Xinbin Chen - Publications

Affiliations: 
Cell Biology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Cell Biology

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang Y, Feng X, Zhang J, Chen M, Huang E, Chen X. Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis. Oncogene. PMID 31332290 DOI: 10.1038/s41388-019-0876-5  0.36
2019 Mohibi S, Chen X, Zhang J. Cancer The 'RBP'eutics - RNA-Binding Proteins as Therapeutic Targets for Cancer. Pharmacology & Therapeutics. PMID 31302171 DOI: 10.1016/j.pharmthera.2019.07.001  0.36
2019 Zhang J, Sun W, Ren C, Kong X, Yan W, Chen X. A PolH transcript with a short 3'UTR enhances PolH expression and mediates cisplatin resistance. Cancer Research. PMID 31064846 DOI: 10.1158/0008-5472.CAN-18-3928  0.36
2018 Lucchesi CA, Zhang J, Ma B, Chen M, Chen X. Disruption of the Rbm38-eIF4E complex with a synthetic peptide Pep8 increases p53 expression. Cancer Research. PMID 30591552 DOI: 10.1158/0008-5472.CAN-18-2209  0.36
2018 Zhang Y, Feng X, Sun W, Zhang J, Chen X. Serine-195 phosphorylation in the RNA-binding protein Rbm38 increases p63 expression by modulating Rbm38's interaction with the Ago2-miR203 complex. The Journal of Biological Chemistry. PMID 30567739 DOI: 10.1074/jbc.RA118.005779  0.36
2018 Zhang J, Chen X. p53 Tumor Suppressor and Iron Homeostasis. The Febs Journal. PMID 30133149 DOI: 10.1111/febs.14638  0.36
2018 Ming X, Bao C, Hong T, Yang Y, Chen X, Jung YS, Qian Y. Clusterin, a novel DEC1 target, modulates DNA damage-mediated cell death. Molecular Cancer Research : McR. PMID 30002194 DOI: 10.1158/1541-7786.MCR-18-0070  1
2018 Jiang Y, Xu E, Zhang J, Chen M, Flores E, Chen X. The Rbm38-p63 feedback loop is critical for tumor suppression and longevity. Oncogene. PMID 29520104 DOI: 10.1038/s41388-018-0176-5  0.36
2018 Zhang M, Zhang Y, Xu E, Mohibi S, de Anda DM, Jiang Y, Zhang J, Chen X. Rbm24, a target of p53, is necessary for proper expression of p53 and heart development. Cell Death and Differentiation. PMID 29358667 DOI: 10.1038/s41418-017-0029-8  0.36
2018 Zhang J, Xu E, Ren C, Yang HJ, Zhang Y, Sun W, Kong X, Zhang W, Chen M, Huang EC, Chen X. Genetic ablation of Rbm38 promotes lymphomagenesis in the context of mutant p53 by downregulating PTEN. Cancer Research. PMID 29330147 DOI: 10.1158/0008-5472.CAN-17-2457  0.36
2017 Yan W, Zhang Y, Chen X. TAp63γ and ΔNp63γ are regulated by RBM38 via mRNA stability and have an opposing function in growth suppression. Oncotarget. 8: 78327-78339. PMID 29108232 DOI: 10.18632/oncotarget.18463  0.32
2017 Yang HJ, Zhang J, Yan W, Cho SJ, Lucchesi C, Chen M, Huang EC, Scoumanne A, Zhang W, Chen X. Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 114: 11500-11505. PMID 29073078 DOI: 10.1073/pnas.1711814114  0.36
2017 Zhang Y, Qian Y, Zhang J, Yan W, Jung YS, Chen M, Huang E, Lloyd K, Duan Y, Wang J, Liu G, Chen X. Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2. Genes & Development. PMID 28747430 DOI: 10.1101/gad.299388.117  1
2017 Yan W, Zhang Y, Chen X. TAp63γ and ΔNp63γ are regulated by RBM38 via mRNA stability and have an opposing function in growth suppression. Oncotarget. PMID 28645112 DOI: 10.18632/oncotarget.18463  0.32
2016 Lucchesi C, Zhang J, Chen X. Modulation of the p53 family network by RNA-binding proteins. Translational Cancer Research. 5: 676-684. PMID 28794999 DOI: 10.21037/tcr.2016.08.30  0.36
2016 Zhang M, Zhang J, Yan W, Chen X. p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability. Oncotarget. PMID 27825141 DOI: 10.18632/oncotarget.13126  0.36
2016 Wang J, Wang H, Wang LY, Cai D, Duan Z, Zhang Y, Chen P, Zou JX, Xu J, Chen X, Kung HJ, Chen HW. Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy. Cell Death and Differentiation. PMID 27612013 DOI: 10.1038/cdd.2016.92  0.32
2016 Zhang J, Lucchesi C, Chen X. A New Function for p53 Tetramerization Domain in Cell Fate Control. Cell Cycle (Georgetown, Tex.). 0. PMID 27355441 DOI: 10.1080/15384101.2016.1204868  0.36
