Moshe Oren - Publications

Affiliations: 
MCB Molecular Cell Biology Weizmann Institute of Science, Rehovot, Israel 
Area:
Molecular Biology

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kotler E, Segal E, Oren M. Functional characterization of the p53 "mutome". Molecular & Cellular Oncology. 5: e1511207. PMID 30525089 DOI: 10.1080/23723556.2018.1511207  0.4
2018 Kotler E, Shani O, Goldfeld G, Lotan-Pompan M, Tarcic O, Gershoni A, Hopf TA, Marks DS, Oren M, Segal E. A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation. Molecular Cell. 71: 873. PMID 30193102 DOI: 10.1016/j.molcel.2018.08.013  0.4
2018 Kotler E, Shani O, Goldfeld G, Lotan-Pompan M, Tarcic O, Gershoni A, Hopf TA, Marks DS, Oren M, Segal E. A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation. Molecular Cell. 71: 178-190.e8. PMID 29979965 DOI: 10.1016/j.molcel.2018.06.012  0.4
2017 Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, ... ... Oren M, et al. Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & Development. 31: 1926. PMID 29051390 DOI: 10.1101/gad.307207.117  0.64
2016 Bublik DR, Bursać S, Sheffer M, Oršolić I, Shalit T, Tarcic O, Kotler E, Mouhadeb O, Hoffman Y, Fuchs G, Levin Y, Volarević S, Oren M. Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 27994142 DOI: 10.1073/pnas.1614876114  0.48
2016 Yaeger R, Shah MA, Miller VA, Kelsen JR, Wang K, Heins ZJ, Ross JS, He Y, Sanford E, Yantiss RK, Balasubramanian S, Stephens PJ, Schultz N, Oren M, Tang L, et al. Genomic Alterations Observed in Colitis-associated Cancers are Distinct from Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. Gastroenterology. PMID 27063727 DOI: 10.1053/j.gastro.2016.04.001  1
2016 Aylon Y, Gershoni A, Rotkopf R, Biton IE, Porat Z, Koh AP, Sun X, Lee Y, Fiel MI, Hoshida Y, Friedman SL, Johnson RL, Oren M. The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation. Genes & Development. PMID 27013235 DOI: 10.1101/gad.274167.115  1
2016 Tal P, Eizenberger S, Cohen E, Goldfinger N, Pietrokovski S, Oren M, Rotter V. Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides. Oncotarget. PMID 26943582 DOI: 10.18632/oncotarget.7857  1
2016 Hoffman Y, Bublik DR, P Ugalde A, Elkon R, Biniashvili T, Agami R, Oren M, Pilpel Y. 3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells. Plos Genetics. 12: e1005879. PMID 26908102 DOI: 10.1371/journal.pgen.1005879  1
2016 Tarcic O, Pateras IS, Cooks T, Shema E, Kanterman J, Ashkenazi H, Boocholez H, Hubert A, Rotkopf R, Baniyash M, Pikarsky E, Gorgoulis VG, Oren M. RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer. Cell Reports. PMID 26854224 DOI: 10.1016/j.celrep.2016.01.020  1
2015 Furth N, Bossel Ben-Moshe N, Pozniak Y, Porat Z, Geiger T, Domany E, Aylon Y, Oren M. Down-regulation of LATS kinases alters p53 to promote cell migration. Genes & Development. 29: 2325-30. PMID 26588988 DOI: 10.1101/gad.268185.115  0.48
2015 Oren M, Damalas A, Gottlieb T, Michael D, Taplick J, Martinez Leal JF, Maya R, Moas M, Seger R, Taya Y, Ben-Ze'ev A. Retraction notice to "Regulation of p53: Intricate loops and delicate balances" [Biochem. Pharmacol. 64 (2002) 865-871]. Biochemical Pharmacology. 96: 369. PMID 26465018 DOI: 10.1016/j.bcp.2015.07.001  1
2015 Fuchs G, Voichek Y, Rabani M, Benjamin S, Gilad S, Amit I, Oren M. Simultaneous measurement of genome-wide transcription elongation speeds and rates of RNA polymerase II transition into active elongation with 4sUDRB-seq. Nature Protocols. 10: 605-18. PMID 25811895 DOI: 10.1038/nprot.2015.035  1
2015 Adi Harel S, Bossel Ben-Moshe N, Aylon Y, Bublik DR, Moskovits N, Toperoff G, Azaiza D, Biagoni F, Fuchs G, Wilder S, Hellman A, Blandino G, Domany E, Oren M. Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth. Cell Death and Differentiation. 22: 1328-40. PMID 25591738 DOI: 10.1038/cdd.2014.221  1
2014 Fuchs G, Hollander D, Voichek Y, Ast G, Oren M. Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate. Genome Research. 24: 1572-83. PMID 25049226 DOI: 10.1101/gr.176487.114  1
