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Robert G. Roeder - Publications

Affiliations: 
1971-1982 Washington University School of Medicine, St. Louis, MO, United States 
 1982- Rockefeller University, New York, NY, United States 
Area:
Molecular Biology
Website:
https://www.rockefeller.edu/our-scientists/heads-of-laboratories/895-robert-g-roeder/
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421 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen Q, Wang S, Zhang J, Xie M, Lu B, He J, Zhen Z, Li J, Zhu J, Li R, Li P, Wang H, Vakoc C, Roeder RG, Chen M. JMJD1C forms condensates to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells. Protein & Cell. PMID 39450904 DOI: 10.1093/procel/pwae059  0.344
2024 Zhang S, Roeder RG. Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity. Nature Structural & Molecular Biology. PMID 39251822 DOI: 10.1038/s41594-024-01384-6  0.483
2024 Zhang S, Roeder RG. Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity. Biorxiv : the Preprint Server For Biology. PMID 39211208 DOI: 10.1101/2024.07.25.605008  0.491
2024 Yang Z, Zhang G, Zhao R, Tian T, Zhi J, Wei G, Roeder RG, Jing L, Yu M. MLL-AF9 regulates transcriptional initiation in mixed lineage leukemic cells. The Journal of Biological Chemistry. 107566. PMID 39002676 DOI: 10.1016/j.jbc.2024.107566  0.443
2024 Zhao H, Li J, Xiang Y, Malik S, Vartak SV, Veronezi GMB, Young N, Riney M, Kalchschmidt J, Conte A, Jung SK, Ramachandran S, Roeder RG, Shi Y, Casellas R, et al. An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Molecular Cell. PMID 38955181 DOI: 10.1016/j.molcel.2024.06.006  0.403
2024 Cheng IH, Pi WC, Hsu CH, Guo Y, Lai JL, Wang GG, Chung BC, Roeder RG, Chen WY. TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes. Cell Death Discovery. 10: 244. PMID 38773077 DOI: 10.1038/s41420-024-02017-z  0.426
2024 Lin R, Roeder RG, Barrows D, Mo Y, Onikubo T, Zhang Z. MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression. Biorxiv : the Preprint Server For Biology. PMID 38562677 DOI: 10.1101/2024.03.18.585606  0.842
2023 Crump NT, Smith AL, Godfrey L, Dopico-Fernandez AM, Denny N, Harman JR, Hamley JC, Jackson NE, Chahrour C, Riva S, Rice S, Kim J, Basrur V, Fermin D, Elenitoba-Johnson K, ... Roeder RG, et al. MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia. Nature Communications. 14: 5208. PMID 37626123 DOI: 10.1038/s41467-023-40981-9  0.374
2023 Perlee S, Kikuchi S, Nakadai T, Masuda T, Ohtsuki S, Matsumoto M, Rahmutulla B, Fukuyo M, Cifani P, Kentsis A, Roeder RG, Kaneda A, Hoshii T. SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3. Embo Reports. e57108. PMID 37535603 DOI: 10.15252/embr.202357108  0.43
2023 Malik S, Roeder RG. Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators. Nature Reviews. Genetics. PMID 37532915 DOI: 10.1038/s41576-023-00630-9  0.553
2023 Liu N, Konuma T, Sharma R, Wang D, Zhao N, Cao L, Ju Y, Liu D, Wang S, Bosch A, Sun Y, Zhang S, Ji D, Nagatoishi S, Suzuki N, ... ... Roeder RG, et al. Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin. Molecular Cell. PMID 37311463 DOI: 10.1016/j.molcel.2023.05.022  0.563
2023 Nakadai T, Shimada M, Ito K, Cevher MA, Chu CS, Kumegawa K, Maruyama R, Malik S, Roeder RG. Two target gene activation pathways for orphan ERR nuclear receptors. Cell Research. 33: 165-183. PMID 36646760 DOI: 10.1038/s41422-022-00774-z  0.822
2022 Lyons H, Veettil RT, Pradhan P, Fornero C, De La Cruz N, Ito K, Eppert M, Roeder RG, Sabari BR. Functional partitioning of transcriptional regulators by patterned charge blocks. Cell. PMID 36603581 DOI: 10.1016/j.cell.2022.12.013  0.636
2022 Sun J, Li X, Hou X, Cao S, Cao W, Zhang Y, Song J, Wang M, Wang H, Yan X, Li Z, Roeder RG, Wang W. Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter. Nature Communications. 13: 6871. PMID 36369505 DOI: 10.1038/s41467-022-34639-1  0.543
2022 Chen Q, Cevher MA, Jiang Q, Wang S, Sun X, Roeder RG, Chen M. LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213718119. PMID 36215477 DOI: 10.1073/pnas.2213718119  0.825
2022 Zhang YF, Wang XL, Xu CH, Liu N, Zhang L, Zhang YM, Xie YY, Zhang YL, Huang QH, Wang L, Chen Z, Chen SJ, Roeder RG, Shen S, Xue K, et al. A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation. Frontiers in Cell and Developmental Biology. 10: 992714. PMID 36158200 DOI: 10.3389/fcell.2022.992714  0.519
2022 Chen Z, Ye Z, Soccio RE, Nakadai T, Hankey W, Zhao Y, Huang F, Yuan F, Wang H, Cui Z, Sunkel B, Wu D, Dzeng RK, Thomas-Ahner JM, Huang THM, ... ... Roeder RG, et al. Phosphorylated MED1 links transcription recycling and cancer growth. Nucleic Acids Research. PMID 35394046 DOI: 10.1093/nar/gkac246  0.461
2022 Ren Z, Kim A, Huang YT, Pi WC, Gong W, Yu X, Qi J, Jin J, Cai L, Roeder RG, Chen WY, Wang GG. A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35217626 DOI: 10.1073/pnas.2122940119  0.376
2022 Wang J, Yu X, Gong W, Liu X, Park KS, Ma A, Tsai YH, Shen Y, Onikubo T, Pi WC, Allison DF, Liu J, Chen WY, Cai L, Roeder RG, et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Nature Cell Biology. PMID 35210568 DOI: 10.1038/s41556-022-00850-x  0.798
2021 Leonen CJA, Shimada M, Weller CE, Nakadai T, Hsu PL, Tyson EL, Mishra A, Shelton PMM, Sadilek M, Hawkins RD, Zheng N, Roeder RG, Chatterjee C. Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts. Elife. 10. PMID 34747692 DOI: 10.7554/eLife.67952  0.682
2021 Chen Z, Hankey W, Zhao Y, Groth J, Huang F, Wang H, Campos AR, Huang J, Roeder RG, Wang Q. Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling. Nature Communications. 12: 6318. PMID 34732721 DOI: 10.1038/s41467-021-26604-1  0.441
2021 Doane AS, Chu CS, Di Giammartino DC, Rivas MA, Hellmuth JC, Jiang Y, Yusufova N, Alonso A, Roeder RG, Apostolou E, Melnick AM, Elemento O. OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity. Nature Immunology. PMID 34556886 DOI: 10.1038/s41590-021-01025-w  0.306
2021 Wu A, Zhi J, Tian T, Cihan A, Cevher MA, Liu Z, David Y, Muir TW, Roeder RG, Yu M. DOT1L complex regulates transcriptional initiation in human erythroleukemic cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34187895 DOI: 10.1073/pnas.2106148118  0.804
2021 Ito K, Schneeberger M, Gerber A, Jishage M, Marchildon F, Maganti AV, Cohen P, Friedman JM, Roeder RG. Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues. Genes & Development. PMID 33888560 DOI: 10.1101/gad.346791.120  0.784
2021 Lee YL, Ito K, Pi WC, Lin IH, Chu CS, Malik S, Cheng IH, Chen WY, Roeder RG. Mediator subunit MED1 is required for E2A-PBX1-mediated oncogenic transcription and leukemic cell growth. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33542097 DOI: 10.1073/pnas.1922864118  0.676
2021 Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, Liu X, Xu N, Xue Y, Roeder RG, Maze I, Muir TW, Li H. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526675 DOI: 10.1073/pnas.2016742118  0.317
2020 Jishage M, Roeder RG. Regulation of hepatocyte cell cycle re-entry by RNA polymerase II-associated Gdown1. Cell Cycle (Georgetown, Tex.). 1-9. PMID 33238793 DOI: 10.1080/15384101.2020.1843776  0.368
2020 Chu CS, Hellmuth JC, Singh R, Ying HY, Skrabanek L, Teater MR, Doane AS, Elemento O, Melnick AM, Roeder RG. Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage. Molecular Cell. PMID 33232656 DOI: 10.1016/j.molcel.2020.10.036  0.318
2020 Peiretti F, Montanari R, Capelli D, Bonardo B, Colson C, Amri EZ, Grimaldi M, Balaguer P, Ito K, Roeder RG, Pochetti G, Brunel JM. A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities. Journal of Medicinal Chemistry. 63: 13124-13139. PMID 33142057 DOI: 10.1021/acs.jmedchem.0c01555  0.468
2020 Mashtalir N, Suzuki H, Farrell DP, Sankar A, Luo J, Filipovski M, D'Avino AR, St Pierre R, Valencia AM, Onikubo T, Roeder RG, Han Y, He Y, Ranish JA, DiMaio F, et al. A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms. Cell. PMID 33053319 DOI: 10.1016/j.cell.2020.09.051  0.784
2020 Gerber A, Roeder RG. The CTD Is Not Essential for the Post-Initiation Control of pol II Activity. Journal of Molecular Biology. PMID 32707132 DOI: 10.1016/j.jmb.2020.07.010  0.738
2020 Wang X, Gerber A, Chen WY, Roeder RG. Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development. Proceedings of the National Academy of Sciences of the United States of America. PMID 32576691 DOI: 10.1073/pnas.1922821117  0.715
2020 Jishage M, Ito K, Chu CS, Wang X, Yamaji M, Roeder RG. Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle. Genes & Development. PMID 32381628 DOI: 10.1101/gad.337683.120  0.613
2020 Gerber A, Ito K, Chu CS, Roeder RG. Gene-Specific Control of tRNA Expression by RNA Polymerase II. Molecular Cell. PMID 32298650 DOI: 10.1016/j.molcel.2020.03.023  0.808
2020 Pi WC, Wang J, Shimada M, Lin JW, Geng H, Lee YL, Li D, Wang GG, Roeder RG, Chen WY. E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia. Blood. PMID 32276273 DOI: 10.1182/blood.2019003312  0.358
2020 Williams RT, Guarecuco R, Gates LA, Barrows D, Passarelli MC, Carey B, Baudrier L, Jeewajee S, La K, Prizer B, Malik S, Garcia-Bermudez J, Zhu XG, Cantor J, Molina H, ... ... Roeder RG, et al. ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. Cell Metabolism. 31: 852-861.e6. PMID 32268116 DOI: 10.1016/J.Cmet.2020.03.008  0.666
2020 Mondello P, Tadros S, Teater M, Fontan L, Chang AY, Jain N, Yang H, Singh S, Ying HY, Chu CS, Ma MCJ, Toska E, Alig S, Durant M, de Stanchina E, ... ... Roeder RG, et al. Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma. Cancer Discovery. PMID 31915197 DOI: 10.1158/2159-8290.Cd-19-0116  0.429
2019 Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll TS, Li Y, Feng L, Chen G, Wang SP, Ortiz MV, Daley SK, Wang X, Xuan H, ... ... Roeder RG, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. PMID 31853060 DOI: 10.1038/S41586-019-1842-7  0.368
2019 Zhang D, Tang Z, Huang H, Zhou G, Cui C, Weng Y, Liu W, Kim S, Lee S, Perez-Neut M, Ding J, Czyz D, Hu R, Ye Z, He M, ... ... Roeder RG, et al. Metabolic regulation of gene expression by histone lactylation. Nature. 574: 575-580. PMID 31645732 DOI: 10.1038/S41586-019-1678-1  0.307
2019 Kumari N, Hassan MA, Lu X, Roeder RG, Biswas D. AFF1 acetylation by p300 temporally inhibits transcription during genotoxic stress response. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611376 DOI: 10.1073/pnas.1907097116  0.421
2019 Pham P, Malik S, Mak C, Calabrese PC, Roeder RG, Goodman MF. AID-RNA polymerase II transcription-dependent deamination of IgV DNA. Nucleic Acids Research. PMID 31566237 DOI: 10.1093/nar/gkz821  0.356
2019 Roeder RG. 50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms. Nature Structural & Molecular Biology. PMID 31439941 DOI: 10.1038/s41594-019-0287-x  0.432
2019 Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, ... ... Roeder RG, et al. The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing. Molecular Cell. PMID 31399344 DOI: 10.1016/J.Molcel.2019.06.034  0.454
2019 Fukuoka T, Kawai A, Takahara T, Mori M, Roeder RG, Hasegawa N, Ito M. PML-RARα induces all-trans retinoic acid-dependent transcriptional activation through interaction with MED1. Transcription. PMID 31135261 DOI: 10.1080/21541264.2019.1624467  0.42
2019 Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, et al. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature Communications. 10: 2314. PMID 31127101 DOI: 10.1038/S41467-019-10324-8  0.374
