| Year |
Citation |
Score |
| 2024 |
Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, ... ... Baldwin AS, et al. Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma. Molecular Cell. PMID 38211588 DOI: 10.1016/j.molcel.2023.12.010 |
0.311 |
|
| 2023 |
Castillo Cabrera J, Dang H, Graves A, Zhang Z, Torres-Castillo J, Li K, King Z, Liu P, Aubé J, Bear JE, Damania B, Hagan RS, Baldwin AS. AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms. Cell Chemical Biology. PMID 37939709 DOI: 10.1016/j.chembiol.2023.10.008 |
0.35 |
|
| 2023 |
Dardis GJ, Wang J, Simon JM, Wang GG, Baldwin AS. An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer. Iscience. 26: 107115. PMID 37416481 DOI: 10.1016/j.isci.2023.107115 |
0.432 |
|
| 2022 |
Xie H, Zhou J, Liu X, Xu Y, Hepperla AJ, Simon JM, Wang T, Yao H, Liao C, Baldwin AS, Gong K, Zhang Q. USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119854119. PMID 36037364 DOI: 10.1073/pnas.2119854119 |
0.304 |
|
| 2022 |
Schrank TP, Prince AC, Sathe T, Wang X, Liu X, Alzhanov DT, Burtness B, Baldwin AS, Yarbrough WG, Issaeva N. NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer. Oncotarget. 13: 707-722. PMID 35634245 DOI: 10.18632/oncotarget.28232 |
0.378 |
|
| 2022 |
Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, ... ... Baldwin AS, et al. Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses. Nature Cell Biology. PMID 35256775 DOI: 10.1038/s41556-022-00853-8 |
0.344 |
|
| 2020 |
Tew BY, Durand JK, Bryant KL, Hayes TK, Peng S, Tran NL, Gooden GC, Buckley DN, Der CJ, Baldwin AS, Salhia B. Genome-wide DNA methylation analysis of KRAS mutant cell lines. Scientific Reports. 10: 10149. PMID 32576853 DOI: 10.1038/S41598-020-66797-X |
0.331 |
|
| 2020 |
Hong K, Hu L, Liu X, Simon JM, Ptacek TS, Zheng X, Liao C, Baldwin AS, Zhang Q. USP37 promotes deubiquitination of HIF2α in kidney cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 32461361 DOI: 10.1073/Pnas.2002567117 |
0.386 |
|
| 2020 |
Liu X, Simon JM, Xie H, Hu L, Wang J, Zurlo G, Fan C, Ptacek TS, Herring L, Tan X, Li M, Baldwin AS, Kim WY, Wu T, Kirschner MW, et al. Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss. Molecular Cell. PMID 32023483 DOI: 10.1016/J.Molcel.2020.01.009 |
0.41 |
|
| 2019 |
Tegowski M, Fan C, Baldwin AS. Selective Effects of Thioridazine on Self-Renewal of Basal-Like Breast Cancer Cells. Scientific Reports. 9: 18695. PMID 31822725 DOI: 10.1038/S41598-019-55145-3 |
0.331 |
|
| 2019 |
Hu L, Xie H, Liu X, Potjewyd F, James LI, Wilkerson EM, Herring LE, Xie L, Chen X, Cabrera JC, Hong K, Liao C, Tan X, Baldwin AS, Gong K, et al. TBK1 is a Synthetic Lethal Target in Cancer with VHL Loss. Cancer Discovery. PMID 31810986 DOI: 10.1158/2159-8290.Cd-19-0837 |
0.433 |
|
| 2019 |
Fan Q, An Z, Wong RA, Luo X, Lu E, Baldwin A, Mayekar MK, Haderk F, Shokat KM, Bivona TG, Weiss WA. Betacellulin drives therapy-resistance in glioblastoma. Neuro-Oncology. PMID 31678994 DOI: 10.1093/Neuonc/Noz206 |
0.34 |
|
| 2019 |
Antonia RJ, Castillo J, Herring LE, Serafin DS, Liu P, Graves LM, Baldwin AS, Hagan RS. TBK1 Limits mTORC1 by Promoting Phosphorylation of Raptor Ser877. Scientific Reports. 9: 13470. PMID 31530866 DOI: 10.1038/S41598-019-49707-8 |
0.473 |
|
| 2019 |
Carneiro-Lobo TC, Scalabrini LC, Magalhães LDS, Cardeal LB, Rodrigues FS, Dos Santos EO, Baldwin AS, Levantini E, Giordano RJ, Bassères DS. IKKβ targeting reduces KRAS-induced lung cancer angiogenesis in vitro and in vivo: A potential anti-angiogenic therapeutic target. Lung Cancer (Amsterdam, Netherlands). 130: 169-178. PMID 30885340 DOI: 10.1016/J.Lungcan.2019.02.027 |
0.424 |
|
| 2018 |
Durand JK, Zhang Q, Baldwin AS. Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer. Cells. 7. PMID 30223576 DOI: 10.3390/Cells7090139 |
0.389 |
|
| 2018 |
Tegowski M, Fan C, Baldwin AS. Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2. The Journal of Biological Chemistry. PMID 30131338 DOI: 10.1074/Jbc.Ra118.003719 |
0.396 |
|
| 2018 |
Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, Liu XD, Jonasch E, Xie L, Chen X, Yao X, Teh BT, Tan P, Zheng X, Li M, ... ... Baldwin AS, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science (New York, N.Y.). 361: 290-295. PMID 30026228 DOI: 10.1126/Science.Aap8411 |
0.423 |
|
| 2018 |
Damrauer JS, Stadler ME, Acharyya S, Baldwin AS, Couch ME, Guttridge DC. Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia. European Journal of Translational Myology. 28: 7590. PMID 29991992 DOI: 10.4081/Ejtm.2018.7590 |
0.402 |
|
| 2018 |
Antonia RJ, Baldwin AS. IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells. Science Signaling. 11. PMID 29991651 DOI: 10.1126/Scisignal.Aan5850 |
0.515 |
|
| 2018 |
Tegowski M, Baldwin A. Noncanonical NF-κB in Cancer. Biomedicines. 6. PMID 29874793 DOI: 10.3390/Biomedicines6020066 |
0.547 |
|
| 2018 |
Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, ... ... Baldwin AS, et al. Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nature Communications. 9: 1988. PMID 29777108 DOI: 10.1038/S41467-018-04355-W |
0.363 |
|
| 2018 |
Carneiro-Lobo TC, Santos EOd, Scalabrini LC, Cardeal LB, Baldwin AS, Giordano RJ, Basseres DS. Abstract B09: Exploring IKKβ as an antiangiogenic therapeutic target in KRAS-induced lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-B09 |
0.443 |
|
| 2017 |
Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Science Signaling. 10. PMID 28223411 DOI: 10.1126/Scisignal.Aah4674 |
0.51 |
|
| 2017 |
Durand JK, Baldwin AS. Targeting IKK and NF-κB for Therapy. Advances in Protein Chemistry and Structural Biology. 107: 77-115. PMID 28215229 DOI: 10.1016/bs.apcsb.2016.11.006 |
0.493 |
|
| 2017 |
Hsia HC, Hutti JE, Baldwin AS. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity. The Journal of Biological Chemistry. PMID 28188292 DOI: 10.1074/Jbc.M116.771964 |
0.428 |
|
| 2017 |
Fowler KA, Jania CM, Tilley SL, Panoskaltsis-Mortari A, Baldwin AS, Serody JS, Coghill JM. Targeting the Canonical NF-κB Pathway with a High Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 28161607 DOI: 10.1016/J.Bbmt.2017.01.083 |
0.379 |
|
| 2017 |
Conard SE, Ebbs A, Baldwin AS. Abstract 2877: IKK-mediated signaling controls prostate tumor initiating cells Cancer Research. 77: 2877-2877. DOI: 10.1158/1538-7445.Am2017-2877 |
0.377 |
|
| 2016 |
