Michael Regnier - Publications

Affiliations: 
Bioengineering University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hock MT, Teitgen AE, McCabe KJ, Hirakis SP, Huber GA, Regnier M, Amaro RE, McCammon JA, McCulloch AD. Multiscale computational modeling of the effects of 2'-deoxy-ATP on cardiac muscle calcium handling. Journal of Applied Physics. 134: 074905. PMID 37601331 DOI: 10.1063/5.0157935  0.302
2023 Kooiker KB, Mohran S, Turner KL, Ma W, Martinson A, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, ... ... Regnier M, et al. Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle. Circulation Research. PMID 37470183 DOI: 10.1161/CIRCRESAHA.123.322629  0.361
2023 Chong JX, Childers MC, Marvin CT, Marcello AJ, Gonorazky H, Hazrati LN, Dowling JJ, Al Amrani F, Alanay Y, Nieto Y, Gabriel MÁM, Aylsworth AS, Buckingham KJ, Shively KM, Sommers O, ... ... Regnier M, et al. Variants in underlie distal arthrogryposis accompanied by congenital heart defects. Hgg Advances. 4: 100213. PMID 37457373 DOI: 10.1016/j.xhgg.2023.100213  0.306
2023 Chakraborty AD, Kooiker K, Kobak KA, Cheng Y, Lee CF, Razumova M, Granzier H H, Regnier M, Rabinovitch PS, Moussavi-Harami F, Chiao YA. Late-life Rapamycin Treatment Enhances Cardiomyocyte Relaxation Kinetics and Reduces Myocardial Stiffness. Biorxiv : the Preprint Server For Biology. PMID 37398078 DOI: 10.1101/2023.06.12.544619  0.313
2023 Chong JX, Childers MC, Marvin CT, Marcello AJ, Gonorazky H, Hazrati LN, Dowling JJ, Amrani FA, Alanay Y, Nieto Y, Marín Gabriel MÁ, Aylsworth AS, Buckingham KJ, Shively KM, Sommers O, ... ... Regnier M, et al. Variants in underlie distal arthrogryposis accompanied by congenital heart defects. Medrxiv : the Preprint Server For Health Sciences. PMID 36945405 DOI: 10.1101/2023.03.07.23286862  0.307
2023 Ma W, You S, Regnier M, McCammon JA. Integrating comparative modeling and accelerated simulations reveals conformational and energetic basis of actomyosin force generation. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215836120. PMID 36802417 DOI: 10.1073/pnas.2215836120  0.33
2023 Kooiker KB, Mohran S, Turner KL, Ma W, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Martinson A, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, ... ... Regnier M, et al. Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle. Biorxiv : the Preprint Server For Biology. PMID 36778318 DOI: 10.1101/2023.01.31.526380  0.369
2023 Ma W, McMillen TS, Childers MC, Gong H, Regnier M, Irving T. Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207615120. PMID 36696446 DOI: 10.1073/pnas.2207615120  0.309
2022 Pioner JM, Santini L, Palandri C, Langione M, Grandinetti B, Querceto S, Martella D, Mazzantini C, Scellini B, Giammarino L, Lupi F, Mazzarotto F, Gowran A, Rovina D, Santoro R, ... ... Regnier M, et al. Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency. Frontiers in Physiology. 13: 1030920. PMID 36419836 DOI: 10.3389/fphys.2022.1030920  0.357
2022 Prodanovic M, Geeves MA, Poggesi C, Regnier M, Mijailovich SM. Effect of Myosin Isoforms on Cardiac Muscle Twitch of Mice, Rats and Humans. International Journal of Molecular Sciences. 23. PMID 35163054 DOI: 10.3390/ijms23031135  0.35
2021 Mijailovich SM, Prodanovic M, Poggesi C, Geeves MA, Regnier M. Multiscale modeling of twitch contractions in cardiac trabeculae. The Journal of General Physiology. 153. PMID 33512405 DOI: 10.1085/jgp.202012604  0.367
2020 McCabe KJ, Aboelkassem Y, Teitgen AE, Huber GA, McCammon JA, Regnier M, McCulloch AD. Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere. Archives of Biochemistry and Biophysics. 108582. PMID 32956632 DOI: 10.1016/J.Abb.2020.108582  0.342
2020 Powers JD, Kooiker KB, Mason AB, Teitgen AE, Flint GV, Tardiff JC, Schwartz SD, McCulloch AD, Regnier M, Davis J, Moussavi-Harami F. Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts. Jci Insight. PMID 32931484 DOI: 10.1172/Jci.Insight.142446  0.307
2020 Ma W, Childers M, Murray J, Moussavi-Harami F, Gong H, Weiss R, Daggett V, Irving T, Regnier M. Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2'-deoxy-ATP. The Journal of Physiology. PMID 32818298 DOI: 10.1113/Jp280402  0.319
2020 Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W. Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophysical Journal. PMID 32730789 DOI: 10.1016/J.Bpj.2020.07.006  0.316
2020 Shao D, Kolwicz SC, Wang P, Roe ND, Villet O, Nishi K, Hsu YA, Flint GV, Caudal A, Wang W, Regnier M, Tian R. Increasing Fatty Acid Oxidation Prevents High Fat Diet Induced Cardiomyopathy through Regulating Parkin Mediated Mitophagy. Circulation. PMID 32597196 DOI: 10.1161/Circulationaha.119.043319  0.322
2019 Quarles E, Basisty N, Chiao YA, Merrihew G, Gu H, Sweetwyne MT, Fredrickson J, Nguyen NH, Razumova M, Kooiker K, Moussavi-Harami F, Regnier M, Quarles C, MacCoss M, Rabinovitch PS. Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment. Aging Cell. e13086. PMID 31823466 DOI: 10.1111/Acel.13086  0.332