2014 Cooks T, Harris CC, Oren M. Caught in the cross fire: p53 in inflammation. Carcinogenesis. 35: 1680-90. PMID 24942866 DOI: 10.1093/carcin/bgu134  1
2014 Hoffman Y, Pilpel Y, Oren M. microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network. Journal of Molecular Cell Biology. 6: 192-7. PMID 24868102 DOI: 10.1093/jmcb/mju020  1
2014 Golomb L, Volarevic S, Oren M. p53 and ribosome biogenesis stress: the essentials. Febs Letters. 588: 2571-9. PMID 24747423 DOI: 10.1016/j.febslet.2014.04.014  1
2014 Fuchs G, Oren M. Writing and reading H2B monoubiquitylation. Biochimica Et Biophysica Acta. 1839: 694-701. PMID 24412854 DOI: 10.1016/j.bbagrm.2014.01.002  1
2014 Oren M, Aylon Y. The hippo signaling pathway and cancer The Hippo Signaling Pathway and Cancer. 1-354. DOI: 10.1007/978-1-4614-6220-0  1
2013 Golomb L, Oren M. In the race for protection, ARF comes second Cell Death and Differentiation. 20: 1442-1443. PMID 24096933 DOI: 10.1038/cdd.2013.117  1
2013 Shema-Yaacoby E, Nikolov M, Haj-Yahya M, Siman P, Allemand E, Yamaguchi Y, Muchardt C, Urlaub H, Brik A, Oren M, Fischle W. Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Reports. 4: 601-8. PMID 23933260 DOI: 10.1016/j.celrep.2013.07.014  1
2013 Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, ... ... Oren M, et al. A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism. Cancer Cell. 24: 242-56. PMID 23890787 DOI: 10.1016/j.ccr.2013.06.005  1
2013 Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Rozenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, ... ... Oren M, et al. Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. Cancer Cell. 23: 634-46. PMID 23680148 DOI: 10.1016/j.ccr.2013.03.022  1
2013 Hoffman Y, Dahary D, Bublik DR, Oren M, Pilpel Y. The majority of endogenous microRNA targets within Alu elements avoid the microRNA machinery. Bioinformatics (Oxford, England). 29: 894-902. PMID 23361327 DOI: 10.1093/bioinformatics/btt044  1
2013 Gutekunst M, Mueller T, Weilbacher A, Dengler MA, Bedke J, Kruck S, Oren M, Aulitzky WE, van der Kuip H. Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4. Cancer Research. 73: 1460-9. PMID 23302226 DOI: 10.1158/0008-5472.CAN-12-2876  1
2012 Bursać S, Brdovčak MC, Pfannkuchen M, Orsolić I, Golomb L, Zhu Y, Katz C, Daftuar L, Grabušić K, Vukelić I, Filić V, Oren M, Prives C, Volarevic S. Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress. Proceedings of the National Academy of Sciences of the United States of America. 109: 20467-72. PMID 23169665 DOI: 10.1073/pnas.1218535109  1
2012 Haj-Yahya M, Eltarteer N, Ohayon S, Shema E, Kotler E, Oren M, Brik A. N-methylation of isopeptide bond as a strategy to resist deubiquitinases. Angewandte Chemie (International Ed. in English). 51: 11535-9. PMID 23065695 DOI: 10.1002/anie.201205771  1
2012 Schmid JO, Dong M, Haubeiss S, Friedel G, Bode S, Grabner A, Ott G, Mürdter TE, Oren M, Aulitzky WE, van der Kuip H. Cancer cells cue the p53 response of cancer-associated fibroblasts to cisplatin. Cancer Research. 72: 5824-32. PMID 22962266 DOI: 10.1158/0008-5472.CAN-12-1201  1
2012 Hornung G, Bar-Ziv R, Rosin D, Tokuriki N, Tawfik DS, Oren M, Barkai N. Noise-mean relationship in mutated promoters. Genome Research. 22: 2409-17. PMID 22820945 DOI: 10.1101/gr.139378.112  1
2012 Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M, Feldmesser E, Brik A, Yu X, Hanna J, Aberdam D, ... ... Oren M, et al. RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Molecular Cell. 46: 662-73. PMID 22681888 DOI: 10.1016/j.molcel.2012.05.023  1
2012 Hornung G, Oren M, Barkai N. Nucleosome organization affects the sensitivity of gene expression to promoter mutations. Molecular Cell. 46: 362-8. PMID 22464732 DOI: 10.1016/j.molcel.2012.02.019  1
2012 Bublik DR, Oren M. Get your fingers out of p53's way! Embo Reports. 13: 282-3. PMID 22422000 DOI: 10.1038/embor.2012.33  1