Hsia HC, Stopford CM, Zhang Z, Damania B, Baldwin AS. Signal transducer and activator of transcription 3 (Stat3) regulates host defense and protects mice against herpes simplex virus-1 (HSV-1) infection. Journal of Leukocyte Biology. PMID 27965384 DOI: 10.1189/Jlb.4A1016-199Rr |
0.375 |
|
| 2016 |
Lawrence CL, Baldwin AS. Non-Canonical EZH2 Transcriptionally Activates RelB in Triple Negative Breast Cancer. Plos One. 11: e0165005. PMID 27764181 DOI: 10.1371/Journal.Pone.0165005 |
0.449 |
|
| 2016 |
Rinkenbaugh AL, Cogswell PC, Calamini B, Dunn DE, Persson AI, Weiss WA, Lo DC, Baldwin AS. IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance. Oncotarget. PMID 27732951 DOI: 10.18632/Oncotarget.12507 |
0.514 |
|
| 2016 |
Rinkenbaugh AL, Baldwin AS. The NF-κB Pathway and Cancer Stem Cells. Cells. 5. PMID 27058560 DOI: 10.3390/Cells5020016 |
0.558 |
|
| 2016 |
Dan HC, Antonia RJ, Baldwin AS. PI3K/Akt promotes feedforward mTORC2 activation through IKKα. Oncotarget. PMID 27027448 DOI: 10.18632/Oncotarget.8383 |
0.527 |
|
| 2016 |
Bagó JR, Alfonso-Pecchio A, Okolie O, Dumitru R, Rinkenbaugh A, Baldwin AS, Miller CR, Magness ST, Hingtgen SD. Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma. Nature Communications. 7: 10593. PMID 26830441 DOI: 10.1038/Ncomms10593 |
0.336 |
|
| 2016 |
Tegowski M, Santos C, Baldwin A. Abstract 3316: The effects of dopamine receptor 2 on breast cancer tumor initiating cells Cancer Research. 76: 3316-3316. DOI: 10.1158/1538-7445.Am2016-3316 |
0.438 |
|
| 2015 |
Zhang J, Li L, Baldwin AS, Friedman AD, Paz-Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. Plos One. 10: e0130441. PMID 26102347 DOI: 10.1371/Journal.Pone.0130441 |
0.398 |
|
| 2015 |
Bassères DS, Baldwin AS. Using RNA interference in lung cancer cells to target the IKK-NF-κB pathway. Methods in Molecular Biology (Clifton, N.J.). 1280: 447-58. PMID 25736766 DOI: 10.1007/978-1-4939-2422-6_27 |
0.499 |
|
| 2015 |
Rinkenbaugh AL, Cogswell PC, Baldwin AS. Abstract 1515: Inhibition of the IKK/NF-κB pathway impairs glioma stem cell function Cancer Research. 75: 1515-1515. DOI: 10.1158/1538-7445.Am2015-1515 |
0.554 |
|
| 2015 |
Lobo TC, Magalhães L, Cardeal L, Giordano R, Baldwin A, Bassères D. Abstract 1379: IKKβ is a potential anti-angiogenic therapeutic target in KRAS-induced lung cancer Cancer Research. 75: 1379-1379. DOI: 10.1158/1538-7445.Am2015-1379 |
0.476 |
|
| 2015 |
Durand J, Baldwin A. Abstract 1073: KRAS-mediated epigenetic reprogramming upregulates RELB-dependent CXCR2 expression to promote transformation Cancer Research. 75: 1073-1073. DOI: 10.1158/1538-7445.Am2015-1073 |
0.519 |
|
| 2014 |
Dan HC, Ebbs A, Pasparakis M, Van Dyke T, Basseres DS, Baldwin AS. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα). The Journal of Biological Chemistry. 289: 25227-40. PMID 24990947 DOI: 10.1074/Jbc.M114.554881 |
0.494 |
|
| 2014 |
Bassères DS, Ebbs A, Cogswell PC, Baldwin AS. IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity. Genes & Cancer. 5: 41-55. PMID 24955217 DOI: 10.18632/Genesandcancer.5 |
0.477 |
|
| 2014 |
Bradford JW, Baldwin AS. IKK/nuclear factor-kappaB and oncogenesis: roles in tumor-initiating cells and in the tumor microenvironment. Advances in Cancer Research. 121: 125-45. PMID 24889530 DOI: 10.1016/B978-0-12-800249-0.00003-2 |
0.53 |
|
| 2014 |
Habineza Ndikuyeze G, Gaurnier-Hausser A, Patel R, Baldwin AS, May MJ, Flood P, Krick E, Propert KJ, Mason NJ. A phase I clinical trial of systemically delivered NEMO binding domain peptide in dogs with spontaneous activated B-cell like diffuse large B-cell lymphoma. Plos One. 9: e95404. PMID 24798348 DOI: 10.1371/Journal.Pone.0095404 |
0.428 |
|
| 2014 |
Fulton LM, Taylor NA, Coghill JM, West ML, Föger N, Bear JE, Baldwin AS, Panoskaltsis-Mortari A, Serody JS. Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease. European Journal of Immunology. 44: 1662-71. PMID 24752751 DOI: 10.1002/Eji.201344155 |
0.322 |
|
| 2014 |
Kegelman TP, Das SK, Hu B, Bacolod MD, Fuller CE, Menezes ME, Emdad L, Dasgupta S, Baldwin AS, Bruce JN, Dent P, Pellecchia M, Sarkar D, Fisher PB. MDA-9/syntenin is a key regulator of glioma pathogenesis. Neuro-Oncology. 16: 50-61. PMID 24305713 DOI: 10.1093/Neuonc/Not157 |
0.332 |
|
| 2014 |
Kendellen MF, Bradford JW, Lawrence CL, Clark KS, Baldwin AS. Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells. Oncogene. 33: 1297-305. PMID 23474754 DOI: 10.1038/Onc.2013.64 |
0.499 |
|
| 2014 |
Zhang J, Li L, Baldwin AS, Friedman AD, Paz-Priel I. Loss of IKKβ Increases the Number and Self-Renewal Capacity of Hematopoietic Stem Cells Blood. 124: 4345-4345. DOI: 10.1182/Blood.V124.21.4345.4345 |
0.317 |
|
| 2014 |
Rinkenbaugh AL, Cogswell PC, Baldwin AS. Abstract 1946: Inhibition of IKK/NF-κB impairs glioma stem cell function Cancer Research. 74: 1946-1946. DOI: 10.1158/1538-7445.Am2014-1946 |
0.553 |
|
| 2014 |
Weiss W, Fan Q, Baldwin A, Wong R, Shokat K. ET-63 * TARGETING THE EGFR-STAT-NF- B AXIS IN GLIOBLASTOMA Neuro-Oncology. 16: v93-v93. DOI: 10.1093/Neuonc/Nou255.60 |
0.501 |
|
| 2013 |
Wu C, Haynes EM, Asokan SB, Simon JM, Sharpless NE, Baldwin AS, Davis IJ, Johnson GL, Bear JE. Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signaling. The Journal of Cell Biology. 203: 907-16. PMID 24344184 DOI: 10.1083/Jcb.201306032 |
0.443 |
|
| 2013 |
Cooper MJ, Cox NJ, Zimmerman EI, Dewar BJ, Duncan JS, Whittle MC, Nguyen TA, Jones LS, Ghose Roy S, Smalley DM, Kuan PF, Richards KL, Christopherson RI, Jin J, Frye SV, ... ... Baldwin AS, et al. Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia. Plos One. 8: e66755. PMID 23826126 DOI: 10.1371/Journal.Pone.0066755 |
0.419 |
|
| 2013 |
Xu D, Cobb MG, Gavilano L, Witherspoon SM, Williams D, White CD, Taverna P, Bednarski BK, Kim HJ, Baldwin AS, Baines AT. Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine. Cancer Biology & Therapy. 14: 492-501. PMID 23760491 DOI: 10.4161/Cbt.24343 |
0.425 |
|
| 2013 |
Stein SJ, Baldwin AS. Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function. Blood. 121: 5015-24. PMID 23670180 DOI: 10.1182/Blood-2013-02-486142 |
0.639 |
|
| 2013 |
Bang D, Wilson W, Ryan M, Yeh JJ, Baldwin AS. GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB. Cancer Discovery. 3: 690-703. PMID 23547054 DOI: 10.1158/2159-8290.Cd-12-0541 |
0.793 |
|
| 2013 |