2016 Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi AM, Wang J, Chen X, Dong H, Siu K, Winkler JD, Crew AP, Crews CM, Coleman KG. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274052 DOI: 10.1073/pnas.1521738113  1
2016 Xu T, Ni D, Chen X, Wu F, Ge P, Lu W, Hu H, Zhu Z, Chen W. Self-floating graphitic carbon nitride/zinc phthalocyanine nanofibers for photocatalytic degradation of contaminants. Journal of Hazardous Materials. 317: 17-26. PMID 27239724 DOI: 10.1016/j.jhazmat.2016.05.043  0.36
2016 Chen J, Li W, Jin E, He Q, Yan W, Yang H, Gong S, Guo Y, Fu S, Chen X, Ye S, Qian Y. The antiviral activity of arctigenin in traditional Chinese medicine on porcine circovirus type 2. Research in Veterinary Science. 106: 159-64. PMID 27234554 DOI: 10.1016/j.rvsc.2015.10.012  1
2016 Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH, Yang WN, Qu QM. The p38 mitogen-activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain. The International Journal of Biochemistry & Cell Biology. PMID 27163530 DOI: 10.1016/j.biocel.2016.04.019  0.36
2016 Yi X, Sun J, Li L, Wei Q, Qian Y, Chen X, Ma L. 1,25-Dihydroxyvitamin D3 Deficiency is Involved in the Pathogenesis of Diabetic Retinopathy in the Uygur Population of China. Iubmb Life. PMID 27080220 DOI: 10.1002/iub.1501  1
2016 Qian Y, Zhang Y, Zhong P, Peng K, Xu Z, Chen X, Lu K, Chen G, Li X, Liang G. Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity. Journal of Cellular and Molecular Medicine. PMID 27019072 DOI: 10.1111/jcmm.12832  1
2016 Chen X, Du Y, Lin X, Qian Y, Zhou T, Huang Z. CD4+CD25+ regulatory T cells in tumor immunity. International Immunopharmacology. 34: 244-249. PMID 26994448 DOI: 10.1016/j.intimp.2016.03.009  1
2016 Qian J, Qian Y, Wang J, Gu B, Pei D, He S, Zhu F, Røe OD, Xu J, Liu L, Gu Y, Guo R, Yin Y, Shu Y, Chen X. A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy. Drug Design, Development and Therapy. 10: 241-58. PMID 26966350 DOI: 10.2147/DDDT.S88743  1
2016 Xu C, Liu R, Zhang Q, Chen X, Qian Y, Fang W. The diversification of evolutionarily conserved MAPK cascades correlates with the evolution of fungal species and development of lifestyles. Genome Biology and Evolution. PMID 26957028 DOI: 10.1093/gbe/evw051  1
2016 Yan W, Scoumanne A, Jung YS, Xu E, Zhang J, Zhang Y, Ren C, Sun P, Chen X. Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation. Genes & Development. PMID 26915821 DOI: 10.1101/gad.271890.115  1
2016 Ren C, Zhang J, Yan W, Zhang Y, Chen X. RNA-Binding Protein PCBP2 regulates p73 expression and p73-dependent antioxidant defense. The Journal of Biological Chemistry. PMID 26907686 DOI: 10.1074/jbc.M115.712125  1
2016 Cheng C, Zhou Y, Li H, Xiong T, Li S, Bi Y, Kong P, Wang F, Cui H, Li Y, Fang X, Yan T, Li Y, Wang J, Yang B, ... ... Chen X, et al. Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma. American Journal of Human Genetics. PMID 26833333 DOI: 10.1016/j.ajhg.2015.12.013  1
2016 Du H, Zhu H, Chen X, Dong W, Lu W, Luo W, Jiang M, Liu T, Ding Y. Study on CaO-promoted Co/AC catalysts for synthesis of higher alcohols from syngas Fuel. 182: 42-49. DOI: 10.1016/j.fuel.2016.05.089  0.32
2016 Chen X, Tianfield H, Du W, Liu G. Biogeography-based optimization with covariance matrix based migration Applied Soft Computing Journal. 45: 71-85. DOI: 10.1016/j.asoc.2016.04.022  0.32
2015 Chen X, Xu C, Qian Y, Liu R, Zhang Q, Zeng G, Zhang X, Zhao H, Fang W. MAPK cascade-mediated regulation of pathogenicity, conidiation and tolerance to abiotic stresses in the entomopathogenic fungus Metarhizium robertsii. Environmental Microbiology. PMID 26714892 DOI: 10.1111/1462-2920.13198  1
2015 Lv Y, Qian Y, Fu L, Chen X, Zhong H, Wei X. Hydroxysafflor Yellow A Exerts Neuroprotective Effects In Cerebral Ischemia Reperfusion-injured Mice By Suppressing The Innate Immune TLR4-inducing Pathway. European Journal of Pharmacology. PMID 26607471 DOI: 10.1016/j.ejphar.2015.11.036  1
