Douglas Hanahan - Publications

Affiliations: 
Cell Biology University of California, San Francisco, San Francisco, CA 
Area:
Genetics, Cell Biology, Oncology

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Allen E, Miéville P, Warren CM, Saghafinia S, Li L, Peng MW, Hanahan D. Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling. Cell Reports. PMID 27134166 DOI: 10.1016/j.celrep.2016.04.029  0.44
2015 Guinney J, Dienstmann R, Wang X, de Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, ... ... Hanahan D, et al. The consensus molecular subtypes of colorectal cancer. Nature Medicine. PMID 26457759 DOI: 10.1038/nm.3967  0.44
2015 Sadanandam A, Wullschleger S, Lyssiotis CA, Grotzinger C, Barbi S, Bersani S, Korner J, Wafy I, Mafficini A, Lawlor RT, Simbolo M, Asara JM, Blaker H, Cantley LC, Wiedenmann B, ... ... Hanahan D, et al. A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics. Cancer Discovery. PMID 26446169 DOI: 10.1158/2159-8290.CD-15-0068  0.44
2015 Shchors K, Massaras A, Hanahan D. Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit. Cancer Cell. 28: 456-71. PMID 26412325 DOI: 10.1016/j.ccell.2015.08.012  0.44
2015 Brindle NR, Joyce JA, Rostker F, Lawlor ER, Swigart-Brown L, Evan G, Hanahan D, Shchors K. Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer. Plos One. 10: e0120348. PMID 25927437 DOI: 10.1371/journal.pone.0120348  0.44
2014 Sadanandam A, Gray J, Hanahan D. Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response. Nature Medicine. 20: 1231-2. PMID 25375919 DOI: 10.1038/nm.3742  0.44
2014 Sadanandam A, Wang X, de Sousa E Melo F, Gray JW, Vermeulen L, Hanahan D, Medema JP. Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications. Cell Cycle (Georgetown, Tex.). 13: 353-7. PMID 24406433 DOI: 10.4161/cc.27769  0.44
2014 Hanahan D. Rethinking the war on cancer. Lancet. 383: 558-63. PMID 24351321 DOI: 10.1016/S0140-6736(13)62226-6  0.44
2014 Powolny F, Homicsko K, Sinisi R, Bruschini CE, Grigoriev E, Homulle H, Prior JO, Hanahan D, Dubikovskaya E, Charbon E. Time-resolved imaging system for fluorescence-guided surgery with lifetime imaging capability Proceedings of Spie - the International Society For Optical Engineering. 9129. DOI: 10.1117/12.2052411  0.44
2013 De Palma M, Coukos G, Hanahan D. A new twist on radiation oncology: low-dose irradiation elicits immunostimulatory macrophages that unlock barriers to tumor immunotherapy. Cancer Cell. 24: 559-61. PMID 24229704 DOI: 10.1016/j.ccr.2013.10.019  0.44
2013 Ishida S, Andreux P, Poitry-Yamate C, Auwerx J, Hanahan D. Bioavailable copper modulates oxidative phosphorylation and growth of tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: 19507-12. PMID 24218578 DOI: 10.1073/pnas.1318431110  0.44
2013 Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, et al. Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. Cancer Cell. 24: 379-93. PMID 24029234 DOI: 10.1016/j.ccr.2013.08.003  0.44
2013 Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R. Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia (New York, N.Y.). 15: 684-93. PMID 23814481 DOI: 10.1593/neo.13276  0.44
2013 Hunter KE, Quick ML, Sadanandam A, Hanahan D, Joyce JA. Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis. Plos One. 8: e64472. PMID 23691228 DOI: 10.1371/journal.pone.0064472  0.44
2013 Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, Ostos LC, Lannon WA, Grotzinger C, Del Rio M, Lhermitte B, Olshen AB, Wiedenmann B, Cantley LC, Gray JW, ... Hanahan D, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nature Medicine. 19: 619-25. PMID 23584089 DOI: 10.1038/nm.3175  0.44
2013 Shchors K, Persson AI, Rostker F, Tihan T, Lyubynska N, Li N, Swigart LB, Berger MS, Hanahan D, Weiss WA, Evan GI. Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy. Proceedings of the National Academy of Sciences of the United States of America. 110: E1480-9. PMID 23542378 DOI: 10.1073/pnas.1219142110  0.44
2013 Li L, Hanahan D. Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion. Cell. 153: 86-100. PMID 23540692 DOI: 10.1016/j.cell.2013.02.051  0.44