2012 Zwang Y, Oren M, Yarden Y. Consistency test of the cell cycle: roles for p53 and EGR1. Cancer Research. 72: 1051-4. PMID 22315347 DOI: 10.1158/0008-5472.CAN-11-3382  1
2012 Golomb L, Bublik DR, Wilder S, Nevo R, Kiss V, Grabusic K, Volarevic S, Oren M. Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis. Molecular Cell. 45: 222-32. PMID 22284678 DOI: 10.1016/j.molcel.2011.11.022  1
2011 Furth N, Oren M. An Aurora A-Lats-Aurora B axis ensures proper chromosome segregation. Cell Cycle (Georgetown, Tex.). 10: 3055. PMID 21908979 DOI: 10.4161/cc.10.18.16999  1
2011 Golomb L, Oren M. DePICTing p53 activation: a new nucleolar link to cancer. Cancer Cell. 20: 283-4. PMID 21907918 DOI: 10.1016/j.ccr.2011.08.017  1
2011 Aylon Y, Oren M. p53: guardian of ploidy. Molecular Oncology. 5: 315-23. PMID 21852209 DOI: 10.1016/j.molonc.2011.07.007  1
2011 Shiloh Y, Shema E, Moyal L, Oren M. RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response. Febs Letters. 585: 2795-802. PMID 21827756 DOI: 10.1016/j.febslet.2011.07.034  0.32
2011 Rivlin N, Brosh R, Oren M, Rotter V. Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis. Genes & Cancer. 2: 466-74. PMID 21779514 DOI: 10.1177/1947601911408889  1
2011 Zwang Y, Sas-Chen A, Drier Y, Shay T, Avraham R, Lauriola M, Shema E, Lidor-Nili E, Jacob-Hirsch J, Amariglio N, Lu Y, Mills GB, Rechavi G, Oren M, Domany E, et al. Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Molecular Cell. 42: 524-35. PMID 21596316 DOI: 10.1016/j.molcel.2011.04.017  0.32
2011 Shema E, Kim J, Roeder RG, Oren M. RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. Molecular Cell. 42: 477-88. PMID 21596312 DOI: 10.1016/j.molcel.2011.03.011  1
2011 Shema E, Oren M, Minsky N. Detection and characterization of ubiquitylated H2B in mammalian cells. Methods (San Diego, Calif.). 54: 326-30. PMID 21439383 DOI: 10.1016/j.ymeth.2011.03.005  0.32
2011 Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, ... ... Oren M, et al. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Molecular Cell. 41: 529-42. PMID 21362549 DOI: 10.1016/j.molcel.2011.02.015  1
2011 Dell'Orso S, Fontemaggi G, Stambolsky P, Goeman F, Voellenkle C, Levrero M, Strano S, Rotter V, Oren M, Blandino G. ChIP-on-chip analysis of in vivo mutant p53 binding to selected gene promoters. Omics : a Journal of Integrative Biology. 15: 305-12. PMID 21332394 DOI: 10.1089/omi.2010.0084  1
2011 Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y. CKIα ablation highlights a critical role for p53 in invasiveness control. Nature. 470: 409-13. PMID 21331045 DOI: 10.1038/nature09673  1
2011 Aylon Y, Oren M. New plays in the p53 theater. Current Opinion in Genetics & Development. 21: 86-92. PMID 21317061 DOI: 10.1016/j.gde.2010.10.002  1
2010 Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, Lu X, Oren M. The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1. Genes & Development. 24: 2420-9. PMID 21041410 DOI: 10.1101/gad.1954410  1
2010 Addadi Y, Moskovits N, Granot D, Lozano G, Carmi Y, Apte RN, Neeman M, Oren M. p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner Cancer Research. 70: 9650-9658. PMID 20952507 DOI: 10.1158/0008-5472.CAN-10-1146  1
2010 Lidor Nili E, Field Y, Lubling Y, Widom J, Oren M, Segal E. p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Research. 20: 1361-8. PMID 20716666 DOI: 10.1101/gr.103945.109  1
2010 Shalgi R, Pilpel Y, Oren M. Repression of transposable-elements - a microRNA anti-cancer defense mechanism? Trends in Genetics : Tig. 26: 253-9. PMID 20417576 DOI: 10.1016/j.tig.2010.03.006  1
2010 Oren M, Cooks T. NFκB and p53: A life and death affair. Cell Cycle (Georgetown, Tex.). 9: 1027. PMID 20237416  1
2010 Stambolsky P, Tabach Y, Fontemaggi G, Weisz L, Maor-Aloni R, Siegfried Z, Sigfried Z, Shiff I, Kogan I, Shay M, Kalo E, Blandino G, Simon I, Oren M, Rotter V. Modulation of the vitamin D3 response by cancer-associated mutant p53. Cancer Cell. 17: 273-85. PMID 20227041 DOI: 10.1016/j.ccr.2009.11.025  1
