Stephen Byers - Publications

Affiliations: 
Cell Biology Georgetown University, Washington, DC 
Area:
Cell Biology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wathieu H, Issa NT, Fernandez AI, Mohandoss M, Tiek DM, Franke JL, Byers SW, Riggins RB, Dakshanamurthy S. Differential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method. Oncotarget. 8: 92926-92942. PMID 29190967 DOI: 10.18632/oncotarget.21669  0.36
2017 Issa NT, Wathieu H, Ojo A, Byers SW, Dakshanamurthy S. Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools. Current Drug Metabolism. PMID 28302026 DOI: 10.2174/1389200218666170316093301  0.36
2017 Simbulan-Rosenthal CM, Dakshanamurthy S, Gaur A, Chen YS, Fang HB, Abdussamad M, Zhou H, Zapas J, Calvert V, Petricoin EF, Atkins MB, Byers SW, Rosenthal DS. The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma. Oncotarget. PMID 28157711 DOI: 10.18632/oncotarget.14990  0.36
2016 Wathieu H, Issa NT, Mohandoss M, Byers SW, Dakshanamurthy S. A Network-based Systems Biology Platform for Predicting Disease-Metabolite Links. Combinatorial Chemistry & High Throughput Screening. PMID 28024464  0.36
2016 Issa NT, Kruger J, Wathieu H, Raja R, Byers SW, Dakshanamurthy S. DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing. Bmc Bioinformatics. 17: 202. PMID 27151405 DOI: 10.1186/s12859-016-1065-y  0.36
2016 Wathieu H, Issa NT, Byers SW, Dakshanamurthy S. Harnessing Polypharmacology with Computer-Aided Drug Design and Systems Biology. Current Pharmaceutical Design. PMID 26907947  0.36
2015 Issa NT, Peters OJ, Byers SW, Dakshanamurthy S. RepurposeVS: A Drug Repurposing-Focused Computational Method for Accurate Drug-Target Signature Predictions. Combinatorial Chemistry & High Throughput Screening. 18: 784-94. PMID 26234515  0.36
2015 Zhi X, Lin L, Yang S, Bhuvaneshwar K, Wang H, Gusev Y, Lee MH, Kallakury B, Shivapurkar N, Cahn K, Tian X, Marshall JL, Byers SW, He AR. βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin. Hepatology (Baltimore, Md.). 61: 598-612. PMID 25307947 DOI: 10.1002/hep.27558  0.44
2014 Issa NT, Byers SW, Dakshanamurthy S. Big data: the next frontier for innovation in therapeutics and healthcare. Expert Review of Clinical Pharmacology. 7: 293-8. PMID 24702684 DOI: 10.1586/17512433.2014.905201  0.36
2014 Assefnia S, Dakshanamurthy S, Guidry Auvil JM, Hampel C, Anastasiadis PZ, Kallakury B, Uren A, Foley DW, Brown ML, Shapiro L, Brenner M, Haigh D, Byers SW. Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Oncotarget. 5: 1458-74. PMID 24681547  0.44
2014 Brouxhon SM, Kyrkanides S, Teng X, O'Banion MK, Clarke R, Byers S, Ma L. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Molecular Carcinogenesis. 53: 893-906. PMID 23776059 DOI: 10.1002/mc.22048  0.44
2013 Madhavan S, Gusev Y, Natarajan TG, Song L, Bhuvaneshwar K, Gauba R, Pandey A, Haddad BR, Goerlitz D, Cheema AK, Juhl H, Kallakury B, Marshall JL, Byers SW, Weiner LM. Genome-wide multi-omics profiling of colorectal cancer identifies immune determinants strongly associated with relapse. Frontiers in Genetics. 4: 236. PMID 24312117 DOI: 10.3389/fgene.2013.00236  0.44
2013 Issa NT, Byers SW, Dakshanamurthy S. Drug repurposing: translational pharmacology, chemistry, computers and the clinic. Current Topics in Medicinal Chemistry. 13: 2328-36. PMID 24059462  0.36
