Gregory Longmore - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology, Human Development

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bota-Rabassedas N, Banerjee P, Niu Y, Cao W, Luo J, Xi Y, Tan X, Sheng K, Ahn YH, Lee S, Parra ER, Rodriguez-Canales J, Albritton J, Weiger M, Liu X, ... ... Longmore GD, et al. Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. Cell Reports. 35: 109009. PMID 33882319 DOI: 10.1016/j.celrep.2021.109009  0.01
2020 Sewell-Loftin MK, Katz JB, George SC, Longmore GD. Micro-strains in the extracellular matrix induce angiogenesis. Lab On a Chip. PMID 32614340 DOI: 10.1039/D0Lc00145G  0.01
2020 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, ... ... Longmore GD, et al. Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 32300252 DOI: 10.1038/S41580-020-0237-9  1
2019 Bayer SV, Grither WR, Brenot A, Hwang PY, Barcus CE, Ernst M, Pence P, Walter C, Pathak A, Longmore GD. DDR2 controls breast tumor stiffness and metastasis by regulating Integrin mediated mechanotransduction in CAFs. Elife. 8. PMID 31144616 DOI: 10.7554/Elife.45508  1
2019 Zhang K, Grither WR, Van Hove S, Biswas H, Ponik SM, Eliceiri KW, Keely PJ, Longmore GD. Correction: Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of cancer-associated fibroblasts (doi:10.1242/jcs.180539). Journal of Cell Science. 132. PMID 31048546 DOI: 10.1242/Jcs.232348  1
2019 Longmore GD, Hwang PY, Brenot A, George SC, King AC. Randomly distributed K14+ breast tumor cells polarize to the leading edge to direct collective migration in response to chemical and mechanical environmental cues. Cancer Research. PMID 30862718 DOI: 10.1158/0008-5472.Can-18-2828  0.01
2019 Nozaki M, Yabuta N, Fukuzawa M, Mukai S, Okamoto A, Sasakura T, Fukushima K, Naito Y, Longmore GD, Nojima H. LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer. Oncotarget. 10: 1014-1030. PMID 30800215 DOI: 10.18632/oncotarget.26583  1
2018 Grither WR, Longmore GD. Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain. Proceedings of the National Academy of Sciences of the United States of America. 115: E7786-E7794. PMID 30061414 DOI: 10.1073/pnas.1805020115  1
2018 Brenot A, Knolhoff BL, DeNardo DG, Longmore GD. SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion. Oncogenesis. 7: 32. PMID 29593211 DOI: 10.1038/s41389-018-0042-x  1
2018 Grither WR, Divine LM, Meller EH, Wilke DJ, Desai RA, Loza AJ, Zhao P, Lohrey A, Longmore GD, Fuh KC. TWIST1 induces expression of discoidin domain receptor 2 to promote ovarian cancer metastasis. Oncogene. PMID 29348456 DOI: 10.1038/s41388-017-0043-9  1
2017 Sewell-Loftin MK, Bayer SVH, Crist E, Hughes T, Joison SM, Longmore GD, George SC. Cancer-associated fibroblasts support vascular growth through mechanical force. Scientific Reports. 7: 12574. PMID 28974764 DOI: 10.1038/S41598-017-13006-X  0.01
2017 Nasrollahi S, Walter C, Loza AJ, Schimizzi GV, Longmore GD, Pathak A. Past matrix stiffness primes epithelial cells and regulates their future collective migration through a mechanical memory. Biomaterials. 146: 146-155. PMID 28918264 DOI: 10.1016/J.Biomaterials.2017.09.012  1
2017 Ye X, Brabletz T, Kang Y, Longmore GD, Nieto MA, Stanger BZ, Yang J, Weinberg RA. Upholding a role for EMT in breast cancer metastasis. Nature. 547: E1-E3. PMID 28682326 DOI: 10.1038/Nature22816  1
2017 Fuh K, Gibson A, Wilke D, Ilagan M, Hagemann A, McCourt C, Thaker P, Mutch D, Powell M, Longmore G. Abstract AP18: FUNCTIONAL GENOMIC SCREEN FOR ATTACHMENT AND INVASION IN METASTATIC OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap18  0.01