2019 Zaunbrecher RJ, Abel AN, Beussman K, Leonard A, von Frieling-Salewsky M, Fields PA, Pabon L, Reinecke H, Yang X, Macadangdang J, Kim DH, Linke WA, Sniadecki NJ, Regnier M, Murry CE. Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function. Circulation. PMID 31587567 DOI: 10.1161/Circulationaha.119.039521  0.393
2019 Aboelkassem Y, McCabe KJ, Huber GA, Regnier M, McCammon JA, McCulloch AD. A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics. Biophysical Journal. PMID 31547973 DOI: 10.1016/J.Bpj.2019.08.003  0.322
2019 Pioner JM, Santini L, Palandri C, Martella D, Lupi F, Langione M, Querceto S, Grandinetti B, Balducci V, Benzoni P, Landi S, Barbuti A, Ferrarese Lupi F, Boarino L, Sartiani L, ... ... Regnier M, et al. Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates. International Journal of Molecular Sciences. 20. PMID 31382622 DOI: 10.3390/Ijms20153799  0.31
2019 Bargehr J, Ong LP, Colzani M, Davaapil H, Hofsteen P, Bhandari S, Gambardella L, Le Novère N, Iyer D, Sampaziotis F, Weinberger F, Bertero A, Leonard A, Bernard WG, Martinson A, ... ... Regnier M, et al. Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration. Nature Biotechnology. 37: 895-906. PMID 31375810 DOI: 10.1038/S41587-019-0197-9  0.362
2019 Powers JD, Yuan CC, McCabe KJ, Murray JD, Childers MC, Flint GV, Moussavi-Harami F, Mohran S, Castillo R, Zuzek C, Ma W, Daggett V, McCulloch AD, Irving TC, Regnier M. Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin. Proceedings of the National Academy of Sciences of the United States of America. PMID 31110001 DOI: 10.1073/Pnas.1905028116  0.477
2019 Pioner JM, Guan X, Klaiman JM, Racca AW, Pabon L, Muskheli V, Macadangdang J, Ferrantini C, Hoopmann MR, Moritz RL, Kim DH, Tesi C, Poggesi C, Murry CE, Childers MK, ... ... Regnier M, et al. Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human induced pluripotent stem cells. Cardiovascular Research. PMID 31049579 DOI: 10.1093/Cvr/Cvz109  0.341
2019 Kim MJ, Bible KL, Regnier M, Adams ME, Froehner SC, Whitehead NP. Simvastatin provides long-term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy. Physiological Reports. 7: e14018. PMID 30912308 DOI: 10.14814/Phy2.14018  0.38
2019 Yuan C, Powers JD, McCabe KJ, Murray JD, Saffie M, Romi C, Carla Z, Ma W, McCulloch AD, Irving TC, Regnier M. Enhanced Crossbridge Binding with 2-Deoxy-ATP Results from Increased Electrostatic Interactions between Myosin and Actin in Cardiac Muscle Biophysical Journal. 116: 466a. DOI: 10.1016/J.Bpj.2018.11.2518  0.365
2018 Yang KC, Breitbart A, De Lange WJ, Hofsteen P, Futakuchi-Tsuchida A, Xu J, Schopf C, Razumova MV, Jiao A, Boucek R, Pabon L, Reinecke H, Kim DH, Ralphe JC, Regnier M, et al. Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells. Jacc. Basic to Translational Science. 3: 728-740. PMID 30623132 DOI: 10.1016/J.Jacbts.2018.08.008  0.352
2018 Regnier M. Mechanistic complexity of contractile dysfunction in hypertrophic cardiomyopathy. The Journal of General Physiology. PMID 30037852 DOI: 10.1085/Jgp.201812091  0.33
2018 Powers J, Williams C, Regnier M, Daniel T. A spatially explicit model shows how titin stiffness modulates muscle mechanics and energetics. Integrative and Comparative Biology. PMID 29897447 DOI: 10.1093/Icb/Icy055  0.455
2018 Leonard A, Bertero A, Powers JD, Beussman KM, Bhandari S, Regnier M, Murry CE, Sniadecki NJ. Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues. Journal of Molecular and Cellular Cardiology. PMID 29604261 DOI: 10.1016/J.Yjmcc.2018.03.016  0.424
2018 Mijailovich SM, Nedic D, Stojanovic B, Powers JD, Davis J, Geeves MA, Regnier M. Influence of cTn Ca2+ Binding Properties and Cooperative Mechanisms on Cardiac Muscle Contractile Dynamics Biophysical Journal. 114: 500a. DOI: 10.1016/J.Bpj.2017.11.2737  0.435
2017 Dewan S, McCabe KJ, Regnier M, McCulloch AD. Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype. Frontiers in Physiology. 8: 151. PMID 28352236 DOI: 10.3389/Fphys.2017.00151  0.322
2017 Zieba J, Zhang W, Chong JX, Forlenza KN, Martin JH, Heard K, Grange DK, Butler MG, Kleefstra T, Lachman RS, Nickerson D, Regnier M, Cohn DH, Bamshad M, Krakow D. A postnatal role for embryonic myosin revealed by MYH3 mutations that alter TGFβ signaling and cause autosomal dominant spondylocarpotarsal synostosis. Scientific Reports. 7: 41803. PMID 28205584 DOI: 10.1038/Srep41803  0.311
2017 Nowakowski SG, Regnier M, Daggett V. Molecular mechanisms underlying deoxy-ADP.Pi activation of pre-powerstroke myosin. Protein Science : a Publication of the Protein Society. PMID 28097776 DOI: 10.1002/Pro.3121  0.459
2017 Powers JD, Moussavi-Harami F, Razumova M, Tardiff J, Regnier M. The Frank-Starling Mechansim is Attenuated by a Dilated Cardiomyopathy-Associated Tropomyosin Mutation Biophysical Journal. 112: 120a. DOI: 10.1016/J.Bpj.2016.11.673  0.443