2013 Brouxhon SM, Kyrkanides S, Teng X, Raja V, O'Banion MK, Clarke R, Byers S, Silberfeld A, Tornos C, Ma L. Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3234-46. PMID 23620408 DOI: 10.1158/1078-0432.CCR-12-2747  0.44
2013 Issa NT, Kruger J, Byers SW, Dakshanamurthy S. Drug repurposing a reality: from computers to the clinic. Expert Review of Clinical Pharmacology. 6: 95-7. PMID 23473587 DOI: 10.1586/ecp.12.79  0.36
2012 Catalina-Rodriguez O, Kolukula VK, Tomita Y, Preet A, Palmieri F, Wellstein A, Byers S, Giaccia AJ, Glasgow E, Albanese C, Avantaggiati ML. The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis. Oncotarget. 3: 1220-35. PMID 23100451  0.44
2012 Dakshanamurthy S, Issa NT, Assefnia S, Seshasayee A, Peters OJ, Madhavan S, Uren A, Brown ML, Byers SW. Predicting new indications for approved drugs using a proteochemometric method. Journal of Medicinal Chemistry. 55: 6832-48. PMID 22780961 DOI: 10.1021/jm300576q  0.44
2012 Clark PM, Dawany N, Dampier W, Byers SW, Pestell RG, Tozeren A. Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases. Inflammatory Bowel Diseases. 18: 2315-33. PMID 22488912 DOI: 10.1002/ibd.22958  0.44
2012 Adhikari S, Karmahapatra SK, Karve TM, Bandyopadhyay S, Woodrick J, Manthena PV, Glasgow E, Byers S, Saha T, Uren A. Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction. Bmc Research Notes. 5: 134. PMID 22405347 DOI: 10.1186/1756-0500-5-134  0.44
2012 Sahab ZJ, Kirilyuk A, Zhang L, Khamis ZI, Pompach P, Sung Y, Byers SW. Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites. Journal of Proteome Research. 11: 1913-23. PMID 22296162 DOI: 10.1021/pr2011044  0.44
2012 Sang QX, Man YG, Sung YM, Khamis ZI, Zhang L, Lee MH, Byers SW, Sahab ZJ. Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis. Clinical & Experimental Metastasis. 29: 143-53. PMID 22116632 DOI: 10.1007/s10585-011-9437-1  0.44
2011 Khamis ZI, Sahab ZJ, Byers SW, Sang QX. Novel stromal biomarkers in human breast cancer tissues provide evidence for the more malignant phenotype of estrogen receptor-negative tumors. Journal of Biomedicine & Biotechnology. 2011: 723650. PMID 21976967 DOI: 10.1155/2011/723650  0.44
2011 Madhavan S, Gusev Y, Harris M, Tanenbaum DM, Gauba R, Bhuvaneshwar K, Shinohara A, Rosso K, Carabet LA, Song L, Riggins RB, Dakshanamurthy S, Wang Y, Byers SW, Clarke R, et al. G-DOC: a systems medicine platform for personalized oncology. Neoplasia (New York, N.Y.). 13: 771-83. PMID 21969811 DOI: 10.1593/neo.11806  0.44
2011 Sahab ZJ, Man YG, Byers SW, Sang QX. Putative biomarkers and targets of estrogen receptor negative human breast cancer. International Journal of Molecular Sciences. 12: 4504-21. PMID 21845093 DOI: 10.3390/ijms12074504  0.44
2011 Adhikari S, Karmahapatra SK, Elias H, Dhopeshwarkar P, Williams RS, Byers S, Uren A, Roy R. Development of a novel assay for human tyrosyl DNA phosphodiesterase 2. Analytical Biochemistry. 416: 112-6. PMID 21620793 DOI: 10.1016/j.ab.2011.05.008  0.44
2011 Sahab ZJ, Hall MD, Me Sung Y, Dakshanamurthy S, Ji Y, Kumar D, Byers SW. Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the α-tubulin tyrosination cycle. Cancer Research. 71: 1219-28. PMID 21303978 DOI: 10.1158/0008-5472.CAN-10-2294  0.44
