Peter W. Laird - Publications

Biochemistry and Molecular Biology University of Southern California, Los Angeles, CA, United States 
Molecular Biology

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, ... ... Laird PW, et al. Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway. Cell Reports. 34: 108784. PMID 33626341 DOI: 10.1016/j.celrep.2021.108784  0.72
2021 Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, ... ... Laird PW, et al. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Reports. 34: 108707. PMID 33535033 DOI: 10.1016/j.celrep.2021.108707  0.72
2020 Wheeler DA, Takebe N, Hinoue T, Hoadley KA, Cardenas MF, Hamilton AM, Laird PW, Wang L, Johnson A, Dewal N, Miller V, Piñeyro D, Castro de Moura M, Esteller M, Shen H, et al. Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment. Cancer Cell. PMID 33217343 DOI: 10.1016/j.ccell.2020.10.015  0.8
2020 Coyne GO, Kummar S, Meehan RS, Do K, Collins JM, Anderson L, Ishii K, Takebe N, Zlott J, Juwara L, Piekarz R, Streicher H, Sharon E, Rubinstein L, Voth AR, ... ... Laird PW, et al. Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas. Oncotarget. 11: 3959-3971. PMID 33216844 DOI: 10.18632/oncotarget.27784  0.64
2020 Haider S, Tyekucheva S, Prandi D, Fox NS, Ahn J, Xu AW, Pantazi A, Park PJ, Laird PW, Sander C, Wang W, Demichelis F, Loda M, Boutros PC. Systematic Assessment of Tumor Purity and Its Clinical Implications. Jco Precision Oncology. 4. PMID 33015524 DOI: 10.1200/PO.20.00016  0.52
2020 Carrot-Zhang J, Chambwe N, Damrauer JS, Knijnenburg TA, Robertson AG, Yau C, Zhou W, Berger AC, Huang KL, Newberg JY, Mashl RJ, Romanel A, Sayaman RW, Demichelis F, Felau I, ... ... Laird PW, et al. Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer. Cancer Cell. 37: 639-654.e6. PMID 32396860 DOI: 10.1016/J.Ccell.2020.04.012  0.8
2020 Conley BA, Staudt L, Takebe N, Wheeler DA, Wang L, Cardenas MF, Korchina V, Zenklusen JC, McShane LM, Tricoli JV, Williams PM, Lubensky I, O'Sullivan-Coyne G, Kohn E, Little RF, ... ... Laird PW, et al. The Exceptional Responders Initiative: Feasibility of A National Cancer Institute Pilot Study. Journal of the National Cancer Institute. PMID 32339229 DOI: 10.1093/Jnci/Djaa061  0.8
2019 Davis Lynn BC, Bodelon C, Pfeiffer RM, Yang HP, Yang H, Lee M, Laird PW, Campan M, Weisenberger DJ, Murphy J, Sampson JN, Browne EP, Anderton DL, Sherman ME, Arcaro KF, et al. Differences in genome-wide DNA methylation profiles in breast milk by race and lactation duration. Cancer Prevention Research (Philadelphia, Pa.). PMID 31481539 DOI: 10.1158/1940-6207.Capr-19-0169  0.64
2019 Gao GF, Parker JS, Reynolds SM, Silva TC, Wang LB, Zhou W, Akbani R, Bailey M, Balu S, Berman BP, Brooks D, Chen H, Cherniack AD, Demchok JA, Ding L, ... ... Laird PW, et al. Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data. Cell Systems. 9: 24-34.e10. PMID 31344359 DOI: 10.1016/J.Cels.2019.06.006  0.8
2019 Liang W, Zhao Y, Huang W, Gao Y, Xu W, Tao J, Yang M, Li L, Ping W, Shen H, Fu X, Chen Z, Laird PW, Cai X, Fan JB, et al. Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA). Theranostics. 9: 2056-2070. PMID 31037156 DOI: 10.7150/Thno.28119  0.8
2019 Vander Schaaf NA, Oghamian S, Park JA, Kang L, Laird PW, Lee KH. In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression. Journal of Visualized Experiments : Jove. PMID 30985765 DOI: 10.3791/59235  0.8
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Laird PW, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898  0.8
2018 Zhou W, Triche TJ, Laird PW, Shen H. SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions. Nucleic Acids Research. PMID 30085201 DOI: 10.1093/Nar/Gky691  0.8
2018 Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, ... ... Laird PW, et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Reports. 23: 3392-3406. PMID 29898407 DOI: 10.1016/J.Celrep.2018.05.039  0.8
2018 Liu L, Toung JM, Jassowicz AF, Vijayaraghavan R, Kang H, Zhang R, Kruglyak KM, Huang HJ, Hinoue T, Shen H, Salathia N, Hong DS, Naing A, Subbiah V, Piha-Paul SA, ... ... Laird PW, et al. Targeted Methylation Sequencing of Plasma Cell-free DNA for Cancer Detection and Classification. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 29635542 DOI: 10.1093/Annonc/Mdy119  0.8
2018 Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, et al. The Immune Landscape of Cancer. Immunity. PMID 29628290 DOI: 10.1016/J.Immuni.2018.03.023  0.36
2018 Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, ... ... Laird PW, et al. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 173: 338-354.e15. PMID 29625051 DOI: 10.1016/J.Cell.2018.03.034  0.44
2018 Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, ... ... Laird PW, et al. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 173: 321-337.e10. PMID 29625050 DOI: 10.1016/J.Cell.2018.03.035  0.8
2018 Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, ... ... Laird PW, et al. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 173: 291-304.e6. PMID 29625048 DOI: 10.1016/J.Cell.2018.03.022  0.64
2018 Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, ... ... Laird PW, et al. Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell. PMID 29622466 DOI: 10.1016/J.Ccell.2018.03.010  0.64
2018 Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, ... ... Laird PW, et al. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports. 23: 239-254.e6. PMID 29617664 DOI: 10.1016/J.Celrep.2018.03.076  0.8
2018 Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, ... ... Laird PW, et al. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports. 23: 194-212.e6. PMID 29617660 DOI: 10.1016/J.Celrep.2018.03.063  0.8
2018 Zhou W, Dinh HQ, Ramjan Z, Weisenberger DJ, Nicolet CM, Shen H, Laird PW, Berman BP. DNA methylation loss in late-replicating domains is linked to mitotic cell division. Nature Genetics. PMID 29610480 DOI: 10.1038/S41588-018-0073-4  0.8
