Year |
Citation |
Score |
2022 |
Whisenant TC, Nigam SK. Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma. Cancers. 14. PMID 36230695 DOI: 10.3390/cancers14194772 |
0.319 |
|
2021 |
Granados JC, Nigam AK, Bush KT, Jamshidi N, Nigam SK. A key role for the transporter OAT1 in systemic lipid metabolism. The Journal of Biological Chemistry. 100603. PMID 33785360 DOI: 10.1016/j.jbc.2021.100603 |
0.601 |
|
2021 |
Granados JC, Richelle A, Gutierrez JM, Zhang P, Zhang X, Bhatnagar V, Lewis NE, Nigam SK. \Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3. The Journal of Biological Chemistry. 100575. PMID 33757768 DOI: 10.1016/j.jbc.2021.100575 |
0.31 |
|
2021 |
Torres AM, Dnyanmote AV, Granados JC, Nigam SK. Renal and non-renal response of ABC and SLC transporters in chronic kidney disease. Expert Opinion On Drug Metabolism & Toxicology. PMID 33749483 DOI: 10.1080/17425255.2021.1899159 |
0.306 |
|
2020 |
Bush KT, Singh P, Nigam SK. Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease. Jci Insight. 5. PMID 32271169 DOI: 10.1172/Jci.Insight.133817 |
0.684 |
|
2020 |
Engelhart DC, Azad P, Ali S, Granados JC, Haddad GG, Nigam SK. SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. International Journal of Molecular Sciences. 21. PMID 32183456 DOI: 10.3390/Ijms21062002 |
0.406 |
|
2020 |
Engelhart DC, Granados JC, Shi D, Saier Jr MH, Baker ME, Abagyan R, Nigam SK. Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs. International Journal of Molecular Sciences. 21. PMID 32150922 DOI: 10.3390/Ijms21051791 |
0.397 |
|
2020 |
Nigam SK, Bush KT, Bhatnagar V, Poloyac SM, Momper JD. The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology. Clinical Pharmacology and Therapeutics. PMID 32119114 DOI: 10.1002/Cpt.1818 |
0.67 |
|
2020 |
Nigam AK, Li JG, Lall K, Shi D, Bush KT, Bhatnagar V, Abagyan R, Nigam SK. Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning. The Journal of Biological Chemistry. PMID 31896576 DOI: 10.1074/Jbc.Ra119.010729 |
0.658 |
|
2019 |
Rosenthal SB, Bush KT, Nigam SK. A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis. Scientific Reports. 9: 11879. PMID 31417100 DOI: 10.1038/S41598-019-47798-X |
0.667 |
|
2019 |
Momper JD, Yang J, Gockenbach M, Vaida F, Nigam SK. Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 30885911 DOI: 10.2215/Cjn.10350818 |
0.404 |
|
2019 |
Nigam SK, Bush KT. Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling. Nature Reviews. Nephrology. PMID 30728454 DOI: 10.1038/S41581-019-0111-1 |
0.65 |
|
2018 |
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P. Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development. American Journal of Medical Genetics. Part A. PMID 30422383 DOI: 10.1002/Ajmg.A.40481 |
0.647 |
|
2018 |
Paquette A, Baloni P, Holloman A, Nigam S, Bammler T, Mao Q, Price ND. Temporal Transcriptomic Analysis of Metabolic Genes in Maternal Organs and Placenta During Murine Pregnancy. Biology of Reproduction. PMID 29939228 DOI: 10.1093/Biolre/Ioy148 |
0.326 |
|
2018 |
Nigam SK, Bhatnagar V. The systems biology of uric acid transporters: the role of remote sensing and signaling. Current Opinion in Nephrology and Hypertension. 27: 305-313. PMID 29847376 DOI: 10.1097/Mnh.0000000000000427 |
0.359 |
|
2018 |
Momper JD, Nigam SK. Developmental regulation of kidney and liver SLC and ABC drug transporters and drug metabolizing enzymes: the role of remote organ communication. Expert Opinion On Drug Metabolism & Toxicology. PMID 29746174 DOI: 10.1080/17425255.2018.1473376 |
0.418 |
|
2018 |
Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolić I, Vallon V. The organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin. American Journal of Physiology. Renal Physiology. PMID 29412698 DOI: 10.1152/Ajprenal.00503.2017 |
0.375 |
|
2018 |
Nigam SK. The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease. Annual Review of Pharmacology and Toxicology. 58: 663-687. PMID 29309257 DOI: 10.1146/Annurev-Pharmtox-010617-052713 |
0.406 |
|
2017 |
Bush KT, Wu W, Lun C, Nigam SK. The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis. The Journal of Biological Chemistry. PMID 28765282 DOI: 10.1074/Jbc.M117.796516 |
0.674 |
|
2017 |
Wu W, Bush KT, Nigam SK. Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes. Scientific Reports. 7: 4939. PMID 28694431 DOI: 10.1038/S41598-017-04949-2 |
0.674 |
|
2016 |
Liu HC, Goldenberg A, Chen Y, Lun C, Wu W, Bush KT, Balac N, Rodriguez P, Abagyan R, Nigam SK. Analysis of Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach. The Journal of Pharmacology and Experimental Therapeutics. PMID 27488918 DOI: 10.1124/Jpet.116.232660 |
0.63 |
|
2016 |
Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK. Construction and Evaluation of an Organic Anion Transporter 1 (OAT1)-Centered Metabolic Network. The Journal of Biological Chemistry. PMID 27440044 DOI: 10.1074/Jbc.M116.745216 |
0.67 |
|
2016 |
Bhatnagar V, Richard EL, Wu W, Nievergelt CM, Lipkowitz MS, Jeff J, Maihofer AX, Nigam SK. Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling. Clinical Kidney Journal. 9: 444-453. PMID 27274832 DOI: 10.1093/Ckj/Sfw010 |
0.414 |
|
2016 |
