Charles R. Holst, Ph.D. - Publications

2003 University of California, San Francisco, San Francisco, CA 
Cell Biology, Oncology, Genetics

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Koltun ES, Tsuhako AL, Brown DS, Aay N, Arcalas A, Chan V, Du H, Engst S, Ferguson K, Franzini M, Galan A, Holst CR, Huang P, Kane B, Kim MH, et al. Discovery of XL413, a potent and selective CDC7 inhibitor. Bioorganic & Medicinal Chemistry Letters. 22: 3727-31. PMID 22560567 DOI: 10.1016/j.bmcl.2012.04.024  0.56
2012 Leahy JW, Buhr CA, Johnson HW, Kim BG, Baik T, Cannoy J, Forsyth TP, Jeong JW, Lee MS, Ma S, Noson K, Wang L, Williams M, Nuss JM, Brooks E, ... ... Holst C, et al. Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors. Journal of Medicinal Chemistry. 55: 5467-82. PMID 22548342 DOI: 10.1021/jm300403a  0.56
2011 Lyman SK, Crawley SC, Gong R, Adamkewicz JI, McGrath G, Chew JY, Choi J, Holst CR, Goon LH, Detmer SA, Vaclavikova J, Gerritsen ME, Blake RA. High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888. Plos One. 6: e17692. PMID 21408192 DOI: 10.1371/journal.pone.0017692  0.56
2007 Garbe JC, Holst CR, Bassett E, Tlsty T, Stampfer MR. Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis. Cell Cycle (Georgetown, Tex.). 6: 1927-36. PMID 17671422 DOI: 10.4161/Cc.6.15.4519  0.56
2007 Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz GD, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A. Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. Plos One. 2: e575. PMID 17593974 DOI: 10.1371/Journal.Pone.0000575  0.56
2006 Zhang J, Pickering CR, Holst CR, Gauthier ML, Tlsty TD. p16INK4a modulates p53 in primary human mammary epithelial cells. Cancer Research. 66: 10325-31. PMID 17079452 DOI: 10.1158/0008-5472.Can-06-1594  0.56
2006 McDermott KM, Zhang J, Holst CR, Kozakiewicz BK, Singla V, Tlsty TD. p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells. Plos Biology. 4: e51. PMID 16464125 DOI: 10.1371/Journal.Pbio.0040051  0.56
2004 Tlsty TD, Crawford YG, Holst CR, Fordyce CA, Zhang J, McDermott K, Kozakiewicz K, Gauthier ML. Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis. Journal of Mammary Gland Biology and Neoplasia. 9: 263-74. PMID 15557799 DOI: 10.1023/B:Jomg.0000048773.95897.5F  0.56
2003 Holst CR, Nuovo GJ, Esteller M, Chew K, Baylin SB, Herman JG, Tlsty TD. Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Research. 63: 1596-601. PMID 12670910  0.56
2001 Tlsty TD, Romanov SR, Kozakiewicz BK, Holst CR, Haupt LM, Crawford YG. Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence. Journal of Mammary Gland Biology and Neoplasia. 6: 235-43. PMID 11501583 DOI: 10.1023/A:1011369026168  0.56
2001 Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature. 409: 633-7. PMID 11214324 DOI: 10.1038/35054579  0.56
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