Albert S. Baldwin - Publications

Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Genetics, Molecular Biology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Hsia HC, Hutti JE, Baldwin AS. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity. The Journal of Biological Chemistry. PMID 28188292 DOI: 10.1074/jbc.M116.771964  0.48
2016 Rinkenbaugh AL, Cogswell PC, Calamini B, Dunn DE, Persson AI, Weiss WA, Lo DC, Baldwin AS. IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance. Oncotarget. PMID 27732951 DOI: 10.18632/oncotarget.12507  0.4
2016 Dan HC, Antonia RJ, Baldwin AS. PI3K/Akt promotes feedforward mTORC2 activation through IKKα. Oncotarget. PMID 27027448 DOI: 10.18632/oncotarget.8383  0.96
2015 Zhang J, Li L, Baldwin AS, Friedman AD, Paz-Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. Plos One. 10: e0130441. PMID 26102347 DOI: 10.1371/journal.pone.0130441  0.96
2015 Bassères DS, Baldwin AS. Using RNA interference in lung cancer cells to target the IKK-NF-κB pathway. Methods in Molecular Biology (Clifton, N.J.). 1280: 447-58. PMID 25736766 DOI: 10.1007/978-1-4939-2422-6_27  0.96
2014 Dan HC, Ebbs A, Pasparakis M, Van Dyke T, Basseres DS, Baldwin AS. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα). The Journal of Biological Chemistry. 289: 25227-40. PMID 24990947 DOI: 10.1074/jbc.M114.554881  0.96
2014 Bassères DS, Ebbs A, Cogswell PC, Baldwin AS. IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity. Genes & Cancer. 5: 41-55. PMID 24955217  0.96
2014 Bradford JW, Baldwin AS. IKK/nuclear factor-kappaB and oncogenesis: roles in tumor-initiating cells and in the tumor microenvironment. Advances in Cancer Research. 121: 125-45. PMID 24889530 DOI: 10.1016/B978-0-12-800249-0.00003-2  0.96
2014 Habineza Ndikuyeze G, Gaurnier-Hausser A, Patel R, Baldwin AS, May MJ, Flood P, Krick E, Propert KJ, Mason NJ. A phase I clinical trial of systemically delivered NEMO binding domain peptide in dogs with spontaneous activated B-cell like diffuse large B-cell lymphoma. Plos One. 9: e95404. PMID 24798348 DOI: 10.1371/journal.pone.0095404  0.96
2014 Fulton LM, Taylor NA, Coghill JM, West ML, Föger N, Bear JE, Baldwin AS, Panoskaltsis-Mortari A, Serody JS. Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease. European Journal of Immunology. 44: 1662-71. PMID 24752751 DOI: 10.1002/eji.201344155  0.96
2014 Kegelman TP, Das SK, Hu B, Bacolod MD, Fuller CE, Menezes ME, Emdad L, Dasgupta S, Baldwin AS, Bruce JN, Dent P, Pellecchia M, Sarkar D, Fisher PB. MDA-9/syntenin is a key regulator of glioma pathogenesis. Neuro-Oncology. 16: 50-61. PMID 24305713 DOI: 10.1093/neuonc/not157  0.96
2014 Kendellen MF, Bradford JW, Lawrence CL, Clark KS, Baldwin AS. Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells. Oncogene. 33: 1297-305. PMID 23474754 DOI: 10.1038/onc.2013.64  0.96
2013 Wu C, Haynes EM, Asokan SB, Simon JM, Sharpless NE, Baldwin AS, Davis IJ, Johnson GL, Bear JE. Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signaling. The Journal of Cell Biology. 203: 907-16. PMID 24344184 DOI: 10.1083/jcb.201306032  0.96
2013 Cooper MJ, Cox NJ, Zimmerman EI, Dewar BJ, Duncan JS, Whittle MC, Nguyen TA, Jones LS, Ghose Roy S, Smalley DM, Kuan PF, Richards KL, Christopherson RI, Jin J, Frye SV, ... ... Baldwin AS, et al. Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia. Plos One. 8: e66755. PMID 23826126 DOI: 10.1371/journal.pone.0066755  0.96
2013 Xu D, Cobb MG, Gavilano L, Witherspoon SM, Williams D, White CD, Taverna P, Bednarski BK, Kim HJ, Baldwin AS, Baines AT. Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine. Cancer Biology & Therapy. 14: 492-501. PMID 23760491 DOI: 10.4161/cbt.24343  0.96