2016 Biswas H, Longmore GD. Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury. Plos One. 11: e0162636. PMID 27706205 DOI: 10.1371/journal.pone.0162636  1
2016 Loza AJ, Koride S, Schimizzi GV, Li B, Sun SX, Longmore GD. Cell density and actomyosin contractility control the organization of migrating collectives within an epithelium. Molecular Biology of the Cell. PMID 27605707 DOI: 10.1091/Mbc.E16-05-0329  1
2016 Jagannathan R, Schimizzi GV, Zhang K, Loza AJ, Yabuta N, Nojima H, Longmore GD. AJUBA LIM proteins limit Hippo activity in proliferating cells by sequestering the Hippo core kinase complex in the cytosol. Molecular and Cellular Biology. PMID 27457617 DOI: 10.1128/Mcb.00136-16  1
2016 Schimizzi GV, Maher MT, Loza AJ, Longmore GD. Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms. Plos One. 11: e0159881. PMID 27454609 DOI: 10.1371/Journal.Pone.0159881  1
2016 Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7: 11762. PMID 27272654 DOI: 10.1038/Ncomms11762  1
2016 Corsa CA, Brenot A, Grither WR, Van Hove S, Loza AJ, Zhang K, Ponik SM, Liu Y, DeNardo DG, Eliceiri KW, Keely PJ, Longmore GD. The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis. Cell Reports. PMID 27264173 DOI: 10.1016/J.Celrep.2016.05.033  1
2016 Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens CB, Shin J, Sawada A, Hindes AE, Dubrulle J, Schier AF, Longmore GD, Marlow FL, Solnica-Krezel L. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). PMID 27127268 DOI: 10.1242/dev.138859  1
2016 Zhang K, Grither WR, Van Hove S, Biswas H, Ponik SM, Eliceiri KW, Keely PJ, Longmore GD. Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of CAFs. Journal of Cell Science. PMID 27076520 DOI: 10.1242/Jcs.180539  1
2015 Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, ... ... Longmore GD, et al. Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development. Cell Reports. PMID 26725121 DOI: 10.1016/J.Celrep.2015.12.016  1
2015 Fraley SI, Wu PH, He L, Feng Y, Krisnamurthy R, Longmore GD, Wirtz D. Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions. Scientific Reports. 5: 14580. PMID 26423227 DOI: 10.1038/Srep14580  1
2015 Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens CB, Shin J, Sawada A, Hindes AE, Dubrulle J, Schier AF, Longmore GD, Marlow FL, Solnica-Krezel L. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). PMID 26160902 DOI: 10.1242/Dev.119800  1
2015 Schimizzi GV, Longmore GD. Ajuba proteins. Current Biology : Cb. 25: R445-6. PMID 26035782 DOI: 10.1016/j.cub.2015.02.034  1
2015 Tran HD, Kim M, Luitel K, Zhang K, Longmore G, Tran DD. Abstract 4084: Transient SNAIL1 expression is necessary for metastatic competence in breast cancer Cancer Research. 75: 4084-4084. DOI: 10.1158/1538-7445.Am2015-4084  1
2014 Tran HD, Luitel K, Kim M, Zhang K, Longmore GD, Tran DD. Transient SNAIL1 expression is necessary for metastatic competence in breast cancer. Cancer Research. 74: 6330-40. PMID 25164016 DOI: 10.1158/0008-5472.CAN-14-0923  1
2014 Yashiro H, Loza AJ, Skeath JB, Longmore GD. Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II. Molecular Biology of the Cell. 25: 2956-69. PMID 25079692 DOI: 10.1091/Mbc.E14-04-0894  1
2014 Viñas-Castells R, Frías Á, Robles-Lanuza E, Zhang K, Longmore GD, García de Herreros A, Díaz VM. Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Research. 42: 1079-94. PMID 24157836 DOI: 10.1093/nar/gkt935  1
2013 Bajpai S, Feng Y, Wirtz D, Longmore GD. β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths. Biophysical Journal. 105: 2289-300. PMID 24268141 DOI: 10.1016/J.Bpj.2013.09.044  1