Kegelman TP, Das SK, Hu B, Menezes M, Emdad L, Dasgupta S, Baldwin AS, Bruce JN, Dent P, Pellecchia M, Sarkar D, Fisher PB. Abstract B85: MDA-9/syntenin is a key regulator of glioma pathogenesis Cancer Research. 73: 2618-2618. DOI: 10.1158/1538-7445.Tim2013-B85 |
0.405 |
|
| 2013 |
Durand J, Baldwin A. Abstract B24: Ras-mediated epigenetic reprogramming: NF-κB-dependent and independent effects Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B24 |
0.471 |
|
| 2012 |
Zhao YG, Wang Y, Guo Z, Gu AD, Dan HC, Baldwin AS, Hao W, Wan YY. Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway. Journal of Immunology (Baltimore, Md. : 1950). 189: 4417-25. PMID 22993204 DOI: 10.4049/Jimmunol.1200919 |
0.385 |
|
| 2012 |
Allen JL, Fore MS, Wooten J, Roehrs PA, Bhuiya NS, Hoffert T, Sharf A, Deal AM, Armistead P, Coghill J, Gabriel DA, Irons R, Essenmacher A, Shea TC, Richards K, ... ... Baldwin AS, et al. B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways. Blood. 120: 2529-36. PMID 22896003 DOI: 10.1182/Blood-2012-06-438911 |
0.384 |
|
| 2012 |
Hutti JE, Porter MA, Cheely AW, Cantley LC, Wang X, Kireev D, Baldwin AS, Janzen WP. Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε. Plos One. 7: e41494. PMID 22859992 DOI: 10.1371/Journal.Pone.0041494 |
0.331 |
|
| 2012 |
Hutti JE, Pfefferle AD, Russell SC, Sircar M, Perou CM, Baldwin AS. Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation. Cancer Research. 72: 3260-9. PMID 22552288 DOI: 10.1158/0008-5472.Can-11-4141 |
0.591 |
|
| 2012 |
Baldwin AS. Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer. Immunological Reviews. 246: 327-45. PMID 22435564 DOI: 10.1111/J.1600-065X.2012.01095.X |
0.574 |
|
| 2012 |
Santhekadur PK, Das SK, Gredler R, Chen D, Srivastava J, Robertson C, Baldwin AS, Fisher PB, Sarkar D. Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221. The Journal of Biological Chemistry. 287: 13952-8. PMID 22396537 DOI: 10.1074/Jbc.M111.321646 |
0.45 |
|
| 2012 |
Comb WC, Hutti JE, Cogswell P, Cantley LC, Baldwin AS. p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation. Molecular Cell. 45: 719-30. PMID 22342344 DOI: 10.1016/J.Molcel.2012.01.010 |
0.806 |
|
| 2012 |
Awwad Y, Geng T, Baldwin AS, Lu C. Observing single cell NF-κB dynamics under stimulant concentration gradient. Analytical Chemistry. 84: 1224-8. PMID 22263650 DOI: 10.1021/Ac203209T |
0.367 |
|
| 2012 |
Dan H, Baldwin AS. Abstract B34: IKKalpha regulation of mTORC1 and modulation of prostate tumorigenesis through phosphorylation of mTOR Cancer Research. 72: B34-B34. DOI: 10.1158/1538-7445.Prca2012-B34 |
0.5 |
|
| 2012 |
Hutti J, Pfefferle A, Perou C, Baldwin A. Abstract 988: Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation Cancer Research. 72: 988-988. DOI: 10.1158/1538-7445.Am2012-988 |
0.507 |
|
| 2012 |
Basseres DS, Ebbs A, Cogswell PC, Levantini E, Baldwin AS. Abstract 903: The IKKα kinase is a potential therapeutic target in K-Ras-induced lung cancer Cancer Research. 72: 903-903. DOI: 10.1158/1538-7445.Am2012-903 |
0.343 |
|
| 2012 |
Sweeting RS, Kim HJ, Baldwin AS. Abstract 2225: GSK3β plays a significant role in Ras driven tumors potentially through an upstream effect on AKT Cancer Research. 72: 2225-2225. DOI: 10.1158/1538-7445.Am2012-2225 |
0.429 |
|
| 2012 |
Sweeting R, Bang D, Yeh J, Baldwin A, Kim H. The Dominant Role of Glycogen Synthase Kinase-3a in the Growth of Human Pancreatic Cancers Journal of Surgical Research. 172: 341. DOI: 10.1016/j.jss.2011.11.706 |
0.565 |
|
| 2012 |
Allen J, Wooten J, Fore M, Bhuiya N, Armistead P, Coghill J, Gabriel D, Roehrs P, Sharf A, Irons R, Hoffert T, Richards K, Shea T, Baldwin A, Serody J, et al. B Cells from Patients with Chronic GVHD Signal Via the Akt-Driven Survival and Metabolic Fitness Pathway Biology of Blood and Marrow Transplantation. 18: S207-S208. DOI: 10.1016/J.Bbmt.2011.12.017 |
0.348 |
|
| 2011 |
Tanaka K, Babic I, Nathanson D, Akhavan D, Guo D, Gini B, Dang J, Zhu S, Yang H, De Jesus J, Amzajerdi AN, Zhang Y, Dibble CC, Dan H, Rinkenbaugh A, ... ... Baldwin AS, et al. Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance. Cancer Discovery. 1: 524-38. PMID 22145100 DOI: 10.1158/2159-8290.Cd-11-0124 |
0.527 |
|
| 2011 |
Dooher JE, Paz-Priel I, Houng S, Baldwin AS, Friedman AD. C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction. Molecular Cancer Research : McR. 9: 1395-405. PMID 21813505 DOI: 10.1158/1541-7786.Mcr-11-0072 |
0.38 |
|
| 2011 |
Stein SJ, Baldwin AS. NF-κB suppresses ROS levels in BCR-ABL(+) cells to prevent activation of JNK and cell death. Oncogene. 30: 4557-66. PMID 21625221 DOI: 10.1038/Onc.2011.156 |
0.738 |
|
| 2011 |
Gaurnier-Hausser A, Patel R, Baldwin AS, May MJ, Mason NJ. NEMO-binding domain peptide inhibits constitutive NF-κB activity and reduces tumor burden in a canine model of relapsed, refractory diffuse large B-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4661-71. PMID 21610150 DOI: 10.1158/1078-0432.Ccr-10-3310 |
0.527 |
|
| 2011 |
Wysong A, Couch M, Shadfar S, Li L, Li L, Rodriguez JE, Asher S, Yin X, Gore M, Baldwin A, Patterson C, Willis MS. NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo. The American Journal of Pathology. 178: 1059-68. PMID 21356358 DOI: 10.1016/J.Ajpath.2010.12.009 |
0.458 |
|
| 2011 |
Rinkenbaugh AL, Baldwin AS. Monoallelic deletion of NFKBIA in glioblastoma: when less is more. Cancer Cell. 19: 163-5. PMID 21316598 DOI: 10.1016/J.Ccr.2011.01.045 |
0.434 |
|
| 2011 |
Peterson JM, Kline W, Canan BD, Ricca DJ, Kaspar B, Delfín DA, DiRienzo K, Clemens PR, Robbins PD, Baldwin AS, Flood P, Kaumaya P, Freitas M, Kornegay JN, Mendell JR, et al. Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy. Molecular Medicine (Cambridge, Mass.). 17: 508-15. PMID 21267511 DOI: 10.2119/Molmed.2010.00263 |
0.329 |
|
| 2011 |
Comb WC, Cogswell P, Sitcheran R, Baldwin AS. IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene. 30: 1727-32. PMID 21151171 DOI: 10.1038/Onc.2010.553 |
0.825 |
|
| 2011 |
O'Neil BH, Funkhouser WK, Calvo BF, Meyers MO, Kim HJ, Goldberg RM, Bernard SA, Caskey L, Deal AM, Wright F, Baldwin AS, Tepper JE. Nuclear factor κ-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. International Journal of Radiation Oncology, Biology, Physics. 80: 705-11. PMID 20630669 DOI: 10.1016/J.Ijrobp.2010.02.063 |
0.493 |
|
| 2011 |
