Sissy M. Jhiang - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Biochemistry

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Year Citation  Score
2023 Read ML, Brookes K, Zha L, Manivannan S, Kim J, Kocbiyik M, Fletcher A, Gorvin CM, Firth G, Fruhwirth GO, Nicola JP, Jhiang S, Ringel MD, Campbell MJ, Sunassee K, et al. Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37921808 DOI: 10.1158/1078-0432.CCR-23-2043  0.368
2021 Jhiang SM, Sipos JA. NIS in non-thyroidal tissues and impact on thyroid cancer therapy. Endocrine-Related Cancer. PMID 33974556 DOI: 10.1530/ERC-21-0035  0.403
2020 Jhiang SM, Konda B, Sipos JA, Nabhan F. Prospects for Re-differentiating Agents in the Use of Radioactive Iodine Therapy for Thyroid Cancer. Thyroid : Official Journal of the American Thyroid Association. PMID 32106791 DOI: 10.1089/Thy.2020.0143  0.397
2019 Liu J, Dong S, Wang H, Li L, Ye Q, Li Y, Miao J, Jhiang S, Zhao J, Zhao Y. Two distinct E3 ligases, SCF and HECW1, degrade thyroid transcription factor 1 in normal thyroid epithelial and follicular thyroid carcinoma cells, respectively. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900415R. PMID 31238008 DOI: 10.1096/Fj.201900415R  0.471
2019 Robb R, Yang L, Shen C, Wolfe A, Webb A, Zhang X, Vedaie M, Saji M, Jhiang SM, Ringel MD, Williams TM. Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAF Mutant Thyroid Cancer Cells by Constraining DNA Double-strand Break Repair. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31097454 DOI: 10.1158/1078-0432.Ccr-18-3625  0.402
2019 Hurst Z, Liyanarachchi S, He H, Brock P, Sipos JA, Nabhan F, Kebebew E, Green P, Cote GJ, Sherman SI, Walker CJ, Chang YS, Xue S, Hollingsworth B, Li W, ... ... Jhiang SM, et al. Risk Haplotypes Uniquely Associated with Radioiodine Refractory Thyroid Cancer Patients of High African Ancestry. Thyroid : Official Journal of the American Thyroid Association. PMID 30654714 DOI: 10.1089/Thy.2018.0687  0.336
2018 Feng F, Yehia L, Ni Y, Chang YS, Jhiang SM, Eng C. A non-pump function of sodium iodide symporter in thyroid cancer via crosstalk with PTEN signaling. Cancer Research. PMID 30217930 DOI: 10.1158/0008-5472.Can-18-1954  0.513
2018 Kotlarek M, Kubiak A, Czetwertyńska M, Świerniak M, Gierlikowski W, Kolanowska M, Bakuła-Zalewska E, Jhiang SM, Jażdżewski K, Wójcicka A. The rs2910164 Genetic Variant of miR-146a-3p Is Associated with Increased Overall Mortality in Patients with Follicular Variant Papillary Thyroid Carcinoma. International Journal of Molecular Sciences. 19. PMID 29495389 DOI: 10.3390/Ijms19030655  0.319
2017 Ashtekar A, Huk D, Magner A, La Perle K, Zhang X, Piruat J, Lopez-Barneo J, Jhiang S, Kirschner L. Sdhd ablation promotes thyroid tumorigenesis by inducing a stem-like phenotype. Endocrine-Related Cancer. PMID 28928232 DOI: 10.1530/Erc-17-0229  0.726
2017 Cheng P, Hollingsworth B, Scarberry D, Shen DH, Powell K, Smart SC, Beech J, Sheng X, Kirschner LS, Menq CH, Jhiang SM. Automated microSPECT/microCT image analysis of the mouse thyroid gland. Thyroid : Official Journal of the American Thyroid Association. PMID 28920557 DOI: 10.1089/Thy.2017.0264  0.638
2016 Hollingsworth B, Senter L, Zhang X, Brock GN, Jarjour W, Nagy R, Brock P, Coombes KR, Kloos R, Ringel MD, Sipos J, Lattimer I, Carrau R, Jhiang SM. Risk Factors of (131)I-Induced Salivary Gland Damage in Thyroid Cancer Patients. The Journal of Clinical Endocrinology and Metabolism. jc20161605. PMID 27533304 DOI: 10.1210/Jc.2016-1605  0.371