2013 Godinat A, Park HM, Miller SC, Cheng K, Hanahan D, Sanman LE, Bogyo M, Yu A, Nikitin GF, Stahl A, Dubikovskaya EA. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. Acs Chemical Biology. 8: 987-99. PMID 23463944 DOI: 10.1021/cb3007314  0.44
2013 Shchors K, Nozawa H, Xu J, Rostker F, Swigart-Brown L, Evan G, Hanahan D. Increased invasiveness of MMP-9-deficient tumors in two mouse models of neuroendocrine tumorigenesis. Oncogene. 32: 502-13. PMID 22391572 DOI: 10.1038/onc.2012.60  0.44
2012 Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell. 21: 309-22. PMID 22439926 DOI: 10.1016/j.ccr.2012.02.022  0.44
2012 De Palma M, Hanahan D. The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities. Molecular Oncology. 6: 111-27. PMID 22360993 DOI: 10.1016/j.molonc.2012.01.011  0.44
2011 Olson P, Chu GC, Perry SR, Nolan-Stevaux O, Hanahan D. Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 108: E1275-84. PMID 22084065 DOI: 10.1073/pnas.1111079108  0.44
2011 Pere H, Montier Y, Bayry J, Quintin-Colonna F, Merillon N, Dransart E, Badoual C, Gey A, Ravel P, Marcheteau E, Batteux F, Sandoval F, Adotevi O, Chiu C, Garcia S, ... ... Hanahan D, et al. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens. Blood. 118: 4853-62. PMID 21908423 DOI: 10.1182/blood-2011-01-329656  0.44
2011 Franco M, Roswall P, Cortez E, Hanahan D, Pietras K. Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood. 118: 2906-17. PMID 21778339 DOI: 10.1182/blood-2011-01-331694  0.44
2011 Falcon BL, Pietras K, Chou J, Chen D, Sennino B, Hanahan D, McDonald DM. Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B. The American Journal of Pathology. 178: 2920-30. PMID 21641409 DOI: 10.1016/j.ajpath.2011.02.019  0.44
2011 Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 9939-44. PMID 21622854 DOI: 10.1073/pnas.1105041108  0.44
2011 Allen E, Walters IB, Hanahan D. Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5299-310. PMID 21622725 DOI: 10.1158/1078-0432.CCR-10-2847  0.44
2011 Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L. Endogenous Myc maintains the tumor microenvironment. Genes & Development. 25: 907-16. PMID 21478273 DOI: 10.1101/gad.2038411  0.44
2011 Collisson EA, Sadanandam A, Olson P, Gibb WJ, Truitt M, Gu S, Cooc J, Weinkle J, Kim GE, Jakkula L, Feiler HS, Ko AH, Olshen AB, Danenberg KL, Tempero MA, ... ... Hanahan D, et al. Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nature Medicine. 17: 500-3. PMID 21460848 DOI: 10.1038/nm.2344  0.44
2011 Tuveson D, Hanahan D. Translational medicine: Cancer lessons from mice to humans. Nature. 471: 316-7. PMID 21412332 DOI: 10.1038/471316a  0.44
2011 Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 144: 646-74. PMID 21376230 DOI: 10.1016/j.cell.2011.02.013  0.44
2010 Nolan-Stevaux O, Truitt MC, Pahler JC, Olson P, Guinto C, Lee DC, Hanahan D. Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes. Genes & Cancer. 1: 125-41. PMID 20975924 DOI: 10.1177/1947601909358722  0.44
2010 Chun MG, Hanahan D. Genetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis. Plos Genetics. 6: e1001120. PMID 20862307 DOI: 10.1371/journal.pgen.1001120  0.44
2010 Chun MG, Mao JH, Chiu CW, Balmain A, Hanahan D. Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17268-73. PMID 20855625 DOI: 10.1073/pnas.1012705107  0.44
2010 Chiu CW, Nozawa H, Hanahan D. Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4425-33. PMID 20823411 DOI: 10.1200/JCO.2010.28.0198  0.44
2010 Ulanet DB, Hanahan D. Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms. Plos One. 5: e12454. PMID 20805995 DOI: 10.1371/journal.pone.0012454  0.44
2010 Ishida S, McCormick F, Smith-McCune K, Hanahan D. Enhancing tumor-specific uptake of the anticancer drug cisplatin with a copper chelator. Cancer Cell. 17: 574-83. PMID 20541702 DOI: 10.1016/j.ccr.2010.04.011  0.44
2010 Ulanet DB, Ludwig DL, Kahn CR, Hanahan D. Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 10791-8. PMID 20457905 DOI: 10.1073/pnas.0914076107  0.44
2010 Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. Cancer Cell. 17: 135-47. PMID 20138012 DOI: 10.1016/j.ccr.2009.12.041  0.44
2010 Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner (DOI:10.1016/j.ccr.2009.12.041) Cancer Cell. 17: 523. DOI: 10.1016/j.ccr.2010.04.018  0.44
