| Year |
Citation |
Score |
| 2023 |
Chen C, Hamza I. Notes from the Underground: Heme Homeostasis in . Biomolecules. 13. PMID 37509184 DOI: 10.3390/biom13071149 |
0.659 |
|
| 2022 |
Sun F, Zhao Z, Willoughby MM, Shen S, Zhou Y, Shao Y, Kang J, Chen Y, Chen M, Yuan X, Hamza I, Reddi AR, Chen C. HRG-9 homologues regulate haem trafficking from haem-enriched compartments. Nature. 610: 768-774. PMID 36261532 DOI: 10.1038/s41586-022-05347-z |
0.624 |
|
| 2022 |
Dutt S, Hamza I, Bartnikas TB. Molecular Mechanisms of Iron and Heme Metabolism. Annual Review of Nutrition. PMID 35508203 DOI: 10.1146/annurev-nutr-062320-112625 |
0.458 |
|
| 2021 |
Hanna DA, Moore CM, Liu L, Yuan X, Dominic IM, Fleischhacker AS, Hamza I, Ragsdale SW, Reddi AR. Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells. The Journal of Biological Chemistry. 101549. PMID 34973332 DOI: 10.1016/j.jbc.2021.101549 |
0.371 |
|
| 2020 |
Simmons WR, Wain L, Toker J, Jagadeesh J, Garrett LJ, Pek RH, Hamza I, Bodine DM. Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals. Frontiers in Genome Editing. 2: 8. PMID 34713217 DOI: 10.3389/fgeed.2020.00008 |
0.416 |
|
| 2020 |
Chambers IG, Willoughby MM, Hamza I, Reddi AR. One ring to bring them all and in the darkness bind them: The Trafficking of Heme without Deliverers. Biochimica Et Biophysica Acta. Molecular Cell Research. 118881. PMID 33022276 DOI: 10.1016/j.bbamcr.2020.118881 |
0.354 |
|
| 2020 |
Bergmann A, Floyd K, Key M, Dameron C, Rees KC, Thornton LB, Whitehead DC, Hamza I, Dou Z. Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection. Plos Pathogens. 16: e1008499. PMID 32407406 DOI: 10.1371/Journal.Ppat.1008499 |
0.475 |
|
| 2020 |
Laranjeira-Silva MF, Hamza I, Pérez-Victoria JM. Iron and Heme Metabolism at the Leishmania-Host Interface. Trends in Parasitology. PMID 32005611 DOI: 10.1016/J.Pt.2019.12.010 |
0.487 |
|
| 2020 |
Simmons WR, Wain L, Toker J, Jagadeesh J, Garrett LJ, Pek RH, Hamza I, Bodine DM. Normal Iron Homeostasis Requires the Transporter SLC48A1 for Efficient Heme-Iron Recycling in Mammals Frontiers in Genome Editing. 2. DOI: 10.3389/fgeed.2020.00008 |
0.438 |
|
| 2019 |
Pek RH, Yuan X, Rietzschel N, Zhang J, Jackson L, Nishibori E, Ribeiro A, Simmons W, Jagadeesh J, Sugimoto H, Alam MZ, Garrett L, Haldar M, Ralle M, Phillips JD, ... ... Hamza I, et al. Hemozoin produced by mammals confers heme tolerance. Elife. 8. PMID 31571584 DOI: 10.7554/Elife.49503 |
0.55 |
|
| 2018 |
Zhang J, Hamza I. Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis. Molecular Genetics and Metabolism. PMID 30626549 DOI: 10.1016/J.Ymgme.2018.12.007 |
0.499 |
|
| 2018 |
Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H. Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Communications Biology. 1: 120. PMID 30272000 DOI: 10.1038/s42003-018-0121-8 |
0.417 |
|
| 2018 |
Zhang J, Chambers I, Yun S, Phillips J, Krause M, Hamza I. Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney. Plos Genetics. 14: e1007665. PMID 30248094 DOI: 10.1371/Journal.Pgen.1007665 |
0.55 |
|
| 2018 |
Laranjeira-Silva MF, Wang W, Samuel TK, Maeda FY, Michailowsky V, Hamza I, Liu Z, Andrews NW. A MFS-like plasma membrane transporter required for Leishmania virulence protects the parasites from iron toxicity. Plos Pathogens. 14: e1007140. PMID 29906288 DOI: 10.1371/Journal.Ppat.1007140 |
0.538 |
|
| 2018 |
Yuan X, Hamza I. Cys links heme: Stereo-orientation of heme transfer in cytochrome c biogenesis. Journal of Molecular Biology. PMID 29510174 DOI: 10.1016/J.Jmb.2018.02.021 |