Wysong A, Asher SA, Yin X, Gore MR, Weinstein L, Guttridge DC, Baldwin AS, Couch ME, Willis MS. Selective inhibition of NF-kappa-B with NBD peptide reduces tumor- induced wasting in a murine model of cancer cachexia in vivo Journal of Cancer Science and Therapy. 3: 022-029. DOI: 10.4172/1948-5956.1000052 |
0.434 |
|
| 2011 |
Bang D, Wilson W, Yeh JJ, Baldwin AS. Abstract 2892: Glycogen synthase kinase-3α regulates cell proliferation in pancreatic cancer cells by regulating constitutive TAK1 and NF-κB signaling Cancer Research. 71: 2892-2892. DOI: 10.1158/1538-7445.Am2011-2892 |
0.74 |
|
| 2011 |
Xu D, Gavilano L, Witherspoon SM, Bednarski B, Kim H, Baldwin AS, Baines AT. Abstract 256: Downregulation of Pim-3 kinase inhibits cell growth and chemosensitizes pancreatic cancer cells to gemcitabine Cancer Research. 71: 256-256. DOI: 10.1158/1538-7445.Am2011-256 |
0.417 |
|
| 2010 |
Balasubramani A, Shibata Y, Crawford GE, Baldwin AS, Hatton RD, Weaver CT. Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. Immunity. 33: 35-47. PMID 20643337 DOI: 10.1016/J.Immuni.2010.07.004 |
0.38 |
|
| 2010 |
Puvvada SD, Funkhouser WK, Greene K, Deal A, Chu H, Baldwin AS, Tepper JE, O'Neil BH. NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. Oncology. 78: 181-8. PMID 20414006 DOI: 10.1159/000313697 |
0.526 |
|
| 2010 |
Bassères DS, Ebbs A, Levantini E, Baldwin AS. Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis. Cancer Research. 70: 3537-46. PMID 20406971 DOI: 10.1158/0008-5472.Can-09-4290 |
0.412 |
|
| 2010 |
Adli M, Merkhofer E, Cogswell P, Baldwin AS. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway. Plos One. 5: e9428. PMID 20195534 DOI: 10.1371/Journal.Pone.0009428 |
0.817 |
|
| 2010 |
Merkhofer EC, Cogswell P, Baldwin AS. Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene. 29: 1238-48. PMID 19946332 DOI: 10.1038/Onc.2009.410 |
0.822 |
|
| 2010 |
Dooher JE, Paz-Priel I, Houng S, Baldwin AS, Friedman AD. C/EBPα, C/EBPα Oncoproteins, or C/EBPβ Preferentially Bind NF-κB p50 Compared with p65 Via Conserved Residues In the C/EBP Basic Region Blood. 116: 708-708. DOI: 10.1182/Blood.V116.21.708.708 |
0.419 |
|
| 2010 |
Wooten J, Nazmim BS, Richards K, Sharf A, Antin JH, Soiffer RJ, Ritz J, Shea TC, Serody J, Baldwin AS, Sarantopoulos S. B Cells Are Primed for Survival by BAFF-Driven Bim Degradation In Chronic Graft Versus Host Disease (cGVHD) Patients Blood. 116: 216-216. DOI: 10.1182/Blood.V116.21.216.216 |
0.387 |
|
| 2010 |
Xu D, Bednarski B, Kim H, Baldwin A, Baines AT. Abstract 3104: The role of Pim-3 kinase in NF-κB signaling and transformation of pancreatic cancer Cancer Research. 70: 3104-3104. DOI: 10.1158/1538-7445.Am10-3104 |
0.465 |
|
| 2009 |
Bednarski BK, Baldwin AS, Kim HJ. Addressing reported pro-apoptotic functions of NF-kappaB: targeted inhibition of canonical NF-kappaB enhances the apoptotic effects of doxorubicin. Plos One. 4: e6992. PMID 19746155 DOI: 10.1371/Journal.Pone.0006992 |
0.569 |
|
| 2009 |
Raetzsch CF, Brooks NL, Alderman JM, Moore KS, Hosick PA, Klebanov S, Akira S, Bear JE, Baldwin AS, Mackman N, Combs TP. Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway. Hepatology (Baltimore, Md.). 50: 592-600. PMID 19492426 DOI: 10.1002/Hep.22999 |
0.356 |
|
| 2009 |
O'Shaughnessy MJ, Vogtenhuber C, Sun K, Sitcheran R, Baldwin AS, Murphy WJ, Dang L, Jaffee B, Palmer E, Serody JS, Blazar BR. Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 452-62. PMID 19260829 DOI: 10.1111/J.1600-6143.2008.02533.X |
0.461 |
|
| 2009 |
Laurenzana A, Petruccelli LA, Pettersson F, Figueroa ME, Melnick A, Baldwin AS, Paoletti F, Miller WH. Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells. Cancer Research. 69: 55-64. PMID 19117987 DOI: 10.1158/0008-5472.Can-08-0245 |
0.417 |
|
| 2009 |
Bednarski B, Baldwin A, Kim H. 170. NF-κB-Mediated Expression of CIAP2 is Critical to Chemoresistance in Sarcomas Journal of Surgical Research. 151: 250-251. DOI: 10.1016/j.jss.2008.11.207 |
0.411 |
|
| 2009 |
Bednarski BK, Baldwin AS, Kim HJ. NF-kappaB and chemoresistance in sarcomas: The importance of IKKalpha in canonical signaling Journal of the American College of Surgeons. 209: S121. DOI: 10.1016/J.Jamcollsurg.2009.06.300 |
0.48 |
|
| 2008 |
Puvvada SD, O'Neil BH, Deal A, Greene K, Chu H, Baldwin AS, Funkhouser WK. Prognostic implication of NF-κB and BCL3 activation in metastatic colorectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 11090. PMID 27947682 DOI: 10.1200/Jco.2008.26.15_Suppl.11090 |
0.487 |
|
| 2008 |
Moss NC, Tang RH, Willis M, Stansfield WE, Baldwin AS, Selzman CH. Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection. The Journal of Thoracic and Cardiovascular Surgery. 136: 1274-9. PMID 19026814 DOI: 10.1016/J.Jtcvs.2008.07.041 |
0.372 |
|
| 2008 |
Wilson W, Baldwin AS. Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer. Cancer Research. 68: 8156-63. PMID 18829575 DOI: 10.1158/0008-5472.Can-08-1061 |
0.711 |
|
| 2008 |
Goetz CA, Baldwin AS. NF-kappaB pathways in the immune system: control of the germinal center reaction. Immunologic Research. 41: 233-47. PMID 18670738 DOI: 10.1007/S12026-008-8033-1 |
0.51 |
|
| 2008 |
Bednarski BK, Ding X, Coombe K, Baldwin AS, Kim HJ. Active roles for inhibitory kappaB kinases alpha and beta in nuclear factor-kappaB-mediated chemoresistance to doxorubicin. Molecular Cancer Therapeutics. 7: 1827-35. PMID 18644995 DOI: 10.1158/1535-7163.Mct-08-0321 |
0.584 |
|
| 2008 |
Sitcheran R, Comb WC, Cogswell PC, Baldwin AS. Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB. Molecular and Cellular Biology. 28: 5061-70. PMID 18541671 DOI: 10.1128/Mcb.00578-08 |
0.813 |
|
| 2008 |
Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes & Development. 22: 1490-500. PMID 18519641 DOI: 10.1101/Gad.1662308 |
0.585 |
|
| 2008 |
Dan HC, Baldwin AS. Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt. Journal of Immunology (Baltimore, Md. : 1950). 180: 7582-9. PMID 18490760 DOI: 10.4049/Jimmunol.180.11.7582 |
0.522 |
|
| 2008 |
Tang RH, Zheng XL, Callis TE, Stansfield WE, He J, Baldwin AS, Wang DZ, Selzman CH. Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 105: 3362-7. PMID 18296632 DOI: 10.1073/Pnas.0705842105 |
0.561 |
|
| 2008 |
Steinbrecher KA, Harmel-Laws E, Sitcheran R, Baldwin AS. Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation. Journal of Immunology (Baltimore, Md. : 1950). 180: 2588-99. PMID 18250470 DOI: 10.4049/Jimmunol.180.4.2588 |
0.44 |
|
| 2008 |
