Thea D. Tlsty - Publications

Affiliations: 
Cell Biology University of California, San Francisco, San Francisco, CA 
Area:
Oncology, Cell Biology

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pan D, Roy S, Gascard P, Zhao J, Chen-Tanyolac C, Tlsty TD. SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. Cellular Signalling. PMID 27705752 DOI: 10.1016/j.cellsig.2016.09.008  0.64
2016 Gascard P, Tlsty TD. Carcinoma-associated fibroblasts: orchestrating the composition of malignancy. Genes & Development. 30: 1002-19. PMID 27151975 DOI: 10.1101/gad.279737.116  0.64
2015 Elliott G, Hong C, Xing X, Zhou X, Li D, Coarfa C, Bell RJ, Maire CL, Ligon KL, Sigaroudinia M, Gascard P, Tlsty TD, Harris RA, Schalkwyk LC, Bilenky M, et al. Intermediate DNA methylation is a conserved signature of genome regulation. Nature Communications. 6: 6363. PMID 25691127 DOI: 10.1038/ncomms7363  0.64
2015 Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, ... ... Tlsty TD, et al. Epigenetic and transcriptional determinants of the human breast. Nature Communications. 6: 6351. PMID 25690954 DOI: 10.1038/ncomms7351  0.64
2014 Lowdon RF, Zhang B, Bilenky M, Mauro T, Li D, Gascard P, Sigaroudinia M, Farnham PJ, Bastian BC, Tlsty TD, Marra MA, Hirst M, Costello JF, Wang T, Cheng JB. Regulatory network decoded from epigenomes of surface ectoderm-derived cell types. Nature Communications. 5: 5442. PMID 25421844 DOI: 10.1038/ncomms6442  0.64
2014 DeFilippis RA, Fordyce C, Patten K, Chang H, Zhao J, Fontenay GV, Kerlikowske K, Parvin B, Tlsty TD. Stress signaling from human mammary epithelial cells contributes to phenotypes of mammographic density. Cancer Research. 74: 5032-44. PMID 25172842 DOI: 10.1158/0008-5472.CAN-13-3390  0.64
2014 Liao D, Tlsty TD. Evolutionary game theory for physical and biological scientists. II. Population dynamics equations can be associated with interpretations. Interface Focus. 4: 20140038. PMID 25097752 DOI: 10.1098/rsfs.2014.0038  0.64
2014 Liao D, Tlsty TD. Evolutionary game theory for physical and biological scientists. I. Training and validating population dynamics equations. Interface Focus. 4: 20140037. PMID 25097751 DOI: 10.1098/rsfs.2014.0037  0.64
2014 Wu A, Liao D, Tlsty TD, Sturm JC, Austin RH. Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment. Interface Focus. 4: 20140028. PMID 25097749 DOI: 10.1098/rsfs.2014.0028  0.64
2013 Wu A, Loutherback K, Lambert G, Estévez-Salmerón L, Tlsty TD, Austin RH, Sturm JC. Cell motility and drug gradients in the emergence of resistance to chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. 110: 16103-8. PMID 24046372 DOI: 10.1073/pnas.1314385110  0.64
2013 Zhang B, Zhou Y, Lin N, Lowdon RF, Hong C, Nagarajan RP, Cheng JB, Li D, Stevens M, Lee HJ, Xing X, Zhou J, Sundaram V, Elliott G, Gu J, ... ... Tlsty TD, et al. Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm. Genome Research. 23: 1522-40. PMID 23804400 DOI: 10.1101/gr.156539.113  0.64
2013 Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, et al. DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nature Genetics. 45: 836-41. PMID 23708189 DOI: 10.1038/ng.2649  0.64
2013 Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Tlsty TD, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/srep01449  0.64
2013 Roy S, Gascard P, Dumont N, Zhao J, Pan D, Petrie S, Margeta M, Tlsty TD. Rare somatic cells from human breast tissue exhibit extensive lineage plasticity. Proceedings of the National Academy of Sciences of the United States of America. 110: 4598-603. PMID 23487770 DOI: 10.1073/pnas.1218682110  0.64
