Richard S. Jope - Publications

1983-2011 Pharmacology University of Alabama, Birmingham, Birmingham, AL, United States 
 2011- Psychiatry and Behavioral Sciences University of Miami, Coral Gables, FL 
Mood disorders, Fragile X syndrome, multiple sclerosis, mechanisms regulating mood and cognition.

246 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Medina-Rodriguez EM, Rice KC, Beurel E, Jope RS. (+)-Naloxone blocks Toll-like receptor 4 to ameliorate deleterious effects of stress on male mouse behaviors. Brain, Behavior, and Immunity. PMID 32860941 DOI: 10.1016/J.Bbi.2020.08.022  0.72
2020 Medina-Rodriguez EM, Cheng Y, Michalek SM, Beurel E, Jope RS. Toll-like receptor 2 (TLR2)-deficiency impairs male mouse recovery from a depression-like state. Brain, Behavior, and Immunity. PMID 32479995 DOI: 10.1016/J.Bbi.2020.05.068  0.72
2018 Beurel E, Lowell JA, Jope RS. Distinct characteristics of hippocampal pathogenic T17 cells in a mouse model of depression. Brain, Behavior, and Immunity. PMID 29698707 DOI: 10.1016/J.Bbi.2018.04.012  0.72
2018 Cheng Y, Desse S, Martinez A, Worthen RJ, Jope RS, Beurel E. TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice. Brain, Behavior, and Immunity. PMID 29452218 DOI: 10.1016/J.Bbi.2018.02.003  0.72
2017 Pardo M, Cheng Y, Velmeshev D, Magistri M, Eldar-Finkelman H, Martinez A, Faghihi MA, Jope RS, Beurel E. Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice. Jci Insight. 2: e91782. PMID 28352664 DOI: 10.1172/Jci.Insight.91782  0.72
2016 Jope RS, Cheng Y, Lowell JA, Worthen RJ, Sitbon YH, Beurel E. Stressed and Inflamed, Can GSK3 Be Blamed? Trends in Biochemical Sciences. PMID 27876551 DOI: 10.1016/J.Tibs.2016.10.009  0.72
2016 Pardo M, Beurel E, Jope RS. Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome. The European Journal of Neuroscience. PMID 27775852 DOI: 10.1111/Ejn.13446  0.72
2016 Grieco SF, Velmeshev D, Magistri M, Eldar-Finkelman H, Faghihi MA, Jope RS, Beurel E. Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-12. PMID 27723376 DOI: 10.1080/15622975.2016.1224927  0.72
2016 Beurel E, Grieco SF, Amadei C, Downey K, Jope RS. Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling. Bipolar Disorders. PMID 27687706 DOI: 10.1111/Bdi.12436  0.72
2016 Grieco SF, Cheng Y, Eldar-Finkelman H, Jope RS, Beurel E. Up-regulation of insulin-like growth factor 2 by ketamine requires glycogen synthase kinase-3 inhibition. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 27542584 DOI: 10.1016/J.Pnpbp.2016.08.008  0.4
2016 Cheng Y, Pardo M, Armini RS, Martinez A, Mouhsine H, Zagury JF, Jope RS, Beurel E. Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. Brain, Behavior, and Immunity. PMID 26772151 DOI: 10.1016/J.Bbi.2015.12.012  1
2016 Pardo M, Abrial E, Jope RS, Beurel E. GSK3β isoform-selective regulation of depression, memory and hippocampal cell proliferation. Genes, Brain, and Behavior. PMID 26749572 DOI: 10.1111/Gbb.12283  1
2015 Cheng Y, Jope RS, Beurel E. A pre-conditioning stress accelerates increases in mouse plasma inflammatory cytokines induced by stress. Bmc Neuroscience. 16: 31. PMID 25947540 DOI: 10.1186/S12868-015-0169-Z  1
2015 Pardo M, King MK, Perez-Costas E, Melendez-Ferro M, Martinez A, Beurel E, Jope RS. Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3. Frontiers in Behavioral Neuroscience. 9: 55. PMID 25788881 DOI: 10.3389/Fnbeh.2015.00055  1
2015 Beurel E, Jope RS. Inflammation and lithium: Clues to mechanisms contributing to suicide-linked traits Translational Psychiatry. 4. PMID 25514751 DOI: 10.1038/Tp.2014.129  1
2015 Beurel E, Grieco SF, Jope RS. Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases. Pharmacology & Therapeutics. 148: 114-31. PMID 25435019 DOI: 10.1016/J.Pharmthera.2014.11.016  1
2014 Beurel E, Harrington LE, Buchser W, Lemmon V, Jope RS. Astrocytes modulate the polarization of CD4+ T cells to Th1 cells. Plos One. 9: e86257. PMID 24489707 DOI: 10.1371/Journal.Pone.0086257  1
2014 Franklin AV, King MK, Palomo V, Martinez A, McMahon LL, Jope RS. Glycogen synthase kinase-3 inhibitors reverse deficits in long-term potentiation and cognition in fragile X mice. Biological Psychiatry. 75: 198-206. PMID 24041505 DOI: 10.1016/J.Biopsych.2013.08.003  1
2014 King MK, Pardo M, Cheng Y, Downey K, Jope RS, Beurel E. Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments. Pharmacology & Therapeutics. 141: 1-12. PMID 23916593 DOI: 10.1016/J.Pharmthera.2013.07.010  1
2013 King MK, Jope RS. Lithium treatment alleviates impaired cognition in a mouse model of fragile X syndrome. Genes, Brain, and Behavior. 12: 723-31. PMID 23941202 DOI: 10.1111/Gbb.12071  1
2013 Beurel E, Kaidanovich-Beilin O, Yeh WI, Song L, Palomo V, Michalek SM, Woodgett JR, Harrington LE, Eldar-Finkelman H, Martinez A, Jope RS. Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3. Journal of Immunology (Baltimore, Md. : 1950). 190: 5000-11. PMID 23606540 DOI: 10.4049/Jimmunol.1203057  1
2013 Yang JY, Deng W, Chen Y, Fan W, Baldwin KM, Jope RS, Wallace DC, Wang PH. Impaired translocation and activation of mitochondrial Akt1 mitigated mitochondrial oxidative phosphorylation Complex V activity in diabetic myocardium. Journal of Molecular and Cellular Cardiology. 59: 167-75. PMID 23500391 DOI: 10.1016/J.Yjmcc.2013.02.016  1
2013 Jope RS, Nemeroff CB. The ups and downs of bipolar disorder research. Biological Psychiatry. 73: 597-9. PMID 23497742 DOI: 10.1016/J.Biopsych.2012.12.014  1
2013 Sun M, Zhou T, Jonasch E, Jope RS. DDX3 regulates DNA damage-induced apoptosis and p53 stabilization. Biochimica Et Biophysica Acta. 1833: 1489-97. PMID 23470959 DOI: 10.1016/J.Bbamcr.2013.02.026  1
2013 Beurel E, Harrington LE, Jope RS. Inflammatory T helper 17 cells promote depression-like behavior in mice. Biological Psychiatry. 73: 622-30. PMID 23174342 DOI: 10.1016/J.Biopsych.2012.09.021  1
2013 Mines MA, Beurel E, Jope RS. Examination of methylphenidate-mediated behavior regulation by glycogen synthase kinase-3 in mice. European Journal of Pharmacology. 698: 252-8. PMID 23099259 DOI: 10.1016/J.Ejphar.2012.10.018  1
2012 Beurel E, Mines MA, Song L, Jope RS. Glycogen synthase kinase-3 levels and phosphorylation undergo large fluctuations in mouse brain during development. Bipolar Disorders. 14: 822-30. PMID 23167932 DOI: 10.1111/Bdi.12023  1