He X, Garza D, Nigam SK, Chang G. Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2. Plos One. 11: e0152969. PMID 27046168 DOI: 10.1371/Journal.Pone.0152969 |
0.378 |
|
2016 |
Martovetsky G, Bush KT, Nigam SK. Transcription factor-mediated regulation of kidney versus liver specification of Slc and Abc drug transporters, tight junction molecules and signature biomarkers. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27044799 DOI: 10.1124/Dmd.115.068254 |
0.696 |
|
2015 |
Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 4. PMID 26554899 DOI: 10.7554/Elife.08413 |
0.617 |
|
2015 |
Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Wu W, Nigam SK. Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. Plos One. 10: e0140569. PMID 26536134 DOI: 10.1371/Journal.Pone.0140569 |
0.648 |
|
2015 |
Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters. Clinical Journal of the American Society of Nephrology : Cjasn. 10: 2039-49. PMID 26490509 DOI: 10.2215/Cjn.02440314 |
0.68 |
|
2015 |
Wu W, Bush KT, Liu HC, Zhu C, Abagyan R, Nigam SK. Shared Ligands between Organic Anion Transporters (Oat1 and Oat6) and Odorant Receptors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26358290 DOI: 10.1124/Dmd.115.065250 |
0.645 |
|
2015 |
Eraly SA, Liu HC, Jamshidi N, Nigam SK. Transcriptome-based reconstructions from the murine knockout suggest involvement of the urate transporter, URAT1 (slc22a12), in novel metabolic pathways. Biochemistry and Biophysics Reports. 3: 51-61. PMID 26251846 DOI: 10.1016/J.Bbrep.2015.07.012 |
0.407 |
|
2015 |
Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clinical Pharmacology and Therapeutics. 98: 266-87. PMID 26088472 DOI: 10.1002/Cpt.176 |
0.337 |
|
2015 |
Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1859-68. PMID 25630970 DOI: 10.1096/Fj.14-257808 |
0.74 |
|
2015 |
Nigam SK, Bush KT, Martovetsky G, Ahn SY, Liu HC, Richard E, Bhatnagar V, Wu W. The organic anion transporter (OAT) family: a systems biology perspective. Physiological Reviews. 95: 83-123. PMID 25540139 DOI: 10.1152/Physrev.00025.2013 |
0.683 |
|
2015 |
Nigam SK. What do drug transporters really do? Nature Reviews. Drug Discovery. 14: 29-44. PMID 25475361 DOI: 10.1038/Nrd4461 |
0.346 |
|
2015 |
Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Author response: Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells Elife. DOI: 10.7554/Elife.08413.029 |
0.589 |
|
2014 |
Martovetsky G, Nigam SK. Cellular and developmental strategies aimed at kidney tissue engineering. Nephron. Experimental Nephrology. 126: 101. PMID 24854650 DOI: 10.1159/000360680 |
0.35 |
|
2014 |
Bush KT, Martovetsky G, Nigam SK. Relevance of ureteric bud development and branching to tissue engineering, regeneration and repair in acute and chronic kidney disease. Current Opinion in Organ Transplantation. 19: 153-61. PMID 24503495 DOI: 10.1097/Mot.0000000000000053 |
0.661 |
|
2014 |
Nigam SK, Bush KT. Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis. Pediatric Nephrology (Berlin, Germany). 29: 727-35. PMID 24488503 DOI: 10.1007/S00467-013-2725-Z |
0.67 |
|
2014 |
Bush KT, Nagle M, Truong DM, Bhatnagar V, Kaler G, Eraly SA, Wu W, Nigam SK. Organic Anion Transporters Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 25-41. DOI: 10.1002/9781118705308.ch3 |
0.599 |
|
2013 |
Nigam SK. Concise review: can the intrinsic power of branching morphogenesis be used for engineering epithelial tissues and organs? Stem Cells Translational Medicine. 2: 993-1000. PMID 24191267 DOI: 10.5966/Sctm.2013-0076 |
0.364 |
|
2013 |
Tee JB, Choi Y, Dnyanmote A, Decambre M, Ito C, Bush KT, Nigam SK. GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling. Biology Open. 2: 952-9. PMID 24143282 DOI: 10.1242/Bio.20135595 |
0.763 |
|
2013 |
Martovetsky G, Tee JB, Nigam SK. Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters. Molecular Pharmacology. 84: 808-23. PMID 24038112 DOI: 10.1124/Mol.113.088229 |
0.457 |
|
2013 |
Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, ... ... Nigam SK, et al. Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. Journal of the American Society of Nephrology : Jasn. 24: 1901-12. PMID 23949796 DOI: 10.1681/Asn.2013020126 |
0.322 |
|
2013 |
Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1825-34. PMID 23920220 DOI: 10.1124/Dmd.113.052647 |
0.664 |
|
2013 |
Nigam SK, Bhatnagar V. How much do we know about drug handling by SLC and ABC drug transporters in children? Clinical Pharmacology and Therapeutics. 94: 27-29. PMID 23778708 DOI: 10.1038/Clpt.2013.82 |
0.33 |
|
2013 |
Nagle MA, Wu W, Eraly SA, Nigam SK. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue. Neuroscience Letters. 534: 133-8. PMID 23196129 DOI: 10.1016/J.Neulet.2012.11.027 |
0.405 |
|
2013 |
Bush KT, Sakurai H, Nigam SK. Molecular and Cellular Mechanisms of Kidney Development Seldin and Geibisch's the Kidney. 1: 859-890. DOI: 10.1016/B978-0-12-381462-3.00025-2 |
0.609 |
|
2012 |
Bush KT, Crawford BE, Garner OB, Nigam KB, Esko JD, Nigam SK. N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland. The Journal of Biological Chemistry. 287: 42064-70. PMID 23060443 DOI: 10.1074/Jbc.M112.423327 |