2010 Oren M, Rotter V. Mutant p53 gain-of-function in cancer. Cold Spring Harbor Perspectives in Biology. 2: a001107. PMID 20182618 DOI: 10.1101/cshperspect.a001107  1
2010 Bar J, Moskovits N, Oren M. Involvement of stromal p53 in tumor-stroma interactions. Seminars in Cell & Developmental Biology. 21: 47-54. PMID 19914385 DOI: 10.1016/j.semcdb.2009.11.006  1
2009 Shalgi R, Brosh R, Oren M, Pilpel Y, Rotter V. Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate. Aging. 1: 762-70. PMID 20157565  1
2009 Lavelin I, Beer A, Kam Z, Rotter V, Oren M, Navon A, Geiger B. Discovery of novel proteasome inhibitors using a high-content cell-based screening system. Plos One. 4: e8503. PMID 20041034 DOI: 10.1371/journal.pone.0008503  1
2009 Levine AJ, Oren M. The first 30 years of p53: growing ever more complex. Nature Reviews. Cancer. 9: 749-58. PMID 19776744 DOI: 10.1038/nrc2723  1
2009 Pirngruber J, Shchebet A, Schreiber L, Shema E, Minsky N, Chapman RD, Eick D, Aylon Y, Oren M, Johnsen SA. CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing. Embo Reports. 10: 894-900. PMID 19575011 DOI: 10.1038/embor.2009.108  1
2009 Bar J, Feniger-Barish R, Lukashchuk N, Shaham H, Moskovits N, Goldfinger N, Simansky D, Perlman M, Papa M, Yosepovich A, Rechavi G, Rotter V, Oren M. Cancer cells suppress p53 in adjacent fibroblasts. Oncogene. 28: 933-6. PMID 19060923 DOI: 10.1038/onc.2008.445  1
2008 Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, ... ... Oren M, et al. p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation. Molecular Systems Biology. 4: 229. PMID 19034270 DOI: 10.1038/msb.2008.65  1
2008 Ofir-Rosenfeld Y, Boggs K, Michael D, Kastan MB, Oren M. Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. Molecular Cell. 32: 180-9. PMID 18951086 DOI: 10.1016/j.molcel.2008.08.031  1
2008 Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, ... ... Oren M, et al. The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & Development. 22: 2664-76. PMID 18832071 DOI: 10.1101/gad.1703008  1
2008 Minsky N, Shema E, Field Y, Schuster M, Segal E, Oren M. Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nature Cell Biology. 10: 483-8. PMID 18344985 DOI: 10.1038/ncb1712  1
2007 Raver-Shapira N, Oren M. Tiny actors, great roles: microRNAs in p53's service. Cell Cycle (Georgetown, Tex.). 6: 2656-61. PMID 17957137  1
2007 Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell. 12: 342-54. PMID 17936559 DOI: 10.1016/j.ccr.2007.08.033  1
2007 Lantner F, Starlets D, Gore Y, Flaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M, Shachar I. CD74 induces TAp63 expression leading to B-cell survival. Blood. 110: 4303-11. PMID 17846227 DOI: 10.1182/blood-2007-04-087486  1
2007 Aylon Y, Oren M. Living with p53, dying of p53. Cell. 130: 597-600. PMID 17719538 DOI: 10.1016/j.cell.2007.08.005  1
2007 Shalgi R, Lieber D, Oren M, Pilpel Y. Global and local architecture of the mammalian microRNA-transcription factor regulatory network. Plos Computational Biology. 3: e131. PMID 17630826 DOI: 10.1371/journal.pcbi.0030131  1
2007 Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, Moskovits N, Bentwich Z, Oren M. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Molecular Cell. 26: 731-43. PMID 17540598 DOI: 10.1016/j.molcel.2007.05.017  1
2007 Weisz L, Oren M, Rotter V. Transcription regulation by mutant p53 Oncogene. 26: 2202-2211. PMID 17401429 DOI: 10.1038/sj.onc.1210294  1
2007 Shmueli A, Oren M. Mdm2: p53's lifesaver? Molecular Cell. 25: 794-6. PMID 17386256 DOI: 10.1016/j.molcel.2007.03.006  1
2007 Oren M, Bartek J. The sunny side of p53. Cell. 128: 826-8. PMID 17350568 DOI: 10.1016/j.cell.2007.02.027  1
2006 Moskovits N, Kalinkovich A, Bar J, Lapidot T, Oren M. p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Research. 66: 10671-6. PMID 17108103 DOI: 10.1158/0008-5472.CAN-06-2323  1
2006 Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M. A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes & Development. 20: 2687-700. PMID 17015431 DOI: 10.1101/gad.1447006  1
