. 13: e1002354. PMID 26714185 DOI: 10.1371/journal.pbio.1002354  0.52
2015 Simakov O, Kawashima T, Marlétaz F, Jenkins J, Koyanagi R, Mitros T, Hisata K, Bredeson J, Shoguchi E, Gyoja F, Yue JX, Chen YC, Freeman RM, Sasaki A, Hikosaka-Katayama T, ... ... Gerhart J, et al. Hemichordate genomes and deuterostome origins. Nature. PMID 26580012 DOI: 10.1038/nature16150  1
2015 Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, Klein AM, Horb M, Gygi SP, Kirschner MW. On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development. Developmental Cell. 35: 383-94. PMID 26555057 DOI: 10.1016/j.devcel.2015.10.010  1
2015 Lowe CJ, Clarke DN, Medeiros DM, Rokhsar DS, Gerhart J. The deuterostome context of chordate origins. Nature. 520: 456-65. PMID 25903627 DOI: 10.1038/nature14434  1
2014 Satoh N, Tagawa K, Lowe CJ, Yu JK, Kawashima T, Takahashi H, Ogasawara M, Kirschner M, Hisata K, Su YH, Gerhart J. On a possible evolutionary link of the stomochord of hemichordates to pharyngeal organs of chordates. Genesis (New York, N.Y. : 2000). 52: 925-34. PMID 25303744 DOI: 10.1002/dvg.22831  1
2014 Fritzenwanker JH, Gerhart J, Freeman RM, Lowe CJ. The Fox/Forkhead transcription factor family of the hemichordate Saccoglossus kowalevskii. Evodevo. 5: 17. PMID 24987514 DOI: 10.1186/2041-9139-5-17  1
2014 Gerhart J. From feedback inhibition to allostery: the enduring example of aspartate transcarbamoylase. The Febs Journal. 281: 612-20. PMID 23953008 DOI: 10.1111/febs.12483  1
2012 Gerhart JC, Martin GR, Wieschaus EF. Introducing WIREs Developmental Biology. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 1-2. PMID 23801663 DOI: 10.1002/wdev.13  1
2012 Freeman R, Ikuta T, Wu M, Koyanagi R, Kawashima T, Tagawa K, Humphreys T, Fang GC, Fujiyama A, Saiga H, Lowe C, Worley K, Jenkins J, Schmutz J, Kirschner M, ... ... Gerhart J, et al. Identical genomic organization of two hemichordate hox clusters. Current Biology : Cb. 22: 2053-8. PMID 23063438 DOI: 10.1016/j.cub.2012.08.052  1
2011 Darras S, Gerhart J, Terasaki M, Kirschner M, Lowe CJ. β-catenin specifies the endomesoderm and defines the posterior organizer of the hemichordate Saccoglossus kowalevskii. Development (Cambridge, England). 138: 959-70. PMID 21303849 DOI: 10.1242/dev.059493  1
2010 Gerhart J. Enzymes, embryos, and ancestors. Annual Review of Cell and Developmental Biology. 26: 1-20. PMID 20929311 DOI: 10.1146/annurev-cellbio-100109-104101  1
2010 Lemons D, Fritzenwanker JH, Gerhart J, Lowe CJ, McGinnis W. Co-option of an anteroposterior head axis patterning system for proximodistal patterning of appendages in early bilaterian evolution. Developmental Biology. 344: 358-62. PMID 20435033 DOI: 10.1016/j.ydbio.2010.04.022  1
2008 Freeman RM, Wu M, Cordonnier-Pratt MM, Pratt LH, Gruber CE, Smith M, Lander ES, Stange-Thomann N, Lowe CJ, Gerhart J, Kirschner M. cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism. The Biological Bulletin. 214: 284-302. PMID 18574105  1
2007 Gerhart J, Kirschner M. The theory of facilitated variation. Proceedings of the National Academy of Sciences of the United States of America. 104: 8582-9. PMID 17494755 DOI: 10.1073/pnas.0701035104  1
2006 Gerhart J. The deuterostome ancestor. Journal of Cellular Physiology. 209: 677-85. PMID 17001683 DOI: 10.1002/jcp.20803  1
2006 Lowe CJ, Terasaki M, Wu M, Freeman RM, Runft L, Kwan K, Haigo S, Aronowicz J, Lander E, Gruber C, Smith M, Kirschner M, Gerhart J. Dorsoventral patterning in hemichordates: insights into early chordate evolution. Plos Biology. 4: e291. PMID 16933975 DOI: 10.1371/journal.pbio.0040291  1
2005 Gerhart J, Lowe C, Kirschner M. Hemichordates and the origin of chordates. Current Opinion in Genetics & Development. 15: 461-7. PMID 15964754 DOI: 10.1016/j.gde.2005.06.004  1
