Jiandong Chen - Publications

Biology (Cell Biology, Microbiology, Molecular Biology) University of South Florida, Tampa, FL, United States 
Molecular Biology, Cell Biology, Oncology, Genetics

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Huang Q, Chen L, Schonbrunn E, Chen J. MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling. The Embo Journal. e104410. PMID 32511789 DOI: 10.15252/embj.2020104410  0.72
2020 Sang P, Shi Y, Lu J, Chen L, Yang L, Borcherds W, Abdulkadir S, Li Q, Daughdrill GW, Chen J, Cai J. α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions. Journal of Medicinal Chemistry. PMID 31971801 DOI: 10.1021/acs.jmedchem.9b00993  0.72
2019 Liu X, Huang Q, Chen L, Zhang H, Schonbrunn E, Chen J. Tumor-derived CK1α mutations enhance MDMX inhibition of p53. Oncogene. PMID 31462704 DOI: 10.1038/s41388-019-0979-z  0.72
2019 He F, Borcherds W, Song T, Wei X, Das M, Chen L, Daughdrill GW, Chen J. Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 30988205 DOI: 10.1073/pnas.1903077116  0.72
2018 Yang L, Song T, Cheng Q, Chen L, Chen J. Mutant p53 sequestration of MDM2 acidic domain inhibits E3 ligase activity. Molecular and Cellular Biology. PMID 30455251 DOI: 10.1128/MCB.00375-18  0.72
2018 Huang Q, Chen L, Yang L, Xie X, Gan L, Cleveland JL, Chen J. MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581299 DOI: 10.1073/pnas.1719090115  0.72
2017 Yang L, Fang J, Chen J. Tumor cell senescence response produces aggressive variants. Cell Death Discovery. 3: 17049. PMID 28845296 DOI: 10.1038/cddiscovery.2017.49  0.52
2017 Borcherds W, Becker A, Chen L, Chen J, Chemes LB, Daughdrill GW. Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX. Biophysical Journal. PMID 28487147 DOI: 10.1016/j.bpj.2017.04.017  0.72
2016 Zhang H, Xie H, Zheng X, Chai Y, Tang Z, Chen H, Li F, Christoph H, Chen J, Sun W, Ye H, Wang S, Hao H, Chen X. Salicylic acid retention impairs aspirin reactivity in type 2 diabetes. European Journal of Pharmacology. PMID 27894813 DOI: 10.1016/j.ejphar.2016.11.042  0.32
2016 Bragg F, Li L, Bennett D, Guo Y, Lewington S, Bian Z, Yang L, Chen J, Chen Y, Collins R, Peto R, Zhu B, Yin J, Hu X, Zhou L, et al. Association of Random Plasma Glucose Levels With the Risk for Cardiovascular Disease Among Chinese Adults Without Known Diabetes. Jama Cardiology. PMID 27437922 DOI: 10.1001/jamacardio.2016.1702  0.96
2016 Liu X, He B, Cho WC, Pan Y, Chen J, Ying H, Wang F, Lin K, Peng H, Wang S. A systematic review on the association between the Helicobacter pylori vacA i genotype and gastric disease. Febs Open Bio. 6: 409-17. PMID 27419046 DOI: 10.1002/2211-5463.12046  0.96
2016 Zhang Y, Pan Y, Lin C, Zheng Y, Sun H, Zhang H, Wang J, Yuan M, Duan T, Du Q, Chen J. Bile acids evoke placental inflammation by activating Gpbar1/NF-κB pathway in intrahepatic cholestasis of pregnancy. Journal of Molecular Cell Biology. PMID 27402811 DOI: 10.1093/jmcb/mjw025  0.96
2016 Pan Y, Lv X, Zhang H, Chen J, Han B, Shen Z, Lu J, Ni X. Millisecond laser machining of transparent materials assisted by a nanosecond laser with different delays. Optics Letters. 41: 2807-2810. PMID 27304294  0.96
2016 Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Oncogene. PMID 27270429 DOI: 10.1038/onc.2016.196  0.96