2018 Campan M, Weisenberger DJ, Trinh B, Laird PW. MethyLight and Digital MethyLight. Methods in Molecular Biology (Clifton, N.J.). 1708: 497-513. PMID 29224160 DOI: 10.1007/978-1-4939-7481-8_25  0.64
2017 Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, et al. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell. PMID 28988769 DOI: 10.1016/J.Cell.2017.09.007  0.64
2017 Lee KH, Oghamian S, Park JA, Kang L, Laird PW. The REMOTE-control system: a system for reversible and tunable control of endogenous gene expression in mice. Nucleic Acids Research. PMID 28981717 DOI: 10.1093/Nar/Gkx829  0.8
2017 Erdreich-Epstein A, Singh AR, Joshi S, Vega FM, Guo P, Xu J, Groshen S, Ye W, Millard M, Campan M, Morales G, Garlich JR, Laird PW, Seeger RC, Shimada H, et al. Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126. Oncotarget. 8: 52193-52210. PMID 28881723 DOI: 10.18632/Oncotarget.13386  0.56
2017 Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, ... ... Laird PW, et al. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nature Genetics. PMID 28825726 DOI: 10.1038/Ng.3934  0.8
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Laird PW, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 19: 2878-2880. PMID 28658632 DOI: 10.1016/J.Celrep.2017.06.008  0.64
2017 Huo D, Hu H, Rhie SK, Gamazon ER, Cherniack AD, Liu J, Yoshimatsu TF, Pitt JJ, Hoadley KA, Troester M, Ru Y, Lichtenberg T, Sturtz LA, Shelley CS, Benz CC, ... ... Laird PW, et al. Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas. Jama Oncology. PMID 28472234 DOI: 10.1001/Jamaoncol.2017.0595  0.52
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Laird PW, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 18: 2780-2794. PMID 28297679 DOI: 10.1016/J.Celrep.2017.02.033  0.64
2017 Cherniack AD, Shen H, Walter V, Stewart C, Murray BA, Bowlby R, Hu X, Ling S, Soslow RA, Broaddus RR, Zuna RE, Robertson G, Laird PW, Kucherlapati R, Mills GB, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 31: 411-423. PMID 28292439 DOI: 10.1016/J.Ccell.2017.02.010  0.8
2017 Azad NS, El-Khoueiry A, Yin J, Oberg AL, Flynn P, Adkins D, Sharma A, Weisenberger DJ, Brown T, Medvari P, Jones PA, Easwaran H, Kamel I, Bahary N, Kim G, ... ... Laird PW, et al. Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study. Oncotarget. PMID 28186961 DOI: 10.18632/Oncotarget.15108  0.96
2016 Troester MA, Hoadley KA, D'Arcy M, Cherniack AD, Stewart C, Koboldt DC, Robertson AG, Mahurkar S, Shen H, Wilkerson MD, Sandhu R, Johnson NB, Allison KH, Beck AH, Yau C, ... ... Laird PW, et al. DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas. Npj Breast Cancer. 2: 16007. PMID 28721375 DOI: 10.1038/npjbcancer.2016.7  0.8
2016 Connolly R, Li H, Jankowitz RC, Zhang Z, Rudek MA, Jeter SC, Slater S, Powers P, Wolff AC, Fetting JH, Brufsky AM, Piekarz R, Ahuja N, Laird PW, Shen H, et al. Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27979916 DOI: 10.1158/1078-0432.Ccr-16-1729  0.96
2016 Zhou W, Laird PW, Shen H. Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes. Nucleic Acids Research. PMID 27924034 DOI: 10.1093/Nar/Gkw967  0.8
2016 Erdreich-Epstein A, Singh AR, Joshi S, Vega FM, Guo P, Xu J, Groshen S, Ye W, Millard M, Campan M, Morales G, Garlich JR, Laird PW, Seeger RC, Shimada H, et al. Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126. Oncotarget. PMID 27907905 DOI: 10.18632/oncotarget.13386  0.56
2016 Rhie SK, Guo Y, Tak YG, Yao L, Shen H, Coetzee GA, Laird PW, Farnham PJ. Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits. Epigenetics & Chromatin. 9: 50. PMID 27833659 DOI: 10.1186/S13072-016-0102-4  0.8
2016 Lee KH, Laird PW. All Things in Moderation: Prevention of Intestinal Adenomas by DNA Hypomethylation. Cancer Prevention Research (Philadelphia, Pa.). PMID 27190044 DOI: 10.1158/1940-6207.Capr-16-0097  0.6
2016 Kim SE, Hinoue T, Kim MS, Sohn KJ, Cho RC, Weisenberger DJ, Laird PW, Kim YI. Effects of folylpolyglutamate synthase modulation on global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells. The Journal of Nutritional Biochemistry. 29: 27-35. PMID 26895662 DOI: 10.1016/J.Jnutbio.2015.10.019  1
2016 Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, ... ... Laird PW, et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164: 550-563. PMID 26824661 DOI: 10.1016/J.Cell.2015.12.028  1
2016 Bock C, Halbritter F, Carmona FJ, Tierling S, Datlinger P, Assenov Y, Berdasco M, Bergmann AK, Booher K, Busato F, Campan M, Dahl C, Dahmcke CM, Diep D, Fernández AF, ... ... Laird PW, et al. Quantitative comparison of DNA methylation assays for biomarker development and clinical applications Nature Biotechnology. 34: 726-737. DOI: 10.1038/Nbt.3605  1
2015 Ryland KE, Hawkins AG, Weisenberger DJ, Punj V, Borinstein SC, Laird PW, Martens JR, Lawlor ER. Promoter Methylation Analysis Reveals that KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation. Molecular Cancer Research : McR. PMID 26573141 DOI: 10.1158/1541-7786.Mcr-15-0343  1
2015 Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, ... ... Laird PW, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26536169 DOI: 10.1056/Nejmoa1505917  1
2015 Levine AJ, Phipps AI, Baron JA, Buchanan DD, Ahnen DJ, Cohen S, Lindor NM, Newcomb PA, Rosty C, Haile RW, Laird PW, Weisenberger DJ. Clinicopathological risk factor distributions for MLH1 promoter region methylation in CIMP positive tumors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26512054 DOI: 10.1158/1055-9965.Epi-15-0935  1
2015 Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, Zhang H, McLellan M, Yau C, Kandoth C, Bowlby R, Shen H, Hayat S, Fieldhouse R, Lester SC, ... ... Laird PW, et al. Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer. Cell. 163: 506-19. PMID 26451490 DOI: 10.1016/J.Cell.2015.09.033  1
2015 Graham RP, Vierkant RA, Tillmans LS, Wang AH, Laird PW, Weisenberger DJ, Lynch CF, French AJ, Slager SL, Raissian Y, Garcia JJ, Kerr SE, Eun Lee H, Thibodeau SN, Cerhan JR, et al. Tumor Budding in Colorectal Carcinoma: Confirmation of Prognostic Significance and Histologic Cutoff in a Population-based Cohort. The American Journal of Surgical Pathology. PMID 26200097 DOI: 10.1097/Pas.0000000000000504  1