2019 Shimada M, Chen WY, Nakadai T, Onikubo T, Guermah M, Rhodes D, Roeder RG. Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway. Molecular Cell. PMID 30902546 DOI: 10.1016/J.Molcel.2019.02.016  0.801
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, ... ... Roeder RG, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.31
2019 Yadav D, Ghosh K, Basu S, Roeder RG, Biswas D. Multivalent Role of Human TFIID in Recruiting Elongation Components at the Promoter-Proximal Region for Transcriptional Control. Cell Reports. 26: 1303-1317.e7. PMID 30699356 DOI: 10.1016/j.celrep.2019.01.012  0.416
2018 Deng P, Zhou Y, Jiang J, Li H, Tian W, Cao Y, Qin Y, Kim J, Roeder RG, Patel DJ, Wang Z. Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224485 DOI: 10.1073/Pnas.1812256115  0.413
2018 Jishage M, Yu X, Shi Y, Ganesan SJ, Chen WY, Sali A, Chait BT, Asturias FJ, Roeder RG. Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nature Structural & Molecular Biology. 25: 859-867. PMID 30190596 DOI: 10.1038/S41594-018-0118-5  0.369
2018 Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, ... ... Roeder RG, et al. Coactivator condensation at super-enhancers links phase separation and gene control. Science (New York, N.Y.). PMID 29930091 DOI: 10.1126/Science.Aar3958  0.355
2018 Zhang Y, Dallner OS, Nakadai T, Fayzikhodjaeva G, Lu YH, Lazar MA, Roeder RG, Friedman JM. A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891714 DOI: 10.1073/Pnas.1806366115  0.459
2018 Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, ... ... Roeder RG, et al. Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets. Oncogene. PMID 29748621 DOI: 10.1038/S41388-018-0284-2  0.388
2018 Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD. Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation. Molecular Cell. 69: 533. PMID 29395068 DOI: 10.1016/j.molcel.2018.01.013  0.302
2017 Durrieu-Gaillard S, Dumay-Odelot H, Boldina G, Tourasse NJ, Allard D, André F, Macari F, Choquet A, Lagarde P, Drutel G, Leste-Lasserre T, Petitet M, Lesluyes T, Lartigue-Faustin L, Dupuy JW, ... ... Roeder RG, et al. Regulation of RNA polymerase III transcription during transformation of human IMR90 fibroblasts with defined genetic elements. Cell Cycle (Georgetown, Tex.). 1-34. PMID 29171785 DOI: 10.1080/15384101.2017.1405881  0.387
2017 Wang SP, Tang Z, Chen CW, Shimada M, Koche RP, Wang LH, Nakadai T, Chramiec A, Krivtsov AV, Armstrong SA, Roeder RG. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription. Molecular Cell. 67: 308-321.e6. PMID 28732206 DOI: 10.1016/J.Molcel.2017.06.028  0.374
2017 Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, Garzia A, Morozov P, Manickavel S, McFarland HL, Roeder RG, Hafner M, Tuschl T. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. PMID 28297718 DOI: 10.1038/Nature21690  0.341
2016 Minsky N, Roeder RG. Control of secreted protein gene expression and the mammalian secretome by the metabolic regulator PGC-1α. The Journal of Biological Chemistry. PMID 27909049 DOI: 10.1074/jbc.C116.761049  0.337
2016 Malik S, Roeder RG. Mediator: A Drawbridge across the Enhancer-Promoter Divide. Molecular Cell. 64: 433-434. PMID 27814486 DOI: 10.1016/j.molcel.2016.10.024  0.398
2016 Josefowicz SZ, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park HS, Garcia BA, Taunton J, Roeder RG, Allis CD. Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. Molecular Cell. 64: 347-361. PMID 27768872 DOI: 10.1016/J.Molcel.2016.09.026  0.415
2016 Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre Ena X, Teater M, Meydan C, Li Z, Poloway D, Wang S, ... ... Roeder RG, et al. CREBBP Inactivation Promotes the Development of HDAC3 Dependent Lymphomas. Cancer Discovery. PMID 27733359 DOI: 10.1158/2159-8290.Cd-16-0975  0.371
2016 Li Y, Sabari BR, Panchenko T, Wen H, Zhao D, Guan H, Wan L, Huang H, Tang Z, Zhao Y, Roeder RG, Shi X, Allis CD, Li H. Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Molecular Cell. 62: 181-193. PMID 27105114 DOI: 10.1016/J.Molcel.2016.03.028  0.351
2016 Goudarzi A, Zhang D, Huang H, Barral S, Kwon OK, Qi S, Tang Z, Buchou T, Vitte AL, He T, Cheng Z, Montellier E, Gaucher J, Curtet S, Debernardi A, ... ... Roeder RG, et al. Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters. Molecular Cell. 62: 169-180. PMID 27105113 DOI: 10.1016/J.Molcel.2016.03.014  0.335
2016 Hoshii T, Cifani P, Nakadai T, Feng Z, Huang C, Koche R, Delaney CD, Chen CD, Lowe SW, Roeder R, Kentsis A, Armstrong SA. Non-Catalytic Role of SETD1A Regulates DNA Repair in Leukemia Blood. 128: 434-434. DOI: 10.1182/Blood.V128.22.434.434  0.444
2016 Maekawa A, Hasegawa N, Tanaka S, Matsubara L, Imanishi A, Yano M, Roeder R, Asano S, Ito M. Periostin Supports Hematopoietic Stem/Progenitor Cells and Niche-Dependent Myeloblastoma Cells In Vitro Blood. 128: 1494-1494. DOI: 10.1182/Blood.V128.22.1494.1494  0.325
2015 Yu M, Yang W, Ni T, Tang Z, Nakadai T, Zhu J, Roeder RG. RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II. Science (New York, N.Y.). 350: 1383-6. PMID 26659056 DOI: 10.1126/science.aad2338  0.362
2015 Chen M, Zhu N, Liu X, Laurent B, Tang Z, Eng R, Shi Y, Armstrong SA, Roeder RG. JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. Genes & Development. 29: 2123-39. PMID 26494788 DOI: 10.1101/Gad.267278.115  0.348
2015 Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, Li H, Tian Q, Roeder RG, Wang G. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. The Embo Journal. PMID 26330467 DOI: 10.15252/Embj.201591279  0.447
2015 Holt MT, David Y, Pollock S, Tang Z, Jeon J, Kim J, Roeder RG, Muir TW. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26240340 DOI: 10.1073/Pnas.1504483112  0.321
2015 Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD. Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation. Molecular Cell. 58: 203-15. PMID 25818647 DOI: 10.1016/J.Molcel.2015.02.029  0.4
2015 Iida S, Chen W, Nakadai T, Ohkuma Y, Roeder RG. PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1. Genes & Development. 29: 308-21. PMID 25644605 DOI: 10.1101/gad.252809.114  0.411
2014 Roy AL, Roeder RG. Chromatin and transcriptional tango on the immune dance floor. Frontiers in Immunology. 5: 631. PMID 25566246 DOI: 10.3389/Fimmu.2014.00631  0.404
2014 Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, ... ... Roeder RG, et al. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 26: 896-908. PMID 25464900 DOI: 10.1016/J.Ccell.2014.10.009  0.783
2014 Cevher MA, Shi Y, Li D, Chait BT, Malik S, Roeder RG. Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit. Nature Structural & Molecular Biology. 21: 1028-34. PMID 25383669 DOI: 10.1038/Nsmb.2914  0.817
2014 Mizuta S, Minami T, Fujita H, Kaminaga C, Matsui K, Ishino R, Fujita A, Oda K, Kawai A, Hasegawa N, Urahama N, Roeder RG, Ito M. CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 28-51. PMID 24245781 DOI: 10.1111/gtc.12104  0.445
2014 Geng H, Hurtz C, Baumjohann D, Chen Z, Chen W, Ballabio E, Xiao G, Lee J, Deucher A, Qi Z, Huang C, Nahar R, Kweon S, Shojaee S, Chan LN, ... ... Roeder R, et al. Self-Enforcing Feedback Activation Between BCL6 and Tonic Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia Blood. 124: 284-284. DOI: 10.1182/Blood.V124.21.284.284  0.314
2013 Kim K, Lee B, Kim J, Choi J, Kim JM, Xiong Y, Roeder RG, An W. Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation. Cell Reports. 5: 1690-703. PMID 24360965 DOI: 10.1016/J.Celrep.2013.11.038  0.359
2013 Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, ... ... Roeder RG, et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes & Development. 27: 2648-62. PMID 24285714 DOI: 10.1101/Gad.232710.113  0.419
2013 Kim DH, Tang Z, Shimada M, Fierz B, Houck-Loomis B, Bar-Dagen M, Lee S, Lee SK, Muir TW, Roeder RG, Lee JW. Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes. Molecular and Cellular Biology. 33: 4936-46. PMID 24126056 DOI: 10.1128/Mcb.00601-13  0.317
2013 Matsui K, Oda K, Mizuta S, Ishino R, Urahama N, Hasegawa N, Roeder RG, Ito M. Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter. Biochemical and Biophysical Research Communications. 440: 184-9. PMID 24055033 DOI: 10.1016/j.bbrc.2013.09.061  0.358
2013 Jiang H, Lu X, Shimada M, Dou Y, Tang Z, Roeder RG. Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95. Nature Structural & Molecular Biology. 20: 1156-63. PMID 23995757 DOI: 10.1038/nsmb.2656  0.456
2013 Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. H3R42me2a is a histone modification with positive transcriptional effects. Proceedings of the National Academy of Sciences of the United States of America. 110: 14894-9. PMID 23980157 DOI: 10.1073/pnas.1312925110  0.318
2013 Chen WY, Zhang J, Geng H, Du Z, Nakadai T, Roeder RG. A TAF4 coactivator function for E proteins that involves enhanced TFIID binding. Genes & Development. 27: 1596-609. PMID 23873942 DOI: 10.1101/Gad.216192.113  0.315
2013 Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature. 500: 93-7. PMID 23812588 DOI: 10.1038/Nature12287  0.416
2013 Deng C, Li Y, Liang S, Cui K, Salz T, Yang H, Tang Z, Gallagher PG, Qiu Y, Roeder R, Zhao K, Bungert J, Huang S. USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription. Plos Genetics. 9: e1003524. PMID 23754954 DOI: 10.1371/Journal.Pgen.1003524  0.532
2013 Lauberth SM, Nakayama T, Wu X, Ferris AL, Tang Z, Hughes SH, Roeder RG. H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation. Cell. 152: 1021-36. PMID 23452851 DOI: 10.1016/J.Cell.2013.01.052  0.819
2013 Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG, Vakoc CR. Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 3901-6. PMID 23412334 DOI: 10.1073/Pnas.1301045110  0.387
2013 Wilkinson AC, Ballabio E, Geng H, North P, Tapia M, Kerry J, Biswas D, Roeder RG, Allis CD, Melnick A, de Bruijn MF, Milne TA. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Reports. 3: 116-27. PMID 23352661 DOI: 10.1016/J.Celrep.2012.12.016  0.32
2013 Geng H, Hurtz C, Chen Z, Chen W, Ballabio E, Xiao G, Kweon S, Nahar R, Sojaee S, Chan LN, Masouleh BK, Sykes DB, Melnick A, Roeder R, Milne T, et al. Targeting Pre-B Cell Receptor and BCL6 In TCF3-PBX1 B-Lineage Acute Lymphoblastic Leukemia Blood. 122: 349-349. DOI: 10.1182/Blood.V122.21.349.349  0.332
2012 McCullough SD, Xu X, Dent SY, Bekiranov S, Roeder RG, Grant PA. Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 109: 21319-24. PMID 23236151 DOI: 10.1073/Pnas.1218331110  0.338
2012 Zaborowska J, Taylor A, Roeder RG, Murphy S. A novel TBP-TAF complex on RNA polymerase II-transcribed snRNA genes. Transcription. 3: 92-104. PMID 22441827 DOI: 10.4161/trns.19783  0.474
2012 Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular Cell. 45: 330-43. PMID 22325351 DOI: 10.1016/J.Molcel.2011.11.032  0.407
2012 Jishage M, Malik S, Wagner U, Uberheide B, Ishihama Y, Hu X, Chait BT, Gnatt A, Ren B, Roeder RG. Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Molecular Cell. 45: 51-63. PMID 22244332 DOI: 10.1016/J.Molcel.2011.12.014  0.383
2012 Kim H, Kim K, Choi J, Heo K, Baek HJ, Roeder RG, An W. p53 requires an intact C-terminal domain for DNA binding and transactivation. Journal of Molecular Biology. 415: 843-54. PMID 22178617 DOI: 10.1016/J.Jmb.2011.12.001  0.595