2006 Reef S, Zalckvar E, Shifman O, Bialik S, Sabanay H, Oren M, Kimchi A. A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Molecular Cell. 22: 463-75. PMID 16713577 DOI: 10.1016/j.molcel.2006.04.014  1
2006 Avkin S, Sevilya Z, Toube L, Geacintov N, Chaney SG, Oren M, Livneh Z. p53 and p21 regulate error-prone DNA repair to yield a lower mutation load. Molecular Cell. 22: 407-13. PMID 16678112 DOI: 10.1016/j.molcel.2006.03.022  1
2006 Kogan I, Goldfinger N, Milyavsky M, Cohen M, Shats I, Dobler G, Klocker H, Wasylyk B, Voller M, Aalders T, Schalken JA, Oren M, Rotter V. hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis. Cancer Research. 66: 3531-40. PMID 16585177 DOI: 10.1158/0008-5472.CAN-05-2183  1
2005 Shmueli A, Oren M. Life, death, and ubiquitin: taming the mule. Cell. 121: 963-5. PMID 15989944 DOI: 10.1016/j.cell.2005.06.018  1
2005 Gressner O, Schilling T, Lorenz K, Schulze Schleithoff E, Koch A, Schulze-Bergkamen H, Lena AM, Candi E, Terrinoni A, Catani MV, Oren M, Melino G, Krammer PH, Stremmel W, Müller M. TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. The Embo Journal. 24: 2458-71. PMID 15944736 DOI: 10.1038/sj.emboj.7600708  1
2004 Weisz L, Zalcenstein A, Stambolsky P, Cohen Y, Goldfinger N, Oren M, Rotter V. Transactivation of the EGR1 gene contributes to mutant p53 gain of function. Cancer Research. 64: 8318-27. PMID 15548700 DOI: 10.1158/0008-5472.CAN-04-1145  1
2004 Minsky N, Oren M. The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression. Molecular Cell. 16: 631-9. PMID 15546622 DOI: 10.1016/j.molcel.2004.10.016  1
2004 Levina E, Oren M, Ben-Ze'ev A. Downregulation of beta-catenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics. Oncogene. 23: 4444-53. PMID 15064706 DOI: 10.1038/sj.onc.1207587  1
2004 Fiucci G, Beaucourt S, Duflaut D, Lespagnol A, Stumptner-Cuvelette P, Géant A, Buchwalter G, Tuynder M, Susini L, Lassalle JM, Wasylyk C, Wasylyk B, Oren M, Amson R, Telerman A. Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter. Proceedings of the National Academy of Sciences of the United States of America. 101: 3510-5. PMID 14985507 DOI: 10.1073/pnas.0400177101  1
2004 Bar J, Cohen-Noyman E, Geiger B, Oren M. Attenuation of the p53 response to DNA damage by high cell density. Oncogene. 23: 2128-37. PMID 14755247 DOI: 10.1038/sj.onc.1207325  1
2004 Shmueli A, Oren M. Regulation of p53 by Mdm2: fate is in the numbers. Molecular Cell. 13: 4-5. PMID 14731389 DOI: 10.1016/S1097-2765(03)00529-X  1
2003 Zalcenstein A, Stambolsky P, Weisz L, Müller M, Wallach D, Goncharov TM, Krammer PH, Rotter V, Oren M. Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene. 22: 5667-76. PMID 12944915 DOI: 10.1038/sj.onc.1206724  1
2003 Wang X, Zalcenstein A, Oren M. Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation Cell Death and Differentiation. 10: 468-476. PMID 12719724 DOI: 10.1038/sj.cdd.4401181  1
2003 Oren M. Decision making by p53: Life, death and cancer Cell Death and Differentiation. 10: 431-442. PMID 12719720 DOI: 10.1038/sj.cdd.4401183  1
2003 Passer BJ, Nancy-Portebois V, Amzallag N, Prieur S, Cans C, Roborel de Climens A, Fiucci G, Bouvard V, Tuynder M, Susini L, Morchoisne S, Crible V, Lespagnol A, Dausset J, Oren M, et al. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. Proceedings of the National Academy of Sciences of the United States of America. 100: 2284-9. PMID 12606722 DOI: 10.1073/pnas.0530298100  1
2003 Lavon I, Pikarsky E, Gutkovich E, Goldberg I, Bar J, Oren M, Ben-Neriah Y. Nuclear factor-kappaB protects the liver against genotoxic stress and functions independently of p53. Cancer Research. 63: 25-30. PMID 12517772  0.64
2003 Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Seminars in Cancer Biology. 13: 49-58. PMID 12507556 DOI: 10.1016/S1044-579X(02)00099-8  1
2002 Shtutman M, Zhurinsky J, Oren M, Levina E, Ben-Ze'ev A. PML is a target gene of beta-catenin and plakoglobin, and coactivates beta-catenin-mediated transcription. Cancer Research. 62: 5947-54. PMID 12384561  1