2015 Song B, Cui H, Li Y, Cheng C, Yang B, Wang F, Kong P, Li H, Zhang L, Jia Z, Bi Y, Wang J, Zhou Y, Liu J, Wang J, ... ... Chen X, et al. Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China. Oncotarget. PMID 26528858 DOI: 10.18632/oncotarget.6120  1
2015 Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson DL. Companion animals: Translational scientist's new best friends. Science Translational Medicine. 7: 308ps21. PMID 26446953 DOI: 10.1126/scitranslmed.aaa9116  1
2015 Granchi C, Qian Y, Lee HY, Paterni I, Pasero C, Iegre J, Carlson KE, Tuccinardi T, Chen X, Katzenellenbogen JA, Hergenrother PJ, Minutolo F. Salicylketoximes That Target Glucose Transporter 1 Restrict Energy Supply to Lung Cancer Cells. Chemmedchem. PMID 26332543 DOI: 10.1002/cmdc.201500320  1
2015 Qian Y, Chen XN, Shi H, Xie J, Chen N. Refractory Abdominal Pain in a Hemodialysis Patient. Case Reports in Nephrology and Dialysis. 5: 145-51. PMID 26266246 DOI: 10.1159/000431084  1
2015 Hao L, Shi Y, Xiao R, Qian Y, Chen X. Study on sampled waveguide grating with anti-symmetric periodic structure. Optics Express. 23: 15784-91. PMID 26193557  1
2015 Tang J, Qian Y, Li H, Kopecky BJ, Ding D, Ou HC, DeCook R, Chen X, Sun Z, Kobel M, Bao J. Canertinib induces ototoxicity in three preclinical models. Hearing Research. 328: 59-66. PMID 26163095 DOI: 10.1016/j.heares.2015.07.002  1
2015 Zhang Y, Young A, Zhang J, Chen X. P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition. Oncotarget. 6: 13994-4004. PMID 26101856  0.36
2015 Liu X, Malki A, Cao Y, Li Y, Qian Y, Wang X, Chen X. Glucose- and Triglyceride-lowering Dietary Penta-O-galloyl-α-D-Glucose Reduces Expression of PPARγ and C/EBPα, Induces p21-Mediated G1 Phase Cell Cycle Arrest, and Inhibits Adipogenesis in 3T3-L1 Preadipocytes. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 123: 308-16. PMID 25988880 DOI: 10.1055/s-0035-1548789  1
2015 Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y, Tang Y, Weirauch MT, Chen X, Zhu W, Wang Y, Chen B, Qian Y, et al. MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis. Nature Communications. 6: 7096. PMID 25963922 DOI: 10.1038/ncomms8096  1
2015 Zhao Y, Shen L, Chen X, Qian Y, Zhou Q, Wang Y, Li K, Liu M, Zhang S, Huang X. High expression of PKM2 as a poor prognosis indicator is associated with radiation resistance in cervical cancer. Histology and Histopathology. 11627. PMID 25936600 DOI: 10.14670/HH-11-627  1
2015 He F, Luo J, Zhang Z, Luo Z, Fan L, He Y, Wen J, Zhu D, Gao J, Wang Y, Qian Y, Zhou H, Chen X, Zhang W. The RGS2 (-391, C>G) genetic variation correlates to antihypertensive drug responses in Chinese patients with essential hypertension. Plos One. 10: e0121483. PMID 25849301 DOI: 10.1371/journal.pone.0121483  1
2015 Qian Y, Shi D, Qiu J, Zhu F, Qian J, He S, Shu Y, Yin Y, Chen X. ObRb downregulation increases breast cancer cell sensitivity to tamoxifen. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 25846733 DOI: 10.1007/s13277-015-3375-5  1
2015 Chen Z, Smith M, Du H, Guo Y, Clarke R, Zheng B, Collins R, Chen J, Qian Y, Wang X, Chen X, Tian X, Wang X, Peto R, Li L, et al. Blood pressure in relation to general and central adiposity among 500 000 adult Chinese men and women. International Journal of Epidemiology. PMID 25747585 DOI: 10.1093/ije/dyv012  1
2015 Qian Y, Pei D, Cheng T, Wu C, Pu X, Chen X, Liu Y, Shen H, Zhang W, Shu Y. CD137 ligand-mediated reverse signaling inhibits proliferation and induces apoptosis in non-small cell lung cancer. Medical Oncology (Northwood, London, England). 32: 44. PMID 25631633 DOI: 10.1007/s12032-015-0499-9  1
2015 Cho SJ, Teng IF, Zhang M, Yin T, Jung YS, Zhang J, Chen X. Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation. Oncotarget. 6: 305-16. PMID 25622105  0.56