2013 Dumont N, Liu B, Defilippis RA, Chang H, Rabban JT, Karnezis AN, Tjoe JA, Marx J, Parvin B, Tlsty TD. Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia (New York, N.Y.). 15: 249-62. PMID 23479504 DOI: 10.1593/neo.121950  0.64
2012 DeFilippis RA, Tlsty TD. Hello out there...is anybody listening? Cancer Discovery. 2: 1084-6. PMID 23230186 DOI: 10.1158/2159-8290.CD-12-0434  0.64
2012 Fordyce CA, Patten KT, Fessenden TB, DeFilippis R, Hwang ES, Zhao J, Tlsty TD. Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes. Breast Cancer Research : Bcr. 14: R155. PMID 23216814 DOI: 10.1186/bcr3368  0.64
2012 Liao D, Estévez-Salmerón L, Tlsty TD. Generalized principles of stochasticity can be used to control dynamic heterogeneity. Physical Biology. 9: 065006. PMID 23197162 DOI: 10.1088/1478-3975/9/6/065006  0.64
2012 Liao D, Estévez-Salmerón L, Tlsty TD. Conceptualizing a tool to optimize therapy based on dynamic heterogeneity. Physical Biology. 9: 065005. PMID 23197078 DOI: 10.1088/1478-3975/9/6/065005  0.64
2012 DeFilippis RA, Chang H, Dumont N, Rabban JT, Chen YY, Fontenay GV, Berman HK, Gauthier ML, Zhao J, Hu D, Marx JJ, Tjoe JA, Ziv E, Febbraio M, Kerlikowske K, ... ... Tlsty TD, et al. CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues. Cancer Discovery. 2: 826-39. PMID 22777768 DOI: 10.1158/2159-8290.CD-12-0107  0.64
2011 Radisky DC, Santisteban M, Berman HK, Gauthier ML, Frost MH, Reynolds CA, Vierkant RA, Pankratz VS, Visscher DW, Tlsty TD, Hartmann LC. p16 INK4a expression and breast cancer risk in women with atypical hyperplasia Cancer Prevention Research. 4: 1953-1960. PMID 21920875 DOI: 10.1158/1940-6207.CAPR-11-0282  0.64
2011 Lambert G, Estévez-Salmeron L, Oh S, Liao D, Emerson BM, Tlsty TD, Austin RH. An analogy between the evolution of drug resistance in bacterial communities and malignant tissues. Nature Reviews. Cancer. 11: 375-82. PMID 21508974 DOI: 10.1038/nrc3039  0.64
2011 Dvorak HF, Weaver VM, Tlsty TD, Bergers G. Tumor microenvironment and progression. Journal of Surgical Oncology. 103: 468-74. PMID 21480238 DOI: 10.1002/jso.21709  0.64
2011 Tlsty TD. A twist of cell fate. Cell Stem Cell. 8: 126-7. PMID 21295267 DOI: 10.1016/j.stem.2011.01.004  0.64
2010 Kerlikowske K, Molinaro AM, Gauthier ML, Berman HK, Waldman F, Bennington J, Sanchez H, Jimenez C, Stewart K, Chew K, Ljung BM, Tlsty TD. Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis. Journal of the National Cancer Institute. 102: 627-37. PMID 20427430 DOI: 10.1093/jnci/djq101  0.64
2010 McDermott KM, Liu BY, Tlsty TD, Pazour GJ. Primary cilia regulate branching morphogenesis during mammary gland development. Current Biology : Cb. 20: 731-7. PMID 20381354 DOI: 10.1016/j.cub.2010.02.048  0.64
2009 Dumont N, Crawford YG, Sigaroudinia M, Nagrani SS, Wilson MB, Buehring GC, Turashvili G, Aparicio S, Gauthier ML, Fordyce CA, McDermott KM, Tlsty TD. Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy. Breast Cancer Research : Bcr. 11: R87. PMID 19995452 DOI: 10.1186/bcr2457  0.64
2009 Dumont N, Tlsty TD. Reflections on miR-ing effects in metastasis. Cancer Cell. 16: 3-4. PMID 19573805 DOI: 10.1016/j.ccr.2009.06.013  0.64
2009 Chang H, DeFilippis RA, Tlsty TD, Parvin B. Graphical methods for quantifying macromolecules through bright field imaging. Bioinformatics (Oxford, England). 25: 1070-5. PMID 18703588 DOI: 10.1093/bioinformatics/btn426  0.64