2011 Xu M, Sharma P, Pan S, Malik S, Roeder RG, Martinez E. Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription. Genes & Development. 25: 2513-24. PMID 22156211 DOI: 10.1101/gad.177360.111  0.487
2011 Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Proceedings of the National Academy of Sciences of the United States of America. 108: 15751-6. PMID 21896721 DOI: 10.1073/Pnas.1111498108  0.367
2011 Roy AL, Sen R, Roeder RG. Enhancer-promoter communication and transcriptional regulation of Igh. Trends in Immunology. 32: 532-9. PMID 21855411 DOI: 10.1016/J.It.2011.06.012  0.464
2011 Chen W, Roeder RG. Mediator-dependent nuclear receptor function. Seminars in Cell & Developmental Biology. 22: 749-58. PMID 21854863 DOI: 10.1016/j.semcdb.2011.07.026  0.337
2011 Shema E, Kim J, Roeder RG, Oren M. RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. Molecular Cell. 42: 477-88. PMID 21596312 DOI: 10.1016/J.Molcel.2011.03.011  0.462
2011 Ren X, Siegel R, Kim U, Roeder RG. Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication. Molecular Cell. 42: 342-55. PMID 21549311 DOI: 10.1016/j.molcel.2011.04.011  0.358
2011 Kim J, Roeder RG. Nucleosomal H2B ubiquitylation with purified factors. Methods (San Diego, Calif.). 54: 331-8. PMID 21443952 DOI: 10.1016/j.ymeth.2011.03.009  0.424
2011 Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG. Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell. 144: 513-25. PMID 21335234 DOI: 10.1016/J.Cell.2011.01.020  0.33
2011 Deng C, Li Y, Liang S, Salz T, Qiu Y, Roeder R, Zhao K, Bungert J, Huang S. Role of hSET1 Complex in Epigenetic Controls of HoxB4 Expression and Development of Hematopoietic Stem Cells Blood. 118: 212-212. DOI: 10.1182/Blood.V118.21.212.212  0.552
2010 Malik S, Roeder RG. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nature Reviews. Genetics. 11: 761-72. PMID 20940737 DOI: 10.1038/nrg2901  0.495
2010 Dumay-Odelot H, Durrieu-Gaillard S, Da Silva D, Roeder RG, Teichmann M. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Cell Cycle (Georgetown, Tex.). 9: 3687-99. PMID 20890107 DOI: 10.4161/cc.9.18.13203  0.407
2010 Chen W, Zhang X, Birsoy K, Roeder RG. A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 10196-201. PMID 20479251 DOI: 10.1073/Pnas.1005626107  0.604
2010 Jiang P, Hu Q, Ito M, Meyer S, Waltz S, Khan S, Roeder RG, Zhang X. Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 107: 6765-70. PMID 20351249 DOI: 10.1073/Pnas.1001814107  0.317
2010 Park JH, Sun XJ, Roeder RG. The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expression. Molecular and Cellular Biology. 30: 2750-61. PMID 20351180 DOI: 10.1128/MCB.00804-09  0.411
2010 Grøntved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S. MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis. Molecular and Cellular Biology. 30: 2155-69. PMID 20194623 DOI: 10.1128/MCB.01238-09  0.435
2010 Kim J, Guermah M, Roeder RG. The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. Cell. 140: 491-503. PMID 20178742 DOI: 10.1016/j.cell.2009.12.050  0.519
2010 Haurie V, Durrieu-Gaillard S, Dumay-Odelot H, Da Silva D, Rey C, Prochazkova M, Roeder RG, Besser D, Teichmann M. Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation. Proceedings of the National Academy of Sciences of the United States of America. 107: 4176-81. PMID 20154270 DOI: 10.1073/pnas.0914980107  0.362
2010 Wang L, Gural A, Perna F, Sun X, Zhao X, Xu H, Hatlen MA, Huang G, Liu F, Xu H, Deblasio T, Menendez S, Voza F, Roeder R, Nimer S. The Acetylation of AML1-ETO Is Required for Leukemogenesis. Blood. 116: 1588-1588. DOI: 10.1182/Blood.V116.21.1588.1588  0.458
2009 Lee S, Roeder RG, Lee JW. Roles of histone H3-lysine 4 methyltransferase complexes in NR-mediated gene transcription. Progress in Molecular Biology and Translational Science. 87: 343-82. PMID 20374709 DOI: 10.1016/S1877-1173(09)87010-5  0.407
2009 Kim J, Roeder RG. Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast. The Journal of Biological Chemistry. 284: 20582-92. PMID 19531475 DOI: 10.1074/jbc.M109.017442  0.349
2009 Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell. 137: 459-71. PMID 19410543 DOI: 10.1016/J.Cell.2009.02.027  0.446
2009 Fujiki R, Chikanishi T, Hashiba W, Ito H, Takada I, Roeder RG, Kitagawa H, Kato S. GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Nature. 459: 455-9. PMID 19377461 DOI: 10.1038/nature07954  0.33
2009 Guermah M, Kim J, Roeder RG. Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system. Methods (San Diego, Calif.). 48: 353-60. PMID 19272450 DOI: 10.1016/j.ymeth.2009.02.022  0.478
2009 Gamper AM, Kim J, Roeder RG. The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. Molecular and Cellular Biology. 29: 266-80. PMID 18936164 DOI: 10.1128/MCB.00315-08  0.38
2008 Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, Lee SK, Chan L, Roeder RG, Lee JW. Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19229-34. PMID 19047629 DOI: 10.1073/Pnas.0810100105  0.415
2008 Kim JH, Yang CK, Heo K, Roeder RG, An W, Stallcup MR. CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. Molecular Cell. 31: 510-9. PMID 18722177 DOI: 10.1016/J.Molcel.2008.08.001  0.519
2008 Mertens C, Roeder RG. Different functional modes of p300 in activation of RNA polymerase III transcription from chromatin templates. Molecular and Cellular Biology. 28: 5764-76. PMID 18644873 DOI: 10.1128/MCB.01262-07  0.504
2008 McGinty RK, Kim J, Chatterjee C, Roeder RG, Muir TW. Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation. Nature. 453: 812-6. PMID 18449190 DOI: 10.1038/Nature06906  0.546
2008 Woiwode A, Johnson SA, Zhong S, Zhang C, Roeder RG, Teichmann M, Johnson DL. PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex. Molecular and Cellular Biology. 28: 4204-14. PMID 18391023 DOI: 10.1128/Mcb.01912-07  0.46
2008 Gamper AM, Roeder RG. Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage. Molecular and Cellular Biology. 28: 2517-27. PMID 18250150 DOI: 10.1128/MCB.01461-07  0.406
2008 Ge K, Cho YW, Guo H, Hong TB, Guermah M, Ito M, Yu H, Kalkum M, Roeder RG. Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Molecular and Cellular Biology. 28: 1081-91. PMID 18039840 DOI: 10.1128/Mcb.00967-07  0.434
2007 Chen W, Roeder RG. The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation. Nucleic Acids Research. 35: 6161-9. PMID 17827210 DOI: 10.1093/nar/gkm661  0.374
2006 Stumpf M, Waskow C, Krötschel M, van Essen D, Rodriguez P, Zhang X, Guyot B, Roeder RG, Borggrefe T. The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proceedings of the National Academy of Sciences of the United States of America. 103: 18504-9. PMID 17132730 DOI: 10.1073/Pnas.0604494103  0.373
2006 Lee S, Lee DK, Dou Y, Lee J, Lee B, Kwak E, Kong YY, Lee SK, Roeder RG, Lee JW. Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proceedings of the National Academy of Sciences of the United States of America. 103: 15392-7. PMID 17021013 DOI: 10.1073/pnas.0607313103  0.361
2006 Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nature Structural & Molecular Biology. 13: 713-9. PMID 16878130 DOI: 10.1038/Nsmb1128  0.36
2006 Vermeulen M, Walter W, Le Guezennec X, Kim J, Edayathumangalam RS, Lasonder E, Luger K, Roeder RG, Logie C, Berger SL, Stunnenberg HG. A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and Cellular Biology. 26: 5226-36. PMID 16809761 DOI: 10.1128/Mcb.00440-06  0.362
2006 Hu X, Malik S, Negroiu CC, Hubbard K, Velalar CN, Hampton B, Grosu D, Catalano J, Roeder RG, Gnatt A. A Mediator-responsive form of metazoan RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 103: 9506-11. PMID 16769904 DOI: 10.1073/Pnas.0603702103  0.421
2006 Guermah M, Palhan VB, Tackett AJ, Chait BT, Roeder RG. Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell. 125: 275-86. PMID 16630816 DOI: 10.1016/J.Cell.2006.01.055  0.453
2006 Baek HJ, Kang YK, Roeder RG. Human Mediator enhances basal transcription by facilitating recruitment of transcription factor IIB during preinitiation complex assembly. The Journal of Biological Chemistry. 281: 15172-81. PMID 16595664 DOI: 10.1074/Jbc.M601983200  0.781
2006 Doyen CM, An W, Angelov D, Bondarenko V, Mietton F, Studitsky VM, Hamiche A, Roeder RG, Bouvet P, Dimitrov S. Mechanism of polymerase II transcription repression by the histone variant macroH2A. Molecular and Cellular Biology. 26: 1156-64. PMID 16428466 DOI: 10.1128/Mcb.26.3.1156-1164.2006  0.384
2005 Kim J, Hake SB, Roeder RG. The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Molecular Cell. 20: 759-70. PMID 16337599 DOI: 10.1016/j.molcel.2005.11.012  0.433
2005 Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. MLL associates specifically with a subset of transcriptionally active target genes. Proceedings of the National Academy of Sciences of the United States of America. 102: 14765-70. PMID 16199523 DOI: 10.1073/pnas.0503630102  0.479
2005 Park SW, Li G, Lin YP, Barrero MJ, Ge K, Roeder RG, Wei LN. Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. Molecular Cell. 19: 643-53. PMID 16137621 DOI: 10.1016/J.Molcel.2005.08.008  0.378
2005 Zhang X, Krutchinsky A, Fukuda A, Chen W, Yamamura S, Chait BT, Roeder RG. MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Molecular Cell. 19: 89-100. PMID 15989967 DOI: 10.1016/J.Molcel.2005.05.015  0.423
2005 Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 121: 859-72. PMID 15960974 DOI: 10.1016/J.Cell.2005.03.036  0.589
2005 Palhan VB, Chen S, Peng GH, Tjernberg A, Gamper AM, Fan Y, Chait BT, La Spada AR, Roeder RG. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 8472-7. PMID 15932940 DOI: 10.1073/Pnas.0503505102  0.362
2005 Malik S, Roeder RG. Dynamic regulation of pol II transcription by the mammalian Mediator complex Trends in Biochemical Sciences. 30: 256-263. PMID 15896744 DOI: 10.1016/j.tibs.2005.03.009  0.492
2005 Chong JA, Moran MM, Teichmann M, Kaczmarek JS, Roeder R, Clapham DE. TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP. Molecular and Cellular Biology. 25: 2632-43. PMID 15767669 DOI: 10.1128/Mcb.25.7.2632-2643.2005  0.502
2005 Malik S, Baek HJ, Wu W, Roeder RG. Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator. Molecular and Cellular Biology. 25: 2117-29. PMID 15743810 DOI: 10.1128/Mcb.25.6.2117-2129.2005  0.694
2005 Roeder RG. Transcriptional regulation and the role of diverse coactivators in animal cells Febs Letters. 579: 909-915. PMID 15680973 DOI: 10.1016/j.febslet.2004.12.007  0.443
2005 Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 102: 749-54. PMID 15640349 DOI: 10.1073/Pnas.0408836102  0.31
2005 Ito M, Urahama N, Sada A, Yakushijin K, Yamamoto K, Okamura A, Minagawa K, Hato A, Chihara K, Roeder RG, Matsui T. The Role of Transcriptional Coactivator TRAP220/MED1 in Nuclear Receptor-Mediated Myelomonocytic Differentiation. Blood. 106: 2727-2727. DOI: 10.1182/BLOOD.V106.11.2727.2727  0.308
2004 Angelov D, Verdel A, An W, Bondarenko V, Hans F, Doyen CM, Studitsky VM, Hamiche A, Roeder RG, Bouvet P, Dimitrov S. SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays. The Embo Journal. 23: 3815-24. PMID 15372075 DOI: 10.1038/Sj.Emboj.7600400  0.307
2004 An W, Kim J, Roeder RG. Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53. Cell. 117: 735-48. PMID 15186775 DOI: 10.1016/J.Cell.2004.05.009  0.327
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, ... ... Roeder RG, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/J.Molcel.2004.05.011  0.791