2015 Zhang W, Zhu J, Song X, Xu Z, Xue X, Chen X, Yang X, Li Y, Dong X, Zhou S, Li W, Qian Y, Liu F, Su C. An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum. Parasites & Vectors. 8: 37. PMID 25604731 DOI: 10.1186/s13071-015-0650-7  1
2015 Cao R, Zhang J, Zhang M, Chen X. PPM1D regulates p21 expression via dephoshporylation at serine 123. Cell Cycle (Georgetown, Tex.). 14: 641-7. PMID 25590690 DOI: 10.4161/15384101.2014.994922  1
2015 Liu Y, Chen X, Gu Y, Zhu L, Qian Y, Pei D, Zhang W, Shu Y. FOXM1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and mediates sensitivity to cisplatin in A549 cells via the JNK/mitochondrial pathway. Neoplasma. 62: 61-71. PMID 25563368 DOI: 10.4149/neo_2015_008  1
2015 Huang X, Qian Y, Wu H, Xie X, Zhou Q, Wang Y, Kuang W, Shen L, Li K, Su J, Shen L, Chen X. Aberrant expression of osteopontin and E-cadherin indicates radiation resistance and poor prognosis for patients with cervical carcinoma. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 63: 88-98. PMID 25380749 DOI: 10.1369/0022155414561329  1
2015 Chen X, Qian Y, Wu S. The Warburg effect: evolving interpretations of an established concept. Free Radical Biology & Medicine. 79: 253-63. PMID 25277420 DOI: 10.1016/j.freeradbiomed.2014.08.027  1
2014 Zhang J, Xu E, Ren C, Yan W, Zhang M, Chen M, Cardiff RD, Imai DM, Wisner E, Chen X. Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: 18637-42. PMID 25512531 DOI: 10.1073/pnas.1415607112  1
2014 Kurmi OP, Li L, Smith M, Augustyn M, Chen J, Collins R, Guo Y, Han Y, Qin J, Xu G, Wang J, Bian Z, Zhou G, Davis K, Peto R, ... ... Chen X, ... ... Chen X, et al. Regional variations in the prevalence and misdiagnosis of air flow obstruction in China: baseline results from a prospective cohort of the China Kadoorie Biobank (CKB). Bmj Open Respiratory Research. 1: e000025. PMID 25478177 DOI: 10.1136/bmjresp-2014-000025  1
2014 Ren C, Cho SJ, Jung YS, Chen X. DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability. The Biochemical Journal. 464: 377-86. PMID 25268038 DOI: 10.1042/BJ20141164  0.56
2014 Xu C, Zhang X, Qian Y, Chen X, Liu R, Zeng G, Zhao H, Fang W. A high-throughput gene disruption methodology for the entomopathogenic fungus Metarhizium robertsii. Plos One. 9: e107657. PMID 25222118 DOI: 10.1371/journal.pone.0107657  1
2014 Yang WN, Ma KG, Chen XL, Shi LL, Bu G, Hu XD, Han H, Liu Y, Qian YH. Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells. Neuroscience. 278: 276-90. PMID 25168732 DOI: 10.1016/j.neuroscience.2014.08.013  0.36
2014 Yan W, Jung YS, Zhang Y, Chen X. Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase. Plos One. 9: e103497. PMID 25116336 DOI: 10.1371/journal.pone.0103497  0.56
2014 Chen X, Hu H, Qian Y, Shu J. Relation of late gadolinium enhancement in cardiac magnetic resonance on the diastolic volume recovery of left ventricle with hypertrophic cardiomyopathy. Journal of Thoracic Disease. 6: 988-94. PMID 25093097 DOI: 10.3978/j.issn.2072-1439.2014.06.37  1
2014 Han X, Yang Q, Lin L, Xu C, Zheng C, Chen X, Han Y, Li M, Cao W, Cao K, Chen Q, Xu G, Zhang Y, Zhang J, Schneider RJ, et al. Interleukin-17 enhances immunosuppression by mesenchymal stem cells. Cell Death and Differentiation. 21: 1758-68. PMID 25034782 DOI: 10.1038/cdd.2014.85  1
2014 Qian Y, Wang X, Liu Y, Li Y, Colvin RA, Tong L, Wu S, Chen X. Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells Cancer Letters. 351: 242-251. PMID 24973521 DOI: 10.1016/j.canlet.2014.06.008  1
2014 Qian Y, Ren H, Wang ZH, Li X, Chen XN, Chen N. Staging and risk factors of chronic kidney disease of outpatients in Shanghai. Renal Failure. 36: 1018-22. PMID 24940809 DOI: 10.3109/0886022X.2014.926923  1