2005 Kirschner MW, Gerhart JC. The plausibility of life: Resolving Darwin's Dilemma The Plausibility of Life: Resolving Darwin's Dilemma. 1-314.  1
2004 Lowe CJ, Tagawa K, Humphreys T, Kirschner M, Gerhart J. Hemichordate embryos: procurement, culture, and basic methods. Methods in Cell Biology. 74: 171-94. PMID 15575607  1
2003 Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M. Anteroposterior patterning in hemichordates and the origins of the chordate nervous system. Cell. 113: 853-65. PMID 12837244 DOI: 10.1016/S0092-8674(03)00469-0  1
2002 Gerhart J. Changing the axis changes the perspective. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 380-3. PMID 12454916 DOI: 10.1002/dvdy.10198  1
2001 Gerhart J. Evolution of the organizer and the chordate body plan. The International Journal of Developmental Biology. 45: 133-53. PMID 11291842  1
2000 Gerhart J. Inversion of the chordate body axis: are there alternatives? Proceedings of the National Academy of Sciences of the United States of America. 97: 4445-8. PMID 10781041 DOI: 10.1073/pnas.97.9.4445  1
2000 Kirschner M, Gerhart J, Mitchison T. Molecular "vitalism". Cell. 100: 79-88. PMID 10647933  1
1999 Gerhart J. Pieter Nieuwkoop's contributions to the understanding of meso-endoderm induction and neural induction in chordate development. The International Journal of Developmental Biology. 43: 605-13. PMID 10668970  1
1999 Gerhart J. 1998 Warkany lecture: signaling pathways in development. Teratology. 60: 226-39. PMID 10508976 DOI: 10.1002/(SICI)1096-9926(199910)60:4<226::AID-TERA7>3.0.CO;2-W  1
1998 Kirschner M, Gerhart J. Evolvability. Proceedings of the National Academy of Sciences of the United States of America. 95: 8420-7. PMID 9671692 DOI: 10.1073/pnas.95.15.8420  1
1998 Sheets MD, Amersdorfer P, Finnern R, Sargent P, Lindquist E, Schier R, Hemingsen G, Wong C, Gerhart JC, Marks JD, Lindqvist E. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proceedings of the National Academy of Sciences of the United States of America. 95: 6157-62. PMID 9600934 DOI: 10.1073/pnas.95.11.6157  1
1997 Harland R, Gerhart J. Formation and function of Spemann's organizer. Annual Review of Cell and Developmental Biology. 13: 611-67. PMID 9442883 DOI: 10.1146/annurev.cellbio.13.1.611  1
1997 Zoltewicz JS, Gerhart JC. The Spemann organizer of Xenopus is patterned along its anteroposterior axis at the earliest gastrula stage. Developmental Biology. 192: 482-91. PMID 9441683 DOI: 10.1006/dbio.1997.8774  1
1997 Gerhart J. In memoriam Pieter D. Nieuwkoop (1917-1996). Developmental Biology. 182: 1-4. PMID 9073436  1
1997 Rowning BA, Wells J, Wu M, Gerhart JC, Moon RT, Larabell CA. Microtubule-mediated transport of organelles and localization of beta-catenin to the future dorsal side of Xenopus eggs. Proceedings of the National Academy of Sciences of the United States of America. 94: 1224-9. PMID 9037034 DOI: 10.1073/pnas.94.4.1224  1
1996 Gerhart J. Johannes Holtfreter's contributions to ongoing studies of the organizer. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 205: 245-56. PMID 8850561 DOI: 10.1002/(SICI)1097-0177(199603)205:3<245::AID-AJA5>3.0.CO;2-I  1
1996 Larabell CA, Rowning BA, Wells J, Wu M, Gerhart JC. Confocal microscopy analysis of living Xenopus eggs and the mechanism of cortical rotation. Development (Cambridge, England). 122: 1281-9. PMID 8620855  1
1995 Vodicka MA, Gerhart JC. Blastomere derivation and domains of gene expression in the Spemann Organizer of Xenopus laevis. Development (Cambridge, England). 121: 3505-18. PMID 8582265  1
1995 Gerhart J. Summing up: conservation and diversification in metazoan eukaryotic cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 349: 333-6. PMID 8577845 DOI: 10.1098/rstb.1995.0121  1