2002 Folberg-Blum A, Sapir A, Shilo BZ, Oren M. Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila. Oncogene. 21: 2413-7. PMID 11948425 DOI: 10.1038/sj.onc.1205305  1
2002 Michael D, Oren M. The p53 and Mdm2 families in cancer. Current Opinion in Genetics & Development. 12: 53-9. PMID 11790555 DOI: 10.1016/S0959-437X(01)00264-7  1
2001 Oren M. The p53 saga: the good, the bad, and the dead Harvey Lectures. 97: 57-82. PMID 14562517  1
2001 Oren M. Tumor suppressor perspective Experimental Cell Research. 264: 1. PMID 11237518 DOI: 10.1006/excr.2000.5147  1
2000 Maya R, Oren M. Unmasking of phosphorylation-sensitive epitopes on p53 and Mdm2 by a simple Western-phosphatase procedure Oncogene. 19: 3213-3215. PMID 10918576  1
1999 Oren M. Regulation of the p53 tumor suppressor protein Journal of Biological Chemistry. 274: 36031-36034. PMID 10593882 DOI: 10.1074/jbc.274.51.36031  1
1999 Elkeles A, Oren M. Cancer: Molecular players and unifying principles Molecular Medicine Today. 5: 334-335. PMID 10475713 DOI: 10.1016/S1357-4310(99)01526-9  1
1999 Juven-Gershon T, Oren M. MDM2: The ups and downs Molecular Medicine. 5: 71-83. PMID 10203572  1
1999 Oren M, Rotter V. Introduction. p53: The first twenty years Cellular and Molecular Life Sciences. 55: 9-11. PMID 10065147 DOI: 10.1007/s000180050265  1
1999 Blandino G, Levine AJ, Oren M. Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene. 18: 477-85. PMID 9927204 DOI: 10.1038/sj.onc.1202314  1
1998 Wang Y, Blandino G, Oren M, Givol D. Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs Oncogene. 17: 1923-1930. PMID 9788435  1
1998 Gottlieb E, Oren M. p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53 Embo Journal. 17: 3587-3596. PMID 9649429 DOI: 10.1093/emboj/17.13.3587  1
1998 Oren M. Teaming up to restrain cancer Nature. 391: 233-234. PMID 9440684 DOI: 10.1038/34551  1
1997 Gottlieb TM, Oren M. p53 and apoptosis Seminars in Cancer Biology. 8: 359-368. PMID 10101801 DOI: 10.1006/scbi.1998.0098  1
1997 Zauberman A, Oren M, Zipori D. Involvement of p21(WAF1/Cip1), CDK4 and Rb in activin A mediated signaling leading to hepatoma cell growth inhibition Oncogene. 15: 1705-1711. PMID 9349504  1
1997 Oren M. Lonely no more: P53 finds its kin in a tumor suppressor haven Cell. 90: 829-832. PMID 9298894 DOI: 10.1016/S0092-8674(00)80347-5  1
1997 Hansen R, Oren M. p53; from inductive signal to cellular effect Current Opinion in Genetics and Development. 7: 46-51. PMID 9024633 DOI: 10.1016/S0959-437X(97)80108-6  1
1996 Oren M, Prives C. p53: Upstream, downstream and off stream. Review of the 8th p53 workshop (Dundee, July 5-9, 1996) Biochimica Et Biophysica Acta - Reviews On Cancer. 1288. PMID 9011182 DOI: 10.1016/S0304-419X(96)00030-3  1
1996 Haupt Y, Oren M. p53-mediated apoptosis: mechanisms and regulation Behring Institute Mitteilungen. 32-59. PMID 8950466  1
1996 Gottlieb E, Lindner S, Oren M. Relationship of sequence-specific transactivation and p53-regulated apoptosis in interleukin 3-dependent hematopoietic cells Cell Growth and Differentiation. 7: 301-310. PMID 8838860  1
1996 Friedlander P, Haupt Y, Prives C, Oren M. A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis Molecular and Cellular Biology. 16: 4961-4971. PMID 8756655  1
1996 Gottlieb TM, Oren M. p53 in growth control and neoplasia Biochimica Et Biophysica Acta - Reviews On Cancer. 1287: 77-102. PMID 8672531 DOI: 10.1016/0304-419X(95)00019-C  1
1996 Knippschild U, Oren M, Deppert W. Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion Oncogene. 12: 1755-1765. PMID 8622896  1
1996 Haupt Y, Barak Y, Oren M. Cell type-specific inhibition of p53-mediated apoptosis by mdm2 Embo Journal. 15: 1596-1606. PMID 8612583  1
1995 Stuart ET, Haffner R, Oren M, Gruss P. Loss of p53 function through PAX-mediated transcriptional repression. The Embo Journal. 14: 5638-45. PMID 8521821  1
1995 Shaulian E, Haviv I, Shaul Y, Oren M. Transcriptional repression by the C-terminal domain of p53 Oncogene. 10: 671-680. PMID 7862444  1