2016 Thomson KS, Odom GL, Murry CE, Mahairas GG, Moussavi-Harami F, Teichman SL, Chen X, Hauschka SD, Chamberlain JS, Regnier M. Translation of Cardiac Myosin Activation with 2-deoxy-ATP to Treat Heart Failure via an Experimental Ribonucleotide Reductase-Based Gene Therapy. Jacc. Basic to Translational Science. 1: 666-679. PMID 28553667 DOI: 10.1016/J.Jacbts.2016.07.006  0.4
2016 Ruan JL, Tulloch NL, Razumova MV, Saiget M, Muskheli V, Pabon L, Reinecke H, Regnier M, Murry CE. Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue. Circulation. PMID 27737958 DOI: 10.1161/Circulationaha.114.014998  0.368
2016 Teichman SL, Thomson KS, Regnier M. Cardiac Myosin Activation with Gene Therapy Produces Sustained Inotropic Effects and May Treat Heart Failure with Reduced Ejection Fraction. Handbook of Experimental Pharmacology. PMID 27590227 DOI: 10.1007/164_2016_31  0.386
2016 Pioner JM, Racca AW, Klaiman JM, Yang KC, Guan X, Pabon L, Muskheli V, Zaunbrecher R, Macadangdang J, Jeong MY, Mack DL, Childers MK, Kim DH, Tesi C, Poggesi C, ... ... Regnier M, et al. Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cell Reports. PMID 27161364 DOI: 10.1016/J.Stemcr.2016.04.006  0.319
2016 Cheng Y, Lindert S, Oxenford L, Tu AY, McCulloch AD, Regnier M. The Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation. The Journal of Physical Chemistry. B. PMID 27150586 DOI: 10.1021/Acs.Jpcb.6B01859  0.436
2016 Dewan S, McCabe KJ, Regnier M, McCulloch AD, Lindert S. Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation - An Integrated Multi-Scale Modeling Study. The Journal of Physical Chemistry. B. PMID 27133568 DOI: 10.1021/Acs.Jpcb.6B01950  0.391
2016 Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, et al. A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy. Cell. PMID 27114035 DOI: 10.1016/J.Cell.2016.04.002  0.357
2016 Roberts MA, Tran D, Coulombe KL, Razumova MV, Regnier M, Murry CE, Zheng Y. Stromal cells in dense collagen promote cardiomyocyte and microvascular patterning in engineered human heart tissue. Tissue Engineering. Part A. PMID 26955856 DOI: 10.1089/Ten.Tea.2015.0482  0.352
2016 Carson D, Hnilova M, Yang X, Nemeth CL, Tsui JH, Smith AS, Jiao A, Regnier M, Murry CE, Tamerler C, Kim DH. Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells. Acs Applied Materials & Interfaces. PMID 26866596 DOI: 10.1021/Acsami.5B11671  0.323
2016 Cheng Y, Regnier M. Cardiac Troponin Structure-Function and the Influence of Hypertrophic Cardiomyopathy Associated Mutations on Modulation of Contractility. Archives of Biochemistry and Biophysics. PMID 26851561 DOI: 10.1016/J.Abb.2016.02.004  0.445
2016 Regnier M, Cheng Y. Finally, We Can Relax: A New Generation of Muscle Models that Incorporate Sarcomere Compliance. Biophysical Journal. 110: 521-2. PMID 26840717 DOI: 10.1016/J.Bpj.2015.12.025  0.417
2016 Cheng Y, Steffen L, Tu A, Razumova MV, Xie L, Oxenford L, McCulloch AD, McCammon JA, Regnier M. HCM Associated Cardiac Troponin I Mutations Alter Cardiac Troponin Function, Contractile Properties and Modulation by PKA Mediated Phosphorylation Biophysical Journal. 110: 465a. DOI: 10.1016/J.Bpj.2015.11.2487  0.338
2015 Cheng Y, Hogarth KA, O'Sullivan ML, Regnier M, Pyle WG. 2-Deoxy-adenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00530.2015. PMID 26497964 DOI: 10.1152/Ajpheart.00530.2015  0.365
2015 Racca AW, Klaiman JM, Pioner JM, Cheng Y, Beck AE, Moussavi-Harami F, Bamshad MJ, Regnier M. Contractile properties of developing human fetal cardiac muscle. The Journal of Physiology. PMID 26460603 DOI: 10.1113/Jp271290  0.445
2015 Cheng Y, Rao V, Tu AY, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M. Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation. The Journal of Biological Chemistry. 290: 27749-66. PMID 26391394 DOI: 10.1074/Jbc.M115.683045  0.474
2015 Kolwicz SC, Odom GL, Nowakowski SG, Moussavi-Harami F, Chen X, Reinecke H, Hauschka SD, Murry CE, Mahairas GG, Regnier M. AAV6-mediated Cardiac Specific Over-expression of Ribonucleotide Reductase Enhances Myocardial Contractility. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26388461 DOI: 10.1038/Mt.2015.176  0.412
2015 Kadota S, Carey J, Reinecke H, Leggett J, Teichman S, Laflamme MA, Murry CE, Regnier M, Mahairas GG. Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure. European Journal of Heart Failure. PMID 25876005 DOI: 10.1002/Ejhf.270  0.374
2015 Ruan JL, Tulloch NL, Saiget M, Paige SL, Razumova MV, Regnier M, Tung KC, Keller G, Pabon L, Reinecke H, Murry CE. Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors. Stem Cells (Dayton, Ohio). 33: 2148-57. PMID 25865043 DOI: 10.1002/Stem.2036  0.386
2015 Racca AW, Beck AE, McMillin MJ, Korte FS, Bamshad MJ, Regnier M. The embryonic myosin R672C mutation that underlies Freeman-Sheldon syndrome impairs cross-bridge detachment and cycling in adult skeletal muscle. Human Molecular Genetics. 24: 3348-58. PMID 25740846 DOI: 10.1093/Hmg/Ddv084  0.43
