Sanjay K. Nigam - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical

184 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Whisenant TC, Nigam SK. Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma. Cancers. 14. PMID 36230695 DOI: 10.3390/cancers14194772  0.319
2021 Granados JC, Nigam AK, Bush KT, Jamshidi N, Nigam SK. A key role for the transporter OAT1 in systemic lipid metabolism. The Journal of Biological Chemistry. 100603. PMID 33785360 DOI: 10.1016/j.jbc.2021.100603  0.601
2021 Granados JC, Richelle A, Gutierrez JM, Zhang P, Zhang X, Bhatnagar V, Lewis NE, Nigam SK. \Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3. The Journal of Biological Chemistry. 100575. PMID 33757768 DOI: 10.1016/j.jbc.2021.100575  0.31
2021 Torres AM, Dnyanmote AV, Granados JC, Nigam SK. Renal and non-renal response of ABC and SLC transporters in chronic kidney disease. Expert Opinion On Drug Metabolism & Toxicology. PMID 33749483 DOI: 10.1080/17425255.2021.1899159  0.306
2020 Bush KT, Singh P, Nigam SK. Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease. Jci Insight. 5. PMID 32271169 DOI: 10.1172/Jci.Insight.133817  0.684
2020 Engelhart DC, Azad P, Ali S, Granados JC, Haddad GG, Nigam SK. SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. International Journal of Molecular Sciences. 21. PMID 32183456 DOI: 10.3390/Ijms21062002  0.406
2020 Engelhart DC, Granados JC, Shi D, Saier Jr MH, Baker ME, Abagyan R, Nigam SK. Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs. International Journal of Molecular Sciences. 21. PMID 32150922 DOI: 10.3390/Ijms21051791  0.397
2020 Nigam SK, Bush KT, Bhatnagar V, Poloyac SM, Momper JD. The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology. Clinical Pharmacology and Therapeutics. PMID 32119114 DOI: 10.1002/Cpt.1818  0.67
2020 Nigam AK, Li JG, Lall K, Shi D, Bush KT, Bhatnagar V, Abagyan R, Nigam SK. Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning. The Journal of Biological Chemistry. PMID 31896576 DOI: 10.1074/Jbc.Ra119.010729  0.658
2019 Rosenthal SB, Bush KT, Nigam SK. A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis. Scientific Reports. 9: 11879. PMID 31417100 DOI: 10.1038/S41598-019-47798-X  0.667
2019 Momper JD, Yang J, Gockenbach M, Vaida F, Nigam SK. Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 30885911 DOI: 10.2215/Cjn.10350818  0.404
2019 Nigam SK, Bush KT. Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling. Nature Reviews. Nephrology. PMID 30728454 DOI: 10.1038/S41581-019-0111-1  0.65
2018 Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P. Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development. American Journal of Medical Genetics. Part A. PMID 30422383 DOI: 10.1002/Ajmg.A.40481  0.647
2018 Paquette A, Baloni P, Holloman A, Nigam S, Bammler T, Mao Q, Price ND. Temporal Transcriptomic Analysis of Metabolic Genes in Maternal Organs and Placenta During Murine Pregnancy. Biology of Reproduction. PMID 29939228 DOI: 10.1093/Biolre/Ioy148  0.326
2018 Nigam SK, Bhatnagar V. The systems biology of uric acid transporters: the role of remote sensing and signaling. Current Opinion in Nephrology and Hypertension. 27: 305-313. PMID 29847376 DOI: 10.1097/Mnh.0000000000000427  0.359
2018 Momper JD, Nigam SK. Developmental regulation of kidney and liver SLC and ABC drug transporters and drug metabolizing enzymes: the role of remote organ communication. Expert Opinion On Drug Metabolism & Toxicology. PMID 29746174 DOI: 10.1080/17425255.2018.1473376  0.418
2018 Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolić I, Vallon V. The organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin. American Journal of Physiology. Renal Physiology. PMID 29412698 DOI: 10.1152/Ajprenal.00503.2017  0.375
2018 Nigam SK. The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease. Annual Review of Pharmacology and Toxicology. 58: 663-687. PMID 29309257 DOI: 10.1146/Annurev-Pharmtox-010617-052713  0.406
2017 Bush KT, Wu W, Lun C, Nigam SK. The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis. The Journal of Biological Chemistry. PMID 28765282 DOI: 10.1074/Jbc.M117.796516  0.674
2017 Wu W, Bush KT, Nigam SK. Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes. Scientific Reports. 7: 4939. PMID 28694431 DOI: 10.1038/S41598-017-04949-2  0.674
2016 Liu HC, Goldenberg A, Chen Y, Lun C, Wu W, Bush KT, Balac N, Rodriguez P, Abagyan R, Nigam SK. Analysis of Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach. The Journal of Pharmacology and Experimental Therapeutics. PMID 27488918 DOI: 10.1124/Jpet.116.232660  0.63
2016 Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK. Construction and Evaluation of an Organic Anion Transporter 1 (OAT1)-Centered Metabolic Network. The Journal of Biological Chemistry. PMID 27440044 DOI: 10.1074/Jbc.M116.745216  0.67
2016 Bhatnagar V, Richard EL, Wu W, Nievergelt CM, Lipkowitz MS, Jeff J, Maihofer AX, Nigam SK. Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling. Clinical Kidney Journal. 9: 444-453. PMID 27274832 DOI: 10.1093/Ckj/Sfw010  0.414