2016 Chen Y, Li C, Pan Y, Han S, Feng B, Gao Y, Chen J, Zhang K, Wang R, Chen L. The Emerging Role and Promise of Long Noncoding RNAs in Lung Cancer Treatment. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 2194-2206. PMID 27183839 DOI: 10.1159/000445575  0.96
2016 Tian J, Chen J, Ge C, Liu X, He J, Ni P, Pan Y. Synthesis of PEGylated Ferrocene Nanoconjugates as the Radiosensitizer of Cancer Cells. Bioconjugate Chemistry. PMID 27120689 DOI: 10.1021/acs.bioconjchem.6b00168  0.96
2016 Wei M, Zhang J, Jia M, Yang C, Pan Y, Li S, Luo Y, Zheng J, Ji J, Chen J, Hu X, Xiong J, Shi Y, Zhang C. α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114538 DOI: 10.1073/pnas.1524589113  0.96
2016 Wei X, Wu S, Song T, Chen L, Gao M, Borcherds W, Daughdrill GW, Chen J. Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114532 DOI: 10.1073/pnas.1603838113  1
2016 Sun H, Pan Y, He B, Deng Q, Ying H, Chen J, Liu X, Wang S. Different effects of the three polymorphisms on 15q25.1 onlung cancer risk: Evidence from published literatures. Journal of Cancer Research and Therapeutics. 12: 12-9. PMID 27072204 DOI: 10.4103/0973-1482.151863  0.96
2016 Pan Y, Shi Y, Chen Z, Chen J, Hou M, Chen Z, Li CW, Yi C. Design of multiple logic gates based on chemically triggered fluorescence switching of functionalized polyethyleneimine. Acs Applied Materials & Interfaces. PMID 27007856 DOI: 10.1021/acsami.6b02080  0.96
2016 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Chen JC, et al. Observation of the Singly Cabibbo-Suppressed Decay D^{+}→ωπ^{+} and Evidence for D^{0}→ωπ^{0}. Physical Review Letters. 116: 082001. PMID 26967411 DOI: 10.1103/PhysRevLett.116.082001  0.52
2016 Huang X, Yue Y, Li D, Zhao Y, Qiu L, Chen J, Pan Y, Xi J, Wang X, Sun Q, Li Q. Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy. Scientific Reports. 6: 22303. PMID 26923481 DOI: 10.1038/srep22303  0.96
2016 Adamczyk L, Adkins JK, Agakishiev G, Aggarwal MM, Ahammed Z, Alekseev I, Aparin A, Arkhipkin D, Aschenauer EC, Averichev GS, Bairathi V, Banerjee A, Bellwied R, Bhasin A, Bhati AK, ... ... Chen JH, et al. Centrality and Transverse Momentum Dependence of Elliptic Flow of Multistrange Hadrons and ϕ Meson in Au+Au Collisions at sqrt[s_{NN}]=200  GeV. Physical Review Letters. 116: 062301. PMID 26918982 DOI: 10.1103/PhysRevLett.116.062301  0.32
2016 Chen J, Zhou HC, Pan Y, Shyla FS, Tam NF. Effects of polybrominated diphenyl ethers and plant species on nitrification, denitrification and anammox in mangrove soils. The Science of the Total Environment. 553: 60-70. PMID 26901803 DOI: 10.1016/j.scitotenv.2016.02.052  0.6
2016 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Chen JC, et al. Measurements of Absolute Hadronic Branching Fractions of the Λ_{c}^{+} Baryon. Physical Review Letters. 116: 052001. PMID 26894702 DOI: 10.1103/PhysRevLett.116.052001  0.52
2016 Chohan TA, Chen JJ, Qian HY, Pan YL, Chen JZ. Molecular modeling studies to characterize N-phenylpyrimidin-2-amine selectivity for CDK2 and CDK4 through 3D-QSAR and molecular dynamics simulations. Molecular Biosystems. PMID 26883408 DOI: 10.1039/c5mb00860c  0.56
2016 Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen JQ, Herrmann MA, Kumar S, Kalab P. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Molecular Biology of the Cell. PMID 26864624 DOI: 10.1091/mbc.E16-01-0025  0.32