2014 Pei D, Zhu F, Chen X, Qian J, He S, Qian Y, Shen H, Liu Y, Xu J, Shu Y. Pre-adjuvant chemotherapy leukocyte count may predict the outcome for advanced gastric cancer after radical resection. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 68: 213-7. PMID 24581723 DOI: 10.1016/j.biopha.2014.01.008  1
2014 Qian Y, Zhang J, Jung YS, Chen X. DEC1 coordinates with HDAC8 to differentially regulate TAp73 and ΔNp73 expression. Plos One. 9: e84015. PMID 24404147 DOI: 10.1371/journal.pone.0084015  1
2014 Xu E, Zhang J, Zhang M, Jiang Y, Cho SJ, Chen X. RNA-binding protein RBM24 regulates p63 expression via mRNA stability. Molecular Cancer Research : McR. 12: 359-69. PMID 24375645 DOI: 10.1158/1541-7786.MCR-13-0526  0.36
2014 Jiang Y, Zhang M, Qian Y, Xu E, Zhang J, Chen X. Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability. The Journal of Biological Chemistry. 289: 3164-75. PMID 24356969 DOI: 10.1074/jbc.M113.524413  1
2013 Zhang Y, Yan W, Chen X. Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells. Plos One. 8: e85624. PMID 24386484 DOI: 10.1371/journal.pone.0085624  0.32
2013 Zhang M, Zhang J, Chen X, Cho SJ, Chen X. Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1. Genes & Development. 27: 2246-58. PMID 24142875 DOI: 10.1101/gad.221739.113  0.36
2013 Cho SJ, Jung YS, Chen X. Poly (C)-binding protein 1 regulates p63 expression through mRNA stability. Plos One. 8: e71724. PMID 23940783 DOI: 10.1371/journal.pone.0071724  0.56
2013 Zhang J, Xu E, Chen X. Regulation of Mdm2 mRNA stability by RNA-binding protein RNPC1. Oncotarget. 4: 1121-2. PMID 23912475 DOI: 10.18632/oncotarget.1185  0.36
2013 Zhang Y, Yan W, Jung YS, Chen X. PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition. Plos One. 8: e66464. PMID 23805223 DOI: 10.1371/journal.pone.0066464  0.56
2013 Cho SJ, Rossi A, Jung YS, Yan W, Liu G, Zhang J, Zhang M, Chen X. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proceedings of the National Academy of Sciences of the United States of America. 110: 9362-7. PMID 23690620 DOI: 10.1073/pnas.1221242110  0.56
2013 Zhang J, Xu E, Chen X. TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function. The Journal of Biological Chemistry. 288: 7727-37. PMID 23362263 DOI: 10.1074/jbc.M112.429522  0.36
2013 Qian Y, Chen X. Senescence regulation by the p53 protein family. Methods in Molecular Biology (Clifton, N.J.). 965: 37-61. PMID 23296650 DOI: 10.1007/978-1-62703-239-1_3  1
2013 Yan W, Chen X, Zhang Y, Zhang J, Jung YS, Chen X. Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein. The Journal of Biological Chemistry. 288: 2907-13. PMID 23271742 DOI: 10.1074/jbc.M112.428607  0.56
2013 Jung YS, Qian Y, Yan W, Chen X. Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63. The Journal of Investigative Dermatology. 133: 1178-87. PMID 23235527 DOI: 10.1038/jid.2012.466  1
2012 Yan W, Zhang Y, Zhang J, Cho SJ, Chen X. HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via ΔNp63. Plos One. 7: e45336. PMID 23028944 DOI: 10.1371/journal.pone.0045336  0.36
2012 Qian Y, Jung YS, Chen X. DEC1 and MIC-1: new players of p53-dependent cell fate decision. Cell Cycle (Georgetown, Tex.). 11: 3525-6. PMID 22935706 DOI: 10.4161/cc.21962  1
2012 Seo Kw, Holt R, Jung YS, Rodriguez CO, Chen X, Rebhun RB. Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines. Plos One. 7: e42960. PMID 22927942 DOI: 10.1371/journal.pone.0042960  0.56
2012 Chen X, Zhang J, Zhang M, Liu S, Yan W, Jung J, Chen X. Serine 123 phosphorylation modulates p21 protein stability and activity by suppressing ubiquitin-independent proteasomal degradation. The Journal of Biological Chemistry. 287: 34410-8. PMID 22908227 DOI: 10.1074/jbc.M112.384990  0.36
2012 Berger CE, Qian Y, Liu G, Chen H, Chen X. p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells. The Journal of Biological Chemistry. 287: 30117-27. PMID 22787161 DOI: 10.1074/jbc.M112.367326  1