2012 Gulen MF, Bulek K, Xiao H, Yu M, Gao J, Sun L, Beurel E, Kaidanovich-Beilin O, Fox PL, DiCorleto PE, Wang JA, Qin J, Wald DN, Woodgett JR, Jope RS, et al. Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. Immunity. 37: 800-12. PMID 23142783 DOI: 10.1016/J.Immuni.2012.08.019  1
2012 Paul JR, Johnson RL, Jope RS, Gamble KL. Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3. Neuroscience. 226: 1-9. PMID 22986169 DOI: 10.1016/J.Neuroscience.2012.08.047  1
2012 Sun M, Guo X, Qian X, Wang H, Yang C, Brinkman KL, Serrano-Gonzalez M, Jope RS, Zhou B, Engler DA, Zhan M, Wong ST, Fu L, Xu B. Activation of the ATM-Snail pathway promotes breast cancer metastasis. Journal of Molecular Cell Biology. 4: 304-15. PMID 22923499 DOI: 10.1093/Jmcb/Mjs048  1
2012 Kaidanovich-Beilin O, Beaulieu JM, Jope RS, Woodgett JR. Neurological functions of the masterswitch protein kinase - gsk-3. Frontiers in Molecular Neuroscience. 5: 48. PMID 22509152 DOI: 10.3389/Fnmol.2012.00048  1
2012 Mines MA, Jope RS. Brain region differences in regulation of Akt and GSK3 by chronic stimulant administration in mice. Cellular Signalling. 24: 1398-405. PMID 22434044 DOI: 10.1016/J.Cellsig.2012.03.001  1
2012 Polter AM, Yang S, Jope RS, Li X. Functional significance of glycogen synthase kinase-3 regulation by serotonin. Cellular Signalling. 24: 265-71. PMID 21946431 DOI: 10.1016/J.Cellsig.2011.09.009  1
2012 Kaidanovich-Beilin O, Beaulieu JM, Jope RS, Woodgett JR. Neurological functions of the masterswitch protein kinase - Gsk-3 Frontiers in Molecular Neuroscience 1
2011 Mines MA, Jope RS. Glycogen synthase kinase-3: a promising therapeutic target for fragile x syndrome. Frontiers in Molecular Neuroscience. 4: 35. PMID 22053151 DOI: 10.3389/Fnmol.2011.00035  0.6
2011 Mines MA, Beurel E, Jope RS. Regulation of cell survival mechanisms in Alzheimer's disease by glycogen synthase kinase-3. International Journal of Alzheimer's Disease. 2011: 861072. PMID 21629713 DOI: 10.4061/2011/861072  1
2011 Beurel E, Song L, Jope RS. Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice Molecular Psychiatry. 16: 1068-1070. PMID 21502951 DOI: 10.1038/Mp.2011.47  1
2011 Wang H, Brown J, Gu Z, Garcia CA, Liang R, Alard P, Beurel E, Jope RS, Greenway T, Martin M. Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response. Journal of Immunology (Baltimore, Md. : 1950). 186: 5217-26. PMID 21422248 DOI: 10.4049/Jimmunol.1002513  1
2011 Meares GP, Mines MA, Beurel E, Eom TY, Song L, Zmijewska AA, Jope RS. Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells. Experimental Cell Research. 317: 1621-8. PMID 21356208 DOI: 10.1016/J.Yexcr.2011.02.012  1
2011 Sun M, Song L, Zhou T, Gillespie GY, Jope RS. The role of DDX3 in regulating Snail. Biochimica Et Biophysica Acta. 1813: 438-47. PMID 21237216 DOI: 10.1016/J.Bbamcr.2011.01.003  1
2011 Beurel E, Yeh WI, Michalek SM, Harrington LE, Jope RS. Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 1391-8. PMID 21191064 DOI: 10.4049/Jimmunol.1003511  1
2010 Li X, Jope RS. Is glycogen synthase kinase-3 a central modulator in mood regulation? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2143-54. PMID 20668436 DOI: 10.1038/Npp.2010.105  1
2010 Yuskaitis CJ, Beurel E, Jope RS. Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome. Biochimica Et Biophysica Acta. 1802: 1006-12. PMID 20600866 DOI: 10.1016/J.Bbadis.2010.06.015  1
2010 Beurel E, Jope RS. Glycogen synthase kinase-3 regulates inflammatory tolerance in astrocytes Neuroscience. 169: 1063-1070. PMID 20553816 DOI: 10.1016/J.Neuroscience.2010.05.044  1
2010 Polter A, Beurel E, Yang S, Garner R, Song L, Miller CA, Sweatt JD, McMahon L, Bartolucci AA, Li X, Jope RS. Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1761-74. PMID 20357757 DOI: 10.1038/Npp.2010.43  1
2010 Mines MA, Yuskaitis CJ, King MK, Beurel E, Jope RS. GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism. Plos One. 5: e9706. PMID 20300527 DOI: 10.1371/Journal.Pone.0009706  1
2010 Beurel E, Michalek SM, Jope RS. Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3). Trends in Immunology. 31: 24-31. PMID 19836308 DOI: 10.1016/J.It.2009.09.007  1
2010 Yuskaitis CJ, Mines MA, King MK, Sweatt JD, Miller CA, Jope RS. Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome. Biochemical Pharmacology. 79: 632-46. PMID 19799873 DOI: 10.1016/J.Bcp.2009.09.023  1
2010 Sun M, Zhou T, Gillespie Y, Xu B, Jope R. Abstract 2981: Regulation of Snail by DDX3 and ATM in response to DNA damage Cancer Research. 70: 2981-2981. DOI: 10.1158/1538-7445.Am10-2981  0.6
2009 Sun M, Meares G, Song L, Jope RS. XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3. Cellular Signalling. 21: 1857-65. PMID 19698783 DOI: 10.1016/J.Cellsig.2009.08.002  1
2009 Eom TY, Jope RS. Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation. Biological Psychiatry. 66: 494-502. PMID 19520363 DOI: 10.1016/J.Biopsych.2009.04.015  1
2009 Beurel E, Jope RS. Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain. Journal of Neuroinflammation. 6: 9. PMID 19284588 DOI: 10.1186/1742-2094-6-9  1
2009 Eom TY, Jope RS. GSK3 beta N-terminus binding to p53 promotes its acetylation. Molecular Cancer. 8: 14. PMID 19265551 DOI: 10.1186/1476-4598-8-14  1
2009 Beurel E, Jope RS. Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells. Cellular Signalling. 21: 978-85. PMID 19258035 DOI: 10.1016/J.Cellsig.2009.02.019  1
2009 Yuskaitis CJ, Jope RS. Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity. Cellular Signalling. 21: 264-73. PMID 19007880 DOI: 10.1016/J.Cellsig.2008.10.014  1
2009 Min WW, Yuskaitis CJ, Yan Q, Sikorski C, Chen S, Jope RS, Bauchwitz RP. Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential. Neuropharmacology. 56: 463-72. PMID 18952114 DOI: 10.1016/J.Neuropharm.2008.09.017  1
2009 Polter A, Yang S, Zmijewska AA, van Groen T, Paik JH, Depinho RA, Peng SL, Jope RS, Li X. Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. Biological Psychiatry. 65: 150-9. PMID 18823877 DOI: 10.1016/J.Biopsych.2008.08.005  1
2008 Sun M, Song L, Li Y, Zhou T, Jope RS. Identification of an antiapoptotic protein complex at death receptors. Cell Death and Differentiation. 15: 1887-900. PMID 18846110 DOI: 10.1038/Cdd.2008.124  1
2008 De Sarno P, Axtell RC, Raman C, Roth KA, Alessi DR, Jope RS. Lithium prevents and ameliorates experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 181: 338-45. PMID 18566399 DOI: 10.4049/Jimmunol.181.1.338  1