1994 Kroll KL, Gerhart JC. Transgenic X. laevis embryos from eggs transplanted with nuclei of transfected cultured cells. Science (New York, N.Y.). 266: 650-3. PMID 7939720  1
1994 Green JB, Smith JC, Gerhart JC. Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern. Development (Cambridge, England). 120: 2271-8. PMID 7925027  1
1994 Brickman MC, Gerhart JC. Heparitinase inhibition of mesoderm induction and gastrulation in Xenopus laevis embryos. Developmental Biology. 164: 484-501. PMID 7519155 DOI: 10.1006/dbio.1994.1218  1
1993 Hartman H, Wu M, Buchanan BB, Gerhart JC. Spinach thioredoxin m inhibits DNA synthesis in fertilized Xenopus eggs. Proceedings of the National Academy of Sciences of the United States of America. 90: 2271-5. PMID 8460133  1
1992 Doniach T, Phillips CR, Gerhart JC. Planar induction of anteroposterior pattern in the developing central nervous system of Xenopus laevis. Science (New York, N.Y.). 257: 542-5. PMID 1636091  1
1992 Roberts SJ, Leaf DS, Moore HP, Gerhart JC. The establishment of polarized membrane traffic in Xenopus laevis embryos. The Journal of Cell Biology. 118: 1359-69. PMID 1355772  1
1992 Akam M, Gerhart J. Pattern formation and developmental mechanisms Current Opinion in Genetics and Development. 2: 541-542.  1
1991 Ferrell JE, Wu M, Gerhart JC, Martin GS. Cell cycle tyrosine phosphorylation of p34cdc2 and a microtubule-associated protein kinase homolog in Xenopus oocytes and eggs. Molecular and Cellular Biology. 11: 1965-71. PMID 2005892  1
1991 Wu M, Gerhart J. Raising Xenopus in the laboratory. Methods in Cell Biology. 36: 3-18. PMID 1811140  0.32
1991 Wu M, Gerhart J. Chapter 1 Raising Xenopus in the Laboratory Methods in Cell Biology. 36: 3-18. DOI: 10.1016/S0091-679X(08)60269-1  1
1991 Stewart RM, Gerhart JC. Induction of notochord by the organizer in Xenopus Roux's Archives of Developmental Biology. 199: 341-348. DOI: 10.1007/BF01705927  1
1991 Akam M, Gerhart J. Editorial overview Current Opinion in Genetics and Development. 1: 167-168.  1
1990 Stewart RM, Gerhart JC. The anterior extent of dorsal development of the Xenopus embryonic axis depends on the quantity of organizer in the late blastula. Development (Cambridge, England). 109: 363-72. PMID 2401200  1
1990 Leaf DS, Roberts SJ, Gerhart JC, Moore HP. The secretory pathway is blocked between the trans-Golgi and the plasma membrane during meiotic maturation in Xenopus oocytes. Developmental Biology. 141: 1-12. PMID 2390997 DOI: 10.1016/0012-1606(90)90097-3  1
1989 Gerhart J, Danilchik M, Doniach T, Roberts S, Rowning B, Stewart R. Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development. Development (Cambridge, England). 107: 37-51. PMID 2699856  1
1989 Gerhart J. The primacy of cell interactions in development. Trends in Genetics : Tig. 5: 233-6. PMID 2686110 DOI: 10.1016/0168-9525(89)90093-0  1
1989 Scharf SR, Rowning B, Wu M, Gerhart JC. Hyperdorsoanterior embryos from Xenopus eggs treated with D2O. Developmental Biology. 134: 175-88. PMID 2659411 DOI: 10.1016/0012-1606(89)90087-0  1
1987 Vincent JP, Scharf SR, Gerhart JC. Subcortical rotation in Xenopus eggs: a preliminary study of its mechanochemical basis. Cell Motility and the Cytoskeleton. 8: 143-54. PMID 3690686 DOI: 10.1002/cm.970080206  1
1987 Vincent JP, Gerhart JC. Subcortical rotation in Xenopus eggs: an early step in embryonic axis specification. Developmental Biology. 123: 526-39. PMID 3653523 DOI: 10.1016/0012-1606(87)90411-8  1
1987 Danilchik MV, Gerhart JC. Differentiation of the animal-vegetal axis in Xenopus laevis oocytes. I. Polarized intracellular translocation of platelets establishes the yolk gradient. Developmental Biology. 122: 101-12. PMID 3596006 DOI: 10.1016/0012-1606(87)90336-8  1
1987 Gerhart JC. Determinants of early amphibian development Integrative and Comparative Biology. 27: 593-605. DOI: 10.1093/icb/27.2.593  1