2015 Adamczyk L, Adkins JK, Agakishiev G, Aggarwal MM, Ahammed Z, Alekseev I, Alford J, Aparin A, Arkhipkin D, Aschenauer EC, Averichev GS, Banerjee A, Bellwied R, Bhasin A, Bhati AK, ... ... Chen JH, et al. Observation of Transverse Spin-Dependent Azimuthal Correlations of Charged Pion Pairs in p^{↑}+p at sqrt[s]=200  GeV. Physical Review Letters. 115: 242501. PMID 26705627 DOI: 10.1103/PhysRevLett.115.242501  0.32
2015 Zhang Z, Pan Y, Fang Y, Zhang L, Chen J, Yi C. Tuning photoluminescence and surface properties of carbon nanodots for chemical sensing. Nanoscale. 8: 500-7. PMID 26676688 DOI: 10.1039/c5nr06534h  0.96
2015 Gao T, He B, Pan Y, Deng Q, Sun H, Liu X, Chen J, Wang S, Xia Y. Association of Clostridium difficile infection in hospital mortality: A systematic review and meta-analysis. American Journal of Infection Control. 43: 1316-1320. PMID 26654234 DOI: 10.1016/j.ajic.2015.04.209  0.96
2015 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Ferroli RB, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Chen JC, et al. Observation of a Neutral Structure near the DD[over ¯]^{*} Mass Threshold in e^{+}e^{-}→(DD[over ¯]^{*})^{0}π^{0} at sqrt[s]=4.226 and 4.257 GeV. Physical Review Letters. 115: 222002. PMID 26650295 DOI: 10.1103/PhysRevLett.115.222002  0.52
2015 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Chen JC, et al. Measurement of the Absolute Branching Fraction for Λ_{c}^{+}→Λe^{+}ν_{e}. Physical Review Letters. 115: 221805. PMID 26650293 DOI: 10.1103/PhysRevLett.115.221805  0.52
2015 Chen Y, Gao Y, Zhang K, Li C, Pan Y, Chen J, Wang R, Chen L. MicroRNAs as Regulators of Cisplatin Resistance in Lung Cancer. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 37: 1869-1880. PMID 26584286 DOI: 10.1159/000438548  0.96
2015 Chohan TA, Qian HY, Pan YL, Chen JZ. Molecular simulation studies on the binding selectivity of 2-anilino-4-(thiazol-5-yl)-pyrimidines in complexes with CDK2 and CDK7. Molecular Biosystems. PMID 26565382 DOI: 10.1039/c5mb00630a  0.56
2015 Wu Q, Zhong ZM, Zhu SY, Liao CR, Pan Y, Zeng JH, Zheng S, Ding RT, Lin QS, Ye Q, Ye WB, Li W, Chen JT. Advanced oxidation protein products induce chondrocyte apoptosis via receptor for advanced glycation end products-mediated, redox-dependent intrinsic apoptosis pathway. Apoptosis : An International Journal On Programmed Cell Death. PMID 26520447 DOI: 10.1007/s10495-015-1191-4  0.96
2015 Yang L, Song T, Chen L, Soliman H, Chen J. Nucleolar repression facilitates initiation and maintenance of senescence. Cell Cycle (Georgetown, Tex.). 0. PMID 26505814 DOI: 10.1080/15384101.2015.1100777  0.72
2015 Chen J, Wang N, Dong M, Guo M, Zhao Y, Zhuo Z, Zhang C, Chi X, Pan Y, Jiang J, Tang H, Niu J, Yang D, Li Z, Han X, et al. The metabolic regulator histone deacetylase 9 contributes to glucose homeostasis abnormality induced by hepatitis C virus infection. Diabetes. PMID 26420860 DOI: 10.2337/db15-0197  0.96
2015 Pan Y, He B, Chen J, Sun H, Deng Q, Wang F, Ying H, Liu X, Lin K, Peng H, Xie H, Wang S. Gene therapy for colorectal cancer by adenovirus-mediated siRNA targeting CD147 based on loss of the IGF2 imprinting system. International Journal of Oncology. PMID 26397886 DOI: 10.3892/ijo.2015.3181  0.96
2015 Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, ... ... Chen JW, et al. Myeloperoxidase Nuclear Imaging for Epileptogenesis. Radiology. 141922. PMID 26397127 DOI: 10.1148/radiol.2015141922  0.96