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.8
2015 Yao L, Shen H, Laird PW, Farnham PJ, Berman BP. Inferring regulatory element landscapes and transcription factor networks from cancer methylomes. Genome Biology. 16: 105. PMID 25994056 DOI: 10.1186/S13059-015-0668-3  1
2015 Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Research. 25: 316-27. PMID 25650244 DOI: 10.1101/Gr.180612.114  1
2015 Weisenberger DJ, Levine AJ, Long TI, Buchanan DD, Walters R, Clendenning M, Rosty C, Joshi AD, Stern MC, Le Marchand L, Lindor NM, Daftary D, Gallinger S, Selander T, Bapat B, ... ... Laird PW, et al. Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 512-9. PMID 25587051 DOI: 10.1158/1055-9965.Epi-14-1161  1
2015 Kim SE, Hinoue T, Kim MS, Sohn KJ, Cho RC, Cole PD, Weisenberger DJ, Laird PW, Kim YI. γ-Glutamyl hydrolase modulation significantly influences global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells. Genes & Nutrition. 10: 444. PMID 25502219 DOI: 10.1007/S12263-014-0444-0  1
2015 Phipps AI, Limburg PJ, Baron JA, Burnett-Hartman AN, Weisenberger DJ, Laird PW, Sinicrope FA, Rosty C, Buchanan DD, Potter JD, Newcomb PA. Association between molecular subtypes of colorectal cancer and patient survival. Gastroenterology. 148: 77-87.e2. PMID 25280443 DOI: 10.1053/J.Gastro.2014.09.038  1
2014 Shen H, Leilabadi SN, Laird PW, Wong AK. Abstract 31: DNA methylation analysis of radiated skin reveals chonic inflammation with a predominance of polymorphonuclear granulocytes. Plastic and Reconstructive Surgery. 133: 42. PMID 25942142 DOI: 10.1097/01.prs.0000445064.02355.04  0.8
2014 Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... ... Laird PW, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014  1
2014 Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MD, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, ... ... Laird PW, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell. 158: 929-44. PMID 25109877 DOI: 10.1016/J.Cell.2014.06.049  1
2014 . Comprehensive molecular profiling of lung adenocarcinoma. Nature. 511: 543-50. PMID 25079552 DOI: 10.1038/Nature13385  1
2014 . Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 513: 202-9. PMID 25079317 DOI: 10.1038/Nature13480  1
2014 Wang X, Laird PW, Hinoue T, Groshen S, Siegmund KD. Non-specific filtering of beta-distributed data. Bmc Bioinformatics. 15: 199. PMID 24943962 DOI: 10.1186/1471-2105-15-199  1
2014 Knijnenburg TA, Ramsey SA, Berman BP, Kennedy KA, Smit AF, Wessels LF, Laird PW, Aderem A, Shmulevich I. Multiscale representation of genomic signals. Nature Methods. 11: 689-94. PMID 24727652 DOI: 10.1038/Nmeth.2924  1
2014 Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, ... ... Laird PW, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965  1
2013 Hakimi AA, Furberg H, Zabor EC, Jacobsen A, Schultz N, Ciriello G, Mikklineni N, Fiegoli B, Kim PH, Voss MH, Shen H, Laird PW, Sander C, Reuter VE, Motzer RJ, et al. An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma. Journal of the National Cancer Institute. 105: 1862-70. PMID 24285872 DOI: 10.1093/Jnci/Djt310  1
2013 Kim K, Punj V, Choi J, Heo K, Kim JM, Laird PW, An W. Gene dysregulation by histone variant H2A.Z in bladder cancer. Epigenetics & Chromatin. 6: 34. PMID 24279307 DOI: 10.1186/1756-8935-6-34  1
2013 Kim TM, Laird PW, Park PJ. The landscape of microsatellite instability in colorectal and endometrial cancer genomes. Cell. 155: 858-68. PMID 24209623 DOI: 10.1016/J.Cell.2013.10.015  1
2013 Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, Vancriekinge W, Demeyer T, Du Z, Parsana P, Rodgers K, Yen RW, Zahnow CA, Taube JM, Brahmer JR, ... ... Laird PW, et al. Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget. 4: 2067-79. PMID 24162015 DOI: 10.18632/Oncotarget.1542  1
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Laird PW, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  1
2013 Yoshihara K, Shahmoradgoli M, Martínez E, Vegesna R, Kim H, Torres-Garcia W, Treviño V, Shen H, Laird PW, Levine DA, Carter SL, Getz G, Stemke-Hale K, Mills GB, Verhaak RG. Inferring tumour purity and stromal and immune cell admixture from expression data. Nature Communications. 4: 2612. PMID 24113773 DOI: 10.1038/Ncomms3612  1
2013 Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhsng CZ, Wala J, Mermel CH, Sougnez C, Gabriel SB, Hernandez B, Shen H, Laird PW, et al. Pan-cancer patterns of somatic copy number alteration. Nature Genetics. 45: 1134-40. PMID 24071852 DOI: 10.1038/Ng.2760  1
2013 Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, et al. Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. Urology. 82: 253.e9-15. PMID 23806407 DOI: 10.1016/J.Urology.2013.04.010  1
2013 Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, et al. Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women. Gastroenterology. 145: 348-56.e1-2. PMID 23665275 DOI: 10.1053/J.Gastro.2013.05.001  1
2013 Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson G, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia New England Journal of Medicine. 368: 2059-2074. PMID 23634996 DOI: 10.1056/Nejmoa1301689  1
2013 Lange CP, Laird PW. Clinical applications of DNA methylation biomarkers in colorectal cancer. Epigenomics. 5: 105-8. PMID 23566085 DOI: 10.2217/Epi.13.4  1
2013 Shen H, Laird PW. Interplay between the cancer genome and epigenome. Cell. 153: 38-55. PMID 23540689 DOI: 10.1016/J.Cell.2013.03.008  1
2013 Triche TJ, Weisenberger DJ, Van Den Berg D, Laird PW, Siegmund KD. Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Research. 41: e90. PMID 23476028 DOI: 10.1093/Nar/Gkt090  1
2013 Creighton CJ, Morgan M, Gunaratne PH, Wheeler DA, Gibbs RA, Robertson G, Chu A, Beroukhim R, Cibulskis K, Signoretti S, Vandin F, Wu HT, Raphael BJ, Verhaak RGW, Tamboli P, ... ... Laird PW, et al. Comprehensivemolecular characterization of clear cell renal cell carcinoma Nature. 499: 43-49. DOI: 10.1038/Nature12222  1
