Daryl K. Granner, M.D. - Publications

Affiliations: 
Molecular Physiology and Biophysics University of Iowa, Iowa City, IA 
 1984-2008 Department Molecular Physiology & Biophysics Vanderbilt University, Nashville, TN 
Area:
Hormonal regulation of gene expression
Website:
https://medicine.uiowa.edu/physiology/people/emeritus-faculty-members/daryl-granner-md

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Granner DK, Wang JC, Yamamoto KR. Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms. Advances in Experimental Medicine and Biology. 872: 3-31. PMID 26215988 DOI: 10.1007/978-1-4939-2895-8_1  0.662
2015 Granner DK, Wang JC, Yamamoto KR. Regulatory actions of glucocorticoid hormones: From organisms to mechanisms Advances in Experimental Medicine and Biology. 872: 3-31. DOI: 10.1007/978-1-4939-2895-8_1  0.613
2011 Sutherland C, O'Brien R, Granner DK. Genetic Regulation of Glucose Metabolism Comprehensive Physiology. 707-732. DOI: 10.1002/Cphy.Cp070223  0.373
2007 Hall RK, Wang XL, George L, Koch SR, Granner DK. Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect. Molecular Endocrinology (Baltimore, Md.). 21: 550-63. PMID 17095578 DOI: 10.1210/Me.2006-0307  0.463
2007 Phay JE, Oladapupo S, Koch S, Short C, Granner D, Printz RL. Oncogenic H-Ras increases glucose metabolism with an induction of glucose transporter GLUT1 and hexokinase 2 expression Journal of the American College of Surgeons. 205: S89. DOI: 10.1016/J.Jamcollsurg.2007.06.222  0.31
2006 Herzog B, Cardenas J, Hall RK, Villena JA, Budge PJ, Giguère V, Granner DK, Kralli A. Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription. The Journal of Biological Chemistry. 281: 99-106. PMID 16267049 DOI: 10.1074/Jbc.M509276200  0.395
2005 Whitesell RR, Ardehali H, Beechem JM, Powers AC, Van der Meer W, Perriott LM, Granner DK. Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line. The Biochemical Journal. 386: 245-53. PMID 15473866 DOI: 10.1042/Bj20040901  0.606
2004 Wang XL, Herzog B, Waltner-Law M, Hall RK, Shiota M, Granner DK. The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300. The Journal of Biological Chemistry. 279: 34191-200. PMID 15166231 DOI: 10.1074/Jbc.M403455200  0.423
2004 Herzog B, Hall RK, Wang XL, Waltner-Law M, Granner DK. Peroxisome proliferator-activated receptor gamma coactivator-1alpha, as a transcription amplifier, is not essential for basal and hormone-induced phosphoenolpyruvate carboxykinase gene expression. Molecular Endocrinology (Baltimore, Md.). 18: 807-19. PMID 15044597 DOI: 10.1210/Me.2003-0384  0.426
2003 Waltner-Law M, Duong DT, Daniels MC, Herzog B, Wang XL, Prasad R, Granner DK. Elements of the glucocorticoid and retinoic acid response units are involved in cAMP-mediated expression of the PEPCK gene. The Journal of Biological Chemistry. 278: 10427-35. PMID 12531892 DOI: 10.1074/Jbc.M211846200  0.728
2003 Whitesell RR, Ardehali H, Printz RL, Beechem JM, Knobel SM, Piston DW, Granner DK, Van Der Meer W, Perriott LM, May JM. Control of glucose phosphorylation in L6 myotubes by compartmentalization, hexokinase, and glucose transport. The Biochemical Journal. 370: 47-56. PMID 12410639 DOI: 10.1042/Bj20021256  0.614
2002 Onuma H, Osawa H, Yamada K, Ogura T, Tanabe F, Granner DK, Makino H. Identification of the insulin-regulated interaction of phosphodiesterase 3B with 14-3-3 beta protein. Diabetes. 51: 3362-7. PMID 12453887 DOI: 10.2337/Diabetes.51.12.3362  0.364
2002 Kucera T, Waltner-Law M, Scott DK, Prasad R, Granner DK. A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1. The Journal of Biological Chemistry. 277: 26098-102. PMID 12118039 DOI: 10.1074/Jbc.M204013200  0.672
2002 Waltner-Law ME, Wang XL, Law BK, Hall RK, Nawano M, Granner DK. Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. The Journal of Biological Chemistry. 277: 34933-40. PMID 12118006 DOI: 10.1074/Jbc.M204672200  0.399
2002 Duong DT, Waltner-Law ME, Sears R, Sealy L, Granner DK. Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter. The Journal of Biological Chemistry. 277: 32234-42. PMID 12070172 DOI: 10.1074/Jbc.M204873200  0.729
2001 Glorian M, Duplus E, Beale EG, Scott DK, Granner DK, Forest C. A single element in the phosphoenolpyruvate carboxykinase gene mediates thiazolidinedione action specifically in adipocytes Biochimie. 83: 933-943. PMID 11728630 DOI: 10.1016/S0300-9084(01)01343-8  0.687
2001 Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 413: 131-8. PMID 11557972 DOI: 10.1038/35093050  0.66
2001 Monroy MA, Ruhl DD, Xu X, Granner DK, Yaciuk P, Chrivia JC. Regulation of cAMP-responsive element-binding protein-mediated transcription by the SNF2/SWI-related protein, SRCAP. The Journal of Biological Chemistry. 276: 40721-6. PMID 11522779 DOI: 10.1074/Jbc.M103615200  0.356