Duncan EA, Goetz CA, Stein SJ, Mayo KJ, Skaggs BJ, Ziegelbauer K, Sawyers CL, Baldwin AS. IkappaB kinase beta inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells. Molecular Cancer Therapeutics. 7: 391-7. PMID 18245668 DOI: 10.1158/1535-7163.Mct-07-0305 |
0.734 |
|
| 2008 |
Witcher M, Pettersson F, Dupéré-Richer D, Padovani A, Summers-Deluca L, Baldwin AS, Miller WH. Retinoic acid modulates chromatin to potentiate tumor necrosis factor alpha signaling on the DIF2 promoter. Nucleic Acids Research. 36: 435-43. PMID 18039708 DOI: 10.1093/Nar/Gkm1058 |
0.447 |
|
| 2008 |
Stansfield WE, Tang RH, Moss NC, Baldwin AS, Willis MS, Selzman CH. Proteasome inhibition promotes regression of left ventricular hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 294: H645-50. PMID 18032525 DOI: 10.1152/Ajpheart.00196.2007 |
0.41 |
|
| 2007 |
O'Neil BH, Bůzková P, Farrah H, Kashatus D, Sanoff H, Goldberg RM, Baldwin AS, Funkhouser WK. Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology. 72: 97-104. PMID 18025803 DOI: 10.1159/000111116 |
0.435 |
|
| 2007 |
Davé SH, Tilstra JS, Matsuoka K, Li F, Karrasch T, Uno JK, Sepulveda AR, Jobin C, Baldwin AS, Robbins PD, Plevy SE. Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide. Journal of Immunology (Baltimore, Md. : 1950). 179: 7852-9. PMID 18025231 DOI: 10.4049/Jimmunol.179.11.7852 |
0.5 |
|
| 2007 |
Wang J, An H, Mayo MW, Baldwin AS, Yarbrough WG. LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB. Cancer Cell. 12: 239-51. PMID 17785205 DOI: 10.1016/J.Ccr.2007.07.002 |
0.537 |
|
| 2007 |
Dan HC, Adli M, Baldwin AS. Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha. Cancer Research. 67: 6263-9. PMID 17616684 DOI: 10.1158/0008-5472.Can-07-1232 |
0.71 |
|
| 2007 |
Gilbert MR, Carnathan DG, Cogswell PC, Lin L, Baldwin AS, Vilen BJ. Dendritic cells from lupus-prone mice are defective in repressing immunoglobulin secretion. Journal of Immunology (Baltimore, Md. : 1950). 178: 4803-10. PMID 17404261 DOI: 10.4049/Jimmunol.178.8.4803 |
0.316 |
|
| 2007 |
Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, ... Baldwin AS, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/Jci30556 |
0.443 |
|
| 2007 |
Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin AS, Tisch RM. Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells. Blood. 109: 653-60. PMID 17008547 DOI: 10.1182/Blood-2006-04-017368 |
0.513 |
|
| 2007 |
Basseres DS, Baldwin AS. P2-115: A Causal Relationship between Oncogenic K-Ras Expression and NF-kappaB Activation in Lung Cancer Journal of Thoracic Oncology. 2: S536-S537. DOI: 10.1097/01.Jto.0000283579.71817.F9 |
0.404 |
|
| 2007 |
Bednarski BK, Ding X, Baldwin A, Kim HJ. NF-kappaB activation in response to doxorubicin induces cIAP-2 expression leading to chemoresistance in human sarcomas Journal of the American College of Surgeons. 205: S88. DOI: 10.1016/J.Jamcollsurg.2007.06.220 |
0.49 |
|
| 2006 |
Bassères DS, Baldwin AS. Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene. 25: 6817-30. PMID 17072330 DOI: 10.1038/Sj.Onc.1209942 |
0.461 |
|
| 2006 |
Adli M, Baldwin AS. IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation. The Journal of Biological Chemistry. 281: 26976-84. PMID 16840782 DOI: 10.1074/Jbc.M603133200 |
0.773 |
|
| 2006 |
Duncan EA, Anest V, Cogswell P, Baldwin AS. The kinases MSK1 and MSK2 are required for epidermal growth factor-induced, but not tumor necrosis factor-induced, histone H3 Ser10 phosphorylation. The Journal of Biological Chemistry. 281: 12521-5. PMID 16517600 DOI: 10.1074/Jbc.M513333200 |
0.415 |
|
| 2006 |
Karrasch T, Steinbrecher KA, Allard B, Baldwin AS, Jobin C. Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes. Journal of Cellular Physiology. 207: 809-15. PMID 16508963 DOI: 10.1002/Jcp.20626 |
0.495 |
|
| 2006 |
Kim HJ, Hawke N, Baldwin AS. NF-kappaB and IKK as therapeutic targets in cancer. Cell Death and Differentiation. 13: 738-47. PMID 16485028 DOI: 10.1038/Sj.Cdd.4401877 |
0.586 |
|
| 2006 |
Kashatus D, Cogswell P, Baldwin AS. Expression of the Bcl-3 proto-oncogene suppresses p53 activation. Genes & Development. 20: 225-35. PMID 16384933 DOI: 10.1101/Gad.1352206 |
0.433 |
|
| 2005 |
Steinbrecher KA, Wilson W, Cogswell PC, Baldwin AS. Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription. Molecular and Cellular Biology. 25: 8444-55. PMID 16166627 DOI: 10.1128/Mcb.25.19.8444-8455.2005 |
0.661 |
|
| 2005 |
Sitcheran R, Gupta P, Fisher PB, Baldwin AS. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. The Embo Journal. 24: 510-20. PMID 15660126 DOI: 10.1038/Sj.Emboj.7600555 |
0.577 |
|
| 2005 |
O’Neil BH, Farrah H, Kelly H, Baldwin AS, Funkhouser WK. Analysis of NF-kappa B in hepatocellular carcinoma (HCC) reveals frequent activation of p50 and bcl-3 Journal of Clinical Oncology. 23: 9621-9621. DOI: 10.1200/Jco.2005.23.16_Suppl.9621 |
0.327 |
|
| 2004 |
Sarkar D, Lebedeva IV, Emdad L, Kang DC, Baldwin AS, Fisher PB. Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation. Cancer Research. 64: 7473-8. PMID 15492272 DOI: 10.1158/0008-5472.Can-04-1772 |
0.46 |
|
| 2004 |
Hanson JL, Hawke NA, Kashatus D, Baldwin AS. The nuclear factor kappaB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer Research. 64: 7248-55. PMID 15492243 DOI: 10.1158/0008-5472.Can-03-3898 |
0.494 |
|
| 2004 |
Loercher A, Lee TL, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS, Van Waes C. Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Research. 64: 6511-23. PMID 15374962 DOI: 10.1158/0008-5472.Can-04-0852 |
0.524 |
|
| 2004 |
Anest V, Cogswell PC, Baldwin AS. IkappaB kinase alpha and p65/RelA contribute to optimal epidermal growth factor-induced c-fos gene expression independent of IkappaBalpha degradation. The Journal of Biological Chemistry. 279: 31183-9. PMID 15155743 DOI: 10.1074/Jbc.M404380200 |
0.512 |
|
| 2004 |
Kurenova E, Xu LH, Yang X, Baldwin AS, Craven RJ, Hanks SK, Liu ZG, Cance WG. Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Molecular and Cellular Biology. 24: 4361-71. PMID 15121855 DOI: 10.1128/Mcb.24.10.4361-4371.2004 |
0.389 |
|
| 2004 |
Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS, Tisch R. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood. 104: 1100-9. PMID 15113757 DOI: 10.1182/Blood-2003-12-4302 |
0.5 |
|
| 2004 |