2015 Adamczyk L, Adkins JK, Agakishiev G, Aggarwal MM, Ahammed Z, Alekseev I, Alford J, Anson CD, Aparin A, Arkhipkin D, Aschenauer EC, Averichev GS, Banerjee A, Beavis DR, Bellwied R, ... ... Chen JH, et al. Precision Measurement of the Longitudinal Double-Spin Asymmetry for Inclusive Jet Production in Polarized Proton Collisions at sqrt[s]=200  GeV. Physical Review Letters. 115: 092002. PMID 26371644  0.32
2015 Chen J, Pan Y, He B, Ying H, Wang F, Sun H, Deng Q, Liu X, Lin K, Peng H, Cho WC, Wang S. Inhibition of CD147 expression by RNA interference reduces proliferation, invasion and increases chemosensitivity in cancer stem cell-like HT-29 cells. International Journal of Oncology. PMID 26316167 DOI: 10.3892/ijo.2015.3138  0.96
2015 Zhao Y, Chan JF, Tsang CC, Wang H, Guo D, Pan Y, Xiao Y, Yue N, Chen JH, Lau SK, Xu Y, Woo PC. Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study. Journal of Clinical Microbiology. PMID 26311865 DOI: 10.1128/JCM.01985-15  0.96
2015 Wu Q, Zhong ZM, Pan Y, Zeng JH, Zheng S, Zhu SY, Chen JT. Advanced Oxidation Protein Products as a Novel Marker of Oxidative Stress in Postmenopausal Osteoporosis. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 21: 2428-32. PMID 26286507 DOI: 10.12659/MSM.894347  0.96
2015 Davies J, Chen J, Pink R, Carter D, Saunders N, Sotiriadis G, Bai B, Pan Y, Howlett D, Payne A, Randeva H, Karteris E. Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103. Scientific Reports. 5: 12584. PMID 26223541 DOI: 10.1038/srep12584  0.96
2015 Zhang HL, Zheng YJ, Pan YD, Xie C, Sun H, Zhang YH, Yuan MY, Song BL, Chen JF. Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity. Mucosal Immunology. PMID 26220167 DOI: 10.1038/mi.2015.68  0.32
2015 Chen J, Deng Q, Pan Y, He B, Ying H, Sun H, Liu X, Wang S. Prognostic value of neutrophil-to-lymphocyte ratio in breast cancer. Febs Open Bio. 5: 502-7. PMID 26137435 DOI: 10.1016/j.fob.2015.05.003  0.96
2015 Pan Y, Shao C, Wang X, Zhu Y, Chen J, Chen W, Ma S, Liu J. [Genomic characteristics of an echovirus 20 strain (KM/EV20/2010) isolated in Kunming, Yunnan, China]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi. 36: 501-5. PMID 26080642  0.96
2015 Ying HQ, Chen J, He BS, Pan YQ, Wang F, Deng QW, Sun HL, Liu X, Wang SK. The effect of BIM deletion polymorphism on intrinsic resistance and clinical outcome of cancer patient with kinase inhibitor therapy. Scientific Reports. 5: 11348. PMID 26076815 DOI: 10.1038/srep11348  0.32
2015 Chen A, Huang X, Xue Z, Cao D, Huang K, Chen J, Pan Y, Gao Y. The Role of p21 in Apoptosis, Proliferation, Cell Cycle Arrest, and Antioxidant Activity in UVB-Irradiated Human HaCaT Keratinocytes. Medical Science Monitor Basic Research. 21: 86-95. PMID 25925725 DOI: 10.12659/MSMBR.893608  0.96
2015 Deng Q, He B, Liu X, Yue J, Ying H, Pan Y, Sun H, Chen J, Wang F, Gao T, Zhang L, Wang S. Prognostic value of pre-operative inflammatory response biomarkers in gastric cancer patients and the construction of a predictive model. Journal of Translational Medicine. 13: 66. PMID 25885254 DOI: 10.1186/s12967-015-0409-0  0.96
2015 Sun L, Kokura K, Izumi V, Koomen JM, Seto E, Chen J, Fang J. MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition. Embo Reports. 16: 689-99. PMID 25870236 DOI: 10.15252/embr.201439792  0.52