2008 Beurel E, Jope RS. Differential regulation of STAT family members by glycogen synthase kinase-3. The Journal of Biological Chemistry. 283: 21934-44. PMID 18550525 DOI: 10.1074/Jbc.M802481200  1
2008 Meares GP, Zmijewska AA, Jope RS. HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation. Cellular Signalling. 20: 347-58. PMID 18083346 DOI: 10.1016/J.Cellsig.2007.10.032  1
2007 Eom TY, Roth KA, Jope RS. Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3. The Journal of Biological Chemistry. 282: 22856-64. PMID 17548347 DOI: 10.1074/Jbc.M702973200  1
2007 Meares GP, Jope RS. Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis. The Journal of Biological Chemistry. 282: 16989-7001. PMID 17438332 DOI: 10.1074/Jbc.M700610200  1
2007 Mookherjee P, Quintanilla R, Roh MS, Zmijewska AA, Jope RS, Johnson GV. Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death. Journal of Cellular Biochemistry. 102: 196-210. PMID 17340627 DOI: 10.1002/Jcb.21287  1
2007 Jope RS, Yuskaitis CJ, Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochemical Research. 32: 577-95. PMID 16944320 DOI: 10.1007/S11064-006-9128-5  1
2007 Li X, Friedman AB, Zhu W, Wang L, Boswell S, May RS, Davis LL, Jope RS. Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder. Biological Psychiatry. 61: 216-22. PMID 16806104 DOI: 10.1016/J.Biopsych.2006.02.027  1
2006 Clodfelder-Miller BJ, Zmijewska AA, Johnson GV, Jope RS. Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency. Diabetes. 55: 3320-5. PMID 17130475 DOI: 10.2337/Db06-0485  1
2006 Jope RS, Roh MS. Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Current Drug Targets. 7: 1421-34. PMID 17100582 DOI: 10.2174/1389450110607011421  1
2006 Beurel E, Jope RS. The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Progress in Neurobiology. 79: 173-89. PMID 16935409 DOI: 10.1016/J.Pneurobio.2006.07.006  1
2006 Song L, Jope RS. Cellular stress increases RGS2 mRNA and decreases RGS4 mRNA levels in SH-SY5Y cells. Neuroscience Letters. 402: 205-9. PMID 16733081 DOI: 10.1016/J.Neulet.2006.03.023  1
2006 King TD, Song L, Jope RS. AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3. Biochemical Pharmacology. 71: 1637-47. PMID 16620785 DOI: 10.1016/J.Bcp.2006.03.005  1
2006 De Sarno P, Bijur GN, Zmijewska AA, Li X, Jope RS. In vivo regulation of GSK3 phosphorylation by cholinergic and NMDA receptors. Neurobiology of Aging. 27: 413-22. PMID 16464655 DOI: 10.1016/J.Neurobiolaging.2005.03.003  1
2006 Jope RS. Lithium, the Seminal GSK-3 Inhibitor Glycogen Synthase Kinase 3 (Gsk-3) and Its Inhibitors: Drug Discovery and Development. 221-242. DOI: 10.1002/0470052171.ch12  1
2005 Clodfelder-Miller B, De Sarno P, Zmijewska AA, Song L, Jope RS. Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3. The Journal of Biological Chemistry. 280: 39723-31. PMID 16179343 DOI: 10.1074/Jbc.M508824200  1
2005 Martin M, Rehani K, Jope RS, Michalek SM. Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nature Immunology. 6: 777-84. PMID 16007092 DOI: 10.1038/Ni1221  1
2005 King TD, Jope RS. Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress. Neuroreport. 16: 597-601. PMID 15812315 DOI: 10.1097/00001756-200504250-00016  1
2005 De Sarno P, Shestopal SA, Zmijewska AA, Jope RS. Anti-apoptotic effects of muscarinic receptor activation are mediated by Rho kinase. Brain Research. 1041: 112-5. PMID 15804506 DOI: 10.1016/J.Brainres.2005.01.081  1
2005 Roh MS, Eom TY, Zmijewska AA, De Sarno P, Roth KA, Jope RS. Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine. Biological Psychiatry. 57: 278-86. PMID 15691529 DOI: 10.1016/J.Biopsych.2004.10.039  1
2005 Li X, Friedman AB, Roh MS, Jope RS. Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain. Journal of Neurochemistry. 92: 701-4. PMID 15659239 DOI: 10.1111/J.1471-4159.2004.02898.X  1
2004 Zmijewski JW, Jope RS. Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts. Aging Cell. 3: 309-17. PMID 15379854 DOI: 10.1111/J.1474-9728.2004.00117.X  1
2004 Meares GP, Zmijewska AA, Jope RS. Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin. Febs Letters. 574: 181-6. PMID 15358562 DOI: 10.1016/J.Febslet.2004.08.026  1
2004 Song L, Zhou T, Jope RS. Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor. Bmc Neuroscience. 5: 20. PMID 15157283 DOI: 10.1186/1471-2202-5-20  1
2004 Jope RS, Johnson GV. The glamour and gloom of glycogen synthase kinase-3. Trends in Biochemical Sciences. 29: 95-102. PMID 15102436 DOI: 10.1016/J.Tibs.2003.12.004  1
2004 Li X, Zhu W, Roh MS, Friedman AB, Rosborough K, Jope RS. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1426-31. PMID 15039769 DOI: 10.1038/Sj.Npp.1300439  1
2004 Jope RS. Inhibition of glycogen synthase kinase-3: A potential therapeutic target of lithium Clinical Neuroscience Research. 4: 171-179. DOI: 10.1016/J.Cnr.2004.09.009  1
2004 Zmijewski JW, Song L, Jope RS. Stress- and cell cycle-associated regulation of RGS2 mRNA levels Neuroscience Research Communications. 34: 72-81. DOI: 10.1002/Nrc.20000  1
2003 Bijur GN, Jope RS. Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation. Journal of Neurochemistry. 87: 1427-35. PMID 14713298 DOI: 10.1046/J.1471-4159.2003.02113.X  1
2003 Bijur GN, Jope RS. Glycogen synthase kinase-3 beta is highly activated in nuclei and mitochondria. Neuroreport. 14: 2415-9. PMID 14663202 DOI: 10.1097/00001756-200312190-00025  1
2003 Watcharasit P, Bijur GN, Song L, Zhu J, Chen X, Jope RS. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. The Journal of Biological Chemistry. 278: 48872-9. PMID 14523002 DOI: 10.1074/Jbc.M305870200  1
2003 Jope RS. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends in Pharmacological Sciences. 24: 441-3. PMID 12967765 DOI: 10.1016/S0165-6147(03)00206-2  1
2003 Jope RS. Should tobacco ban rule out governments too? Nature. 422: 802. PMID 12712167 DOI: 10.1038/422802B  1
2003 De Sarno P, Shestopal SA, King TD, Zmijewska A, Song L, Jope RS. Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition. The Journal of Biological Chemistry. 278: 11086-93. PMID 12538580 DOI: 10.1074/Jbc.M212157200  1
2002 De Sarno P, Li X, Jope RS. Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology. 43: 1158-64. PMID 12504922 DOI: 10.1016/S0028-3908(02)00215-0  1
2002 Song L, De Sarno P, Jope RS. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. The Journal of Biological Chemistry. 277: 44701-8. PMID 12228224 DOI: 10.1074/Jbc.M206047200  1