0.339 |
|
| 2018 |
Chen AJ, Yuan X, Li J, Dong P, Hamza I, Cheng JX. Label-free Imaging of Heme Dynamics in Living Organisms by Transient Absorption Microscopy. Analytical Chemistry. PMID 29401392 DOI: 10.1021/Acs.Analchem.7B05046 |
0.396 |
|
| 2017 |
Gouveia Z, Carlos AR, Yuan X, Aires-da-Silva F, Stocker R, J Maghzal G, Leal SS, Gomes CM, Todorovic S, Iranzo O, Ramos S, Santos AC, Hamza I, Gonçalves J, Soares MP. Characterization of Plasma Labile Heme in Hemolytic Conditions. The Febs Journal. PMID 28783254 DOI: 10.1111/Febs.14192 |
0.388 |
|
| 2017 |
Staroń R, Lipiński P, Lenartowicz M, Bednarz A, Gajowiak A, Smuda E, Krzeptowski W, Pieszka M, Korolonek T, Hamza I, Swinkels DW, Van Swelm RPL, Starzyński RR. Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption. Plos One. 12: e0181117. PMID 28704474 DOI: 10.1371/Journal.Pone.0181117 |
0.529 |
|
| 2017 |
Sinclair J, Pinter K, Samuel T, Beardsley S, Yuan X, Zhang J, Meng K, Yun S, Krause M, Hamza I. Inter-organ signalling by HRG-7 promotes systemic haem homeostasis. Nature Cell Biology. PMID 28581477 DOI: 10.1038/Ncb3539 |
0.408 |
|
| 2016 |
Yuan X, Rietzschel N, Kwon H, Walter Nuno AB, Hanna DA, Phillips JD, Raven EL, Reddi AR, Hamza I. Regulation of intracellular heme trafficking revealed by subcellular reporters. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528661 DOI: 10.1073/Pnas.1609865113 |
0.521 |
|
| 2016 |
Luck AN, Yuan X, Voronin D, Slatko BE, Hamza I, Foster JM. Heme acquisition in the parasitic filarial nematode Brugia malayi. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27363426 DOI: 10.1096/Fj.201600603R |
0.487 |
|
| 2016 |
Reddi AR, Hamza I. Heme Mobilization in Animals: A Metallolipid's Journey. Accounts of Chemical Research. PMID 27254265 DOI: 10.1021/Acs.Accounts.5B00553 |
0.548 |
|
| 2016 |
Hanna DA, Harvey RM, Martinez-Guzman O, Yuan X, Chandrasekharan B, Raju G, Outten FW, Hamza I, Reddi AR. Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247412 DOI: 10.1073/Pnas.1523802113 |
0.392 |
|
| 2016 |
Soares MP, Hamza I. Macrophages and Iron Metabolism. Immunity. 44: 492-504. PMID 26982356 DOI: 10.1016/J.Immuni.2016.02.016 |
0.507 |
|
| 2015 |
Marciano O, Moskovitz Y, Hamza I, Ruthstein S. Histidine residues are important for preserving the structure and heme binding to the C. elegans HRG-3 heme-trafficking protein. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 1253-61. PMID 26531103 DOI: 10.1007/S00775-015-1304-0 |
0.377 |
|
| 2015 |
Renberg RL, Yuan X, Samuel TK, Miguel DC, Hamza I, Andrews NW, Flannery AR. The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis. Plos Neglected Tropical Diseases. 9: e0003804. PMID 26001191 DOI: 10.1371/Journal.Pntd.0003804 |
0.465 |
|
| 2015 |
Korolnek T, Hamza I. Macrophages and iron trafficking at the birth and death of red cells. Blood. 125: 2893-2897. PMID 25778532 DOI: 10.1182/Blood-2014-12-567776 |
0.478 |
|
| 2015 |
Sinclair J, Hamza I. Lessons from bloodless worms: heme homeostasis in C. elegans. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 28: 481-9. PMID 25724951 DOI: 10.1007/S10534-015-9841-0 |
0.558 |
|
| 2014 |
Korolnek T, Hamza I. Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism. Frontiers in Pharmacology. 5: 126. PMID 24926267 DOI: 10.3389/Fphar.2014.00126 |
0.59 |
|
| 2014 |
Korolnek T, Zhang J, Beardsley S, Scheffer GL, Hamza I. Control of metazoan heme homeostasis by a conserved multidrug resistance protein. Cell Metabolism. 19: 1008-19. PMID 24836561 DOI: 10.1016/J.Cmet.2014.03.030 |