2013 Giri A, Bajpai S, Trenton N, Jayatilaka H, Longmore GD, Wirtz D. The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4089-99. PMID 23796785 DOI: 10.1096/Fj.12-224352  1
2013 Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD. The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis. Nature Cell Biology. 15: 677-87. PMID 23644467 DOI: 10.1038/Ncb2743  1
2013 Feng Y, Ngu H, Alford SK, Ward M, Yin F, Longmore GD. α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation. Experimental Cell Research. 319: 1124-35. PMID 23454549 DOI: 10.1016/J.Yexcr.2013.02.009  1
2013 Chambliss AB, Khatau SB, Erdenberger N, Robinson DK, Hodzic D, Longmore GD, Wirtz D. The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Scientific Reports. 3: 1087. PMID 23336069 DOI: 10.1038/Srep01087  1
2012 Kim DH, Khatau SB, Feng Y, Walcott S, Sun SX, Longmore GD, Wirtz D. Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Scientific Reports. 2: 555. PMID 22870384 DOI: 10.1038/Srep00555  1
2012 Lee MH, Wu PH, Staunton JR, Ros R, Longmore GD, Wirtz D. Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer. Biophysical Journal. 102: 2731-41. PMID 22735523 DOI: 10.1016/J.Bpj.2012.05.005  1
2012 Fraley SI, Feng Y, Giri A, Longmore GD, Wirtz D. Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nature Communications. 3: 719. PMID 22395610 DOI: 10.1038/Ncomms1711  1
2012 Foxler DE, Bridge KS, James V, Webb TM, Mee M, Wong SC, Feng Y, Constantin-Teodosiu D, Petursdottir TE, Bjornsson J, Ingvarsson S, Ratcliffe PJ, Longmore GD, Sharp TV. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. Nature Cell Biology. 14: 201-8. PMID 22286099 DOI: 10.1038/Ncb2424  1
2012 Zhang K, Rodriguez-Aznar E, Yabuta N, Owen RJ, Mingot JM, Nojima H, Nieto MA, Longmore GD. Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. The Embo Journal. 31: 29-43. PMID 21952048 DOI: 10.1038/emboj.2011.357  1
2011 Nola S, Daigaku R, Smolarczyk K, Carstens M, Martin-Martin B, Longmore G, Bailly M, Braga VM. Ajuba is required for Rac activation and maintenance of E-cadherin adhesion. The Journal of Cell Biology. 195: 855-71. PMID 22105346 DOI: 10.1083/Jcb.201107162  1
2011 Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Molecular Cancer Research : McR. 9: 1644-57. PMID 22006115 DOI: 10.1158/1541-7786.MCR-11-0371  1
2011 Fraley SI, Feng Y, Wirtz D, Longmore GD. Reply: Reducing background fluorescence reveals adhesions in 3D matrices Nature Cell Biology. 13: 5-7. DOI: 10.1038/Ncb0111-5  1
2010 Feng Y, Nie L, Thakur MD, Su Q, Chi Z, Zhao Y, Longmore GD. A multifunctional lentiviral-based gene knockdown with concurrent rescue that controls for off-target effects of RNAi. Genomics, Proteomics & Bioinformatics. 8: 238-45. PMID 21382592 DOI: 10.1016/S1672-0229(10)60025-3  1
2010 Warner SJ, Longmore GD. Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis. Cell Cycle (Georgetown, Tex.). 9: 4037-8. PMID 20935485 DOI: 10.4161/Cc.9.20.13562  1
2010 James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV. LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 12499-504. PMID 20616046 DOI: 10.1073/Pnas.0914987107  1
2010 Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, Wirtz D. A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nature Cell Biology. 12: 598-604. PMID 20473295 DOI: 10.1038/Ncb2062  1
2010 Warner SJ, Yashiro H, Longmore GD. The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia. Current Biology : Cb. 20: 677-86. PMID 20381350 DOI: 10.1016/J.Cub.2010.03.025  1
2010 Alford SK, Wang Y, Feng Y, Longmore GD, Elbert DL. Prediction of sphingosine 1-phosphate-stimulated endothelial cell migration rates using biochemical measurements. Annals of Biomedical Engineering. 38: 2775-90. PMID 20358290 DOI: 10.1007/S10439-010-0014-6  1
