| Year |
Citation |
Score |
| 2023 |
Ranjan A, Thoenen EA, Kaida A, Wood S, Van Dyke T, Iwakuma T. Characterization of an Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model. Cancers. 15. PMID 37760565 DOI: 10.3390/cancers15184596 |
0.362 |
|
| 2022 |
Adhikari AS, Sullivan T, Bargaje R, Lu L, O'Sullivan TN, Song Y, Van Dyke T. Abrogation of Rb Tumor Suppression Initiates GBM in Differentiated Astrocytes by Driving a Progenitor Cell Program. Frontiers in Oncology. 12: 904479. PMID 35814428 DOI: 10.3389/fonc.2022.904479 |
0.331 |
|
| 2020 |
Shi M, Whorton AE, Sekulovski N, Paquet M, MacLean JA, Song Y, Van Dyke T, Hayashi K. Inactivation of TRP53, PTEN, RB1 and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis. Biology of Reproduction. PMID 31930396 DOI: 10.1093/biolre/ioaa008 |
0.372 |
|
| 2017 |
Song Y, Sullivan T, Klarmann K, Gilbert D, O'Sullivan TN, Lu L, Wang S, Haines DC, Van Dyke T, Keller JR. RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice. Plos One. 12: e0171510. PMID 28158249 DOI: 10.1371/journal.pone.0171510 |
0.328 |
|
| 2015 |
El Meskini R, Iacovelli AJ, Kulaga A, Gumprecht M, Martin PL, Baran M, Householder DB, Van Dyke T, Weaver Ohler Z. A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors. Disease Models & Mechanisms. 8: 45-56. PMID 25431423 DOI: 10.1242/dmm.018168 |
0.351 |
|
| 2014 |
Day CP, Carter J, Weaver Ohler Z, Bonomi C, El Meskini R, Martin P, Graff-Cherry C, Feigenbaum L, Tüting T, Van Dyke T, Hollingshead M, Merlino G. "Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts. Plos One. 9: e109956. PMID 25369133 DOI: 10.1371/journal.pone.0109956 |
0.336 |
|
| 2014 |
Szabova L, Bupp S, Kamal M, Householder DB, Hernandez L, Schlomer JJ, Baran ML, Yi M, Stephens RM, Annunziata CM, Martin PL, Van Dyke TA, Weaver Ohler Z, Difilippantonio S. Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer. Plos One. 9: e95649. PMID 24748377 DOI: 10.1371/Journal.Pone.0095649 |
0.316 |
|
| 2014 |
Pérez de Castro I, Aguirre-Portolés C, Fernández-Miranda G, Cañamero M, Cowley DO, Van Dyke T, Malumbres M. Requirements for Aurora-A in tissue regeneration and tumor development in adult mammals. Cancer Research. 73: 6804-15. PMID 24242071 DOI: 10.1158/0008-5472.CAN-13-0586 |
0.391 |
|
| 2013 |
Song Y, Gilbert D, O'Sullivan TN, Yang C, Pan W, Fathalizadeh A, Lu L, Haines DC, Martin PL, Van Dyke T. Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues. Plos One. 8: e80459. PMID 24312475 DOI: 10.1371/Journal.Pone.0080459 |
0.356 |
|
| 2012 |
Yoon Y, Cowley DO, Gallant J, Jones SN, Van Dyke T, Rivera-Pérez JA. Conditional Aurora A deficiency differentially affects early mouse embryo patterning Developmental Biology. 371: 77-85. PMID 22939930 DOI: 10.1016/j.ydbio.2012.08.010 |
0.337 |
|
| 2012 |
Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, Householder DB, Baran ML, Yi M, Song Y, Sun W, McDunn JE, Martin PL, Van Dyke T, Difilippantonio S. Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer. Cancer Research. 72: 4141-53. PMID 22617326 DOI: 10.1158/0008-5472.Can-11-3834 |
0.382 |
|
| 2012 |
Serber DW, Rogala A, Makarem M, Rosson GB, Simin K, Godfrey V, Van Dyke T, Eaves CJ, Bultman SJ. The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner. Plos One. 7: e31346. PMID 22363625 DOI: 10.1371/Journal.Pone.0031346 |
0.437 |
|
| 2011 |
Cook DR, Solski PA, Bultman SJ, Kauselmann G, Schoor M, Kuehn R, Friedman LS, Cowley DO, Van Dyke T, Yeh JJ, Johnson L, Der CJ. The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration. Genes & Cancer. 2: 932-42. PMID 22701760 DOI: 10.1177/1947601912437035 |
0.402 |
|
| 2011 |
Lu X, Yang C, Yin C, Van Dyke T, Simin K. Apoptosis is the essential target of selective pressure against p53, whereas loss of additional p53 functions facilitates carcinoma progression. Molecular Cancer Research : McR. 9: 430-9. PMID 21385880 DOI: 10.1158/1541-7786.Mcr-10-0277 |
0.6 |
|
| 2010 |
Walrath JC, Hawes JJ, Van Dyke T, Reilly KM. Genetically engineered mouse models in cancer research. Advances in Cancer Research. 106: 113-64. PMID 20399958 DOI: 10.1016/S0065-230X(10)06004-5 |
0.316 |
|
| 2010 |
Chen S, Sanford CA, Sun J, Choi V, Van Dyke T, Samulski RJ, Rathmell WK. VHL and PTEN loss coordinate to promote mouse liver vascular lesions. Angiogenesis. 13: 59-69. PMID 20221685 DOI: 10.1007/S10456-010-9164-2 |
0.3 |
|
| 2009 |
DelBove J, Kuwahara Y, Mora-Blanco EL, Godfrey V, Funkhouser WK, Fletcher CD, Van Dyke T, Roberts CW, Weissman BE. Inactivation of SNF5 cooperates with p53 loss to accelerate tumor formation in Snf5(+/-);p53(+/-) mice. Molecular Carcinogenesis. 48: 1139-48. PMID 19676100 DOI: 10.1002/Mc.20568 |