2001 Davis SN, Geho B, Tate D, Galassetti P, Lau J, Granner D, Mann S. The effects of HDV-insulin on carbohydrate metabolism in Type 1 diabetic patients Journal of Diabetes and Its Complications. 15: 227-233. PMID 11522495 DOI: 10.1016/S1056-8727(01)00154-4  0.334
2001 Stafford JM, Wilkinson JC, Beechem JM, Granner DK. Accessory factors facilitate the binding of glucocorticoid receptor to the phosphoenolpyruvate carboxykinase gene promoter. The Journal of Biological Chemistry. 276: 39885-91. PMID 11518712 DOI: 10.1074/Jbc.M105370200  0.671
2001 Perriott LM, Kono T, Whitesell RR, Knobel SM, Piston DW, Granner DK, Powers AC, May JM. Glucose uptake and metabolism by cultured human skeletal muscle cells: rate-limiting steps. American Journal of Physiology. Endocrinology and Metabolism. 281: E72-80. PMID 11404224 DOI: 10.1152/Ajpendo.2001.281.1.E72  0.342
2001 Stafford JM, Waltner-Law M, Granner DK. Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. The Journal of Biological Chemistry. 276: 3811-9. PMID 11069927 DOI: 10.1074/Jbc.M009389200  0.691
2000 Rucktaschel AK, Granner DK, Christ B. Regulation by glucagon (cAMP) and insulin of the promoter of the human phosphoenolpyruvate carboxykinase gerie (cytosolic) in cultured rat hepatocytes and in human hepatoblastoma cells Biochemical Journal. 352: 211-217. PMID 11062075 DOI: 10.1042/Bj3520211  0.427
2000 Herzog B, Waltner-Law M, Scott DK, Eschrich K, Granner DK. Characterization of the human liver fructose-1,6-bisphosphatase gene promoter Biochemical Journal. 351: 385-392. PMID 11023824 DOI: 10.1042/Bj3510385  0.688
2000 Hall RK, Yamasaki T, Kucera T, Waltner-Law M, O'Brien R, Granner DK. Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins Journal of Biological Chemistry. 275: 30169-30175. PMID 10913147 DOI: 10.1074/Jbc.M004898200  0.438
2000 Waltner-Law M, Daniels MC, Sutherland C, Granner DK. NF-κB inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene Journal of Biological Chemistry. 275: 31847-31856. PMID 10913132 DOI: 10.1074/Jbc.M003656200  0.463
2000 Vogt C, Ardehali H, Iozzo P, Yki-Jarvinen H, Koval J, Maezono K, Pendergrass M, Printz R, Granner D, DeFronzo R, Mandarino L. Regulation of hexokinase II expression in human skeletal muscle in vivo Metabolism: Clinical and Experimental. 49: 814-818. PMID 10877213 DOI: 10.1053/Meta.2000.6245  0.616
2000 Wang JC, Stafford JM, Scott DK, Sutherland C, Granner DK. The molecular physiology of hepatic nuclear factor 3 in the regulation of gluconeogenesis. The Journal of Biological Chemistry. 275: 14717-21. PMID 10799560 DOI: 10.1074/Jbc.275.19.14717  0.797
2000 Wang JC, Waltner-Law M, Yamada K, Osawa H, Stifani S, Granner DK. Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta. The Journal of Biological Chemistry. 275: 18418-23. PMID 10748198 DOI: 10.1074/Jbc.M910211199  0.613
2000 Sugiyama T, Wang JC, Scott DK, Granner DK. Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene Journal of Biological Chemistry. 275: 3446-3454. PMID 10652338 DOI: 10.1074/Jbc.275.5.3446  0.755
1999 Hall RK, Granner DK. Insulin regulates expression of metabolic genes through divergent signaling pathways Journal of Basic and Clinical Physiology and Pharmacology. 10: 119-133. PMID 10444714 DOI: 10.1515/Jbcpp.1999.10.2.119  0.42
1999 Yamada K, Printz RL, Osawa H, Granner DK. Human ZHX1: Cloning, chromosomal location, and interaction with transcription factor NF-Y Biochemical and Biophysical Research Communications. 261: 614-621. PMID 10441475 DOI: 10.1006/Bbrc.1999.1087  0.395
1999 Pierreux CE, Stafford J, Demonte D, Scott DK, Vandenhaute J, O’Brien RM, Granner DK, Rousseau GG, Lemaigre FP. Antiglucocorticoid activity of hepatocyte nuclear factor-6. Proceedings of the National Academy of Sciences of the United States of America. 96: 8961-8966. PMID 10430878 DOI: 10.1073/Pnas.96.16.8961  0.776
1999 Kotani K, Ogawa W, Hino Y, Kitamura T, Ueno H, Sano W, Sutherland C, Granner DK, Kasuga M. Dominant Negative Forms of Akt (Protein Kinase B) and Atypical Protein Kinase Cλ Do Not Prevent Insulin Inhibition of Phosphoenolpyruvate Carboxykinase Gene Transcription Journal of Biological Chemistry. 274: 21305-21312. PMID 10409689 DOI: 10.1074/Jbc.274.30.21305  0.427
1999 Ardehali H, Printz RL, Whitesell RR, May JM, Granner DK. Functional interaction between the N- and C-terminal halves of human hexokinase II Journal of Biological Chemistry. 274: 15986-15989. PMID 10347146 DOI: 10.1074/Jbc.274.23.15986  0.601