0.628 |
|
2012 |
Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule. Plos One. 7: e40796. PMID 22808265 DOI: 10.1371/Journal.Pone.0040796 |
0.826 |
|
2012 |
Zhang X, Bush KT, Nigam SK. In vitro culture of embryonic kidney rudiments and isolated ureteric buds. Methods in Molecular Biology (Clifton, N.J.). 886: 13-21. PMID 22639247 DOI: 10.1007/978-1-61779-851-1_2 |
0.624 |
|
2012 |
Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. American Journal of Physiology. Renal Physiology. 302: F1293-9. PMID 22338083 DOI: 10.1152/Ajprenal.00013.2012 |
0.393 |
|
2012 |
Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Developmental Biology. 364: 11-21. PMID 22290330 DOI: 10.1016/J.Ydbio.2012.01.014 |
0.81 |
|
2011 |
Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK. Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. The Journal of Biological Chemistry. 286: 31522-31. PMID 21757732 DOI: 10.1074/Jbc.M111.272534 |
0.793 |
|
2011 |
Torres AM, Dnyanmote AV, Bush KT, Wu W, Nigam SK. Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury. The Journal of Biological Chemistry. 286: 26391-5. PMID 21652719 DOI: 10.1074/Jbc.M111.249292 |
0.653 |
|
2011 |
Shah MM, Sakurai H, Gallegos TF, Sweeney DE, Bush KT, Esko JD, Nigam SK. Growth factor-dependent branching of the ureteric bud is modulated by selective 6-O sulfation of heparan sulfate. Developmental Biology. 356: 19-27. PMID 21600196 DOI: 10.1016/J.Ydbio.2011.05.004 |
0.792 |
|
2011 |
Garner OB, Bush KT, Nigam KB, Yamaguchi Y, Xu D, Esko JD, Nigam SK. Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Developmental Biology. 355: 394-403. PMID 21586278 DOI: 10.1016/J.Ydbio.2011.04.035 |
0.683 |
|
2011 |
Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK. Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1). Bioorganic & Medicinal Chemistry. 19: 3320-40. PMID 21571536 DOI: 10.1016/J.Bmc.2011.04.045 |
0.367 |
|
2011 |
Tsigelny IF, Kovalskyy D, Kouznetsova VL, Balinskyi O, Sharikov Y, Bhatnagar V, Nigam SK. Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport. Cell Biochemistry and Biophysics. 61: 251-9. PMID 21499753 DOI: 10.1007/S12013-011-9191-7 |
0.378 |
|
2011 |
Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Molecular Pharmacology. 80: 147-54. PMID 21493727 DOI: 10.1124/Mol.110.070680 |
0.788 |
|
2011 |
Wikoff WR, Nagle MA, Kouznetsova VL, Tsigelny IF, Nigam SK. Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). Journal of Proteome Research. 10: 2842-51. PMID 21476605 DOI: 10.1021/Pr200093W |
0.39 |
|
2011 |
Wu W, Dnyanmote AV, Nigam SK. Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis. Molecular Pharmacology. 79: 795-805. PMID 21325265 DOI: 10.1124/Mol.110.070607 |
0.4 |
|
2011 |
Sweeney DE, Gallegos TF, Dnyanmote AV, Zhang X, Nigam SK. Branching morphogenesis: from individual molecules to a systems biology approach: commentary on "Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney" by Perälä et al. Differentiation; Research in Biological Diversity. 81: 79-80. PMID 21168258 DOI: 10.1016/J.Diff.2010.11.004 |
0.749 |
|
2011 |
Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, Nigam SK. Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling. The Journal of Biological Chemistry. 286: 243-51. PMID 20921221 DOI: 10.1074/Jbc.M110.139949 |
0.383 |
|
2010 |
Tee JB, Choi Y, Shah MM, Dnyanmote A, Sweeney DE, Gallegos TF, Johkura K, Ito C, Bush KT, Nigam SK. Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct. Developmental Biology. 347: 337-47. PMID 20816800 DOI: 10.1016/J.Ydbio.2010.08.029 |
0.796 |
|
2010 |
Crawford BE, Garner OB, Bishop JR, Zhang DY, Bush KT, Nigam SK, Esko JD. Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice. Plos One. 5: e10691. PMID 20502530 DOI: 10.1371/Journal.Pone.0010691 |
0.655 |
|
2010 |
Rosines E, Johkura K, Zhang X, Schmidt HJ, Decambre M, Bush KT, Nigam SK. Constructing kidney-like tissues from cells based on programs for organ development: toward a method of in vitro tissue engineering of the kidney. Tissue Engineering. Part A. 16: 2441-55. PMID 20214453 DOI: 10.1089/Ten.Tea.2009.0548 |
0.677 |
|
2010 |
Shah MM, Sakurai H, Sweeney DE, Gallegos TF, Bush KT, Esko JD, Nigam SK. Hs2st mediated kidney mesenchyme induction regulates early ureteric bud branching. Developmental Biology. 339: 354-65. PMID 20059993 DOI: 10.1016/J.Ydbio.2009.12.033 |
0.808 |
|
2010 |
Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK. The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects (American Journal Physiology-Renal Physiology (2009) 297, (F1330-F1341)) American Journal of Physiology - Renal Physiology. 298: F1285. DOI: 10.1152/ajprenal.zh2-5897-corr.2010 |
0.738 |
|
2009 |
Choi Y, Tee JB, Gallegos TF, Shah MM, Oishi H, Sakurai H, Kitamura S, Wu W, Bush KT, Nigam SK. Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct. Development (Cambridge, England). 136: 4213-24. PMID 19934016 DOI: 10.1242/Dev.037580 |
0.793 |
|
2009 |
Ahn SY, Eraly SA, Tsigelny I, Nigam SK. Interaction of organic cations with organic anion transporters. The Journal of Biological Chemistry. 284: 31422-30. PMID 19737926 DOI: 10.1074/Jbc.M109.024489 |