2010 Sahab ZJ, Hall MD, Zhang L, Cheema AK, Byers SW. Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26. Journal of Cancer. 1: 14-22. PMID 20842219  0.44
2010 Sahab ZJ, Man YG, Semaan SM, Newcomer RG, Byers SW, Sang QX. Alteration in protein expression in estrogen receptor alpha-negative human breast cancer tissues indicates a malignant and metastatic phenotype. Clinical & Experimental Metastasis. 27: 493-503. PMID 20602252 DOI: 10.1007/s10585-010-9338-8  0.44
2010 Prahalad P, Dakshanamurthy S, Ressom H, Byers SW. Retinoic acid mediates regulation of network formation by COUP-TFII and VE-cadherin expression by TGFbeta receptor kinase in breast cancer cells. Plos One. 5: e10023. PMID 20386594 DOI: 10.1371/journal.pone.0010023  0.44
2010 Beildeck ME, Gelmann EP, Byers SW. Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway. Experimental Cell Research. 316: 1763-72. PMID 20138864 DOI: 10.1016/j.yexcr.2010.02.001  0.44
2010 Yasuhara R, Yuasa T, Williams JA, Byers SW, Shah S, Pacifici M, Iwamoto M, Enomoto-Iwamoto M. Wnt/beta-catenin and retinoic acid receptor signaling pathways interact to regulate chondrocyte function and matrix turnover. The Journal of Biological Chemistry. 285: 317-27. PMID 19858186 DOI: 10.1074/jbc.M109.053926  0.44
2009 Beildeck ME, Islam M, Shah S, Welsh J, Byers SW. Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines. Plos One. 4: e7872. PMID 19924301 DOI: 10.1371/journal.pone.0007872  0.44
2009 Alper O, Stetler-Stevenson WG, Harris LN, Leitner WW, Ozdemirli M, Hartmann D, Raffeld M, Abu-Asab M, Byers S, Zhuang Z, Oldfield EH, Tong Y, Bergmann-Leitner E, Criss WE, Nagasaki K, et al. Novel anti-filamin-A antibody detects a secreted variant of filamin-A in plasma from patients with breast carcinoma and high-grade astrocytoma. Cancer Science. 100: 1748-56. PMID 19594548 DOI: 10.1111/j.1349-7006.2009.01244.x  0.44
2008 Endo Y, Deonauth K, Prahalad P, Hoxter B, Zhu Y, Byers SW. Role of Sox-9, ER81 and VE-cadherin in retinoic acid-mediated trans-differentiation of breast cancer cells. Plos One. 3: e2714. PMID 18628953 DOI: 10.1371/journal.pone.0002714  0.44
2007 Byers S, Shah S. Vitamin D and the regulation of Wnt/beta-catenin signaling and innate immunity in colorectal cancer. Nutrition Reviews. 65: S118-20. PMID 17867386 DOI: 10.1111/j.1753-4887.2007.tb00337.x  0.44
2007 Avvisato CL, Yang X, Shah S, Hoxter B, Li W, Gaynor R, Pestell R, Tozeren A, Byers SW. Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. Journal of Cell Science. 120: 2672-82. PMID 17635998 DOI: 10.1242/jcs.03476  0.44
2007 Dakshanamurthy S, Kim M, Brown ML, Byers SW. In-silico fragment-based identification of novel angiogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 4551-6. PMID 17591441 DOI: 10.1016/j.bmcl.2007.05.104  0.44
2006 Sakamaki T, Casimiro MC, Ju X, Quong AA, Katiyar S, Liu M, Jiao X, Li A, Zhang X, Lu Y, Wang C, Byers S, Nicholson R, Link T, Shemluck M, et al. Cyclin D1 determines mitochondrial function in vivo. Molecular and Cellular Biology. 26: 5449-69. PMID 16809779 DOI: 10.1128/MCB.02074-05  0.44