2012 Qian Y, Jung YS, Chen X. Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1. Proceedings of the National Academy of Sciences of the United States of America. 109: 11300-5. PMID 22723347 DOI: 10.1073/pnas.1203185109  1
2012 Hertwig F, Meyer K, Braun S, Ek S, Spang R, Pfenninger CV, Artner I, Prost G, Chen X, Biegel JA, Judkins AR, Englund E, Nuber UA. Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. Cancer Research. 72: 3381-92. PMID 22719073 DOI: 10.1158/0008-5472.CAN-11-3525  1
2012 Jung YS, Qian Y, Chen X. Pirh2 RING-finger E3 ubiquitin ligase: its role in tumorigenesis and cancer therapy. Febs Letters. 586: 1397-402. PMID 22673504 DOI: 10.1016/j.febslet.2012.03.052  1
2012 Yan W, Zhang J, Zhang Y, Jung YS, Chen X. p73 expression is regulated by RNPC1, a target of the p53 family, via mRNA stability. Molecular and Cellular Biology. 32: 2336-48. PMID 22508983 DOI: 10.1128/MCB.00215-12  0.56
2012 Nadiminty N, Tummala R, Lou W, Zhu Y, Shi XB, Zou JX, Chen H, Zhang J, Chen X, Luo J, deVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. Plos One. 7: e32832. PMID 22479342 DOI: 10.1371/journal.pone.0032832  1
2012 Zhang Y, Yan W, Jung YS, Chen X. Mammary epithelial cell polarity is regulated differentially by p73 isoforms via epithelial-to-mesenchymal transition. The Journal of Biological Chemistry. 287: 17746-53. PMID 22457351 DOI: 10.1074/jbc.M112.358143  0.56
2012 Cho SJ, Jung YS, Zhang J, Chen X. The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation. The Journal of Biological Chemistry. 287: 14535-44. PMID 22371495 DOI: 10.1074/jbc.M111.326827  0.56
2012 Nadiminty N, Tummala R, Lou W, Zhu Y, Zhang J, Chen X, eVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. The Journal of Biological Chemistry. 287: 1527-37. PMID 22128178 DOI: 10.1074/jbc.M111.278705  1
2012 Jung YS, Qian Y, Chen X. DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation. Dna Repair. 11: 177-84. PMID 22056306 DOI: 10.1016/j.dnarep.2011.10.017  1
2011 Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, ... ... Chen X, et al. Role of Pirh2 in mediating the regulation of p53 and c-Myc. Plos Genetics. 7: e1002360. PMID 22125490 DOI: 10.1371/journal.pgen.1002360  1
2011 Zhang J, Chen X. Novel role of Wip1 in p53-mediated cell homeostasis under non-stress conditions. Cell Cycle (Georgetown, Tex.). 10: 3235. PMID 21946519 DOI: 10.4161/cc.10.19.17128  0.36
2011 Jung YS, Qian Y, Chen X. The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation. The Journal of Biological Chemistry. 286: 35388-95. PMID 21852228 DOI: 10.1074/jbc.M111.261537  1
2011 Jung YS, Hakem A, Hakem R, Chen X. Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis. Molecular and Cellular Biology. 31: 3997-4006. PMID 21791603 DOI: 10.1128/MCB.05808-11  0.56
2011 Zhang J, Cho SJ, Shu L, Yan W, Guerrero T, Kent M, Skorupski K, Chen H, Chen X. Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes & Development. 25: 1528-43. PMID 21764855 DOI: 10.1101/gad.2069311  0.36
2011 Zhang Y, Yan W, Chen X. Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions. The Journal of Biological Chemistry. 286: 16218-28. PMID 21454711 DOI: 10.1074/jbc.M110.214585  0.32
2011 Yan W, Zhang Y, Zhang J, Liu S, Cho SJ, Chen X. Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression. The Journal of Biological Chemistry. 286: 17478-86. PMID 21454520 DOI: 10.1074/jbc.M111.231639  0.36
2011 Qian Y, Jung YS, Chen X. DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiation. The Journal of Biological Chemistry. 286: 12033-41. PMID 21317427 DOI: 10.1074/jbc.M110.207241  1
2011 Scoumanne A, Cho SJ, Zhang J, Chen X. The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability. Nucleic Acids Research. 39: 213-24. PMID 20817677 DOI: 10.1093/nar/gkq778  0.36
2010 Zhang Y, Scoumanne A, Chen X. G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery. Molecular and Cellular Pharmacology. 2: 111-116. PMID 20686680  0.36
