Irwin H. Gelman - Publications

Roswell Park - Cellular and Molecular Biology State University of New York, Buffalo, Buffalo, NY, United States 
Cell Biology

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Muramatsu M, Akakura S, Gao L, Peresie J, Balderman B, Gelman IH. SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk. Oncotarget. 9: 33515-33527. PMID 30323895 DOI: 10.18632/oncotarget.26067  0.56
2018 Smolinski MP, Bu Y, Clements J, Gelman IH, Hegab T, Cutler DL, Fang JWS, Fetterly G, Kwan R, Barnett A, Lau JYN, Hangauer DG. Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361). Journal of Medicinal Chemistry. PMID 29617135 DOI: 10.1021/acs.jmedchem.8b00164  0.96
2017 Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman IH. SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Oncotarget. 8: 70281-70298. PMID 29050279 DOI: 10.18632/oncotarget.20092  0.56
2016 Chattopadhyay I, Wang J, Qin M, Gao L, Holtz R, Vessella RL, Leach RW, Gelman IH. Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures. Oncotarget. PMID 28055971 DOI: 10.18632/oncotarget.14401  0.56
2015 Dwyer SF, Gao L, Gelman IH. Identification of novel focal adhesion kinase substrates: role for FAK in NFκB signaling. International Journal of Biological Sciences. 11: 404-10. PMID 25798060 DOI: 10.7150/ijbs.10273  0.56
2014 Ko HK, Guo LW, Su B, Gao L, Gelman IH. Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge. Plos One. 9: e111534. PMID 25356636 DOI: 10.1371/journal.pone.0111534  1
2014 Cha JH, Wee HJ, Seo JH, Ahn BJ, Park JH, Yang JM, Lee SW, Lee OH, Lee HJ, Gelman IH, Arai K, Lo EH, Kim KW. Prompt meningeal reconstruction mediated by oxygen-sensitive AKAP12 scaffolding protein after central nervous system injury. Nature Communications. 5: 4952. PMID 25229625 DOI: 10.1038/ncomms5952  1
2014 Gelman IH, Peresie J, Eng KH, Foster BA. Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer. Molecular Cancer Research : McR. 12: 1470-9. PMID 25053806 DOI: 10.1158/1541-7786.MCR-13-0490-T  1
2014 Su B, Gao L, Baranowski C, Gillard B, Wang J, Ransom R, Ko HK, Gelman IH. A genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer. Plos One. 9: e101411. PMID 24983969 DOI: 10.1371/journal.pone.0101411  1
2014 Cha JH, Wee HJ, Seo JH, Ahn BJ, Park JH, Yang JM, Lee SW, Kim EH, Lee OH, Heo JH, Lee HJ, Gelman IH, Arai K, Lo EH, Kim KW. AKAP12 mediates barrier functions of fibrotic scars during CNS repair. Plos One. 9: e94695. PMID 24760034 DOI: 10.1371/journal.pone.0094695  1
2014 Ko HK, Akakura S, Peresie J, Goodrich DW, Foster BA, Gelman IH. A transgenic mouse model for early prostate metastasis to lymph nodes. Cancer Research. 74: 945-53. PMID 24492704 DOI: 10.1158/0008-5472.CAN-13-1157  1
2014 Schulte K, Berger K, Boor P, Jirak P, Gelman IH, Arkill KP, Neal CR, Kriz W, Floege J, Smeets B, Moeller MJ. Origin of parietal podocytes in atubular glomeruli mapped by lineage tracing. Journal of the American Society of Nephrology : Jasn. 25: 129-41. PMID 24071005 DOI: 10.1681/ASN.2013040376  1
2013 Su B, Gillard B, Gao L, Eng KH, Gelman IH. Src controls castration recurrence of CWR22 prostate cancer xenografts. Cancer Medicine. 2: 784-92. PMID 24403252 DOI: 10.1002/cam4.144  1
2013 Smeets B, Boor P, Dijkman H, Sharma SV, Jirak P, Mooren F, Berger K, Bornemann J, Gelman IH, Floege J, van der Vlag J, Wetzels JF, Moeller MJ. Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration. The Journal of Pathology. 229: 645-59. PMID 23124355 DOI: 10.1002/path.4125  1
2013 Liu X, Yang N, Figel SA, Wilson KE, Morrison CD, Gelman IH, Zhang J. PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene. 32: 1266-73. PMID 22525271 DOI: 10.1038/onc.2012.147  1
2012 Havekes R, Canton DA, Park AJ, Huang T, Nie T, Day JP, Guercio LA, Grimes Q, Luczak V, Gelman IH, Baillie GS, Scott JD, Abel T. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18137-49. PMID 23238728 DOI: 10.1523/JNEUROSCI.3612-12.2012  1
2012 Golubovskaya VM, Figel S, Ho BT, Johnson CP, Yemma M, Huang G, Zheng M, Nyberg C, Magis A, Ostrov DA, Gelman IH, Cance WG. A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo. Carcinogenesis. 33: 1004-13. PMID 22402131 DOI: 10.1093/carcin/bgs120  1