2015 Bible KC, Cote GJ, Demeure MJ, Elisei R, Jhiang S, Ringel MD. Correlative Studies in Clinical Trials: A Position Statement From the International Thyroid Oncology Group. The Journal of Clinical Endocrinology and Metabolism. 100: 4387-95. PMID 26418285 DOI: 10.1210/Jc.2015-2818  0.364
2015 Lakshmanan A, Scarberry D, Green JA, Zhang X, Selmi-Ruby S, Jhiang SM. Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin. Oncotarget. PMID 26397139 DOI: 10.18632/Oncotarget.5172  0.502
2015 Lakshmanan A, Wojcicka A, Kotlarek M, Zhang X, Jazdzewski K, Jhiang SM. microRNA-339-5p modulates Na+/I- symporter-mediated radioiodide uptake. Endocrine-Related Cancer. 22: 11-21. PMID 25404690 DOI: 10.1530/Erc-14-0439  0.317
2015 Lakshmanan A, Scarberry D, Green JA, Zhang X, Selmi-Ruby S, Jhiang SM. Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin Oncotarget. 6: 31792-31804. DOI: 10.18632/oncotarget.5172  0.405
2014 Lakshmanan A, Scarberry D, Shen DH, Jhiang SM. Modulation of sodium iodide symporter in thyroid cancer. Hormones & Cancer. 5: 363-73. PMID 25234361 DOI: 10.1007/S12672-014-0203-0  0.684
2014 Lakshmanan A, Doseff AI, Ringel MD, Saji M, Rousset B, Zhang X, Jhiang SM. Apigenin in combination with Akt inhibition significantly enhances thyrotropin-stimulated radioiodide accumulation in thyroid cells. Thyroid : Official Journal of the American Thyroid Association. 24: 878-87. PMID 24400871 DOI: 10.1089/Thy.2013.0614  0.491
2013 La Perle KM, Kim DC, Hall NC, Bobbey A, Shen DH, Nagy RS, Wakely PE, Lehman A, Jarjoura D, Jhiang SM. Modulation of sodium/iodide symporter expression in the salivary gland. Thyroid : Official Journal of the American Thyroid Association. 23: 1029-36. PMID 23441638 DOI: 10.1089/Thy.2012.0571  0.819
2013 Zhang Z, Beyer S, Jhiang SM. MEK inhibition leads to lysosome-mediated Na+/I- symporter protein degradation in human breast cancer cells. Endocrine-Related Cancer. 20: 241-50. PMID 23404856 DOI: 10.1530/Erc-12-0342  0.64
2013 Lakshmanan A, Jhiang SM. Abstract 87: Apigenin further enhances Akti1/2-induced radioactive iodine uptake (RAIU) and rescues TGF-β1-reduced RAIU in PCCl3 rat thyroid cells. Cancer Research. 73: 87-87. DOI: 10.1158/1538-7445.Am2013-87  0.533
2012 Brandt MP, Kloos RT, Shen DH, Zhang X, Liu YY, Jhiang SM. Micro-single-photon emission computed tomography image acquisition and quantification of sodium-iodide symporter-mediated radionuclide accumulation in mouse thyroid and salivary glands. Thyroid : Official Journal of the American Thyroid Association. 22: 617-24. PMID 22540327 DOI: 10.1089/Thy.2011.0348  0.625
2012 Liu YY, Zhang X, Ringel MD, Jhiang SM. Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells. Endocrine-Related Cancer. 19: 291-304. PMID 22355179 DOI: 10.1530/Erc-11-0288  0.563
2011 Beyer SJ, Zhang X, Jimenez RE, Lee ML, Richardson AL, Huang K, Jhiang SM. Microarray analysis of genes associated with cell surface NIS protein levels in breast cancer. Bmc Research Notes. 4: 397. PMID 21989294 DOI: 10.1186/1756-0500-4-397  0.438
2011 Beyer S, Lakshmanan A, Liu YY, Zhang X, Wapnir I, Smolenski A, Jhiang S. KT5823 differentially modulates sodium iodide symporter expression, activity, and glycosylation between thyroid and breast cancer cells. Endocrinology. 152: 782-92. PMID 21209020 DOI: 10.1210/En.2010-0782  0.511