2010 Das Thakur M, Feng Y, Jagannathan R, Seppa MJ, Skeath JB, Longmore GD. Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. Current Biology : Cb. 20: 657-62. PMID 20303269 DOI: 10.1016/J.Cub.2010.02.035  1
2010 Hou Z, Peng H, White DE, Negorev DG, Maul GG, Feng Y, Longmore GD, Waxman S, Zelent A, Rauscher FJ. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling Proceedings of the National Academy of Sciences of the United States of America. 107: 2938-2943. PMID 20133701 DOI: 10.1073/Pnas.0908656107  1
2010 Ngu H, Feng Y, Lu L, Oswald SJ, Longmore GD, Yin FC. Effect of focal adhesion proteins on endothelial cell adhesion, motility and orientation response to cyclic strain. Annals of Biomedical Engineering. 38: 208-22. PMID 19856213 DOI: 10.1007/S10439-009-9826-7  1
2009 Warner SJ, Longmore GD. Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. The Journal of Cell Biology. 187: 119-33. PMID 19805632 DOI: 10.1083/Jcb.200906047  1
2009 Hadland BK, Longmore GD. Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 4217-26. PMID 19636005 DOI: 10.1200/JCO.2008.21.6945  1
2009 Warner SJ, Longmore GD. Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia. The Journal of Cell Biology. 185: 1111-25. PMID 19506041 DOI: 10.1083/Jcb.200901029  1
2009 Bajpai S, Feng Y, Krishnamurthy R, Longmore GD, Wirtz D. Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. The Journal of Biological Chemistry. 284: 18252-9. PMID 19458087 DOI: 10.1074/Jbc.M109.000661  1
2009 Schindler EM, Hindes A, Gribben EL, Burns CJ, Yin Y, Lin MH, Owen RJ, Longmore GD, Kissling GE, Arthur JS, Efimova T. p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Research. 69: 4648-55. PMID 19458068 DOI: 10.1158/0008-5472.CAN-08-4455  1
2008 Sharp TV, Al-Attar A, Foxler DE, Ding L, de A Vallim TQ, Zhang Y, Nijmeh HS, Webb TM, Nicholson AG, Zhang Q, Kraja A, Spendlove I, Osborne J, Mardis E, Longmore GD. The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development. Proceedings of the National Academy of Sciences of the United States of America. 105: 19932-7. PMID 19060205 DOI: 10.1073/Pnas.0805003105  1
2008 Bajpai S, Correia J, Feng Y, Figueiredo J, Sun SX, Longmore GD, Suriano G, Wirtz D. {alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proceedings of the National Academy of Sciences of the United States of America. 105: 18331-6. PMID 19017792 DOI: 10.1073/Pnas.0806783105  1
2008 Montoya-Durango DE, Velu CS, Kazanjian A, Rojas ME, Jay CM, Longmore GD, Grimes HL. Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. The Journal of Biological Chemistry. 283: 32056-65. PMID 18805794 DOI: 10.1074/Jbc.M802320200  1
2008 Spendlove I, Al-Attar A, Watherstone O, Webb TM, Ellis IO, Longmore GD, Sharp TV. Differential subcellular localisation of the tumour suppressor protein LIMD1 in breast cancer correlates with patient survival. International Journal of Cancer. Journal International Du Cancer. 123: 2247-53. PMID 18712738 DOI: 10.1002/ijc.23851  1
2008 Alford SK, Longmore GD, Stenson WF, Kemper C. CD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 2544-55. PMID 18684945 DOI: 10.4049/Jimmunol.181.4.2544  1
2008 Luderer HF, Bai S, Longmore GD. The LIM protein LIMD1 influences osteoblast differentiation and function. Experimental Cell Research. 314: 2884-94. PMID 18657804 DOI: 10.1016/J.Yexcr.2008.06.003  1
2008 Epple H, Cremasco V, Zhang K, Mao D, Longmore GD, Faccio R. Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase. Molecular and Cellular Biology. 28: 3610-22. PMID 18378693 DOI: 10.1128/Mcb.00259-08  1