1999 Williams CP, Postic C, Robin D, Robin P, Parrinello J, Shelton K, Printz RL, Magnuson MA, Granner DK, Forest C, Chalkley R. Isolation and characterization of the mouse cytosolic phosphoenolpyruvate carboxykinase (GTP) gene: evidence for tissue-specific hypersensitive sites. Molecular and Cellular Endocrinology. 148: 67-77. PMID 10221772 DOI: 10.1016/S0303-7207(98)00234-2  0.403
1999 Wang JC, Strömstedt PE, Sugiyama T, Granner DK. The phosphoenolpyruvate carboxykinase gene glucocorticoid response unit: Identification of the functional domains of accessory factors HNF3β (Hepatic Nuclear Factor-3β) and HNF4 and the necessity of proper alignment of their cognate binding sites Molecular Endocrinology. 13: 604-618. PMID 10194766 DOI: 10.1210/Mend.13.4.0269  0.605
1999 Yamada K, Duong DT, Scott DK, Wang JC, Granner DK. CCAAT/enhancer-binding protein beta is an accessory factor for the glucocorticoid response from the cAMP response element in the rat phosphoenolpyruvate carboxykinase gene promoter. The Journal of Biological Chemistry. 274: 5880-7. PMID 10026211 DOI: 10.1074/Jbc.274.9.5880  0.798
1998 Wang JC, Stafford JM, Granner DK. SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4. The Journal of Biological Chemistry. 273: 30847-50. PMID 9812974 DOI: 10.1074/Jbc.273.47.30847  0.766
1998 Sugiyama T, Scott DK, Wang JC, Granner DK. Structural requirements of the glucocorticoid and retinoic acid response units in the phosphoenolpyruvate carboxykinase gene promoter Molecular Endocrinology. 12: 1487-1498. PMID 9773973 DOI: 10.1210/Mend.12.10.0187  0.735
1998 Scott DK, O'Doherty RM, Stafford JM, Newgard CB, Granner DK. The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism. The Journal of Biological Chemistry. 273: 24145-51. PMID 9727036 DOI: 10.1074/Jbc.273.37.24145  0.756
1998 Yamada K, Wang JC, Osawa H, Scott DK, Granner DK. Efficient large-scale transformation of yeast Biotechniques. 24: 596-600. PMID 9564532 DOI: 10.2144/98244Bm19  0.639
1998 Scott DK, Strömstedt PE, Wang JC, Granner DK. Further characterization of the glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. The role of the glucocorticoid receptor-binding sites Molecular Endocrinology. 12: 482-491. PMID 9544984 DOI: 10.1210/Mend.12.4.0090  0.747
1998 Pendergrass M, Koval J, Vogt C, Yki-Jarvinen H, Iozzo P, Pipek R, Ardehali H, Printz R, Granner D, DeFronzo RA, Mandarino LJ. Insulin-induced hexokinase II expression is reduced in obesity and NIDDM Diabetes. 47: 387-394. PMID 9519744 DOI: 10.2337/Diabetes.47.3.387  0.593
1998 Koval JA, DeFronzo RA, O'Doherty RM, Printz R, Ardehali H, Granner DK, Mandarino LJ. Regulation of hexokinase II activity and expression in human muscle by moderate exercise American Journal of Physiology - Endocrinology and Metabolism. 274. PMID 9486162 DOI: 10.1152/Ajpendo.1998.274.2.E304  0.58
1998 O'Doherty RM, Halseth AE, Granner DK, Bracy DP, Wasserman DH. Analysis of insulin-stimulated skeletal muscle glucose uptake in conscious rat using isotopic glucose analogs American Journal of Physiology - Endocrinology and Metabolism. 274. PMID 9486160 DOI: 10.1152/Ajpendo.1998.274.2.E287  0.344
1998 Vogt C, Yki-jarvinen H, Iozzo P, Pipek R, Pendergrass M, Koval J, Ardehali H, Printz R, Granner D, Defronzo R, Mandarino L. Effects of insulin on subcellular localization of hexokinase II in human skeletal muscle in vivo Journal of Clinical Endocrinology and Metabolism. 83: 230-234. PMID 9435447 DOI: 10.1210/Jc.83.1.230  0.614
1997 Printz RL, Osawa H, Ardehali H, Koch S, Granner DK. Hexokinase II gene: Structure, regulation and promoter organization Biochemical Society Transactions. 25: 107-112. PMID 9056853 DOI: 10.1042/Bst0250107  0.612
1997 Sutherland C, Tebbey PW, Granner DK. Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells Diabetes. 46: 17-22. PMID 8971075 DOI: 10.2337/Diab.46.1.17  0.413
1996 Scott DK, Mitchell JA, Granner DK. The orphan receptor COUP-TF binds to a third glucocorticoid accessory factor element within the phosphoenolpyruvate carboxykinase gene promoter Journal of Biological Chemistry. 271: 31909-31914. PMID 8943235 DOI: 10.1074/Jbc.271.50.31909  0.673
1996 O'Brien RM, Granner DK. Regulation of gene expression by insulin Physiological Reviews. 76: 1109-1161. PMID 8874496 DOI: 10.1152/Physrev.1996.76.4.1109  0.437
1996 O'Doherty RM, Bracy DP, Granner DK, Wasserman DH. Transcription of the rat skeletal muscle hexokinase II gene is increased by acute exercise. Journal of Applied Physiology (Bethesda, Md. : 1985). 81: 789-93. PMID 8872647 DOI: 10.1152/Jappl.1996.81.2.789  0.335