2009 Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Girard OM, Hanahan D, Mattrey RF, Ruoslahti E. Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell. 16: 510-20. PMID 19962669 DOI: 10.1016/j.ccr.2009.10.013  0.44
2009 Olson P, Lu J, Zhang H, Shai A, Chun MG, Wang Y, Libutti SK, Nakakura EK, Golub TR, Hanahan D. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes & Development. 23: 2152-65. PMID 19759263 DOI: 10.1101/gad.1820109  0.44
2009 Olson P, Hanahan D. Cancer. Breaching the cancer fortress. Science (New York, N.Y.). 324: 1400-1. PMID 19520948 DOI: 10.1126/science.1175940  0.44
2009 Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, Inoue M, Bergers G, Hanahan D, Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell. 15: 220-31. PMID 19249680 DOI: 10.1016/j.ccr.2009.01.027  0.44
2009 Hager JH, Ulanet DB, Hennighausen L, Hanahan D. Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer. Plos One. 4: e4455. PMID 19209227 DOI: 10.1371/journal.pone.0004455  0.44
2009 Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernández-Zapico ME, Hanahan D. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes & Development. 23: 24-36. PMID 19136624 DOI: 10.1101/gad.1753809  0.44
2008 Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nature Reviews. Cancer. 8: 592-603. PMID 18650835 DOI: 10.1038/nrc2442  0.44
2008 Pahler JC, Tazzyman S, Erez N, Chen YY, Murdoch C, Nozawa H, Lewis CE, Hanahan D. Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia (New York, N.Y.). 10: 329-40. PMID 18392134 DOI: 10.1593/neo.07871  0.44
2008 Hanahan D, Weinberg RA. Retrospective: Judah Folkman (1933-2008). Science (New York, N.Y.). 319: 1055. PMID 18292332 DOI: 10.1126/science.1156080  0.44
2008 Bishop JM, Hanahan D, Tlsty T, Hunter T, Lowe S, Varmus H, Dornbush KT, Waring JF, Jacks T, Gilmer T, Sherman M, Gerritsen W, Curran T, Doroshow J, Barrett JC, et al. The 20th Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy 2005 Molecular Carcinogenesis. 47: 707-732. PMID 18286481 DOI: 10.1002/mc.20214  0.44
2008 Pietras K, Pahler J, Bergers G, Hanahan D. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. Plos Medicine. 5: e19. PMID 18232728 DOI: 10.1371/journal.pmed.0050019  0.44
2008 Hanahan D. Perspectives on the future of angiogenesis research Angiogenesis: An Integrative Approach From Science to Medicine. 575-583. DOI: 10.1007/978-0-387-71518-6_48  0.44
2007 Du YC, Lewis BC, Hanahan D, Varmus H. Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion. Plos Biology. 5: e276. PMID 17941720 DOI: 10.1371/journal.pbio.0050276  0.44
2007 Hanahan D, Wagner EF, Palmiter RD. The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer. Genes & Development. 21: 2258-70. PMID 17875663 DOI: 10.1101/gad.1583307  0.44
2007 Bell-McGuinn KM, Garfall AL, Bogyo M, Hanahan D, Joyce JA. Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer. Cancer Research. 67: 7378-85. PMID 17671208 DOI: 10.1158/0008-5472.CAN-07-0602  0.44
2006 Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, DePinho RA. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes & Development. 20: 3130-46. PMID 17114584 DOI: 10.1101/gad.1478706  0.44
2006 Nozawa H, Chiu C, Hanahan D. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 12493-8. PMID 16891410 DOI: 10.1073/pnas.0601807103  0.44
2006 Zhang L, Giraudo E, Hoffman JA, Hanahan D, Ruoslahti E. Lymphatic zip codes in premalignant lesions and tumors. Cancer Research. 66: 5696-706. PMID 16740707 DOI: 10.1158/0008-5472.CAN-05-3876  0.44
2006 Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 103: 5947-52. PMID 16585505 DOI: 10.1073/pnas.0601273103  0.44
2006 Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes & Development. 20: 543-56. PMID 16481467 DOI: 10.1101/gad.1407406  0.44
2006 Giraudo E, Hanahan D. Zoledronic acid inhibit angiogenesis and impairs tumorigenesis in a mouse model of cervical carcinogenesis Haematologica Reports. 2: 39-41.  0.44
2005 Casanovas O, Hicklin DJ, Bergers G, Hanahan D. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell. 8: 299-309. PMID 16226705 DOI: 10.1016/j.ccr.2005.09.005  0.44