0.509 |
|
| 2013 |
Yuan X, Fleming MD, Hamza I. Heme transport and erythropoiesis. Current Opinion in Chemical Biology. 17: 204-11. PMID 23415705 DOI: 10.1016/J.Cbpa.2013.01.010 |
0.503 |
|
| 2013 |
White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I. HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. Cell Metabolism. 17: 261-70. PMID 23395172 DOI: 10.1016/J.Cmet.2013.01.005 |
0.549 |
|
| 2013 |
Huynh C, Yuan X, Miguel DC, Renberg RL, Protchenko O, Philpott CC, Hamza I, Andrews NW. Heme deprivation increases LHR1 expression and promotes uptake of the heme analog ZnMP by L. amazonensis promastigotes. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1002795.G002 |
0.314 |
|
| 2013 |
Hamza I. Hematology from the Ground Up: Lessons from C. elegans Blood. 122. DOI: 10.1182/Blood.V122.21.Sci-16.Sci-16 |
0.568 |
|
| 2012 |
Fleming MD, Hamza I. Mitochondrial heme: an exit strategy at last. The Journal of Clinical Investigation. 122: 4328-30. PMID 23187133 DOI: 10.1172/Jci66607 |
0.515 |
|
| 2012 |
De Domenico I, Lo E, Yang B, Korolnek T, Hamza I, Ward DM, Kaplan J. Retraction notice to: The role of ubiquitination in hepcidin- independent and hepcidin-dependent degradation of ferroportin (Cell Metabolism (2011) 14, (635-646) DOI: 10.1016/j.cmet.2011.09.008) Cell Metabolism. 15: 927. PMID 22866335 DOI: 10.1016/J.Cmet.2012.04.017 |
0.351 |
|
| 2012 |
Huynh C, Yuan X, Miguel DC, Renberg RL, Protchenko O, Philpott CC, Hamza I, Andrews NW. Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1. Plos Pathogens. 8: e1002795. PMID 22807677 DOI: 10.1371/Journal.Ppat.1002795 |
0.502 |
|
| 2012 |
Hamza I, Dailey HA. One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans. Biochimica Et Biophysica Acta. 1823: 1617-32. PMID 22575458 DOI: 10.1016/J.Bbamcr.2012.04.009 |
0.391 |
|
| 2012 |
Chen C, Samuel TK, Krause M, Dailey HA, Hamza I. Heme utilization in the Caenorhabditis elegans hypodermal cells is facilitated by heme-responsive gene-2. The Journal of Biological Chemistry. 287: 9601-12. PMID 22303006 DOI: 10.1074/Jbc.M111.307694 |
0.674 |
|
| 2012 |
Yuan X, Protchenko O, Philpott CC, Hamza I. Topologically conserved residues direct heme transport in HRG-1-related proteins. The Journal of Biological Chemistry. 287: 4914-24. PMID 22174408 DOI: 10.1074/Jbc.M111.326785 |
0.498 |
|
| 2011 |
De Domenico I, Lo E, Yang B, Korolnek T, Hamza I, Ward DM, Kaplan J. The role of ubiquitination in hepcidin-independent and hepcidin-dependent degradation of ferroportin. Cell Metabolism. 14: 635-46. PMID 22019085 DOI: 10.1016/J.Cmet.2011.09.008 |
0.535 |
|
| 2011 |
Chen C, Samuel TK, Sinclair J, Dailey HA, Hamza I. An intercellular heme-trafficking protein delivers maternal heme to the embryo during development in C. elegans. Cell. 145: 720-31. PMID 21620137 DOI: 10.1016/J.Cell.2011.04.025 |
0.645 |
|
| 2010 |
Sinclair J, Hamza I. A novel heme-responsive element mediates transcriptional regulation in Caenorhabditis elegans. The Journal of Biological Chemistry. 285: 39536-43. PMID 20938051 DOI: 10.1074/Jbc.M110.167619 |
0.462 |
|
| 2010 |
Severance S, Rajagopal A, Rao AU, Cerqueira GC, Mitreva M, El-Sayed NM, Krause M, Hamza I. Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans. Plos Genetics. 6: e1001044. PMID 20686661 DOI: 10.1371/Journal.Pgen.1001044 |
0.64 |
|
| 2010 |
Schultz IJ, Chen C, Paw BH, Hamza I. Iron and porphyrin trafficking in heme biogenesis. The Journal of Biological Chemistry. 285: 26753-9. PMID 20522548 DOI: 10.1074/Jbc.R110.119503 |