2004 Weser S, Gruber C, Hafner HM, Teichmann M, Roeder RG, Seifart KH, Meissner W. Transcription factor (TF)-like nuclear regulator, the 250-kDa form of Homo sapiens TFIIIB", is an essential component of human TFIIIC1 activity. The Journal of Biological Chemistry. 279: 27022-9. PMID 15096501 DOI: 10.1074/jbc.M312790200  0.379
2004 Jiang C, Ito M, Piening V, Bruck K, Roeder RG, Xiao H. TIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcription. The Journal of Biological Chemistry. 279: 27781-9. PMID 15073177 DOI: 10.1074/Jbc.M401809200  0.33
2004 Thompson PR, Wang D, Wang L, Fulco M, Pediconi N, Zhang D, An W, Ge Q, Roeder RG, Wong J, Levrero M, Sartorelli V, Cotter RJ, Cole PA. Regulation of the p300 HAT domain via a novel activation loop. Nature Structural & Molecular Biology. 11: 308-15. PMID 15004546 DOI: 10.1038/Nsmb740  0.314
2004 An W, Roeder RG. Reconstitution and transcriptional analysis of chromatin in vitro. Methods in Enzymology. 377: 460-74. PMID 14979045 DOI: 10.1016/S0076-6879(03)77030-X  0.412
2004 Wang S, Ge K, Roeder RG, Hankinson O. Role of mediator in transcriptional activation by the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 279: 13593-600. PMID 14729673 DOI: 10.1074/Jbc.M312274200  0.438
2004 Borggrefe T, Waskow C, Roeder RG, Stumpf M. Severely Impaired Erythropoiesis in Mice Lacking Mediator Subunit Med1/TRAP220. Blood. 104: 1611-1611. DOI: 10.1182/BLOOD.V104.11.1611.1611  0.302
2003 Guermah M, Ge K, Chiang CM, Roeder RG. The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. Molecular Cell. 12: 991-1001. PMID 14580349 DOI: 10.1016/S1097-2765(03)00396-4  0.325
2003 Wang H, An W, Cao R, Xia L, Erdjument-Bromage H, Chatton B, Tempst P, Roeder RG, Zhang Y. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Molecular Cell. 12: 475-87. PMID 14536086 DOI: 10.1016/J.Molcel.2003.08.007  0.361
2003 Hosohata K, Li P, Hosohata Y, Qin J, Roeder RG, Wang Z. Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription. Molecular and Cellular Biology. 23: 7019-29. PMID 12972618 DOI: 10.1128/MCB.23.19.7019-7029.2003  0.329
2003 Zakharova N, Lymar ES, Yang E, Malik S, Zhang JJ, Roeder RG, Darnell JE. Distinct transcriptional activation functions of STAT1alpha and STAT1beta on DNA and chromatin templates. The Journal of Biological Chemistry. 278: 43067-73. PMID 12939262 DOI: 10.1074/jbc.M308166200  0.418
2003 Zheng L, Roeder RG, Luo Y. S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell. 114: 255-66. PMID 12887926 DOI: 10.1016/S0092-8674(03)00552-X  0.389
2003 Gwack Y, Baek HJ, Nakamura H, Lee SH, Meisterernst M, Roeder RG, Jung JU. Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation. Molecular and Cellular Biology. 23: 2055-67. PMID 12612078 DOI: 10.1128/Mcb.23.6.2055-2067.2003  0.66
2003 Kamada K, Roeder RG, Burley SK. Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF. Proceedings of the National Academy of Sciences of the United States of America. 100: 2296-9. PMID 12591941 DOI: 10.1073/Pnas.262798199  0.392
2003 Leach KM, Vieira KF, Kang SH, Aslanian A, Teichmann M, Roeder RG, Bungert J. Characterization of the human beta-globin downstream promoter region. Nucleic Acids Research. 31: 1292-301. PMID 12582249 DOI: 10.1093/Nar/Gkg209  0.324
2003 Goo YH, Sohn YC, Kim DH, Kim SW, Kang MJ, Jung DJ, Kwak E, Barlev NA, Berger SL, Chow VT, Roeder RG, Azorsa DO, Meltzer PS, Suh PG, Song EJ, et al. Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Molecular and Cellular Biology. 23: 140-9. PMID 12482968 DOI: 10.1128/Mcb.23.1.140-149.2003  0.395
2003 Estable MC, Naghavi MH, Kato H, Xiao H, Qin J, Vahlne A, Roeder RG. MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein. Journal of Biomedical Science. 9: 234-45. PMID 12065898 DOI: 10.1007/BF02256070  0.328
2003 Malik S, Roeder RG. Regulation of Basal Transcription by RNA Polymerase II Handbook of Cell Signaling. 3: 11-19. DOI: 10.1016/B978-012124546-7/50633-1  0.41
2002 Wallberg AE, Pedersen K, Lendahl U, Roeder RG. p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Molecular and Cellular Biology. 22: 7812-9. PMID 12391150 DOI: 10.1128/MCB.22.22.7812-7819.2002  0.352
2002 Murphy C, Wang Z, Roeder RG, Gall JG. RNA polymerase III in Cajal bodies and lampbrush chromosomes of the Xenopus oocyte nucleus. Molecular Biology of the Cell. 13: 3466-76. PMID 12388750 DOI: 10.1091/mbc.E02-05-0281  0.382
2002 Casellas R, Jankovic M, Meyer G, Gazumyan A, Luo Y, Roeder R, Nussenzweig M. OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes. Cell. 110: 575-85. PMID 12230975 DOI: 10.1016/S0092-8674(02)00911-X  0.378
2002 Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 99: 10353-8. PMID 12149480 DOI: 10.1073/Pnas.162424199  0.356
2002 Zhou R, Bonneaud N, Yuan CX, de Santa Barbara P, Boizet B, Schomber T, Scherer G, Roeder RG, Poulat F, Berta P, Tibor S. SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. Nucleic Acids Research. 30: 3245-52. PMID 12136106 DOI: 10.1093/NAR/GKF443  0.371
2002 Malik S, Wallberg AE, Kang YK, Roeder RG. TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Molecular and Cellular Biology. 22: 5626-37. PMID 12101254  0.665
2002 Ito M, Okano HJ, Darnell RB, Roeder RG. The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development Embo Journal. 21: 3464-3475. PMID 12093747 DOI: 10.1093/emboj/cdf348  0.616
2002 An W, Palhan VB, Karymov MA, Leuba SH, Roeder RG. Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin. Molecular Cell. 9: 811-21. PMID 11983172 DOI: 10.1016/S1097-2765(02)00497-5  0.351
2002 Baek HJ, Malik S, Qin J, Roeder RG. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Molecular and Cellular Biology. 22: 2842-52. PMID 11909976 DOI: 10.1128/Mcb.22.8.2842-2852.2002  0.687
2002 Kang YK, Guermah M, Yuan CX, Roeder RG. The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. Proceedings of the National Academy of Sciences of the United States of America. 99: 2642-7. PMID 11867769 DOI: 10.1073/pnas.261715899  0.559
2002 Kato H, Tjernberg A, Zhang W, Krutchinsky AN, An W, Takeuchi T, Ohtsuki Y, Sugano S, de Bruijn DR, Chait BT, Roeder RG. SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. The Journal of Biological Chemistry. 277: 5498-505. PMID 11734557 DOI: 10.1074/Jbc.M108702200  0.37
2001 Guermah M, Tao Y, Roeder RG. Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription. Molecular and Cellular Biology. 21: 6882-94. PMID 11564872 DOI: 10.1128/MCB.21.20.6882-6894.2001  0.327
2001 Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Molecular and Cellular Biology. 21: 6782-95. PMID 11564863 DOI: 10.1128/Mcb.21.20.6782-6795.2001  0.67
2001 Purrello M, Pietro CD, Rapisarda A, Amico V, Giunta V, Engel H, Stevens S, Hsieh Y, Teichman M, Wang Z, Sichel G, Roeder R, Grzeschik K. Genes for human general transcription initiation factors TFIIIB, TFIIIB-associated proteins, TFIIIC2 and PTF/SNAPC: functional and positional candidates for tumour predisposition or inherited genetic diseases? Oncogene. 20: 4877-4883. PMID 11521199 DOI: 10.1038/Sj.Onc.1204604  0.465
2001 Yu X, Li P, Roeder RG, Wang Z. Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split. Molecular and Cellular Biology. 21: 4614-25. PMID 11416139 DOI: 10.1128/MCB.21.14.4614-4625.2001  0.346
2001 Zhang D, Penttila TL, Morris PL, Teichmann M, Roeder RG. Spermiogenesis deficiency in mice lacking the Trf2 gene. Science (New York, N.Y.). 292: 1153-5. PMID 11352070 DOI: 10.1126/science.1059188  0.382
2001 Ito M, Roeder RG. The TRAP/SMCC/Mediator complex and thyroid hormone receptor function. Trends in Endocrinology and Metabolism: Tem. 12: 127-34. PMID 11306338 DOI: 10.1016/S1043-2760(00)00355-6  0.339
2000 Teichmann M, Wang Z, Roeder RG. A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. Proceedings of the National Academy of Sciences of the United States of America. 97: 14200-5. PMID 11121026 DOI: 10.1073/pnas.97.26.14200  0.467
2000 Wang Z, Bai L, Hsieh YJ, Roeder RG. Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. The Embo Journal. 19: 6823-32. PMID 11118217 DOI: 10.1093/emboj/19.24.6823  0.406
2000 Kundu TK, Palhan VB, Wang Z, An W, Cole PA, Roeder RG. Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. Molecular Cell. 6: 551-61. PMID 11030335 DOI: 10.1016/S1097-2765(00)00054-X  0.606
2000 Lau OD, Kundu TK, Soccio RE, Ait-Si-Ali S, Khalil EM, Vassilev A, Wolffe AP, Nakatani Y, Roeder RG, Cole PA. HATs off: Selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF Molecular Cell. 5: 589-595. PMID 10882143 DOI: 10.1016/S1097-2765(00)80452-9  0.679
2000 Ito M, Yuan CX, Okano HJ, Darnell RB, Roeder RG. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Molecular Cell. 5: 683-93. PMID 10882104 DOI: 10.1016/S1097-2765(00)80247-6  0.535
2000 Castaño E, Gross P, Wang Z, Roeder RG, Oelgeschläger T. The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts. Proceedings of the National Academy of Sciences of the United States of America. 97: 7184-9. PMID 10852970 DOI: 10.1073/PNAS.140202297  0.493
2000 Malik S, Roeder RG. Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells Trends in Biochemical Sciences. 25: 277-283. PMID 10838567 DOI: 10.1016/S0968-0004(00)01596-6  0.473
2000 Knutson A, Castaño E, Oelgeschläger T, Roeder RG, Westin G. Downstream promoter sequences facilitate the formation of a specific transcription factor IID-promoter complex topology required for efficient transcription from the megalin/low density lipoprotein receptor-related protein 2 promoter Journal of Biological Chemistry. 275: 14190-14197. PMID 10799495 DOI: 10.1074/jbc.275.19.14190  0.39
2000 Xiao H, Palhan V, Yang Y, Roeder RG. TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes. The Embo Journal. 19: 956-63. PMID 10698937 DOI: 10.1093/Emboj/19.5.956  0.373
2000 Makino Y, Yogosawa S, Kayukawa K, Coin F, Egly JM, Wang Zx, Roeder RG, Yamamoto K, Muramatsu M, Tamura Ta. TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism. Molecular and Cellular Biology. 19: 7951-60. PMID 10567521 DOI: 10.1128/Mcb.19.12.7951  0.48
1999 Teichmann M, Wang Z, Martinez E, Tjernberg A, Zhang D, Vollmer F, Chait BT, Roeder RG. Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 13720-5. PMID 10570139 DOI: 10.1073/Pnas.96.24.13720  0.468
1999 Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG. The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity. Molecular and Cellular Biology. 19: 7697-704. PMID 10523658 DOI: 10.1128/MCB.19.11.7697  0.659
1999 Kimura H, Tao Y, Roeder RG, Cook PR. Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure. Molecular and Cellular Biology. 19: 5383-92. PMID 10409729 DOI: 10.1128/Mcb.19.8.5383  0.416
1999 Hsieh YJ, Wang Z, Kovelman R, Roeder RG. Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III. Molecular and Cellular Biology. 19: 4944-52. PMID 10373544 DOI: 10.1128/MCB.19.7.4944  0.441
1999 Pombo A, Jackson DA, Hollinshead M, Wang Z, Roeder RG, Cook PR. Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III. The Embo Journal. 18: 2241-53. PMID 10205177 DOI: 10.1093/Emboj/18.8.2241  0.428
1999 Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J, Roeder RG. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Molecular Cell. 3: 361-70. PMID 10198638 DOI: 10.1016/S1097-2765(00)80463-3  0.349