2005 Garcia CA, Prabakar KR, Diez J, Cao ZA, Allende G, Zeller M, Dogra R, Mendez A, Rosenkranz E, Dahl U, Ricordi C, Hanahan D, Pugliese A. Dendritic cells in human thymus and periphery display a proinsulin epitope in a transcription-dependent, capture-independent fashion. Journal of Immunology (Baltimore, Md. : 1950). 175: 2111-22. PMID 16081777  0.44
2005 Casanovas O, Hager JH, Chun MG, Hanahan D. Incomplete inhibition of the Rb tumor suppressor pathway in the context of inactivated p53 is sufficient for pancreatic islet tumorigenesis. Oncogene. 24: 6597-604. PMID 16007165 DOI: 10.1038/sj.onc.1208823  0.44
2005 Joyce JA, Freeman C, Meyer-Morse N, Parish CR, Hanahan D. A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer. Oncogene. 24: 4037-51. PMID 15806157 DOI: 10.1038/sj.onc.1208602  0.44
2005 Daniel D, Chiu C, Giraudo E, Inoue M, Mizzen LA, Chu NR, Hanahan D. CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer. Cancer Research. 65: 2018-25. PMID 15753402 DOI: 10.1158/0008-5472.CAN-04-3444  0.44
2005 Pietras K, Hanahan D. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 939-52. PMID 15557593 DOI: 10.1200/JCO.2005.07.093  0.44
2004 Joyce JA, Hanahan D. Multiple roles for cysteine cathepsins in cancer. Cell Cycle (Georgetown, Tex.). 3: 1516-619. PMID 15539953  0.44
2004 Argilla D, Chin K, Singh M, Hodgson JG, Bosenberg M, de Solórzano CO, Lockett S, DePinho RA, Gray J, Hanahan D. Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes. Cancer Cell. 6: 373-85. PMID 15488760 DOI: 10.1016/j.ccr.2004.08.032  0.44
2004 Astrof S, Crowley D, George EL, Fukuda T, Sekiguchi K, Hanahan D, Hynes RO. Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Molecular and Cellular Biology. 24: 8662-70. PMID 15367684 DOI: 10.1128/MCB.24.19.8662-8670.2004  0.44
2004 Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, Tsai FY, Greenbaum DC, Hager JH, Bogyo M, Hanahan D. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell. 5: 443-53. PMID 15144952 DOI: 10.1016/S1535-6108(04)00111-4  0.44
2004 Hager JH, Hodgson JG, Fridlyand J, Hariono S, Gray JW, Hanahan D. Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas. Cancer Research. 64: 2406-10. PMID 15059892 DOI: 10.1158/0008-5472.CAN-03-3522  0.44
2004 McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 161-75. PMID 14770088  0.44
2004 Giraudo E, Inoue M, Hanahan D. An amino-bisphosphonate targets MMP-9 - Expressing macrophages and angiogenesis to impair cervical carcinogenesis Journal of Clinical Investigation. 114: 623-633. DOI: 10.1172/JCI200422087  0.44
2003 Joyce JA, Laakkonen P, Bernasconi M, Bergers G, Ruoslahti E, Hanahan D. Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 4: 393-403. PMID 14667506 DOI: 10.1016/S1535-6108(03)00271-X  0.44
2003 Hoffman JA, Giraudo E, Singh M, Zhang L, Inoue M, Porkka K, Hanahan D, Ruoslahti E. Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma. Cancer Cell. 4: 383-91. PMID 14667505 DOI: 10.1016/S1535-6108(03)00273-3  0.44
2003 Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, et al. Of mice and MEN1: Insulinomas in a conditional mouse knockout. Molecular and Cellular Biology. 23: 6075-85. PMID 12917331 DOI: 10.1128/MCB.23.17.6075-6085.2003  0.44
2003 Hanahan D, Lanzavecchia A, Mihich E. Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors. Cancer Research. 63: 3005-8. PMID 12782611  0.44
2003 Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. The Journal of Clinical Investigation. 111: 1287-95. PMID 12727920 DOI: 10.1172/JCI17929  0.44
2003 Daniel D, Meyer-Morse N, Bergsland EK, Dehne K, Coussens LM, Hanahan D. Immune enhancement of skin carcinogenesis by CD4+ T cells. The Journal of Experimental Medicine. 197: 1017-28. PMID 12695493 DOI: 10.1084/jem.20021047  0.44
2002 Bergers G, Hanahan D. Combining antiangiogenic agents with metronomic chemotherapy enhances efficacy against late-stage pancreatic islet carcinomas in mice. Cold Spring Harbor Symposia On Quantitative Biology. 67: 293-300. PMID 12858552  0.44
2002 Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 1: 339-53. PMID 12086849 DOI: 10.1016/S1535-6108(02)00055-7  0.44