2015 Ma S, Zhang Y, Du C, Yang T, Liu Q, Pan Y, Chen J, Shi H, Sun Q, Liu L, Li Q. Dynamic constitution of the pathogens inducing encephalitis in hand, foot and mouth disease in Kunming, 2009-2011. Japanese Journal of Infectious Diseases. PMID 25866107 DOI: 10.7883/yoken.JJID.2014.428  0.96
2015 Pan Y, Zhang H, Chen J, Han B, Shen Z, Lu J, Ni X. Millisecond laser machining of transparent materials assisted by nanosecond laser. Optics Express. 23: 765-75. PMID 25835836  0.96
2015 Chen L, Borcherds W, Wu S, Becker A, Schonbrunn E, Daughdrill GW, Chen J. Autoinhibition of MDMX by intramolecular p53 mimicry. Proceedings of the National Academy of Sciences of the United States of America. 112: 4624-9. PMID 25825738 DOI: 10.1073/pnas.1420833112  1
2015 Zhou Z, Su Y, Campbell B, Zhou Z, Gao J, Yu Q, Chen J, Pan Y. The financial impact of the 'zero-markup policy for essential drugs' on patients in county hospitals in western rural China. Plos One. 10: e0121630. PMID 25790443 DOI: 10.1371/journal.pone.0121630  0.96
2015 Sun H, Deng Q, Pan Y, He B, Ying H, Chen J, Liu X, Wang S. Association between estrogen receptor 1 (ESR1) genetic variations and cancer risk: a meta-analysis. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 20: 296-308. PMID 25778331  0.96
2015 Peng L, Yuan Z, Li Y, Ling H, Izumi V, Fang B, Fukasawa K, Koomen J, Chen J, Seto E. Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival. The Journal of Biological Chemistry. 290: 8904-12. PMID 25670865 DOI: 10.1074/jbc.M114.612796  0.32
2014 Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, ... ... Chen J, et al. HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. Molecular Cell. 55: 31-46. PMID 24882211 DOI: 10.1016/j.molcel.2014.04.028  0.92
2014 Cheng Q, Song T, Chen L, Chen J. Autoactivation of the MDM2 E3 ligase by intramolecular interaction. Molecular and Cellular Biology. 34: 2800-10. PMID 24842904 DOI: 10.1128/MCB.00246-14  0.72
2014 Schneeberger VE, Luetteke N, Ren Y, Berns H, Chen L, Foroutan P, Martinez GV, Haura EB, Chen J, Coppola D, Wu J. SHP2E76K mutant promotes lung tumorigenesis in transgenic mice. Carcinogenesis. 35: 1717-25. PMID 24480804 DOI: 10.1093/carcin/bgu025  1
2014 Jin L, Chen J, Li L, Li C, Chen C, Li S. CRH suppressed TGFβ1-induced Epithelial-Mesenchymal Transition via induction of E-cadherin in breast cancer cells. Cellular Signalling. 26: 757-65. PMID 24412750 DOI: 10.1016/j.cellsig.2013.12.017  0.32
2013 Zheng H, Yang L, Peng L, Izumi V, Koomen J, Seto E, Chen J. hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1. Molecular and Cellular Biology. 33: 4960-70. PMID 24126058 DOI: 10.1128/MCB.00874-13  1
2013 Yang L, Song T, Chen L, Kabra N, Zheng H, Koomen J, Seto E, Chen J. Regulation of SirT1-nucleomethylin binding by rRNA coordinates ribosome biogenesis with nutrient availability. Molecular and Cellular Biology. 33: 3835-48. PMID 23897426 DOI: 10.1128/MCB.00476-13  1
2013 Song T, Yang L, Kabra N, Chen L, Koomen J, Haura EB, Chen J. The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. The Journal of Biological Chemistry. 288: 20908-17. PMID 23737528 DOI: 10.1074/jbc.M113.470302  1
2013 Hodul PJ, Dong Y, Husain K, Pimiento JM, Chen J, Zhang A, Francois R, Pledger WJ, Coppola D, Sebti SM, Chen DT, Malafa MP. Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. Plos One. 8: e52526. PMID 23393547 DOI: 10.1371/journal.pone.0052526  0.44
