Sheila A. Stewart - Publications

Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Cell Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Stewart SA, Yao Z, Murali B, Ren Q, Luo X, Faget DV, Cole T, Ricci B, Thotala D, Monahan J, van Deursen JM, Baker D, Faccio R, Schwarz JK. Therapy-induced senescence drives bone loss. Cancer Research. PMID 31932453 DOI: 10.1158/0008-5472.CAN-19-2348  0.48
2019 Faget DV, Ren Q, Stewart SA. Unmasking senescence: context-dependent effects of SASP in cancer. Nature Reviews. Cancer. PMID 31235879 DOI: 10.1038/s41568-019-0156-2  0.48
2018 Flanagan KC, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur LL, Tapia R, Stewart SA. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 9: 21-36. PMID 29416593 DOI: 10.18632/oncotarget.22940  0.72
2017 Nickless A, Cheruiyot A, Flanagan KC, Piwnica-Worms D, Stewart SA, You Z. p38 MAPK Inhibits Nonsense-mediated RNA Decay in Response to Persistent DNA Damage in Non-cycling Cells. The Journal of Biological Chemistry. PMID 28765281 DOI: 10.1074/jbc.M117.787846  0.48
2017 Parajuli S, Tealsey DC, Murali B, Jackson J, Vindigni A, Stewart SA. Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork. The Journal of Biological Chemistry. PMID 28717002 DOI: 10.1074/jbc.M117.787473  0.48
2016 Poppler L, Ee X, Schellhardt L, Hoben G, Pan D, Hunter D, Yan Y, Moore A, Snyder-Warwick A, Stewart S, Mackinnon SE, Wood MD. Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts. Tissue Engineering. Part A. PMID 27297909 DOI: 10.1089/ten.TEA.2016.0003  1
2016 Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, ... Stewart SA, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7: 11762. PMID 27272654 DOI: 10.1038/ncomms11762  1
2016 Marsh T, Wong I, Sceneay J, Barakat A, Qin Y, Sjödin A, Alspach E, Nilsson B, Stewart SA, McAllister SS. Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression. Cancer Research. 76: 2932-2943. PMID 27197230 DOI: 10.1158/0008-5472.CAN-15-3332  0.48
2016 D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R. Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer. The Journal of Experimental Medicine. PMID 27045006 DOI: 10.1084/jem.20150950  1
2016 Ruhland MK, Coussens LM, Stewart SA. Senescence and cancer: An evolving inflammatory paradox. Biochimica Et Biophysica Acta. 1865: 14-22. PMID 26453912 DOI: 10.1016/j.bbcan.2015.10.001  1
2015 Alspach E, Stewart SA. RNA-binding Protein Immunoprecipitation (RIP) to Examine AUF1 Binding to Senescence-Associated Secretory Phenotype (SASP) Factor mRNA. Bio-Protocol. 5. PMID 27453911  0.48
2015 Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, ... ... Stewart SA, et al. Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development. Cell Reports. PMID 26725121 DOI: 10.1016/j.celrep.2015.12.016  1
2015 Teasley DC, Parajuli S, Nguyen M, Moore HR, Alspach E, Lock YJ, Honaker Y, Saharia A, Piwnica-Worms H, Stewart SA. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. The Journal of Biological Chemistry. 290: 15133-45. PMID 25922071 DOI: 10.1074/jbc.M115.647388  1
2015 Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, Zellweger R, Moore H, Lee EH, Hendrickson EA, Cejka P, Stewart S, Lopes M, Vindigni A. DNA2 drives processing and restart of reversed replication forks in human cells. The Journal of Cell Biology. 208: 545-62. PMID 25733713 DOI: 10.1083/jcb.201406100  1
2014 Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA. p38MAPK plays a crucial role in stromal-mediated tumorigenesis. Cancer Discovery. 4: 716-29. PMID 24670723 DOI: 10.1158/2159-8290.CD-13-0743  1