0.669 |
|
| 2010 |
Ihrig J, Hausmann A, Hain A, Richter N, Hamza I, Lill R, Mühlenhoff U. Iron regulation through the back door: iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiae. Eukaryotic Cell. 9: 460-71. PMID 20008079 DOI: 10.1128/Ec.00213-09 |
0.511 |
|
| 2009 |
Severance S, Hamza I. Trafficking of heme and porphyrins in metazoa. Chemical Reviews. 109: 4596-616. PMID 19764719 DOI: 10.1021/Cr9001116 |
0.586 |
|
| 2008 |
Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature. 453: 1127-31. PMID 18418376 DOI: 10.1038/Nature06934 |
0.651 |
|
| 2007 |
Nass R, Hamza I. The nematode C. elegans as an animal model to explore toxicology in vivo: solid and axenic growth culture conditions and compound exposure parameters. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit1.9. PMID 20922756 DOI: 10.1002/0471140856.Tx0109S31 |
0.347 |
|
| 2006 |
Hamza I. Intracellular trafficking of porphyrins. Acs Chemical Biology. 1: 627-9. PMID 17168567 DOI: 10.1021/Cb600442B |
0.427 |
|
| 2006 |
Held MR, Bungiro RD, Harrison LM, Hamza I, Cappello M. Dietary iron content mediates hookworm pathogenesis in vivo. Infection and Immunity. 74: 289-95. PMID 16368983 DOI: 10.1128/Iai.74.1.289-295.2006 |
0.45 |
|
| 2005 |
Rao AU, Carta LK, Lesuisse E, Hamza I. Lack of heme synthesis in a free-living eukaryote. Proceedings of the National Academy of Sciences of the United States of America. 102: 4270-5. PMID 15767563 DOI: 10.1073/Pnas.0500877102 |
0.56 |
|
| 2003 |
Hamza I, Prohaska J, Gitlin JD. Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase. Proceedings of the National Academy of Sciences of the United States of America. 100: 1215-20. PMID 12538877 DOI: 10.1073/Pnas.0336230100 |
0.42 |
|
| 2002 |
Hamza I, Gitlin JD. Copper chaperones for cytochrome c oxidase and human disease. Journal of Bioenergetics and Biomembranes. 34: 381-8. PMID 12539965 DOI: 10.1023/A:1021254104012 |
0.439 |
|
| 2001 |
Hamza I, Faisst A, Prohaska J, Chen J, Gruss P, Gitlin JD. The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 98: 6848-52. PMID 11391006 DOI: 10.1073/Pnas.111058498 |
0.402 |
|
| 2000 |
Hamza I, Qi Z, King ND, O'Brian MR. Fur-independent regulation of iron metabolism by Irr in Bradyrhizobium japonicum. Microbiology (Reading, England). 146: 669-76. PMID 10746770 DOI: 10.1099/00221287-146-3-669 |
0.52 |
|
| 2000 |
Hamza I, Klomp LW, Gaedigk R, White RA, Gitlin JD. Structure, expression, and chromosomal localization of the mouse Atox1 gene. Genomics. 63: 294-7. PMID 10673341 DOI: 10.1006/Geno.1999.6046 |
0.394 |
|
| 1999 |
Hamza I, Schaefer M, Klomp LW, Gitlin JD. Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 96: 13363-8. PMID 10557326 DOI: 10.1073/Pnas.96.23.13363 |
0.392 |
|
| 1999 |
Qi Z, Hamza I, O'Brian MR. Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 13056-61. PMID 10557272 DOI: 10.1073/Pnas.96.23.13056 |
0.549 |
|
| 1999 |
Hamza I, Hassett R, O'Brian MR. Identification of a functional fur gene in Bradyrhizobium japonicum. Journal of Bacteriology. 181: 5843-6. PMID 10482529 DOI: 10.1128/Jb.181.18.5843-5846.1999 |
0.516 |
|
| 1998 |
Hamza I, Chauhan S, Hassett R, O'Brian MR. The bacterial irr protein is required for coordination of heme biosynthesis with iron availability. The Journal of Biological Chemistry. 273: 21669-74. PMID 9705301 DOI: 10.1074/Jbc.273.34.21669 |
0.543 |
|
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