2011 Guo LW, Gao L, Rothschild J, Su B, Gelman IH. Control of protein kinase C activity, phorbol ester-induced cytoskeletal remodeling, and cell survival signals by the scaffolding protein SSeCKS/GRAVIN/AKAP12 Journal of Biological Chemistry. 286: 38356-38366. PMID 21903576 DOI: 10.1074/jbc.M111.258830  1
2011 Streb JW, Long X, Lee TH, Sun Q, Kitchen CM, Georger MA, Slivano OJ, Blaner WS, Carr DW, Gelman IH, Miano JM. Retinoid-induced expression and activity of an immediate early tumor suppressor gene in vascular smooth muscle cells. Plos One. 6: e18538. PMID 21483686 DOI: 10.1371/journal.pone.0018538  1
2011 Figel S, Gelman IH. Focal adhesion kinase controls prostate cancer progression via intrinsic kinase and scaffolding functions. Anti-Cancer Agents in Medicinal Chemistry. 11: 607-16. PMID 21355844  1
2011 Akakura S, Bouchard R, Bshara W, Morrison C, Gelman IH. Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation. International Journal of Cancer. Journal International Du Cancer. 129: 2025-31. PMID 21128249 DOI: 10.1002/ijc.25828  1
2011 Bu Y, Gao L, Gelman IH. Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src. International Journal of Cancer. Journal International Du Cancer. 128: 1836-42. PMID 20568114 DOI: 10.1002/ijc.25524  0.96
2010 Gelman IH, Sudol M. Introduction: hanafusa memorial issue, part 2. Genes & Cancer. 1: 1163. PMID 21785489 DOI: 10.1177/1947601911407630  1
2010 Gelman IH, Sudol M. Introduction: hanafusa memorial issue. Genes & Cancer. 1: 1088. PMID 21785488 DOI: 10.1177/1947601911401912  1
2010 Akakura S, Nochajski P, Gao L, Sotomayor P, Matsui S, Gelman IH. Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12. Cell Cycle (Georgetown, Tex.). 9: 4656-65. PMID 21099353  0.56
2010 Su B, Bu Y, Engelberg D, Gelman IH. SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. The Journal of Biological Chemistry. 285: 4578-86. PMID 20018890 DOI: 10.1074/jbc.M109.073494  0.96
2009 Sachdev S, Bu Y, Gelman IH. Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. Bmc Cancer. 9: 12. PMID 19138410 DOI: 10.1186/1471-2407-9-12  0.96
2007 Bu Y, Gelman IH. v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. The Journal of Biological Chemistry. 282: 26725-39. PMID 17626016 DOI: 10.1074/jbc.M702885200  1
2006 Su B, Zheng Q, Vaughan MM, Bu Y, Gelman IH. SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition. Cancer Research. 66: 5599-607. PMID 16740695 DOI: 10.1158/0008-5472.CAN-05-4123  0.96
2006 Liu Y, Gao L, Gelman IH. SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis. Bmc Cancer. 6: 105. PMID 16638134 DOI: 10.1186/1471-2407-6-105  0.56
2006 Greenberg RS, Bernstein AM, Benezra M, Gelman IH, Taliana L, Masur SK. FAK-dependent regulation of myofibroblast differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1006-8. PMID 16585062 DOI: 10.1096/fj.05-4838fje  1
2006 Gelman IH, Gao L. SSeCKS/Gravin/AKAP12 metastasis suppressor inhibits podosome formation via RhoA- and Cdc42-dependent pathways. Molecular Cancer Research : McR. 4: 151-8. PMID 16547152 DOI: 10.1158/1541-7786.MCR-05-0252  0.56
2005 Moissoglu K, Sachdev S, Gelman IH. Enhanced v-Src-induced oncogenic transformation in the absence of focal adhesion kinase is mediated by phosphatidylinositol 3-kinase. Biochemical and Biophysical Research Communications. 330: 673-84. PMID 15809050 DOI: 10.1016/j.bbrc.2005.03.025  0.56
2003 Lee SW, Kim WJ, Choi YK, Song HS, Son MJ, Gelman IH, Kim YJ, Kim KW. SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nature Medicine. 9: 900-6. PMID 12808449 DOI: 10.1038/nm889  1
2003 Nelson PJ, D'Agati VD, Gries JM, Suarez JR, Gelman IH. Amelioration of nephropathy in mice expressing HIV-1 genes by the cyclin-dependent kinase inhibitor flavopiridol. The Journal of Antimicrobial Chemotherapy. 51: 921-9. PMID 12654740 DOI: 10.1093/jac/dkg175  1
2002 Husain M, Gusella GL, Klotman ME, Gelman IH, Ross MD, Schwartz EJ, Cara A, Klotman PE. HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. Journal of the American Society of Nephrology : Jasn. 13: 1806-15. PMID 12089376 DOI: 10.1097/01.ASN.0000019642.55998.69  1
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