2013 Stein SJ, Baldwin AS. Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function. Blood. 121: 5015-24. PMID 23670180 DOI: 10.1182/blood-2013-02-486142  0.96
2013 Bang D, Wilson W, Ryan M, Yeh JJ, Baldwin AS. GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB. Cancer Discovery. 3: 690-703. PMID 23547054 DOI: 10.1158/2159-8290.CD-12-0541  0.96
2012 Chan IS, Guy CD, Chen Y, Lu J, Swiderska-Syn M, Michelotti GA, Karaca G, Xie G, Krüger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma. Cancer Research. 72: 6344-50. PMID 23066040 DOI: 10.1158/0008-5472.CAN-12-1068  0.96
2012 Zhao YG, Wang Y, Guo Z, Gu AD, Dan HC, Baldwin AS, Hao W, Wan YY. Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway. Journal of Immunology (Baltimore, Md. : 1950). 189: 4417-25. PMID 22993204 DOI: 10.4049/jimmunol.1200919  0.96
2012 Allen JL, Fore MS, Wooten J, Roehrs PA, Bhuiya NS, Hoffert T, Sharf A, Deal AM, Armistead P, Coghill J, Gabriel DA, Irons R, Essenmacher A, Shea TC, Richards K, ... ... Baldwin AS, et al. B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways. Blood. 120: 2529-36. PMID 22896003 DOI: 10.1182/blood-2012-06-438911  0.96
2012 Hutti JE, Porter MA, Cheely AW, Cantley LC, Wang X, Kireev D, Baldwin AS, Janzen WP. Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε. Plos One. 7: e41494. PMID 22859992 DOI: 10.1371/journal.pone.0041494  0.96
2012 Hutti JE, Pfefferle AD, Russell SC, Sircar M, Perou CM, Baldwin AS. Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation. Cancer Research. 72: 3260-9. PMID 22552288 DOI: 10.1158/0008-5472.CAN-11-4141  0.96
2012 Baldwin AS. Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer. Immunological Reviews. 246: 327-45. PMID 22435564 DOI: 10.1111/j.1600-065X.2012.01095.x  0.96
2012 Santhekadur PK, Das SK, Gredler R, Chen D, Srivastava J, Robertson C, Baldwin AS, Fisher PB, Sarkar D. Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221. The Journal of Biological Chemistry. 287: 13952-8. PMID 22396537 DOI: 10.1074/jbc.M111.321646  0.96
2012 Comb WC, Hutti JE, Cogswell P, Cantley LC, Baldwin AS. p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation. Molecular Cell. 45: 719-30. PMID 22342344 DOI: 10.1016/j.molcel.2012.01.010  0.96
2012 Awwad Y, Geng T, Baldwin AS, Lu C. Observing single cell NF-κB dynamics under stimulant concentration gradient. Analytical Chemistry. 84: 1224-8. PMID 22263650 DOI: 10.1021/ac203209t  0.96
2011 Tanaka K, Babic I, Nathanson D, Akhavan D, Guo D, Gini B, Dang J, Zhu S, Yang H, De Jesus J, Amzajerdi AN, Zhang Y, Dibble CC, Dan H, Rinkenbaugh A, ... ... Baldwin AS, et al. Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance. Cancer Discovery. 1: 524-38. PMID 22145100 DOI: 10.1158/2159-8290.CD-11-0124  0.96
2011 Dooher JE, Paz-Priel I, Houng S, Baldwin AS, Friedman AD. C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction. Molecular Cancer Research : McR. 9: 1395-405. PMID 21813505 DOI: 10.1158/1541-7786.MCR-11-0072  0.96
2011 Stein SJ, Baldwin AS. NF-κB suppresses ROS levels in BCR-ABL(+) cells to prevent activation of JNK and cell death. Oncogene. 30: 4557-66. PMID 21625221 DOI: 10.1038/onc.2011.156  0.96
2011 Gaurnier-Hausser A, Patel R, Baldwin AS, May MJ, Mason NJ. NEMO-binding domain peptide inhibits constitutive NF-κB activity and reduces tumor burden in a canine model of relapsed, refractory diffuse large B-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4661-71. PMID 21610150 DOI: 10.1158/1078-0432.CCR-10-3310  0.96
2011 Rinkenbaugh AL, Baldwin AS. Monoallelic deletion of NFKBIA in glioblastoma: when less is more. Cancer Cell. 19: 163-5. PMID 21316598 DOI: 10.1016/j.ccr.2011.01.045  0.96
