Ihor R. Lemischka - Publications

Affiliations: 
Developmental and Stem Cell Biology (DSCB) Mount Sinai School of Medicine, New York, NY 
Area:
Cell Biology, Molecular Biology, Biochemistry

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Su J, Zhu D, Huo Z, Gingold JA, Ang YS, Tu J, Zhou R, Lin Y, Luo H, Yang H, Zhao R, Schaniel C, Moore KA, Lemischka IR, Lee DF. Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells. Cell Reports. 28: 1400-1409.e4. PMID 31390555 DOI: 10.1016/j.celrep.2019.07.011  0.32
2018 Kim H, Yoo S, Zhou R, Xu A, Bernitz JM, Yuan Y, Gomes AM, Daniel MG, Su J, Demicco EG, Zhu J, Moore KA, Lee DF, Lemischka IR, Schaniel C. Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 30385632 DOI: 10.1073/pnas.1814044115  0.32
2017 Freire AG, Waghray A, Soares-da-Silva F, Resende TP, Lee DF, Pereira CF, Nascimento DS, Lemischka IR, Pinto-do-Ó P. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate. Stem Cell Reports. PMID 28648899 DOI: 10.1016/j.stemcr.2017.05.025  0.32
2016 Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka IR. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nature Communications. 7: 11742. PMID 27230261 DOI: 10.1038/ncomms11742  0.36
2016 Pereira CF, Chang B, Gomes A, Bernitz J, Papatsenko D, Niu X, Swiers G, Azzoni E, de Bruijn MF, Schaniel C, Lemischka IR, Moore KA. Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells. Developmental Cell. 36: 525-39. PMID 26954547 DOI: 10.1016/j.devcel.2016.02.011  0.36
2016 Daniel MG, Lemischka IR, Moore K. Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming. Annals of the New York Academy of Sciences. PMID 26748878 DOI: 10.1111/nyas.12989  0.36
2016 Papatsenko D, Lemischka IR. Emerging Modeling Concepts and Solutions in Stem Cell Research Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.040  0.36
2015 Daniel MG, Pereira CF, Lemischka IR, Moore KA. Making a Hematopoietic Stem Cell. Trends in Cell Biology. PMID 26526106 DOI: 10.1016/j.tcb.2015.10.002  0.36
2015 Mulero-Navarro S, Sevilla A, Roman AC, Lee DF, D'Souza SL, Pardo S, Riess I, Su J, Cohen N, Schaniel C, Rodriguez NA, Baccarini A, Brown BD, Cavé H, Caye A, ... ... Lemischka IR, et al. Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia. Cell Reports. 13: 504-515. PMID 26456833 DOI: 10.1016/j.celrep.2015.09.019  0.36
2015 Papatsenko D, Darr H, Kulakovskiy IV, Waghray A, Makeev VJ, MacArthur BD, Lemischka IR. Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal. Stem Cell Reports. 5: 207-20. PMID 26267829 DOI: 10.1016/j.stemcr.2015.07.004  0.36
2015 Gingold JA, Coakley ES, Su J, Lee DF, Lau Z, Zhou H, Felsenfeld DP, Schaniel C, Lemischka IR. Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen. Bmc Bioinformatics. 16: 225. PMID 26198214 DOI: 10.1186/s12859-015-0636-7  0.36
2015 Waghray A, Saiz N, Jayaprakash AD, Freire AG, Papatsenko D, Pereira CF, Lee DF, Brosh R, Chang B, Darr H, Gingold J, Kelley K, Schaniel C, Hadjantonakis AK, Lemischka IR. Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm. Stem Cell Reports. 5: 97-110. PMID 26095607 DOI: 10.1016/j.stemcr.2015.05.009  0.36
2015 Ding J, Huang X, Shao N, Zhou H, Lee DF, Faiola F, Fidalgo M, Guallar D, Saunders A, Shliaha PV, Wang H, Waghray A, Papatsenko D, Sánchez-Priego C, Li D, ... ... Lemischka IR, et al. Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming. Cell Stem Cell. 16: 653-68. PMID 25936917 DOI: 10.1016/j.stem.2015.04.001  0.36