2013 Alspach E, Fu Y, Stewart SA. Senescence and the pro-tumorigenic stroma. Critical Reviews in Oncogenesis. 18: 549-58. PMID 24579734 DOI: 10.1615/CritRevOncog.2014010630  1
2013 Saheb-Al-Zamani M, Yan Y, Farber SJ, Hunter DA, Newton P, Wood MD, Stewart SA, Johnson PJ, Mackinnon SE. Limited regeneration in long acellular nerve allografts is associated with increased Schwann cell senescence. Experimental Neurology. 247: 165-77. PMID 23644284 DOI: 10.1016/j.expneurol.2013.04.011  1
2013 Faccio R, Capietto AH, Stewart SA, Novack DV. Cellular players in breast cancer bone metastases Clinical Reviews in Bone and Mineral Metabolism. 11: 122-132. DOI: 10.1007/s12018-013-9146-1  1
2012 Karanja KK, Cox SW, Duxin JP, Stewart SA, Campbell JL. DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network. Cell Cycle (Georgetown, Tex.). 11: 3983-96. PMID 22987153 DOI: 10.4161/cc.22215  1
2012 Duxin JP, Moore HR, Sidorova J, Karanja K, Honaker Y, Dao B, Piwnica-Worms H, Campbell JL, Monnat RJ, Stewart SA. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. The Journal of Biological Chemistry. 287: 21980-91. PMID 22570476 DOI: 10.1074/jbc.M112.359018  1
2012 Pazolli E, Alspach E, Milczarek A, Prior J, Piwnica-Worms D, Stewart SA. Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression. Cancer Research. 72: 2251-61. PMID 22422937 DOI: 10.1158/0008-5472.CAN-11-3386  1
2011 Luo X, Ruhland MK, Pazolli E, Lind AC, Stewart SA. Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway. Molecular Cancer Research : McR. 9: 1018-29. PMID 21673011 DOI: 10.1158/1541-7786.MCR-10-0472  1
2010 Stewart SA, Bertuch AA. The role of telomeres and telomerase in cancer research. Cancer Research. 70: 7365-71. PMID 20841475 DOI: 10.1158/0008-5472.CAN-10-1373  1
2010 Saharia A, Teasley DC, Duxin JP, Dao B, Chiappinelli KB, Stewart SA. FEN1 ensures telomere stability by facilitating replication fork re-initiation. The Journal of Biological Chemistry. 285: 27057-66. PMID 20551483 DOI: 10.1074/jbc.M110.112276  1
2010 Nittis T, Guittat L, LeDuc RD, Dao B, Duxin JP, Rohrs H, Townsend RR, Stewart SA. Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS. Molecular & Cellular Proteomics : McP. 9: 1144-56. PMID 20097687 DOI: 10.1074/mcp.M900490-MCP200  1
2009 Duxin JP, Dao B, Martinsson P, Rajala N, Guittat L, Campbell JL, Spelbrink JN, Stewart SA. Human Dna2 is a nuclear and mitochondrial DNA maintenance protein. Molecular and Cellular Biology. 29: 4274-82. PMID 19487465 DOI: 10.1128/MCB.01834-08  1
2009 Pazolli E, Luo X, Brehm S, Carbery K, Chung JJ, Prior JL, Doherty J, Demehri S, Salavaggione L, Piwnica-Worms D, Stewart SA. Senescent stromal-derived osteopontin promotes preneoplastic cell growth. Cancer Research. 69: 1230-9. PMID 19155301 DOI: 10.1158/0008-5472.CAN-08-2970  1
2009 Saharia A, Stewart SA. FEN1 contributes to telomere stability in ALT-positive tumor cells. Oncogene. 28: 1162-7. PMID 19137021 DOI: 10.1038/onc.2008.458  1
2008 Nyström AM, Xu Z, Xu J, Taylor S, Nittis T, Stewart SA, Leonard J, Wooley KL. SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles. Chemical Communications (Cambridge, England). 3579-81. PMID 18654719 DOI: 10.1039/b805428b  1
2008 Saharia A, Guittat L, Crocker S, Lim A, Steffen M, Kulkarni S, Stewart SA. Flap endonuclease 1 contributes to telomere stability. Current Biology : Cb. 18: 496-500. PMID 18394896 DOI: 10.1016/j.cub.2008.02.071  1
2008 Pazolli E, Stewart SA. Senescence: the good the bad and the dysfunctional. Current Opinion in Genetics & Development. 18: 42-7. PMID 18262406 DOI: 10.1016/j.gde.2007.12.002  1