2016 He X, Garza D, Nigam SK, Chang G. Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2. Plos One. 11: e0152969. PMID 27046168 DOI: 10.1371/Journal.Pone.0152969  0.378
2016 Martovetsky G, Bush KT, Nigam SK. Transcription factor-mediated regulation of kidney versus liver specification of Slc and Abc drug transporters, tight junction molecules and signature biomarkers. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27044799 DOI: 10.1124/Dmd.115.068254  0.696
2015 Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 4. PMID 26554899 DOI: 10.7554/Elife.08413  0.617
2015 Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Wu W, Nigam SK. Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. Plos One. 10: e0140569. PMID 26536134 DOI: 10.1371/Journal.Pone.0140569  0.648
2015 Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters. Clinical Journal of the American Society of Nephrology : Cjasn. 10: 2039-49. PMID 26490509 DOI: 10.2215/Cjn.02440314  0.68
2015 Wu W, Bush KT, Liu HC, Zhu C, Abagyan R, Nigam SK. Shared Ligands between Organic Anion Transporters (Oat1 and Oat6) and Odorant Receptors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26358290 DOI: 10.1124/Dmd.115.065250  0.645
2015 Eraly SA, Liu HC, Jamshidi N, Nigam SK. Transcriptome-based reconstructions from the murine knockout suggest involvement of the urate transporter, URAT1 (slc22a12), in novel metabolic pathways. Biochemistry and Biophysics Reports. 3: 51-61. PMID 26251846 DOI: 10.1016/J.Bbrep.2015.07.012  0.407
2015 Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clinical Pharmacology and Therapeutics. 98: 266-87. PMID 26088472 DOI: 10.1002/Cpt.176  0.337
2015 Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1859-68. PMID 25630970 DOI: 10.1096/Fj.14-257808  0.74
2015 Nigam SK, Bush KT, Martovetsky G, Ahn SY, Liu HC, Richard E, Bhatnagar V, Wu W. The organic anion transporter (OAT) family: a systems biology perspective. Physiological Reviews. 95: 83-123. PMID 25540139 DOI: 10.1152/Physrev.00025.2013  0.683
2015 Nigam SK. What do drug transporters really do? Nature Reviews. Drug Discovery. 14: 29-44. PMID 25475361 DOI: 10.1038/Nrd4461  0.346
2015 Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Author response: Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells Elife. DOI: 10.7554/Elife.08413.029  0.589
2014 Martovetsky G, Nigam SK. Cellular and developmental strategies aimed at kidney tissue engineering. Nephron. Experimental Nephrology. 126: 101. PMID 24854650 DOI: 10.1159/000360680  0.35
2014 Bush KT, Martovetsky G, Nigam SK. Relevance of ureteric bud development and branching to tissue engineering, regeneration and repair in acute and chronic kidney disease. Current Opinion in Organ Transplantation. 19: 153-61. PMID 24503495 DOI: 10.1097/Mot.0000000000000053  0.661
2014 Nigam SK, Bush KT. Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis. Pediatric Nephrology (Berlin, Germany). 29: 727-35. PMID 24488503 DOI: 10.1007/S00467-013-2725-Z  0.67
2014 Bush KT, Nagle M, Truong DM, Bhatnagar V, Kaler G, Eraly SA, Wu W, Nigam SK. Organic Anion Transporters Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 25-41. DOI: 10.1002/9781118705308.ch3  0.599
2013 Nigam SK. Concise review: can the intrinsic power of branching morphogenesis be used for engineering epithelial tissues and organs? Stem Cells Translational Medicine. 2: 993-1000. PMID 24191267 DOI: 10.5966/Sctm.2013-0076  0.364
2013 Tee JB, Choi Y, Dnyanmote A, Decambre M, Ito C, Bush KT, Nigam SK. GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling. Biology Open. 2: 952-9. PMID 24143282 DOI: 10.1242/Bio.20135595  0.763
2013 Martovetsky G, Tee JB, Nigam SK. Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters. Molecular Pharmacology. 84: 808-23. PMID 24038112 DOI: 10.1124/Mol.113.088229  0.457
2013 Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, ... ... Nigam SK, et al. Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. Journal of the American Society of Nephrology : Jasn. 24: 1901-12. PMID 23949796 DOI: 10.1681/Asn.2013020126  0.322
2013 Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1825-34. PMID 23920220 DOI: 10.1124/Dmd.113.052647  0.664
2013 Nigam SK, Bhatnagar V. How much do we know about drug handling by SLC and ABC drug transporters in children? Clinical Pharmacology and Therapeutics. 94: 27-29. PMID 23778708 DOI: 10.1038/Clpt.2013.82  0.33
2013 Nagle MA, Wu W, Eraly SA, Nigam SK. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue. Neuroscience Letters. 534: 133-8. PMID 23196129 DOI: 10.1016/J.Neulet.2012.11.027  0.405
2013 Bush KT, Sakurai H, Nigam SK. Molecular and Cellular Mechanisms of Kidney Development Seldin and Geibisch's the Kidney. 1: 859-890. DOI: 10.1016/B978-0-12-381462-3.00025-2  0.609
2012 Bush KT, Crawford BE, Garner OB, Nigam KB, Esko JD, Nigam SK. N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland. The Journal of Biological Chemistry. 287: 42064-70. PMID 23060443 DOI: 10.1074/Jbc.M112.423327  0.628