2011 Peterson JM, Kline W, Canan BD, Ricca DJ, Kaspar B, Delfín DA, DiRienzo K, Clemens PR, Robbins PD, Baldwin AS, Flood P, Kaumaya P, Freitas M, Kornegay JN, Mendell JR, et al. Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy. Molecular Medicine (Cambridge, Mass.). 17: 508-15. PMID 21267511 DOI: 10.2119/molmed.2010.00263  0.96
2011 Comb WC, Cogswell P, Sitcheran R, Baldwin AS. IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene. 30: 1727-32. PMID 21151171 DOI: 10.1038/onc.2010.553  0.96
2011 O'Neil BH, Funkhouser WK, Calvo BF, Meyers MO, Kim HJ, Goldberg RM, Bernard SA, Caskey L, Deal AM, Wright F, Baldwin AS, Tepper JE. Nuclear factor κ-light chain-enhancer of activated B cells is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiotheraphy. International Journal of Radiation Oncology, Biology, Physics. 80: 705-11. PMID 20630669 DOI: 10.1016/j.ijrobp.2010.02.063  0.96
2011 Wysong A, Asher SA, Yin X, Gore MR, Weinstein L, Guttridge DC, Baldwin AS, Couch ME, Willis MS. Selective inhibition of NF-kappa-B with NBD peptide reduces tumor- induced wasting in a murine model of cancer cachexia in vivo Journal of Cancer Science and Therapy. 3: 022-029. DOI: 10.4172/1948-5956.1000052  0.96
2010 Balasubramani A, Shibata Y, Crawford GE, Baldwin AS, Hatton RD, Weaver CT. Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. Immunity. 33: 35-47. PMID 20643337 DOI: 10.1016/j.immuni.2010.07.004  0.96
2010 Puvvada SD, Funkhouser WK, Greene K, Deal A, Chu H, Baldwin AS, Tepper JE, O'Neil BH. NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. Oncology. 78: 181-8. PMID 20414006 DOI: 10.1159/000313697  0.96
2010 Bassères DS, Ebbs A, Levantini E, Baldwin AS. Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis. Cancer Research. 70: 3537-46. PMID 20406971 DOI: 10.1158/0008-5472.CAN-09-4290  0.96
2010 Adli M, Merkhofer E, Cogswell P, Baldwin AS. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway. Plos One. 5: e9428. PMID 20195534 DOI: 10.1371/journal.pone.0009428  0.96
2010 Merkhofer EC, Cogswell P, Baldwin AS. Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene. 29: 1238-48. PMID 19946332 DOI: 10.1038/onc.2009.410  0.96
2009 Bednarski BK, Baldwin AS, Kim HJ. Addressing reported pro-apoptotic functions of NF-kappaB: targeted inhibition of canonical NF-kappaB enhances the apoptotic effects of doxorubicin. Plos One. 4: e6992. PMID 19746155 DOI: 10.1371/journal.pone.0006992  0.96
2009 Raetzsch CF, Brooks NL, Alderman JM, Moore KS, Hosick PA, Klebanov S, Akira S, Bear JE, Baldwin AS, Mackman N, Combs TP. Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway. Hepatology (Baltimore, Md.). 50: 592-600. PMID 19492426 DOI: 10.1002/hep.22999  0.96
2009 O'Shaughnessy MJ, Vogtenhuber C, Sun K, Sitcheran R, Baldwin AS, Murphy WJ, Dang L, Jaffee B, Palmer E, Serody JS, Blazar BR. Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 452-62. PMID 19260829 DOI: 10.1111/j.1600-6143.2008.02533.x  0.96
2009 Laurenzana A, Petruccelli LA, Pettersson F, Figueroa ME, Melnick A, Baldwin AS, Paoletti F, Miller WH. Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells. Cancer Research. 69: 55-64. PMID 19117987 DOI: 10.1158/0008-5472.CAN-08-0245  0.96
2008 Moss NC, Tang RH, Willis M, Stansfield WE, Baldwin AS, Selzman CH. Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection. The Journal of Thoracic and Cardiovascular Surgery. 136: 1274-9. PMID 19026814 DOI: 10.1016/j.jtcvs.2008.07.041  0.96
2008 Wilson W, Baldwin AS. Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer. Cancer Research. 68: 8156-63. PMID 18829575 DOI: 10.1158/0008-5472.CAN-08-1061  0.96
2008 Goetz CA, Baldwin AS. NF-kappaB pathways in the immune system: control of the germinal center reaction. Immunologic Research. 41: 233-47. PMID 18670738 DOI: 10.1007/s12026-008-8033-1  0.96