2015 Lehman W, Medlock G, Li XE, Suphamungmee W, Tu AY, Schmidtmann A, Ujfalusi Z, Fischer S, Moore JR, Geeves MA, Regnier M. Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain. Archives of Biochemistry and Biophysics. 571: 10-5. PMID 25726728 DOI: 10.1016/J.Abb.2015.02.026  0.375
2015 Lindert S, Cheng Y, Kekenes-Huskey P, Regnier M, McCammon JA. Effects of HCM cTnI mutation R145G on troponin structure and modulation by PKA phosphorylation elucidated by molecular dynamics simulations. Biophysical Journal. 108: 395-407. PMID 25606687 DOI: 10.1016/J.Bpj.2014.11.3461  0.43
2015 Moussavi-Harami F, Razumova MV, Racca AW, Cheng Y, Stempien-Otero A, Regnier M. 2-Deoxy adenosine triphosphate improves contraction in human end-stage heart failure. Journal of Molecular and Cellular Cardiology. 79: 256-63. PMID 25498214 DOI: 10.1016/J.Yjmcc.2014.12.002  0.528
2015 Moussavi-Harami F, Razumova MV, Cheng Y, Odom G, Teichman S, Tardiff J, Hauschka SD, Chamberlain JS, Murry CM, Regnier M. 11. Gene Therapy Mediated Increase in dATP Improves Cardiac Performance in Models of Systolic Heart Failure Molecular Therapy. 23: S5. DOI: 10.1016/S1525-0016(16)33615-2  0.375
2015 Pioner JM, Racca AW, Guan X, Pabon L, Jeong MY, Childers CI, Macadangdang J, Muskheli V, Poggesi C, Kim D, Mack DL, Childers MK, Murry CE, Regnier M. Contractile Properties of Myofibrils from hiPSC-Derived Cardiomyocytes of Patients with Duchenne Muscular Dystrophy Biophysical Journal. 108: 295a. DOI: 10.1016/J.Bpj.2014.11.1607  0.423
2015 Pioner JM, Yang K, Pabon L, Racca AW, Jeong MY, Childers CI, Macadangdang J, Tesi C, Poggesi C, Kim D, Murry CE, Regnier M. Cell and Myofibril Contractile Properties of hiPSC-Derived Cardiomyocytes from a Patient with a MYH7 Mutation Associated with Familial Cardiomyopathy Biophysical Journal. 108: 201a. DOI: 10.1016/J.Bpj.2014.11.1110  0.369
2014 Scellini B, Piroddi N, Flint GV, Regnier M, Poggesi C, Tesi C. Impact of tropomyosin isoform composition on fast skeletal muscle thin filament regulation and force development. Journal of Muscle Research and Cell Motility. 36: 11-23. PMID 25380572 DOI: 10.1007/S10974-014-9394-9  0.556
2014 Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophysical Journal. 107: 1675-85. PMID 25296321 DOI: 10.1016/J.Bpj.2014.08.008  0.434
2014 Rao V, Cheng Y, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M. PKA phosphorylation of cardiac troponin I modulates activation and relaxation kinetics of ventricular myofibrils. Biophysical Journal. 107: 1196-204. PMID 25185555 DOI: 10.1016/J.Bpj.2014.07.027  0.54
2014 Macadangdang J, Lee HJ, Carson D, Jiao A, Fugate J, Pabon L, Regnier M, Murry C, Kim DH. Capillary force lithography for cardiac tissue engineering. Journal of Visualized Experiments : Jove. PMID 24962161 DOI: 10.3791/50039  0.368
2014 Lundy SD, Murphy SA, Dupras SK, Dai J, Murry CE, Laflamme MA, Regnier M. Cell-based delivery of dATP via gap junctions enhances cardiac contractility. Journal of Molecular and Cellular Cardiology. 72: 350-9. PMID 24780238 DOI: 10.1016/J.Yjmcc.2014.04.010  0.686
2014 Feest ER, Steven Korte F, Tu AY, Dai J, Razumova MV, Murry CE, Regnier M. Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts. Journal of Molecular and Cellular Cardiology. 72: 219-27. PMID 24690333 DOI: 10.1016/J.Yjmcc.2014.03.015  0.832
2014 Cheng Y, Rao VS, Razumova MV, Tu A, Xie L, Luo Z(, McCammon JA, McCulloch A, Regnier M. The Mechanism of HCM-Related Mutation R21C on the Modulation of C-I Interactions and Contractile Kinetics Biophysical Journal. 106: 726a. DOI: 10.1016/J.Bpj.2013.11.4008  0.326
2014 Racca AW, Beck AE, Bamshad MJ, Regnier M. Differences in Activation and Relaxation Kinetics of Human Fetal Skeletal and Cardiac Myofibrils Biophysical Journal. 106: 562a. DOI: 10.1016/J.Bpj.2013.11.3121  0.425
2014 Gay E, Nowakowski SG, Kolwicz SC, Odom GL, Flint GV, Stuppard R, Gu H, Chamberlain JS, Raftery D, Tian R, Marcinek DJ, Regnier M. AAV6-Mediated Overexpression of Ribonucleotide Reductase (R1R2) Enhances 2-Deoxy-ATP Concentration in Vivo and Improves Cardiac Function Biophysical Journal. 106: 345a. DOI: 10.1016/J.Bpj.2013.11.1970  0.323
2014 Regnier M, Cheng Y, Kekenes-Huskey P, Lindert S, McCulloch A. Experimental and Computational Approaches to Study Myofilament Structure-Function in Normal and Diseased Muscle Biophysical Journal. 106: 221a. DOI: 10.1016/J.Bpj.2013.11.1292  0.48
2013 Rodriguez AG, Rodriguez ML, Han SJ, Sniadecki NJ, Regnier M. Enhanced contractility with 2-deoxy-ATP and EMD 57033 is correlated with reduced myofibril structure and twitch power in neonatal cardiomyocytes. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1366-73. PMID 24056444 DOI: 10.1039/C3Ib40135A  0.681
2013 Williams CD, Salcedo MK, Irving TC, Regnier M, Daniel TL. The length-tension curve in muscle depends on lattice spacing. Proceedings. Biological Sciences / the Royal Society. 280: 20130697. PMID 23843386 DOI: 10.1098/Rspb.2013.0697  0.445