2002 Man S, Bocci G, Francia G, Green SK, Jothy S, Hanahan D, Bohlen P, Hicklin DJ, Bergers G, Kerbel RS. Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. Cancer Research. 62: 2731-5. PMID 12019144  0.44
2002 Cao ZA, Daniel D, Hanahan D. Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer. Bmc Cancer. 2: 11. PMID 12019035 DOI: 10.1186/1471-2407-2-11  0.44
2002 Inoue M, Hager JH, Ferrara N, Gerber HP, Hanahan D. VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis Cancer Cell. 1: 193-202. DOI: 10.1016/S1535-6108(02)00031-4  0.44
2001 Hodgson G, Hager JH, Volik S, Hariono S, Wernick M, Moore D, Nowak N, Albertson DG, Pinkel D, Collins C, Hanahan D, Gray JW. Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nature Genetics. 29: 459-64. PMID 11694878 DOI: 10.1038/ng771  0.44
2001 Qian F, Hanahan D, Weissman IL. L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 3976-81. PMID 11274419 DOI: 10.1073/pnas.061633698  0.44
2001 Bergers G, Hanahan D. Cell factories for fighting cancer. Nature Biotechnology. 19: 20-1. PMID 11135544 DOI: 10.1038/83457  0.44
2000 Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell. 103: 481-90. PMID 11081634  0.44
2000 Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nature Cell Biology. 2: 737-44. PMID 11025665 DOI: 10.1038/35036374  0.44
2000 Shi Y, Kanaani J, Menard-Rose V, Ma YH, Chang PY, Hanahan D, Tobin A, Grodsky G, Baekkeskov S. Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 279: E684-94. PMID 10950838  0.44
2000 Hanahan D. Benefits of bad telomeres. Nature. 406: 573-4. PMID 10949281 DOI: 10.1038/35020662  0.44
2000 Luther SA, Lopez T, Bai W, Hanahan D, Cyster JG. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity. 12: 471-81. PMID 10843380  0.44
2000 Hanahan D, Bergers G, Bergsland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. The Journal of Clinical Investigation. 105: 1045-7. PMID 10772648 DOI: 10.1172/JCI9872  0.44
2000 Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS. Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 278: E340-51. PMID 10662719  0.44
2000 Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 100: 57-70. PMID 10647931 DOI: 10.1016/S0092-8674(00)81683-9  0.44
1999 Hager JH, Hanahan D. Tumor cells utilize multiple pathways to down-modulate apoptosis. Lessons from a mouse model of islet cell carcinogenesis. Annals of the New York Academy of Sciences. 887: 150-63. PMID 10668471  0.44
1999 Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR. Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines. The Journal of Clinical Investigation. 104: R69-75. PMID 10606633 DOI: 10.1172/JCI8339  0.44
1999 Coussens LM, Raymond WW, Bergers G, Laig-Webster M, Behrendtsen O, Werb Z, Caughey GH, Hanahan D. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes & Development. 13: 1382-97. PMID 10364156  0.44
1999 Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science (New York, N.Y.). 284: 808-12. PMID 10221914 DOI: 10.1126/science.284.5415.808  0.44
1999 Grunstein J, Roberts WG, Mathieu-Costello O, Hanahan D, Johnson RS. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Research. 59: 1592-8. PMID 10197634  0.44
1998 Hanahan D. Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity. Current Opinion in Immunology. 10: 656-62. PMID 9914224 DOI: 10.1016/S0952-7915(98)80085-X  0.44
1998 Bergers G, Hanahan D, Coussens LM. Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis. The International Journal of Developmental Biology. 42: 995-1002. PMID 9853830  0.44
1998 Ganss R, Hanahan D. Tumor microenvironment can restrict the effectiveness of activated antitumor lymphocytes. Cancer Research. 58: 4673-81. PMID 9788621  0.44
1998 Olson DC, Deng C, Hanahan D. Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 557-64. PMID 9690623  0.44
1998 Vu TH, Shipley JM, Bergers G, Berger JE, Helms JA, Hanahan D, Shapiro SD, Senior RM, Werb Z. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell. 93: 411-22. PMID 9590175 DOI: 10.1016/S0092-8674(00)81169-1  0.44
1998 Hanahan D. A flanking attack on cancer Nature Medicine. 4: 13. PMID 9427594 DOI: 10.1038/nm0198-013  0.44