1996 Ardehali H, Tiller GE, Printz RL, Mochizuki H, Prochazka M, Granner DK. A novel (TA)n polymorphism in the hexokinase II gene: Application to noninsulin-dependent diabetes mellitus in the Pima Indians Human Genetics. 97: 482-485. PMID 8834247 DOI: 10.1007/Bf02267071  0.615
1996 Wang JC, Strömstedt PE, O'Brien RM, Granner DK. Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids Molecular Endocrinology. 10: 794-800. PMID 8813720 DOI: 10.1210/Mend.10.7.8813720  0.641
1996 Taylor RW, Printz RL, Armstrong M, Granner DK, Alberti KG, Turnbull DM, Walker M. Variant sequences of the Hexokinase II gene in familial NIDDM. Diabetologia. 39: 322-8. PMID 8721778 DOI: 10.1007/Bf00418348  0.354
1996 Osawa H, Robey RB, Printz RL, Granner DK. Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat hexokinase II gene Journal of Biological Chemistry. 271: 17296-17303. PMID 8663388 DOI: 10.1074/jbc.271.29.17296  0.389
1996 Osawa H, Sutherland C, Robey RB, Printz RL, Granner DK. Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin Journal of Biological Chemistry. 271: 16690-16694. PMID 8663315 DOI: 10.1074/Jbc.271.28.16690  0.422
1996 Sutherland C, O'Brien RM, Granner DK. New connections in the regulation of PEPCK gene expression by insulin. Philosophical Transactions of the Royal Society B. 351: 191-199. PMID 8650266 DOI: 10.1098/Rstb.1996.0016  0.42
1996 Scott DK, Mitchell JA, Granner DK. Identification and characterization of a second retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter Journal of Biological Chemistry. 271: 6260-6264. PMID 8626419 DOI: 10.1074/Jbc.271.11.6260  0.645
1996 Parsa R, Decaux JF, Bossard P, Robey BR, Magnuson MA, Granner DK, Girard J. Induction of the glucokinase gene by insulin in cultured neonatal rat hepatocytes. Relationship with DNase-I hypersensitive sites and functional analysis of a putative insulin-response element. European Journal of Biochemistry. 236: 214-21. PMID 8617267 DOI: 10.1111/J.1432-1033.1996.00214.X  0.431
1996 Gabbay RA, Sutherland C, Gnudi L, Kahn BB, O'Brien RM, Granner DK, Flier JS. Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway Journal of Biological Chemistry. 271: 1890-1897. PMID 8567635 DOI: 10.1074/Jbc.271.4.1890  0.419
1996 Ardehali H, Yano Y, Printz RL, Koch S, Whitesell RR, May JM, Granner DK. Functional organization of mammalian hexokinase II: Retention of catalytic and regulatory functions in both the NH2- and COOH-terminal halves Journal of Biological Chemistry. 271: 1849-1852. PMID 8567628 DOI: 10.1074/Jbc.271.4.1849  0.63
1996 Chang P, Jensen J, Printz RL, Granner DK, Ivy JL, Moller DE. Overexpression of Hexokinase II in Transgenic Mice EVIDENCE THAT INCREASED PHOSPHORYLATION AUGMENTS MUSCLE GLUCOSE UPTAKE Journal of Biological Chemistry. 271: 14834-14839. DOI: 10.1074/Jbc.271.25.14834  0.339
1996 Ardehali H, Whitesell R, Beechern J, Printz R, May J, Granner D. Functional organization of mammalian hexokinase II Faseb Journal. 10.  0.556
1995 Vestergaard H, Bjørbæk C, Hansen T, Larsen FS, Granner DK, Pedersen O. Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients Journal of Clinical Investigation. 96: 2639-2645. PMID 8675629 DOI: 10.1172/Jci118329  0.35
1995 Postic C, Niswender KD, Decaux JF, Parsa R, Shelton KD, Gouhot B, Pettepher CC, Granner DK, Girard J, Magnuson MA. Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites. Genomics. 29: 740-50. PMID 8575768 DOI: 10.1006/Geno.1995.9943  0.421
1995 O'Brien RM, Printz RL, Halmi N, Tiesinga JJ, Granner DK. Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter Bba - Gene Structure and Expression. 1264: 284-288. PMID 8547315 DOI: 10.1016/0167-4781(95)00194-8  0.679
1995 Echwald SM, Bjørbaek C, Hansen T, Clausen JO, Vestergaard H, Zierath JR, Printz RL, Granner DK, Pedersen O. Identification of Four Amino Acid Substitutions in Hexokinase II and Studies of Relationships to NIDDM, Glucose Effectiveness, and Insulin Sensitivity Diabetes. 44: 347-353. PMID 7883123 DOI: 10.2337/Diab.44.3.347  0.373
1995 Vidal-Puig A, Printz RL, Stratton IM, Granner DK, Moller DE. Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142→his substitution Diabetes. 44: 340-346. PMID 7883122 DOI: 10.2337/Diab.44.3.340  0.371
1995 Printz RL, Ardehali H, Koch S, Granner DK. Human hexokinase II mRNA and gene structure Diabetes. 44: 290-294. PMID 7883116 DOI: 10.2337/Diab.44.3.290  0.615
1995 Hall RK, Sladek FM, Granner DK. The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids Proceedings of the National Academy of Sciences of the United States of America. 92: 412-416. PMID 7831301 DOI: 10.1073/Pnas.92.2.412  0.466
1995 Franckhauser S, Antras-Ferry J, Robin P, Robin D, Granner DK, Forest C. Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells: Opposite effects of dexamethasone and isoprenaline on transcription Biochemical Journal. 305: 65-71. PMID 7826355 DOI: 10.1042/Bj3050065  0.432