2015 Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR. Modeling familial cancer with induced pluripotent stem cells. Cell. 161: 240-54. PMID 25860607 DOI: 10.1016/j.cell.2015.02.045  0.36
2015 Papatsenko D, Lemischka IR. NetExplore: a web server for modeling small network motifs. Bioinformatics (Oxford, England). 31: 1860-2. PMID 25637559 DOI: 10.1093/bioinformatics/btv058  0.36
2014 Gingold JA, Fidalgo M, Guallar D, Lau Z, Sun Z, Zhou H, Faiola F, Huang X, Lee DF, Waghray A, Schaniel C, Felsenfeld DP, Lemischka IR, Wang J. A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Molecular Cell. 56: 140-52. PMID 25240402 DOI: 10.1016/j.molcel.2014.08.014  0.36
2014 Xu H, Ang YS, Sevilla A, Lemischka IR, Ma'ayan A. Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells. Plos Computational Biology. 10: e1003777. PMID 25122140 DOI: 10.1371/journal.pcbi.1003777  0.36
2014 Kim HS, Bernitz JM, Lee DF, Lemischka IR. Genomic editing tools to model human diseases with isogenic pluripotent stem cells. Stem Cells and Development. 23: 2673-86. PMID 25075441 DOI: 10.1089/scd.2014.0167  0.36
2014 Pereira CF, Lemischka IR, Moore K. 'From blood to blood': de-differentiation of hematopoietic progenitors to stem cells. The Embo Journal. 33: 1511-3. PMID 24907133 DOI: 10.15252/embj.201488980  0.36
2014 Pereira CF, Lemischka IR, Moore K. "There will be blood" from fibroblasts. Cell Cycle (Georgetown, Tex.). 13: 335-6. PMID 24335410 DOI: 10.4161/cc.27507  0.36
2014 Zhang H, Nieves JL, Fraser ST, Isern J, Douvaras P, Papatsenko D, D'Souza SL, Lemischka IR, Dyer MA, Baron MH. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells (Dayton, Ohio). 32: 191-203. PMID 24022884 DOI: 10.1002/stem.1536  0.36
2013 MacArthur BD, Lemischka IR. Statistical mechanics of pluripotency. Cell. 154: 484-9. PMID 23911316 DOI: 10.1016/j.cell.2013.07.024  0.36
2013 Zhang YS, Sevilla A, Wan LQ, Lemischka IR, Vunjak-Novakovic G. Patterning pluripotency in embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 1806-15. PMID 23843329 DOI: 10.1002/stem.1468  0.36
2013 Xu H, Baroukh C, Dannenfelser R, Chen EY, Tan CM, Kou Y, Kim YE, Lemischka IR, Ma'ayan A. ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells. Database : the Journal of Biological Databases and Curation. 2013: bat045. PMID 23794736 DOI: 10.1093/database/bat045  0.36
2013 Pereira CF, Chang B, Qiu J, Niu X, Papatsenko D, Hendry CE, Clark NR, Nomura-Kitabayashi A, Kovacic JC, Ma'ayan A, Schaniel C, Lemischka IR, Moore K. Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell. 13: 205-18. PMID 23770078 DOI: 10.1016/j.stem.2013.05.024  0.36
2013 Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S. SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics. 8: 177-83. PMID 23324626 DOI: 10.4161/epi.23416  0.36
2012 MacArthur BD, Sevilla A, Lenz M, Müller FJ, Schuldt BM, Schuppert AA, Ridden SJ, Stumpf PS, Fidalgo M, Ma'ayan A, Wang J, Lemischka IR. Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity. Nature Cell Biology. 14: 1139-47. PMID 23103910 DOI: 10.1038/ncb2603  0.36