2012 Lange CP, Campan M, Hinoue T, Schmitz RF, van der Meulen-de Jong AE, Slingerland H, Kok PJ, van Dijk CM, Weisenberger DJ, Shen H, Tollenaar RA, Laird PW. Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer. Plos One. 7: e50266. PMID 23209692 DOI: 10.1371/Journal.Pone.0050266  1
2012 Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA. A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Research. 72: 6319-24. PMID 23188507 DOI: 10.1158/0008-5472.Can-12-3658  1
2012 Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, et al. Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study. Nutrition and Cancer. 64: 899-910. PMID 23061900 DOI: 10.1080/01635581.2012.714833  1
2012 Zhang S, Liu CC, Li W, Shen H, Laird PW, Zhou XJ. Discovery of multi-dimensional modules by integrative analysis of cancer genomic data. Nucleic Acids Research. 40: 9379-91. PMID 22879375 DOI: 10.1093/Nar/Gks725  1
2012 Liu Y, Siegmund KD, Laird PW, Berman BP. Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data. Genome Biology. 13: R61. PMID 22784381 DOI: 10.1186/Gb-2012-13-7-R61  1
2012 Cortessis VK, Thomas DC, Levine AJ, Breton CV, Mack TM, Siegmund KD, Haile RW, Laird PW. Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Human Genetics. 131: 1565-89. PMID 22740325 DOI: 10.1007/S00439-012-1189-8  1
2012 Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, et al. Absolute quantification of somatic DNA alterations in human cancer. Nature Biotechnology. 30: 413-21. PMID 22544022 DOI: 10.1038/Nbt.2203  1
2012 Shen H, Laird PW. In epigenetic therapy, less is more. Cell Stem Cell. 10: 353-4. PMID 22482500 DOI: 10.1016/J.Stem.2012.03.012  1
2012 Levine AJ, Win AK, Buchanan DD, Jenkins MA, Baron JA, Young JP, Long TI, Weisenberger DJ, Laird PW, McCall RL, Duggan DJ, Haile RW. Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry. Cancer Prevention Research (Philadelphia, Pa.). 5: 328-35. PMID 22144422 DOI: 10.1158/1940-6207.Capr-11-0419  1
2012 Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, Noushmehr H, Lange CP, van Dijk CM, Tollenaar RA, Van Den Berg D, Laird PW. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nature Genetics. 44: 40-6. PMID 22120008 DOI: 10.1038/Ng.969  1
2012 Limsui D, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, et al. Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women. Gut. 61: 1299-305. PMID 22027477 DOI: 10.1136/Gutjnl-2011-300719  1
2012 Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Research. 22: 271-82. PMID 21659424 DOI: 10.1101/gr.117523.110  1
2011 Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, ... ... Laird PW, et al. Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. Plos One. 6: e28141. PMID 22163280 DOI: 10.1371/Journal.Pone.0028141  1
2011 Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H, Baker J, Baker D, Munoz MB, Beil S, Benvenisty N, Ben-Yosef D, Biancotti JC, Bosman A, ... ... Laird PW, et al. Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nature Biotechnology. 29: 1132-44. PMID 22119741 DOI: 10.1038/Nbt.2051  1
2011 Cortessis VK, Siegmund K, Houshdaran S, Laird PW, Sokol RZ. Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducible. Fertility and Sterility. 96: 1325-30. PMID 22035967 DOI: 10.1016/J.Fertnstert.2011.09.036  1
2011 Wang X, Kang GH, Campan M, Weisenberger DJ, Long TI, Cozen W, Bernstein L, Wu AH, Siegmund KD, Shibata D, Laird PW. Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors. Plos One. 6: e25985. PMID 22028801 DOI: 10.1371/Journal.Pone.0025985  1
2011 Razzak AA, Oxentenko AS, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Slager SL, Smyrk TC, Thibodeau SN, et al. Alcohol intake and colorectal cancer risk by molecularly defined subtypes in a prospective study of older women. Cancer Prevention Research (Philadelphia, Pa.). 4: 2035-43. PMID 21900595 DOI: 10.1158/1940-6207.Capr-11-0276  1
2011 Rakovski C, Weisenberger DJ, Marjoram P, Laird PW, Siegmund KD. Modeling measurement error in tumor characterization studies. Bmc Bioinformatics. 12: 284. PMID 21752297 DOI: 10.1186/1471-2105-12-284  1
2011 Oghamian S, Sodir NM, Bashir MU, Shen H, Cullins AE, Carroll CA, Kundu P, Shibata D, Laird PW. Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice. Carcinogenesis. 32: 829-35. PMID 21362628 DOI: 10.1093/Carcin/Bgr039  1
2011 Protiva P, Mason JB, Liu Z, Hopkins ME, Nelson C, Marshall JR, Lambrecht RW, Pendyala S, Kopelovich L, Kim M, Kleinstein SH, Laird PW, Lipkin M, Holt PR. Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 4: 530-43. PMID 21321062 DOI: 10.1158/1940-6207.Capr-10-0143  1
2011 Rumilla K, Schowalter KV, Lindor NM, Thomas BC, Mensink KA, Gallinger S, Holter S, Newcomb PA, Potter JD, Jenkins MA, Hopper JL, Long TI, Weisenberger DJ, Haile RW, Casey G, ... Laird PW, et al. Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. The Journal of Molecular Diagnostics : Jmd. 13: 93-9. PMID 21227399 DOI: 10.1016/J.Jmoldx.2010.11.011  1
2010 Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, et al. Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer. Plos One. 5: e13314. PMID 20967208 DOI: 10.1371/Journal.Pone.0013314  1
2010 Wolff EM, Chihara Y, Pan F, Weisenberger DJ, Siegmund KD, Sugano K, Kawashima K, Laird PW, Jones PA, Liang G. Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue. Cancer Research. 70: 8169-78. PMID 20841482 DOI: 10.1158/0008-5472.Can-10-1335  1
2010 Chung TL, Brena RM, Kolle G, Grimmond SM, Berman BP, Laird PW, Pera MF, Wolvetang EJ. Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. Stem Cells (Dayton, Ohio). 28: 1848-55. PMID 20687155 DOI: 10.1002/Stem.493  1
2010 Toth Z, Maglinte DT, Lee SH, Lee HR, Wong LY, Brulois KF, Lee S, Buckley JD, Laird PW, Marquez VE, Jung JU. Epigenetic analysis of KSHV latent and lytic genomes. Plos Pathogens. 6: e1001013. PMID 20661424 DOI: 10.1371/Journal.Ppat.1001013  1
