Chia-Chen Liu, Ph.D. - Publications

2010 Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Cell Biology, Molecular Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yamazaki Y, Zhao N, Caulfield TR, Liu CC, Bu G. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies. Nature Reviews. Neurology. PMID 31367008 DOI: 10.1038/s41582-019-0228-7  0.52
2019 Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Liu CC, et al. Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 2923. PMID 31266955 DOI: 10.1038/s41467-019-10950-2  0.52
2019 Shinohara M, Shinohara M, Zhao J, Fu Y, Liu CC, Kanekiyo T, Bu G. 5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway. International Journal of Molecular Sciences. 20. PMID 30934555 DOI: 10.3390/ijms20061488  0.52
2019 Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, ... ... Liu CC, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nature Communications. 10: 1365. PMID 30911003 DOI: 10.1038/s41467-019-09118-9  0.52
2019 Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1. The Journal of Clinical Investigation. PMID 30741718 DOI: 10.1172/JCI124853  0.52
2018 Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, et al. APOE ε2 is associated with increased tau pathology in primary tauopathy. Nature Communications. 9: 4388. PMID 30348994 DOI: 10.1038/s41467-018-06783-0  0.52
2017 Liu CC, Zhao N, Fu Y, Wang N, Linares C, Tsai CW, Bu G. ApoE4 Accelerates Early Seeding of Amyloid Pathology. Neuron. 96: 1024-1032.e3. PMID 29216449 DOI: 10.1016/j.neuron.2017.11.013  0.52
2017 Tachibana M, Yamazaki Y, Liu CC, Bu G, Kanekiyo T. Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice. Experimental Neurology. 300: 13-21. PMID 29106980 DOI: 10.1016/j.expneurol.2017.10.023  0.52
2017 Kang SS, Kurti A, Baker KE, Liu CC, Colonna M, Ulrich JD, Holtzman DM, Bu G, Fryer JD. Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal. Human Molecular Genetics. PMID 29040522 DOI: 10.1093/hmg/ddx366  0.52
2017 Zhao N, Liu CC, Van Ingelgom AJ, Martens YA, Linares C, Knight JA, Painter MM, Sullivan PM, Bu G. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes. Neuron. 96: 115-129.e5. PMID 28957663 DOI: 10.1016/j.neuron.2017.09.003  0.52
2017 Wojtas AM, Kang SS, Olley BM, Gatherer M, Shinohara M, Lozano PA, Liu CC, Kurti A, Baker KE, Dickson DW, Yue M, Petrucelli L, Bu G, Carare RO, Fryer JD. Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 28701379 DOI: 10.1073/pnas.1701137114  0.52
2017 Zhao N, Liu CC, Qiao W, Bu G. Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease. Biological Psychiatry. PMID 28434655 DOI: 10.1016/j.biopsych.2017.03.003  0.52
2017 Liu CC, Hu J, Zhao N, Wang J, Na W, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28275161 DOI: 10.1523/JNEUROSCI.3442-16.2017  0.52
2017 Rogers JT, Liu CC, Zhao N, Wang J, Putzke T, Yang L, Shinohara M, Fryer JD, Kanekiyo T, Bu G. Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice. Neurobiology of Aging. 53: 112-121. PMID 28254590 DOI: 10.1016/j.neurobiolaging.2017.02.001  0.52
2017 Zhong L, Chen XF, Wang T, Wang Z, Liao C, Wang Z, Huang R, Wang D, Li X, Wu L, Jia L, Zheng H, Painter M, Atagi Y, Liu CC, et al. Soluble TREM2 induces inflammatory responses and enhances microglial survival. The Journal of Experimental Medicine. PMID 28209725 DOI: 10.1084/jem.20160844  0.52
2017 Zheng H, Jia L, Liu CC, Li Zhong ZR, Yang L, Chen XF, Fryer JD, Wang X, Zhang YW, Xu H, Bu G. TREM2 promotes microglial survival by activating Wnt/β-catenin pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28077724 DOI: 10.1523/JNEUROSCI.2459-16.2017  0.52
2016 Yang L, Liu CC, Zheng H, Kanekiyo T, Atagi Y, Jia L, Wang D, N'songo A, Can D, Xu H, Chen XF, Bu G. LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways. Journal of Neuroinflammation. 13: 304. PMID 27931217 DOI: 10.1186/s12974-016-0772-7  0.52
2016 Kang SS, Kurti A, Wojtas A, Baker KE, Liu CC, Kanekiyo T, Deming Y, Cruchaga C, Estus S, Bu G, Fryer JD. Identification of Plexin A4 as a novel Clusterin receptor links two Alzheimer's disease risk genes. Human Molecular Genetics. PMID 27378688 DOI: 10.1093/hmg/ddw188  0.52