2012 Fidalgo M, Faiola F, Pereira CF, Ding J, Saunders A, Gingold J, Schaniel C, Lemischka IR, Silva JC, Wang J. Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming. Proceedings of the National Academy of Sciences of the United States of America. 109: 16202-7. PMID 22988117 DOI: 10.1073/pnas.1208533109  0.36
2012 Pereira CF, Lemischka IR, Moore K. Reprogramming cell fates: insights from combinatorial approaches. Annals of the New York Academy of Sciences. 1266: 7-17. PMID 22901251 DOI: 10.1111/j.1749-6632.2012.06508.x  0.36
2012 Lee DF, Su J, Ang YS, Carvajal-Vergara X, Mulero-Navarro S, Pereira CF, Gingold J, Wang HL, Zhao R, Sevilla A, Darr H, Williamson AJ, Chang B, Niu X, Aguilo F, ... ... Lemischka IR, et al. Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell. 11: 179-94. PMID 22862944 DOI: 10.1016/j.stem.2012.05.020  0.36
2012 Lee DF, Su J, Sevilla A, Gingold J, Schaniel C, Lemischka IR. Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Nature Protocols. 7: 729-48. PMID 22441292 DOI: 10.1038/nprot.2012.018  0.36
2012 Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 21: 105-20. PMID 22264792 DOI: 10.1016/j.ccr.2011.12.006  0.36
2012 Sevilla A, Trinite B, Lemischka IR. Omics era in stem cell research: Data integration of multi-regulatory layers New Frontiers of Network Analysis in Systems Biology. 119-137. DOI: 10.1007/978-94-007-4330-4_7  0.36
2012 Chang B, Lemischka IR, Schaniel C. MicroRNAs in development, stem cell differentiation, and regenerative medicine Regulatory Rnas: Basics, Methods and Applications. 2147483647: 409-442. DOI: 10.1007/978-3-642-22517-8_17  0.36
2011 Schaniel C, Sirabella D, Qiu J, Niu X, Lemischka IR, Moore KA. Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells. Blood. 118: 2420-9. PMID 21652676 DOI: 10.1182/blood-2010-09-305664  0.36
2011 Ang YS, Gaspar-Maia A, Lemischka IR, Bernstein E. Stem cells and reprogramming: breaking the epigenetic barrier? Trends in Pharmacological Sciences. 32: 394-401. PMID 21621281 DOI: 10.1016/j.tips.2011.03.002  0.36
2011 Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR, Rendl M. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 29: 964-71. PMID 21563278 DOI: 10.1002/stem.649  0.36
2011 Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, Wang J, Rendl M, Bernstein E, Schaniel C, Lemischka IR. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell. 145: 183-97. PMID 21477851 DOI: 10.1016/j.cell.2011.03.003  0.36
2011 Josowitz R, Carvajal-Vergara X, Lemischka IR, Gelb BD. Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders. Current Opinion in Cardiology. 26: 223-9. PMID 21451408 DOI: 10.1097/HCO.0b013e32834598ad  0.36
2011 Green MD, Chen A, Nostro MC, d'Souza SL, Schaniel C, Lemischka IR, Gouon-Evans V, Keller G, Snoeck HW. Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nature Biotechnology. 29: 267-72. PMID 21358635 DOI: 10.1038/nbt.1788  0.36
2011 Aguilo F, Avagyan S, Labar A, Sevilla A, Lee DF, Kumar P, Lemischka IR, Zhou BY, Snoeck HW. Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood. 117: 5057-66. PMID 21343612 DOI: 10.1182/blood-2010-08-300145  0.36
2011 Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda Z, Suda T, Lemischka IR. Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2468-73. PMID 21252303 DOI: 10.1073/pnas.1003403108  0.36