2008 Hou Z, Peng H, Ayyanathan K, Yan KP, Langer EM, Longmore GD, Rauscher FJ. The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression. Molecular and Cellular Biology. 28: 3198-207. PMID 18347060 DOI: 10.1128/Mcb.01435-07  1
2008 Langer EM, Feng Y, Zhaoyuan H, Rauscher FJ, Kroll KL, Longmore GD. Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Developmental Cell. 14: 424-36. PMID 18331720 DOI: 10.1016/j.devcel.2008.01.005  1
2008 Lu L, Feng Y, Hucker WJ, Oswald SJ, Longmore GD, Yin FC. Actin stress fiber pre-extension in human aortic endothelial cells. Cell Motility and the Cytoskeleton. 65: 281-94. PMID 18200567 DOI: 10.1002/Cm.20260  1
2008 Wacker BK, Alford SK, Scott EA, Das Thakur M, Longmore GD, Elbert DL. Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. Biophysical Journal. 94: 273-85. PMID 17827231 DOI: 10.1529/Biophysj.107.109074  1
2007 Giurisato E, Cella M, Takai T, Kurosaki T, Feng Y, Longmore GD, Colonna M, Shaw AS. Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse. Molecular and Cellular Biology. 27: 8583-99. PMID 17923698 DOI: 10.1128/Mcb.01477-07  1
2007 Ayyanathan K, Peng H, Hou Z, Fredericks WJ, Goyal RK, Langer EM, Longmore GD, Rauscher FJ. The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling. Cancer Research. 67: 9097-106. PMID 17909014 DOI: 10.1158/0008-5472.Can-07-2987  1
2007 Longmore GD. Do cancer cells express functional erythropoietin receptors? The New England Journal of Medicine. 356: 2447. PMID 17568024 DOI: 10.1056/NEJMp078112  1
2007 Feng Y, Zhao H, Luderer HF, Epple H, Faccio R, Ross FP, Teitelbaum SL, Longmore GD. The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development. The Journal of Biological Chemistry. 282: 39-48. PMID 17092936 DOI: 10.1074/Jbc.M607399200  1
2006 Longmore GD. A unique role for Stat5 in recovery from acute anemia. The Journal of Clinical Investigation. 116: 626-8. PMID 16511596 DOI: 10.1172/JCI27988  1
2005 Jones KB, Anderson DW, Longmore GD. Effects of recombinant hematopoietins on blood-loss anemia in mice. The Iowa Orthopaedic Journal. 25: 129-34. PMID 16089085  1
2005 Feng Y, Longmore GD. The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. Molecular and Cellular Biology. 25: 4010-22. PMID 15870274 DOI: 10.1128/MCB.25.10.4010-4022.2005  1
2005 Kisseleva M, Feng Y, Ward M, Song C, Anderson RA, Longmore GD. The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha. Molecular and Cellular Biology. 25: 3956-66. PMID 15870270 DOI: 10.1128/MCB.25.10.3956-3966.2005  1
2005 Pratt SJ, Epple H, Ward M, Feng Y, Braga VM, Longmore GD. The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. The Journal of Cell Biology. 168: 813-24. PMID 15728191 DOI: 10.1083/Jcb.200406083  1
2004 Hadland BK, Huppert SS, Kanungo J, Xue Y, Jiang R, Gridley T, Conlon RA, Cheng AM, Kopan R, Longmore GD. A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood. 104: 3097-105. PMID 15251982 DOI: 10.1182/Blood-2004-03-1224  1
2004 Young AP, Longmore GD. Differential regulation of apoptotic genes by Rb in human versus mouse cells. Oncogene. 23: 2587-99. PMID 15048095 DOI: 10.1038/Sj.Onc.1207330  1
2004 Young AP, Longmore GD. Differences in stability of repressor complexes at promoters underlie distinct roles for Rb family members. Oncogene. 23: 814-23. PMID 14737116 DOI: 10.1038/Sj.Onc.1207187  1
2004 Young AP, Longmore GD. Ras protects Rb family null fibroblasts from cell death: a role for AP-1. The Journal of Biological Chemistry. 279: 10931-8. PMID 14688262 DOI: 10.1074/Jbc.M311814200  1
2003 Young AP, Nagarajan R, Longmore GD. Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene. 22: 7209-17. PMID 14562049 DOI: 10.1038/Sj.Onc.1206804  1
