Zhen Chen, Ph.D. - Publications

Affiliations: 
2001 University of Connecticut, Storrs, CT, United States 
Area:
Statistics

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Duh PD, Chen ZT, Lee SW, Lin TP, Wang YT, Yen WJ, Kuo LF, Chu HL. Antiproliferative activity and apoptosis induction of Eucalyptus Citriodora resin and its major bioactive compound in melanoma B16F10 cells. Journal of Agricultural and Food Chemistry. 60: 7866-72. PMID 22838509 DOI: 10.1021/Jf301068Z  0.423
2005 Nantermet PG, Burgey CS, Robinson KA, Pellicore JM, Newton CL, Deng JZ, Selnick HG, Lewis SD, Lucas BJ, Krueger JA, Miller-Stein C, White RB, Wong B, McMasters DR, Wallace AA, ... ... Chen Z, et al. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold. Bioorganic & Medicinal Chemistry Letters. 15: 2771-5. PMID 15911253 DOI: 10.1016/j.bmcl.2005.03.110  0.476
2004 Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, et al. Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. Journal of Medicinal Chemistry. 47: 6117-9. PMID 15566281 DOI: 10.1021/jm049388p  0.486
2004 Sardana V, Xu B, Zugay-Murphy J, Chen Z, Sardana M, Darke PL, Munshi S, Kuo LC. A general procedure for the purification of human beta-secretase expressed in Escherichia coli. Protein Expression and Purification. 34: 190-6. PMID 15003250 DOI: 10.1016/j.pep.2003.12.014  0.469
2004 Kuo L, Chen Z. A State Duration Model for Brand Choice and Inter-Purchase Time Journal of Data Science. 2: 125-147. DOI: 10.6339/Jds.2004.02(2).138  0.471
2003 Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, ... ... Chen Z, et al. Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides. Bioorganic & Medicinal Chemistry Letters. 13: 1353-7. PMID 12657281 DOI: 10.1016/S0960-894X(03)00099-4  0.479
2003 Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, ... ... Chen Z, et al. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. Journal of Medicinal Chemistry. 46: 461-73. PMID 12570369 DOI: 10.1021/jm020311f  0.469
2001 Chen Z, Kuo L. A note on the estimation of the multinomial logit model with random effects American Statistician. 55: 89-95. DOI: 10.1198/000313001750358545  0.47
2000 Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC. An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease. Acta Crystallographica. Section D, Biological Crystallography. 56: 381-8. PMID 10739910  0.515
2000 Chen Z, Yan Y, Munshi S, Li Y, Zugay-Murphy J, Xu B, Witmer M, Felock P, Wolfe A, Sardana V, Emini EA, Hazuda D, Kuo LC. X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform. Journal of Molecular Biology. 296: 521-33. PMID 10669606 DOI: 10.1006/jmbi.1999.3451  0.473
1999 Li Y, Yan Y, Zugay-Murphy J, Xu B, Cole JL, Witmer M, Felock P, Wolfe A, Hazuda D, Sardana MK, Chen Z, Kuo LC, Sardana VV. Purification, solution properties and crystallization of SIV integrase containing a continuous core and C-terminal domain. Acta Crystallographica. Section D, Biological Crystallography. 55: 1906-10. PMID 10531491 DOI: 10.1107/S0907444999009610  0.478
1998 Munshi S, Chen Z, Li Y, Olsen DB, Fraley ME, Hungate RW, Kuo LC. Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme. Acta Crystallographica. Section D, Biological Crystallography. 54: 1053-60. PMID 9757136  0.502
1998 Yan Y, Li Y, Munshi S, Sardana V, Cole JL, Sardana M, Steinkuehler C, Tomei L, De Francesco R, Kuo LC, Chen Z. Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 A resolution structure in a hexagonal crystal form. Protein Science : a Publication of the Protein Society. 7: 837-47. PMID 9568891 DOI: 10.1002/pro.5560070402  0.488
1997 Smith AB, Hirschmann R, Pasternak A, Yao W, Sprengeler PA, Holloway MK, Kuo LC, Chen Z, Darke PL, Schleif WA. An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex. Journal of Medicinal Chemistry. 40: 2440-4. PMID 9258349 DOI: 10.1021/jm970195u  0.487
1997 Tucker TJ, Lumma WC, Mulichak AM, Chen Z, Naylor-Olsen AM, Lewis SD, Lucas R, Freidinger RM, Kuo LC. Design of highly potent noncovalent thrombin inhibitors that utilize a novel lipophilic binding pocket in the thrombin active site. Journal of Medicinal Chemistry. 40: 830-2. PMID 9083470 DOI: 10.1021/jm960762y  0.466
1995 Palmer GA, Kuo L, Chen Z, Faaberg KS, Plagemann PG. Sequence of the genome of lactate dehydrogenase-elevating virus: heterogenicity between strains P and C. Virology. 209: 637-42. PMID 7778295 DOI: 10.1006/Viro.1995.1296  0.457
1995 Chen Z, Li Y, Schock HB, Hall D, Chen E, Kuo LC. Three-dimensional structure of a mutant HIV-1 protease displaying cross-resistance to all protease inhibitors in clinical trials. The Journal of Biological Chemistry. 270: 21433-6. PMID 7665551  0.513
1994 Chen Z, Li Y, Chen E, Hall DL, Darke PL, Culberson C, Shafer JA, Kuo LC. Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases. The Journal of Biological Chemistry. 269: 26344-8. PMID 7929352  0.501
1993 Chen Z, Kuo L, Rowland RR, Even C, Faaberg KS, Plagemann PG. Sequences of 3' end of genome and of 5' end of open reading frame 1a of lactate dehydrogenase-elevating virus and common junction motifs between 5' leader and bodies of seven subgenomic mRNAs. The Journal of General Virology. 74: 643-59. PMID 8385693 DOI: 10.1099/0022-1317-74-4-643  0.448
1992 Kuo L, Chen Z, Rowland RR, Faaberg KS, Plagemann PG. Lactate dehydrogenase-elevating virus (LDV): subgenomic mRNAs, mRNA leader and comparison of 3'-terminal sequences of two LDV isolates. Virus Research. 23: 55-72. PMID 1604932 DOI: 10.1016/0168-1702(92)90067-J  0.455
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