2012 Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule. Plos One. 7: e40796. PMID 22808265 DOI: 10.1371/Journal.Pone.0040796  0.826
2012 Zhang X, Bush KT, Nigam SK. In vitro culture of embryonic kidney rudiments and isolated ureteric buds. Methods in Molecular Biology (Clifton, N.J.). 886: 13-21. PMID 22639247 DOI: 10.1007/978-1-61779-851-1_2  0.624
2012 Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. American Journal of Physiology. Renal Physiology. 302: F1293-9. PMID 22338083 DOI: 10.1152/Ajprenal.00013.2012  0.393
2012 Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Developmental Biology. 364: 11-21. PMID 22290330 DOI: 10.1016/J.Ydbio.2012.01.014  0.81
2011 Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK. Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. The Journal of Biological Chemistry. 286: 31522-31. PMID 21757732 DOI: 10.1074/Jbc.M111.272534  0.793
2011 Torres AM, Dnyanmote AV, Bush KT, Wu W, Nigam SK. Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury. The Journal of Biological Chemistry. 286: 26391-5. PMID 21652719 DOI: 10.1074/Jbc.M111.249292  0.653
2011 Shah MM, Sakurai H, Gallegos TF, Sweeney DE, Bush KT, Esko JD, Nigam SK. Growth factor-dependent branching of the ureteric bud is modulated by selective 6-O sulfation of heparan sulfate. Developmental Biology. 356: 19-27. PMID 21600196 DOI: 10.1016/J.Ydbio.2011.05.004  0.792
2011 Garner OB, Bush KT, Nigam KB, Yamaguchi Y, Xu D, Esko JD, Nigam SK. Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Developmental Biology. 355: 394-403. PMID 21586278 DOI: 10.1016/J.Ydbio.2011.04.035  0.683
2011 Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK. Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1). Bioorganic & Medicinal Chemistry. 19: 3320-40. PMID 21571536 DOI: 10.1016/J.Bmc.2011.04.045  0.367
2011 Tsigelny IF, Kovalskyy D, Kouznetsova VL, Balinskyi O, Sharikov Y, Bhatnagar V, Nigam SK. Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport. Cell Biochemistry and Biophysics. 61: 251-9. PMID 21499753 DOI: 10.1007/S12013-011-9191-7  0.378
2011 Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Molecular Pharmacology. 80: 147-54. PMID 21493727 DOI: 10.1124/Mol.110.070680  0.788
2011 Wikoff WR, Nagle MA, Kouznetsova VL, Tsigelny IF, Nigam SK. Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). Journal of Proteome Research. 10: 2842-51. PMID 21476605 DOI: 10.1021/Pr200093W  0.39
2011 Wu W, Dnyanmote AV, Nigam SK. Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis. Molecular Pharmacology. 79: 795-805. PMID 21325265 DOI: 10.1124/Mol.110.070607  0.4
2011 Sweeney DE, Gallegos TF, Dnyanmote AV, Zhang X, Nigam SK. Branching morphogenesis: from individual molecules to a systems biology approach: commentary on "Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney" by Perälä et al. Differentiation; Research in Biological Diversity. 81: 79-80. PMID 21168258 DOI: 10.1016/J.Diff.2010.11.004  0.749
2011 Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, Nigam SK. Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling. The Journal of Biological Chemistry. 286: 243-51. PMID 20921221 DOI: 10.1074/Jbc.M110.139949  0.383
2010 Tee JB, Choi Y, Shah MM, Dnyanmote A, Sweeney DE, Gallegos TF, Johkura K, Ito C, Bush KT, Nigam SK. Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct. Developmental Biology. 347: 337-47. PMID 20816800 DOI: 10.1016/J.Ydbio.2010.08.029  0.796
2010 Crawford BE, Garner OB, Bishop JR, Zhang DY, Bush KT, Nigam SK, Esko JD. Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice. Plos One. 5: e10691. PMID 20502530 DOI: 10.1371/Journal.Pone.0010691  0.655
2010 Rosines E, Johkura K, Zhang X, Schmidt HJ, Decambre M, Bush KT, Nigam SK. Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney. Tissue Engineering. Part A. 16: 2441-55. PMID 20214453 DOI: 10.1089/Ten.Tea.2009.0548  0.677
2010 Shah MM, Sakurai H, Sweeney DE, Gallegos TF, Bush KT, Esko JD, Nigam SK. Hs2st mediated kidney mesenchyme induction regulates early ureteric bud branching. Developmental Biology. 339: 354-65. PMID 20059993 DOI: 10.1016/J.Ydbio.2009.12.033  0.808
2010 Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK. The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects (American Journal Physiology-Renal Physiology (2009) 297, (F1330-F1341)) American Journal of Physiology - Renal Physiology. 298: F1285. DOI: 10.1152/ajprenal.zh2-5897-corr.2010  0.738
2009 Choi Y, Tee JB, Gallegos TF, Shah MM, Oishi H, Sakurai H, Kitamura S, Wu W, Bush KT, Nigam SK. Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct. Development (Cambridge, England). 136: 4213-24. PMID 19934016 DOI: 10.1242/Dev.037580  0.793
2009 Ahn SY, Eraly SA, Tsigelny I, Nigam SK. Interaction of organic cations with organic anion transporters. The Journal of Biological Chemistry. 284: 31422-30. PMID 19737926 DOI: 10.1074/Jbc.M109.024489  0.355