2013 Racca AW, Beck AE, Rao VS, Flint GV, Lundy SD, Born DE, Bamshad MJ, Regnier M. Contractility and kinetics of human fetal and human adult skeletal muscle. The Journal of Physiology. 591: 3049-61. PMID 23629510 DOI: 10.1113/Jphysiol.2013.252650  0.682
2013 Nowakowski SG, Kolwicz SC, Korte FS, Luo Z, Robinson-Hamm JN, Page JL, Brozovich F, Weiss RS, Tian R, Murry CE, Regnier M. Transgenic overexpression of ribonucleotide reductase improves cardiac performance. Proceedings of the National Academy of Sciences of the United States of America. 110: 6187-92. PMID 23530224 DOI: 10.1073/Pnas.1220693110  0.448
2013 Lundy SD, Zhu WZ, Regnier M, Laflamme MA. Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Stem Cells and Development. 22: 1991-2002. PMID 23461462 DOI: 10.1089/Scd.2012.0490  0.64
2013 Wang D, McCully ME, Luo Z, McMichael J, Tu AY, Daggett V, Regnier M. Structural and functional consequences of cardiac troponin C L57Q and I61Q Ca(2+)-desensitizing variants. Archives of Biochemistry and Biophysics. 535: 68-75. PMID 23454346 DOI: 10.1016/J.Abb.2013.02.006  0.494
2013 Rao VS, Korte FS, Razumova MV, Feest ER, Hsu H, Irving TC, Regnier M, Martyn DA. N-terminal phosphorylation of cardiac troponin-I reduces length-dependent calcium sensitivity of contraction in cardiac muscle. The Journal of Physiology. 591: 475-90. PMID 23129792 DOI: 10.1113/Jphysiol.2012.241604  0.82
2013 Racca AW, Beck AE, Rao V, Bamshad M, Regnier M. Contractile Properties of Human Fetal Skeletal Myofibrils Biophysical Journal. 104: 483a. DOI: 10.1016/J.Bpj.2012.11.2666  0.419
2013 Rao VS, Lindert S, Wang DD, Kekenes-Huskey P, Cheng Y, McCammon JA, McCulloch A, Arzberger P, Regnier M. Mechanisms of Altered Cardiac Myofibril Relaxation Caused by the Cardiac Troponin-I R145G Mutation Biophysical Journal. 104: 311a. DOI: 10.1016/J.Bpj.2012.11.1728  0.336
2013 Nowakowski SG, Adamek N, Geeves MA, Gay E, Kolwicz SC, Murry CE, Daggett V, Regnier M. 2-deoxy-ATP Alters Myosin Structure to Enhance Cross-Bridge Cycling and Improve Cardiac Function Biophysical Journal. 104: 17a. DOI: 10.1016/J.Bpj.2012.11.125  0.358
2012 Williams CD, Regnier M, Daniel TL. Elastic energy storage and radial forces in the myofilament lattice depend on sarcomere length. Plos Computational Biology. 8: e1002770. PMID 23166482 DOI: 10.1371/Journal.Pcbi.1002770  0.414
2012 Korte FS, Feest ER, Razumova MV, Tu AY, Regnier M. Enhanced Ca2+ binding of cardiac troponin reduces sarcomere length dependence of contractile activation independently of strong crossbridges. American Journal of Physiology. Heart and Circulatory Physiology. 303: H863-70. PMID 22865385 DOI: 10.1152/Ajpheart.00395.2012  0.838
2012 Wang D, Robertson IM, Li MX, McCully ME, Crane ML, Luo Z, Tu AY, Daggett V, Sykes BD, Regnier M. Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation. Biochemistry. 51: 4473-87. PMID 22591429 DOI: 10.1021/Bi3003007  0.528
2012 Tanner BC, Daniel TL, Regnier M. Filament compliance influences cooperative activation of thin filaments and the dynamics of force production in skeletal muscle. Plos Computational Biology. 8: e1002506. PMID 22589710 DOI: 10.1371/Journal.Pcbi.1002506  0.784
2012 Liu Y, Korte FS, Moussavi-Harami F, Yu M, Razumova M, Regnier M, Chin MT. Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1860-70. PMID 22408025 DOI: 10.1152/Ajpheart.00702.2011  0.375
2012 Korte FS, Odom GL, Dai J, Kolwicz SC, Robinson-Hamm JN, Tian R, Hauschka SD, Chamberlain JS, Weiss RS, Murry CE, Regnier M. Broad Transgenic, and Cardiac-Specific Viral Mediated, Over-Expression of Ribonucleotide Reductase Increases In Vivo Cardiac Contractility Biophysical Journal. 102: 615a. DOI: 10.1016/J.Bpj.2011.11.3351  0.391
2011 Rodriguez AG, Han SJ, Regnier M, Sniadecki NJ. Substrate stiffness increases twitch power of neonatal cardiomyocytes in correlation with changes in myofibril structure and intracellular calcium. Biophysical Journal. 101: 2455-64. PMID 22098744 DOI: 10.1016/J.Bpj.2011.09.057  0.659
2011 Korte FS, Dai J, Buckley K, Feest ER, Adamek N, Geeves MA, Murry CE, Regnier M. Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. Journal of Molecular and Cellular Cardiology. 51: 894-901. PMID 21925507 DOI: 10.1016/J.Yjmcc.2011.08.026  0.841
2011 Tulloch NL, Muskheli V, Razumova MV, Korte FS, Regnier M, Hauch KD, Pabon L, Reinecke H, Murry CE. Growth of engineered human myocardium with mechanical loading and vascular coculture. Circulation Research. 109: 47-59. PMID 21597009 DOI: 10.1161/Circresaha.110.237206  0.367
2011 Kreutziger KL, Piroddi N, McMichael JT, Tesi C, Poggesi C, Regnier M. Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle. Journal of Molecular and Cellular Cardiology. 50: 165-74. PMID 21035455 DOI: 10.1016/J.Yjmcc.2010.10.025  0.805
2011 Martyn D, Rao V, Regnier M. Fluorescence Measurements Using Rhodamine-Labeled cTnC Mutants Indicate Little Cooperative Interaction Between Cardiac Thin Filament Regulatory Units Biophysical Journal. 100: 453a. DOI: 10.1016/J.Bpj.2010.12.2670  0.479