2003 Marie H, Pratt SJ, Betson M, Epple H, Kittler JT, Meek L, Moss SJ, Troyanovsky S, Attwell D, Longmore GD, Braga VM. The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. The Journal of Biological Chemistry. 278: 1220-8. PMID 12417594 DOI: 10.1074/Jbc.M205391200  1
2002 Marie H, Billups D, Bedford FK, Dumoulin A, Goyal RK, Longmore GD, Moss SJ, Attwell D. The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. Molecular and Cellular Neurosciences. 19: 152-64. PMID 11860269 DOI: 10.1006/mcne.2001.1066  1
2002 Afrikanova I, Yeh E, Bartos D, Watowich SS, Longmore GD. Oncogene cooperativity in Friend erythroleukemia: erythropoietin receptor activation by the env gene of SFFV leads to transcriptional upregulation of PU.1, independent of SFFV proviral insertion. Oncogene. 21: 1272-84. PMID 11850847 DOI: 10.1038/Sj.Onc.1205183  1
2001 Hadland BK, Manley NR, Su D, Longmore GD, Moore CL, Wolfe MS, Schroeter EH, Kopan R. Gamma -secretase inhibitors repress thymocyte development. Proceedings of the National Academy of Sciences of the United States of America. 98: 7487-91. PMID 11416218 DOI: 10.1073/Pnas.131202798  1
2000 Watowich SS, Mikami A, Busche RA, Xie X, Pharr PN, Longmore GD. Erythropoietin receptors that signal through Stat5 or Stat3 support fetal liver and adult erythropoiesis: Lack of specificity of Stat signals during red blood cell development Journal of Interferon and Cytokine Research. 20: 1065-1070. PMID 11152572 DOI: 10.1089/107999000750053726  1
2000 Kanungo J, Pratt SJ, Marie H, Longmore GD. Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions. Molecular Biology of the Cell. 11: 3299-313. PMID 11029037 DOI: 10.1091/Mbc.11.10.3299  1
2000 Wooten DK, Xie X, Bartos D, Busche RA, Longmore GD, Watowich SS. Cytokine signaling through Stat3 activates integrins, promotes adhesion, and induces growth arrest in the myeloid cell line 32D Journal of Biological Chemistry. 275: 26566-26575. PMID 10858439 DOI: 10.1074/Jbc.M003495200  1
1999 Beckman DL, Lin LL, Quinones ME, Longmore GD. Activation of the erythropoietin receptor is not required for internalization of bound erythropoietin. Blood. 94: 2667-75. PMID 10515870  1
1999 Goyal RK, Longmore GD. Abnormalities of cytokine receptor signalling contributing to diseases of red blood cell production Annals of Medicine. 31: 208-216. PMID 10442676  1
1999 Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MA. Genetic evidence for an additional factor required for erythropoietin- induced signal transduction Blood. 94: 74-86. PMID 10381500 DOI: 10.1182/Blood.V94.1.74.413K36_74_86  1
1999 Goyal RK, Lin P, Kanungo J, Payne AS, Muslin AJ, Longmore GD. Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen- activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner Molecular and Cellular Biology. 19: 4379-4389. PMID 10330178 DOI: 10.1128/Mcb.19.6.4379  1
1999 Watowich SS, Liu KD, Xie X, Lai SY, Mikami A, Longmore GD, Goldsmith MA. Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail Journal of Biological Chemistry. 274: 5415-5421. PMID 10026152 DOI: 10.1074/Jbc.274.9.5415  1
1998 Goldsmith MA, Mikami A, You Y, Liu KD, Thomas L, Pharr P, Longmore GD. Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivo Proceedings of the National Academy of Sciences of the United States of America. 95: 7006-7011. PMID 9618529 DOI: 10.1073/Pnas.95.12.7006  1
1998 Zamorano J, Wang HY, Wang R, Shi Y, Longmore GD, Keegan AD. Regulation of cell growth by IL-2: Role of STAT5 in protection from apoptosis but not in cell cycle progression Journal of Immunology. 160: 3502-3512. PMID 9531312  1