2008 Bednarski BK, Ding X, Coombe K, Baldwin AS, Kim HJ. Active roles for inhibitory kappaB kinases alpha and beta in nuclear factor-kappaB-mediated chemoresistance to doxorubicin. Molecular Cancer Therapeutics. 7: 1827-35. PMID 18644995 DOI: 10.1158/1535-7163.MCT-08-0321  0.96
2008 Sitcheran R, Comb WC, Cogswell PC, Baldwin AS. Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB. Molecular and Cellular Biology. 28: 5061-70. PMID 18541671 DOI: 10.1128/MCB.00578-08  0.96
2008 Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes & Development. 22: 1490-500. PMID 18519641 DOI: 10.1101/gad.1662308  0.96
2008 Dan HC, Baldwin AS. Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt. Journal of Immunology (Baltimore, Md. : 1950). 180: 7582-9. PMID 18490760  0.96
2008 Tang RH, Zheng XL, Callis TE, Stansfield WE, He J, Baldwin AS, Wang DZ, Selzman CH. Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 105: 3362-7. PMID 18296632 DOI: 10.1073/pnas.0705842105  0.96
2008 Steinbrecher KA, Harmel-Laws E, Sitcheran R, Baldwin AS. Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation. Journal of Immunology (Baltimore, Md. : 1950). 180: 2588-99. PMID 18250470  0.96
2008 Duncan EA, Goetz CA, Stein SJ, Mayo KJ, Skaggs BJ, Ziegelbauer K, Sawyers CL, Baldwin AS. IkappaB kinase beta inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells. Molecular Cancer Therapeutics. 7: 391-7. PMID 18245668 DOI: 10.1158/1535-7163.MCT-07-0305  0.96
2008 Witcher M, Pettersson F, Dupéré-Richer D, Padovani A, Summers-Deluca L, Baldwin AS, Miller WH. Retinoic acid modulates chromatin to potentiate tumor necrosis factor alpha signaling on the DIF2 promoter. Nucleic Acids Research. 36: 435-43. PMID 18039708 DOI: 10.1093/nar/gkm1058  0.96
2008 Stansfield WE, Tang RH, Moss NC, Baldwin AS, Willis MS, Selzman CH. Proteasome inhibition promotes regression of left ventricular hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 294: H645-50. PMID 18032525 DOI: 10.1152/ajpheart.00196.2007  0.96
2007 O'Neil BH, Bůzková P, Farrah H, Kashatus D, Sanoff H, Goldberg RM, Baldwin AS, Funkhouser WK. Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology. 72: 97-104. PMID 18025803 DOI: 10.1159/111116  0.96
2007 Davé SH, Tilstra JS, Matsuoka K, Li F, Karrasch T, Uno JK, Sepulveda AR, Jobin C, Baldwin AS, Robbins PD, Plevy SE. Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide. Journal of Immunology (Baltimore, Md. : 1950). 179: 7852-9. PMID 18025231  0.96
2007 Wang J, An H, Mayo MW, Baldwin AS, Yarbrough WG. LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB. Cancer Cell. 12: 239-51. PMID 17785205 DOI: 10.1016/j.ccr.2007.07.002  0.96
2007 Dan HC, Adli M, Baldwin AS. Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha. Cancer Research. 67: 6263-9. PMID 17616684 DOI: 10.1158/0008-5472.CAN-07-1232  0.96
2007 Gilbert MR, Carnathan DG, Cogswell PC, Lin L, Baldwin AS, Vilen BJ. Dendritic cells from lupus-prone mice are defective in repressing immunoglobulin secretion. Journal of Immunology (Baltimore, Md. : 1950). 178: 4803-10. PMID 17404261  0.96
2007 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, ... Baldwin AS, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/JCI30556  0.96
2007 Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin AS, Tisch RM. Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells. Blood. 109: 653-60. PMID 17008547 DOI: 10.1182/blood-2006-04-017368  0.96
2006 Adli M, Baldwin AS. IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation. The Journal of Biological Chemistry. 281: 26976-84. PMID 16840782 DOI: 10.1074/jbc.M603133200  0.84
2006 Duncan EA, Anest V, Cogswell P, Baldwin AS. The kinases MSK1 and MSK2 are required for epidermal growth factor-induced, but not tumor necrosis factor-induced, histone H3 Ser10 phosphorylation. The Journal of Biological Chemistry. 281: 12521-5. PMID 16517600 DOI: 10.1074/jbc.M513333200  0.72