2009 Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK. The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects. American Journal of Physiology. Renal Physiology. 297: F1330-41. PMID 19726549 DOI: 10.1152/Ajprenal.00125.2009  0.802
2009 Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nature Medicine. 15: 1046-54. PMID 19718039 DOI: 10.1038/Nm.2010  0.394
2009 Ahn SY, Nigam SK. Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Molecular Pharmacology. 76: 481-90. PMID 19515966 DOI: 10.1124/Mol.109.056564  0.415
2009 Wu W, Kitamura S, Truong DM, Rieg T, Vallon V, Sakurai H, Bush KT, Vera DR, Ross RS, Nigam SK. Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. American Journal of Physiology. Renal Physiology. 297: F210-7. PMID 19439520 DOI: 10.1152/Ajprenal.90260.2008  0.667
2009 Wu W, Baker ME, Eraly SA, Bush KT, Nigam SK. Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiological Genomics. 38: 116-24. PMID 19417012 DOI: 10.1152/Physiolgenomics.90309.2008  0.65
2009 Nigam SK, Shah MM. How does the ureteric bud branch? Journal of the American Society of Nephrology : Jasn. 20: 1465-9. PMID 19056872 DOI: 10.1681/Asn.2008020132  0.411
2008 Nigam SK, Wu W, Bush KT. Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology. Organogenesis. 4: 137-43. PMID 19279725 DOI: 10.4161/Org.4.3.6498  0.661
2008 Tsigelny IF, Kouznetsova VL, Sweeney DE, Wu W, Bush KT, Nigam SK. Analysis of metagene portraits reveals distinct transitions during kidney organogenesis. Science Signaling. 1: ra16. PMID 19066399 DOI: 10.1126/Scisignal.1163630  0.646
2008 Tsigelny IF, Greenberg J, Kouznetsova V, Nigam SK. Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function. Journal of Bioinformatics and Computational Biology. 6: 885-904. PMID 18942157 DOI: 10.1142/S0219720008003801  0.346
2008 Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. Journal of the American Society of Nephrology : Jasn. 19: 1732-40. PMID 18508962 DOI: 10.1681/Asn.2008020180  0.37
2008 Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiological Genomics. 33: 180-92. PMID 18270321 DOI: 10.1152/Physiolgenomics.00207.2007  0.406
2008 Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK. Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. American Journal of Physiology. Renal Physiology. 294: F867-73. PMID 18216144 DOI: 10.1152/Ajprenal.00528.2007  0.436
2008 Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. The Journal of Biological Chemistry. 283: 8654-63. PMID 18174163 DOI: 10.1074/Jbc.M708615200  0.393
2007 Rosines E, Sampogna RV, Johkura K, Vaughn DA, Choi Y, Sakurai H, Shah MM, Nigam SK. Staged in vitro reconstitution and implantation of engineered rat kidney tissue. Proceedings of the National Academy of Sciences of the United States of America. 104: 20938-43. PMID 18087037 DOI: 10.1073/Pnas.0710428105  0.661
2007 Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK. Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct. Journal of the American Society of Nephrology : Jasn. 18: 3147-55. PMID 18003772 DOI: 10.1681/Asn.2007060642  0.663
2007 Rosines E, Schmidt HJ, Nigam SK. The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissues. Biomaterials. 28: 4806-17. PMID 17706761 DOI: 10.1016/J.Biomaterials.2007.07.034  0.404
2007 Nigam SK, Bush KT, Bhatnagar V. Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues. Nature Clinical Practice. Nephrology. 3: 443-8. PMID 17653123 DOI: 10.1038/Ncpneph0558  0.679
2007 Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of Biological Chemistry. 282: 23841-53. PMID 17553798 DOI: 10.1074/Jbc.M703467200  0.367
2007 Monte JC, Sakurai H, Bush KT, Nigam SK. The developmental nephrome: systems biology in the developing kidney. Current Opinion in Nephrology and Hypertension. 16: 3-9. PMID 17143064 DOI: 10.1097/Mnh.0B013E3280118A5A  0.673
2007 Sakurai H, Bush KT, Kitamura S, Nigam SK. Differential regulation of tip and stalk of the branching ureteric bud The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A141-B  0.63
2006 Meyer TN, Schwesinger C, Sampogna RV, Vaughn DA, Stuart RO, Steer DL, Bush KT, Nigam SK. Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development. Differentiation; Research in Biological Diversity. 74: 638-47. PMID 17177859 DOI: 10.1111/J.1432-0436.2006.00102.X  0.69
2006 Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, Nigam SK. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochemical and Biophysical Research Communications. 351: 872-6. PMID 17094945 DOI: 10.1016/J.Bbrc.2006.10.136  0.335
2006 Bush KT, Vaughn DA, Li X, Rosenfeld MG, Rose DW, Mendoza SA, Nigam SK. Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system. Developmental Biology. 298: 571-84. PMID 16934795 DOI: 10.1016/J.Ydbio.2006.07.006  0.695
2006 Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). Journal of Human Genetics. 51: 575-80. PMID 16648942 DOI: 10.1007/S10038-006-0398-1  0.358