2010 Dafou D, Grun B, Sinclair J, Lawrenson K, Benjamin EC, Hogdall E, Kruger-Kjaer S, Christensen L, Sowter HM, Al-Attar A, Edmondson R, Darby S, Berchuck A, Laird PW, Pearce CL, et al. Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers. Neoplasia (New York, N.Y.). 12: 579-89. PMID 20651987 DOI: 10.1593/Neo.10340  1
2010 Limsui D, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, et al. Cigarette smoking and colorectal cancer risk by molecularly defined subtypes. Journal of the National Cancer Institute. 102: 1012-22. PMID 20587792 DOI: 10.1093/Jnci/Djq201  1
2010 Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, ... ... Laird PW, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 17: 510-22. PMID 20399149 DOI: 10.1016/J.Ccr.2010.03.017  1
2010 Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW. DNA methylation as a biomarker for cardiovascular disease risk. Plos One. 5: e9692. PMID 20300621 DOI: 10.1371/Journal.Pone.0009692  1
2010 Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, ... ... Laird PW, et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Research. 20: 440-6. PMID 20219944 DOI: 10.1101/Gr.103606.109  1
2010 Houshdaran S, Hawley S, Palmer C, Campan M, Olsen MN, Ventura AP, Knudsen BS, Drescher CW, Urban ND, Brown PO, Laird PW. DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines. Plos One. 5: e9359. PMID 20179752 DOI: 10.1371/Journal.Pone.0009359  1
2010 Laird PW. Principles and challenges of genomewide DNA methylation analysis. Nature Reviews. Genetics. 11: 191-203. PMID 20125086 DOI: 10.1038/Nrg2732  1
2010 Wu AH, Siegmund KD, Long TI, Cozen W, Wan P, Tseng CC, Shibata D, Laird PW. Hormone therapy, DNA methylation and colon cancer. Carcinogenesis. 31: 1060-7. PMID 20064828 DOI: 10.1093/Carcin/Bgq009  1
2009 Laird PW. The USC Epigenome Center. Epigenomics. 1: 29-31. PMID 22122635 DOI: 10.2217/Epi.09.12  1
2009 Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW. Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling. Plos One. 4: e8357. PMID 20027224 DOI: 10.1371/Journal.Pone.0008357  1
2009 Gaudet MM, Campan M, Figueroa JD, Yang XR, Lissowska J, Peplonska B, Brinton LA, Rimm DL, Laird PW, Garcia-Closas M, Sherman ME. DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 3036-43. PMID 19861523 DOI: 10.1158/1055-9965.Epi-09-0678  1
2009 Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Human Molecular Genetics. 18: 4808-17. PMID 19776032 DOI: 10.1093/Hmg/Ddp445  1
2009 Berman BP, Weisenberger DJ, Laird PW. Locking in on the human methylome. Nature Biotechnology. 27: 341-2. PMID 19352369 DOI: 10.1038/Nbt0409-341  1
2009 Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI. The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification. International Journal of Cancer. Journal International Du Cancer. 124: 1999-2005. PMID 19123462 DOI: 10.1002/Ijc.24003  1
2009 Campan M, Weisenberger DJ, Trinh B, Laird PW. MethyLight. Methods in Molecular Biology (Clifton, N.J.). 507: 325-37. PMID 18987824 DOI: 10.1007/978-1-59745-522-0_23  1
2008 Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long T, Laird PW, Marquez VE, Jones PA. Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prevention Research (Philadelphia, Pa.). 1: 233-40. PMID 19138966 DOI: 10.1158/1940-6207.Capr-07-0008  1
2008 Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor N, Young J, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey G, Levine AJ, Le Marchand L, Gallinger S, ... ... Laird PW, et al. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3208-15. PMID 18990764 DOI: 10.1158/1055-9965.Epi-08-0512  1
2008 McIntosh M, Anderson G, Drescher C, Hanash S, Urban N, Brown P, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C. Ovarian cancer early detection claims are biased. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7574; author reply 7. PMID 18948385 DOI: 10.1158/1078-0432.Ccr-08-0623  1
2008 Lopes EC, Valls E, Figueroa ME, Mazur A, Meng FG, Chiosis G, Laird PW, Schreiber-Agus N, Greally JM, Prokhortchouk E, Melnick A. Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines. Cancer Research. 68: 7258-63. PMID 18794111 DOI: 10.1158/0008-5472.Can-08-0344  1
2008 Jones PA, Archer TK, Baylin SB, Beck S, Berger S, Bernstein BE, Carpten JD, Clark SJ, Costello JF, Doerge RW, Esteller M, Feinberg AP, Gingeras TR, Greally JM, Henikoff S, ... ... Laird PW, et al. Moving AHEAD with an international human epigenome project Nature. 454: 711-715. PMID 18685699 DOI: 10.1038/454711A  1
2008 Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Research. 36: 4689-98. PMID 18628296 DOI: 10.1093/nar/gkn455  1
2008 Anglim PP, Galler JS, Koss MN, Hagen JA, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. Molecular Cancer. 7: 62. PMID 18616821 DOI: 10.1186/1476-4598-7-62  1
2008 Byun HM, Choi SH, Laird PW, Trinh B, Siddiqui MA, Marquez VE, Yang AS. 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. Cancer Letters. 266: 238-48. PMID 18499340 DOI: 10.1016/J.Canlet.2008.02.069  1
2008 Pike BL, Greiner TC, Wang X, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim M, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, ... Laird PW, et al. DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status. Leukemia. 22: 1035-43. PMID 18288132 DOI: 10.1038/Leu.2008.18  1
2008 Kang GH, Lee S, Cho NY, Gandamihardja T, Long TI, Weisenberger DJ, Campan M, Laird PW. DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 161-70. PMID 18158559 DOI: 10.1038/Labinvest.3700707  1
2007 Houshdaran S, Cortessis VK, Siegmund K, Yang A, Laird PW, Sokol RZ. Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm. Plos One. 2: e1289. PMID 18074014 DOI: 10.1371/Journal.Pone.0001289  1
2007 Liu Z, Choi SW, Crott JW, Keyes MK, Jang H, Smith DE, Kim M, Laird PW, Bronson R, Mason JB. Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon. The Journal of Nutrition. 137: 2701-8. PMID 18029487 DOI: 10.1093/Jn/137.12.2701  1