2016 Qi M, Dang Y, Xu Q, Yu L, Liu C, Yuan Y, Wang J. Microcystin-LR induced developmental toxicity and apoptosis in zebrafish (Danio rerio) larvae by activation of ER stress response. Chemosphere. 157: 166-173. PMID 27219292 DOI: 10.1016/j.chemosphere.2016.05.038  0.32
2016 Liu R, Wang S, Fang S, Wang J, Chen J, Huang X, He X, Liu C. Liquid Crystalline Nanoparticles as an Ophthalmic Delivery System for Tetrandrine: Development, Characterization, and In Vitro and In Vivo Evaluation. Nanoscale Research Letters. 11: 254. PMID 27188974 DOI: 10.1186/s11671-016-1471-0  0.32
2016 Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, et al. Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease. Acta Neuropathologica. PMID 27179972 DOI: 10.1007/s00401-016-1580-y  0.52
2016 Liu C, Wang J, Zhan B, Cheng G. Neuronal activity and the expression of hypothalamic oxytocin and vasopressin in social versus cocaine conditioning. Behavioural Brain Research. PMID 27163750 DOI: 10.1016/j.bbr.2016.05.010  0.32
2016 Ding S, Zhang J, Tian Y, Huang B, Yuan Y, Liu C. Magnesium modification up-regulates the bioactivity of bone morphogenetic protein-2 upon calcium phosphate cement via enhanced BMP receptor recognition and Smad signaling pathway. Colloids and Surfaces. B, Biointerfaces. 145: 140-151. PMID 27156155 DOI: 10.1016/j.colsurfb.2016.04.045  0.32
2016 Fu Y, Zhao J, Atagi Y, Nielsen HM, Liu CC, Zheng H, Shinohara M, Kanekiyo T, Bu G. Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan. Molecular Neurodegeneration. 11: 37. PMID 27151330 DOI: 10.1186/s13024-016-0099-y  0.52
2016 Zheng H, Liu CC, Atagi Y, Chen XF, Jia L, Yang L, He W, Zhang X, Kang SS, Rosenberry TL, Fryer JD, Zhang YW, Xu H, Bu G. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation. Neurobiology of Aging. 42: 132-41. PMID 27143430 DOI: 10.1016/j.neurobiolaging.2016.03.004  0.52
2016 Zhang X, Hu J, Zhong L, Wang N, Yang L, Liu CC, Li H, Wang X, Zhou Y, Zhang Y, Xu H, Bu G, Zhuang J. Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice. Neuropharmacology. PMID 27114256 DOI: 10.1016/j.neuropharm.2016.04.032  0.52
2016 Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, et al. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3848-59. PMID 27030769 DOI: 10.1523/JNEUROSCI.3757-15.2016  0.52
2016 Liu CC, Zhao N, Yamaguchi Y, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G. Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease. Science Translational Medicine. 8: 332ra44. PMID 27030596 DOI: 10.1126/scitranslmed.aad3650  0.52
2016 Yamazaki Y, Baker DJ, Tachibana M, Liu CC, van Deursen JM, Brott TG, Bu G, Kanekiyo T. Vascular Cell Senescence Contributes to Blood-Brain Barrier Breakdown. Stroke; a Journal of Cerebral Circulation. PMID 26883501 DOI: 10.1161/STROKEAHA.115.010835  0.52
2016 Li Y, Liu C, Zhao M, Li R, Xiao H, Wang K, Zhang J. Multi-Topic Tracking Model for dynamic social network Physica a: Statistical Mechanics and Its Applications. 454: 51-56. DOI: 10.1016/j.physa.2016.02.038  0.32
2016 Liu C, Hong J, Zhang Y, Zhao Y, Wang L, Wei L, Chen S, Wang G, Li J. Synthesis of γ-Al2O3 nanofibers stabilized Co3O4 nanoparticles as highly active and stable Fischer-Tropsch synthesis catalysts Fuel. 180: 777-784. DOI: 10.1016/j.fuel.2016.04.006  0.36
2016 Li F, Zuo S, Yu P, Zhou B, Wang L, Liu C, Wei H, Xu H. Distribution and expression of the enterotoxin genes of Bacillus cereus in food products from Jiangxi Province, China Food Control. 67: 155-162. DOI: 10.1016/j.foodcont.2016.02.049  0.52
2016 Wang P, Deng S, He Y, Liu C, Zhang J. Oxidation and hot corrosion behavior of Al2O3/YSZ coatings prepared by cathode plasma electrolytic deposition Corrosion Science. DOI: 10.1016/j.corsci.2016.03.017  0.32
2016 Bartoli B, Bernardini P, Bi XJ, Cao Z, Catalanotti S, Chen SZ, Chen TL, Cui SW, Dai BZ, D'Amone A, Danzengluobu, De Mitri I, D'Ettorre Piazzoli B, Di Girolamo T, Di Sciascio G, ... ... Liu C, et al. Detection of thermal neutrons with the PRISMA-YBJ array in extensive air showers selected by the ARGO-YBJ experiment Astroparticle Physics. 81: 49-60. DOI: 10.1016/j.astropartphys.2016.04.007  0.32