2008 Dumont N, Wilson MB, Crawford YG, Reynolds PA, Sigaroudinia M, Tlsty TD. Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 14867-72. PMID 18806226 DOI: 10.1073/pnas.0807146105  0.64
2008 Jones PA, Archer TK, Baylin SB, Beck S, Berger S, Bernstein BE, Carpten JD, Clark SJ, Costello JF, Doerge RW, Esteller M, Feinberg AP, Gingeras TR, Greally JM, Henikoff S, ... ... Tlsty TD, et al. Moving AHEAD with an international human epigenome project Nature. 454: 711-715. PMID 18685699 DOI: 10.1038/454711a  0.64
2008 Chang H, DeFilippis RA, Tlsty TD, Parvin B. Scoring histological sections through immunohistochemistry 2008 5th Ieee International Symposium On Biomedical Imaging: From Nano to Macro, Proceedings, Isbi. 344-347. DOI: 10.1109/ISBI.2008.4541003  0.64
2007 Bean GR, Bryson AD, Pilie PG, Goldenberg V, Baker JC, Ibarra C, Brander DM, Paisie C, Case NR, Gauthier M, Reynolds PA, Dietze E, Ostrander J, Scott V, Wilke LG, ... ... Tlsty TD, et al. Morphologically normal-appearing mammary epithelial cells obtained from high-risk women exhibit methylation silencing of INK4a/ARF. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6834-41. PMID 18006786 DOI: 10.1158/1078-0432.CCR-07-0407  0.64
2007 Gauthier ML, Berman HK, Miller C, Kozakeiwicz K, Chew K, Moore D, Rabban J, Chen YY, Kerlikowske K, Tlsty TD. Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell. 12: 479-91. PMID 17996651 DOI: 10.1016/j.ccr.2007.10.017  0.64
2007 Tlsty TD. Luminal cells GATA have it. Nature Cell Biology. 9: 135-6. PMID 17268476 DOI: 10.1038/ncb0207-135  0.64
2006 Tlsty TD, Coussens LM. Tumor stroma and regulation of cancer development. Annual Review of Pathology. 1: 119-50. PMID 18039110 DOI: 10.1146/annurev.pathol.1.110304.100224  0.64
2006 Zhang J, Pickering CR, Holst CR, Gauthier ML, Tlsty TD. p16INK4a modulates p53 in primary human mammary epithelial cells. Cancer Research. 66: 10325-31. PMID 17079452 DOI: 10.1158/0008-5472.CAN-06-1594  0.64
2006 Grant MR, Mostov KE, Tlsty TD, Hunt CA. Simulating properties of in vitro epithelial cell morphogenesis. Plos Computational Biology. 2: e129. PMID 17029556 DOI: 10.1371/journal.pcbi.0020129  0.64
2006 Reynolds PA, Sigaroudinia M, Zardo G, Wilson MB, Benton GM, Miller CJ, Hong C, Fridlyand J, Costello JF, Tlsty TD. Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells. The Journal of Biological Chemistry. 281: 24790-802. PMID 16766534 DOI: 10.1074/jbc.M604175200  0.64
2006 McDermott KM, Zhang J, Holst CR, Kozakiewicz BK, Singla V, Tlsty TD. p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells. Plos Biology. 4: e51. PMID 16464125 DOI: 10.1371/journal.pbio.0040051  0.64
2005 Berman H, Zhang J, Crawford YG, Gauthier ML, Fordyce CA, McDermott KM, Sigaroudinia M, Kozakiewicz K, Tlsty TD. Genetic and epigenetic changes in mammary epithelial cells identify a subpopulation of cells involved in early carcinogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 70: 317-27. PMID 16869768 DOI: 10.1101/sqb.2005.70.051  0.64
2005 Gauthier ML, Pickering CR, Miller CJ, Fordyce CA, Chew KL, Berman HK, Tlsty TD. p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue. Cancer Research. 65: 1792-9. PMID 15753376 DOI: 10.1158/0008-5472.CAN-04-3507  0.64
2004 Tlsty TD, Crawford YG, Holst CR, Fordyce CA, Zhang J, McDermott K, Kozakiewicz K, Gauthier ML. Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis. Journal of Mammary Gland Biology and Neoplasia. 9: 263-74. PMID 15557799 DOI: 10.1023/B:JOMG.0000048773.95897.5f  0.64
2004 Crawford YG, Gauthier ML, Joubel A, Mantei K, Kozakiewicz K, Afshari CA, Tlsty TD. Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program. Cancer Cell. 5: 263-73. PMID 15050918 DOI: 10.1016/S1535-6108(04)00023-6  0.64