2006 Maeshima A, Vaughn DA, Choi Y, Nigam SK. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Developmental Biology. 295: 473-85. PMID 16643884 DOI: 10.1016/J.Ydbio.2006.03.011  0.665
2006 Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney International. 69: 837-45. PMID 16518343 DOI: 10.1038/Sj.Ki.5000170  0.698
2006 Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. The Journal of Biological Chemistry. 281: 5072-83. PMID 16354673 DOI: 10.1074/Jbc.M508050200  0.418
2006 Maeshima A, Sakurai H, Nigam SK. Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney. Journal of the American Society of Nephrology : Jasn. 17: 188-98. PMID 16338966 DOI: 10.1681/Asn.2005040370  0.421
2005 Sakurai H, Bush KT, Nigam SK. Heregulin induces glial cell line-derived neurotrophic growth factor-independent, non-branching growth and differentiation of ureteric bud epithelia. The Journal of Biological Chemistry. 280: 42181-7. PMID 16183643 DOI: 10.1074/Jbc.M507962200  0.68
2005 Xu G, Bhatnagar V, Wen G, Hamilton BA, Eraly SA, Nigam SK. Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)]. Kidney International. 68: 1491-9. PMID 16164626 DOI: 10.1111/J.1523-1755.2005.00612.X  0.402
2004 Sampogna RV, Nigam SK. Implications of gene networks for understanding resilience and vulnerability in the kidney branching program. Physiology (Bethesda, Md.). 19: 339-47. PMID 15546851 DOI: 10.1152/Physiol.00025.2004  0.363
2004 Meyer TN, Schwesinger C, Bush KT, Stuart RO, Rose DW, Shah MM, Vaughn DA, Steer DL, Nigam SK. Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney. Developmental Biology. 275: 44-67. PMID 15464572 DOI: 10.1016/J.Ydbio.2004.07.022  0.7
2004 Monte JC, Nagle MA, Eraly SA, Nigam SK. Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa. Biochemical and Biophysical Research Communications. 323: 429-36. PMID 15369770 DOI: 10.1016/J.Bbrc.2004.08.112  0.406
2004 George SK, Meyer TN, Abdeen O, Bush KT, Nigam SK. Tunicamycin preserves intercellular junctions, cytoarchitecture, and cell-substratum interactions in ATP-depleted epithelial cells. Biochemical and Biophysical Research Communications. 322: 223-31. PMID 15313195 DOI: 10.1016/J.Bbrc.2004.07.097  0.644
2004 Steer DL, Shah MM, Bush KT, Stuart RO, Sampogna RV, Meyer TN, Schwesinger C, Bai X, Esko JD, Nigam SK. Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney. Developmental Biology. 272: 310-27. PMID 15282150 DOI: 10.1016/J.Ydbio.2004.04.029  0.709
2004 Tsigelny IF, Nigam SK. Complex dynamics of chaperone-protein interactions under cellular stress. Cell Biochemistry and Biophysics. 40: 263-76. PMID 15211027 DOI: 10.1385/Cbb:40:3:263  0.311
2004 Chen D, Roberts R, Pohl M, Nigam S, Kreidberg J, Wang Z, Heino J, Ivaska J, Coffa S, Harris RC, Pozzi A, Zent R. Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis American Journal of Physiology - Renal Physiology. 287: F602-F611. PMID 15187002 DOI: 10.1152/Ajprenal.00015.2004  0.342
2004 Sykes D, Sweet DH, Lowes S, Nigam SK, Pritchard JB, Miller DS. Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. American Journal of Physiology. Renal Physiology. 286: F972-8. PMID 15075193 DOI: 10.1152/Ajprenal.00356.2003  0.367
2004 Eraly SA, Monte JC, Nigam SK. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiological Genomics. 18: 12-24. PMID 15054140 DOI: 10.1152/Physiolgenomics.00014.2004  0.396
2004 Shah MM, Sampogna RV, Sakurai H, Bush KT, Nigam SK. Branching morphogenesis and kidney disease. Development (Cambridge, England). 131: 1449-62. PMID 15023929 DOI: 10.1242/Dev.01089  0.657
2004 Eraly SA, Bush KT, Sampogna RV, Bhatnagar V, Nigam SK. The molecular pharmacology of organic anion transporters: from DNA to FDA? Molecular Pharmacology. 65: 479-87. PMID 14978224 DOI: 10.1124/Mol.65.3.479  0.656
2004 Bush KT, Sakurai H, Steer DL, Leonard MO, Sampogna RV, Meyer TN, Schwesinger C, Qiao J, Nigam SK. TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud. Developmental Biology. 266: 285-98. PMID 14738877 DOI: 10.1016/J.Ydbio.2003.10.023  0.648
2004 Steer DL, Nigam SK. Developmental approaches to kidney tissue engineering. American Journal of Physiology. Renal Physiology. 286: F1-7. PMID 14656756 DOI: 10.1152/Ajprenal.00167.2003  0.383
2004 Li X, Ohgi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Erratum: Corrigendum: Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis Nature. 427: 265-265. DOI: 10.1038/Nature02283  0.601
2003 Nigam SK. From the ureteric bud to the penome. Kidney International. 64: 2320-2. PMID 14633158 DOI: 10.1046/J.1523-1755.2003.00397.X  0.342
2003 Stuart RO, Bush KT, Nigam SK. Changes in gene expression patterns in the ureteric bud and metanephric mesenchyme in models of kidney development. Kidney International. 64: 1997-2008. PMID 14633122 DOI: 10.1046/J.1523-1755.2003.00383.X  0.682
2003 Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 426: 247-54. PMID 14628042 DOI: 10.1038/Nature02083  0.648