1999 Gu W, Malik S, Ito M, Yuan CX, Fondell JD, Zhang X, Martinez E, Qin J, Roeder RG. A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Molecular Cell. 3: 97-108. PMID 10024883 DOI: 10.1016/S1097-2765(00)80178-1  0.431
1999 Xiao H, Tao Y, Roeder RG. The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex. The Journal of Biological Chemistry. 274: 3937-40. PMID 9933582 DOI: 10.1074/Jbc.274.7.3937  0.4
1999 Kundu TK, Wang Z, Roeder RG. Human TFIIIC relieves chromatin-mediated repression of RNA polymerase III transcription and contains an intrinsic histone acetyltransferase activity. Molecular and Cellular Biology. 19: 1605-15. PMID 9891093 DOI: 10.1128/MCB.19.2.1605  0.702
1999 Parada CA, Roeder RG. A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription Embo Journal. 18: 3688-3701. DOI: 10.1093/emboj/18.13.3688  0.383
1998 Roeder RG. Role of general and gene-specific cofactors in the regulation of eukaryotic transcription Cold Spring Harbor Symposia On Quantitative Biology. 63: 201-218. PMID 10384284 DOI: 10.1101/SQB.1998.63.201  0.419
1998 Ge H, Si Y, Roeder RG. Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation Embo Journal. 17: 6723-6729. PMID 9822615 DOI: 10.1093/emboj/17.22.6723  0.389
1998 Martinez E, Ge H, Tao Y, Yuan CX, Palhan V, Roeder RG. Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex. Molecular and Cellular Biology. 18: 6571-83. PMID 9774672 DOI: 10.1128/MCB.18.11.6571  0.496
1998 Lin Y, Tang H, Nomura T, Dorjsuren D, Hayashi N, Wei W, Ohta T, Roeder R, Murakami S. The Hepatitis B Virus X Protein Is a Co-activator of Activated Transcription That Modulates the Transcription Machinery and Distal Binding Activators Journal of Biological Chemistry. 273: 27097-27103. PMID 9765226 DOI: 10.1074/Jbc.273.42.27097  0.52
1998 Burley SK, Roeder RG. TATA box mimicry by TFIID: Autoinhibition of pol II transcription Cell. 94: 551-553. PMID 9741619 DOI: 10.1016/S0092-8674(00)81596-2  0.365
1998 Martinez E, Kundu TK, Fu J, Roeder RG. A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID. The Journal of Biological Chemistry. 273: 23781-5. PMID 9726987 DOI: 10.1074/jbc.273.37.23781  0.589
1998 Okamoto T, Yamamoto S, Watanabe Y, Ohta T, Hanaoka F, Roeder RG, Ohkuma Y. Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit. The Journal of Biological Chemistry. 273: 19866-76. PMID 9677423 DOI: 10.1074/jbc.273.31.19866  0.452
1998 Oelgeschläger T, Tao Y, Kang YK, Roeder RG. Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs. Molecular Cell. 1: 925-31. PMID 9660976  0.693
1998 Wang Z, Roeder RG. DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III Molecular Cell. 1: 749-757. PMID 9660958 DOI: 10.1016/S1097-2765(00)80074-X  0.489
1998 Guermah M, Malik S, Roeder RG. Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1. Molecular and Cellular Biology. 18: 3234-44. PMID 9584164 DOI: 10.1128/MCB.18.6.3234  0.394
1998 Purrello M, Pietro CD, Viola A, Rapisarda A, Stevens S, Guermah M, Tao Y, Bonaiuto C, Arcidiacono A, Messina A, Sichel G, Grzeschik K-, Roeder R. Genomics and transcription analysis of human TFIID. Oncogene. 16: 1633-1638. PMID 9569032 DOI: 10.1038/Sj.Onc.1201673  0.499
1998 Pombo A, Cuello P, Schul W, Yoon JB, Roeder RG, Cook PR, Murphy S. Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle. The Embo Journal. 17: 1768-78. PMID 9501098 DOI: 10.1093/Emboj/17.6.1768  0.365
1998 Malik S, Guermah M, Roeder RG. A dynamic model for PC4 coactivator function in RNA polymerase II transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 2192-7. PMID 9482861 DOI: 10.1073/PNAS.95.5.2192  0.464
1998 Xiao H, Tao Y, Greenblatt J, Roeder RG. A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 2146-51. PMID 9482853 DOI: 10.1073/Pnas.95.5.2146  0.458
1998 Lee DK, Wang KC, Roeder RG. Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II. Nucleic Acids Research. 25: 4338-45. PMID 9336466 DOI: 10.1093/NAR/25.21.4338  0.416
1997 Roy AL, Du H, Gregor PD, Novina CD, Martinez E, Roeder RG. Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1 Embo Journal. 16: 7091-7104. PMID 9384587 DOI: 10.1093/Emboj/16.23.7091  0.3
1997 Inamotc S, Segil N, Pan ZQ, Kimura M, Roeder RG. The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of Octamer transcription factors Journal of Biological Chemistry. 272: 29852-29858. PMID 9368058 DOI: 10.1074/Jbc.272.47.29852  0.319
1997 Kundu M, Guermah M, Roeder RG, Amini S, Khalili K. Interaction between cell cycle regulator, E2F-1, and NF-kappaB mediates repression of HIV-1 gene transcription. The Journal of Biological Chemistry. 272: 29468-74. PMID 9368006 DOI: 10.1074/Jbc.272.47.29468  0.558
1997 Wang Z, Luo T, Roeder RG. Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition. Genes & Development. 11: 2371-82. PMID 9308965 DOI: 10.1101/GAD.11.18.2371  0.415
1997 Hoffmann A, Oelgeschläger T, Roeder RG. Considerations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions? Proceedings of the National Academy of Sciences of the United States of America. 94: 8928-35. PMID 9256411 DOI: 10.1073/Pnas.94.17.8928  0.64
1997 Vilalta A, Trivedi A, Wang Z, Roeder RG, Johnson DL. An RNA polymerase III-defective mutation in TATA-binding protein disrupts its interaction with a transcription factor IIIB subunit in drosophila cells. The Journal of Biological Chemistry. 272: 18087-92. PMID 9218440 DOI: 10.1074/Jbc.272.29.18087  0.4
1997 Gu W, Shi XL, Roeder RG. Synergistic activation of transcription by CBP and p53. Nature. 387: 819-23. PMID 9194564 DOI: 10.1038/42972  0.373
1997 Wang Z, Roeder RG. Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation Genes and Development. 11: 1315-1326. PMID 9171375 DOI: 10.1101/GAD.11.10.1315  0.45
1997 Chu WM, Wang Z, Roeder RG, Schmid CW. RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. The Journal of Biological Chemistry. 272: 14755-61. PMID 9169441 DOI: 10.1074/jbc.272.23.14755  0.448
1997 Suzuki-Yagawa Y, Guermah M, Roeder RG. The ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature. Molecular and Cellular Biology. 17: 3284-94. PMID 9154827 DOI: 10.1128/MCB.17.6.3284  0.4
1997 Meisterernst M, Stelzer G, Roeder RG. Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro. Proceedings of the National Academy of Sciences of the United States of America. 94: 2261-5. PMID 9122182 DOI: 10.1073/PNAS.94.6.2261  0.434
1997 Tao Y, Guermah M, Martinez E, Oelgeschläger T, Hasegawa S, Takada R, Yamamoto T, Horikoshi M, Roeder RG. Specific interactions and potential functions of human TAFII100. The Journal of Biological Chemistry. 272: 6714-21. PMID 9045704 DOI: 10.1074/jbc.272.10.6714  0.407
1997 Nishikawa J, Kokubo T, Horikoshi M, Roeder RG, Nakatani Y. Drosophila TAF(II)230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 94: 85-90. PMID 8990165 DOI: 10.1073/PNAS.94.1.85  0.332
1996 Wang Z, Roeder RG. TFIIIC1 acts through a downstream region to stabilize TFIIIC2 binding to RNA polymerase III promoters Molecular and Cellular Biology. 16: 6841-6850. PMID 8943339 DOI: 10.1128/MCB.16.12.6841  0.382
1996 Parada CA, Roeder RG. Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain Nature. 384: 375-378. PMID 8934526 DOI: 10.1038/384375a0  0.397
1996 Ge H, Martinez E, Chiang CM, Roeder RG. Activator-dependent transcription by mammalian RNA polymerase II: In vitro reconstitution with general transcription factors and cofactors Methods in Enzymology. 274: 57-71. PMID 8902796 DOI: 10.1016/S0076-6879(96)74008-9  0.448
1996 Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192 DOI: 10.1101/Gad.10.19.2389  0.73
1996 Bai L, Wang Z, Yoon JB, Roeder RG. Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III. Molecular and Cellular Biology. 16: 5419-26. PMID 8816454 DOI: 10.1128/MCB.16.10.5419  0.44
1996 Burley SK, Roeder RG. Biochemistry and structural biology of transcription factor IID (TFIID) Annual Review of Biochemistry. 65: 769-799. PMID 8811195 DOI: 10.1146/Annurev.Bi.65.070196.004005  0.505
1996 Roeder RG. Nuclear RNA polymerases: Role of general initiation factors and cofactors in eukaryotic transcription Methods in Enzymology. 273: 165-171. PMID 8791609 DOI: 10.1016/S0076-6879(96)73016-1  0.389
1996 Clemens KE, Piras G, Radonovich MF, Choi KS, Duvall JF, DeJong J, Roeder R, Brady JN. Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA. Molecular and Cellular Biology. 16: 4656-64. PMID 8756622 DOI: 10.1128/Mcb.16.9.4656  0.493
1996 Oelgeschlager T, Chiang CM, Roeder RG. Topology and reorganization of a human TFIID-promoter complex Nature. 382: 735-738. PMID 8751448 DOI: 10.1038/382735A0  0.425
1996 Hoffmann A, Roeder RG. Cloning and characterization of human TAF20/15. Multiple interactions suggest a central role in TFIID complex formation. The Journal of Biological Chemistry. 271: 18194-202. PMID 8663456 DOI: 10.1074/Jbc.271.30.18194  0.592
1996 Kawakami K, Masuda K, Nagano K, Ohkuma Y, Roeder RG. Characterization of the core promoter of the Na+/K(+)-ATPase alpha 1 subunit gene. Elements required for transcription by RNA polymerase II and RNA polymerase III in vitro. European Journal of Biochemistry. 237: 440-6. PMID 8647083 DOI: 10.1111/J.1432-1033.1996.0440K.X  0.432
1996 Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK. Crystal structure of a human TATA box-binding protein/TATA element complex. Proceedings of the National Academy of Sciences of the United States of America. 93: 4862-7. PMID 8643494 DOI: 10.1073/Pnas.93.10.4862  0.36
1996 Hoffmann A, Chiang CM, Oelgeschläger T, Xie X, Burley SK, Nakatani Y, Roeder RG. A histone octamer-like structure within TFIID. Nature. 380: 356-9. PMID 8598932 DOI: 10.1038/380356A0  0.616
1996 Xie X, Kokubo T, Cohen SL, Mirza UA, Hoffmann A, Chait BT, Roeder RG, Nakatani Y, Burley SK. Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature. 380: 316-22. PMID 8598927 DOI: 10.1038/380316A0  0.481
1996 Bellorini M, Dantonel JC, Yoon JB, Roeder RG, Tora L, Mantovani R. The major histocompatibility complex class II Ea promoter requires TFIID binding to an initiator sequence. Molecular and Cellular Biology. 16: 503-12. PMID 8552077 DOI: 10.1128/MCB.16.2.503  0.32
1996 Yoon JB, Roeder RG. Cloning of two proximal sequence element-binding transcription factor subunits (γ and δ) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein Molecular and Cellular Biology. 16: 1-9. PMID 8524284 DOI: 10.1128/MCB.16.1.1  0.511
1996 ROEDER R. The role of general initiation factors in transcription by RNA polymerase II Trends in Biochemical Sciences. 21: 327-335. DOI: 10.1016/S0968-0004(96)10050-5  0.385
1995 Martinez E, Zhou Q, L'Etoile ND, Oelgeschläger T, Berk AJ, Roeder RG. Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding Proceedings of the National Academy of Sciences of the United States of America. 92: 11864-11868. PMID 8524864 DOI: 10.1073/Pnas.92.25.11864  0.458
1995 Yoon JB, Murphy S, Bai L, Wang Z, Roeder RG. Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes. Molecular and Cellular Biology. 15: 2019-27. PMID 7891697 DOI: 10.1128/MCB.15.4.2019  0.51
1995 Parada CA, Yoon JB, Roeder RG. A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro. The Journal of Biological Chemistry. 270: 2274-83. PMID 7836461 DOI: 10.1074/JBC.270.5.2274  0.301
1995 Chiang CM, Roeder RG. Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators Science. 267: 531-536. PMID 7824954 DOI: 10.1126/science.7824954  0.343