1995 Sutherland C, O'Brien RM, Granner DK. Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression Journal of Biological Chemistry. 270: 15501-15506. PMID 7797543 DOI: 10.1074/Jbc.270.26.15501  0.422
1995 Whitesell RR, Ward M, McCall AL, Granner DK, May JM. Coupled glucose transport and metabolism in cultured neuronal cells: Determination of the rate-limiting step Journal of Cerebral Blood Flow and Metabolism. 15: 814-826. PMID 7673374 DOI: 10.1038/Jcbfm.1995.102  0.322
1995 Scott DK, Hall RK, Granner DK. Retinoid receptors cause distortion of the retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter Biochemical Journal. 310: 483-490. PMID 7654186 DOI: 10.1042/Bj3100483  0.632
1995 Ardehali H, Printz RL, Koch S, Phillips JA, Granner DK. Isolation, characterization and chromosomal localization of a human pseudogene for hexokinase II Gene. 164: 357-361. PMID 7590357 DOI: 10.1016/0378-1119(95)00449-G  0.583
1995 Osawa H, Printz RL, Whitesell RR, Granner DK. Regulation of hexokinase II gene transcription and glucose phosphorylation by catecholamines, cyclic AMP, and insulin Diabetes. 44: 1426-1432. PMID 7589850 DOI: 10.2337/Diab.44.12.1426  0.413
1995 Williams CP, Granner DK, Magnuson MA, Chalkley R. Cell-Specific Differences in DNase I Hypersensitivity between the Two Promoters of the Rat Glucokinase Gene Biochemical and Biophysical Research Communications. 215: 272-279. PMID 7575601 DOI: 10.1006/Bbrc.1995.2462  0.371
1995 O'Brien RM, Noisin EL, Suwanichkul A, Yamasaki T, Lucas PC, Wang JC, Powell DR, Granner DK. Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes. Molecular and Cellular Biology. 15: 1747-58. PMID 7532283 DOI: 10.1128/Mcb.15.3.1747  0.655
1995 O'Brien RM, Halmi N, Stromstedt PE, Printz RL, Granner DK. Expression cloning of a zinc-finger cyclic AMP-response-element-binding protein Biochemical Journal. 312: 17-21. PMID 7492309 DOI: 10.1042/Bj3120017  0.655
1995 Tebbey PW, Hall RK, Granner DK. The role of the TATA box in the hormonal regulation of phosphoenolpyruvate carboxykinase gene expression Biochemical and Biophysical Research Communications. 215: 1006-1013. PMID 7488024 DOI: 10.1006/Bbrc.1995.2564  0.455
1994 Mitchell J, Noisin E, Hall R, O'Brien R, Imai E, Granner D. Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter Molecular Endocrinology. 8: 585-594. PMID 8058068 DOI: 10.1210/Mend.8.5.8058068  0.44
1994 O'Brien RM, Lucas PC, Yamasaki T, Noisin EL, Granner DK. Potential convergence of insulin and cAMP signal transduction systems at the phosphoenolpyruvate carboxykinase (PEPCK) gene promoter through CCAAT/enhancer binding protein (C/EBP) Journal of Biological Chemistry. 269: 30419-30428. PMID 7982956  0.317
1994 O'Brien RM, Noisin EL, Granner DK. Comparison of the effects of insulin and okadaic acid on phosphoenolpyruvate carboxykinase gene expression Biochemical Journal. 303: 737-742. PMID 7980440 DOI: 10.1042/Bj3030737  0.456
1994 Antras-Ferry J, Franckhauser S, Robin D, Robin P, Granner DK, Forest C. Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells: Effects of retinoic acid and differentiation Biochemical Journal. 302: 943-948. PMID 7945224 DOI: 10.1042/Bj3020943  0.403
1994 Morita H, Yano Y, Niswender KD, May JM, Whitesell RR, Wu L, Printz RL, Granner DK, Magnuson MA, Powers AC. Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. The Journal of Clinical Investigation. 94: 1373-82. PMID 7929812 DOI: 10.1172/Jci117472  0.328
1994 O??Doherty RM, Bracy DP, Granner DK, Wasserman DH. 505 HKII GENE TRANSCRIPTION IS INCREASED BY ACUTE EXERCISE IN RAT SKELETAL MUSCLE Medicine & Science in Sports & Exercise. 26: S90. DOI: 10.1249/00005768-199405001-00506  0.311
1993 Postic C, Leturque A, Rencurel F, Printz RL, Forest C, Granner DK, Girard J. The Effects of Hyperinsulinemia and Hyperglycemia on GLUT4 and Hexokinase II mRNA and Protein in Rat Skeletal Muscle and Adipose Tissue Diabetes. 42: 922-929. PMID 8495814 DOI: 10.2337/Diab.42.6.922  0.305
1993 Imai E, Miner JN, Mitchell JA, Yamamoto KR, Granner DK. Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. The Journal of Biological Chemistry. 268: 5353-6. PMID 8449898  0.612
1993 Faber S, O'Brien RM, Imai E, Granner DK, Chalkley R. Dynamic aspects of DNA/protein interactions in the transcriptional initiation complex and the hormone-responsive domains of the phosphoenolpyruvate carboxykinase promoter in vivo. The Journal of Biological Chemistry. 268: 24976-85. PMID 8227059  0.35