2006 Shah S, Islam MN, Dakshanamurthy S, Rizvi I, Rao M, Herrell R, Zinser G, Valrance M, Aranda A, Moras D, Norman A, Welsh J, Byers SW. The molecular basis of vitamin D receptor and beta-catenin crossregulation. Molecular Cell. 21: 799-809. PMID 16543149 DOI: 10.1016/j.molcel.2006.01.037  0.44
2005 Allen J, Khwaja F, Byers S, Djakiew D. The p75NTR mediates a bifurcated signal transduction cascade through the NF kappa B and JNK pathways to inhibit cell survival. Experimental Cell Research. 304: 69-80. PMID 15707575 DOI: 10.1016/j.yexcr.2004.10.020  0.44
2003 Ray R, Cabal-Manzano R, Moser AR, Waldman T, Zipper LM, Aigner A, Byers SW, Riegel AT, Wellstein A. Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis. Cancer Research. 63: 8085-9. PMID 14678957  0.44
2003 Shah S, Hecht A, Pestell R, Byers SW. Trans-repression of beta-catenin activity by nuclear receptors. The Journal of Biological Chemistry. 278: 48137-45. PMID 12972427 DOI: 10.1074/jbc.M307154200  0.44
2003 Song LN, Herrell R, Byers S, Shah S, Wilson EM, Gelmann EP. Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription. Molecular and Cellular Biology. 23: 1674-87. PMID 12588987 DOI: 10.1128/MCB.23.5.1674-1687.2003  0.44
2000 Truica CI, Byers S, Gelmann EP. β-catenin affects androgen receptor transcriptional activity and ligand specificity Cancer Research. 60: 4709-4713. PMID 10987273  0.44
1995 Seslar S, Nakamura T, Byers S. Tumor-stroma interactions and stromal cell density regulate hepatocyte growth factor protein levels: A role for transforming growth factor-β activation Endocrinology. 136: 1945-1953. PMID 7720642  0.44
1992 Pelletier RM, Byers SW. The blood-testis barrier and Sertoli cell junctions: Structural considerations Microscopy Research and Technique. 20: 3-33. PMID 1611148  0.44
1990 Byers S, Graham R. Distribution of sodium-potassium ATPase in the rat testis and epididymis American Journal of Anatomy. 188: 31-43. PMID 1693257  0.44
1988 Byers S, Richardson L, Parker C. Isolation and characterization of epididymal epithelial cell plasma membranes Biology of Reproduction. 38: 201-209. PMID 3365469  0.44
1988 Byers S. Epithelial barriers in the testis and epididymis: Methodology immuno contraceptive and AIDS Advances in Contraceptive Delivery Systems. 4: 369-407.  0.44
1987 Parker CC, Byers SW. Transferrin-S-S-Ricin A conjugate inhibits protein synthesis in cultured rat Sertoli cells Annals of the New York Academy of Sciences. 513: 434-436.  0.44
1984 Byers SW. Effect of scrotal insulation on the ability of ram testes to produce testosterone in vitro Journal of Reproduction and Fertility. 71: 17-21. PMID 6726677  0.44
1984 Byers SW, Glover TD. Effect of scrotal insulation on the pituitary-testicular axis of the rat Journal of Reproduction and Fertility. 71: 23-31. PMID 6427455  0.44
1983 Qasba PK, Hewlett IK, Byers S. The presence of the milk protein, α-lactalbumin and its mRNA in the rat epididymis Biochemical and Biophysical Research Communications. 117: 306-312. PMID 6419737 DOI: 10.1016/0006-291X(83)91576-0  0.44
1983 Byers SW, Glover TD. Effect of scrotal insulation on seminal fructose, peripheral plasma prolactin, and circulating steroids in rams Animal Reproduction Science. 5: 295-301. DOI: 10.1016/0378-4320(83)90051-9  0.44
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