2007 Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma. Molecular Cancer. 6: 70. PMID 17967182 DOI: 10.1186/1476-4598-6-70  1
2007 Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. Plos One. 2: e895. PMID 17878930 DOI: 10.1371/Journal.Pone.0000895  1
2007 Tsou JA, Galler JS, Wali A, Ye W, Siegmund KD, Groshen S, Laird PW, Turla S, Koss MN, Pass HI, Laird-Offringa IA. DNA methylation profile of 28 potential marker loci in malignant mesothelioma. Lung Cancer (Amsterdam, Netherlands). 58: 220-30. PMID 17659810 DOI: 10.1016/J.Lungcan.2007.06.015  1
2007 Chen H, Xia M, Lin M, Yang H, Kuhlenkamp J, Li T, Sodir NM, Chen YH, Josef-Lenz H, Laird PW, Clarke S, Mato JM, Lu SC. Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. Gastroenterology. 133: 207-18. PMID 17631143 DOI: 10.1053/J.Gastro.2007.03.114  1
2007 Feng Q, Hawes SE, Stern JE, Dem A, Sow PS, Dembele B, Toure P, Sova P, Laird PW, Kiviat NB. Promoter hypermethylation of tumor suppressor genes in urine from patients with cervical neoplasia. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1178-84. PMID 17548682 DOI: 10.1158/1055-9965.Epi-06-0694  1
2007 Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA. The role of DNA methylation in the development and progression of lung adenocarcinoma. Disease Markers. 23: 5-30. PMID 17325423 DOI: 10.1155/2007/985474  1
2007 Kohonen-Corish MRJ, Sigglekow ND, Susanto J, Chapuis PH, Bokey EL, Dent OF, Chan C, Lin BPC, Seng TJ, Laird PW, Young J, Leggett BA, Jass JR, Sutherland RL. Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer Oncogene. 26: 4435-4441. PMID 17260021 DOI: 10.1038/Sj.Onc.1210210  1
2007 Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young J, Jacobs I, Laird PW. Epigenetic stem cell signature in cancer. Nature Genetics. 39: 157-8. PMID 17200673 DOI: 10.1038/Ng1941  1
2007 Laird PW, Bibikova M, Fan JB. High-throughput DNA methylation Genetic Engineering and Biotechnology News. 27: 25.  1
2007 Laird PW, Bibikova M, Fan JB. Assay: High-throughput DNA methylation Genetic Engineering and Biotechnology News. 27.  1
2006 Wong HL, Byun HM, Kwan JM, Campan M, Ingles SA, Laird PW, Yang AS. Rapid and quantitative method of allele-specific DNA methylation analysis. Biotechniques. 41: 734-9. PMID 17191619 DOI: 10.2144/000112305  1
2006 Sodir NM, Chen X, Park R, Nickel AE, Conti PS, Moats R, Bading JR, Shibata D, Laird PW. Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. Cancer Research. 66: 8430-8. PMID 16951153 DOI: 10.1158/0008-5472.Can-06-1437  1
2006 Ogino S, Odze RD, Kawasaki T, Brahmandam M, Kirkner GJ, Laird PW, Loda M, Fuchs CS. Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma. The American Journal of Surgical Pathology. 30: 1175-83. PMID 16931963 DOI: 10.1097/01.Pas.0000213266.84725.D0  1
2006 Campan M, Weisenberger DJ, Laird PW. DNA methylation profiles of female steroid hormone-driven human malignancies Current Topics in Microbiology and Immunology. 310: 141-178. PMID 16909910 DOI: 10.1007/3-540-31181-5_8  1
2006 Marjoram P, Chang J, Laird PW, Siegmund KD. Cluster analysis for DNA methylation profiles having a detection threshold. Bmc Bioinformatics. 7: 361. PMID 16872497 DOI: 10.1186/1471-2105-7-361  1
2006 Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, Kang GH, Widschwendter M, Weener D, Buchanan D, Koh H, Simms L, Barker M, Leggett B, Levine J, ... ... Laird PW, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nature Genetics. 38: 787-93. PMID 16804544 DOI: 10.1038/Ng1834  1
2006 Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, Makrigiorgos GM, Weisenberger DJ, Laird PW, Loda M, Fuchs CS. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. The Journal of Molecular Diagnostics : Jmd. 8: 209-17. PMID 16645207 DOI: 10.2353/Jmoldx.2006.050135  1
2006 Siegmund KD, Levine AJ, Chang J, Laird PW. Modeling exposures for DNA methylation profiles. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 567-72. PMID 16537717 DOI: 10.1158/1055-9965.Epi-05-0717  1
2006 Ehrlich M, Woods CB, Yu MC, Dubeau L, Yang F, Campan M, Weisenberger DJ, Long T, Youn B, Fiala ES, Laird PW. Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene. 25: 2636-45. PMID 16532039 DOI: 10.1038/Sj.Onc.1209145  1
2006 Ogino S, Cantor M, Kawasaki T, Brahmandam M, Kirkner GJ, Weisenberger DJ, Campan M, Laird PW, Loda M, Fuchs CS. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies Gut. 55: 1000-1006. PMID 16407376 DOI: 10.1136/Gut.2005.082933  1
2006 Fiegl H, Millinger S, Goebel G, Müller-Holzner E, Marth C, Laird PW, Widschwendter M. Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Cancer Research. 66: 29-33. PMID 16397211 DOI: 10.1158/0008-5472.Can-05-2508  1
2005 Weisenberger DJ, Campan M, Long TI, Kim M, Woods C, Fiala E, Ehrlich M, Laird PW. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Research. 33: 6823-36. PMID 16326863 DOI: 10.1093/Nar/Gki987  1
2005 Sarter B, Long TI, Tsong WH, Koh WP, Yu MC, Laird PW. Sex differential in methylation patterns of selected genes in Singapore Chinese. Human Genetics. 117: 402-3. PMID 15928902 DOI: 10.1007/S00439-005-1317-9  1
2005 Woodson K, Weisenberger DJ, Campan M, Laird PW, Tangrea J, Johnson LL, Schatzkin A, Lanza E. Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trial. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1219-23. PMID 15894675 DOI: 10.1158/1055-9965.Epi-04-0726  1
2005 Laird PW. Cancer epigenetics. Human Molecular Genetics. 14: R65-76. PMID 15809275 DOI: 10.1093/hmg/ddi113  1
2005 Cote RJ, Laird PW, Datar RH. Promoter hypermethylation: a new therapeutic target emerges in urothelial cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 2879-81. PMID 15753457 DOI: 10.1200/Jco.2005.11.923  1
2005 Tsou JA, Shen LY, Siegmund KD, Long TI, Laird PW, Seneviratne CK, Koss MN, Pass HI, Hagen JA, Laird-Offringa IA. Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. Lung Cancer (Amsterdam, Netherlands). 47: 193-204. PMID 15639718 DOI: 10.1016/J.Lungcan.2004.08.003  1