1986 Vincent JP, Oster GF, Gerhart JC. Kinematics of gray crescent formation in Xenopus eggs: the displacement of subcortical cytoplasm relative to the egg surface. Developmental Biology. 113: 484-500. PMID 3949075 DOI: 10.1016/0012-1606(86)90184-3  1
1986 Vincent JP, Gerhart JC. A reinvestigation of the process of grey crescent formation in Xenopus eggs. Progress in Clinical and Biological Research. 217: 349-52. PMID 3749190  1
1986 Gerhart J, Keller R. Region-specific cell activities in amphibian gastrulation. Annual Review of Cell Biology. 2: 201-29. PMID 3548766 DOI: 10.1146/annurev.cb.02.110186.001221  1
1986 Black SD, Gerhart JC. High-frequency twinning of Xenopus laevis embryos from eggs centrifuged before first cleavage. Developmental Biology. 116: 228-40. PMID 3488238 DOI: 10.1016/0012-1606(86)90059-X  1
1986 Gerhart JC. Inside development Nature. 324: 178. DOI: 10.1038/324178a0  1
1985 Black SD, Gerhart JC. Experimental control of the site of embryonic axis formation in Xenopus laevis eggs centrifuged before first cleavage. Developmental Biology. 108: 310-24. PMID 4076537 DOI: 10.1016/0012-1606(85)90035-1  1
1985 Gerhart J, Wu M, Cyert M, Kirschner M. M-phase promoting factors from eggs of Xenopus laevis. Cytobios. 43: 335-47. PMID 3908000  1
1985 Kirschner M, Newport J, Gerhart J. The timing of early developmental events in Xenopus Trends in Genetics. 1: 41-47. DOI: 10.1016/0168-9525(85)90021-6  1
1984 Gerhart J, Wu M, Kirschner M. Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs. The Journal of Cell Biology. 98: 1247-55. PMID 6425302  1
1984 Garzón J, Sánchez-Blázquez P, Gerhart J, Loh HH, Lee NM. Dynorphin1-13: interaction with other opiate ligand bindings in vitro. Brain Research. 302: 392-6. PMID 6329465 DOI: 10.1016/0006-8993(84)90256-7  1
1984 Gimlich RL, Gerhart JC. Early cellular interactions promote embryonic axis formation in Xenopus laevis. Developmental Biology. 104: 117-30. PMID 6203792 DOI: 10.1016/0012-1606(84)90042-3  1
1984 Gerhart JC, Vincent JP, Scharf SR, Black SD, Gimlich RL, Danilchik M. Localization and induction in early development of Xenopus. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 319-30. PMID 6151704  1
1984 Garzón J, Sánchez-Blázquez P, Gerhart J, Loh HH, Lee NM. Dynorphin A: inhibitory effect on other opiate ligand bindings in the mouse brain. Biochemical Pharmacology. 33: 2609-14. PMID 6147144 DOI: 10.1016/0006-2952(84)90633-6  1
1983 Scharf SR, Gerhart JC. Axis determination in eggs of Xenopus laevis: a critical period before first cleavage, identified by the common effects of cold, pressure and ultraviolet irradiation. Developmental Biology. 99: 75-87. PMID 6684607 DOI: 10.1016/0012-1606(83)90255-5  1
1982 Tokunaga C, Sizemore S, Michinomae M, Gerhart JC. Pleiotropic effects in the four jointed mutant of Drosophila melanogaster Japanese Journal of Genetics. 57: 1-16.  1
1981 Gerhart J, Ubbels G, Black S, Hara K, Kirschner M. A reinvestigation of the role of the grey crescent in axis formation in xenopus laevis. Nature. 292: 511-6. PMID 7195987 DOI: 10.1038/292511a0  1
1980 Scharf SR, Gerhart JC. Determination of the dorsal-ventral axis in eggs of Xenopus laevis: complete rescue of uv-impaired eggs by oblique orientation before first cleavage. Developmental Biology. 79: 181-98. PMID 7409319  1
1980 Wu M, Gerhart JC. Partial purification and characterization of the maturation-promoting factor from eggs of Xenopus laevis. Developmental Biology. 79: 465-77. PMID 7000582  1
1980 Kirschner MW, Butner KA, Newport JW, Black SD, Scharf SR, Gerhart JC. Spatial and temporal changes in early amphibian development Netherlands Journal of Zoology. 31: 50-77. DOI: 10.1163/002829680X00195  1
1979 Thoman M, Gerhart JC. Absence of dorsal-ventral differences in energy metabolism in early embryos of Xenopus laevis. Developmental Biology. 68: 191-202. PMID 437316 DOI: 10.1016/0012-1606(79)90253-7  1