2008 Nittis T, Guittat L, Stewart SA. Alternative lengthening of telomeres (ALT) and chromatin: is there a connection? Biochimie. 90: 5-12. PMID 17935854 DOI: 10.1016/j.biochi.2007.08.009  1
2006 Stewart SA, Weinberg RA. Telomeres: cancer to human aging. Annual Review of Cell and Developmental Biology. 22: 531-57. PMID 16824017 DOI: 10.1146/annurev.cellbio.22.010305.104518  1
2006 Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell. 124: 1283-98. PMID 16564017 DOI: 10.1016/j.cell.2006.01.040  1
2005 Stewart SA. Telomere maintenance and tumorigenesis: an "ALT"ernative road. Current Molecular Medicine. 5: 253-7. PMID 15974880 DOI: 10.2174/1566524053586653  1
2005 Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, Daley GQ. High-efficiency RNA interference in human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 299-305. PMID 15749924 DOI: 10.1634/stemcells.2004-0252  1
2003 Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC. Telomerase maintains telomere structure in normal human cells. Cell. 114: 241-53. PMID 12887925 DOI: 10.1016/S0092-8674(03)00550-6  1
2003 Stewart SA, Ben-Porath I, Carey VJ, O'Connor BF, Hahn WC, Weinberg RA. Erosion of the telomeric single-strand overhang at replicative senescence. Nature Genetics. 33: 492-6. PMID 12652299 DOI: 10.1038/ng1127  1
2003 Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Lentivirus-delivered stable gene silencing by RNAi in primary cells. Rna (New York, N.Y.). 9: 493-501. PMID 12649500 DOI: 10.1261/rna.2192803  1
2002 Stewart SA. Multiple levels of telomerase regulation. Molecular Interventions. 2: 481-3. PMID 14993399 DOI: 10.1124/mi.2.8.481  1
2002 Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 99: 12606-11. PMID 12193655 DOI: 10.1073/pnas.182407599  1
2002 Stewart SA, Hahn WC. Prospects for anti-neoplastic therapies based on telomere biology. Current Cancer Drug Targets. 2: 1-17. PMID 12188917 DOI: 10.2174/1568009023334015  1
2002 Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC. Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene. 21: 4577-86. PMID 12085236 DOI: 10.1038/sj.onc.1205550  1
2002 Stewart SA, Weinberg RA. Senescence: does it all happen at the ends? Oncogene. 21: 627-30. PMID 11850788 DOI: 10.1038/sj.onc.1205062  1
2002 Yang OO, Nguyen PT, Kalams SA, Dorfman T, Göttlinger HG, Stewart S, Chen IS, Threlkeld S, Walker BD. Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes. Journal of Virology. 76: 1626-31. PMID 11799157 DOI: 10.1128/JVI.76.4.1626-1631.2002  1
2001 Johnson FB, Marciniak RA, McVey M, Stewart SA, Hahn WC, Guarente L. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. The Embo Journal. 20: 905-13. PMID 11179234 DOI: 10.1093/emboj/20.4.905  1
2000 Stewart SA, Weinberg RA. Telomerase and human tumorigenesis Seminars in Cancer Biology. 10: 399-406. PMID 11170862 DOI: 10.1006/scbi.2000.0339  1
2000 Stewart SA, Poon B, Song JY, Chen ISY. Human immunodeficiency virus type 1 Vpr induces apoptosis through caspase activation Journal of Virology. 74: 3105-3111. PMID 10708425 DOI: 10.1128/JVI.74.7.3105-3111.2000  1
1999 Stewart SA, Poon B, Jowett JBM, Xie Y, Chen ISY. Lentiviral delivery of HIV-1 Vpr protein induces apoptosis in transformed cells Proceedings of the National Academy of Sciences of the United States of America. 96: 12039-12043. PMID 10518572 DOI: 10.1073/pnas.96.21.12039  1
1999 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Inhibition of telomerase limits the growth of human cancer cells. Nature Medicine. 5: 1164-70. PMID 10502820 DOI: 10.1038/13495  1
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