2011 Turtle CW, Korte FS, Razumova MV, Regnier M. Reducing Thin Filament Ca2+ Affinity with a cTnC Variant (L57Q) Reduces Force but Enhances Cross-Bridge Dependence of Cooperative Activation in Demembranated Rat Trabeculae Biophysical Journal. 100: 453a. DOI: 10.1016/j.bpj.2010.12.2669  0.421
2011 Martyn DA, Korte S, Razumova M, Feest E, Irving T, Regnier M. Both PKA Treatment and Cardiac Troponin-I N-Terminal Phosphorylation Alone Decrease Ca-Sensitivity and Eliminate Length-Dependent Activation in Skinned Cardiac Muscle Biophysical Journal. 100: 453a. DOI: 10.1016/J.Bpj.2010.12.2668  0.821
2011 Wang D, Korte FS, McMichael J, Luo CZ, Tu A, McCully ME, Daggett V, Regnier M. Mutations that Alter cTnC Ca2+ Binding Affect Interactions with cTnI and Cardiomyocyte Contraction Biophysical Journal. 100: 360a. DOI: 10.1016/J.Bpj.2010.12.2159  0.416
2010 Williams CD, Regnier M, Daniel TL. Axial and radial forces of cross-bridges depend on lattice spacing. Plos Computational Biology. 6: e1001018. PMID 21152002 DOI: 10.1371/Journal.Pcbi.1001018  0.406
2010 Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, ... Regnier M, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/Circulationaha.110.950089  0.315
2010 Wang D, McCully ME, Luo Z, Tu A, Daggett V, Regnier M. Effects of Cardiac TnC Variants on cTnC-cTnI Interaction;Solution and Molecular Dynamics Simulation Studies Biophysical Journal. 98: 149a-150a. DOI: 10.1016/J.Bpj.2009.12.805  0.424
2010 Robertson IM, Li MX, Boyko RF, Crane ML, Regnier M, Sykes BD. The Perturbation of the Open-Closed Transition of Troponin C by the Mutation L48Q Leads to an Enhanced Troponin I Affinity Biophysical Journal. 98: 149a. DOI: 10.1016/j.bpj.2009.12.804  0.406
2010 Rodriguez AG, Han S, Regnier M, Sniadecki N. The Effect of Stiffness and Beta-Adrenergic Stimulation on Neonatal Cardiomyocyte Calcium-Mediated Contractile Force Dynamics Biophysical Journal. 98: 757a. DOI: 10.1016/J.Bpj.2009.12.4155  0.651
2010 Lundy SD, Bloemink MJ, Lynn SC, Geeves MA, Laflamme MA, Regnier M. Mechanical and Biochemical Characteristics of Human Stem Cell-Derived Cardiomyocytes Biophysical Journal. 98: 718a. DOI: 10.1016/J.Bpj.2009.12.3935  0.634
2010 Piroddi N, Kreutziger KL, Scellini B, Lundy S, Ferrantini C, Tesi C, Regnier M, Poggesi C. Effect of Troponin Ca2+ Binding Properties on the Kinetics of Myofibril Force Initiation and Relaxation Biophysical Journal. 98: 415a. DOI: 10.1016/J.Bpj.2009.12.2242  0.82
2010 Korte FS, Feest ER, Razumova MV, Regnier M. Sarcomere Length Dependent Contractile Activation is Reduced in Rat Trabeculae Exchanged with cTn Containing the L48Q cTnC Variant Independently of Strong Binding Cross-Bridges Biophysical Journal. 98: 356a. DOI: 10.1016/J.Bpj.2009.12.1922  0.841
2010 Korte FS, Razumova MV, Feest ER, Wang D, Regnier M. PKA Phosphorylation Has No Effect on the Force-PCA Relationship or Length Dependent Activation Following L48Q cTNC-Tn Exchange in Rat Demembranated Trabeculae Biophysical Journal. 98: 6a. DOI: 10.1016/J.Bpj.2009.12.039  0.83
2009 Stevens KR, Kreutziger KL, Dupras SK, Korte FS, Regnier M, Muskheli V, Nourse MB, Bendixen K, Reinecke H, Murry CE. Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proceedings of the National Academy of Sciences of the United States of America. 106: 16568-73. PMID 19805339 DOI: 10.1073/Pnas.0908381106  0.713
2009 Moreno-Gonzalez A, Korte FS, Dai J, Chen K, Ho B, Reinecke H, Murry CE, Regnier M. Cell therapy enhances function of remote non-infarcted myocardium. Journal of Molecular and Cellular Cardiology. 47: 603-13. PMID 19683533 DOI: 10.1016/J.Yjmcc.2009.07.030  0.801
2009 Smith L, Tainter C, Regnier M, Martyn DA. Cooperative cross-bridge activation of thin filaments contributes to the Frank-Starling mechanism in cardiac muscle Biophysical Journal. 96: 3692-3702. PMID 19413974 DOI: 10.1016/J.Bpj.2009.02.018  0.6
2009 Korte FS, Regnier M, Gillis TE. Influence Of Acidic pH On The Rate Of Force Development In Cardiac Muscle Biophysical Journal. 96: 621a. DOI: 10.1016/J.Bpj.2008.12.3282  0.422
2009 Rodriguez AG, Han S, Regnier M, Sniadecki N. Microfabricated Post Array Detectors to assess cardiomyocyte forces induced on their environment via focal adhesions Biophysical Journal. 96: 497a-498a. DOI: 10.1016/J.Bpj.2008.12.2569  0.648
2009 Korte FS, Wang D, Regnier M. Sarcomere Length Dependence Of The Force-pCa Relationship In Cardiac Muscle Is Influenced By Properties Of Thin Filament Regulatory Units Biophysical Journal. 96: 223a-224a. DOI: 10.1016/j.bpj.2008.12.1938  0.379
2009 Feest ER, Tu A, Luo C, Nowakowski SG, Regnier M. Effect of Varying Mutant Troponin C Content on Contractile Properties of Striated Muscle Biophysical Journal. 96: 228a. DOI: 10.1016/J.Bpj.2008.12.1120  0.817