2011 Liu YY, Brandt MP, Shen DH, Kloos RT, Zhang X, Jhiang SM. Single photon emission computed tomography imaging for temporal dynamics of thyroidal and salivary radionuclide accumulation in 17-allyamino-17-demothoxygeldanamycin-treated thyroid cancer mouse model. Endocrine-Related Cancer. 18: 27-37. PMID 20943721 DOI: 10.1677/Erc-10-0185  0.667
2010 Jhiang SM, Shah MH. Prospects for small interfering RNA therapeutics in thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 20: 1049-50. PMID 20883169 DOI: 10.1089/Thy.2010.1660  0.334
2009 Huang Y, Wan J, Cheng MC, Zhang Z, Jhiang SM, Menq CH. Three-axis rapid steering of optically propelled micro/nanoparticles. The Review of Scientific Instruments. 80: 063107. PMID 19566196 DOI: 10.1063/1.3156838  0.429
2009 Beyer SJ, Jimenez RE, Shapiro CL, Cho JY, Jhiang SM. Do cell surface trafficking impairments account for variable cell surface sodium iodide symporter levels in breast cancer? Breast Cancer Research and Treatment. 115: 205-212. PMID 18500672 DOI: 10.1007/S10549-008-0059-5  0.47
2007 Knostman KA, Venkateswaran A, Zimmerman B, Capen CC, Jhiang SM. Creation and characterization of a doxycycline-inducible mouse model of thyroid-targeted RET/PTC1 oncogene and luciferase reporter gene coexpression. Thyroid : Official Journal of the American Thyroid Association. 17: 1181-8. PMID 18004977 DOI: 10.1089/Thy.2007.0224  0.743
2007 Vadysirisack DD, Chen ES, Zhang Z, Tsai MD, Chang GD, Jhiang SM. Identification of in vivo phosphorylation sites and their functional significance in the sodium iodide symporter. The Journal of Biological Chemistry. 282: 36820-8. PMID 17913707 DOI: 10.1074/Jbc.M706817200  0.788
2007 Knostman KA, McCubrey JA, Morrison CD, Zhang Z, Capen CC, Jhiang SM. PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer. Bmc Cancer. 7: 137. PMID 17651485 DOI: 10.1186/1471-2407-7-137  0.615
2007 Vadysirisack DD, Venkateswaran A, Zhang Z, Jhiang SM. MEK signaling modulates sodium iodide symporter at multiple levels and in a paradoxical manner. Endocrine-Related Cancer. 14: 421-32. PMID 17639055 DOI: 10.1677/Erc.1.01263  0.801
2007 Knostman KAB, Jhiang SM, Capen CC. Genetic alterations in thyroid cancer: The role of mouse models Veterinary Pathology. 44: 1-14. PMID 17197619 DOI: 10.1354/Vp.44-1-1  0.312
2006 Vadysirisack DD, Shen DH, Jhiang SM. Correlation of Na+/I- symporter expression and activity: implications of Na+/I- symporter as an imaging reporter gene. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 182-90. PMID 16391203  0.815
2006 Sarquis MS, Weber F, Shen L, Broelsch CE, Jhiang SM, Zedenius J, Frilling A, Eng C. High frequency of loss of heterozygosity in imprinted, compared with nonimprinted, genomic regions in follicular thyroid carcinomas and atypical adenomas. The Journal of Clinical Endocrinology and Metabolism. 91: 262-9. PMID 16249278 DOI: 10.1210/Jc.2005-1880  0.444
2005 Morgenstern KE, Vadysirisack DD, Zhang Z, Cahill KV, Foster JA, Burns JA, Kloos RT, Jhiang SM. Expression of sodium iodide symporter in the lacrimal drainage system: implication for the mechanism underlying nasolacrimal duct obstruction in I(131)-treated patients. Ophthalmic Plastic and Reconstructive Surgery. 21: 337-44. PMID 16234694 DOI: 10.1097/01.Iop.0000179369.75569.A8  0.813
2005 Marsee DK, Vadysirisack DD, Morrison CD, Prasad ML, Eng C, Duh QY, Rauen KA, Kloos RT, Jhiang SM. Variable expression of coxsackie-adenovirus receptor in thyroid tumors: implications for adenoviral gene therapy. Thyroid : Official Journal of the American Thyroid Association. 15: 977-87. PMID 16187905 DOI: 10.1089/Thy.2005.15.977  0.809