2003 Shim V, Gauthier ML, Sudilovsky D, Mantei K, Chew KL, Moore DH, Cha I, Tlsty TD, Esserman LJ. Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium. Cancer Research. 63: 2347-50. PMID 12750248  0.64
2003 Holst CR, Nuovo GJ, Esteller M, Chew K, Baylin SB, Herman JG, Tlsty TD. Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Research. 63: 1596-601. PMID 12670910  0.64
2002 Tlsty TD. Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer. Cancer Cell. 2: 2-4. PMID 12150817 DOI: 10.1016/S1535-6108(02)00088-0  0.64
2001 Meng MV, Grossfeld GD, Williams GH, Dilworth S, Stoeber K, Mulley TW, Weinberg V, Carroll PR, Tlsty TD. Minichromosome maintenance protein 2 expression in prostate: Characterization and association with outcome after therapy for cancer Clinical Cancer Research. 7: 2712-2718. PMID 11555583  0.64
2001 Tlsty TD, Romanov SR, Kozakiewicz BK, Holst CR, Haupt LM, Crawford YG. Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence. Journal of Mammary Gland Biology and Neoplasia. 6: 235-43. PMID 11501583 DOI: 10.1023/A:1011369026168  0.64
2001 Stoeber K, Tlsty TD, Happerfield L, Thomas GA, Romanov S, Bobrow L, Williams ED, Williams GH. DNA replication licensing and human cell proliferation. Journal of Cell Science. 114: 2027-41. PMID 11493639  0.64
2001 Tlsty TD. Stromal cells can contribute oncogenic signals Seminars in Cancer Biology. 11: 97-104. PMID 11322829 DOI: 10.1006/scbi.2000.0361  0.64
2001 Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature. 409: 633-7. PMID 11214324 DOI: 10.1038/35054579  0.64
2001 Tlsty TD, Hein PW. Know thy neighbor: stromal cells can contribute oncogenic signals. Current Opinion in Genetics & Development. 11: 54-9. PMID 11163151 DOI: 10.1016/S0959-437X(00)00156-8  0.64
2001 Tlsty TD. Searching for targets: The power of somatic cell genetics Genome Research. 11: 187-188. PMID 11157780 DOI: 10.1101/gr.177101  0.64
1999 Meyer KM, Hess SM, Tlsty TD, Leadon SA. Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light. Oncogene. 18: 5795-805. PMID 10523860 DOI: 10.1038/sj.onc.1202977  0.64
1999 Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium Cancer Research. 59: 5002-5011. PMID 10519415  0.64
1999 Jiang XR, Jimenez G, Chang E, Frolkis M, Kusler B, Sage M, Beeche M, Bodnar AG, Wahl GM, Tlsty TD, Chiu CP. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nature Genetics. 21: 111-4. PMID 9916802 DOI: 10.1038/5056  0.64
1999 Tlsty TD. A molecular blueprint for targeting cancer? Nature Genetics. 21: 64-65. PMID 9916789 DOI: 10.1038/4998  0.64
1998 Tlsty TD. Cell-adhesion-dependent influences on genomic instability and carcinogenesis Current Opinion in Cell Biology. 10: 647-653. PMID 9818176 DOI: 10.1016/S0955-0674(98)80041-0  0.64
1998 Olumi AF, Dazin P, Tlsty TD. A novel coculture technique demonstrates that normal human prostatic fibroblasts contribute to tumor formation of LNCaP cells by retarding cell death Cancer Research. 58: 4525-4530. PMID 9788594  0.64
1998 Gonzales AJ, Christensen JG, Preston RJ, Goldsworthy TL, Tlsty TD, Fox TR. Attenuation of G1 checkpoint function by the non-genotoxic carcinogen phenobarbital Carcinogenesis. 19: 1173-1183. PMID 9683175 DOI: 10.1093/carcin/19.7.1173  0.64
1998 Hayward SW, Grossfeld GD, Tlsty TD, Cunha GR. Genetic and epigenetic influences in prostatic carcinogenesis (review) International Journal of Oncology. 13: 35-47. PMID 9625801  0.64