2012 Wu S, Chen L, Becker A, Schonbrunn E, Chen J. Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding. Molecular and Cellular Biology. 32: 4821-32. PMID 23028042 DOI: 10.1128/MCB.00851-12  0.72
2012 Peng L, Ling H, Yuan Z, Fang B, Bloom G, Fukasawa K, Koomen J, Chen J, Lane WS, Seto E. SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. Molecular and Cellular Biology. 32: 2823-36. PMID 22586264 DOI: 10.1128/MCB.00496-12  1
2012 Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL. Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. Journal of Molecular Medicine (Berlin, Germany). 90: 803-15. PMID 22231744 DOI: 10.1007/s00109-011-0855-y  1
2012 Zhang H, Wong CC, Wei H, Gilkes DM, Korangath P, Chaturvedi P, Schito L, Chen J, Krishnamachary B, Winnard PT, Raman V, Zhen L, Mitzner WA, Sukumar S, Semenza GL. HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. Oncogene. 31: 1757-70. PMID 21860410 DOI: 10.1038/onc.2011.365  1
2011 Cheng Q, Cross B, Li B, Chen L, Li Z, Chen J. Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage. Molecular and Cellular Biology. 31: 4951-63. PMID 21986495 DOI: 10.1128/MCB.05553-11  0.72
2011 Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Molecular and Cellular Biology. 31: 4720-34. PMID 21947282 DOI: 10.1128/MCB.06147-11  1
2011 Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 16369-74. PMID 21911388 DOI: 10.1073/pnas.1113483108  1
2011 Cross B, Chen L, Cheng Q, Li B, Yuan ZM, Chen J. Inhibition of p53 DNA binding function by the MDM2 protein acidic domain. The Journal of Biological Chemistry. 286: 16018-29. PMID 21454483 DOI: 10.1074/jbc.M111.228981  0.72
2011 Hu Y, Li X, Sebti SM, Chen J, Cai J. Design and synthesis of AApeptides: a new class of peptide mimics. Bioorganic & Medicinal Chemistry Letters. 21: 1469-71. PMID 21292484 DOI: 10.1016/j.bmcl.2011.01.005  1
2011 Madden MM, Muppidi A, Li Z, Li X, Chen J, Lin Q. Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition. Bioorganic & Medicinal Chemistry Letters. 21: 1472-5. PMID 21277201 DOI: 10.1016/j.bmcl.2011.01.004  1
2011 Shen J, Zhang S, Li Y, Zhang W, Chen J, Zhang M, Wang T, Jiang L, Zou X, Wong J, Li X, Cui Y, Wang C. p14(ARF) inhibits the functions of adenovirus E1A oncoprotein. The Biochemical Journal. 434: 275-85. PMID 21133853 DOI: 10.1042/BJ20101163  0.92
2010 Chen L, Li Z, Zwolinska AK, Smith MA, Cross B, Koomen J, Yuan ZM, Jenuwein T, Marine JC, Wright KL, Chen J. MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output. The Embo Journal. 29: 2538-52. PMID 20588255 DOI: 10.1038/emboj.2010.140  1
2010 Li C, Pazgier M, Li J, Li C, Liu M, Zou G, Li Z, Chen J, Tarasov SG, Lu WY, Lu W. Limitations of peptide retro-inverso isomerization in molecular mimicry. The Journal of Biological Chemistry. 285: 19572-81. PMID 20382735 DOI: 10.1074/jbc.M110.116814  0.52
2010 Li B, Cheng Q, Li Z, Chen J. p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors. Cell Cycle (Georgetown, Tex.). 9: 1411-20. PMID 20372076  0.52
2010 Yuan Z, Villagra A, Peng L, Coppola D, Glozak M, Sotomayor EM, Chen J, Lane WS, Seto E. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Molecular and Cellular Biology. 30: 3004-15. PMID 20368352 DOI: 10.1128/MCB.01023-09  1
2010 Zhang Y, Dong H, Li Z, Xiang S, Zhu Y, Zhang M, Liu J, Bai W, Nicosia SV, Chen J, Zhao RJ, Zhang X. Bing De Ling, a Chinese herbal formula, inhibits cancer cells growth via p53. Frontiers in Bioscience (Elite Edition). 2: 221-30. PMID 20036872  1