2015 Tachibana M, Shinohara M, Yamazaki Y, Liu CC, Rogers J, Bu G, Kanekiyo T. Rescuing Effects of RXR Agonist Bexarotene on Aging-related Synapse Loss Depend on Neuronal LRP1. Experimental Neurology. PMID 26688581 DOI: 10.1016/j.expneurol.2015.12.003  0.52
2015 Atagi Y, Liu CC, Painter MM, Chen XF, Verbeeck C, Zheng H, Li X, Rademakers R, Kang SS, Xu H, Younkin S, Das P, Fryer JD, Bu G. Apolipoprotein E is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2). The Journal of Biological Chemistry. PMID 26374899 DOI: 10.1074/jbc.M115.679043  0.52
2015 Wren MC, Zhao J, Liu CC, Murray ME, Atagi Y, Davis MD, Fu Y, Okano HJ, Ogaki K, Strongosky AJ, Tacik P, Rademakers R, Ross OA, Dickson DW, Wszolek ZK, et al. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells. Molecular Neurodegeneration. 10: 46. PMID 26373282 DOI: 10.1186/s13024-015-0042-7  0.52
2015 Painter MM, Atagi Y, Liu CC, Rademakers R, Xu H, Fryer JD, Bu G. TREM2 in CNS homeostasis and neurodegenerative disease. Molecular Neurodegeneration. 10: 43. PMID 26337043 DOI: 10.1186/s13024-015-0040-9  0.52
2015 Harriott AM, Heckman MG, Rayaprolu S, Soto-Ortolaza AI, Diehl NN, Kanekiyo T, Liu CC, Bu G, Malik R, Cole JW, Meschia JF, Ross OA. Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 1235-41. PMID 26031789 DOI: 10.1111/ene.12735  0.52
2015 Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice. Molecular Neurodegeneration. 10: 6. PMID 25871773 DOI: 10.1186/s13024-015-0001-3  0.52
2015 Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G. Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5851-9. PMID 25855193 DOI: 10.1523/JNEUROSCI.5180-14.2015  0.52
2014 Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. Neuron. 84: 63-77. PMID 25242217 DOI: 10.1016/j.neuron.2014.08.048  0.52
2014 Liu CC, Kanekiyo T, Roth B, Bu G. Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling. The Journal of Biological Chemistry. 289: 27562-70. PMID 25143377 DOI: 10.1074/jbc.M113.533927  0.52
2014 Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G. Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway. The Journal of Biological Chemistry. 289: 11282-92. PMID 24599963 DOI: 10.1074/jbc.M113.526095  0.52
2013 Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Neuronal clearance of amyloid-β by endocytic receptor LRP1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19276-83. PMID 24305823 DOI: 10.1523/JNEUROSCI.3487-13.2013  0.52
2013 Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nature Reviews. Neurology. 9: 106-18. PMID 23296339 DOI: 10.1038/nrneurol.2012.263  0.52
2012 Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16458-65. PMID 23152628 DOI: 10.1523/JNEUROSCI.3987-12.2012  0.52
2011 Chen J, Liu CC, Li Q, Nowak C, Bu G, Wang J. Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. Structure (London, England : 1993). 19: 313-23. PMID 21397183 DOI: 10.1016/j.str.2011.01.010  0.52
2011 Kanekiyo T, Zhang J, Liu Q, Liu CC, Zhang L, Bu G. Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1644-51. PMID 21289173 DOI: 10.1523/JNEUROSCI.5491-10.2011  0.52
2010 Li Y, Lu W, King TD, Liu CC, Bijur GN, Bu G. Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation. Plos One. 5: e11014. PMID 20543981 DOI: 10.1371/journal.pone.0011014  0.52
2010 Chen J, Li Q, Liu CC, Zhou P, Zhou B, Bu G, Wang J. NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6. Journal of Biomolecular Nmr. 47: 283-8. PMID 20506034 DOI: 10.1007/s10858-010-9426-8  0.52
2010 Lu W, Liu CC, Thottassery JV, Bu G, Li Y. Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells. Biochemistry. 49: 4635-43. PMID 20446724 DOI: 10.1021/bi1001486  0.52
2010 Liu CC, Prior J, Piwnica-Worms D, Bu G. LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 5136-41. PMID 20194742 DOI: 10.1073/pnas.0911220107  0.52
2009 Liu CC, Pearson C, Bu G. Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains. The Journal of Biological Chemistry. 284: 15299-307. PMID 19339249 DOI: 10.1074/jbc.M807285200  0.52
2008 Bu G, Lu W, Liu CC, Selander K, Yoneda T, Hall C, Keller ET, Li Y. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. International Journal of Cancer. Journal International Du Cancer. 123: 1034-42. PMID 18546262 DOI: 10.1002/ijc.23625  0.52
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