0.454 |
|
| 2009 |
Schliekelman M, Cowley DO, O'Quinn R, Oliver TG, Lu C, Salmon ED, Van Dyke T. Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis Cancer Research. 69: 45-54. PMID 19117986 DOI: 10.1158/0008-5472.Can-07-6330 |
0.666 |
|
| 2009 |
Cowley DO, Rivera-Pérez JA, Schliekelman M, He YJ, Oliver TG, Lu C, O'Quinn R, Salmon ED, Magnuson T, Van Dyke T. Aurora-a kinase is essential for bipolar spindle formation and early development Molecular and Cellular Biology. 29: 1059-1071. PMID 19075002 DOI: 10.1128/Mcb.01062-08 |
0.683 |
|
| 2008 |
Lu X, Yang C, Hill R, Yin C, Hollander MC, Fornace AJ, Van Dyke T. Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival Cancer Research. 68: 3579-3583. PMID 18483238 DOI: 10.1158/0008-5472.Can-07-5533 |
0.663 |
|
| 2007 |
Chai J, Lu X, Godfrey V, Fletcher C, Roberts CW, Van Dyke T, Weissman BE. Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation. Cancer Research. 67: 3002-9. PMID 17409406 DOI: 10.1158/0008-5472.Can-06-4207 |
0.605 |
|
| 2006 |
McLear JA, Garcia-Fresco G, Bhat MA, Van Dyke TA. In vivo inactivation of pRb, p107 and p130 in murine neuroprogenitor cells leads to major CNS developmental defects and high seizure rates. Molecular and Cellular Neurosciences. 33: 260-73. PMID 16979903 DOI: 10.1016/J.Mcn.2006.07.012 |
0.63 |
|
| 2005 |
Hill R, Song Y, Cardiff RD, Van Dyke T. Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell. 123: 1001-11. PMID 16360031 DOI: 10.1016/J.Cell.2005.09.030 |
0.638 |
|
| 2005 |
Hill R, Song Y, Cardiff RD, Van Dyke T. Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model. Cancer Research. 65: 10243-54. PMID 16288012 DOI: 10.1158/0008-5472.Can-05-1579 |
0.59 |
|
| 2005 |
Cowley DO, Muse GW, Van Dyke T. A dominant interfering Bub1 mutant is insufficient to induce or alter thymic tumorigenesis in vivo, even in a sensitized genetic background. Molecular and Cellular Biology. 25: 7796-802. PMID 16107724 DOI: 10.1128/MCB.25.17.7796-7802.2005 |
0.484 |
|
| 2005 |
Xiao A, Yin C, Yang C, Di Cristofano A, Pandolfi PP, Van Dyke T. Somatic induction of Pten loss in a preclinical astrocytoma model reveals major roles in disease progression and avenues for target discovery and validation. Cancer Research. 65: 5172-80. PMID 15958561 DOI: 10.1158/0008-5472.Can-04-3902 |
0.458 |
|
| 2005 |
Nistér M, Tang M, Zhang XQ, Yin C, Beeche M, Hu X, Enblad G, van Dyke T, Wahl GM. p53 must be competent for transcriptional regulation to suppress tumor formation. Oncogene. 24: 3563-73. PMID 15750633 DOI: 10.1038/Sj.Onc.1208354 |
0.393 |
|
| 2004 |
Albright CD, Salganik RI, Van Dyke T. Dietary depletion of vitamin E and vitamin A inhibits mammary tumor growth and metastasis in transgenic mice. The Journal of Nutrition. 134: 1139-44. PMID 15113960 DOI: 10.1093/jn/134.5.1139 |
0.321 |
|
| 2004 |
Simin K, Wu H, Lu L, Pinkel D, Albertson D, Cardiff RD, Van Dyke T. pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia. Plos Biology. 2: E22. PMID 14966529 DOI: 10.1371/journal.pbio.0020022 |
0.485 |
|
| 2003 |
Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP. Pten dose dictates cancer progression in the prostate. Plos Biology. 1: E59. PMID 14691534 DOI: 10.1371/Journal.Pbio.0000059 |
0.301 |
|
| 2002 |
Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/Sj.Onc.1205936 |
0.302 |
|
| 2002 |
Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 1: 157-68. PMID 12086874 DOI: 10.1016/S1535-6108(02)00029-6 |
0.389 |
|
| 2002 |
Tolbert D, Lu X, Yin C, Tantama M, Van Dyke T. p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo. Molecular and Cellular Biology. 22: 370-7. PMID 11739748 DOI: 10.1128/Mcb.22.1.370-377.2002 |
0.607 |
|
| 2000 |
Salganik RI, Albright CD, Rodgers J, Kim J, Zeisel SH, Sivashinskiy MS, Van Dyke TA. Dietary antioxidant depletion: enhancement of tumor apoptosis and inhibition of brain tumor growth in transgenic mice. Carcinogenesis. 21: 909-14. PMID 10783311 |
0.309 |
|
| 1994 |
Van Dyke TA. Analysis of viral-host protein interactions and tumorigenesis in transgenic mice Seminars in Cancer Biology. 5: 47-60. PMID 8186388 |
0.391 |
|
| 1987 |
van Dyke TA, Finlay C, Miller D, Marks J, Lozano G, Levine AJ. Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice Journal of Virology. 61: 2029-2032. PMID 3033329 DOI: 10.1128/Jvi.61.6.2029-2032.1987 |
0.338 |
|
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