2002 Mai L, Jope RS, Li X. BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents. Journal of Neurochemistry. 82: 75-83. PMID 12091467 DOI: 10.1046/J.1471-4159.2002.00939.X  1
2002 Li X, Bijur GN, Jope RS. Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection. Bipolar Disorders. 4: 137-44. PMID 12071511 DOI: 10.1034/J.1399-5618.2002.40201.X  1
2002 Watcharasit P, Bijur GN, Zmijewski JW, Song L, Zmijewska A, Chen X, Johnson GV, Jope RS. Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 99: 7951-5. PMID 12048243 DOI: 10.1073/Pnas.122062299  1
2002 Jope RS, Bijur GN. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Molecular Psychiatry. 7: S35-45. PMID 11986994 DOI: 10.1038/Sj.Mp.4001017  1
2001 Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS. Second messengers regulate RGS2 expression which is targeted to the nucleus Biochimica Et Biophysica Acta - Molecular Cell Research. 1541: 201-211. PMID 11755214 DOI: 10.1016/S0167-4889(01)00144-6  1
2001 King TD, Bijur GN, Jope RS. Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Research. 919: 106-14. PMID 11689167 DOI: 10.1016/S0006-8993(01)03005-0  1
2001 Grimes CA, Jope RS. CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium. Journal of Neurochemistry. 78: 1219-32. PMID 11579131 DOI: 10.1046/J.1471-4159.2001.00495.X  1
2001 Watcharasit P, Tucholski J, Jope RS. Src family kinase involvement in muscarinic receptor-induced tyrosine phosphorylation in differentiated SH-SY5Y cells. Neurochemical Research. 26: 809-16. PMID 11565612 DOI: 10.1023/A:1011612118779  1
2001 Grimes CA, Jope RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Progress in Neurobiology. 65: 391-426. PMID 11527574 DOI: 10.1016/S0301-0082(01)00011-9  1
2001 Bijur GN, Jope RS. Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. The Journal of Biological Chemistry. 276: 37436-42. PMID 11495916 DOI: 10.1074/Jbc.M105725200  1
2001 Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS. Oxidative stress and heat shock stimulate RGS2 expression in 1321N1 astrocytoma cells Archives of Biochemistry and Biophysics. 392: 192-196. PMID 11488592 DOI: 10.1006/Abbi.2001.2430  1
2001 De Sarno P, Lesort M, Bijur GN, Johnson GV, Jope RS. Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1. Brain Research. 903: 226-30. PMID 11382407 DOI: 10.1016/S0006-8993(01)02428-3  1
2001 Song L, Zmijewski JW, Jope RS. RGS2: Regulation of expression and nuclear localization Biochemical and Biophysical Research Communications. 283: 102-106. PMID 11322774 DOI: 10.1006/Bbrc.2001.4742  1
2000 Bijur GN, Jope RS. Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity. Journal of Neurochemistry. 75: 2401-8. PMID 11080191 DOI: 10.1046/J.1471-4159.2000.0752401.X  1
2000 De Sarno P, Bijur GN, Lu R, Davis RE, Jope RS. Alterations in muscarinic receptor-coupled phosphoinositide hydrolysis and AP-1 activation in Alzheimer's disease cybrid cells. Neurobiology of Aging. 21: 31-8. PMID 10794846 DOI: 10.1016/S0197-4580(00)00095-6  1
2000 Jope RS, Zhang L, Song L. Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells Archives of Biochemistry and Biophysics. 376: 365-370. PMID 10775424 DOI: 10.1006/Abbi.2000.1728  1
2000 Bijur GN, De Sarno P, Jope RS. Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium. The Journal of Biological Chemistry. 275: 7583-90. PMID 10713065 DOI: 10.1074/Jbc.275.11.7583  1
2000 Jope RS. Designer labs [5] Science. 287: 1204-1205.  1
1999 Lesort M, Greendorfer A, Stockmeier C, Johnson GVW, Jope RS. Glycogen synthase kinase-3β, β-catenin, and tau in postmortem bipolar brain Journal of Neural Transmission. 106: 1217-1222. PMID 10651115 DOI: 10.1007/S007020050235  1
1999 Zhang L, Jope RS. Oxidative stress differentially modulates phosphorylation of ERK, p38 and CREB induced by NGF or EGF in PC12 cells Neurobiology of Aging. 20: 271-278. PMID 10588574 DOI: 10.1016/S0197-4580(99)00049-4  1
1999 Pacheco MA, Jope RS. Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells Molecular Brain Research. 72: 138-146. PMID 10529472 DOI: 10.1016/S0169-328X(99)00215-6  1
1999 Zhang J, Tucholski J, Lesort M, Jope RS, Johnson GV. Novel bimodal effects of the G-protein tissue transglutaminase on adrenoreceptor signalling. The Biochemical Journal. 343: 541-9. PMID 10527931 DOI: 10.1042/0264-6021:3430541  1
1999 Song L, De Sarno P, Jope RS. Muscarinic receptor stimulation increases regulators of G-protein signaling 2 mRNA levels through a protein kinase C-dependent mechanism Journal of Biological Chemistry. 274: 29689-29693. PMID 10514440 DOI: 10.1074/Jbc.274.42.29689  1
1999 Grimes CA, Jope RS. Cholinergic stimulation of early growth response-1 DNA binding activity requires protein kinase C and mitogen-activated protein kinase kinase activation and is inhibited by sodium valproate in SH-SY5Y cells. Journal of Neurochemistry. 73: 1384-92. PMID 10501181 DOI: 10.1046/J.1471-4159.1999.0731384.X  1
1999 Bijur GN, Davis RE, Jope RS. Rapid activation of heat shock factor-1 DNA binding by H2O2 and modulation by glutathione in human neuroblastoma and Alzheimer's disease cybrid cells. Brain Research. Molecular Brain Research. 71: 69-77. PMID 10407188 DOI: 10.1016/S0169-328X(99)00168-0  1
1999 Jope RS, Song L, Grimes CA, Zhang L. Oxidative stress oppositely modulates protein tyrosine phosphorylation stimulated by muscarinic G protein-coupled and epidermal growth factor receptors. Journal of Neuroscience Research. 55: 329-40. PMID 10348664 DOI: 10.1002/(Sici)1097-4547(19990201)55:3<329::Aid-Jnr8>3.0.Co;2-K  1
1999 Lu R, Song L, Jope RS. Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells Neuroreport. 10: 1123-1125. PMID 10321495 DOI: 10.1097/00001756-199904060-00040  1
1999 Jope RS. Anti-bipolar therapy: Mechanism of action of lithium Molecular Psychiatry. 4: 117-128. PMID 10208444 DOI: 10.1038/Sj.Mp.4000494  1
1999 Jope RS. A bimodal model of the mechanism of action of lithium Molecular Psychiatry. 4: 21-25. PMID 10089004 DOI: 10.1038/Sj.Mp.4000444  1
1999 Zhang L, Jope RS. Muscarinic M3 and epidermal growth factor receptors activate mutually inhibitory signaling cascades in human neuroblastoma SH-SY5Y cells Biochemical and Biophysical Research Communications. 255: 774-777. PMID 10049786 DOI: 10.1006/Bbrc.1999.0273  1
1999 Lesort M, Jope RS, Johnson GVW. Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3β and Fyn tyrosine kinase Journal of Neurochemistry. 72: 576-584. PMID 9930729 DOI: 10.1046/J.1471-4159.1999.0720576.X  1