1992 Granner D, O'Brien R, Imai E, Forest C, Mitchell J, Lucas P. Complex hormone response unit regulating transcription of the phosphoenolpyruvate carboxykinase gene: From metabolic pathways to molecular biology Recent Progress in Hormone Research. 47: 319-346. PMID 1745824 DOI: 10.1016/B978-0-12-571147-0.50014-7  0.43
1992 Pilkis SJ, Granner DK. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis Annual Review of Physiology. 54: 885-909. PMID 1562196 DOI: 10.1146/Annurev.Ph.54.030192.004321  0.425
1992 Granner DK, O'Brien RM. Molecular physiology and genetics of NIDDM: Importance of metabolic staging Diabetes Care. 15: 369-395. PMID 1559407 DOI: 10.2337/Diacare.15.3.369  0.354
1992 Hall RK, Scott DK, Noisin EL, Lucas PC, Granner DK. Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex Molecular and Cellular Biology. 12: 5527-5535. PMID 1333043 DOI: 10.1128/Mcb.12.12.5527  0.658
1992 O'Brien RM, Lucas PC, Yamasaki T, Bonovich MT, Forest CD, Granner DK. Insulin and phorbol esters act through the same DNA element to inhibit phosphoenolpyruvate carboxykinase gene transcription. Biochemical Society Transactions. 20: 686-690. PMID 1330786 DOI: 10.1042/Bst0200686  0.425
1992 Lucas PC, Granner DK. Hormone response domains in gene transcription Annual Review of Biochemistry. 61: 1131-1173. PMID 1323234 DOI: 10.1146/Annurev.Bi.61.070192.005411  0.388
1991 Lange AJ, Xu LZ, Poelwijk FV, Lin K, Granner DK, Pilkis SJ. Expression and site-directed mutagenesis of hepatic glucokinase Biochemical Journal. 277: 159-163. PMID 1854332 DOI: 10.1042/Bj2770159  0.334
1991 Lucas PC, O'Brien RM, Mitchell JA, Davis CM, Imai E, Forman BM, Samuels HH, Granner DK. A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene. Proceedings of the National Academy of Sciences of the United States of America. 88: 2184-8. PMID 1848696 DOI: 10.1073/Pnas.88.6.2184  0.448
1991 Faber S, Ip T, Granner D, Chalkley R. The interplay of ubiquitous DNA-binding factors, availability of binding sites in the chromatin, and DNA methylation in the differential regulation of phosphoenolpyruvate carboxykinase gene expression. Nucleic Acids Research. 19: 4681-8. PMID 1716357 DOI: 10.1093/Nar/19.17.4681  0.394
1991 Lucas PC, Forman BM, Samuels HH, Granner DK. Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: Consequences of both retinoic acid and thyroid hormone receptor binding Molecular and Cellular Biology. 11: 5164-5170. PMID 1656224 DOI: 10.1128/Mcb.11.10.5164  0.411
1991 O'Brien RM, Bonovich MT, Forest CD, Granner DK. Signal transduction convergence: Phorbol esters and insulin inhibit phosphoenolpyruvate carboxykinase gene transcription through the same 10-base-pair sequence Proceedings of the National Academy of Sciences of the United States of America. 88: 6580-6584. PMID 1650476 DOI: 10.1073/Pnas.88.15.6580  0.461
1990 O'Brien RM, Granner DK. PEPCK gene as model of inhibitory effects of insulin on gene transcription Diabetes Care. 13: 327-339. PMID 2407480 DOI: 10.2337/Diacare.13.3.327  0.462
1990 Imai E, Stromstedt PE, Quinn PG, Carlstedt-Duke J, Gustafsson J, Granner DK. Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. Molecular and Cellular Biology. 10: 4712-4719. PMID 2388623 DOI: 10.1128/Mcb.10.9.4712  0.459
1990 Ip YT, Poon D, Stone D, Granner DK, Chalkley R. Interaction of a liver-specific factor with an enhancer 4.8 kilobases upstream of the phosphoenolpyruvate carboxykinase gene. Molecular and Cellular Biology. 10: 3770-81. PMID 2355922 DOI: 10.1128/Mcb.10.7.3770  0.438
1990 Forest CD, O'Brien RM, Lucas PC, Magnuson MA, Granner DK. Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequence Molecular Endocrinology. 4: 1302-1310. PMID 2172798 DOI: 10.1210/Mend-4-9-1302  0.462
1990 O'Brien RM, Lucas PC, Forest CD, Magnuson MA, Granner DK. Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription Science. 249: 533-537. PMID 2166335 DOI: 10.1126/Science.2166335  0.457
1990 Quinn PG, Granner DK. Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element Molecular and Cellular Biology. 10: 3357-3364. PMID 2141384 DOI: 10.1128/Mcb.10.7.3357  0.449
1989 Chrapkiewicz NB, Davis CM, Chu DTW, Caldwell CM, Granner DK. Rat gene 33: Analysis of its structure, messenger RNA and basal promoter activity Nucleic Acids Research. 17: 6651-6667. PMID 2780291 DOI: 10.1093/Nar/17.16.6651  0.418
1989 Magnuson MA, Andreone TL, Printz RL, Koch S, Granner DK. Rat glucokinase gene: Structure and regulation by insulin Proceedings of the National Academy of Sciences of the United States of America. 86: 4838-4842. PMID 2662183 DOI: 10.1073/Pnas.86.13.4838  0.479