Baldwin AS. NF kappa B: biology and pathology--Keystone Symposium. 11-16 January 2004, Snowbird, UT, USA. Idrugs : the Investigational Drugs Journal. 7: 215-6. PMID 15017459 |
0.304 |
|
| 2004 |
O’Shaughnessy MJ, Vogtenhuber C, Serody JS, Sitcheran R, Baldwin AS, Dang L, Jaffee B, Blazar BR. Ex Vivo Blockade of NF-[dappa]B Signaling in Alloreactive T Cells Prevents Murine Graft-Versus-Host Disease (GVHD). Blood. 104: 3058-3058. DOI: 10.1182/Blood.V104.11.3058.3058 |
0.435 |
|
| 2003 |
Baer JT, Du Laney TV, Wyrick PB, McCain AS, Fischer TA, Merricks EP, Baldwin AS, Nichols TC. Nuclear factor-kappaB activation in endothelium by Chlamydia pneumoniae without active infection. The Journal of Infectious Diseases. 188: 1094-7. PMID 14551877 DOI: 10.1086/378564 |
0.492 |
|
| 2003 |
Sitcheran R, Cogswell PC, Baldwin AS. NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes & Development. 17: 2368-73. PMID 14522944 DOI: 10.1101/Gad.1114503 |
0.549 |
|
| 2003 |
Hanson JL, Anest V, Reuther-Madrid J, Baldwin AS. Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathways. The Journal of Biological Chemistry. 278: 34910-7. PMID 12851413 DOI: 10.1074/Jbc.M304189200 |
0.564 |
|
| 2003 |
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature. 423: 659-63. PMID 12789343 DOI: 10.1038/Nature01648 |
0.482 |
|
| 2003 |
Madrid LV, Baldwin AS. Regulation of NF-kappaB by oncoproteins and tumor suppressor proteins. Methods in Molecular Biology (Clifton, N.J.). 223: 523-32. PMID 12777748 DOI: 10.1385/1-59259-329-1:523 |
0.453 |
|
| 2003 |
Weaver KD, Yeyeodu S, Cusack JC, Baldwin AS, Ewend MG. Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas. Journal of Neuro-Oncology. 61: 187-96. PMID 12675310 DOI: 10.1023/A:1022554824129 |
0.507 |
|
| 2003 |
Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS, Tisch R. NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. Journal of Immunology (Baltimore, Md. : 1950). 170: 1770-80. PMID 12574341 DOI: 10.4049/Jimmunol.170.4.1770 |
0.483 |
|
| 2003 |
Cogswell PC, Kashatus DF, Keifer JA, Guttridge DC, Reuther JY, Bristow C, Roy S, Nicholson DW, Baldwin AS. NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B. The Journal of Biological Chemistry. 278: 2963-8. PMID 12433922 DOI: 10.1074/Jbc.M209995200 |
0.456 |
|
| 2003 |
Pye J, Ardeshirpour F, McCain A, Bellinger DA, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin AS, Nichols TC. Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 284: H919-26. PMID 12424098 DOI: 10.1152/Ajpheart.00851.2002 |
0.349 |
|
| 2002 |
Orlowski RZ, Baldwin AS. NF-kappaB as a therapeutic target in cancer. Trends in Molecular Medicine. 8: 385-9. PMID 12127724 DOI: 10.1016/S1471-4914(02)02375-4 |
0.543 |
|
| 2002 |
Carballo M, Conde M, Tejedo J, Gualberto A, Jimenez J, MonteseirÃn J, Santa MarÃa C, Bedoya FJ, Hunt SW, Pintado E, Baldwin AS, Sobrino F. Macrophage inducible nitric oxide synthase gene expression is blocked by a benzothiophene derivative with anti-HIV properties. Molecular Genetics and Metabolism. 75: 360-8. PMID 12051968 DOI: 10.1016/S1096-7192(02)00001-X |
0.338 |
|
| 2002 |
Mayo MW, Madrid LV, Westerheide SD, Jones DR, Yuan XJ, Baldwin AS, Whang YE. PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit. The Journal of Biological Chemistry. 277: 11116-25. PMID 11799112 DOI: 10.1074/Jbc.M108670200 |
0.616 |
|
| 2002 |
Poligone B, Weaver DJ, Sen P, Baldwin AS, Tisch R. Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function. Journal of Immunology (Baltimore, Md. : 1950). 168: 188-96. PMID 11751962 DOI: 10.4049/Jimmunol.168.1.188 |
0.413 |
|
| 2001 |
Nichols TC, Fischer TH, Deliargyris EN, Baldwin AS. Role of nuclear factor-kappa B (NF-kappa B) in inflammation, periodontitis, and atherogenesis. Annals of Periodontology / the American Academy of Periodontology. 6: 20-9. PMID 11887466 DOI: 10.1902/Annals.2001.6.1.20 |
0.51 |
|
| 2001 |
Westerheide SD, Mayo MW, Anest V, Hanson JL, Baldwin AS. The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition. Molecular and Cellular Biology. 21: 8428-36. PMID 11713278 DOI: 10.1128/Mcb.21.24.8428-8436.2001 |
0.451 |
|
| 2001 |
Ashburner BP, Westerheide SD, Baldwin AS. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Molecular and Cellular Biology. 21: 7065-77. PMID 11564889 DOI: 10.1128/Mcb.21.20.7065-7077.2001 |
0.548 |
|
| 2001 |
Poligone B, Baldwin AS. Positive and negative regulation of NF-kappaB by COX-2: roles of different prostaglandins. The Journal of Biological Chemistry. 276: 38658-64. PMID 11509575 DOI: 10.1074/Jbc.M106599200 |
0.555 |
|
| 2001 |
Holmes-McNary MQ, Baldwin AS, Zeisel SH. Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB. The Journal of Biological Chemistry. 276: 41197-204. PMID 11483591 DOI: 10.1074/Jbc.M010936200 |
0.463 |
|
| 2001 |
Weaver DJ, Poligone B, Bui T, Abdel-Motal UM, Baldwin AS, Tisch R. Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase. Journal of Immunology (Baltimore, Md. : 1950). 167: 1461-8. PMID 11466366 DOI: 10.4049/Jimmunol.167.3.1461 |
0.402 |
|
| 2001 |
Mayo MW, Norris JL, Baldwin AS. Ras regulation of NF-kappa B and apoptosis. Methods in Enzymology. 333: 73-87. PMID 11400356 DOI: 10.1016/S0076-6879(01)33046-X |
0.486 |
|
| 2001 |
Russo SM, Tepper JE, Baldwin AS, Liu R, Adams J, Elliott P, Cusack JC. Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB. International Journal of Radiation Oncology, Biology, Physics. 50: 183-93. PMID 11316563 DOI: 10.1016/S0360-3016(01)01446-8 |
0.557 |
|
| 2001 |
Keifer JA, Guttridge DC, Ashburner BP, Baldwin AS. Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity. The Journal of Biological Chemistry. 276: 22382-7. PMID 11297551 DOI: 10.1074/Jbc.M100938200 |
0.552 |
|
| 2001 |
Madrid LV, Mayo MW, Reuther JY, Baldwin AS. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. The Journal of Biological Chemistry. 276: 18934-40. PMID 11259436 DOI: 10.1074/Jbc.M101103200 |
0.552 |
|
| 2001 |
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. The Journal of Clinical Investigation. 107: 241-6. PMID 11160144 DOI: 10.1172/Jci11991 |
0.538 |
|
| 2001 |
Baldwin AS. Series introduction: the transcription factor NF-kappaB and human disease. The Journal of Clinical Investigation. 107: 3-6. PMID 11134170 DOI: 10.1172/Jci11891 |
0.486 |
|
| 2000 |
Jones DR, Broad RM, Madrid LV, Baldwin AS, Mayo MW. Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis. The Annals of Thoracic Surgery. 70: 930-6; discussion 93. PMID 11016336 DOI: 10.1016/S0003-4975(00)01635-0 |