2010 Phan J, Li Z, Kasprzak A, Li B, Sebti S, Guida W, Schönbrunn E, Chen J. Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX. The Journal of Biological Chemistry. 285: 2174-83. PMID 19910468 DOI: 10.1074/jbc.M109.073056  1
2009 Cheng Q, Chen L, Li Z, Lane WS, Chen J. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity. The Embo Journal. 28: 3857-67. PMID 19816404 DOI: 10.1038/emboj.2009.294  0.72
2009 Lawrence HR, Li Z, Yip ML, Sung SS, Lawrence NJ, McLaughlin ML, McManus GJ, Zaworotko MJ, Sebti SM, Chen J, Guida WC. Identification of a disruptor of the MDM2-p53 protein-protein interaction facilitated by high-throughput in silico docking. Bioorganic & Medicinal Chemistry Letters. 19: 3756-9. PMID 19457663 DOI: 10.1016/j.bmcl.2009.04.124  1
2009 Kabra N, Li Z, Chen L, Li B, Zhang X, Wang C, Yeatman T, Coppola D, Chen J. SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. The Journal of Biological Chemistry. 284: 18210-7. PMID 19433578 DOI: 10.1074/jbc.M109.000034  1
2009 Shaginian A, Whitby LR, Hong S, Hwang I, Farooqi B, Searcey M, Chen J, Vogt PK, Boger DL. Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions. Journal of the American Chemical Society. 131: 5564-72. PMID 19334711 DOI: 10.1021/ja810025g  1
2009 Fu W, Ma Q, Chen L, Li P, Zhang M, Ramamoorthy S, Nawaz Z, Shimojima T, Wang H, Yang Y, Shen Z, Zhang Y, Zhang X, Nicosia SV, Zhang Y, ... ... Chen J, et al. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation. The Journal of Biological Chemistry. 284: 13987-4000. PMID 19321440 DOI: 10.1074/jbc.M901758200  1
2009 Yamaguchi H, Woods NT, Piluso LG, Lee HH, Chen J, Bhalla KN, Monteiro A, Liu X, Hung MC, Wang HG. p53 acetylation is crucial for its transcription-independent proapoptotic functions. The Journal of Biological Chemistry. 284: 11171-83. PMID 19265193 DOI: 10.1074/jbc.M809268200  0.32
2009 Li Z, Chen L, Kabra N, Wang C, Fang J, Chen J. Inhibition of SUV39H1 methyltransferase activity by DBC1. The Journal of Biological Chemistry. 284: 10361-6. PMID 19218236 DOI: 10.1074/jbc.M900956200  1
2008 Yang W, Dicker DT, Chen J, El-Deiry WS. CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2. Cell Cycle (Georgetown, Tex.). 7: 670-82. PMID 18382127  1
2008 Gilkes DM, Pan Y, Coppola D, Yeatman T, Reuther GW, Chen J. Regulation of MDMX expression by mitogenic signaling. Molecular and Cellular Biology. 28: 1999-2010. PMID 18172009 DOI: 10.1128/MCB.01633-07  1
2007 Yang Y, Fu W, Chen J, Olashaw N, Zhang X, Nicosia SV, Bhalla K, Bai W. SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress. Nature Cell Biology. 9: 1253-62. PMID 17934453 DOI: 10.1038/ncb1645  1
2007 Hu B, Gilkes DM, Chen J. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX. Cancer Research. 67: 8810-7. PMID 17875722 DOI: 10.1158/0008-5472.CAN-07-1140  1
2007 Wang C, Rauscher FJ, Cress WD, Chen J. Regulation of E2F1 function by the nuclear corepressor KAP1. The Journal of Biological Chemistry. 282: 29902-9. PMID 17704056 DOI: 10.1074/jbc.M704757200  1
2007 Gilkes DM, Chen J. Distinct roles of MDMX in the regulation of p53 response to ribosomal stress. Cell Cycle (Georgetown, Tex.). 6: 151-5. PMID 17327702  1
2006 Gilkes DM, Chen L, Chen J. MDMX regulation of p53 response to ribosomal stress. The Embo Journal. 25: 5614-25. PMID 17110929 DOI: 10.1038/sj.emboj.7601424  1