1999 Zhou T, Song L, Yang P, Wang Z, Lui D, Jope RS. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases Nature Medicine. 5: 42-48. PMID 9883838 DOI: 10.1038/4723  1
1999 Jope RS. Cholinergic muscarinic receptor signaling by the phosphoinositide signal transduction system in Alzheimer's disease Journal of Alzheimer's Disease. 1: 231-247. DOI: 10.3233/Jad-1999-14-505  1
1998 De Sarno P, Jope RS. Phosphoinositide hydrolysis activated by muscarinic or glutamatergic, but not adrenergic, receptors is impaired in apoE-deficient mice and by hydrogen peroxide and peroxynitrite Experimental Neurology. 152: 123-128. PMID 9682019 DOI: 10.1006/Exnr.1998.6825  1
1998 Xie H, Litersky JM, Hartigan JA, Jope RS, Johnson GV. The interrelationship between selective tau phosphorylation and microtubule association. Brain Research. 798: 173-83. PMID 9666118 DOI: 10.1016/S0006-8993(98)00407-7  1
1998 Li X, De Sarno P, Song L, Beckman JS, Jope RS. Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells. The Biochemical Journal. 331: 599-606. PMID 9531503 DOI: 10.1042/Bj3310599  1
1998 Li X, Song L, Jope RS. Glutathione depletion exacerbates impairment by oxidative stress of phosphoinositide hydrolysis, AP-1, and NF-κB activation by cholinergic stimulation Molecular Brain Research. 53: 196-205. PMID 9473671 DOI: 10.1016/S0169-328X(97)00290-8  1
1998 Jope RS, Song L, Grimes CA, Pacheco MA, Dilley GE, Li X, Meltzer HY, Overholser JC, Stockmeier CA. Selective increases in phosphoinositide signaling activity and G protein levels in postmortem brain from subjects with schizophrenia or alcohol dependence. Journal of Neurochemistry. 70: 763-71. PMID 9453572 DOI: 10.1046/J.1471-4159.1998.70020763.X  1
1997 Ordway JM, Tallaksen-Greene S, Gutekunst CA, Bernstein EM, Cearley JA, Wiener HW, Dure LS, Lindsey R, Hersch SM, Jope RS, Albin RL, Detloff PJ. Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse. Cell. 91: 753-63. PMID 9413985 DOI: 10.1016/S0092-8674(00)80464-X  1
1997 Jope RS, Song L. AP-1 and NF-κB stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium Molecular Brain Research. 50: 171-180. PMID 9406932 DOI: 10.1016/S0169-328X(97)00183-6  1
1997 Pacheco MA, Jope RS. Comparison of [3H] phosphatidylinositol and [3H] phosphatidylinositol 4,5-bisphosphate hydrolysis in postmortem human brain membranes and characterization of stimulation by dopamine D1 receptors Journal of Neurochemistry. 69: 639-644. PMID 9231722 DOI: 10.1046/J.1471-4159.1997.69020639.X  1
1997 Li X, Jope RS. Glucocorticoids modulate G-protein α-subunit levels in PC 12 cells Brain Research. 759: 213-220. PMID 9221939 DOI: 10.1016/S0006-8993(97)00256-4  1
1997 Unlap MT, Jope RS. Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cells Neuropsychopharmacology. 17: 12-17. PMID 9194045 DOI: 10.1016/S0893-133X(97)00020-1  1
1997 Unlap MT, Jope RS. Dexamethasone attenuates NF-κB DNA binding activity without inducing IκB levels in rat brain in vivo Molecular Brain Research. 45: 83-89. PMID 9105673 DOI: 10.1016/S0169-328X(96)00240-9  1
1997 Jope RS, Song L, Powers RE. Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain. Neurobiology of Aging. 18: 111-20. PMID 8983039 DOI: 10.1016/S0197-4580(96)00205-9  1
1996 Pacheco MA, Jope RS. Phosphoinositide signaling in human brain Progress in Neurobiology. 50: 255-273. PMID 8971982 DOI: 10.1016/S0301-0082(96)00035-4  1
1996 Li X, Song L, Jope RS. Cholinergic stimulation of AP-1 and NFκB transcription factors is differentially sensitive to oxidative stress in SH-SY5Y neuroblastoma: Relationship to phosphoinositide hydrolysis Journal of Neuroscience. 16: 5914-5922. PMID 8815874 DOI: 10.1523/Jneurosci.16-19-05914.1996  1
1996 Pacheco MA, Stockmeier C, Meltzer HY, Overholser JC, Dilley GE, Jope RS. Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain Brain Research. 723: 37-45. PMID 8813380 DOI: 10.1016/0006-8993(96)00207-7  1
1996 Li X, Greenwood AF, Powers R, Jope RS. Effects of postmortem interval, age, and Alzheimer's disease on G-proteins in human brain. Neurobiology of Aging. 17: 115-22. PMID 8786793 DOI: 10.1016/0197-4580(95)02023-3  1
1996 Jope RS, Song L, Li PP, Young LT, Kish SJ, Pacheco MA, Warsh JJ. The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain Journal of Neurochemistry. 66: 2402-2409. PMID 8632163 DOI: 10.1046/J.1471-4159.1996.66062402.X  1
1996 Li X, Jope RS. [14] Production of G protein α-subunit-specific monoclonal antibodies Methods in Neurosciences. 29: 187-206. DOI: 10.1016/S1043-9471(96)80050-4  1
1995 Williams MB, Jope RS. Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: modulation by lithium Psychopharmacology. 122: 363-368. PMID 8657834 DOI: 10.1007/Bf02246267  1
1995 Greenwood AF, Powers RE, Jope RS. Phosphoinositide hydrolysis, G alpha q, phospholipase C, and protein kinase C in post mortem human brain: effects of post mortem interval, subject age, and Alzheimer's disease. Neuroscience. 69: 125-38. PMID 8637611 DOI: 10.1016/0306-4522(95)00220-D  1
1995 Unlap T, Jope RS. Inhibition of NFkB DNA binding activity by glucocorticoids in rat brain Neuroscience Letters. 198: 41-44. PMID 8570092 DOI: 10.1016/0304-3940(95)11963-W  1
1995 Li X, Mumby SM, Greenwood A, Jope RS. Pertussis toxin-sensitive G protein alpha-subunits: production of monoclonal antibodies and detection of differential increases on differentiation of PC12 and LA-N-5 cells. Journal of Neurochemistry. 64: 1107-17. PMID 7861141 DOI: 10.1046/J.1471-4159.1995.64031107.X  1
1995 Unlap T, Jope RS. Diurnal variation in kainate-induced AP-1 activation in rat brain: influence of glucocorticoids Molecular Brain Research. 28: 193-200. PMID 7723618 DOI: 10.1016/0169-328X(94)00202-P  1
1995 Li X, Jope RS. Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells Journal of Neurochemistry. 65: 2500-2508. PMID 7595544 DOI: 10.1046/J.1471-4159.1995.65062500.X  1
1995 Williams MB, Jope RS. Modulation by inositol of cholinergic-and serotonergic-induced seizures in lithium-treated rats Brain Research. 685: 169-178. PMID 7583243 DOI: 10.1016/0006-8993(95)00395-7  1
1995 Su X, Zhou T, Wang Z, Yang P, Jope RS, Mountz JD. Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis Immunity. 2: 353-362. PMID 7536621 DOI: 10.1016/1074-7613(95)90143-4  1