1998 Laig-Webster M, Coussens LM, Hanahan D, Caughey GH. A general method for genotyping mast cell-deficient KITW/KITWυ mice by allele-specific polymerase chain reaction Faseb Journal. 12: A895.  0.44
1997 Blasco MA, Lee HW, Rizen M, Hanahan D, DePinho R, Greider CW. Mouse models for the study of telomerase. Ciba Foundation Symposium. 211: 160-70; discussion 1. PMID 9524757  0.44
1997 Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14060-5. PMID 9391152 DOI: 10.1073/pnas.94.25.14060  0.44
1997 Shi YP, Mohapatra G, Miller J, Hanahan D, Lander E, Gold P, Pinkel D, Gray J. FISH probes for mouse chromosome identification Genomics. 45: 42-47. PMID 9339359 DOI: 10.1006/geno.1997.4904  0.44
1997 Smith KM, Olson DC, Hirose R, Hanahan D. Pancreatic gene expression in rare cells of thymic medulla: Evidence for functional contribution to T cell tolerance International Immunology. 9: 1355-1365. PMID 9310839 DOI: 10.1093/intimm/9.9.1355  0.44
1997 Damert A, Machein M, Breier G, Fujita MQ, Hanahan D, Risau W, Plate KH. Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms Cancer Research. 57: 3860-3864. PMID 9288800  0.44
1997 Speiser DE, Miranda R, Zakarian A, Bachmann MF, McKall-Faienza K, Odermatt B, Hanahan D, Zinkernagel RM, Ohashi PS. Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy. The Journal of Experimental Medicine. 186: 645-53. PMID 9271580 DOI: 10.1084/jem.186.5.645  0.44
1997 Hanahan D. Signaling vascular morphogenesis and maintenance Science. 277: 48-50. PMID 9229772 DOI: 10.1126/science.277.5322.48  0.44
1997 Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, Baekkeskov S. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction Nature Medicine. 3: 738-743. PMID 9212099 DOI: 10.1038/nm0797-738  0.44
1997 Shi YP, Naik P, Dietrich WF, Gray JW, Hanahan D, Pinkel D. DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice Genes Chromosomes and Cancer. 19: 104-111. PMID 9172001 DOI: 10.1002/(SICI)1098-2264(199706)19:2<104::AID-GCC6>3.0.CO;2-2  0.44
1997 Smith-McCune K, Zhu YH, Hanahan D, Arbeit J. Cross-species comparison of angiogenesis during the premalignant stages of squamous carcinogenesis in the human cervix and K14-HPV16 transgenic mice Cancer Research. 57: 1294-1300. PMID 9102216  0.44
1997 Gittes GK, Hanahan DA, Rutter WJ. Early events in β-cell lineage determination Experimental and Clinical Endocrinology and Diabetes. 105: A18-A19.  0.44
1996 Hanahan D, Christofori G, Naik P, Arbeit J. Transgenic mouse models of tumour angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models European Journal of Cancer Part A. 32: 2386-2393. PMID 9059326 DOI: 10.1016/S0959-8049(96)00401-7  0.44
1996 Coussens LM, Hanahan D, Arbeit JM. Genetic predisposition and parameters of malignant progression in K14- HPV16 transgenic mice American Journal of Pathology. 149: 1899-1917. PMID 8952526  0.44
1996 Arbeit JM, Olson DC, Hanahan D. Upregulation of fibroblast growth factors and their receptors during multistage epidermal carcinogenesis in K14-HPV16 transgenic mice Oncogene. 13: 1847-1857. PMID 8934530  0.44
1996 Naik P, Karrim J, Hanahan D. The rise and fall of apoptosis during multistage tumorigenesis: Down- modulation contributes to tumor progression from angiogenic progenitors Genes and Development. 10: 2105-2116. PMID 8804306  0.44
1996 Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell. 86: 353-364. PMID 8756718 DOI: 10.1016/S0092-8674(00)80108-7  0.44
1996 Johnson R, Spiegelman B, Hanahan D, Wisdom R. Cellular transformation and malignancy induced by ras require c-jun Molecular and Cellular Biology. 16: 4504-4511. PMID 8754851  0.44
1996 Parangi S, O'Reilly M, Christofori G, Holmgren L, Grosfeld J, Folkman J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth Proceedings of the National Academy of Sciences of the United States of America. 93: 2002-2007. PMID 8700875 DOI: 10.1073/pnas.93.5.2002  0.44
1996 Gittes GK, Galante PE, Hanahan D, Rutter WJ, Debase HT. Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors. Development (Cambridge, England). 122: 439-47. PMID 8625795  0.44
1996 Arbeit JM, Howley PM, Hanahan D. Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 93: 2930-2935. PMID 8610145 DOI: 10.1073/pnas.93.7.2930  0.44