1995 Zauberman A, Lupo A, Oren M. Identification of p53 target genes through immune selection of genomic DNA: The cyclin G gene contains two distinct p53 binding sites Oncogene. 10: 2361-2366. PMID 7784084  1
1995 Haffner R, Oren M. Biochemical properties and biological effects of p53 Current Opinion in Genetics and Development. 5: 84-90. PMID 7749331 DOI: 10.1016/S0959-437X(95)90058-6  1
1995 Haupt Y, Rowan S, Oren M. p53-mediated apoptosis in HeLa cells can be overcame by excess pRB Oncogene. 10: 1563-1571. PMID 7731711  1
1995 Malcomson RDG, Oren M, Wyllie AH, Harrison DJ. P53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs British Journal of Cancer. 72: 952-957. PMID 7547247 DOI: 10.1038/bjc.1995.440  1
1995 Aharoni D, Dantes A, Oren M, Amsterdam A. cAMP-mediated signals as determinants for apoptosis in primary granulosa cells Experimental Cell Research. 218: 271-282. PMID 7537693 DOI: 10.1006/excr.1995.1156  1
1994 Ciechanover A, Shkedy D, Oren M, Bercovich B. Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2 Journal of Biological Chemistry. 269: 9582-9589. PMID 8144545  1
1994 Oren M. Relationship of p53 to the control of apoptotic cell death Seminars in Cancer Biology. 5: 221-227. PMID 7948950  1
1993 Barak Y, Juven T, Haffner R, Oren M. mdm2 expression is induced by wild type p53 activity Embo Journal. 12: 461-468. PMID 8440237  1
1992 Barak Y, Oren M. Enhanced binding of a 95 kDa protein to p53 in cells undergoing p53-mediated growth arrest Embo Journal. 11: 2115-2121. PMID 1600943  1
1992 Yehiely F, Oren M. The gene for the rat heat-shock cognate, hsc70, can suppress oncogene-mediated transformation Cell Growth &Amp; Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 3: 803-809. PMID 1467307  1
1992 Shaulian E, Zauberman A, Ginsberg D, Oren M. Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding Molecular and Cellular Biology. 12: 5581-5592. PMID 1448088  1
1992 Oren M. p53: The ultimate tumor suppressor gene? Faseb Journal. 6: 3169-3176. PMID 1397838  1
1992 Oren M. The involvement of oncogenes and tumor suppressor genes in the control of apoptosis Cancer and Metastasis Review. 11: 141-148. PMID 1394793 DOI: 10.1007/BF00048060  1
1991 Michalovitz D, Halevy O, Oren M. p53 mutations: Gains or losses? Journal of Cellular Biochemistry. 45: 22-29. PMID 2005181  1
1991 Ginsberg D, Mechta F, Yaniv M, Oren M. Wild-type p53 can down-modulate the activity of various promoters Proceedings of the National Academy of Sciences of the United States of America. 88: 9979-9983. PMID 1946467  1
1991 Halevy O, Rodel J, Peled A, Oren M. Frequent p53 mutations in chemically induced murine fibrosarcoma Oncogene. 6: 1593-1600. PMID 1923526  1
1991 Eizenberg O, Oren M. Reduced levels of α1 (I) collagen mRNA in cells immortalized by mutant p53 or transformed by ras Bba - Gene Structure and Expression. 1129: 34-42. PMID 1756178 DOI: 10.1016/0167-4781(91)90209-5  1
1991 Michael-Michalovitz D, Yehiely F, Gottlieb E, Oren M. Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding Journal of Virology. 65: 4160-4168. PMID 1649323  1
1990 Halevy O, Michalovitz D, Oren M. Different tumor-derived p53 mutants exhibited distinct biological activities Science. 250: 113-116. PMID 2218501  1
1990 Ginsberg D, Oren M, Yaniv M, Piette J. Protein-binding elements in the promoter region of the mouse p53 gene Oncogene. 5: 1285-1290. PMID 2216454  1
1990 Michalovitz D, Halevy O, Oren M. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell. 62: 671-680. PMID 2143698 DOI: 10.1016/0092-8674(90)90113-S  1
1989 Michalovitz D, Amsterdam A, Oren M. Interactions between SV40 and cellular oncogenes in the transformation of primary rat cells Current Topics in Microbiology and Immunology. 144: 63-75. PMID 2551593  1
1989 Halevy O, Hall A, Oren M. Stabilization of the p53 transformation-related protein in mouse fibrosarcoma cell lines: Effects of protein sequence and intracellular environment Molecular and Cellular Biology. 9: 3385-3392. PMID 2529426  1