0.355 |
|
2009 |
Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK. The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects. American Journal of Physiology. Renal Physiology. 297: F1330-41. PMID 19726549 DOI: 10.1152/Ajprenal.00125.2009 |
0.802 |
|
2009 |
Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nature Medicine. 15: 1046-54. PMID 19718039 DOI: 10.1038/Nm.2010 |
0.394 |
|
2009 |
Ahn SY, Nigam SK. Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Molecular Pharmacology. 76: 481-90. PMID 19515966 DOI: 10.1124/Mol.109.056564 |
0.415 |
|
2009 |
Wu W, Kitamura S, Truong DM, Rieg T, Vallon V, Sakurai H, Bush KT, Vera DR, Ross RS, Nigam SK. Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. American Journal of Physiology. Renal Physiology. 297: F210-7. PMID 19439520 DOI: 10.1152/Ajprenal.90260.2008 |
0.667 |
|
2009 |
Wu W, Baker ME, Eraly SA, Bush KT, Nigam SK. Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiological Genomics. 38: 116-24. PMID 19417012 DOI: 10.1152/Physiolgenomics.90309.2008 |
0.65 |
|
2009 |
Nigam SK, Shah MM. How does the ureteric bud branch? Journal of the American Society of Nephrology : Jasn. 20: 1465-9. PMID 19056872 DOI: 10.1681/Asn.2008020132 |
0.411 |
|
2008 |
Nigam SK, Wu W, Bush KT. Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology. Organogenesis. 4: 137-43. PMID 19279725 DOI: 10.4161/Org.4.3.6498 |
0.661 |
|
2008 |
Tsigelny IF, Kouznetsova VL, Sweeney DE, Wu W, Bush KT, Nigam SK. Analysis of metagene portraits reveals distinct transitions during kidney organogenesis. Science Signaling. 1: ra16. PMID 19066399 DOI: 10.1126/Scisignal.1163630 |
0.646 |
|
2008 |
Tsigelny IF, Greenberg J, Kouznetsova V, Nigam SK. Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function. Journal of Bioinformatics and Computational Biology. 6: 885-904. PMID 18942157 DOI: 10.1142/S0219720008003801 |
0.346 |
|
2008 |
Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. Journal of the American Society of Nephrology : Jasn. 19: 1732-40. PMID 18508962 DOI: 10.1681/Asn.2008020180 |
0.37 |
|
2008 |
Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiological Genomics. 33: 180-92. PMID 18270321 DOI: 10.1152/Physiolgenomics.00207.2007 |
0.406 |
|
2008 |
Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK. Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. American Journal of Physiology. Renal Physiology. 294: F867-73. PMID 18216144 DOI: 10.1152/Ajprenal.00528.2007 |
0.436 |
|
2008 |
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. The Journal of Biological Chemistry. 283: 8654-63. PMID 18174163 DOI: 10.1074/Jbc.M708615200 |
0.393 |
|
2007 |
Rosines E, Sampogna RV, Johkura K, Vaughn DA, Choi Y, Sakurai H, Shah MM, Nigam SK. Staged in vitro reconstitution and implantation of engineered rat kidney tissue. Proceedings of the National Academy of Sciences of the United States of America. 104: 20938-43. PMID 18087037 DOI: 10.1073/Pnas.0710428105 |
0.661 |
|
2007 |
Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK. Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct. Journal of the American Society of Nephrology : Jasn. 18: 3147-55. PMID 18003772 DOI: 10.1681/Asn.2007060642 |
0.663 |
|
2007 |
Rosines E, Schmidt HJ, Nigam SK. The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissues. Biomaterials. 28: 4806-17. PMID 17706761 DOI: 10.1016/J.Biomaterials.2007.07.034 |
0.404 |
|
2007 |
Nigam SK, Bush KT, Bhatnagar V. Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues. Nature Clinical Practice. Nephrology. 3: 443-8. PMID 17653123 DOI: 10.1038/Ncpneph0558 |
0.679 |
|
2007 |
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of Biological Chemistry. 282: 23841-53. PMID 17553798 DOI: 10.1074/Jbc.M703467200 |
0.367 |
|
2007 |
Monte JC, Sakurai H, Bush KT, Nigam SK. The developmental nephrome: systems biology in the developing kidney. Current Opinion in Nephrology and Hypertension. 16: 3-9. PMID 17143064 DOI: 10.1097/Mnh.0B013E3280118A5A |
0.673 |
|
2007 |
Sakurai H, Bush KT, Kitamura S, Nigam SK. Differential regulation of tip and stalk of the branching ureteric bud The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A141-B |
0.63 |
|
2006 |
Meyer TN, Schwesinger C, Sampogna RV, Vaughn DA, Stuart RO, Steer DL, Bush KT, Nigam SK. Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development. Differentiation; Research in Biological Diversity. 74: 638-47. PMID 17177859 DOI: 10.1111/J.1432-0436.2006.00102.X |
0.69 |
|
2006 |
Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, Nigam SK. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochemical and Biophysical Research Communications. 351: 872-6. PMID 17094945 DOI: 10.1016/J.Bbrc.2006.10.136 |
0.335 |
|
2006 |
Bush KT, Vaughn DA, Li X, Rosenfeld MG, Rose DW, Mendoza SA, Nigam SK. Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system. Developmental Biology. 298: 571-84. PMID 16934795 DOI: 10.1016/J.Ydbio.2006.07.006 |
0.695 |
|
2006 |
Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). Journal of Human Genetics. 51: 575-80. PMID 16648942 DOI: 10.1007/S10038-006-0398-1 |
0.358 |
|
2006 |