2005 Zhang Z, Liu YY, Jhiang SM. Cell surface targeting accounts for the difference in iodide uptake activity between human Na+/I- symporter and rat Na+/I- symporter. The Journal of Clinical Endocrinology and Metabolism. 90: 6131-40. PMID 16105966 DOI: 10.1210/Jc.2005-0895  0.622
2004 Venkateswaran A, Marsee DK, Green SH, Jhiang SM. Forskolin, 8-Br-3',5'-cyclic adenosine 5'-monophosphate, and catalytic protein kinase A expression in the nucleus increase radioiodide uptake and sodium/iodide symporter protein levels in RET/PTC1-expressing cells. The Journal of Clinical Endocrinology and Metabolism. 89: 6168-72. PMID 15579773 DOI: 10.1210/Jc.2004-1414  0.824
2004 Knostman KA, Cho JY, Ryu KY, Lin X, McCubrey JA, Hla T, Liu CH, Di Carlo E, Keri R, Zhang M, Hwang DY, Kisseberth WC, Capen CC, Jhiang SM. Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer. The Journal of Clinical Endocrinology and Metabolism. 89: 5196-203. PMID 15472226 DOI: 10.1210/Jc.2004-0907  0.804
2004 Miyagi E, Braga-Basaria M, Hardy E, Vasko V, Burman KD, Jhiang S, Saji M, Ringel MD. Chronic expression of RET/PTC 3 enhances basal and insulin-stimulated PI3 kinase/AKT signaling and increases IRS-2 expression in FRTL-5 thyroid cells Molecular Carcinogenesis. 41: 98-107. PMID 15378648 DOI: 10.1002/Mc.20042  0.407
2004 Aldred MA, Huang Y, Liyanarachchi S, Pellegata NS, Gimm O, Jhiang S, Davuluri RV, de la Chapelle A, Eng C. Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3531-9. PMID 15337802 DOI: 10.1200/Jco.2004.08.127  0.461
2004 Marsee DK, Venkateswaran A, Tao H, Vadysirisack D, Zhang Z, Vandre DD, Jhiang SM. Inhibition of heat shock protein 90, a novel RET/PTC1-associated protein, increases radioiodide accumulation in thyroid cells. The Journal of Biological Chemistry. 279: 43990-7. PMID 15302866 DOI: 10.1074/Jbc.M407503200  0.801
2004 Lin X, Fischer AH, Ryu KY, Cho JY, Sferra TJ, Kloos RT, Mazzaferri EL, Jhiang SM. Application of the Cre/loxP system to enhance thyroid-targeted expression of sodium/iodide symporter. The Journal of Clinical Endocrinology and Metabolism. 89: 2344-50. PMID 15126562 DOI: 10.1210/Jc.2003-031963  0.817
2004 Burns JA, Morgenstern KE, Cahill KV, Foster JA, Jhiang SM, Kloos RT. Nasolacrimal obstruction secondary to I(131) therapy. Ophthalmic Plastic and Reconstructive Surgery. 20: 126-9. PMID 15083081 DOI: 10.1097/01.Iop.0000117340.41849.81  0.354
2004 Lin X, Ryu KY, Jhiang SM. Cloning of the 5'-flanking region of mouse sodium/iodide symporter and identification of a thyroid-specific and TSH-responsive enhancer. Thyroid : Official Journal of the American Thyroid Association. 14: 19-27. PMID 15009910 DOI: 10.1089/105072504322783803  0.726
2004 Marsee DK, Shen DH, MacDonald LR, Vadysirisack DD, Lin X, Hinkle G, Kloos RT, Jhiang SM. Imaging of metastatic pulmonary tumors following NIS gene transfer using single photon emission computed tomography. Cancer Gene Therapy. 11: 121-7. PMID 14730332 DOI: 10.1038/Sj.Cgt.7700661  0.782
2004 Shen DH, Marsee DK, Schaap J, Yang W, Cho JY, Hinkle G, Nagaraja HN, Kloos RT, Barth RF, Jhiang SM. Effects of dose, intervention time, and radionuclide on sodium iodide symporter (NIS)-targeted radionuclide therapy. Gene Therapy. 11: 161-9. PMID 14712300 DOI: 10.1038/Sj.Gt.3302147  0.796