2010 Zhang J, Jun Cho S, Chen X. RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability. Proceedings of the National Academy of Sciences of the United States of America. 107: 9614-9. PMID 20457941 DOI: 10.1073/pnas.0912594107  0.36
2010 Qian Y, Chen X. Tumor suppression by p53: making cells senescent. Histology and Histopathology. 25: 515-26. PMID 20183804  1
2010 Jung YS, Qian Y, Chen X. Examination of the expanding pathways for the regulation of p21 expression and activity. Cellular Signalling. 22: 1003-12. PMID 20100570 DOI: 10.1016/j.cellsig.2010.01.013  1
2010 Cho SJ, Zhang J, Chen X. RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability. Nucleic Acids Research. 38: 2256-67. PMID 20064878 DOI: 10.1093/nar/gkp1229  0.36
2010 Jung YS, Liu G, Chen X. Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation. Molecular and Cellular Biology. 30: 1041-8. PMID 20008555 DOI: 10.1128/MCB.01198-09  0.56
2009 Zhang Y, Qian Y, Lu W, Chen X. The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress. Cancer Research. 69: 6049-56. PMID 19602589 DOI: 10.1158/0008-5472.CAN-09-0621  1
2009 Zhang J, Chen X, Kent MS, Rodriguez CO, Chen X. Establishment of a dog model for the p53 family pathway and identification of a novel isoform of p21 cyclin-dependent kinase inhibitor. Molecular Cancer Research : McR. 7: 67-78. PMID 19147538 DOI: 10.1158/1541-7786.MCR-08-0347  0.36
2008 Zhang J, Chen X. Posttranscriptional regulation of p53 and its targets by RNA-binding proteins. Current Molecular Medicine. 8: 845-9. PMID 19075680  0.36
2008 Zhang Y, Shu L, Chen X. Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival. The Journal of Biological Chemistry. 283: 30689-98. PMID 18779328 DOI: 10.1074/jbc.M801711200  0.32
2008 Yan W, Liu G, Scoumanne A, Chen X. Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. Cancer Research. 68: 6789-96. PMID 18701504 DOI: 10.1158/0008-5472.CAN-08-0810  0.36
2008 Qian Y, Chen X. ID1, inhibitor of differentiation/DNA binding, is an effector of the p53-dependent DNA damage response pathway. The Journal of Biological Chemistry. 283: 22410-6. PMID 18556654 DOI: 10.1074/jbc.M800643200  1
2008 Helton ES, Zhang J, Chen X. The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63. Oncogene. 27: 2843-50. PMID 18037962 DOI: 10.1038/sj.onc.1210948  1
2008 Qian Y, Zhang J, Yan B, Chen X. DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. The Journal of Biological Chemistry. 283: 2896-905. PMID 18025081 DOI: 10.1074/jbc.M708624200  1
2007 Xu Y, Zhang J, Chen X. The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes. The Journal of Biological Chemistry. 282: 37429-35. PMID 17938176 DOI: 10.1074/jbc.M706039200  0.36
2007 Zhang J, Chen X. The p53 family: prospect for cancer gene therapy. Cancer Biology & Therapy. 6: 116-8. PMID 17612008  0.36
2007 Song L, Yan W, Chen X, Deng CX, Wang Q, Jiao K. Myocardial smad4 is essential for cardiogenesis in mouse embryos. Circulation Research. 101: 277-85. PMID 17585069 DOI: 10.1161/CIRCRESAHA.107.155630  1
2007 Harms KL, Chen X. Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity. Cancer Research. 67: 3145-52. PMID 17409421 DOI: 10.1158/0008-5472.CAN-06-4397  1
2007 Scoumanne A, Chen X. The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners. The Journal of Biological Chemistry. 282: 15471-5. PMID 17409384 DOI: 10.1074/jbc.M701023200  0.36
2007 Zhang J, Chen X. DeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkA. Molecular and Cellular Biology. 27: 3868-80. PMID 17353261 DOI: 10.1128/MCB.02112-06  0.36
2007 Geng Y, Akhtar RS, Shacka JJ, Klocke BJ, Zhang J, Chen X, Roth KA. p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis. Journal of Neuropathology and Experimental Neurology. 66: 66-74. PMID 17204938 DOI: 10.1097/nen.0b013e31802d4ab4  1
2007 Helton ES, Chen X. p53 modulation of the DNA damage response. Journal of Cellular Biochemistry. 100: 883-96. PMID 17031865 DOI: 10.1002/jcb.21091  1