1994 Jope RS, Song L, Powers R. Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes Journal of Neurochemistry. 62: 180-186. PMID 8263518 DOI: 10.1046/J.1471-4159.1994.62010180.X  1
1994 Jope RS, Williams MB. Lithium and brain signal transduction systems Biochemical Pharmacology. 47: 429-441. PMID 8117309 DOI: 10.1016/0006-2952(94)90172-4  1
1994 Williams MB, Jope RS. Lithium potentiates phosphoinositide-linked 5-HT receptor stimulation in vivo Neuroreport. 5: 1118-1120. PMID 8080969  1
1994 Bubien JK, Jope RS, Warnock DG. G-proteins modulate amiloride-sensitive sodium channels Journal of Biological Chemistry. 269: 17780-17783. PMID 8027031  1
1994 Greenwood AF, Jope RS. Brain G-protein proteolysis by calpain: enhancement by lithium. Brain Research. 636: 320-6. PMID 8012815 DOI: 10.1016/0006-8993(94)91031-6  1
1994 Jope RS, Song L, Powers R. [3H]PtdIns hydrolysis in postmortem human brain membranes is mediated by the G-proteins G(q/11) and phospholipase C-β Biochemical Journal. 304: 655-659. PMID 7999004 DOI: 10.1042/Bj3040655  1
1994 Williams MB, Jope RS. Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine Molecular Brain Research. 25: 80-89. PMID 7984056 DOI: 10.1016/0169-328X(94)90281-X  1
1994 Unlap T, Jope RS. Dexamethasone attenuates kainate-induced AP-1 activation in rat brain Molecular Brain Research. 24: 275-282. PMID 7968367 DOI: 10.1016/0169-328X(94)90140-6  1
1994 Williams MB, Jope RS. Protein Synthesis Inhibitors Attenuate Seizures Induced in Rats by Lithium Plus Pilocarpine Experimental Neurology. 129: 169-173. PMID 7925839 DOI: 10.1006/Exnr.1994.1158  1
1994 Jope RS, Song L, Li X, Powers R. Impaired phosphoinositide hydrolysis in Alzheimer's disease brain Neurobiology of Aging. 15: 221-226. PMID 7838295 DOI: 10.1016/0197-4580(94)90116-3  1
1993 Song L, Baird MS, Jope RS. Hydrolysis of exogenous [3H]phosphatidylcholine by brain membranes and cytosol. Neurochemical Research. 18: 1305-11. PMID 8272195 DOI: 10.1007/Bf00975052  1
1993 Jope RS. Lithium selectively potentiates cholinergic activity in rat brain Progress in Brain Research. 98: 317-322. PMID 8248521 DOI: 10.1016/S0079-6123(08)62414-0  1
1993 Kolasa K, Jope RS. Synergistic activation of phosphoinositide hydrolysis induced in brain slices by norepinephrine and the excitatory amino acid agonist, Trans-ACPD Neuropharmacology. 32: 21-28. PMID 7679209 DOI: 10.1016/0028-3908(93)90125-M  1
1992 Li X, Song L, Kolasa K, Jope RS. Adrenalectomy potentiates immediate early gene expression in rat brain Journal of Neurochemistry. 58: 2330-2333. PMID 1573410 DOI: 10.1111/J.1471-4159.1992.Tb10982.X  1
1992 Song L, Jope RS. Chronic lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions Journal of Neurochemistry. 58: 2200-2206. PMID 1573399 DOI: 10.1111/J.1471-4159.1992.Tb10964.X  1
1992 Johnson GVW, Jope RS. The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration Journal of Neuroscience Research. 33: 505-512. PMID 1484385 DOI: 10.1002/Jnr.490330402  1
1992 Jope RS, Johnson GV. Neurotoxic effects of dietary aluminium Ciba Foundation Symposium. 169: 254-262; discussion . PMID 1337035  1
1992 Williams MB, Li X, Gu X, Jope RS. Modulation of endogenous ADP-ribosylation in rat brain Brain Research. 592: 49-56. PMID 1333343 DOI: 10.1016/0006-8993(92)91657-Z  1
1992 Johnson GV, Watson AL, Lartius R, Uemura E, Jope RS. Dietary aluminum selectively decreases MAP-2 in brains of developing and adult rats. Neurotoxicology. 13: 463-74. PMID 1331920  1
1992 Jope RS, Kolasa K, Song L, Ormandy GC. Seizures selectively impair agonist-stimulated phosphoinositide hydrolysis without affecting protein kinase C activity in rat brain Neurotoxicology. 13: 389-400. PMID 1331919  1
1992 Kolasa K, Jope RS, Baird MS, Johnson GV. Alterations of choline acetyltransferase, phosphoinositide hydrolysis, and cytoskeletal proteins in rat brain in response to colchicine administration. Experimental Brain Research. 89: 496-500. PMID 1322821 DOI: 10.1007/Bf00229873  1
1992 Kolasa K, Song L, Jope RS. Adrenalectomy increases phosphoinositide hydrolysis induced by norepinephrine or excitatory amino acids in rat hippocampal slices Brain Research. 579: 128-134. PMID 1320442 DOI: 10.1016/0006-8993(92)90751-T  1
1992 Jope RS, Song L, Kolasa K. Inositol triphosphate, cyclic AMP, and cyclic GMP in rat brain regions after lithium and seizures Biological Psychiatry. 31: 505-514. PMID 1316177 DOI: 10.1016/0006-3223(92)90261-W  1
1991 Casebolt TL, Jope RS. Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation. Biological Psychiatry. 29: 233-43. PMID 2015330 DOI: 10.1016/0006-3223(91)91285-Y  1
1991 Johnson GVW, Litersky JM, Jope RS. Degradation of microtubule-associated protein 2 and brain spectrin by calpain: A comparative study Journal of Neurochemistry. 56: 1630-1638. PMID 2013758 DOI: 10.1111/J.1471-4159.1991.Tb02061.X  1
1991 Ormandy GC, Jope RS. Pertussis toxin potentiates seizures induced by pilocarpine, kainic acid and N-methyl-d-aspartate Brain Research. 553: 51-57. PMID 1933276 DOI: 10.1016/0006-8993(91)90229-O  1
1991 Ormandy GC, Song L, Jope RS. Analysis of the convulsant-potentiating effects of lithium in rats Experimental Neurology. 111: 356-361. PMID 1847879 DOI: 10.1016/0014-4886(91)90103-J  1
1991 Jope RS, Gu X. Seizures increase acetylcholine and choline concentrations in rat brain regions Neurochemical Research. 16: 1219-1226. PMID 1815138 DOI: 10.1007/Bf00966699  1
1991 Smith RE, Macquarrie RA, Jope RS. Ion chromatographic determination of inositol tris- and tetrakisphosphates in rat brain Journal of Chromatographic Science. 29: 528-531. PMID 1761637 DOI: 10.1093/Chromsci/29.12.528  1
1991 Jope RS, Johnson GV, Baird MS. Seizure-induced protein tyrosine phosphorylation in rat brain regions. Epilepsia. 32: 755-60. PMID 1720736 DOI: 10.1111/J.1528-1157.1991.Tb05530.X  1
1990 Harrell LE, Jope RS, Falgout J, Callaway R, Avery C, Spiers M, Leli D, Morere D, Halsey JH. Biological and neuropsychological characterization of physostigmine responders and nonresponders in Alzheimer's disease. Journal of the American Geriatrics Society. 38: 113-22. PMID 2405043 DOI: 10.1111/J.1532-5415.1990.Tb03471.X  1
1990 Miller JM, Jope RS, Ferraro TN, Hare TA. Brain amino acid concentrations in rats killed by decapitation and microwave irradiation. Journal of Neuroscience Methods. 31: 187-92. PMID 2329838 DOI: 10.1016/0165-0270(90)90109-S  1