1989 Ip YT, Granner DK, Chalkley R. Hormonal regulation of phosphoenolpyruvate carboxykinase gene expression is mediated through modulation of an already disrupted chromatin structure. Molecular and Cellular Biology. 9: 1289-97. PMID 2657389 DOI: 10.1128/Mcb.9.3.1289  0.419
1989 Kahn CR, Lauris V, Koch S, Crettaz M, Granner DK. Acute and chronic regulation of phosphoenolpyruvate carboxykinase mRNA by insulin and glucose Molecular Endocrinology. 3: 840-845. PMID 2547157 DOI: 10.1210/Mend-3-5-840  0.364
1988 Petersen DD, Magnuson MA, Granner DK. Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene Molecular and Cellular Biology. 8: 96-104. PMID 3422101 DOI: 10.1128/Mcb.8.1.96  0.411
1988 Quinn PG, Wong TW, Magnuson MA, Shabb JB, Granner DK. Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene. Molecular and Cellular Biology. 8: 3467-75. PMID 2850495 DOI: 10.1128/Mcb.8.8.3467  0.741
1988 Shabb JB, Granner DK. Separation of topoisomerase I activity from the regulatory subunit of type II cyclic adenosine monophosphate-dependent protein kinase. Molecular Endocrinology (Baltimore, Md.). 2: 324-31. PMID 2837663 DOI: 10.1210/Mend-2-4-324  0.709
1988 Sasaki K, Granner DK. Regulation of phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: Reciprocal actions on initiation and elongation Proceedings of the National Academy of Sciences of the United States of America. 85: 2954-2958. PMID 2834722  0.342
1987 Chu DT, Stumpo DJ, Blackshear PJ, Granner DK. The inhibition of phosphoenolpyruvate carboxykinase (guanosine triphosphate) gene expression by insulin is not mediated by protein kinase C Molecular Endocrinology (Baltimore, Md.). 1: 53-59. PMID 3331712 DOI: 10.1210/Mend-1-1-53  0.401
1987 Beebe SJ, Koch SR, Chu DT, Corbin JD, Granner DK. Regulation of phosphoenolpyruvate carboxykinase gene transcription in H4IIE hepatoma cells: evidence for a primary role of the catalytic subunit of 3',5'-cyclic adenosine monophosphate-dependent protein kinase Molecular Endocrinology (Baltimore, Md.). 1: 639-647. PMID 2856413 DOI: 10.1210/Mend-1-9-639  0.592
1987 Magnuson MA, Quinn PG, Granner DK. Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone Journal of Biological Chemistry. 262: 14917-14920. PMID 2822706  0.365
1986 Granner DK, Sasaki K, Andreone T, Beale E. Insulin regulates expression of the phosphoenolpyruvate carboxykinase gene Recent Progress in Hormone Research. 42: 111-141. PMID 3526450 DOI: 10.1016/B978-0-12-571142-5.50007-0  0.435
1986 Granner DK, Sasaki K, Chu D. Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin Annals of the New York Academy of Sciences. 175-190. PMID 3026222 DOI: 10.1111/J.1749-6632.1986.Tb15530.X  0.435
1986 Chu DTW, Granner DK. The effect of phorbol esters and diacylglycerol on expression of the phosphoenolpyruvate carboxykinase (GTP) gene in rat hepatoma H4IIE cells Journal of Biological Chemistry. 261: 16848-16853. PMID 3023368  0.345
1986 Beale EG, Koch SR, Brotherton AFA, Sheorain VS, Granner DK. Insulin decreases H4IIE cell PEPCK mRNA by a mechanism that does not involve cAMP Diabetes. 35: 546-549. PMID 3007246 DOI: 10.2337/Diab.35.5.546  0.41
1985 Granner DK, Andreone TL. Insulin modulation of gene expression Diabetes/Metabolism Reviews. 1: 139-170. PMID 2873003 DOI: 10.1002/Dmr.5610010108  0.372
1985 Granner DK, Beale EG. CHAPTER 4 – Regulation of the Synthesis of Tyrosine Aminotransferase and Phosphoenolpyruvate Carboxykinase by Glucocorticoid Hormones Biochemical Actions of Hormones. 89-138. DOI: 10.1016/B978-0-12-452812-3.50008-7  0.311
1984 Parslow TG, Blair DL, Murphy WJ, Granner DK. Structure of the 5' ends of immunoglobulin genes: A novel conserved sequence Proceedings of the National Academy of Sciences of the United States of America. 81: 2650-2654. PMID 6425835 DOI: 10.1073/Pnas.81.9.2650  0.389
1984 Beale E, Andreone T, Koch S, Granner M, Granner D. Insulin and glucagon regulate cytosolic phosphoenolpyruvate carboxykinase (GTP) mRNA in rat liver Diabetes. 33: 328-332. PMID 6323236 DOI: 10.2337/Diab.33.4.328  0.364
1983 Granner D, Andreone T, Sasaki K, Beale E. Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin Nature. 305: 549-551. PMID 6353247 DOI: 10.1038/305549A0  0.416
1983 Parslow TG, Milburn GL, Lynch RG, Granner DK. Suppressor T cell action inhibits the expression of an excluded immunoglobulin gene Science. 220: 1389-1391. PMID 6222474 DOI: 10.1126/Science.6222474  0.339
1981 Beale EG, Katzen CS, Granner DK. Regulation of rat liver phosphoenolpyruvate carboxykinase (GTP) messenger ribonucleic acid activity by N6,O2'-dibutyryladenosine 3',5'-phosphate Biochemistry. 20: 4878-4883. PMID 6271173 DOI: 10.1021/Bi00520A012  0.345