Maeshima A, Vaughn DA, Choi Y, Nigam SK. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Developmental Biology. 295: 473-85. PMID 16643884 DOI: 10.1016/J.Ydbio.2006.03.011 |
0.665 |
|
2006 |
Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney International. 69: 837-45. PMID 16518343 DOI: 10.1038/Sj.Ki.5000170 |
0.698 |
|
2006 |
Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. The Journal of Biological Chemistry. 281: 5072-83. PMID 16354673 DOI: 10.1074/Jbc.M508050200 |
0.418 |
|
2006 |
Maeshima A, Sakurai H, Nigam SK. Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney. Journal of the American Society of Nephrology : Jasn. 17: 188-98. PMID 16338966 DOI: 10.1681/Asn.2005040370 |
0.421 |
|
2005 |
Sakurai H, Bush KT, Nigam SK. Heregulin induces glial cell line-derived neurotrophic growth factor-independent, non-branching growth and differentiation of ureteric bud epithelia. The Journal of Biological Chemistry. 280: 42181-7. PMID 16183643 DOI: 10.1074/Jbc.M507962200 |
0.68 |
|
2005 |
Xu G, Bhatnagar V, Wen G, Hamilton BA, Eraly SA, Nigam SK. Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)]. Kidney International. 68: 1491-9. PMID 16164626 DOI: 10.1111/J.1523-1755.2005.00612.X |
0.402 |
|
2004 |
Sampogna RV, Nigam SK. Implications of gene networks for understanding resilience and vulnerability in the kidney branching program. Physiology (Bethesda, Md.). 19: 339-47. PMID 15546851 DOI: 10.1152/Physiol.00025.2004 |
0.363 |
|
2004 |
Meyer TN, Schwesinger C, Bush KT, Stuart RO, Rose DW, Shah MM, Vaughn DA, Steer DL, Nigam SK. Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney. Developmental Biology. 275: 44-67. PMID 15464572 DOI: 10.1016/J.Ydbio.2004.07.022 |
0.7 |
|
2004 |
Monte JC, Nagle MA, Eraly SA, Nigam SK. Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa. Biochemical and Biophysical Research Communications. 323: 429-36. PMID 15369770 DOI: 10.1016/J.Bbrc.2004.08.112 |
0.406 |
|
2004 |
George SK, Meyer TN, Abdeen O, Bush KT, Nigam SK. Tunicamycin preserves intercellular junctions, cytoarchitecture, and cell-substratum interactions in ATP-depleted epithelial cells. Biochemical and Biophysical Research Communications. 322: 223-31. PMID 15313195 DOI: 10.1016/J.Bbrc.2004.07.097 |
0.644 |
|
2004 |
Steer DL, Shah MM, Bush KT, Stuart RO, Sampogna RV, Meyer TN, Schwesinger C, Bai X, Esko JD, Nigam SK. Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney. Developmental Biology. 272: 310-27. PMID 15282150 DOI: 10.1016/J.Ydbio.2004.04.029 |
0.709 |
|
2004 |
Tsigelny IF, Nigam SK. Complex dynamics of chaperone-protein interactions under cellular stress. Cell Biochemistry and Biophysics. 40: 263-76. PMID 15211027 DOI: 10.1385/Cbb:40:3:263 |
0.311 |
|
2004 |
Chen D, Roberts R, Pohl M, Nigam S, Kreidberg J, Wang Z, Heino J, Ivaska J, Coffa S, Harris RC, Pozzi A, Zent R. Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis American Journal of Physiology - Renal Physiology. 287: F602-F611. PMID 15187002 DOI: 10.1152/Ajprenal.00015.2004 |
0.342 |
|
2004 |
Sykes D, Sweet DH, Lowes S, Nigam SK, Pritchard JB, Miller DS. Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. American Journal of Physiology. Renal Physiology. 286: F972-8. PMID 15075193 DOI: 10.1152/Ajprenal.00356.2003 |
0.367 |
|
2004 |
Eraly SA, Monte JC, Nigam SK. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiological Genomics. 18: 12-24. PMID 15054140 DOI: 10.1152/Physiolgenomics.00014.2004 |
0.396 |
|
2004 |
Shah MM, Sampogna RV, Sakurai H, Bush KT, Nigam SK. Branching morphogenesis and kidney disease. Development (Cambridge, England). 131: 1449-62. PMID 15023929 DOI: 10.1242/Dev.01089 |
0.657 |
|
2004 |
Eraly SA, Bush KT, Sampogna RV, Bhatnagar V, Nigam SK. The molecular pharmacology of organic anion transporters: from DNA to FDA? Molecular Pharmacology. 65: 479-87. PMID 14978224 DOI: 10.1124/Mol.65.3.479 |
0.656 |
|
2004 |
Bush KT, Sakurai H, Steer DL, Leonard MO, Sampogna RV, Meyer TN, Schwesinger C, Qiao J, Nigam SK. TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud. Developmental Biology. 266: 285-98. PMID 14738877 DOI: 10.1016/J.Ydbio.2003.10.023 |
0.648 |
|
2004 |
Steer DL, Nigam SK. Developmental approaches to kidney tissue engineering. American Journal of Physiology. Renal Physiology. 286: F1-7. PMID 14656756 DOI: 10.1152/Ajprenal.00167.2003 |
0.383 |
|
2004 |
Li X, Ohgi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Erratum: Corrigendum: Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis Nature. 427: 265-265. DOI: 10.1038/Nature02283 |
0.601 |
|
2003 |
Nigam SK. From the ureteric bud to the penome. Kidney International. 64: 2320-2. PMID 14633158 DOI: 10.1046/J.1523-1755.2003.00397.X |
0.342 |
|
2003 |
Stuart RO, Bush KT, Nigam SK. Changes in gene expression patterns in the ureteric bud and metanephric mesenchyme in models of kidney development. Kidney International. 64: 1997-2008. PMID 14633122 DOI: 10.1046/J.1523-1755.2003.00383.X |
0.682 |
|
2003 |
Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 426: 247-54. PMID 14628042 DOI: 10.1038/Nature02083 |
0.648 |
|
2003 |