1998 Gualberto A, Aldape K, Kozakiewicz K, Tlsty TD. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control Proceedings of the National Academy of Sciences of the United States of America. 95: 5166-5171. PMID 9560247 DOI: 10.1073/pnas.95.9.5166  0.64
1998 Grossfeld GD, Hayward SW, Tlsty TD, Cunha GR. The role of stroma in prostatic carcinogenesis Endocrine-Related Cancer. 5: 253-270. DOI: 10.1677/erc.0.0050253  0.64
1997 Hall IJ, Gioeli D, Weissman BE, Tlsty TD. Identification of additional complementation groups that regulate genomic instability Genes Chromosomes and Cancer. 20: 103-112. PMID 9331561 DOI: 10.1002/(SICI)1098-2264(199710)20:2<103::AID-GCC1>3.0.CO;2-7  0.64
1997 Nigro JM, Aldape KD, Hess SM, Tlsty TD. Cellular adhesion regulates p53 protein levels in primary human keratinocytes. Cancer Research. 57: 3635-9. PMID 9288761  0.64
1997 Tlsty TD. Genomic instability and its role in neoplasia Current Topics in Microbiology and Immunology. 221: 37-46. PMID 8979439  0.64
1996 Tlsty TD. Regulation of genomic instability in preneoplastic cells Cancer Surveys. 28: 217-224. PMID 8977037  0.64
1996 Chen CYM, Hall I, Lansing TJ, Gilmer TM, Tlsty TD, Kastan MB. Separate pathways for p53 induction by ionizing radiation and N- (phosphonoacetyl)-L-aspartate Cancer Research. 56: 3659-3662. PMID 8706003  0.64
1996 Xiong Y, Kuppuswamy D, Li Y, Livanos EM, Hixon M, White A, Beach D, Tlsty TD. Alteration of cell cycle kinase complexes in human papillomavirus E6- and E7-expressing fibroblasts precedes neoplastic transformation. Journal of Virology. 70: 999-1008. PMID 8551641  0.64
1996 Tlsty TD. [22]Gene amplification as marker for studying genomic instability Methods in Molecular Genetics. 8: 388-401. DOI: 10.1016/S1067-2389(96)80055-0  0.64
1996 Tlsty TD. Extended abstract: Abrogation of cell cycle checkpoint control in preneoplastic cells Radiation Oncology Investigations. 3: 320-322.  0.64
1995 Paules RS, Levedakou EN, Wilson SJ, Innes CL, Rhodes N, Tlsty TD, Galloway DA, Donehower LA, Tainsky MA, Kaufmann WK. Defective G2 checkpoint function in cells from individuals with familial cancer syndromes. Cancer Research. 55: 1763-73. PMID 7712486  0.64
1995 Tlsty TD, Briot A, Gualberto A, Hall I, Hess S, Hixon M, Kuppuswamy D, Romanov S, Sage M, White A. Genomic instability and cancer. Mutation Research. 337: 1-7. PMID 7596354 DOI: 10.1016/0921-8777(95)00016-D  0.64
1995 Tlsty TD. Cell cycle control and genomic instability Cancer and Metastasis Reviews. 14: 1-2.  0.64
1994 White AE, Livanos EM, Tlsty TD. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes & Development. 8: 666-77. PMID 7926757  0.64
1994 Forrester K, Kispert J, Sanchez JH, Gerwin BI, Tlsty TD, Harris CC. Clonal variation of tumorigenic potential in v-Ha-ras-transformed human bronchial epithelial cells: relationship to ras oncogene expression and CAD gene amplification. Molecular Carcinogenesis. 11: 34-41. PMID 7916988 DOI: 10.1002/mc.2940110107  0.64
1994 Tlsty TD, White A, Livanos E, Sage M, Roelofs H, Briot A, Poulose B. Genomic integrity and the genetics of cancer. Cold Spring Harbor Symposia On Quantitative Biology. 59: 265-75. PMID 7587078  0.64
1993 Schaefer DI, Livanos EM, White AE, Tlsty TD. Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts. Cancer Research. 53: 4946-51. PMID 8402685  0.64
1993 Jonczyk P, White A, Lum K, Carl Barrett J, Tlsty TD. Amplification Potential in Preneoplastic and Neoplastic Syrian Hamster Embryo Fibroblasts Transformed by Various Carcinogens Cancer Research. 53: 3098-3102. PMID 8319217  0.64