2005 Theisen J, Peters JH, Fein M, Hughes M, Hagen JA, Demeester SR, Demeester TR, Laird PW. The mutagenic potential of duodenoesophageal reflux. Annals of Surgery. 241: 63-8. PMID 15621992 DOI: 10.1097/01.Sla.0000150072.55037.E3  1
2005 Huang THM, Plass C, Liang G, Laird PW. Epi meets genomics: Technologies for finding and reading the 5th base The Epigenome: Molecular Hide and Seek. 39-64. DOI: 10.1002/3527601511.ch3  1
2004 Kim M, Trinh BN, Long TI, Oghamian S, Laird PW. Dnmt1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells. Nucleic Acids Research. 32: 5742-9. PMID 15509869 DOI: 10.1093/Nar/Gkh912  1
2004 Widschwendter M, Jiang G, Woods C, Müller HM, Fiegl H, Goebel G, Marth C, Müller-Holzner E, Zeimet AG, Laird PW, Ehrlich M. DNA hypomethylation and ovarian cancer biology. Cancer Research. 64: 4472-80. PMID 15231656 DOI: 10.1158/0008-5472.Can-04-0238  1
2004 Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, Laird PW. Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Research. 64: 3807-13. PMID 15172987 DOI: 10.1158/0008-5472.CAN-03-3852  1
2004 Siegmund KD, Laird PW, Laird-Offringa IA. A comparison of cluster analysis methods using DNA methylation data. Bioinformatics (Oxford, England). 20: 1896-904. PMID 15044245 DOI: 10.1093/Bioinformatics/Bth176  1
2004 Pagliarulo V, George B, Beil SJ, Groshen S, Laird PW, Cai J, Willey J, Cote RJ, Datar RH. Sensitivity and reproducibility of standardized-competitive RT-PCR for transcript quantification and its comparison with real time RT-PCR. Molecular Cancer. 3: 5. PMID 14741054 DOI: 10.1186/1476-4598-3-5  1
2003 Uhlmann K, Rohde K, Zeller C, Szymas J, Vogel S, Marczinek K, Thiel G, Nürnberg P, Laird PW. Distinct methylation profiles of glioma subtypes. International Journal of Cancer. 106: 52-9. PMID 12794756 DOI: 10.1002/Ijc.11175  1
2003 Cottrell SE, Laird PW. Sensitive detection of DNA methylation. Annals of the New York Academy of Sciences. 983: 120-30. PMID 12724217 DOI: 10.1111/J.1749-6632.2003.Tb05967.X  1
2003 Laird PW. The power and the promise of DNA methylation markers. Nature Reviews. Cancer. 3: 253-66. PMID 12671664 DOI: 10.1038/Nrc1045  1
2003 Aparicio A, Eads CA, Leong LA, Laird PW, Newman EM, Synold TW, Baker SD, Zhao M, Weber JS. Phase I trial of continuous infusion 5-aza-2'-deoxycytidine. Cancer Chemotherapy and Pharmacology. 51: 231-9. PMID 12655442 DOI: 10.1007/S00280-002-0563-Y  1
2002 Tsien F, Fiala ES, Youn B, Long TI, Laird PW, Weissbecker K, Ehrlich M. Prolonged culture of normal chorionic villus cells yields ICF syndrome-like chromatin decondensation and rearrangements Cytogenetic and Genome Research. 98: 13-21. PMID 12584436 DOI: 10.1159/000068543  1
2002 Tsao JL, Dudley S, Kwok B, Nickel AE, Laird PW, Siegmund KD, Liskay RM, Shibata D. Diet, cancer and aging in DNA mismatch repair deficient mice. Carcinogenesis. 23: 1807-10. PMID 12419828 DOI: 10.1093/Carcin/23.11.1807  1
2002 Ehrlich M, Jiang G, Fiala E, Dome JS, Yu MC, Long TI, Youn B, Sohn OS, Widschwendter M, Tomlinson GE, Chintagumpala M, Champagne M, Parham D, Liang G, Malik K, ... Laird PW, et al. Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene. 21: 6694-702. PMID 12242669 DOI: 10.1038/Sj.Onc.1205890  1
2002 Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW. Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels. Human Genetics. 111: 299-302. PMID 12215845 DOI: 10.1007/S00439-002-0779-2  1
2002 Siegmund KD, Laird PW. Analysis of complex methylation data. Methods (San Diego, Calif.). 27: 170-8. PMID 12095277 DOI: 10.1016/S1046-2023(02)00071-3  1
2002 Eads CA, Laird PW. Combined bisulfite restriction analysis (COBRA). Methods in Molecular Biology (Clifton, N.J.). 200: 71-85. PMID 11951656 DOI: 10.1385/1-59259-182-5:071  1
2002 Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW. DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair. Molecular and Cellular Biology. 22: 2906-17. PMID 11940649 DOI: 10.1128/Mcb.22.9.2906-2917.2002  1
2002 Müller-Ehmsen J, Peterson KL, Kedes L, Whittaker P, Dow JS, Long TI, Laird PW, Kloner RA. Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function. Circulation. 105: 1720-6. PMID 11940553 DOI: 10.1161/01.Cir.0000013782.76324.92  1
2002 Virmani AK, Tsou JA, Siegmund KD, Shen LY, Long TI, Laird PW, Gazdar AF, Laird-Offringa IA. Hierarchical clustering of lung cancer cell lines using DNA methylation markers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 11: 291-7. PMID 11895880  1
2002 Eads CA, Nickel AE, Laird PW. Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice. Cancer Research. 62: 1296-9. PMID 11888894  1
2002 Müller-Ehmsen J, Whittaker P, Kloner RA, Dow JS, Sakoda T, Long TI, Laird PW, Kedes L. Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. Journal of Molecular and Cellular Cardiology. 34: 107-16. PMID 11851351 DOI: 10.1006/Jmcc.2001.1491  1
2002 Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, Laird PW, Jones PA. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Molecular and Cellular Biology. 22: 480-91. PMID 11756544 DOI: 10.1128/Mcb.22.2.480-491.2002  1
2001 Trinh BN, Long TI, Laird PW. DNA methylation analysis by MethyLight technology. Methods (San Diego, Calif.). 25: 456-62. PMID 11846615 DOI: 10.1006/Meth.2001.1268  1
2001 Chan MF, van Amerongen R, Nijjar T, Cuppen E, Jones PA, Laird PW. Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells. Molecular and Cellular Biology. 21: 7587-600. PMID 11604495 DOI: 10.1128/Mcb.21.22.7587-7600.2001  1
2001 Markl ID, Cheng J, Liang G, Shibata D, Laird PW, Jones PA. Global and gene-specific epigenetic patterns in human bladder cancer genomes are relatively stable in vivo and in vitro over time. Cancer Research. 61: 5875-84. PMID 11479229  1
2001 Xiong Z, Wu AH, Bender CM, Tsao JL, Blake C, Shibata D, Jones PA, Yu MC, Ross RK, Laird PW. Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 10: 799-803. PMID 11440966  1
2001 Wajed SA, Laird PW, DeMeester TR. DNA methylation: An alternative pathway to cancer Annals of Surgery. 234: 10-20. PMID 11420478 DOI: 10.1097/00000658-200107000-00003  1