Eraly SA, Blantz RC, Bhatnagar V, Nigam SK. Novel aspects of renal organic anion transporters. Current Opinion in Nephrology and Hypertension. 12: 551-8. PMID 12920404 DOI: 10.1097/00041552-200309000-00011 |
0.407 |
|
2003 |
Keller SH, Nigam SK. Biochemical processing of E-cadherin under cellular stress. Biochemical and Biophysical Research Communications. 307: 215-23. PMID 12859942 DOI: 10.1016/S0006-291X(03)01143-4 |
0.333 |
|
2003 |
Li Z, Stuart RO, Eraly SA, Gittes G, Beier DR, Nigam SK. Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis. Biochemical and Biophysical Research Communications. 306: 623-8. PMID 12810064 DOI: 10.1016/S0006-291X(03)00875-1 |
0.408 |
|
2003 |
Eraly SA, Hamilton BA, Nigam SK. Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochemical and Biophysical Research Communications. 300: 333-42. PMID 12504088 DOI: 10.1016/S0006-291X(02)02853-X |
0.373 |
|
2002 |
Steer DL, Bush KT, Meyer TN, Schwesinger C, Nigam SK. A strategy for in vitro propagation of rat nephrons. Kidney International. 62: 1958-65. PMID 12427120 DOI: 10.1046/J.1523-1755.2002.00694.X |
0.593 |
|
2002 |
Eraly SA, Nigam SK. Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochemical and Biophysical Research Communications. 297: 1159-66. PMID 12372408 DOI: 10.1016/S0006-291X(02)02343-4 |
0.378 |
|
2002 |
Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. The Journal of Biological Chemistry. 277: 26934-43. PMID 12011098 DOI: 10.1074/Jbc.M203803200 |
0.409 |
|
2002 |
Pohl M, Bhatnagar V, Mendoza SA, Nigam SK. Toward an etiological classification of developmental disorders of the kidney and upper urinary tract. Kidney International. 61: 10-9. PMID 11786080 DOI: 10.1046/J.1523-1755.2002.00086.X |
0.326 |
|
2001 |
Zent R, Bush KT, Pohl ML, Quaranta V, Koshikawa N, Wang Z, Kreidberg JA, Sakurai H, Stuart RO, Nigám SK. Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development Developmental Biology. 238: 289-302. PMID 11784011 DOI: 10.1006/Dbio.2001.0391 |
0.641 |
|
2001 |
Qiao J, Bush KT, Steer DL, Stuart RO, Sakurai H, Wachsman W, Nigam SK. Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis Mechanisms of Development. 109: 123-135. PMID 11731227 DOI: 10.1016/S0925-4773(01)00592-5 |
0.653 |
|
2001 |
Stuart RO, Pavlova A, Beier D, Li Z, Krijanovski Y, Nigam SK. EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis. American Journal of Physiology. Renal Physiology. 281: F1148-56. PMID 11704567 DOI: 10.1152/Ajprenal.2001.281.6.F1148 |
0.399 |
|
2001 |
Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proceedings of the National Academy of Sciences of the United States of America. 98: 12509-14. PMID 11606725 DOI: 10.1073/Pnas.221205198 |
0.681 |
|
2001 |
Sakurai H, Bush KT, Nigam SK. Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis Development. 128: 3283-3293. PMID 11546745 |
0.308 |
|
2001 |
Sweet DH, Bush KT, Nigam SK. The organic anion transporter family: From physiology to ontogeny and the clinic American Journal of Physiology - Renal Physiology. 281: F197-F205. PMID 11457711 DOI: 10.1152/Ajprenal.2001.281.2.F197 |
0.659 |
|
2001 |
Saha C, Nigam SK, Denker BM. Expanding role of G proteins in tight junction regulation: Gα s stimulates TJ assembly Biochemical and Biophysical Research Communications. 285: 250-256. PMID 11444833 DOI: 10.1006/Bbrc.2001.5154 |
0.335 |
|
2001 |
Stuart RO, Bush KT, Nigam SK. Changes in global gene expression patterns during development and maturation of the rat kidney Proceedings of the National Academy of Sciences of the United States of America. 98: 5649-5654. PMID 11331749 DOI: 10.1073/Pnas.091110798 |
0.662 |
|
2001 |
Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Molecular and Cellular Biology. 21: 765-70. PMID 11154264 DOI: 10.1128/Mcb.21.3.765-770.2001 |
0.633 |
|
2001 |
Nigam SK, Bush KT. Folding and bioassembly of secretory proteins in health and disease Kidney International. 60: 397. DOI: 10.1046/J.1523-1755.2001.00821-3.X |
0.569 |
|
2000 |
Pohl M, Sakurai H, Bush KT, Nigam SK. Matrix metalloproteinases and their inhibitors regulate in vitro ureteric bud branching morphogenesis American Journal of Physiology - Renal Physiology. 279: F891-F900. PMID 11053050 DOI: 10.1152/Ajprenal.2000.279.5.F891 |
0.607 |
|
2000 |
Bush KT, Keller SH, Nigam SK. Genesis and reversal of the ischemic phenotype in epithelial cells Journal of Clinical Investigation. 106: 621-626. PMID 10974012 DOI: 10.1172/Jci10968 |
0.669 |
|
2000 |
Li Z, Stuart RO, Qiao J, Pavlova A, Bush KT, Pohl M, Sakurai H, Nigam SK. A role for timeless in epithelial morphogenesis during kidney development Proceedings of the National Academy of Sciences of the United States of America. 97: 10038-10043. PMID 10963667 DOI: 10.1073/Pnas.97.18.10038 |
0.714 |
|
2000 |
Pohl M, Sakurai H, Stuart RO, Nigam SK. Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells Developmental Biology. 224: 312-325. PMID 10926769 DOI: 10.1006/Dbio.2000.9783 |
0.361 |
|
2000 |
Nigam SK, Lieberthal W. Acute renal failure. III. The role of growth factors in the process of renal regeneration and repair American Journal of Physiology - Renal Physiology. 279: F3-F11. PMID 10894783 DOI: 10.1152/Ajprenal.2000.279.1.F3 |
0.36 |
|
2000 |