2003 Eraly SA, Blantz RC, Bhatnagar V, Nigam SK. Novel aspects of renal organic anion transporters. Current Opinion in Nephrology and Hypertension. 12: 551-8. PMID 12920404 DOI: 10.1097/00041552-200309000-00011  0.407
2003 Keller SH, Nigam SK. Biochemical processing of E-cadherin under cellular stress. Biochemical and Biophysical Research Communications. 307: 215-23. PMID 12859942 DOI: 10.1016/S0006-291X(03)01143-4  0.333
2003 Li Z, Stuart RO, Eraly SA, Gittes G, Beier DR, Nigam SK. Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis. Biochemical and Biophysical Research Communications. 306: 623-8. PMID 12810064 DOI: 10.1016/S0006-291X(03)00875-1  0.408
2003 Eraly SA, Hamilton BA, Nigam SK. Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochemical and Biophysical Research Communications. 300: 333-42. PMID 12504088 DOI: 10.1016/S0006-291X(02)02853-X  0.373
2002 Steer DL, Bush KT, Meyer TN, Schwesinger C, Nigam SK. A strategy for in vitro propagation of rat nephrons. Kidney International. 62: 1958-65. PMID 12427120 DOI: 10.1046/J.1523-1755.2002.00694.X  0.593
2002 Eraly SA, Nigam SK. Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochemical and Biophysical Research Communications. 297: 1159-66. PMID 12372408 DOI: 10.1016/S0006-291X(02)02343-4  0.378
2002 Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. The Journal of Biological Chemistry. 277: 26934-43. PMID 12011098 DOI: 10.1074/Jbc.M203803200  0.409
2002 Pohl M, Bhatnagar V, Mendoza SA, Nigam SK. Toward an etiological classification of developmental disorders of the kidney and upper urinary tract. Kidney International. 61: 10-9. PMID 11786080 DOI: 10.1046/J.1523-1755.2002.00086.X  0.326
2001 Zent R, Bush KT, Pohl ML, Quaranta V, Koshikawa N, Wang Z, Kreidberg JA, Sakurai H, Stuart RO, Nigám SK. Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development Developmental Biology. 238: 289-302. PMID 11784011 DOI: 10.1006/Dbio.2001.0391  0.641
2001 Qiao J, Bush KT, Steer DL, Stuart RO, Sakurai H, Wachsman W, Nigam SK. Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis Mechanisms of Development. 109: 123-135. PMID 11731227 DOI: 10.1016/S0925-4773(01)00592-5  0.653
2001 Stuart RO, Pavlova A, Beier D, Li Z, Krijanovski Y, Nigam SK. EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis. American Journal of Physiology. Renal Physiology. 281: F1148-56. PMID 11704567 DOI: 10.1152/Ajprenal.2001.281.6.F1148  0.399
2001 Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proceedings of the National Academy of Sciences of the United States of America. 98: 12509-14. PMID 11606725 DOI: 10.1073/Pnas.221205198  0.681
2001 Sakurai H, Bush KT, Nigam SK. Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis Development. 128: 3283-3293. PMID 11546745  0.308
2001 Sweet DH, Bush KT, Nigam SK. The organic anion transporter family: From physiology to ontogeny and the clinic American Journal of Physiology - Renal Physiology. 281: F197-F205. PMID 11457711 DOI: 10.1152/Ajprenal.2001.281.2.F197  0.659
2001 Saha C, Nigam SK, Denker BM. Expanding role of G proteins in tight junction regulation: Gα s stimulates TJ assembly Biochemical and Biophysical Research Communications. 285: 250-256. PMID 11444833 DOI: 10.1006/Bbrc.2001.5154  0.335
2001 Stuart RO, Bush KT, Nigam SK. Changes in global gene expression patterns during development and maturation of the rat kidney Proceedings of the National Academy of Sciences of the United States of America. 98: 5649-5654. PMID 11331749 DOI: 10.1073/Pnas.091110798  0.662
2001 Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Molecular and Cellular Biology. 21: 765-70. PMID 11154264 DOI: 10.1128/Mcb.21.3.765-770.2001  0.633
2001 Nigam SK, Bush KT. Folding and bioassembly of secretory proteins in health and disease Kidney International. 60: 397. DOI: 10.1046/J.1523-1755.2001.00821-3.X  0.569
2000 Pohl M, Sakurai H, Bush KT, Nigam SK. Matrix metalloproteinases and their inhibitors regulate in vitro ureteric bud branching morphogenesis American Journal of Physiology - Renal Physiology. 279: F891-F900. PMID 11053050 DOI: 10.1152/Ajprenal.2000.279.5.F891  0.607
2000 Bush KT, Keller SH, Nigam SK. Genesis and reversal of the ischemic phenotype in epithelial cells Journal of Clinical Investigation. 106: 621-626. PMID 10974012 DOI: 10.1172/Jci10968  0.669
2000 Li Z, Stuart RO, Qiao J, Pavlova A, Bush KT, Pohl M, Sakurai H, Nigam SK. A role for timeless in epithelial morphogenesis during kidney development Proceedings of the National Academy of Sciences of the United States of America. 97: 10038-10043. PMID 10963667 DOI: 10.1073/Pnas.97.18.10038  0.714
2000 Pohl M, Sakurai H, Stuart RO, Nigam SK. Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells Developmental Biology. 224: 312-325. PMID 10926769 DOI: 10.1006/Dbio.2000.9783  0.361
2000 Nigam SK, Lieberthal W. Acute renal failure. III. The role of growth factors in the process of renal regeneration and repair American Journal of Physiology - Renal Physiology. 279: F3-F11. PMID 10894783 DOI: 10.1152/Ajprenal.2000.279.1.F3  0.36