1998 Longmore GD, You Y, Molden J, Liu KD, Mikami A, Lai SY, Pharr P, Goldsmith MA. Redundant and selective roles for erythropoietin receptor tyrosines in erythropoiesis in vivo Blood. 91: 870-878. PMID 9446647 DOI: 10.1182/Blood.V91.3.870.870_870_878  1
1997 Tarr K, Watowich SS, Longmore GD. Cell surface organization of the erythropoietin receptor complex differs depending on its mode of activation Journal of Biological Chemistry. 272: 9099-9107. PMID 9083037 DOI: 10.1074/Jbc.272.14.9099  1
1996 Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. The molecular role of the common γ subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes Proceedings of the National Academy of Sciences of the United States of America. 93: 231-235. PMID 8552611 DOI: 10.1073/Pnas.93.1.231  1
1995 Tanner JW, Chen W, Young RL, Longmore GD, Shaw AS. The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. The Journal of Biological Chemistry. 270: 6523-30. PMID 7896787 DOI: 10.1074/Jbc.270.12.6523  1
1995 Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the β chain and non-tyrosine residues of the γc chain Journal of Biological Chemistry. 270: 21729-21737. PMID 7665592 DOI: 10.1074/Jbc.270.37.21729  1
1995 McArthur GA, Longmore GD, Klingler K, Johnson GR. Lineage-restricted recruitment of immature hematopoietic progenitor cells in response to Epo after normal hematopoietic cell transfection with EpoR Experimental Hematology. 23: 645-654. PMID 7601257  1
1994 Levin J, Ebbe S, Longmore G, Harrison JS, Abraham NG. Why are recently published platelet counts in normal mice so low? [4] Blood. 83: 3829-3831. PMID 8204902  1
1994 Longmore GD, Pharr PN, Lodish HF. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells Molecular and Cellular Biology. 14: 2266-2277. PMID 8139532 DOI: 10.1128/Mcb.14.4.2266  1
1994 Pharr PN, Ogawa M, Hofbauer A, Longmore GD. Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation Proceedings of the National Academy of Sciences of the United States of America. 91: 7482-7486. PMID 8052607 DOI: 10.1073/Pnas.91.16.7482  1
1993 Youssoufian H, Longmore G, Neumann D, Yoshimura A, Lodish HF. Structure, function, and activation of the erythropoietin receptor Blood. 81: 2223-2236. PMID 8481505 DOI: 10.1182/Blood.V81.9.2223.2223  1
1993 Longmore GD, Pharr P, Neumann D, Lodish HF. Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor Blood. 82: 2386-2395. PMID 8400289  1
1993 Longmore G, Watowich S, Pharr P, Neumann D, Lodish H. Activation of the erythropoietin receptor and leukemia induction in mice Leukemia. 7. PMID 8361212  1
1993 Longmore GD. Erythropoietin receptor mutations and Olympic glory Nature Genetics. 4: 108-110. PMID 8348144 DOI: 10.1038/ng0693-108  1
1993 Longmore GD, Watowich SS, Hilton DJ, Lodish HF. The erythropoietin receptor: Its role in hematopoiesis and myeloproliferative diseases Journal of Cell Biology. 123: 1305-1308. PMID 8253831 DOI: 10.1083/Jcb.123.6.1305  1
1993 Pharr PN, Hankins D, Hofbauer A, Lodish HF, Longmore GD. Expression of a constitutively active erythropoietin receptor in primary hematopoietic progenitors abrogates erythropoietin dependence and enhances erythroid colony-forming unit, erythroid burst-forming unit, and granulocyte/macrophage progenitor growth Proceedings of the National Academy of Sciences of the United States of America. 90: 938-942. PMID 7679218  1
1993 Longmore G, Pharr P, Neumann D, Lodish H. Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor [see comments] Blood. 82: 2386-2395. DOI: 10.1182/Blood.V82.8.2386.Bloodjournal8282386  1