Pohl M, Stuart RO, Sakurai H, Nigam SK. Branching morphogenesis during kidney development Annual Review of Physiology. 62: 595-620. PMID 10845104 DOI: 10.1146/Annurev.Physiol.62.1.595 |
0.443 |
|
2000 |
Bush KT, Tsukamoto T, Nigam SK. Selective degradation of E-cadherin and dissolution of E-cadherin- catenin complexes in epithelial ischemia American Journal of Physiology - Renal Physiology. 278: F847-F852. PMID 10807598 DOI: 10.1152/Ajprenal.2000.278.5.F847 |
0.627 |
|
2000 |
Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK. Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. American Journal of Physiology. Renal Physiology. 278: F635-43. PMID 10751225 DOI: 10.1152/Ajprenal.2000.278.4.F635 |
0.447 |
|
2000 |
Lieberthal W, Nigam SK. Acute renal failure. II. Experimental models of acute renal failure: Imperfect but indispensable American Journal of Physiology - Renal Physiology. 278: F1-F12. PMID 10644651 DOI: 10.1152/Ajprenal.2000.278.1.F1 |
0.327 |
|
1999 |
Pavlova A, Stuart RO, Pohl M, Nigam SK. Evolution of gene expression patterns in a model of branching morphogenesis American Journal of Physiology - Renal Physiology. 277: F650-F663. PMID 10516290 DOI: 10.1152/Ajprenal.1999.277.4.F650 |
0.41 |
|
1999 |
Ye J, Tsukamoto T, Sun A, Nigam SK. A role for intracellular calcium in tight junction reassembly after ATP depletion-repletion American Journal of Physiology - Renal Physiology. 277: F524-F532. PMID 10516276 DOI: 10.1152/Ajprenal.1999.277.4.F524 |
0.305 |
|
1999 |
Tsukamoto T, Nigam SK. Cell-cell dissociation upon epithelial cell scattering requires a step mediated by the proteasome Journal of Biological Chemistry. 274: 24579-24584. PMID 10455122 DOI: 10.1074/Jbc.274.35.24579 |
0.324 |
|
1999 |
Bush KT, George SK, Zhang PL, Nigam SK. Pretreatment with inducers of ER molecular chaperones protects epithelial cells subjected to ATP depletion American Journal of Physiology - Renal Physiology. 277: F211-F218. PMID 10444575 DOI: 10.1152/Ajprenal.1999.277.2.F211 |
0.644 |
|
1999 |
Qiao J, Sakurai H, Nigam SK. Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney Proceedings of the National Academy of Sciences of the United States of America. 96: 7330-7335. PMID 10377414 DOI: 10.1073/Pnas.96.13.7330 |
0.433 |
|
1999 |
Tsukamoto T, Nigam SK. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins American Journal of Physiology - Renal Physiology. 276: F737-F750. PMID 10330056 DOI: 10.1152/Ajprenal.1999.276.5.F737 |
0.304 |
|
1999 |
O'Rourke DA, Sakurai H, Spokes K, Kjelsberg C, Takahashi M, Nigam S, Cantley L. Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells. The American Journal of Physiology. 276: F581-8. PMID 10198418 DOI: 10.1152/Ajprenal.1999.276.4.F581 |
0.343 |
|
1999 |
Bush KT, Nigam SK. Less degradation, more shock, please Gastroenterology. 116: 994-996. PMID 10092324 DOI: 10.1016/S0016-5085(99)70085-5 |
0.549 |
|
1998 |
Kuznetsov G, Nigam SK. Folding of secretory and membrane proteins New England Journal of Medicine. 339: 1688-1695. PMID 9834307 DOI: 10.1056/Nejm199812033392307 |
0.318 |
|
1998 |
Lieberthal W, Nigam SK. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury American Journal of Physiology - Renal Physiology. 275: F623-F631. PMID 9815122 DOI: 10.1152/Ajprenal.1998.275.5.F623 |
0.311 |
|
1998 |
Saha C, Nigam SK, Denker BM. Involvement of Gα(i2) in the maintenance and biogenesis of epithelial cell tight junctions Journal of Biological Chemistry. 273: 21629-21633. PMID 9705295 DOI: 10.1074/Jbc.273.34.21629 |
0.341 |
|
1998 |
Sakurai H, Nigam SK. In vitro branching tubulogenesis: Implications for developmental and cystic disorders, nephron number, renal repair, and nephron engineering Kidney International. 54: 14-26. PMID 9648059 DOI: 10.1046/J.1523-1755.1998.00969.X |
0.408 |
|
1998 |
Denker BM, Nigam SK. Molecular structure and assembly of the tight junction American Journal of Physiology - Renal Physiology. 274: F1-F9. PMID 9458817 DOI: 10.1152/Ajprenal.1998.274.1.F1 |
0.387 |
|
1997 |
Sakurai H, Tsukamoto T, Kjelsberg CA, Cantley LG, Nigam SK. EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney American Journal of Physiology - Renal Physiology. 273: F463-F472. PMID 9321921 DOI: 10.1152/Ajprenal.1997.273.3.F463 |
0.389 |
|
1997 |
Tsukamoto T, Nigam SK. Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly Journal of Biological Chemistry. 272: 16133-16139. PMID 9195909 DOI: 10.1074/Jbc.272.26.16133 |
0.334 |
|
1997 |
Sakurai H, Barros EJ, Tsukamoto T, Barasch J, Nigam SK. An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors Proceedings of the National Academy of Sciences of the United States of America. 94: 6279-6284. PMID 9177208 DOI: 10.1073/Pnas.94.12.6279 |
0.366 |
|
1997 |
Geng L, Segal Y, Pavlova A, Barros EJ, Löhning C, Lu W, Nigam SK, Frischauf AM, Reeders ST, Zhou J. Distribution and developmentally regulated expression of murine polycystin. The American Journal of Physiology. 272: F451-9. PMID 9140045 DOI: 10.1152/Ajprenal.1997.272.4.F451 |
0.409 |
|
1997 |
Kjelsberg C, Sakurai H, Spokes K, Birchmeier C, Drummond I, Nigam S, Cantley LG. Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands American Journal of Physiology-Renal Physiology. 272. PMID 9124399 DOI: 10.1152/Ajprenal.1997.272.2.F222 |