1990 Ormandy GC, Li X, Jope RS. Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices Neuropharmacology. 29: 779-782. PMID 2177162 DOI: 10.1016/0028-3908(90)90132-B  1
1990 Johnson GVW, Cogdill KW, Jope RS. Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brain Neurobiology of Aging. 11: 209-216. PMID 2163494 DOI: 10.1016/0197-4580(90)90547-D  1
1990 Ormandy GC, Jope RS. Inhibition of phosphoinositide hydrolysis by the novel neurotoxin β-N-oxalyl-l-α, β-diaminopropionic acid (l-BOAA) Brain Research. 510: 53-57. PMID 2157526 DOI: 10.1016/0006-8993(90)90726-R  1
1990 Casebolt TL, Li XH, Jope RS. Alpha-1 adrenergic receptor binding and adrenergic-stimulated cyclic AMP production in rat cerebral cortex after chronic lithium treatment. Journal of Neural Transmission. General Section. 82: 197-204. PMID 1979002 DOI: 10.1007/Bf01272762  1
1990 Li X, Song L, Jope RS. Modulation of phosphoinositide metabolism in rat brain slices by excitatory amino acids, arachidonic acid, and GABA Neurochemical Research. 15: 725-738. PMID 1975654 DOI: 10.1007/Bf00973654  1
1990 Jope RS, Li X, Ormandy GC, Song L, Williams MB. Reduction of Na+ enhances phosphoinositide hydrolysis and differentiates the stimulatory and inhibitory responses to quisqualate in rat brain slices Brain Research. 536: 251-256. PMID 1964831 DOI: 10.1016/0006-8993(90)90032-7  1
1990 Harrell LE, Jope RS, Falgout J, Callaway R, Avery C, Spiers M, Leli D, Morere D, Halsey JH. Biological and neuropsychological characterization fo physostigmine responders and nonresponders in Alzheimer's disease Journal of the American Geriatrics Society. 38: 133-122.  1
1989 Connor DJ, Harrell LE, Jope RS. Reversal of an aluminum-induced behavioral deficit by administration of deferoxamine. Behavioral Neuroscience. 103: 779-83. PMID 2765182 DOI: 10.1037//0735-7044.103.4.779  1
1989 Smith RE, Macquarrie RA, Jope RS. Determination of inositol phosphates and other anions in rat brain Journal of Chromatographic Science. 27: 491-495. PMID 2760161 DOI: 10.1093/Chromsci/27.8.491  1
1989 Jope RS, Miller JM, Ferraro TN, Hare TA. Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions. Neurochemical Research. 14: 829-34. PMID 2594148 DOI: 10.1007/Bf00964811  1
1989 Simonato M, Jope RS, Bianchi C, Beani L. Lack of excitatory amino acid-induced effects on calcium fluxes measured with45Ca2+ in rat cerebral cortex synaptosomes Neurochemical Research. 14: 677-682. PMID 2571097 DOI: 10.1007/Bf00964878  1
1989 Ormandy GC, Jope RS, Snead OC. Anticonvulsant actions of MK-801 on the lithium-pilocarpine model of status epilepticus in rats Experimental Neurology. 106: 172-180. PMID 2553470 DOI: 10.1016/0014-4886(89)90091-5  1
1989 Johnson GVW, Jope RS, Binder LI. Proteolysis of tau by calpain Biochemical and Biophysical Research Communications. 163: 1505-1511. PMID 2551295 DOI: 10.1016/0006-291X(89)91150-9  1
1989 Li X, Jope RS. Inhibition of receptor-coupled phosphoinositide hydrolysis by sulfur-containing amino acids in rat brain slices Biochemical Pharmacology. 38: 2781-2787. PMID 2550009 DOI: 10.1016/0006-2952(89)90431-0  1
1989 Ormandy GC, Jope RS. Sodium nitroprusside and guanosine 3′,5′-monophosphate (cyclic GMP) inhibit stimulated phosphoinositide hydrolysis in rat cerebral cortical slices Neuroscience Letters. 100: 287-291. PMID 2548129 DOI: 10.1016/0304-3940(89)90700-3  1
1989 Johnson GVW, Li X, Jope RS. Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices Journal of Neurochemistry. 53: 258-263. PMID 2542461 DOI: 10.1111/J.1471-4159.1989.Tb07322.X  1
1989 Jope RS, Xiaohua L. Inhibition of inositol phospholipid synthesis and norepinephrine-stimulated hydrolysis in rat brain slices by excitatory amino acids Biochemical Pharmacology. 38: 589-596. PMID 2537082 DOI: 10.1016/0006-2952(89)90203-7  1
1989 Casebolt TL, Jope RS. Long-term lithium treatment selectively reduces receptor-coupled inositol phospholipid hydrolysis in rat brain. Biological Psychiatry. 25: 329-40. PMID 2536562 DOI: 10.1016/0006-3223(89)90180-7  1
1989 Simonato M, Snead OC, Jope RS. Electroencephalographic effects of intracerebroventricularly administered opioids: Effects of lithium Research Communications in Psychology, Psychiatry and Behavior. 14: 207-223.  1
1988 Johnson GVW, Simonato M, Jope RS. Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: Effects of nerve growth factor, GM1 ganglioside, and vitamin E Neurochemical Research. 13: 685-692. PMID 3173620 DOI: 10.1007/Bf00971589  1
1988 Koenig ML, Jope RS. Effects of lithium on synaptosomal Ca2 + fluxes Psychopharmacology. 96: 267-272. PMID 3148154 DOI: 10.1007/Bf00177573  1
1988 Connor DJ, Jope RS, Harrell LE. Chronic, oral aluminum administration to rats: cognition and cholinergic parameters. Pharmacology, Biochemistry, and Behavior. 31: 467-74. PMID 2854266 DOI: 10.1016/0091-3057(88)90375-9  1
1988 Jope RS. Modulation of phosphoinositide hydrolysis of NaF and aluminum in rat cortical slices Journal of Neurochemistry. 51: 1731-1736. PMID 2846782 DOI: 10.1111/J.1471-4159.1988.Tb01152.X  1
1987 Jope RS, Simonato M, Lally K. Acetylcholine content in rat brain is elevated by status epilepticus induced by lithium and pilocarpine. Journal of Neurochemistry. 49: 944-51. PMID 3612132 DOI: 10.1111/J.1471-4159.1987.Tb00985.X  0.01
1987 Morrisett RA, Jope RS, Snead OC. Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats. Experimental Neurology. 97: 193-200. PMID 3582562 DOI: 10.1016/0014-4886(87)90293-7  1
1987 Koenig ML, Jope RS, Baker HJ, Lally KM. Reduced Ca2+ flux in synaptosomes from cats with GM1 gangliosidosis Brain Research. 424: 169-176. PMID 3121133 DOI: 10.1016/0006-8993(87)91207-8  1
1987 Johnson GV, Jope RS. Aluminum alters cyclic AMP and cyclic GMP levels but not presynaptic cholinergic markers in rat brain in vivo. Brain Research. 403: 1-6. PMID 3030501 DOI: 10.1016/0006-8993(87)90115-6  1
1987 Morrisett RA, Jope RS, Snead OC. Status epilepticus is produced by administration of cholinergic agonists to lithium-treated rats: comparison with kainic acid. Experimental Neurology. 98: 594-605. PMID 2824229 DOI: 10.1016/0014-4886(87)90268-8  1
1987 Jope RS, Casebolt TL, Johnson GV. Modulation of carbachol-stimulated inositol phospholipid hydrolysis in rat cerebral cortex. Neurochemical Research. 12: 693-700. PMID 2819754 DOI: 10.1007/Bf00970524  1
1986 Jope RS, Morrisett RA, Snead OC. Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats. Experimental Neurology. 91: 471-80. PMID 3948956 DOI: 10.1016/0014-4886(86)90045-2  1