2000 Pohl M, Stuart RO, Sakurai H, Nigam SK. Branching morphogenesis during kidney development Annual Review of Physiology. 62: 595-620. PMID 10845104 DOI: 10.1146/Annurev.Physiol.62.1.595  0.443
2000 Bush KT, Tsukamoto T, Nigam SK. Selective degradation of E-cadherin and dissolution of E-cadherin- catenin complexes in epithelial ischemia American Journal of Physiology - Renal Physiology. 278: F847-F852. PMID 10807598 DOI: 10.1152/Ajprenal.2000.278.5.F847  0.627
2000 Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK. Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. American Journal of Physiology. Renal Physiology. 278: F635-43. PMID 10751225 DOI: 10.1152/Ajprenal.2000.278.4.F635  0.447
2000 Lieberthal W, Nigam SK. Acute renal failure. II. Experimental models of acute renal failure: Imperfect but indispensable American Journal of Physiology - Renal Physiology. 278: F1-F12. PMID 10644651 DOI: 10.1152/Ajprenal.2000.278.1.F1  0.327
1999 Pavlova A, Stuart RO, Pohl M, Nigam SK. Evolution of gene expression patterns in a model of branching morphogenesis American Journal of Physiology - Renal Physiology. 277: F650-F663. PMID 10516290 DOI: 10.1152/Ajprenal.1999.277.4.F650  0.41
1999 Ye J, Tsukamoto T, Sun A, Nigam SK. A role for intracellular calcium in tight junction reassembly after ATP depletion-repletion American Journal of Physiology - Renal Physiology. 277: F524-F532. PMID 10516276 DOI: 10.1152/Ajprenal.1999.277.4.F524  0.305
1999 Tsukamoto T, Nigam SK. Cell-cell dissociation upon epithelial cell scattering requires a step mediated by the proteasome Journal of Biological Chemistry. 274: 24579-24584. PMID 10455122 DOI: 10.1074/Jbc.274.35.24579  0.324
1999 Bush KT, George SK, Zhang PL, Nigam SK. Pretreatment with inducers of ER molecular chaperones protects epithelial cells subjected to ATP depletion American Journal of Physiology - Renal Physiology. 277: F211-F218. PMID 10444575 DOI: 10.1152/Ajprenal.1999.277.2.F211  0.644
1999 Qiao J, Sakurai H, Nigam SK. Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney Proceedings of the National Academy of Sciences of the United States of America. 96: 7330-7335. PMID 10377414 DOI: 10.1073/Pnas.96.13.7330  0.433
1999 Tsukamoto T, Nigam SK. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins American Journal of Physiology - Renal Physiology. 276: F737-F750. PMID 10330056 DOI: 10.1152/Ajprenal.1999.276.5.F737  0.304
1999 O'Rourke DA, Sakurai H, Spokes K, Kjelsberg C, Takahashi M, Nigam S, Cantley L. Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells. The American Journal of Physiology. 276: F581-8. PMID 10198418 DOI: 10.1152/Ajprenal.1999.276.4.F581  0.343
1999 Bush KT, Nigam SK. Less degradation, more shock, please Gastroenterology. 116: 994-996. PMID 10092324 DOI: 10.1016/S0016-5085(99)70085-5  0.549
1998 Kuznetsov G, Nigam SK. Folding of secretory and membrane proteins New England Journal of Medicine. 339: 1688-1695. PMID 9834307 DOI: 10.1056/Nejm199812033392307  0.318
1998 Lieberthal W, Nigam SK. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury American Journal of Physiology - Renal Physiology. 275: F623-F631. PMID 9815122 DOI: 10.1152/Ajprenal.1998.275.5.F623  0.311
1998 Saha C, Nigam SK, Denker BM. Involvement of Gα(i2) in the maintenance and biogenesis of epithelial cell tight junctions Journal of Biological Chemistry. 273: 21629-21633. PMID 9705295 DOI: 10.1074/Jbc.273.34.21629  0.341
1998 Sakurai H, Nigam SK. In vitro branching tubulogenesis: Implications for developmental and cystic disorders, nephron number, renal repair, and nephron engineering Kidney International. 54: 14-26. PMID 9648059 DOI: 10.1046/J.1523-1755.1998.00969.X  0.408
1998 Denker BM, Nigam SK. Molecular structure and assembly of the tight junction American Journal of Physiology - Renal Physiology. 274: F1-F9. PMID 9458817 DOI: 10.1152/Ajprenal.1998.274.1.F1  0.387
1997 Sakurai H, Tsukamoto T, Kjelsberg CA, Cantley LG, Nigam SK. EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney American Journal of Physiology - Renal Physiology. 273: F463-F472. PMID 9321921 DOI: 10.1152/Ajprenal.1997.273.3.F463  0.389
1997 Tsukamoto T, Nigam SK. Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly Journal of Biological Chemistry. 272: 16133-16139. PMID 9195909 DOI: 10.1074/Jbc.272.26.16133  0.334
1997 Sakurai H, Barros EJ, Tsukamoto T, Barasch J, Nigam SK. An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors Proceedings of the National Academy of Sciences of the United States of America. 94: 6279-6284. PMID 9177208 DOI: 10.1073/Pnas.94.12.6279  0.366
1997 Geng L, Segal Y, Pavlova A, Barros EJ, Löhning C, Lu W, Nigam SK, Frischauf AM, Reeders ST, Zhou J. Distribution and developmentally regulated expression of murine polycystin. The American Journal of Physiology. 272: F451-9. PMID 9140045 DOI: 10.1152/Ajprenal.1997.272.4.F451  0.409
1997 Kjelsberg C, Sakurai H, Spokes K, Birchmeier C, Drummond I, Nigam S, Cantley LG. Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands American Journal of Physiology-Renal Physiology. 272. PMID 9124399 DOI: 10.1152/Ajprenal.1997.272.2.F222  0.391