2006 Scoumanne A, Chen X. The epithelial cell transforming sequence 2, a guanine nucleotide exchange factor for Rho GTPases, is repressed by p53 via protein methyltransferases and is required for G1-S transition. Cancer Research. 66: 6271-9. PMID 16778203 DOI: 10.1158/0008-5472.CAN-06-0121  0.36
2006 Harms KL, Chen X. p19ras brings a new twist to the regulation of p73 by Mdm2. Science's Stke : Signal Transduction Knowledge Environment. 2006: pe24. PMID 16738062 DOI: 10.1126/stke.3372006pe24  1
2006 Harms KL, Chen X. The functional domains in p53 family proteins exhibit both common and distinct properties. Cell Death and Differentiation. 13: 890-7. PMID 16543939 DOI: 10.1038/sj.cdd.4401904  1
2006 Jung EJ, Liu G, Zhou W, Chen X. Myosin VI is a mediator of the p53-dependent cell survival pathway. Molecular and Cellular Biology. 26: 2175-86. PMID 16507995 DOI: 10.1128/MCB.26.6.2175-2186.2006  1
2006 Liu G, Chen X. DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. Molecular and Cellular Biology. 26: 1398-413. PMID 16449651 DOI: 10.1128/MCB.26.4.1398-1413.2006  0.32
2006 Helton ES, Zhu J, Chen X. The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63. The Journal of Biological Chemistry. 281: 2533-42. PMID 16319057 DOI: 10.1074/jbc.M507964200  1
2006 Liu G, Chen X. Regulation of the p53 transcriptional activity. Journal of Cellular Biochemistry. 97: 448-58. PMID 16288459 DOI: 10.1002/jcb.20700  0.32
2005 Scoumanne A, Harms KL, Chen X. Structural basis for gene activation by p53 family members. Cancer Biology & Therapy. 4: 1178-85. PMID 16294021  1
2005 Li M, Zhang Z, Hill DL, Chen X, Wang H, Zhang R. Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels. Cancer Research. 65: 8200-8. PMID 16166295 DOI: 10.1158/0008-5472.CAN-05-1302  1
2005 Liu G, Chen X. The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73. The Journal of Biological Chemistry. 280: 20111-9. PMID 15769743 DOI: 10.1074/jbc.M413889200  0.32
2005 Harms KL, Chen X. The C terminus of p53 family proteins is a cell fate determinant. Molecular and Cellular Biology. 25: 2014-30. PMID 15713654 DOI: 10.1128/MCB.25.5.2014-2030.2005  1
2004 Willis A, Jung EJ, Wakefield T, Chen X. Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes. Oncogene. 23: 2330-8. PMID 14743206 DOI: 10.1038/sj.onc.1207396  1
2004 Liu G, Nozell S, Xiao H, Chen X. DeltaNp73beta is active in transactivation and growth suppression. Molecular and Cellular Biology. 24: 487-501. PMID 14701724  0.32
2003 Watcharasit P, Bijur GN, Song L, Zhu J, Chen X, Jope RS. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. The Journal of Biological Chemistry. 278: 48872-9. PMID 14523002 DOI: 10.1074/jbc.M305870200  1
2003 Willis AC, Pipes T, Zhu J, Chen X. p73 can suppress the proliferation of cells that express mutant p53. Oncogene. 22: 5481-95. PMID 12934108 DOI: 10.1038/sj.onc.1206505  0.68
2003 Nozell S, Wu Y, McNaughton K, Liu G, Willis A, Paik JC, Chen X. Characterization of p73 functional domains necessary for transactivation and growth suppression. Oncogene. 22: 4333-47. PMID 12853970 DOI: 10.1038/sj.onc.1206470  1
2003 Chen X, Liu G, Zhu J, Jiang J, Nozell S, Willis A. Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family. Cancer Biology & Therapy. 2: 55-62. PMID 12673118  0.68
2003 Liu G, Xia T, Chen X. The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein. The Journal of Biological Chemistry. 278: 17557-65. PMID 12609999 DOI: 10.1074/jbc.M210696200  0.32
2002 Liu G, Chen X. The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis. Oncogene. 21: 7195-204. PMID 12370809 DOI: 10.1038/sj.onc.1205862  0.32
2002 Watcharasit P, Bijur GN, Zmijewski JW, Song L, Zmijewska A, Chen X, Johnson GV, Jope RS. Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 99: 7951-5. PMID 12048243 DOI: 10.1073/pnas.122062299  1
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