1993 Tlsty TD, Jonczyk P, White A, Sage M, Hall I, Schaefer D, Briot A, Livanos E, Roelofs H, Poulose B, Sanchez J. Loss of chromosomal integrity in neoplasia Cold Spring Harbor Symposia On Quantitative Biology. 58: 645-654. PMID 7956081  0.64
1992 Tlsty TD, White A, Sanchez J. Suppression of gene amplification in human cell hybrids Science. 255: 1425-1427. PMID 1542791  0.64
1992 Livingstone LR, White A, Sprouse J, Livanos E, Jacks T, Tlsty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell. 70: 923-35. PMID 1356076 DOI: 10.1016/0092-8674(92)90243-6  0.64
1990 Tlsty TD, Adams P. Replication of the dihydrofolate reductase genes on double minute chromosomes in a murine cell line Experimental Cell Research. 188: 164-168. PMID 2328775 DOI: 10.1016/0014-4827(90)90293-J  0.64
1990 Tlsty TD. Normal diploid human and rodent cells lack a detectable frequency of gene amplification Proceedings of the National Academy of Sciences of the United States of America. 87: 3132-3136. PMID 2326271  0.64
1989 Otto E, McCord S, Tlsty TD. Increased incidence of CAD gene amplification in tumorigenic rat lines as an indicator of genomic instability of neoplastic cells Journal of Biological Chemistry. 264: 3390-3396. PMID 2914957  0.64
1989 Tlsty TD, Margolin BH, Lum K. Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis. Proceedings of the National Academy of Sciences of the United States of America. 86: 9441-5. PMID 2687881 DOI: 10.1073/pnas.86.23.9441  0.64
1989 Goz B, Carl PL, Tlsty TD. 1-β-D-Arabinofuranosylcytosine enhancement of resistance to several antineoplastic drugs in mammalian tissue culture cells Molecular Pharmacology. 36: 360-365. PMID 2571071  0.64
1984 Tlsty TD, Brown PC, Schimke RT. UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells. Molecular and Cellular Biology. 4: 1050-6. PMID 6738530  0.64
1984 Tlsty TD, Albertini AM, Miller JH. Gene amplification in the lac region of E. coli Cell. 37: 217-224. PMID 6327052 DOI: 10.1016/0092-8674(84)90317-9  0.64
1983 Brown PC, Tlsty TD, Schimke RT. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea. Molecular and Cellular Biology. 3: 1097-107. PMID 6877240  0.64
1982 Albertini AM, Hofer M, Calos MP, Tlsty TD, Miller JH. Analysis of spontaneous deletions and gene amplification in the lac region of Escherichia coli Cold Spring Harbor Symposia On Quantitative Biology. 47: 841-850. PMID 6345079  0.64
1981 Berg DE, Egner C, Hirschel BJ, Howard J, Johnsrud L, Jorgensen RA, Tlsty TD. Insertion, excision, and inversion of Tn5 Cold Spring Harbor Symposia On Quantitative Biology. 45: 115-123. PMID 6271454  0.64
1978 Smerdon MJ, Tlsty TD, Lieberman MW. Distribution of ultraviolet-induced DNA repair synthesis in nuclease sensitive and resistant regions of human chromatin Biochemistry. 17: 2377-2386. PMID 678515  0.64
1975 Wilkinson DS, Tlsty TD, Hanas RJ. The inhibition of ribosomal RNA synthesis and maturation in Novikoff hepatoma cells by 5-fluorouridine. Cancer Research. 35: 3014-20. PMID 171060  0.64
1975 Wilkinson DS, Tlsty TD, Hanas RJ. The inhibition of ribosomal RNA synthesis and maturation in Novikoff hepatoma cells by 5 fluorouridine Cancer Research. 35: I.  0.64
1974 Wilkinson DS, Tlsty TD. Effects of 5 fluorouridine on ribosomal RNA synthesis and precursor stability Federation Proceedings. 33: II No. 298.  0.64
1974 Wilkinson DS, Tlsty TD. Inhibition of ribosomal RNA maturation by 5 fluorouridine Proceedings of the American Association For Cancer Research. 47.  0.64
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