1988 Kraiss S, Quaiser A, Oren M, Montenarh M. Oligomerization of oncoprotein p53 Journal of Virology. 62: 4737-4744. PMID 3054153  1
1986 Kaczmarek L, Oren M, Baserga R. Co-operation between the p53 protein tumor antigen and platelet-poor plasma in the induction of cellular DNA synthesis Experimental Cell Research. 162: 268-272. PMID 3509995 DOI: 10.1016/0014-4827(86)90445-3  1
1986 Michalovitz D, Eliyahu D, Oren M. Overproduction of protein p53 contributes to simian virus 40-mediated transformation Molecular and Cellular Biology. 6: 3531-3536. PMID 3025598  1
1985 Rogel A, Popliker M, Webb CG, Oren M. p53 cellular tumor antigen: Analysis of mRNA levels in normal adult tissues, embryos, and tumors Molecular and Cellular Biology. 5: 2851-2855. PMID 3915536  1
1985 Oren M. The p53 cellular tumor antigen: gene structure, expression and protein properties Bba - Reviews On Cancer. 823: 67-78. PMID 3902087 DOI: 10.1016/0304-419X(85)90015-0  1
1985 Eliyahu D, Michalovitz D, Oren M. Overproduction of p53 antigen makes established cells highly tumorigenic Nature. 316: 158-160. PMID 3892307 DOI: 10.1038/316158a0  1
1984 Wolf D, Admon S, Oren M, Rotter V. Abelson murine leukemia virus-transformed cells that lack p53 protein synthesis express aberrant p53 mRNA species Molecular and Cellular Biology. 4: 552-558. PMID 6144042  1
1984 Pinhasi O, Oren M. Expression of the mouse p35 cellular tumor antigen in monkey cells Molecular and Cellular Biology. 4: 2180-2186. PMID 6095045  1
1983 Reich NC, Oren M, Levine AJ. Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53 Molecular and Cellular Biology. 3: 2143-2150. PMID 6318085  1
1983 Oren M, Levine AJ. Molecular cloning of a cDNA specific for the murine p53 cellular tumor antigen Proceedings of the National Academy of Sciences of the United States of America. 80: 56-59. PMID 6296874  1
1982 Robinson R, Schutzbank T, Oren M, Levine AJ. Regulation of the levels of cellular transcripts by SV40 large T antigen Annals of the New York Academy of Sciences. 397: 221-228. PMID 6297350  1
1982 Schutzbank T, Robinson R, Oren M, Levine AJ. SV40 large tumor antigen can regulate some cellular transcripts in a positive fashion Cell. 30: 481-490. PMID 6291771 DOI: 10.1016/0092-8674(82)90245-8  1
1982 Oren M, Reich NC, Levine AJ. Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny Molecular and Cellular Biology. 2: 443-449. PMID 6287239  1
1982 Levine AJ, Kaplan L, Oren M. The regulation of a cellular protein, p53, in transformed cells and its association with viral tumor antigens Hepatology. 2.  1
1981 Oren M, Levine AJ. Immunoselection of simian virus 40 large T antigen messenger RNAs from transformed cells Virology. 113: 790-793. PMID 6267809 DOI: 10.1016/0042-6822(81)90210-5  1
1981 Maltzman W, Oren M, Levine AJ. The structural relationships between 54,000-molecular-weight cellular tumor antigens detected in viral- and nonviral-transformed cells Virology. 112: 145-156. PMID 6264678 DOI: 10.1016/0042-6822(81)90620-6  1
1981 Oren M, Maltzman W, Levine AJ. Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells Molecular and Cellular Biology. 1: 101-110. PMID 6100960  1
1980 Oren M, Winocour E, Prives C. Differential affinities of simian virus 40 large tumor antigen for DNA. Proceedings of the National Academy of Sciences of the United States of America. 77: 220-4. PMID 6244545  1
1978 Oren M, Lavi S, Winocour E. The structure of a cloned substituted SV40 genome. Virology. 85: 404-21. PMID 208233 DOI: 10.1016/0042-6822(78)90448-8  1
1977 Gluzman Y, Davison J, Oren M, Winocour E. Properties of permissive monkey cells transformed by UV-irradiated simian virus 40. Journal of Virology. 22: 256-66. PMID 194053  1
1976 Oren M, Kuff EL, Winocour E. The presence of common host sequences in different populations of substituted SV40 DNA. Virology. 73: 419-30. PMID 183362 DOI: 10.1016/0042-6822(76)90403-7  1
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