0.52 |
|
| 2000 |
Guttridge DC, Mayo MW, Madrid LV, Wang CY, Baldwin AS. NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. Science (New York, N.Y.). 289: 2363-6. PMID 11009425 DOI: 10.1126/Science.289.5488.2363 |
0.456 |
|
| 2000 |
Wang D, Westerheide SD, Hanson JL, Baldwin AS. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. The Journal of Biological Chemistry. 275: 32592-7. PMID 10938077 DOI: 10.1074/Jbc.M001358200 |
0.568 |
|
| 2000 |
Xu LH, Yang X, Bradham CA, Brenner DA, Baldwin AS, Craven RJ, Cance WG. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. The Journal of Biological Chemistry. 275: 30597-604. PMID 10899173 DOI: 10.1074/Jbc.M910027199 |
0.424 |
|
| 2000 |
Mayo MW, Baldwin AS. The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance. Biochimica Et Biophysica Acta. 1470: M55-62. PMID 10722927 DOI: 10.1016/S0304-419X(00)00002-0 |
0.548 |
|
| 2000 |
Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene. 19: 1123-31. PMID 10713699 DOI: 10.1038/Sj.Onc.1203412 |
0.499 |
|
| 2000 |
Madrid LV, Wang CY, Guttridge DC, Schottelius AJ, Baldwin AS, Mayo MW. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Molecular and Cellular Biology. 20: 1626-38. PMID 10669740 DOI: 10.1128/Mcb.20.5.1626-1638.2000 |
0.572 |
|
| 1999 |
Cusack JC, Liu R, Baldwin AS. NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 2: 271-273. PMID 11504498 DOI: 10.1054/Drup.1999.0094 |
0.584 |
|
| 1999 |
Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. The Journal of Biological Chemistry. 274: 31868-74. PMID 10542212 DOI: 10.1074/Jbc.274.45.31868 |
0.56 |
|
| 1999 |
Wang CY, Guttridge DC, Mayo MW, Baldwin AS. NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Molecular and Cellular Biology. 19: 5923-9. PMID 10454539 DOI: 10.1128/Mcb.19.9.5923 |
0.512 |
|
| 1999 |
Batra RK, Guttridge DC, Brenner DA, Dubinett SM, Baldwin AS, Boucher RC. IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. American Journal of Respiratory Cell and Molecular Biology. 21: 238-45. PMID 10423407 DOI: 10.1165/Ajrcmb.21.2.3470 |
0.538 |
|
| 1999 |
Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Molecular and Cellular Biology. 19: 5785-99. PMID 10409765 DOI: 10.1128/Mcb.19.8.5785 |
0.549 |
|
| 1999 |
Mayo MW, Wang CY, Drouin SS, Madrid LV, Marshall AF, Reed JC, Weissman BE, Baldwin AS. WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene. The Embo Journal. 18: 3990-4003. PMID 10406804 DOI: 10.1093/Emboj/18.14.3990 |
0.41 |
|
| 1999 |
Reuther JY, Baldwin AS. Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB. The Journal of Biological Chemistry. 274: 20664-70. PMID 10400699 DOI: 10.1074/Jbc.274.29.20664 |
0.507 |
|
| 1999 |
Norris JL, Baldwin AS. Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways. The Journal of Biological Chemistry. 274: 13841-6. PMID 10318790 DOI: 10.1074/Jbc.274.20.13841 |
0.521 |
|
| 1999 |
Wang CY, Cusack JC, Liu R, Baldwin AS. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nature Medicine. 5: 412-7. PMID 10202930 DOI: 10.1038/7410 |
0.442 |
|
| 1999 |
Cheshire JL, Williams BR, Baldwin AS. Involvement of double-stranded RNA-activated protein kinase in the synergistic activation of nuclear factor-kappaB by tumor necrosis factor-alpha and gamma-interferon in preneuronal cells. The Journal of Biological Chemistry. 274: 4801-6. PMID 9988719 DOI: 10.1074/Jbc.274.8.4801 |
0.497 |
|
| 1998 |
Miagkov AV, Kovalenko DV, Brown CE, Didsbury JR, Cogswell JP, Stimpson SA, Baldwin AS, Makarov SS. NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proceedings of the National Academy of Sciences of the United States of America. 95: 13859-64. PMID 9811891 DOI: 10.1073/Pnas.95.23.13859 |
0.52 |
|
| 1998 |
Wang D, Baldwin AS. Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529. The Journal of Biological Chemistry. 273: 29411-6. PMID 9792644 DOI: 10.1074/Jbc.273.45.29411 |
0.591 |
|
| 1998 |
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science (New York, N.Y.). 281: 1680-3. PMID 9733516 DOI: 10.1126/Science.281.5383.1680 |
0.52 |
|
| 1998 |
Miller WE, Cheshire JL, Baldwin AS, Raab-Traub N. The NPC derived C15 LMP1 protein confers enhanced activation of NF-kappa B and induction of the EGFR in epithelial cells. Oncogene. 16: 1869-77. PMID 9583684 DOI: 10.1038/Sj.Onc.1201696 |
0.478 |
|
| 1998 |
Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS. A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes & Development. 12: 968-81. PMID 9531535 DOI: 10.1101/Gad.12.7.968 |
0.572 |
|
| 1998 |
Gualberto A, Marquez G, Carballo M, Youngblood GL, Hunt SW, Baldwin AS, Sobrino F. p53 transactivation of the HIV-1 long terminal repeat is blocked by PD 144795, a calcineurin-inhibitor with anti-HIV properties. The Journal of Biological Chemistry. 273: 7088-93. PMID 9507019 DOI: 10.1074/Jbc.273.12.7088 |
0.331 |
|
| 1998 |
Baldwin AS. Role of NF-KB in regulating apoptosis and oncogenesis Free Radical Biology and Medicine. 25: S3. DOI: 10.1016/S0891-5849(98)90010-7 |
0.388 |
|
| 1998 |
Schottelius A, Mayo M, Sartor R, Baldwin A. IL-10 modulates NF-κB activity in human monocytic cell lines by blocking DNA-binding rather than inhibiting nuclear translocation Gastroenterology. 114: A1080. DOI: 10.1016/S0016-5085(98)84393-X |
0.333 |
|
| 1997 |
Mayo MW, Wang CY, Cogswell PC, Rogers-Graham KS, Lowe SW, Der CJ, Baldwin AS. Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras. Science (New York, N.Y.). 278: 1812-5. PMID 9388187 DOI: 10.1126/Science.278.5344.1812 |
0.487 |
|
| 1997 |
Cheshire JL, Baldwin AS. Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation. Molecular and Cellular Biology. 17: 6746-54. PMID 9343439 DOI: 10.1128/Mcb.17.11.6746 |
0.493 |
|
| 1997 |
Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ, Baldwin AS. Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. The Journal of Biological Chemistry. 272: 24113-6. PMID 9305854 DOI: 10.1074/Jbc.272.39.24113 |
0.562 |
|
| 1997 |
Wang D, Mayo MW, Baldwin AS. Basic fibroblast growth factor transcriptional autoregulation requires EGR-1. Oncogene. 14: 2291-9. PMID 9178905 DOI: 10.1038/Sj.Onc.1201069 |
0.387 |
|
| 1997 |
Yurochko AD, Mayo MW, Poma EE, Baldwin AS, Huang ES. Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters. Journal of Virology. 71: 4638-48. PMID 9151857 DOI: 10.1128/Jvi.71.6.4638-4648.1997 |
0.41 |
|