1977 Maller J, Wu M, Gerhart JC. Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes. Developmental Biology. 58: 295-312. PMID 885290 DOI: 10.1016/0012-1606(77)90093-8  1
1977 Semancik JS, Conejero V, Gerhart J. Citrus exocortis viroid: survey of protein synthesis in Xenopus laevis oocytes following addition of viroid RNA. Virology. 80: 218-21. PMID 560084 DOI: 10.1016/0042-6822(77)90395-6  1
1976 Maller J, Poccia D, Nishioka D, Kidd P, Gerhart J, Hartman H. Spindle formation and cleavage in Xenopus eggs injected with centriole-containing fractions from sperm. Experimental Cell Research. 99: 285-94. PMID 944633 DOI: 10.1016/0043-1354(76)90190-1  1
1976 Tokunaga C, Gerhart JC. The effect of growth and joint formation on bristle pattern in D. melanogaster. The Journal of Experimental Zoology. 198: 79-95. PMID 824401 DOI: 10.1002/jez.1401980110  1
1975 Wood FT, Wu MM, Gerhart JC. The radioactive labeling of proteins with an iodinated amidination reagent. Analytical Biochemistry. 69: 339-49. PMID 1217703 DOI: 10.1016/0003-2697(75)90136-0  1
1974 Kirschner MW, Williams RC, Weingarten M, Gerhart JC. Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly. Proceedings of the National Academy of Sciences of the United States of America. 71: 1159-63. PMID 4524627  1
1973 Laskey RA, Gerhart JC, Knowland JS. Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae of Xenopus laevis. Developmental Biology. 33: 241-8. PMID 4363801 DOI: 10.1016/0012-1606(73)90134-6  1
1973 Lee LW, Gerhart JC. Dependence of transdetermination frequency on the developmental stage of cultured imaginal discs of Drosophila melanogaster. Developmental Biology. 35: 62-82. PMID 4207112 DOI: 10.1016/0012-1606(73)90007-9  1
1972 Shodell M, Rubin H, Gerhart J. Neutralization of growth-inhibitory material present in calf serum by conditioning factors elaborated by chick embryo cells in culture. Experimental Cell Research. 74: 375-82. PMID 4673148 DOI: 10.1016/0014-4827(72)90390-4  1
1972 O'Donovan GA, Holoubek H, Gerhart JC. Regulatory properties of intergeneric hybrids of aspartate transcarbamylase. Nature: New Biology. 238: 264-6. PMID 4561861  1
1972 O'Donovan GA, Gerhart JC. Isolation and partial characterization of regulatory mutants of the pyrimidine pathway in Salmonella typhimurium. Journal of Bacteriology. 109: 1085-96. PMID 4551742  1
1972 Nelbach ME, Pigiet VP, Gerhart JC, Schachman HK. A role for zinc in the quaternary structure of aspartate transcarbamylase from Escherichia coli. Biochemistry. 11: 315-27. PMID 4550953  1
1968 Gerhart JC, Schachman HK. Allosteric interactions in aspartate transcarbamylase. II. Evidence for different conformational states of the protein in the presence and absence of specific ligands. Biochemistry. 7: 538-52. PMID 4868540  1
1967 Gerhart JC, Holoubek H. The purification of aspartate transcarbamylase of Escherichia coli and separation of its protein subunits. The Journal of Biological Chemistry. 242: 2886-92. PMID 5338508  1
1967 Gerhart JC. [18] Separation of subunits of proteins by zone centrifugation in a density gradient Methods in Enzymology. 11: 187-194. DOI: 10.1016/S0076-6879(67)11020-3  1
1965 Gerhart JC, Schachman HK. Distinct subunits for the regulation and catalytic activity of aspartate transcarbamylase. Biochemistry. 4: 1054-62. PMID 5320387  1
1962 GERHART JC, PARDEE AB. The enzymology of control by feedback inhibition. The Journal of Biological Chemistry. 237: 891-6. PMID 13897943  1
1961 RACHMELER M, GERHART J, ROSNER J. Limited thymidine uptake in Escherichia coli due to an inducible thymidine phosphorylase. Biochimica Et Biophysica Acta. 49: 222-5. PMID 13738908  1
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