2006 Kashatus D, Cogswell P, Baldwin AS. Expression of the Bcl-3 proto-oncogene suppresses p53 activation. Genes & Development. 20: 225-35. PMID 16384933 DOI: 10.1101/gad.1352206  0.72
2005 Steinbrecher KA, Wilson W, Cogswell PC, Baldwin AS. Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription. Molecular and Cellular Biology. 25: 8444-55. PMID 16166627 DOI: 10.1128/MCB.25.19.8444-8455.2005  0.88
2005 Sitcheran R, Gupta P, Fisher PB, Baldwin AS. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. The Embo Journal. 24: 510-20. PMID 15660126 DOI: 10.1038/sj.emboj.7600555  0.96
2004 Ventura JJ, Cogswell P, Flavell RA, Baldwin AS, Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes & Development. 18: 2905-15. PMID 15545623 DOI: 10.1101/gad.1223004  0.72
2004 Sarkar D, Lebedeva IV, Emdad L, Kang DC, Baldwin AS, Fisher PB. Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation. Cancer Research. 64: 7473-8. PMID 15492272 DOI: 10.1158/0008-5472.CAN-04-1772  0.96
2004 Hanson JL, Hawke NA, Kashatus D, Baldwin AS. The nuclear factor kappaB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer Research. 64: 7248-55. PMID 15492243 DOI: 10.1158/0008-5472.CAN-03-3898  0.96
2004 Loercher A, Lee TL, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS, Van Waes C. Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Research. 64: 6511-23. PMID 15374962 DOI: 10.1158/0008-5472.CAN-04-0852  0.96
2004 Anest V, Cogswell PC, Baldwin AS. IkappaB kinase alpha and p65/RelA contribute to optimal epidermal growth factor-induced c-fos gene expression independent of IkappaBalpha degradation. The Journal of Biological Chemistry. 279: 31183-9. PMID 15155743 DOI: 10.1074/jbc.M404380200  0.4
2004 Kurenova E, Xu LH, Yang X, Baldwin AS, Craven RJ, Hanks SK, Liu ZG, Cance WG. Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Molecular and Cellular Biology. 24: 4361-71. PMID 15121855 DOI: 10.1128/MCB.24.10.4361-4371.2004  0.96
2004 Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS, Tisch R. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood. 104: 1100-9. PMID 15113757 DOI: 10.1182/blood-2003-12-4302  0.96
2003 Sitcheran R, Cogswell PC, Baldwin AS. NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes & Development. 17: 2368-73. PMID 14522944 DOI: 10.1101/gad.1114503  0.52
2003 Hanson JL, Anest V, Reuther-Madrid J, Baldwin AS. Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathways. The Journal of Biological Chemistry. 278: 34910-7. PMID 12851413 DOI: 10.1074/jbc.M304189200  0.96
2003 Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature. 423: 659-63. PMID 12789343 DOI: 10.1038/nature01648  0.96
2003 Weaver KD, Yeyeodu S, Cusack JC, Baldwin AS, Ewend MG. Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas. Journal of Neuro-Oncology. 61: 187-96. PMID 12675310 DOI: 10.1023/A:1022554824129  0.96
2003 Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS, Tisch R. NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. Journal of Immunology (Baltimore, Md. : 1950). 170: 1770-80. PMID 12574341  0.96
2003 Cogswell PC, Kashatus DF, Keifer JA, Guttridge DC, Reuther JY, Bristow C, Roy S, Nicholson DW, Baldwin AS. NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B. The Journal of Biological Chemistry. 278: 2963-8. PMID 12433922 DOI: 10.1074/jbc.M209995200  0.4
2002 Mayo MW, Madrid LV, Westerheide SD, Jones DR, Yuan XJ, Baldwin AS, Whang YE. PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit. The Journal of Biological Chemistry. 277: 11116-25. PMID 11799112 DOI: 10.1074/jbc.M108670200  0.96
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