1997 Bush KT, Goldberg AL, Nigam SK. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance Journal of Biological Chemistry. 272: 9086-9092. PMID 9083035 DOI: 10.1074/Jbc.272.14.9086  0.614
1997 Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. The Journal of Biological Chemistry. 272: 6471-8. PMID 9045672 DOI: 10.1074/Jbc.272.10.6471  0.697
1997 Sakurai H, Nigam SK. Transforming growth factor-β selectively inhibits branching morphogenesis but not tubulogenesis American Journal of Physiology - Renal Physiology. 272: F139-F146. PMID 9039060 DOI: 10.1152/Ajprenal.1997.272.1.F139  0.329
1997 Kuznetsov G, Chen LB, Nigam SK. Multiple molecular chaperones complex with misfolded large oligomeric glycoproteins in the endoplasmic reticulum Journal of Biological Chemistry. 272: 3057-3063. PMID 9006956 DOI: 10.1074/Jbc.272.5.3057  0.307
1996 Kuznetsov G, Bush KT, Zhang PL, Nigam SK. Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia Proceedings of the National Academy of Sciences of the United States of America. 93: 8584-8589. PMID 8710914 DOI: 10.1073/Pnas.93.16.8584  0.648
1996 Stuart RO, Sun A, Bush KT, Nigam SK. Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores Journal of Biological Chemistry. 271: 13636-13641. PMID 8662885 DOI: 10.1074/Jbc.271.23.13636  0.629
1995 Stuart RO, Barros EJG, Ribeiro E, Nigam SK. Epithelial tubulogenesis through branching morphogenesis: Relevance to collecting system development Journal of the American Society of Nephrology. 6: 1151-1159. PMID 8589281  0.31
1995 Barros EJG, Santos OFP, Matsumoto K, Nakamura T, Nigam SK. Differential tubulogenic and branching morphogenetic activities of growth factors: Implications for epithelial tissue development Proceedings of the National Academy of Sciences of the United States of America. 92: 4412-4416. PMID 7753820 DOI: 10.1073/Pnas.92.10.4412  0.369
1995 Derman MP, Cunha MJ, Barros EJG, Nigam SK, Cantley LG. HGF-mediated chemotaxis and tubulogenesis require activation of the phosphatidylinositol 3-kinase American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268: F1211-F1217. PMID 7611461 DOI: 10.1152/Ajprenal.1995.268.6.F1211  0.356
1995 Stuart RO, Nigam SK. Regulated assembly of tight junctions by protein kinase C Proceedings of the National Academy of Sciences of the United States of America. 92: 6072-6076. PMID 7597083 DOI: 10.1073/Pnas.92.13.6072  0.325
1995 Stuart RO, Nigam SK. Development of the tubular nephron Seminars in Nephrology. 15: 315-326. PMID 7569411  0.323
1995 You G, Lee WS, Barros EJG, Kanai Y, Huo TL, Khawaja S, Wells RG, Nigam SK, Hediger MA. Molecular characteristics of Na+-coupled glucose transporters in adult and embryonic rat kidney Journal of Biological Chemistry. 270: 29365-29371. PMID 7493971 DOI: 10.1074/Jbc.270.49.29365  0.367
1995 Nigam S. Forefronts in Nephrology: The molecular basis of renal cystic disease Kidney International. 47: 717-718. DOI: 10.1038/Ki.1995.91  0.326
1994 Santos OFP, Barros EJG, Yang XM, Matsumoto K, Nakamura T, Park M, Nigam SK. Involvement of hepatocyte growth factor in kidney development Developmental Biology. 163: 525-529. PMID 8200486 DOI: 10.1006/Dbio.1994.1169  0.426
1994 Bush KT, Hendrickson BA, Nigam SK. Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum Biochemical Journal. 303: 705-708. PMID 7526846 DOI: 10.1042/Bj3030705  0.617
1994 Cantley LG, Barros EJG, Gandhi M, Rauchman M, Nigam SK. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells Am.J.Physiol.. 267: F271-F280. DOI: 10.1152/Ajprenal.1994.267.2.F271  0.406
1993 Santos OFP, Moura LA, Rosen EM, Nigam SK. Modulation of HGF-induced tubulogenesis and branching by multiple phosphorylation mechanisms Developmental Biology. 159: 535-548. PMID 8405677 DOI: 10.1006/Dbio.1993.1262  0.375
1993 Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ. Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. The Biochemical Journal. 511-5. PMID 8373365 DOI: 10.1042/Bj2940511  0.621
1993 Santos OFP, Nigam SK. HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-β Developmental Biology. 160: 293-302. PMID 8253265 DOI: 10.1006/Dbio.1993.1308  0.354
1993 Rauchman MI, Nigam SK, Delpire E, Gullans SR. An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse. The American Journal of Physiology. 265: F416-24. PMID 8214101 DOI: 10.1152/Ajprenal.1993.265.3.F416  0.354
1991 Nigam SK, Denisenko N, Rodriguez-Boulan E, Citi S. The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells Biochemical and Biophysical Research Communications. 181: 548-553. PMID 1755836 DOI: 10.1016/0006-291X(91)91224-Z  0.355
1987 Reeves WH, Nigam SK, Blobel G. Human autoantibodies reactive with the signal-recognition particle. Proceedings of the National Academy of Sciences of the United States of America. 83: 9507-11. PMID 2432596 DOI: 10.1073/Pnas.83.24.9507  0.487
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