1992 Lodish HF, Hilton D, Longmore G, Watowich SS, Yoshimura A. The erythropoietin receptor: Dimerization, activation, and tumorigenesis Cold Spring Harbor Symposia On Quantitative Biology. 57: 95-106. PMID 1339709 DOI: 10.1101/Sqb.1992.057.01.013  1
1992 Longmore GD, Pharr P, Lodish HF. Mutation in murine erythropoietin receptor induces erythropoietin-independent erythroid proliferation in vitro, polycythemia in vivo Leukemia. 6. PMID 1318465  1
1992 Yoshimura A, Zimmers T, Neumann D, Longmore G, Yoshimura Y, Lodish HF. Mutations in the Trp-Ser-X-Trp-Ser motif of the erythropoietin receptor abolish processing, ligand binding, and activation of the receptor Journal of Biological Chemistry. 267: 11619-11625. PMID 1317872  1
1992 Watowich SS, Yoshimura A, Longmore GD, Hilton DJ, Yoshimura Y, Lodish HF. Homodimerization and constitutive activation of the erythropoietin receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 2140-2144. PMID 1312714 DOI: 10.1073/Pnas.89.6.2140  1
1992 Baliga BS, Isoyama K, Longmore G, Yang YM, Shah AK, Mankad VN. A simple method for hemoglobin measurement in cell culture system Blood Cells. 18: 187-193. PMID 1280484  1
1991 Longmore GD, Lodish HF. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene Cell. 67: 1089-1102. PMID 1662116 DOI: 10.1016/0092-8674(91)90286-8  1
1990 Longmore G, Guinan EC, Weinstein HJ, Gelber RD, Rappeport JM, Antin JH. Bone marrow transplantation for myelodysplasia and secondary acute nonlymphoblastic leukemia Journal of Clinical Oncology. 8: 1707-1714. PMID 2213106 DOI: 10.1200/Jco.1990.8.10.1707  1
1990 Yoshimura A, Longmore G, Lodish HF. Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity Nature. 348: 647-649. PMID 2174515 DOI: 10.1038/348647A0  1
1986 Kline LW, Longmore GA. Determination of calcitonin in reptilian serum by heterologous radioimmunoassay General and Comparative Endocrinology. 61: 1-4. PMID 3940923 DOI: 10.1016/0016-6480(86)90242-X  1
1986 Hubbard SC, Kranz DM, Longmore GD, Sitkovsky MV, Eisen HN. Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 83: 1852-6. PMID 3081904 DOI: 10.1073/Pnas.83.6.1852  1
1986 Wigglesworth DJ, Longmore GA, Kuc IM, Murdoch C. Early dentinogenesis in mice: Von Korff fibres and their possible significance. A preliminary study by light and electron microscopy Acta Anatomica. 127: 151-160. PMID 2431593  1
1982 Longmore GD, Schachter H. Product-identification and substrate-specificity studies of the GDP-l-fucose: 2-acetamido-2-deoxy-β-d-glucoside (fuc→asn-linked GlcNAc) 6-α-l-fucosyltransferase in a golgi-rich fraction from porcine liver Carbohydrate Research. 100: 365-392. PMID 7083256 DOI: 10.1016/S0008-6215(00)81049-6  1
1980 Narasimhan S, Harpaz N, Longmore G, Carver JP, Grey AA, Schachter H. Control of glycoprotein synthesis. The purification by preparative high voltage paper electrophoresis in borate of glycopeptides containing high mannose and complex oligosaccharide chains linked to asparagine Journal of Biological Chemistry. 255: 4876-4884. PMID 7372614  1
1980 Williams D, Longmore G, Matta KL, Schachter H. Mucin synthesis. II. Substrate specificity and product identification studies on canine submaxillary gland UDP-GlcNAc:Gal beta 1-3GalNAc(GlcNAc leads to GalNAc) beta 6-N-acetylglucosaminyltransferase Journal of Biological Chemistry. 255: 11253-11261. PMID 6449508  1
1968 Shatin L, Kotter W, Longmore G. Personality traits of music therapists Psychological Reports. 23: 573-574. PMID 5698805  1
1967 Shatin L, Kotter W, Longmore G. Psycho-social prescription for music therapy in hospitals Diseases of the Nervous System. 28: 231-233. PMID 6024060  1
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