2008 Razumova MV, Bezold KL, Tu AY, Regnier M, Harris SP. Contribution of the myosin binding protein C motif to functional effects in permeabilized rat trabeculae. The Journal of General Physiology. 132: 575-85. PMID 18955596 DOI: 10.1085/Jgp.200810013  0.442
2008 Kreutziger KL, Piroddi N, Scellini B, Tesi C, Poggesi C, Regnier M. Thin filament Ca2+ binding properties and regulatory unit interactions alter kinetics of tension development and relaxation in rabbit skeletal muscle. The Journal of Physiology. 586: 3683-700. PMID 18535094 DOI: 10.1113/Jphysiol.2008.152181  0.764
2008 Tanner BC, Regnier M, Daniel TL. A spatially explicit model of muscle contraction explains a relationship between activation phase, power and ATP utilization in insect flight. The Journal of Experimental Biology. 211: 180-6. PMID 18165245 DOI: 10.1242/Jeb.013466  0.703
2007 Tanner BC, Daniel TL, Regnier M. Sarcomere lattice geometry influences cooperative myosin binding in muscle. Plos Computational Biology. 3: e115. PMID 17630823 DOI: 10.1371/Journal.Pcbi.0030115  0.756
2007 Kreutziger KL, Gillis TE, Davis JP, Tikunova SB, Regnier M. Influence of enhanced troponin C Ca2+-binding affinity on cooperative thin filament activation in rabbit skeletal muscle. The Journal of Physiology. 583: 337-50. PMID 17584846 DOI: 10.1113/Jphysiol.2007.135426  0.804
2007 Martyn DA, Smith L, Kreutziger KL, Xu S, Yu LC, Regnier M. The effects of force inhibition by sodium vanadate on cross-bridge binding, force redevelopment, and Ca2+ activation in cardiac muscle. Biophysical Journal. 92: 4379-90. PMID 17400698 DOI: 10.1529/Biophysj.106.096768  0.789
2007 Shaffer JF, Razumova MV, Tu AY, Regnier M, Harris SP. Myosin S2 is not required for effects of myosin binding protein-C on motility. Febs Letters. 581: 1501-4. PMID 17376443 DOI: 10.1016/J.Febslet.2007.03.007  0.333
2007 Gillis TE, Martyn DA, Rivera AJ, Regnier M. Investigation of thin filament near-neighbour regulatory unit interactions during force development in skinned cardiac and skeletal muscle. The Journal of Physiology. 580: 561-76. PMID 17317743 DOI: 10.1113/Jphysiol.2007.128975  0.623
2007 Moreno-Gonzalez A, Gillis TE, Rivera AJ, Chase PB, Martyn DA, Regnier M. Thin-filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres. The Journal of Physiology. 579: 313-26. PMID 17204497 DOI: 10.1113/Jphysiol.2006.124164  0.82
2007 Kataoka A, Tanner BCW, Macpherson JM, Xu X, Wang Q, Regnier M, Daniel TL, Chase PB. Spatially explicit, nano-mechanical models of the muscle half-sarcomere: Implications for biomechanical tuning in atrophy and fatigue Acta Astronautica. 60: 111-118. DOI: 10.1016/J.Actaastro.2006.07.008  0.547
2006 Razumova MV, Shaffer JF, Tu AY, Flint GV, Regnier M, Harris SP. Effects of the N-terminal domains of myosin binding protein-C in an in vitro motility assay: Evidence for long-lived cross-bridges. The Journal of Biological Chemistry. 281: 35846-54. PMID 17012744 DOI: 10.1074/Jbc.M606949200  0.398
2006 Bell MG, Lankford EB, Gonye GE, Ellis-Davies GC, Martyn DA, Regnier M, Barsotti RJ. Kinetics of cardiac thin-filament activation probed by fluorescence polarization of rhodamine-labeled troponin C in skinned guinea pig trabeculae. Biophysical Journal. 90: 531-43. PMID 16258047 DOI: 10.1529/Biophysj.105.072769  0.516
2005 Clemmens EW, Entezari M, Martyn DA, Regnier M. Different effects of cardiac versus skeletal muscle regulatory proteins on in vitro measures of actin filament speed and force. The Journal of Physiology. 566: 737-46. PMID 15905219 DOI: 10.1113/Jphysiol.2005.084194  0.544
2005 Moreno-Gonzalez A, Fredlund J, Regnier M. Cardiac troponin C (TnC) and a site I skeletal TnC mutant alter Ca2+ versus crossbridge contribution to force in rabbit skeletal fibres. The Journal of Physiology. 562: 873-84. PMID 15611027 DOI: 10.1113/Jphysiol.2004.077891  0.839
2004 Clemmens EW, Regnier M. Skeletal regulatory proteins enhance thin filament sliding speed and force by skeletal HMM. Journal of Muscle Research and Cell Motility. 25: 515-25. PMID 15711882 DOI: 10.1007/S10974-004-3787-0  0.454
2004 Regnier M, Martin H, Barsotti RJ, Rivera AJ, Martyn DA, Clemmens E. Cross-bridge versus thin filament contributions to the level and rate of force development in cardiac muscle Biophysical Journal. 87: 1815-1824. PMID 15345560 DOI: 10.1529/Biophysj.103.039123  0.605
2004 Adhikari BB, Regnier M, Rivera AJ, Kreutziger KL, Martyn DA. Cardiac length dependence of force and force redevelopment kinetics with altered cross-bridge cycling. Biophysical Journal. 87: 1784-94. PMID 15345557 DOI: 10.1529/Biophysj.103.039131  0.787
2004 Martyn DA, Adhikari BB, Regnier M, Gu J, Xu S, Yu LC. Response of equatorial x-ray reflections and stiffness to altered sarcomere length and myofilament lattice spacing in relaxed skinned cardiac muscle. Biophysical Journal. 86: 1002-11. PMID 14747335 DOI: 10.1016/S0006-3495(04)74175-2  0.463
2003 Gordon AM, Rivera AJ, Wang CK, Regnier M. Cooperative activation of skeletal and cardiac muscle. Advances in Experimental Medicine and Biology. 538: 371-8; discussion 37. PMID 15098683  0.309