1996 Blasco MA, Rizen M, Greider CW, Hanahan D. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nature Genetics. 12: 200-4. PMID 8563761 DOI: 10.1038/ng0296-200  0.44
1996 Onrust SV, Hartl PM, Rosen SD, Hanahan D. Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice Journal of Clinical Investigation. 97: 54-64. PMID 8550850  0.44
1995 Christofori G, Naik P, Hanahan D. Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis Molecular Endocrinology. 9: 1760-1770. PMID 8614412  0.44
1995 Hurlin PJ, Foley KP, Ayer DE, Eisenman RN, Hanahan D, Arbeit JM. Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis. Oncogene. 11: 2487-501. PMID 8545105  0.44
1995 Parangi S, Dietrich W, Christofori G, Lander ES, Hanahan D. Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma Cancer Research. 55: 6071-6076. PMID 8521395  0.44
1995 Vivanco MD, Johnson R, Galante PE, Hanahan D, Yamamoto KR. A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development. The Embo Journal. 14: 2217-28. PMID 7774580  0.44
1995 Christofori G, Naik P, Hanahan D. Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during β-cell tumorigenesis Nature Genetics. 10: 196-201. PMID 7663515 DOI: 10.1038/ng0695-196  0.44
1995 Raleigh EA, Murray NE, Revel H, Blumenthal RM, Westaway D, Reith AD, Rigby PWJ, Elhai J, Hanahan D. McrA and McrB restriction phenotypes of some E.coli strains and implications for gene cloning Nucleic Acids Research. 23: 3612. DOI: 10.1093/nar/23.17.3612  0.44
1995 Raleigh EA, Murray NE, Revel H, Blumenthal RM, Westaway D, Reith AD, Rigby PWJ, Elhai J, Hanahan D. Corrigendum: McrA and McrB restriction phenotypes of some E.coli strains and implications for gene cloning (Nucleic Acids Research (1988) 15 (1563-1575)) Nucleic Acids Research. 23: 3612.  0.44
1994 Christofori G, Hanahan D. Molecular dissection of multi-stage tumorigenesis in transgenic mice Seminars in Cancer Biology. 5: 3-12. PMID 8186386  0.44
1994 Jolicoeur C, Hanahan D, Smith KM. T-cell tolerance toward a transgenic β-cell antigen and transcription of endogenous pancreatic genes in thymus Proceedings of the National Academy of Sciences of the United States of America. 91: 6707-6711. PMID 8022837 DOI: 10.1073/pnas.91.14.6707  0.44
1994 Dietrich WF, Radany EH, Smith JS, Bishop JM, Hanahan D, Lander ES. Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16 Proceedings of the National Academy of Sciences of the United States of America. 91: 9451-9455. PMID 7937788  0.44
1994 Christofori G, Naik P, Hanahan D. A second signal supplied by insulin-like growth factor II in oncogene- induced tumorigenesis Nature. 369: 414-418. PMID 7910953 DOI: 10.1038/369414a0  0.44
1994 Naik P, Christofori G, Hanahan D. Insulin-like growth factor II is focally up-regulated and functionally involved as a second signal for oncogene-induced tumorigenesis Cold Spring Harbor Symposia On Quantitative Biology. 59: 459-470. PMID 7587100  0.44
1994 Yoshida T, Hanahan D. Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans American Journal of Pathology. 145: 671-684. PMID 7521578  0.44
1994 Arbeit JM, Münger K, Howley PM, Hanahan D. Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice Journal of Virology. 68: 4358-4368. PMID 7515971  0.44
1994 Ma YH, Landis C, Tchao N, Wang J, Rodd G, Hanahan D, Bourne HR, Grodsky GM. Constitutively active stimulatory G-protein alpha s in beta-cells of transgenic mice causes counterregulation of the increased adenosine 3',5'-monophosphate and insulin secretion. Endocrinology. 134: 42-7. PMID 7506212 DOI: 10.1210/endo.134.1.7506212  0.44
1993 Shing Y, Christofori G, Hanahan D, Ono Y, Sasada R, Igarashi K, Folkman J. Betacellulin: A mitogen from pancreatic β cell tumors Science. 259: 1604-1607. PMID 8456283  0.44
1993 Radvanyi F, Christgau S, Baekkeskov S, Jolicoeur C, Hanahan D. Pancreatic β cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: A potentially general technique for isolating physiologically representative cell lines Molecular and Cellular Biology. 13: 4223-4232. PMID 8391634  0.44
1993 Arbeit JM, Munger K, Howley PM, Hanahan D. Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs American Journal of Pathology. 142: 1187-1197. PMID 8386443  0.44