1995 Ge H, Zhao Y, Chait BT, Roeder RG. Phosphorylation negatively regulates the function of coactivator PC4. Proceedings of the National Academy of Sciences of the United States of America. 91: 12691-5. PMID 7809103 DOI: 10.1073/Pnas.91.26.12691  0.318
1995 Sinn E, Wang Z, Kovelman R, Roeder RG. Cloning and characterization of a TFIIIC2 subunit (TFIIICβ) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors Genes and Development. 9: 675-685. PMID 7729686 DOI: 10.1101/GAD.9.6.675  0.421
1995 DeJong J, Bernstein R, Roeder RG. Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription. Proceedings of the National Academy of Sciences of the United States of America. 92: 3313-7. PMID 7724559 DOI: 10.1073/PNAS.92.8.3313  0.452
1995 Nikolov DB, Chen H, Halay ED, Usheva AA, Hisatake K, Lee DK, Roeder RG, Burley SK. Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature. 377: 119-28. PMID 7675079 DOI: 10.1038/377119A0  0.355
1995 Ohkuma Y, Hashimoto S, Wang CK, Horikoshi M, Roeder RG. Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE-alpha. Molecular and Cellular Biology. 15: 4856-66. PMID 7651404 DOI: 10.1128/MCB.15.9.4856  0.36
1995 Wang Z, Roeder RG. Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains Proceedings of the National Academy of Sciences of the United States of America. 92: 7026-7030. PMID 7624363 DOI: 10.1073/pnas.92.15.7026  0.471
1994 Kretzschmar M, Meisterernst M, Roeder RG. Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 90: 11508-12. PMID 8265582 DOI: 10.1073/PNAS.90.24.11508  0.502
1994 Kokubo T, Gong DW, Yamashita S, Takada R, Roeder RG, Horikoshi M, Nakatani Y. Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit. Molecular and Cellular Biology. 13: 7859-63. PMID 8247000 DOI: 10.1128/mcb.13.12.7859-7863.1993  0.339
1994 Kretzschmar M, Stelzer G, Roeder RG, Meisterernst M. RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro. Molecular and Cellular Biology. 14: 3927-37. PMID 8196633 DOI: 10.1128/mcb.14.6.3927-3937.1994  0.485
1994 Tae Kook Kim, Roeder RG. Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation Proceedings of the National Academy of Sciences of the United States of America. 91: 4170-4174. PMID 8183887 DOI: 10.1073/PNAS.91.10.4170  0.359
1994 Kim TK, Hashimoto S, Kelleher RJ, Flanagan PM, Kornberg RD, Horikoshi M, Roeder RG. Effects of activation-defective TBP mutations on transcription initiation in yeast. Nature. 369: 252-5. PMID 8183347 DOI: 10.1038/369252a0  0.413
1994 Ohkuma Y, Roeder RG. Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation Nature. 368: 160-163. PMID 8166891 DOI: 10.1038/368160A0  0.389
1994 Lagna G, Kovelman R, Sukegawa J, Roeder RG. Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC. Molecular and Cellular Biology. 14: 3053-64. PMID 8164661 DOI: 10.1128/mcb.14.5.3053-3064.1994  0.773
1994 Yoon JB, Li G, Roeder RG. Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro. Molecular and Cellular Biology. 14: 1776-85. PMID 8114710 DOI: 10.1128/mcb.14.3.1776-1785.1994  0.38
1994 Ge H, Roeder RG. Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes Cell. 78: 513-523. PMID 8062391 DOI: 10.1016/0092-8674(94)90428-6  0.372
1994 Kokubo T, Gong DW, Wootton JC, Horikoshi M, Roeder RG, Nakatani Y. Molecular cloning of Drosophila TFIID subunits. Nature. 367: 484-7. PMID 7545910 DOI: 10.1038/367484A0  0.381
1994 Martinez E, Lagna G, Roeder RG. Overlapping transcription by RNA polymerases II and III of the Xenopus TFIIIA gene in somatic cells. Journal of Biological Chemistry. 269: 25692-25698. DOI: 10.1016/s0021-9258(18)47304-8  0.431
1994 Kim T, Roeder R. Involvement of the basic repeat domain of TATA-binding protein (TBP) in transcription by RNA polymerases I, II, and III. Journal of Biological Chemistry. 269: 4891-4894. DOI: 10.1016/s0021-9258(17)37628-7  0.374
1994 Qin X, Luo Y, Suh H, Wayne J, Misulovin Z, Roeder R, Nussenzweig M. Transformation by homeobox genes can be mediated by selective transcriptional repression. The Embo Journal. 13: 5967-5976. DOI: 10.1002/J.1460-2075.1994.Tb06942.X  0.393
1994 Martinez E, Chiang C, Ge H, Roeder R. TATA-binding protein-associated factor(s) in TFIID function through the initiator to direct basal transcription from a TATA-less class II promoter. The Embo Journal. 13: 3115-3126. DOI: 10.1002/j.1460-2075.1994.tb06610.x  0.34
1993 Hisatake K, Roeder RG, Horikoshi M. Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity. Nature. 363: 744-7. PMID 8515820 DOI: 10.1038/363744A0  0.362
1993 Hisatake K, Hasegawa S, Takada R, Nakatani Y, Horikoshi M, Roeder RG. The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature. 362: 179-81. PMID 8450888 DOI: 10.1038/362179A0  0.444
1993 Malik S, Lee DK, Roeder RG. Potential RNA polymerase II-induced interactions of transcription factor TFIIB. Molecular and Cellular Biology. 13: 6253-9. PMID 8413225 DOI: 10.1128/mcb.13.10.6253-6259.1993  0.448
1993 Fondell JD, Roy AL, Roeder RG. Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: Implications for active repression Genes and Development. 7: 1400-1410. PMID 8392477 DOI: 10.1101/Gad.7.7B.1400  0.415
1993 Roy AL, Carruthers C, Gutjahr T, Roeder RG. Direct role for Myc in transcription initiation mediated by interactions with TFII-I Nature. 365: 359-361. PMID 8377829 DOI: 10.1038/365359a0  0.38
1993 Roy AL, Malik S, Meisterernst M, Roeder RG. An alternative pathway for transcription initiation involving TFII-I Nature. 365: 355-359. PMID 8377828 DOI: 10.1038/365355a0  0.414
1993 Yamashita S, Hisatake K, Kokubo T, Doi K, Roeder RG, Horikoshi M, Nakatani Y. Transcription factor TFIIB sites important for interaction with promoter-bound TFIID. Science (New York, N.Y.). 261: 463-6. PMID 8332911 DOI: 10.1126/SCIENCE.8332911  0.438
1993 Yoganathan T, Horikoshi M, Roeder RG, Sells BH. Direct binding of yeast transcription factor (TFIID) to the ribosomal protein L32 (rpL32) TATA-less promoter sequence. Febs Letters. 326: 163-6. PMID 8325365 DOI: 10.1016/0014-5793(93)81783-V  0.386
1993 DeJong J, Roeder RG. A single cDNA, hTFIIA/α, encodes both the p35 and p19 subunits of human TFIIA Genes and Development. 7: 2220-2234. PMID 8224848 DOI: 10.1101/GAD.7.11.2220  0.306
1993 Chiang CM, Ge H, Wang Z, Hoffmann A, Roeder RG. Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. The Embo Journal. 12: 2749-62. PMID 7687540 DOI: 10.1002/J.1460-2075.1993.Tb05936.X  0.59
1992 Sumimoto H, Ohkuma Y, Sinn E, Kato H, Shimasaki S, Horikoshi M, Roeder RG. Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Nature. 354: 401-4. PMID 1956404 DOI: 10.1038/354401A0  0.313
1992 Chang LA, Smith T, Pognonec P, Roeder RG, Murialdo H. Identification of USF as the ubiquitous murine factor that binds to and stimulates transcription from the immunoglobulin lambda 2-chain promoter. Nucleic Acids Research. 20: 287-93. PMID 1741254 DOI: 10.1093/NAR/20.2.287  0.372
1992 Horikoshi M, Bertuccioli C, Takada R, Wang J, Yamamoto T, Roeder RG. Transcription factor TFIID induces DNA bending upon binding to the TATA element. Proceedings of the National Academy of Sciences of the United States of America. 89: 1060-4. PMID 1736286 DOI: 10.1073/PNAS.89.3.1060  0.371
1992 Kato H, Sumimoto H, Pognonec P, Chen CH, Rosen CA, Roeder RG. HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes & Development. 6: 655-66. PMID 1559613 DOI: 10.1101/GAD.6.4.655  0.385
1992 Murphy S, Yoon JB, Gerster T, Roeder RG. Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Molecular and Cellular Biology. 12: 3247-61. PMID 1535687 DOI: 10.1128/mcb.12.7.3247-3261.1992  0.451
1992 Yoganathan T, Horikoshi M, Hasegawa S, Roeder RG, Sells BH. Yeast transcription factor IID participates in cell-free transcription of a mammalian ribosomal protein TATA-less promoter. The Biochemical Journal. 285: 721-3. PMID 1497610  0.48
1992 Takada R, Nakatani Y, Hoffmann A, Kokubo T, Hasegawa S, Roeder RG, Horikoshi M. Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau). Proceedings of the National Academy of Sciences of the United States of America. 89: 11809-13. PMID 1465404 DOI: 10.1073/Pnas.89.24.11809  0.535
1992 Nikolov DB, Hu SH, Lin J, Gasch A, Hoffmann A, Horikoshi M, Chua NH, Roeder RG, Burley SK. Crystal structure of TFIID TATA-box binding protein. Nature. 360: 40-6. PMID 1436073 DOI: 10.1038/360040A0  0.463
1992 Luo Y, Fujii H, Gerster T, Roeder RG. A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell. 71: 231-41. PMID 1423591 DOI: 10.1016/0092-8674(92)90352-D  0.309
1992 Kirschbaum BJ, Pognonec P, Roeder RG. Definition of the transcriptional activation domain of recombinant 43-kilodalton USF. Molecular and Cellular Biology. 12: 5094-101. PMID 1406684 DOI: 10.1128/mcb.12.11.5094-5101.1992  0.365
1992 Pognonec P, Kato H, Roeder R. The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner. Journal of Biological Chemistry. 267: 24563-24567. DOI: 10.1016/s0021-9258(18)35801-0  0.358
1992 Kovelman R, Roeder R. Purification and characterization of two forms of human transcription factor IIIC. Journal of Biological Chemistry. 267: 24446-24456. DOI: 10.1016/s0021-9258(18)35787-9  0.317
1991 Ohkuma Y, Sumimoto H, Horikoshi M, Roeder RG. Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE. Proceedings of the National Academy of Sciences of the United States of America. 87: 9163-7. PMID 2251258 DOI: 10.1073/PNAS.87.23.9163  0.37
1991 Sumimoto H, Ohkuma Y, Yamamoto T, Horikoshi M, Roeder RG. Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG. Proceedings of the National Academy of Sciences of the United States of America. 87: 9158-62. PMID 2251257 DOI: 10.1073/PNAS.87.23.9158  0.474
1991 Meisterernst M, Horikoshi M, Roeder RG. Recombinant yeast TFIID, a general transcription factor, mediates activation by the gene-specific factor USF in a chromatin assembly assay. Proceedings of the National Academy of Sciences of the United States of America. 87: 9153-7. PMID 2251256 DOI: 10.1073/PNAS.87.23.9153  0.441
1991 Gregor PD, Sawadogo M, Roeder RG. The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes & Development. 4: 1730-40. PMID 2249772 DOI: 10.1101/GAD.4.10.1730  0.318
1991 Ponce E, Lloyd JA, Pierani A, Roeder RG, Lingrel JB. Transcription factor OTF-1 interacts with two distinct DNA elements in the A gamma-globin gene promoter. Biochemistry. 30: 2961-7. PMID 2007132 DOI: 10.1021/Bi00225A033  0.366
1991 Kaulen H, Pognonec P, Gregor PD, Roeder RG. The Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression. Molecular and Cellular Biology. 11: 412-24. PMID 1986236 DOI: 10.1128/mcb.11.1.412-424.1991  0.369
1991 Roy AL, Meisterernst M, Pognonec P, Roeder RG. Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF Nature. 354: 245-248. PMID 1961251 DOI: 10.1038/354245a0  0.39
1991 Hoffmann A, Roeder RG. Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Research. 19: 6337-8. PMID 1956801 DOI: 10.1093/Nar/19.22.6337  0.366
1991 Ohkuma Y, Sumimoto H, Hoffmann A, Shimasaki S, Horikoshi M, Roeder RG. Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. Nature. 354: 398-401. PMID 1956403 DOI: 10.1038/354398A0  0.571
1991 Malik S, Hisatake K, Sumimoto H, Horikoshi M, Roeder RG. Sequence of general transcription factor TFIIB and relationships to other initiation factors. Proceedings of the National Academy of Sciences of the United States of America. 88: 9553-7. PMID 1946368 DOI: 10.1073/PNAS.88.21.9553  0.422
1991 Meisterernst M, Roeder RG. Family of proteins that interact with TFIID and regulate promoter activity Cell. 67: 557-567. PMID 1934060 DOI: 10.1016/0092-8674(91)90530-C  0.414