2003 Liang B, Chen Y, Wang CK, Luo Z, Regnier M, Gordon AM, Chase PB. Ca2+ regulation of rabbit skeletal muscle thin filament sliding: role of cross-bridge number. Biophysical Journal. 85: 1775-86. PMID 12944292 DOI: 10.1016/S0006-3495(03)74607-4  0.521
2003 Köhler J, Chen Y, Brenner B, Gordon AM, Kraft T, Martyn DA, Regnier M, Rivera AJ, Wang CK, Chase PB. Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding. Physiological Genomics. 14: 117-28. PMID 12759477 DOI: 10.1152/Physiolgenomics.00101.2002  0.414
2002 Martyn DA, Chase PB, Regnier M, Gordon AM. A simple model with myofilament compliance predicts activation-dependent crossbridge kinetics in skinned skeletal fibers. Biophysical Journal. 83: 3425-34. PMID 12496109 DOI: 10.1016/S0006-3495(02)75342-3  0.526
2002 Regnier M, Rivera AJ, Wang CK, Bates MA, Chase PB, Gordon AM. Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations. The Journal of Physiology. 540: 485-97. PMID 11956338 DOI: 10.1113/Jphysiol.2001.013179  0.569
2001 Gordon AM, Regnier M, Homsher E. Skeletal and cardiac muscle contractile activation: tropomyosin "rocks and rolls". News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 16: 49-55. PMID 11390948  0.458
2001 Sieck GC, Regnier M. Invited review: Plasticity and energetic demands of contraction in skeletal and cardiac muscle Journal of Applied Physiology. 90: 1158-1164. PMID 11181631 DOI: 10.1152/Jappl.2001.90.3.1158  0.432
2001 Martyn DA, Regnier M, Xu D, Gordon AM. Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle. Biophysical Journal. 80: 360-70. PMID 11159408 DOI: 10.1016/S0006-3495(01)76020-1  0.453
2001 Gordon AM, Regnier M, Homsher E. Skeletal and Cardiac Muscle Contractile Activation: Tropomyosin “Rocks and Rolls” Physiology. 16: 49-55. DOI: 10.1152/Physiologyonline.2001.16.2.49  0.547
2000 Regnier M, Rivera AJ, Chen Y, Chase PB. 2-deoxy-ATP enhances contractility of rat cardiac muscle. Circulation Research. 86: 1211-7. PMID 10864910 DOI: 10.1161/01.Res.86.12.1211  0.496
2000 Gordon AM, Homsher E, Regnier M. Regulation of contraction in striated muscle. Physiological Reviews. 80: 853-924. PMID 10747208 DOI: 10.1152/Physrev.2000.80.2.853  0.519
1999 Regnier M, Chase PB, Martyn DA. Contractile properties of rabbit psoas muscle fibres inhibited by beryllium fluoride. Journal of Muscle Research and Cell Motility. 20: 425-32. PMID 10531623 DOI: 10.1023/A:1005594001334  0.433
1999 Regnier M, Rivera AJ, Chase PB, Smillie LB, Sorenson MM. Regulation of skeletal muscle tension redevelopment by troponin C constructs with different Ca2+ affinities. Biophysical Journal. 76: 2664-72. PMID 10233080 DOI: 10.1016/S0006-3495(99)77418-7  0.506
1998 Regnier M, Homsher E. The effect of ATP analogs on posthydrolytic and force development steps in skinned skeletal muscle fibers Biophysical Journal. 74: 3059-3071. PMID 9635760 DOI: 10.1016/S0006-3495(98)78013-0  0.415
1998 Regnier M, Lee DM, Homsher E. ATP analogs and muscle contraction: Mechanics and kinetics of nucleoside triphosphate binding and hydrolysis Biophysical Journal. 74: 3044-3058. PMID 9635759 DOI: 10.1016/S0006-3495(98)78012-9  0.419
1998 Regnier M, Martyn DA, Chase PB. Calcium regulation of tension redevelopment kinetics with 2-deoxy-ATP or low [ATP] in rabbit skeletal muscle. Biophysical Journal. 74: 2005-15. PMID 9545059 DOI: 10.1016/S0006-3495(98)77907-X  0.415
1998 Martyn DA, Regnier M, Gordon AM. Both Ca+2 and crossbridges induce structural changes in cardiac muscle troponin C Faseb Journal. 12: A728.  0.407
1998 Regnier M, Martyn DA, Gordon AM. Structural changes in troponin C (TnC) induced by Ca+2 and crossbridges in skinned skeletal muscle fibers Faseb Journal. 12: A728.  0.308
1997 Homsher E, Lacktis J, Regnier M. Strain-dependent modulation of phosphate transients in rabbit skeletal muscle fibers Biophysical Journal. 72: 1780-1791. PMID 9083682 DOI: 10.1016/S0006-3495(97)78824-6  0.383
1996 Regnier M, Martyn DA, Chase PB. Calmidazolium alters Ca2+ regulation of tension redevelopment rate in skinned skeletal muscle. Biophysical Journal. 71: 2786-94. PMID 8913615 DOI: 10.1016/S0006-3495(96)79471-7  0.566
1995 Regnier M, Morris C, Homsher E. Regulation of the cross-bridge transition from a weakly to strongly bound state in skinned rabbit muscle fibers American Journal of Physiology - Cell Physiology. 269. PMID 8572183 DOI: 10.1152/Ajpcell.1995.269.6.C1532  0.446
1993 Regnier M, Herrera AA. Differential sensitivity to androgens within a sexually dimorphic muscle of male frogs (Xenopus laevis). Journal of Neurobiology. 24: 1215-28. PMID 8409979 DOI: 10.1002/Neu.480240908  0.317
1993 Regnier M, Herrera AA. Changes in contractile properties by androgen hormones in sexually dimorphic muscles of male frogs (Xenopus laevis). The Journal of Physiology. 461: 565-81. PMID 8350275 DOI: 10.1113/Jphysiol.1993.Sp019529  0.35
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