2003 Barton KN, Tyson D, Stricker H, Lew YS, Heisey G, Koul S, de la Zerda A, Yin FF, Yan H, Nagaraja TN, Randall KA, Jin GK, Fenstermacher JD, Jhiang S, Ho Kim J, et al. GENIS: gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 508-18. PMID 12946325 DOI: 10.1016/S1525-0016(03)00153-9  0.354
2003 Fischer AH, Taysavang P, Jhiang SM. Nuclear envelope irregularity is induced by RET/PTC during interphase. The American Journal of Pathology. 163: 1091-100. PMID 12937150 DOI: 10.1016/S0002-9440(10)63468-2  0.404
2003 Aldred MA, Ginn-Pease ME, Morrison CD, Popkie AP, Gimm O, Hoang-Vu C, Krause U, Dralle H, Jhiang SM, Plass C, Eng C. Caveolin-1 and caveolin-2,together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis. Cancer Research. 63: 2864-71. PMID 12782592  0.424
2003 Aldred MA, Morrison C, Gimm O, Hoang-Vu C, Krause U, Dralle H, Jhiang S, Eng C. Peroxisome proliferator-activated receptor gamma is frequently downregulated in a diversity of sporadic nonmedullary thyroid carcinomas. Oncogene. 22: 3412-6. PMID 12776192 DOI: 10.1038/Sj.Onc.1206400  0.508
2003 La Perle KM, Blomme EA, Capen CC, Jhiang SM. Effect of exogenous human sodium iodide symporter expression on growth of MATLyLu cells. Thyroid : Official Journal of the American Thyroid Association. 13: 133-40. PMID 12699587 DOI: 10.1089/105072503321319431  0.749
2002 Kloos RT, Duvuuri V, Jhiang SM, Cahill KV, Foster JA, Burns JA. Nasolacrimal drainage system obstruction from radioactive iodine therapy for thyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. 87: 5817-20. PMID 12466391 DOI: 10.1210/Jc.2002-020210  0.311
2002 Buckwalter TL, Venkateswaran A, Lavender M, La Perle KM, Cho JY, Robinson ML, Jhiang SM. The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation. Oncogene. 21: 8166-72. PMID 12444552 DOI: 10.1038/Sj.Onc.1205938  0.771
2002 Patel A, Jhiang S, Dogra S, Terrell R, Powers PA, Fenton C, Dinauer CA, Tuttle RM, Francis GL. Differentiated thyroid carcinoma that express sodium-iodide symporter have a lower risk of recurrence for children and adolescents. Pediatric Research. 52: 737-44. PMID 12409522 DOI: 10.1203/00006450-200211000-00021  0.482
2002 Cho JY, Shen DH, Yang W, Williams B, Buckwalter TL, La Perle KM, Hinkle G, Pozderac R, Kloos R, Nagaraja HN, Barth RF, Jhiang SM. In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas. Gene Therapy. 9: 1139-45. PMID 12170377 DOI: 10.1038/Sj.Gt.3301787  0.809
2002 La Perle KM, Shen D, Buckwalter TL, Williams B, Haynam A, Hinkle G, Pozderac R, Capen CC, Jhiang SM. In vivo expression and function of the sodium iodide symporter following gene transfer in the MATLyLu rat model of metastatic prostate cancer. The Prostate. 50: 170-8. PMID 11813209 DOI: 10.1002/Pros.10046  0.789
2001 Shen DHY, Kloos RT, Mazzaferri EL, Jhiang SM. Sodium iodide symporter in health and disease Thyroid. 11: 415-425. PMID 11396700 DOI: 10.1089/105072501300176372  0.543
2000 Jhiang SM. The RET proto-oncogene in human cancers Oncogene. 19: 5590-5597. PMID 11114739 DOI: 10.1038/Sj.Onc.1203857  0.419
2000 Rillema JA, Yu TX, Jhiang SM. Effect of prolactin on sodium iodide symporter expression in mouse mammary gland explants American Journal of Physiology - Endocrinology and Metabolism. 279. PMID 11001757 DOI: 10.1152/Ajpendo.2000.279.4.E769  0.377
2000 Cho JY, Léveillé R, Kao R, Rousset B, Parlow AF, Burak WE, Mazzaferri EL, Jhiang SM. Hormonal regulation of radioiodide uptake activity and Na+/I- symporter expression in mammary glands Journal of Clinical Endocrinology and Metabolism. 85: 2936-2943. PMID 10946907 DOI: 10.1210/Jcem.85.8.6727  0.691