1991 Pognonec P, Roeder RG. Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF Molecular and Cellular Biology. 11: 5125-5136. PMID 1922036 DOI: 10.1128/mcb.11.10.5125-5136.1991  0.406
1991 Poon D, Schroeder S, Wang CK, Yamamoto T, Horikoshi M, Roeder RG, Weil PA. The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth. Molecular and Cellular Biology. 11: 4809-21. PMID 1922021 DOI: 10.1128/mcb.11.10.4809-4821.1991  0.306
1991 Meisterernst M, Roy AL, Lieu HM, Roeder RG. Activation of class II gene transcription by regulatory factors is potentiated by a novel activity Cell. 66: 981-993. PMID 1889091 DOI: 10.1016/0092-8674(91)90443-3  0.387
1991 Tamura T, Sumita K, Fujino I, Aoyama A, Horikoshi M, Hoffmann A, Roeder RG, Muramatsu M, Mikoshiba K. Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID). Nucleic Acids Research. 19: 3861-5. PMID 1861978 DOI: 10.1093/Nar/19.14.3861  0.449
1991 Workman JL, Taylor IC, Kingston RE, Roeder RG. Control of class II gene transcription during in vitro nucleosome assembly. Methods in Cell Biology. 35: 419-47. PMID 1779863 DOI: 10.1016/S0091-679X(08)60582-8  0.75
1991 Roeder RG. The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly Trends in Biochemical Sciences. 16: 402-408. PMID 1776168 DOI: 10.1016/0968-0004(91)90164-Q  0.424
1990 Hoffman A, Sinn E, Yamamoto T, Wang J, Roy A, Horikoshi M, Roeder RG. Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature. 346: 387-90. PMID 2374612 DOI: 10.1038/346387A0  0.365
1990 Workman JL, Roeder RG, Kingston RE. An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. The Embo Journal. 9: 1299-308. PMID 2323340 DOI: 10.1002/J.1460-2075.1990.Tb08239.X  0.729
1990 Katagiri F, Yamazaki K, Horikoshi M, Roeder RG, Chua NH. A plant DNA-binding protein increases the number of active preinitiation complexes in a human in vitro transcription system. Genes & Development. 4: 1899-909. PMID 2276624 DOI: 10.1101/Gad.4.11.1899  0.396
1990 Nakatani Y, Horikoshi M, Brenner M, Yamamoto T, Besnard F, Roeder RG, Freese E. A downstream initiation element required for efficient TATA box binding and in vitro function of TFIID. Nature. 348: 86-8. PMID 2234067 DOI: 10.1038/348086a0  0.394
1990 Hoffmann A, Horikoshi M, Wang CK, Schroeder S, Weil PA, Roeder RG. Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID. Genes & Development. 4: 1141-8. PMID 2210373 DOI: 10.1101/Gad.4.7.1141  0.514
1990 Gasch A, Hoffmann A, Horikoshi M, Roeder RG, Chua NH. Arabidopsis thaliana contains two genes for TFIID. Nature. 346: 390-4. PMID 2197561 DOI: 10.1038/346390A0  0.659
1990 Horikoshi M, Yamamoto T, Ohkuma Y, Weil PA, Roeder RG. Analysis of structure-function relationships of yeast TATA box binding factor TFIID. Cell. 61: 1171-8. PMID 2194665 DOI: 10.1016/0092-8674(90)90681-4  0.312
1990 Muhich ML, Iida CT, Horikoshi M, Roeder RG, Parker CS. cDNA clone encoding Drosophila transcription factor TFIID. Proceedings of the National Academy of Sciences of the United States of America. 87: 9148-52. PMID 2123550 DOI: 10.1073/Pnas.87.23.9148  0.69
1990 Pierani A, Heguy A, Fujii H, Roeder RG. Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters. Molecular and Cellular Biology. 10: 6204-15. PMID 2123291 DOI: 10.1128/mcb.10.12.6204-6215.1990  0.442
1990 Abate C, Luk D, Gagne E, Roeder RG, Curran T. Fos and jun cooperate in transcriptional regulation via heterologous activation domains. Molecular and Cellular Biology. 10: 5532-5. PMID 2119000 DOI: 10.1128/mcb.10.10.5532-5535.1990  0.382
1990 Yoza BK, Roeder RG. Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2 Molecular and Cellular Biology. 10: 2145-2153. PMID 2109187 DOI: 10.1128/mcb.10.5.2145-2153.1990  0.369
1990 Ohkuma Y, Horikoshi M, Roeder RG, Desplan C. Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins. Cell. 61: 475-84. PMID 1970761 DOI: 10.1016/0092-8674(90)90529-N  0.404
1990 Ohkuma Y, Horikoshi M, Roeder RG, Desplan C. Engrailed, a homeodomain protein, can repress in vitro transcription by competition with the TATA box-binding protein transcription factor IID. Proceedings of the National Academy of Sciences of the United States of America. 87: 2289-93. PMID 1969159 DOI: 10.1073/Pnas.87.6.2289  0.4
1990 Kovelman R, Roeder RG. Sarkosyl defines three intermediate steps in transcription initiation by RNA polymerase III: application to stimulation of transcription by E1A Genes and Development. 4: 646-658. PMID 1694510 DOI: 10.1101/GAD.4.4.646  0.458
1990 Gerster T, Balmaceda C, Roeder R. The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. The Embo Journal. 9: 1635-1643. DOI: 10.1002/j.1460-2075.1990.tb08283.x  0.378
1989 Scheidereit C, Cromlish JA, Gerster T, Kawakami K, Balmaceda CG, Currie RA, Roeder RG. A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature. 336: 551-7. PMID 2904654 DOI: 10.1038/336551A0  0.322
1989 Tan TH, Horikoshi M, Roeder RG. Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat. Molecular and Cellular Biology. 9: 1733-45. PMID 2786141 DOI: 10.1128/mcb.9.4.1733-1745.1989  0.301
1989 Scotto KW, Kaulen H, Roeder RG. Positive and negative regulation of the gene for transcription factor IIIA in Xenopus laevis oocytes Genes &Amp; Development. 3: 651-662. PMID 2744458  0.399
1989 Horikoshi M, Wang CK, Fujii H, Cromlish JA, Weil PA, Roeder RG. Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity. Proceedings of the National Academy of Sciences of the United States of America. 86: 4843-7. PMID 2662184 DOI: 10.1073/PNAS.86.13.4843  0.396
1989 Cromlish WA, Abmayr SM, Workman JL, Horikoshi M, Roeder RG. Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters. Journal of Virology. 63: 1869-76. PMID 2539489  0.516
1989 Murphy S, Pierani A, Scheidereit C, Melli M, Roeder RG. Purified octamer binding transcription factors stimulate RNA polymerase III--mediated transcription of the 7SK RNA gene. Cell. 59: 1071-80. PMID 2532066 DOI: 10.1016/0092-8674(89)90763-0  0.49
1989 Van Dyke MW, Sawadogo M, Roeder RG. Stability of transcription complexes on class II genes Molecular and Cellular Biology. 9: 342-344. PMID 2494433 DOI: 10.1128/mcb.9.1.342-344.1989  0.369
1989 Tan TH, Jia R, Roeder RG. Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax Journal of Virology. 63: 3761-3768. PMID 2474673 DOI: 10.1128/JVI.63.9.3761-3768.1989  0.314
1988 Hai TW, Horikoshi M, Roeder RG, Green MR. Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex. Cell. 54: 1043-51. PMID 3416355 DOI: 10.1016/0092-8674(88)90119-5  0.585
1988 Horikoshi M, Hai T, Lin YS, Green MR, Roeder RG. Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell. 54: 1033-42. PMID 3416354 DOI: 10.1016/0092-8674(88)90118-3  0.558
1988 Van Dyke MW, Roeder RG, Sawadogo M. Physical analysis of transcription preinitiation complex assembly on a class II gene promoter Science. 241: 1335-1338. PMID 3413495 DOI: 10.1126/Science.3413495  0.585
1988 O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485 DOI: 10.1126/Science.3413485  0.563
1988 Nakajima N, Horikoshi M, Roeder RG. Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Molecular and Cellular Biology. 8: 4028-40. PMID 3185540 DOI: 10.1128/mcb.8.10.4028-4040.1988  0.415
1988 LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460 DOI: 10.1101/Gad.2.1.32  0.76
1988 Scheidereit C, Heguy A, Roeder RG. Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro. Cell. 51: 783-93. PMID 3119226 DOI: 10.1016/0092-8674(87)90101-2  0.322
1988 Huang DH, Roeder RG. Delineation of DNA sequences that are important for in vitro transcription from the adenovirus EIIa late promoter Molecular and Cellular Biology. 8: 1906-1914. PMID 2968498 DOI: 10.1128/mcb.8.5.1906-1914.1988  0.302
1988 Hoeffler WK, Kovelman R, Roeder RG. Activation of transcription factor IIIC by the adenovirus E1A protein. Cell. 53: 907-20. PMID 2968157 DOI: 10.1016/S0092-8674(88)90409-6  0.488
1988 Workman JL, Abmayr SM, Cromlish WA, Roeder RG. Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly. Cell. 55: 211-9. PMID 2844412 DOI: 10.1016/0092-8674(88)90044-X  0.617
1988 Gerster T, Roeder RG. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins Proceedings of the National Academy of Sciences of the United States of America. 85: 6347-6351. PMID 2842768 DOI: 10.1073/PNAS.85.17.6347  0.395
1988 Ruben S, Poteat H, Tan T, Kawakami K, Roeder R, Haseltine W, Rosen CA. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product Science. 241: 89-92. PMID 2838905 DOI: 10.1126/Science.2838905  0.477
1988 Abmayr SM, Workman JL, Roeder RG. The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes & Development. 2: 542-53. PMID 2838379  0.609
1988 Sawadogo M, Van Dyke MW, Gregor PD, Roeder RG. Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. Journal of Biological Chemistry. 263: 11985-11993. DOI: 10.1016/s0021-9258(18)37883-9  0.395
1987 Pieler T, Hamm J, Roeder RG. The 5S gene internal control region is composed of three distinct sequence elements, organized as two functional domains with variable spacing. Cell. 48: 91-100. PMID 3791417 DOI: 10.1016/0092-8674(87)90359-X  0.405
1987 Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0  0.627
1987 Workman JL, Roeder RG. Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II. Cell. 51: 613-22. PMID 3677170 DOI: 10.1016/0092-8674(87)90130-9  0.64
1987 van Dyke MW, Roeder RG. Two forms of transcription factor TFIIIC in extracts from hela cells Nucleic Acids Research. 15: 5031-5039. PMID 3601665 DOI: 10.1093/nar/15.13.5031  0.413
1987 van Dyke MW, Roeder RG. Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes Nucleic Acids Research. 15: 4365-4374. PMID 3588299 DOI: 10.1093/nar/15.11.4365  0.492
1987 Van Dyke MW, Roeder RG. Multiple proteins bind to VA RNA genes of adenovirus Type 2 Molecular and Cellular Biology. 7: 1021-1031. PMID 3561405 DOI: 10.1128/mcb.7.3.1021-1031.1987  0.313
1987 Reinberg D, Horikoshi M, Roeder R. Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site. Journal of Biological Chemistry. 262: 3322-3330. DOI: 10.1016/s0021-9258(18)61506-6  0.332
1987 Reinberg D, Roeder R. Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. Journal of Biological Chemistry. 262: 3310-3321. DOI: 10.1016/s0021-9258(18)61505-4  0.389
1987 Hawley D, Roeder R. Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. Journal of Biological Chemistry. 262: 3452-3461. DOI: 10.1016/s0021-9258(18)61372-9  0.327
1986 Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962 DOI: 10.1073/Pnas.83.19.7241  0.571
1986 Sive HL, Roeder RG. Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes Proceedings of the National Academy of Sciences of the United States of America. 83: 6382-6386. PMID 3462701  0.697
1986 Mizushima-Sugano J, Roeder RG. Cell-type-specific transcription of an immunoglobulin κ light chain gene in vitro Proceedings of the National Academy of Sciences of the United States of America. 83: 8511-8515. PMID 3095838 DOI: 10.1073/PNAS.83.22.8511  0.38
1986 Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588 DOI: 10.1128/mcb.6.10.3329-3340.1986  0.729
1986 Perry M, Thomsen GH, Roeder RG. Major transitions in histone gene expression do not occur during development in Xenopus laevis. Developmental Biology. 116: 532-8. PMID 3015703 DOI: 10.1016/0012-1606(86)90154-5  0.713