1993 Hutton JC, Christofori G, Chi WY, Edman U, Guest PC, Hanahan D, Kelly RB. Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue. Molecular Endocrinology (Baltimore, Md.). 7: 1151-60. PMID 8247017 DOI: 10.1210/mend.7.9.8247017  0.44
1993 Teitelman G, Alpert S, Polak JM, Martinez A, Hanahan D. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide Development. 118: 1031-1039. PMID 7903631  0.44
1992 Tal M, Thorens B, Surana M, Fleischer N, Lodish HF, Hanahan D, Efrat S. Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice. Molecular and Cellular Biology. 12: 422-32. PMID 1729614  0.44
1992 Bossy-Wetzel E, Bravo R, Hanahan D. Transcription factors JunB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development Genes and Development. 6: 2340-2351. PMID 1459456  0.44
1991 Hanahan D, Jessee J, Bloom FR. [4] Plasmid transformation of Escherichia coli and other bacteria Methods in Enzymology. 204: 63-114. PMID 1943786 DOI: 10.1016/0076-6879(91)04006-A  0.44
1991 Hicks BA, Stein R, Efrat S, Grant S, Hanahan D, Demetriou AA. Transplantation of beta cells from transgenic mice into nude athymic diabetic rats restores glucose regulation. Diabetes Research and Clinical Practice. 14: 157-64. PMID 1778108 DOI: 10.1016/0168-8227(91)90016-7  0.44
1991 Folkman J, Hanahan D. Switch to the angiogenic phenotype during tumorigenesis Princess Takamatsu Symposia. 22: 339-347. PMID 1726933  0.44
1991 Kandel J, Bossy-Wetzel E, Radvanyi F, Klagsbrun M, Folkman J, Hanahan D. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma Cell. 66: 1095-1104. PMID 1717155  0.44
1991 Grant SG, Seidman I, Hanahan D, Bautch VL. Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice. Cancer Research. 51: 4917-23. PMID 1654206  0.44
1990 Hanahan D. Transgenic mouse models of selftolerance and autoreactivity by the immune system Annual Review of Cell Biology. 6: 493-537. PMID 2275821  0.44
1990 Efrat S, Fleischer N, Hanahan D. Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic β cells Molecular and Cellular Biology. 10: 1779-1783. PMID 2181284  0.44
1990 Grant SG, Jessee J, Bloom FR, Hanahan D. Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants. Proceedings of the National Academy of Sciences of the United States of America. 87: 4645-9. PMID 2162051 DOI: 10.1073/pnas.87.12.4645  0.44
1990 Powers AC, Efrat S, Mojsov S, Spector D, Habener JF, Hanahan D. Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor. Diabetes. 39: 406-14. PMID 2156740  0.44
1990 Skowronski J, Jolicoeur C, Alpert S, Hanahan D. Determinants of the B-cell response against a transgenic autoantigen Proceedings of the National Academy of Sciences of the United States of America. 87: 7492-7496.  0.44
1990 Skowronski J, Jolicoeur C, Alpert S, Hanahan D. Determinants of the B-cell response against a transgenic autoantigen Proceedings of the National Academy of Sciences of the United States of America. 87: 7492-7496.  0.44
1989 Hanahan D. Transgenic mice as probes into complex systems Science. 246: 1265-1275. PMID 2686032  0.44
1989 Hanahan D, Wetzel E, Skowronski J, Sippola-Thiele M, Lindgren V, Howley P. Tumorigenic latency and separable stages during fibrosarcoma development in transgenic mice carrying papillomavirus genomes Princess Takamatsu Symposia. 20: 289-296. PMID 2562186  0.44
1989 Hanahan D, Jolicoeur C, Alpert S, Skowronski J. Alternative self or nonself recognition of an antigen expressed in a rare cell type in transgenic mice: Implications for self-tolerance and autoimmunity Cold Spring Harbor Symposia On Quantitative Biology. 54: 821-835. PMID 2561806  0.44
1989 Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia Nature. 339: 58-61. PMID 2469964  0.44
1989 Jolicoeur C, Skowronsi J, Alpert S, Efrat S, Grant S, Hanahan D. Differential patterns of expression and self-recognition of a hybrid insulin antigen gene in transgenic mice Genes and Gene Products in the Development of Diabetes Mellitus: Proceedings of the 3rd Nordisk Insulin Symposium 'Genes Ane Gene Products in the Development of Diabetes Mellitus'. Ics866. 113-126.  0.44
Show low-probability matches.