2000 La Perle KM, Jhiang SM, Capen CC. Loss of p53 promotes anaplasia and local invasion in ret/PTC1-induced thyroid carcinomas. The American Journal of Pathology. 157: 671-7. PMID 10934169 DOI: 10.1016/S0002-9440(10)64577-4  0.705
2000 Cho JY, Xing S, Liu X, Buckwalter TL, Hwa L, Sferra TJ, Chiu IM, Jhiang SM. Expression and activity of human Na+/I- symporter in human glioma cells by adenovirus-mediated gene delivery. Gene Therapy. 7: 740-9. PMID 10822300 DOI: 10.1038/Sj.Gt.3301170  0.801
1999 Castro MR, Bergert ER, Beito TG, Roche PC, Ziesmer SC, Jhiang SM, Goellner JR, Morris JC. Monoclonal antibodies against the human sodium iodide symporter: Utility for immunocytochemistry of thyroid cancer Journal of Endocrinology. 163: 495-504. PMID 10588823 DOI: 10.1677/Joe.0.1630495  0.323
1999 Cho JY, Sagartz JE, Capen CC, Mazzaferri EL, Jhiang SM. Early cellular abnormalities induced by RET/PTC1 oncogene in thyroid-targeted transgenic mice Oncogene. 18: 3659-3665. PMID 10380889 DOI: 10.1038/Sj.Onc.1202709  0.704
1999 Ryu KY, Senokozlieff ME, Smanik PA, Wong MG, Siperstein AE, Duh QY, Clark OH, Mazzaferri EL, Jhiang SM. Development of reverse transcription-competitive polymerase chain reaction method to quantitate the expression levels of human sodium iodide symporter. Thyroid : Official Journal of the American Thyroid Association. 9: 405-9. PMID 10319949 DOI: 10.1089/Thy.1999.9.405  0.669
1998 Jhiang SM, Cho JY, Furminger TL, Sagartz JE, Tong Q, Capen CC, Mazzaferri EL. Thyroid carcinomas in RET/PTC transgenic mice Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 154: 265-270. PMID 10027006 DOI: 10.1007/978-3-642-46870-4_17  0.518
1998 Kosugi S, Sato Y, Matsuda A, Ohyama Y, Fujieda K, Inomata H, Kameya T, Isozaki O, Jhiang SM. High prevalence of T354P sodium/iodide symporter gene mutation in Japanese patients with iodide transport defect who have heterogeneous clinical pictures Journal of Clinical Endocrinology and Metabolism. 83: 4123-4129. PMID 9814502 DOI: 10.1210/Jcem.83.11.5229  0.376
1998 Jhiang SM, Cho JY, Ryu KY, DeYoung BR, Smanik PA, McGaughy VR, Fischer AH, Mazzaferri EL. An immunohistochemical study of Na+/I- symporter in human thyroid tissues and salivary gland tissues. Endocrinology. 139: 4416-9. PMID 9751526 DOI: 10.1210/Endo.139.10.6329  0.737
1998 Kosugi S, Inoue S, Matsuda A, Jhiang SM. Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients Journal of Clinical Endocrinology and Metabolism. 83: 3373-3376. PMID 9745458 DOI: 10.1210/Jcem.83.9.5243  0.357
1998 Ryu KY, Tong Q, Jhiang SM. Promoter characterization of the human Na+/I- symporter. The Journal of Clinical Endocrinology and Metabolism. 83: 3247-51. PMID 9745437 DOI: 10.1210/Jcem.83.9.5118  0.636
1998 Pohlenz J, Rosenthal IM, Weiss RE, Jhiang SM, Burant C, Refetoff S. Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site. The Journal of Clinical Investigation. 101: 1028-35. PMID 9486973 DOI: 10.1172/Jci1504  0.389
1998 Xing S, Furminger TL, Tong Q, Jhiang SM. Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells Journal of Biological Chemistry. 273: 4909-4914. PMID 9478934 DOI: 10.1074/Jbc.273.9.4909  0.398
1997 Tong Q, Ryu KY, Jhiang SM. Promoter characterization of the rat Na+/I- symporter gene. Biochemical and Biophysical Research Communications. 239: 34-41. PMID 9345265 DOI: 10.1006/Bbrc.1997.7432  0.649