2001 Eads CA, Lord RV, Wickramasinghe K, Long TI, Kurumboor SK, Bernstein L, Peters JH, DeMeester SR, DeMeester TR, Skinner KA, Laird PW. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Research. 61: 3410-8. PMID 11309301  1
2000 Kawakami K, Brabender J, Lord RV, Groshen S, Greenwald BD, Krasna MJ, Yin J, Fleisher AS, Abraham JM, Beer DG, Sidransky D, Huss HT, Demeester TR, Eads C, Laird PW, et al. Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. Journal of the National Cancer Institute. 92: 1805-11. PMID 11078757 DOI: 10.1093/Jnci/92.22.1805  1
2000 Eads CA, Lord RV, Kurumboor SK, Wickramasinghe K, Skinner ML, Long TI, Peters JH, DeMeester TR, Danenberg KD, Danenberg PV, Laird PW, Skinner KA. Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma. Cancer Research. 60: 5021-6. PMID 11016622  1
2000 Laird PW. Mouse models in DNA-methylation research Current Topics in Microbiology and Immunology. 249: 119-134. PMID 10802942  1
2000 Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, Danenberg PV, Laird PW. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Research. 28: E32. PMID 10734209 DOI: 10.1093/Nar/28.8.E32  1
2000 Pao MM, Liang G, Tsai YC, Xiong Z, Laird PW, Jones PA. DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines. Oncogene. 19: 943-52. PMID 10702803 DOI: 10.1038/Sj.Onc.1203414  1
1999 Eads CA, Danenberg KD, Kawakami K, Saltz LB, Danenberg PV, Laird PW. CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Research. 59: 2302-6. PMID 10344733  1
1999 Fein M, Peters JH, Baril N, McGarvey M, Chandrasoma P, Shibata D, Laird PW, Skinner KA. Loss of function of Trp53, but not Apc, leads to the development of esophageal adenocarcinoma in mice with jejunoesophageal reflux. The Journal of Surgical Research. 83: 48-55. PMID 10210642 DOI: 10.1006/Jsre.1998.5559  1
1999 Jones PA, Laird PW. Cancer epigenetics comes of age. Nature Genetics. 21: 163-7. PMID 9988266 DOI: 10.1038/5947  1
1997 Laird PW. Oncogenic mechanisms mediated by DNA methylation Molecular Medicine Today. 3: 223-229. PMID 9176885 DOI: 10.1016/S1357-4310(97)01019-8  1
1997 Xiong Z, Laird PW. COBRA: A sensitive and quantitative DNA methylation assay Nucleic Acids Research. 25: 2532-2534. PMID 9171110 DOI: 10.1093/Nar/25.12.2532  1
1997 Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 94: 4681-5. PMID 9114051 DOI: 10.1073/Pnas.94.9.4681  1
1996 Laird PW, Jaenisch R. The role of DNA methylation in cancer genetics and epigenetics Annual Review of Genetics. 30: 441-464. PMID 8982461 DOI: 10.1146/Annurev.Genet.30.1.441  1
1996 Tucker KL, Beard C, Dausmann J, Jackson-Grusby L, Laird PW, Lei H, Li E, Jaenisch R. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes & Development. 10: 1008-20. PMID 8608936 DOI: 10.1101/Gad.10.8.1008  1
1995 Johnson KA, Lerner CP, Di Lacio LC, Laird PW, Sharpe AH, Simpson EM. Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections Nucleic Acids Research. 23: 1273-1275. PMID 7739908 DOI: 10.1093/Nar/23.7.1273  1
1995 Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R. Suppression of intestinal neoplasia by DNA hypomethylation. Cell. 81: 197-205. PMID 7537636 DOI: 10.1016/0092-8674(95)90329-1  1
1994 Laird PW, Jaenisch R. DNA methylation and cancer Human Molecular Genetics. 3: 1487-1495. PMID 7849743 DOI: 10.1093/Hmg/3.Suppl_1.1487  1
1994 Berns A, van der Lugt N, Alkema M, van Lohuizen M, Domen J, Acton D, Allen J, Laird PW, Jonkers J. Mouse model systems to study multistep tumorigenesis. Cold Spring Harbor Symposia On Quantitative Biology. 59: 435-47. PMID 7587098 DOI: 10.1101/Sqb.1994.059.01.049  1
1993 Domen J, Van der Lugt NMT, Laird PW, Saris CJM, Berns A. Analysis of Pim-1 function in mutant mice Leukemia. 7: S108-S112. PMID 8361211  1
1993 Domen J, van der Lugt NM, Acton D, Laird PW, Linders K, Berns A. Pim-1 levels determine the size of early B lymphoid compartments in bone marrow. The Journal of Experimental Medicine. 178: 1665-73. PMID 8228813 DOI: 10.1084/Jem.178.5.1665  1
1993 Domen J, Van Der Lugt NMT, Laird PW, Saris CJM, Clarke AR, Hooper ML, Berns A. Impaired interleukin-3 response in Pim-1-deficient bone marrow-derived mast cells Blood. 82: 1445-1452. PMID 7689870 DOI: 10.1182/Blood.V82.5.1445.1445  1
1991 Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, Berns A. Simplified mammalian DNA isolation procedure Nucleic Acids Research. 19: 4293. PMID 1870982 DOI: 10.1093/Nar/19.15.4293  1
1991 van der Lugt N, Maandag ER, Riele Ht, Laird PW, Berns A. A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor δ-chain-encoding gene Gene. 105: 263-267. PMID 1834524 DOI: 10.1016/0378-1119(91)90161-4  1
1989 Laird PW. Trans splicing in trypanosomes - archaism or adaptation? Trends in Genetics. 5: 204-208. PMID 2675423 DOI: 10.1016/0168-9525(89)90082-6  1
1987 Laird PW, Asbroek ALMat, Borst P. Controlled turnover and 3′ trimming of the trans splicing precursor of Trypanosoma brucei Nucleic Acids Research. 15: 10087-10103. PMID 3697089 DOI: 10.1093/Nar/15.24.10087  1
1987 Gibson WC, White TC, Laird PW, Borst P. Stable introduction of exogenous DNA into Trypanosoma brucei. The Embo Journal. 6: 2457-61. PMID 3665883 DOI: 10.1002/J.1460-2075.1987.Tb02525.X  1
1987 Imboden MA, Laird PW, Affolter M, Seebeck T. Transcription of the intergenic regions of the tubulin gene cluster of Trypanosoma brucei: Evidence for a polyclstronic transcription unit in a eukaryote Nucleic Acids Research. 15: 7357-7368. PMID 3658696 DOI: 10.1093/Nar/15.18.7357  1
1987 Laird PW, Zomerdijk JC, de Korte D, Borst P. In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei Embo Journal. 6: 1055-1062. PMID 3595556 DOI: 10.1002/J.1460-2075.1987.Tb04858.X  1
1985 Laird PW, Kooter JM, Loosbroek N, Borst P. Mature mRNAs of Trypanosoma brucei possess a 5' cap acquired by discontinuous RNA synthesis. Nucleic Acids Research. 13: 4253-66. PMID 2409534 DOI: 10.1093/Nar/13.12.4253  0.8
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