1986 Jope RS, Johnson GV. Quinacrine and 2-(4-phenylpiperidino)cyclohexanol (AH5183) inhibit acetylcholine release and synthesis in rat brain slices. Molecular Pharmacology. 29: 45-51. PMID 3945227  0.01
1986 Jope RS, Baker HJ, Connor DJ. Increased acetylcholine synthesis and release in brains of cats with GM1 gangliosidosis. Journal of Neurochemistry. 46: 1567-72. PMID 3083048 DOI: 10.1111/J.1471-4159.1986.Tb01778.X  1
1986 Johnson GV, Jope RS. Aluminum increases cyclic AMP in rat cerebral cortex in vivo. Life Sciences. 39: 1301-5. PMID 3020329 DOI: 10.1016/0024-3205(86)90192-X  1
1986 Jope RS, Morrisett RA. Neurochemical consequences of status epilepticus induced in rats by coadministration of lithium and pilocarpine. Experimental Neurology. 93: 404-14. PMID 3015661 DOI: 10.1016/0014-4886(86)90200-1  1
1985 Baker HJ, Jope RS. Increased metabolism of acetylcholine in brain of cats with Gm1 gangliosidosis Brain Research. 343: 363-365. PMID 3931858 DOI: 10.1016/0006-8993(85)90757-7  1
1984 Jope RS, Jenden DJ, Subramanian CS, Dhopeshwarker GA, Duncan J. Biochemical effects of phosphatidylcholine treatment in rats. Biochemical Pharmacology. 33: 793-8. PMID 6712709 DOI: 10.1016/0006-2952(84)90464-7  1
1984 Jope RS, Wright SM, Jenden DJ. Choline flux in human erythrocytes. Psychopharmacology Bulletin. 20: 674-80. PMID 6494393  1
1984 Ringdahl B, Jope RS, Jenden DJ. Inhibition of high affinity choline transport by stereoisomers of some 3-quinuclidinol derivatives. Biochemical Pharmacology. 33: 2819-22. PMID 6466391 DOI: 10.1016/0006-2952(84)90703-2  1
1983 Kang-Lee YA, McKee RW, Wright SM, Swendseid ME, Jenden DJ, Jope RS. Metabolic effects of nicotinamide administration in rats. The Journal of Nutrition. 113: 215-21. PMID 6218261 DOI: 10.1093/Jn/113.2.215  1
1982 Diamond JM, Meier K, Gosenfeld LF, Jope RS, Jenden DJ, Wright SM. Recovery of erythrocyte Li+/Na+ countertransport and choline transport from lithium therapy. Journal of Psychiatric Research. 17: 385-93. PMID 7187781 DOI: 10.1016/0022-3956(82)90043-7  1
1982 Jope RS, Domino EF, Mathews BN, Sitaram N, Jenden DJ, Ortez A. Free and bound choline blood levels after phosphatidylcholine. Clinical Pharmacology and Therapeutics. 31: 483-7. PMID 7060329 DOI: 10.1038/Clpt.1982.64  1
1982 Jope RS. Effects of phosphatidylcholine administration to rats on choline in blood and choline and acetylcholine in brain. The Journal of Pharmacology and Experimental Therapeutics. 220: 322-8. PMID 7057393  0.01
1981 Jope RS, Jenden DJ. Effects of acute ethanol treatment on cholinergic function in rats. Substance and Alcohol Actions/Misuse. 2: 15-23. PMID 7302799  1
1981 Jope RS. Acetylcholine turnover and compartmentation in rat brain synaptosomes. Journal of Neurochemistry. 36: 1712-21. PMID 7241130 DOI: 10.1111/J.1471-4159.1981.Tb00423.X  0.01
1980 Jope RS, Jenden DJ. The utilization of choline and acetyl coenzyme A for the synthesis of acetylcholine. Journal of Neurochemistry. 35: 318-25. PMID 7452263 DOI: 10.1111/J.1471-4159.1980.Tb06267.X  1
1980 Jenden DJ, Jope RS, Fraser SL. A mechanism for the accumulation of choline in erythrocytes during treatment with lithium. Communications in Psychopharmacology. 4: 339-44. PMID 7333091  1
1980 Jope RS, Jenden DJ, Ehrlich BE, Diamond JM, Gosenfeld LF. Erythrocyte choline concentrations are elevated in manic patients. Proceedings of the National Academy of Sciences of the United States of America. 77: 6144-6. PMID 6934541 DOI: 10.1073/Pnas.77.10.6144  1
1979 Jope RS, Jenden DJ. Dimethylaminoethanol (deanol) metabolism in rat brain and its effect on acetylcholine synthesis. The Journal of Pharmacology and Experimental Therapeutics. 211: 472-9. PMID 512912  1
1979 Jope R. Effects of lithium treatment in vitro and in vivo on acetylcholine metabolism in rat brain. Journal of Neurochemistry. 33: 487-95. PMID 469539 DOI: 10.1111/J.1471-4159.1979.Tb05179.X  0.72
1979 Jope RS, Jenden DJ. Choline and phospholipid metabolism and the synthesis of acetylcholine in rat brain. Journal of Neuroscience Research. 4: 69-82. PMID 423317 DOI: 10.1002/Jnr.490040110  1
1979 Jope RS. High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis. Brain Research. 180: 313-44. PMID 394816 DOI: 10.1016/0165-0173(79)90009-2  0.01
1979 Russell RW, Carson VG, Jope RS, Booth RA, Macri J. Development of behavioral tolerance: a search for subcellular mechanisms. Psychopharmacology. 66: 155-8. PMID 119257 DOI: 10.1007/Bf00427623  1
1978 Weiler MH, Jope RS, Jenden DJ. Effect of pretreatment under various cationic conditions on acetylcholine content and choline transport in rat whole brain synaptosomes. Journal of Neurochemistry. 31: 789-96. PMID 702147 DOI: 10.1111/J.1471-4159.1978.Tb00112.X  1
1978 Jope RS, Jenden DJ, Ehrlich BE, Diamond JM. Choline accumulates in erythrocytes during lithium therapy. The New England Journal of Medicine. 299: 833-4. PMID 692570 DOI: 10.1056/Nejm197810122991514  1
1978 Jope RS. Conditioned avoidance response and acetylcholine and choline levels in rat brain. Journal of Neurochemistry. 30: 1625-6. PMID 671007 DOI: 10.1111/J.1471-4159.1978.Tb10507.X  0.01
1978 Jope RS, Weiler MH, Jenden DJ. Regulation of acetylcholine synthesis: control of choline transport and acetylation in synaptosomes. Journal of Neurochemistry. 30: 949-54. PMID 660198 DOI: 10.1111/J.1471-4159.1978.Tb12386.X  1
1977 Jope RS, Jenden DJ. Synaptosomal transport and acetylation of choline. Life Sciences. 20: 1389-92. PMID 853870 DOI: 10.1016/0024-3205(77)90366-6  1
1976 Jenden DJ, Jope RS, Weiler MH. Regulation of acetylcholine synthesis: does cytoplasmic acetylcholine control high affinity choline uptake? Science (New York, N.Y.). 194: 635-7. PMID 982031 DOI: 10.1126/Science.982031  1
1976 Jope R, Blass JP. The regulation of pyruvate dehydrogenase in brain in vivo. Journal of Neurochemistry. 26: 709-14. PMID 965963 DOI: 10.1111/J.1471-4159.1976.Tb04440.X-I1  1
1975 Gibson GE, Jope R, Blass JP. Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces. The Biochemical Journal. 148: 17-23. PMID 1156396 DOI: 10.1042/Bj1480017  1
1975 Jope R, Blass JP. A comparison of the regulation of pyruvate dehydrogenase in mitochondria from rat brain and liver. The Biochemical Journal. 150: 397-403. PMID 174544 DOI: 10.1042/Bj1500397  1
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