1980 Schlechte J, Sherman B, Halmi N, VanGilder J, Chapler F, Dolan K, Granner D, Duello T, Harris C. Prolactin-secreting pituitary tumors in amenorrheic women: a comprehensive study Endocrine Reviews. 1: 295-308. PMID 7014211 DOI: 10.1210/Edrv-1-3-295  0.477
1979 Sherman BM, Harris CE, Schlechte J, Duello TM, Halmi NS, Gilder JV, Chapler FK, Granner DK. Pathogenesis of Prolactin-Secreting Pituitary Adenomas Obstetrical & Gynecological Survey. 34: 395-396. DOI: 10.1097/00006254-197905000-00018  0.501
1975 Granner DK, Sellers L, Lee A, Butters C, Kutina L. A comparison of the uptake, metabolism, and action ot cyclic adenine nucleotides in cultured hepatoma cells Archives of Biochemistry and Biophysics. 169: 601-615. PMID 241296 DOI: 10.1016/0003-9861(75)90204-0  0.331
1972 Granner DK, Halmi NS. Lack of positive correlation between adenyl cyclase activity and iodide transport in rat thyroids Endocrinology. 91: 409-414. PMID 4644224 DOI: 10.1210/Endo-91-2-409  0.527
1970 Thompson EB, Granner DK, Tomkins GM. Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells. Journal of Molecular Biology. 54: 159-75. PMID 4395444 DOI: 10.1016/0022-2836(70)90424-9  0.53
1970 Granner DK, Thompson EB, Tomkins GM. Dexamethasone phosphate-induced synthesis of tyrosine aminotransferase in hepatoma tissue culture cells. Studies of the early phases of induction and of the steroid requirement for maintanance of the induced rate of synthesis. The Journal of Biological Chemistry. 245: 1472-8. PMID 4392629  0.484
1970 Granner DK, Tomkins GM. [80] Tyrosine aminotransferase (rat liver) Methods in Enzymology. 17: 633-637. DOI: 10.1016/0076-6879(71)17252-7  0.541
1969 Tomkins GM, Gelehrter TD, Granner D, Martin D, Samuels HH, Thompson EB. Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA. Science (New York, N.Y.). 166: 1474-80. PMID 17655040 DOI: 10.1126/science.166.3912.1474  0.521
1969 Martin D, Tomkins GM, Granner D. Synthesis and induction of tyrosine aminotransferase in synchronized hepatoma cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 62: 248-55. PMID 4388856 DOI: 10.1073/Pnas.62.1.248  0.534
1968 Granner DK, Hayashi S, Thompson EB, Tomkins GM. Stimulation of tyrosine aminotransferase synthesis by dexamethasone phosphate in cell culture. Journal of Molecular Biology. 35: 291-301. PMID 4398833 DOI: 10.1016/S0022-2836(68)80025-7  0.515
1968 Granner D, Chase LR, Aurbach GD, Tomkins GM. Tyrosine aminotransferase: enzyme induction independent of adenosine 3', 5'-monophosphate. Science (New York, N.Y.). 162: 1018-20. PMID 4387000 DOI: 10.1126/Science.162.3857.1018  0.513
1967 Hayashi SI, Granner DK, Tomkins GM. Tyrosine aminotransferase. Purificaton and characterization. The Journal of Biological Chemistry. 242: 3998-4006. PMID 4964828  0.464
1966 Tomkins GM, Thompson EB, Hayashi S, Gelehrter T, Granner D, Peterkofsky B. Tyrosine transaminase induction in mammalian cells in tissue culture. Cold Spring Harbor Symposia On Quantitative Biology. 31: 349-60. PMID 4295324 DOI: 10.1101/Sqb.1966.031.01.045  0.514
1963 GRANNER DK, CURTIS SJ, SCRANTON JR, HALMI NS. Differences in thyroid function between triiodothyroninetreated and hypophysectomized rats: binding glands Endocrinology. 72: 100-105. PMID 13949841  0.536
1962 GRANNER DK, CURTIS SJ, SCRANTON JR, HALMI NS. Differences in thyroid function between triiodothyroninetreated and hypophysectomized rats: blocked glands Endocrinology. 71: 816-821. PMID 13949840 DOI: 10.1210/Endo-71-5-816  0.53
1960 HALMI NS, GRANNER DK, DOUGHMAN DJ, PETERS BH, MULLER G. Biphasic effect of TSH on thyroidal iodide collection in rats Endocrinology. 67: 70-81. PMID 14399138 DOI: 10.1210/Endo-67-1-70  0.518
1960 HALMI NS, GRANNER DK, MULLER G, PETERS BH, SMITH BD. Effect of thiocyanate, stable iodide and perchlorate on the kinetics of radioiodide transport between thyroid gland and blood of rats Endocrinology. 67: 332-336. PMID 13848402 DOI: 10.1210/Endo-67-3-332  0.511
1959 HALMI NS, GRANNER DK, DOUGHMAN DJ, SMITH BD. Response of the thyroidal iodide pump and thyroid weight to goitrogens in rats fed low or high iodine diets Endocrinology. 65: 607-613. PMID 14399137 DOI: 10.1210/Endo-65-4-607  0.508
1959 HALMI NS, GRANNER DK, ALBERT H, DOUGHMAN DJ. Inhibition of thyroidal iodide concentrating by triiodothyronine: evidence for an effect not due to depression of thyrotrophin but dependent on the pituitary Endocrinology. 65: 101-105. PMID 13663854 DOI: 10.1210/Endo-65-1-101  0.503
1959 HALMI NS, ALBERT H, DOUGHMAN DJ, GRANNER DK, SPIRTOS BN. Improved intravenous glucose tolerance in thyroidectomized or hypophysectomized rats treated with triiodothyronine Endocrinology. 64: 618-621. PMID 13639887  0.54
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