0.391 |
|
1997 |
Bush KT, Goldberg AL, Nigam SK. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance Journal of Biological Chemistry. 272: 9086-9092. PMID 9083035 DOI: 10.1074/Jbc.272.14.9086 |
0.614 |
|
1997 |
Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. The Journal of Biological Chemistry. 272: 6471-8. PMID 9045672 DOI: 10.1074/Jbc.272.10.6471 |
0.697 |
|
1997 |
Sakurai H, Nigam SK. Transforming growth factor-β selectively inhibits branching morphogenesis but not tubulogenesis American Journal of Physiology - Renal Physiology. 272: F139-F146. PMID 9039060 DOI: 10.1152/Ajprenal.1997.272.1.F139 |
0.329 |
|
1997 |
Kuznetsov G, Chen LB, Nigam SK. Multiple molecular chaperones complex with misfolded large oligomeric glycoproteins in the endoplasmic reticulum Journal of Biological Chemistry. 272: 3057-3063. PMID 9006956 DOI: 10.1074/Jbc.272.5.3057 |
0.307 |
|
1996 |
Kuznetsov G, Bush KT, Zhang PL, Nigam SK. Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia Proceedings of the National Academy of Sciences of the United States of America. 93: 8584-8589. PMID 8710914 DOI: 10.1073/Pnas.93.16.8584 |
0.648 |
|
1996 |
Stuart RO, Sun A, Bush KT, Nigam SK. Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores Journal of Biological Chemistry. 271: 13636-13641. PMID 8662885 DOI: 10.1074/Jbc.271.23.13636 |
0.629 |
|
1995 |
Stuart RO, Barros EJG, Ribeiro E, Nigam SK. Epithelial tubulogenesis through branching morphogenesis: Relevance to collecting system development Journal of the American Society of Nephrology. 6: 1151-1159. PMID 8589281 |
0.31 |
|
1995 |
Barros EJG, Santos OFP, Matsumoto K, Nakamura T, Nigam SK. Differential tubulogenic and branching morphogenetic activities of growth factors: Implications for epithelial tissue development Proceedings of the National Academy of Sciences of the United States of America. 92: 4412-4416. PMID 7753820 DOI: 10.1073/Pnas.92.10.4412 |
0.369 |
|
1995 |
Derman MP, Cunha MJ, Barros EJG, Nigam SK, Cantley LG. HGF-mediated chemotaxis and tubulogenesis require activation of the phosphatidylinositol 3-kinase American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268: F1211-F1217. PMID 7611461 DOI: 10.1152/Ajprenal.1995.268.6.F1211 |
0.356 |
|
1995 |
Stuart RO, Nigam SK. Regulated assembly of tight junctions by protein kinase C Proceedings of the National Academy of Sciences of the United States of America. 92: 6072-6076. PMID 7597083 DOI: 10.1073/Pnas.92.13.6072 |
0.325 |
|
1995 |
Stuart RO, Nigam SK. Development of the tubular nephron Seminars in Nephrology. 15: 315-326. PMID 7569411 |
0.323 |
|
1995 |
You G, Lee WS, Barros EJG, Kanai Y, Huo TL, Khawaja S, Wells RG, Nigam SK, Hediger MA. Molecular characteristics of Na+-coupled glucose transporters in adult and embryonic rat kidney Journal of Biological Chemistry. 270: 29365-29371. PMID 7493971 DOI: 10.1074/Jbc.270.49.29365 |
0.367 |
|
1995 |
Nigam S. Forefronts in Nephrology: The molecular basis of renal cystic disease Kidney International. 47: 717-718. DOI: 10.1038/Ki.1995.91 |
0.326 |
|
1994 |
Santos OFP, Barros EJG, Yang XM, Matsumoto K, Nakamura T, Park M, Nigam SK. Involvement of hepatocyte growth factor in kidney development Developmental Biology. 163: 525-529. PMID 8200486 DOI: 10.1006/Dbio.1994.1169 |
0.426 |
|
1994 |
Bush KT, Hendrickson BA, Nigam SK. Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum Biochemical Journal. 303: 705-708. PMID 7526846 DOI: 10.1042/Bj3030705 |
0.617 |
|
1994 |
Cantley LG, Barros EJG, Gandhi M, Rauchman M, Nigam SK. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells Am.J.Physiol.. 267: F271-F280. DOI: 10.1152/Ajprenal.1994.267.2.F271 |
0.406 |
|
1993 |
Santos OFP, Moura LA, Rosen EM, Nigam SK. Modulation of HGF-induced tubulogenesis and branching by multiple phosphorylation mechanisms Developmental Biology. 159: 535-548. PMID 8405677 DOI: 10.1006/Dbio.1993.1262 |
0.375 |
|
1993 |
Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ. Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. The Biochemical Journal. 511-5. PMID 8373365 DOI: 10.1042/Bj2940511 |
0.621 |
|
1993 |
Santos OFP, Nigam SK. HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-β Developmental Biology. 160: 293-302. PMID 8253265 DOI: 10.1006/Dbio.1993.1308 |
0.354 |
|
1993 |
Rauchman MI, Nigam SK, Delpire E, Gullans SR. An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse. The American Journal of Physiology. 265: F416-24. PMID 8214101 DOI: 10.1152/Ajprenal.1993.265.3.F416 |
0.354 |
|
1991 |
Nigam SK, Denisenko N, Rodriguez-Boulan E, Citi S. The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells Biochemical and Biophysical Research Communications. 181: 548-553. PMID 1755836 DOI: 10.1016/0006-291X(91)91224-Z |
0.355 |
|
1987 |
Reeves WH, Nigam SK, Blobel G. Human autoantibodies reactive with the signal-recognition particle. Proceedings of the National Academy of Sciences of the United States of America. 83: 9507-11. PMID 2432596 DOI: 10.1073/Pnas.83.24.9507 |
0.487 |
|
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