1986 Lebovitz RM, Roeder RG. Parvovirus H-1 expression: mapping of the abundant cytoplasmic transcripts and identification of promoter sites and overlapping transcription units. Journal of Virology. 58: 271-80. PMID 3009844 DOI: 10.1128/JVI.58.2.271-280.1986  0.35
1986 Abmayr SM, Feldman LD, Roeder RG. In vitro stimulation of specific RNA polymerase II-mediated transcription by the pseudorabies virus immediate early protein. Cell. 43: 821-9. PMID 3000617 DOI: 10.1016/0092-8674(85)90255-7  0.355
1986 Bieker JJ, Roeder RG. Characterization of the nucleotide requirement for elimination of the rate-limiting step in 5 S RNA gene transcription. Journal of Biological Chemistry. 261: 9732-9738. DOI: 10.1016/s0021-9258(18)67576-3  0.382
1985 Sawadogo M, Roeder RG. Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region Cell. 43: 165-175. PMID 4075392 DOI: 10.1016/0092-8674(85)90021-2  0.427
1985 Hoeffler WK, Roeder RG. Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus Cell. 41: 955-963. PMID 4005953 DOI: 10.1016/S0092-8674(85)80076-3  0.397
1985 Bieker JJ, Martin PL, Roeder RG. Formation of a rate-limiting intermediate in 5S RNA gene transcription Cell. 40: 119-127. PMID 3967290 DOI: 10.1016/0092-8674(85)90315-0  0.471
1985 Sawadogo M, Roeder RG. Factors involved in specific transcription by human RNA polymerase II: Analysis by a rapid and quantitative in vitro assay Proceedings of the National Academy of Sciences of the United States of America. 82: 4394-4398. PMID 3925456 DOI: 10.1073/PNAS.82.13.4394  0.395
1985 Perry M, Thomsen GH, Roeder RG. Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements. Journal of Molecular Biology. 185: 479-99. PMID 3863963 DOI: 10.1016/0022-2836(85)90065-8  0.685
1985 Lassar AB, Hamer DH, Roeder RG. Stable transcription complex on a class III gene in a minichromosome. Molecular and Cellular Biology. 5: 40-5. PMID 2984553 DOI: 10.1128/mcb.5.1.40-45.1985  0.737
1985 Hawley DK, Roeder RG. Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. Journal of Biological Chemistry. 260: 8163-8172. DOI: 10.1016/s0021-9258(17)39577-7  0.379
1984 Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823  0.615
1984 Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888 DOI: 10.1128/mcb.4.12.2723-2734.1984  0.725
1984 Ginsberg AM, King BO, Roeder RG. Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell. 39: 479-89. PMID 6210149 DOI: 10.1016/0092-8674(84)90455-0  0.396
1984 Sawadogo M, Roeder RG. Energy requirement for specific transcription initiation by the human RNA polymerase II system. Journal of Biological Chemistry. 259: 5321-5326. DOI: 10.1016/s0021-9258(17)42993-0  0.358
1984 Emerson BM, Roeder RG. DNA sequences and transcription factor interactions of active and inactive forms of mammalian 5 S RNA genes. Journal of Biological Chemistry. 259: 7926-7935. DOI: 10.1016/s0021-9258(17)42881-x  0.414
1984 Emerson BM, Roeder RG. Isolation and genomic arrangement of active and inactive forms of mammalian 5 S RNA genes. Journal of Biological Chemistry. 259: 7916-7925. DOI: 10.1016/s0021-9258(17)42880-8  0.302
1983 Dignam JD, Martin PL, Shastry BS, Roeder RG. Eukaryotic gene transcription with purified components. Methods in Enzymology. 101: 582-98. PMID 6888276 DOI: 10.1016/0076-6879(83)01039-3  0.394
1983 Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Research. 11: 1475-89. PMID 6828386 DOI: 10.1093/nar/11.5.1475  0.359
1983 Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409  0.573
1983 Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359 DOI: 10.1073/PNAS.80.15.4770  0.436
1983 Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835 DOI: 10.1128/mcb.3.4.539-550.1983  0.694
1983 Lassar AB, Martin PL, Roeder RG. Transcription of class III genes: formation of preinitiation complexes. Science (New York, N.Y.). 222: 740-8. PMID 6356356  0.735
1982 Lee DC, Roeder RG, Wold WSM. DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2 Proceedings of the National Academy of Sciences of the United States of America. 79: 41-45. PMID 6275389 DOI: 10.1073/PNAS.79.1.41  0.321
1982 Shastry BS, Ng SY, Roeder RG. Multiple factors involved in the transcription of class III genes in Xenopus laevis. Journal of Biological Chemistry. 257: 12979-12986. DOI: 10.1016/s0021-9258(18)33611-1  0.393
1981 Lee DC, Roeder RG. Transcription of adenovirus type 2 genes in a cell-free system: Apparent heterogeneity of initiation at some promoters Molecular and Cellular Biology. 1: 635-651. PMID 9279377 DOI: 10.1128/mcb.1.7.635-651.1981  0.421
1981 Sakonju S, Brown DD, Engelke D, Ng SY, Shastry BS, Roeder RG. The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell. 23: 665-9. PMID 7226225 DOI: 10.1016/0092-8674(81)90429-3  0.762
1981 Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1  0.547
1981 Green MR, Straus SE, Roeder RG. Transcripts of the adenovirus-associated virus genome: multiple polyadenylated RNAs including a potential primary transcript. Journal of Virology. 35: 560-5. PMID 6255194 DOI: 10.1128/JVI.35.2.560-565.1980  0.342
1981 Roeder RG, Heintz N, Honda B, Lee D, Luse D, Matsui T, Segall J, Shastry B. Initiation of Eukaryotic Gene Transcription in Vitro Biochemical Society Transactions. 9: 120P-120P. DOI: 10.1042/bst009120p  0.621
1980 Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7  0.522
1980 Luse DS, Roeder RG. Accurate transcription initiation on a purified mouse β-globin DNA fragment in a cell-free system Cell. 20: 691-699. PMID 7418005 DOI: 10.1016/0092-8674(80)90315-3  0.353
1980 Green MR, Roeder RG. Definition of a novel promoter for the major adenovirus-associated virus mRNA Cell. 22: 231-242. PMID 6253077 DOI: 10.1016/0092-8674(80)90171-3  0.364
1980 Honda BM, Roeder RG. Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation Cell. 22: 119-126. PMID 6159099 DOI: 10.1016/0092-8674(80)90160-9  0.416
1980 Engelke DR, Ng SY, Shastry BS, Roeder RG. Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes Cell. 19: 717-728. PMID 6153931 DOI: 10.1016/S0092-8674(80)80048-1  0.701
1980 Weil PA, Luse DS, Segall J, Roeder RG. Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell. 18: 469-84. PMID 498279 DOI: 10.1016/0092-8674(79)90065-5  0.431
1980 Matsui T, Segall J, Weil P, Roeder R. Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. Journal of Biological Chemistry. 255: 11992-11996. DOI: 10.1016/s0021-9258(19)70232-4  0.394
1980 Segall J, Matsui T, Roeder R. Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. Journal of Biological Chemistry. 255: 11986-11991. DOI: 10.1016/s0021-9258(19)70231-2  0.447
1979 Bitter GA, Roeder RG. Transcription of viral genes in chromatin from adenovirus 2 transformed cells by exogenous eukaryotic RNA polymerases Nucleic Acids Research. 7: 433-452. PMID 493152 DOI: 10.1093/nar/7.2.433  0.404
1979 Ng SY, Parker CS, Roeder RG. Transcription of cloned Xenopus 5S RNA genes by X. laevis RNA polymerase III in reconstituted systems. Proceedings of the National Academy of Sciences of the United States of America. 76: 136-40. PMID 284325  0.691
1979 Green MR, Lebovitz RM, Roeder RG. Expression of the autonomous parvovirus H1 genome: evidence for a single transcriptional unit and multiple spliced polyadenylated transcripts. Cell. 17: 967-77. PMID 226267 DOI: 10.1016/0092-8674(79)90336-2  0.393
1979 Weil PA, Segall J, Harris B, Ng SY, Roeder RG. Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. Journal of Biological Chemistry. 254: 6163-6173. DOI: 10.1016/s0021-9258(18)50533-0  0.401
1978 Bitter GA, Roeder RG. Transcription of viral genes by RNA polymerase II in nuclei isolated from adenovirus 2 transformed cells Biochemistry. 17: 2198-2205. PMID 667018 DOI: 10.1021/BI00604A028  0.384
1978 Hagopian HK, Ingram VM, Roeder RG, Jaehning JA, Sklar VEF. Transcription of chromatin in isolated nuclei by exogenous RNA polymerases Cell. 13: 213-214. PMID 342114 DOI: 10.1016/0092-8674(78)90189-7  0.721
1978 Parker CS, Jaehning JA, Roeder RG. Faithful gene transcription by eukaryotic RNA polymerases in reconstructed systems. Cold Spring Harbor Symposia On Quantitative Biology. 42: 577-87. PMID 277365  0.803
1977 Sklar VEF, Roeder RG. Transcription of specific genes in isolated nuclei by exogenous RNA polymerases Cell. 10: 405-414. PMID 844100 DOI: 10.1016/0092-8674(77)90028-9  0.321
1977 Parker CS, Roeder RG. Selective and accurate transcription of the Xenopus laevis 5S RNA genes in isolated chromatin by purified RNA polymerase III. Proceedings of the National Academy of Sciences of the United States of America. 74: 44-8. PMID 264693 DOI: 10.1073/Pnas.74.1.44  0.693
1977 Jaehning J, Roeder R. Transcription of specific adenovirus genes in isolated nuclei by exogenous RNA polymerases Journal of Biological Chemistry. 252: 8753-8761. DOI: 10.1016/s0021-9258(19)75286-7  0.415
1976 Weinmann R, Jaehning JA, Raskas HJ, Roeder RG. Viral RNA synthesis and levels of DNA dependent RNA polymerases during replication of adenovirus 2 Journal of Virology. 17: 114-126. PMID 1206798 DOI: 10.1128/Jvi.17.1.114-126.1976  0.79
1975 Weinmann R, Raskas HJ, Roeder RG. Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection. Proceedings of the National Academy of Sciences of the United States of America. 71: 3426-39. PMID 4530313 DOI: 10.1073/Pnas.71.9.3426  0.707
1975 Jaehning JA, Stewart CC, Roeder RG. DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin Cell. 4: 51-57. PMID 1116173 DOI: 10.1016/0092-8674(75)90133-6  0.693
1975 Weinmann R, Raskas HJ, Roeder RG. The transcriptional role of host DNA-dependent RNA polymerases in adenovirus-infected KB cells. Cold Spring Harbor Symposia On Quantitative Biology. 495-9. PMID 1057477 DOI: 10.1101/SQB.1974.039.01.061  0.336
1974 Weinmann R, Roeder RG. Role of DNA dependent RNA polymerase III in the transcription of the tRNA and 5S RNA genes Proceedings of the National Academy of Sciences of the United States of America. 71: 1790-1794. PMID 4525293 DOI: 10.1073/Pnas.71.5.1790  0.701
1974 Schwartz LB, Lawrence C, Thach RE, Roeder RG. Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on host RNA synthesis and RNA polymerases. Journal of Virology. 14: 611-9. PMID 4368675 DOI: 10.1128/JVI.14.3.611-619.1974  0.309
1972 Reeder RH, Roeder RG. Ribosomal RNA synthesis in isolated nuclei. Journal of Molecular Biology. 67: 433-41. PMID 4558099 DOI: 10.1016/0022-2836(72)90461-5  0.624
1970 Roeder RG, Rutter WJ. Multiple ribonucleic acid polymerases and ribonucleic acid synthesis during sea urchin development. Biochemistry. 9: 2543-53. PMID 5423271 DOI: 10.1021/Bi00814A023  0.402
1970 Roeder RG, Rutter WJ. Specific nucleolar and nucleoplasmic RNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 65: 675-82. PMID 5267147 DOI: 10.1073/Pnas.65.3.675  0.58
1970 Lindell TJ, Weinberg F, Morris PW, Roeder RG, Rutter WJ. Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (New York, N.Y.). 170: 447-9. PMID 4918258 DOI: 10.1126/science.170.3956.447  0.552
1970 Roeder RG, Reeder RH, Brown DD. Multiple Forms of RNA Polymerase in Xenopus laevis: Their Relationship to RNA Synthesis in vivo and Their Fidelity of Transcription in vitro Cold Spring Harbor Symposia On Quantitative Biology. 35: 727-735. DOI: 10.1101/Sqb.1970.035.01.088  0.708
1969 Roeder RG, Rutter WJ. Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature. 224: 234-7. PMID 5344598 DOI: 10.1038/224234a0  0.546
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