1997 Smanik PA, Ryu KY, Theil KS, Mazzaferri EL, Jhiang SM. Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter. Endocrinology. 138: 3555-8. PMID 9231811 DOI: 10.1210/Endo.138.8.5262  0.659
1997 Sagartz JE, Jhiang SM, Tong Q, Capen CC. Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene Laboratory Investigation. 76: 307-318. PMID 9121114  0.385
1997 Tong Q, Xing S, Jhiang SM. Leucine zipper-mediated dimerization is essential for the PTC1 oncogenic activity Journal of Biological Chemistry. 272: 9043-9047. PMID 9083029 DOI: 10.1074/Jbc.272.14.9043  0.382
1996 Jossart GH, O'Brien B, Cheng JF, Tong Q, Jhiang SM, Duh Q, Clark OH, Weier HUG. A novel multicolor hybridization scheme applied to localization of a transcribed sequence (D10S170/H4) and deletion mapping in the thyroid cancer cell line TPC-1 Cytogenetics and Cell Genetics. 75: 254-257. PMID 9067436 DOI: 10.1159/000134495  0.34
1996 Smanik PA, Liu Q, Furminger TL, Ryu K, Xing S, Mazzaferri EL, Jhiang SM. Cloning of the human sodium iodide symporter Biochemical and Biophysical Research Communications. 226: 339-345. PMID 8806637 DOI: 10.1006/Bbrc.1996.1358  0.688
1996 Xing S, Smanik PA, Oglesbee MJ, Trosko JE, Mazzaferri EL, Jhiang SM. Characterization of ret oncogenic activation in MEN2 inherited cancer syndromes Endocrinology. 137: 1512-1519. PMID 8612479 DOI: 10.1210/Endo.137.5.8612479  0.418
1996 Jhiang SM, Sagartz JE, Tong Q, Parker-thornburg J, Capen CC, Cho JY, Xing S, Ledent C. Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas Endocrinology. 137: 375-378. PMID 8536638 DOI: 10.1210/Endo.137.1.8536638  0.462
1995 Smanik PA, Furminger TL, Mazzaferri EL, Jhiang SM. Breakpoint characterization of the ret/PTC oncogene in human papillary thyroid carcinoma Human Molecular Genetics. 4: 2313-2318. PMID 8634704 DOI: 10.1093/Hmg/4.12.2313  0.433
1994 Jhiang SM, Smanik PA, Mazzaferri EL. Development of a single-step duplex RT-PCR detecting different forms of ret activation, and identification of the third form of in vivo ret activation in human papillary thyroid carcinoma Cancer Letters. 78: 69-76. PMID 8180971 DOI: 10.1016/0304-3835(94)90033-7  0.424
1994 Jhiang SM, Mazzaferri EL. The ret/PTC oncogene in papillary thyroid carcinoma Journal of Laboratory and Clinical Medicine. 123: 331-337. PMID 8133143  0.31
1994 Smanik PA, Fithian LJ, Jhiang SM. Thyroid Peroxidase Expression and DNA Polymorphisms in Thyroid Cancer Biochemical and Biophysical Research Communications. 198: 948-954. PMID 8117301 DOI: 10.1006/Bbrc.1994.1135  0.428
1994 Mazzaferri EL, Jhiang SM. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer The American Journal of Medicine. 97: 418-428. PMID 7977430 DOI: 10.1016/0002-9343(94)90321-2  0.403
1993 Jhiang SM, Fithian L, Smanik P, McGill J, Tong Q, Mazzaferri EL. Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells1 1 The cDNA sequence of HTAU has been deposited in EMBL Febs Letters. 318: 139-144. PMID 8382624 DOI: 10.1016/0014-5793(93)80008-I  0.385
1992 Jhiang SM, Caruso DR, Gilmore E, Ishizaka Y, Tahira T, Nagao M, Chiu IM, Mazzaferri EL. Detection of the PTC/retTPC oncogene in human thyroid cancers. Oncogene. 7: 1331-7. PMID 1620547  0.352
1988 Jhiang SM, Garey JR, Riggs AF. Exon-intron organization in genes of earthworm and vertebrate globins Science. 240: 334-336. PMID 2832953  0.594
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