| 1997 |
Cogswell PC, Mayo MW, Baldwin AS. Involvement of Egr-1/RelA synergy in distinguishing T cell activation from tumor necrosis factor-alpha-induced NF-kappa B1 transcription. The Journal of Experimental Medicine. 185: 491-7. PMID 9053449 DOI: 10.1084/Jem.185.3.491 |
0.526 |
|
| 1996 |
Wang CY, Mayo MW, Baldwin AS. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science (New York, N.Y.). 274: 784-7. PMID 8864119 DOI: 10.1126/Science.274.5288.784 |
0.562 |
|
| 1996 |
Baldwin AS. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annual Review of Immunology. 14: 649-83. PMID 8717528 DOI: 10.1146/Annurev.Immunol.14.1.649 |
0.551 |
|
| 1995 |
Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS. Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Molecular and Cellular Biology. 15: 943-53. PMID 7823959 DOI: 10.1128/Mcb.15.2.943 |
0.537 |
|
| 1995 |
Paine E, Scheinman RI, Baldwin AS, Raab-Traub N. Expression of LMP1 in epithelial cells leads to the activation of a select subset of NF-kappa B/Rel family proteins. Journal of Virology. 69: 4572-6. PMID 7769726 DOI: 10.1128/Jvi.69.7.4572-4576.1995 |
0.392 |
|
| 1995 |
Gualberto A, Hixon ML, Finco TS, Perkins ND, Nabel GJ, Baldwin AS. A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat. Molecular and Cellular Biology. 15: 3450-9. PMID 7760842 DOI: 10.1128/Mcb.15.6.3450 |
0.365 |
|
| 1995 |
Toth CR, Hostutler RF, Baldwin AS, Bender TP. Members of the nuclear factor kappa B family transactivate the murine c-myb gene. The Journal of Biological Chemistry. 270: 7661-71. PMID 7706314 DOI: 10.1074/Jbc.270.13.7661 |
0.444 |
|
| 1995 |
Gualberto A, Baldwin AS. p53 and Sp1 interact and cooperate in the tumor necrosis factor-induced transcriptional activation of the HIV-1 long terminal repeat. The Journal of Biological Chemistry. 270: 19680-3. PMID 7649977 DOI: 10.1074/Jbc.270.34.19680 |
0.379 |
|
| 1995 |
Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science (New York, N.Y.). 270: 283-6. PMID 7569975 DOI: 10.1126/Science.270.5234.283 |
0.435 |
|
| 1995 |
Finco TS, Baldwin AS. Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity. 3: 263-72. PMID 7552992 DOI: 10.1016/1074-7613(95)90112-4 |
0.479 |
|
| 1995 |
Paine E, Scheinman RI, Baldwin AS, Raab-Traub N. Expression of LMP1 in epithelial cells leads to the activation of a select subset of NF-kappa B/Rel family proteins. Journal of Virology. 69: 4572-4576. DOI: 10.1128/jvi.69.7.4572-4576.1995 |
0.327 |
|
| 1994 |
Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin AS, Basta PV, Ting JP. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits. Molecular and Cellular Biology. 14: 2926-35. PMID 8164652 DOI: 10.1128/Mcb.14.5.2926 |
0.419 |
|
| 1994 |
Gutsch DE, Holley-Guthrie EA, Zhang Q, Stein B, Blanar MA, Baldwin AS, Kenney SC. The bZIP transactivator of Epstein-Barr virus, BZLF1, functionally and physically interacts with the p65 subunit of NF-kappa B. Molecular and Cellular Biology. 14: 1939-48. PMID 8114725 DOI: 10.1128/Mcb.14.3.1939 |
0.423 |
|
| 1994 |
Finco TS, Beg AA, Baldwin AS. Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 91: 11884-8. PMID 7991551 DOI: 10.1073/Pnas.91.25.11884 |
0.46 |
|
| 1994 |
Ito CY, Kazantsev AG, Baldwin AS. Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha. Nucleic Acids Research. 22: 3787-92. PMID 7937093 DOI: 10.1093/Nar/22.18.3787 |
0.409 |
|
| 1993 |
Beg AA, Finco TS, Nantermet PV, Baldwin AS. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation. Molecular and Cellular Biology. 13: 3301-10. PMID 8497253 DOI: 10.1128/mcb.13.6.3301-3310.1993 |
0.469 |
|
| 1993 |
Ting JP, Baldwin AS. Regulation of MHC gene expression. Current Opinion in Immunology. 5: 8-16. PMID 8452678 DOI: 10.1016/0952-7915(93)90074-3 |
0.367 |
|
| 1993 |
Stein B, Baldwin AS. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B. Molecular and Cellular Biology. 13: 7191-8. PMID 8413306 DOI: 10.1128/mcb.13.11.7191-7198.1993 |
0.442 |
|
| 1993 |
Scheinman RI, Beg AA, Baldwin AS. NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule. Molecular and Cellular Biology. 13: 6089-101. PMID 8413211 DOI: 10.1128/mcb.13.10.6089-6101.1993 |
0.458 |
|
| 1993 |
Kowalik TF, Wing B, Haskill JS, Azizkhan JC, Baldwin AS, Huang ES. Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 90: 1107-11. PMID 8381532 DOI: 10.1073/Pnas.90.3.1107 |
0.465 |
|
| 1993 |
Stein B, Cogswell PC, Baldwin AS. Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction. Molecular and Cellular Biology. 13: 3964-74. PMID 8321203 DOI: 10.1128/mcb.13.7.3964-3974.1993 |
0.382 |
|
| 1993 |
Beg AA, Baldwin AS. The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes & Development. 7: 2064-70. PMID 8224838 DOI: 10.1101/Gad.7.11.2064 |
0.428 |
|
| 1993 |
Stein B, Baldwin A, Ballard D, Greene W, Angel P, Herrlich P. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. The Embo Journal. 12: 3879-3891. DOI: 10.1002/J.1460-2075.1993.Tb06066.X |
0.465 |
|
| 1992 |
Le Beau MM, Ito C, Cogswell P, Espinosa R, Fernald AA, Baldwin AS. Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKBI) inhibitor of NF-kappa B to 4q24 and 14q13, respectively. Genomics. 14: 529-31. PMID 1427874 DOI: 10.1016/S0888-7543(05)80261-7 |
0.409 |
|
| 1992 |
Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA, Baldwin AS. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention. Genes & Development. 6: 1899-913. PMID 1340770 DOI: 10.1101/Gad.6.10.1899 |
0.428 |
|
| 1991 |
Baldwin AS, Azizkhan JC, Jensen DE, Beg AA, Coodly LR. Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts. Molecular and Cellular Biology. 11: 4943-51. PMID 1922027 DOI: 10.1128/mcb.11.10.4943-4951.1991 |
0.465 |
|
| 1991 |
Haskill S, Beg AA, Tompkins SM, Morris JS, Yurochko AD, Sampson-Johannes A, Mondal K, Ralph P, Baldwin AS. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell. 65: 1281-9. PMID 1829648 DOI: 10.1016/0092-8674(91)90022-Q |
0.479 |
|
| 1988 |
Baldwin AS, Sharp PA. Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. Proceedings of the National Academy of Sciences of the United States of America. 85: 723-7. PMID 3422454 DOI: 10.1073/pnas.85.3.723 |
0.317 |
|
| 1987 |
Baldwin AS, Sharp PA. Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Molecular and Cellular Biology. 7: 305-13. PMID 3561391 DOI: 10.1128/mcb.7.1.305-313.1987 |
0.325 |
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