2006 Hu B, Gilkes DM, Farooqi B, Sebti SM, Chen J. MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin. The Journal of Biological Chemistry. 281: 33030-5. PMID 16905541 DOI: 10.1074/jbc.C600147200  1
2006 Wang C, Chen L, Hou X, Li Z, Kabra N, Ma Y, Nemoto S, Finkel T, Gu W, Cress WD, Chen J. Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nature Cell Biology. 8: 1025-31. PMID 16892051 DOI: 10.1038/ncb1468  1
2006 LeBron C, Chen L, Gilkes DM, Chen J. Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. The Embo Journal. 25: 1196-206. PMID 16511560 DOI: 10.1038/sj.emboj.7601032  1
2005 Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen J, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 127: 13271-80. PMID 16173757 DOI: 10.1021/ja052733v  1
2005 Chen L, Gilkes DM, Pan Y, Lane WS, Chen J. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage. The Embo Journal. 24: 3411-22. PMID 16163388 DOI: 10.1038/sj.emboj.7600812  1
2005 Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ, Chen J. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. The Embo Journal. 24: 3279-90. PMID 16107876 DOI: 10.1038/sj.emboj.7600791  1
2005 Chen L, Li C, Pan Y, Chen J. Regulation of p53-MDMX interaction by casein kinase 1 alpha. Molecular and Cellular Biology. 25: 6509-20. PMID 16024788 DOI: 10.1128/MCB.25.15.6509-6520.2005  0.96
2005 Chen L, Yin H, Farooqi B, Sebti S, Hamilton AD, Chen J. p53 alpha-Helix mimetics antagonize p53/MDM2 interaction and activate p53. Molecular Cancer Therapeutics. 4: 1019-25. PMID 15956260 DOI: 10.1158/1535-7163.MCT-04-0342  0.72
2005 Pan Y, Chen J. Modification of MDMX by sumoylation. Biochemical and Biophysical Research Communications. 332: 702-9. PMID 15907800 DOI: 10.1016/j.bbrc.2005.05.012  0.96
2005 Wang C, Hou X, Mohapatra S, Ma Y, Cress WD, Pledger WJ, Chen J. Activation of p27Kip1 Expression by E2F1. A negative feedback mechanism. The Journal of Biological Chemistry. 280: 12339-43. PMID 15713665 DOI: 10.1074/jbc.C400536200  1
2004 Liu Q, Kaneko S, Yang L, Feldman RI, Nicosia SV, Chen J, Cheng JQ. Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. The Journal of Biological Chemistry. 279: 52175-82. PMID 15469940 DOI: 10.1074/jbc.M406802200  1
2004 Wang JW, Gamsby JJ, Highfill SL, Mora LB, Bloom GC, Yeatman TJ, Pan TC, Ramne AL, Chodosh LA, Cress WD, Chen J, Kerr WG. Deregulated expression of LRBA facilitates cancer cell growth. Oncogene. 23: 4089-97. PMID 15064745 DOI: 10.1038/sj.onc.1207567  1
2003 Chen L, Chen J. MDM2-ARF complex regulates p53 sumoylation. Oncogene. 22: 5348-57. PMID 12917636 DOI: 10.1038/sj.onc.1206851  0.72
2003 Peng Y, Li C, Chen L, Sebti S, Chen J. Rescue of mutant p53 transcription function by ellipticine. Oncogene. 22: 4478-87. PMID 12881704 DOI: 10.1038/sj.onc.1206777  0.72
2003 Pan Y, Chen J. MDM2 promotes ubiquitination and degradation of MDMX. Molecular and Cellular Biology. 23: 5113-21. PMID 12860999  0.96
2003 Wang C, Chen J. Phosphorylation and hsp90 binding mediate heat shock stabilization of p53. The Journal of Biological Chemistry. 278: 2066-71. PMID 12427754 DOI: 10.1074/jbc.M206697200  0.92
2002 Li C, Chen L, Chen J. DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms. Molecular and Cellular Biology. 22: 7562-71. PMID 12370303  0.72
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