2010 Markowetz F, Mulder KW, Airoldi EM, Lemischka IR, Troyanskaya OG. Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells. Plos Computational Biology. 6: e1001034. PMID 21187909 DOI: 10.1371/journal.pcbi.1001034  0.36
2010 Xu H, Lemischka IR, Ma'ayan A. SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells. Bmc Systems Biology. 4: 173. PMID 21176149 DOI: 10.1186/1752-0509-4-173  0.36
2010 Xu H, Schaniel C, Lemischka IR, Ma'ayan A. Toward a complete in silico, multi-layered embryonic stem cell regulatory network. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 708-33. PMID 20890967 DOI: 10.1002/wsbm.93  0.36
2010 Schaniel C, Lee DF, Lemischka IR. Exploration of self-renewal and pluripotency in ES cells using RNAi. Methods in Enzymology. 477: 351-65. PMID 20699150 DOI: 10.1016/S0076-6879(10)77018-X  0.36
2010 Carvajal-Vergara X, Sevilla A, D'Souza SL, Ang YS, Schaniel C, Lee DF, Yang L, Kaplan AD, Adler ED, Rozov R, Ge Y, Cohen N, Edelmann LJ, Chang B, Waghray A, ... ... Lemischka IR, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature. 465: 808-12. PMID 20535210 DOI: 10.1038/nature09005  0.36
2010 Lemischka IR. Hooking up with Oct4. Cell Stem Cell. 6: 291-2. PMID 20362529 DOI: 10.1016/j.stem.2010.03.011  0.36
2010 MacArthur BD, Lachmann A, Lemischka IR, Ma'ayan A. GATE: software for the analysis and visualization of high-dimensional time series expression data. Bioinformatics (Oxford, England). 26: 143-4. PMID 19892805 DOI: 10.1093/bioinformatics/btp628  0.36
2010 Tarleton HP, Lemischka IR. Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2. Mechanisms of Development. 127: 107-19. PMID 19825414 DOI: 10.1016/j.mod.2009.10.002  0.36
2009 Lu R, Markowetz F, Unwin RD, Leek JT, Airoldi EM, MacArthur BD, Lachmann A, Rozov R, Ma'ayan A, Boyer LA, Troyanskaya OG, Whetton AD, Lemischka IR. Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature. 462: 358-62. PMID 19924215 DOI: 10.1038/nature08575  0.36
2009 Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ. Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 2979-91. PMID 19785031 DOI: 10.1002/stem.223  0.36
2009 Macarthur BD, Ma'ayan A, Lemischka IR. Systems biology of stem cell fate and cellular reprogramming. Nature Reviews. Molecular Cell Biology. 10: 672-81. PMID 19738627 DOI: 10.1038/nrm2766  0.36
2009 Fasano CA, Phoenix TN, Kokovay E, Lowry N, Elkabetz Y, Dimos JT, Lemischka IR, Studer L, Temple S. Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes & Development. 23: 561-74. PMID 19270157 DOI: 10.1101/gad.1743709  0.36
2009 Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/j.stem.2009.02.010  0.36
2008 MacArthur BD, Ma'ayan A, Lemischka IR. Toward stem cell systems biology: from molecules to networks and landscapes. Cold Spring Harbor Symposia On Quantitative Biology. 73: 211-5. PMID 19329576 DOI: 10.1101/sqb.2008.73.061  0.36
2008 Guan Y, Myers CL, Lu R, Lemischka IR, Bult CJ, Troyanskaya OG. A genomewide functional network for the laboratory mouse. Plos Computational Biology. 4: e1000165. PMID 18818725 DOI: 10.1371/journal.pcbi.1000165  0.36
2007 Fasano CA, Dimos JT, Ivanova NB, Lowry N, Lemischka IR, Temple S. shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell. 1: 87-99. PMID 18371338 DOI: 10.1016/j.stem.2007.04.001  0.36
2006 Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y, Lemischka IR. Dissecting self-renewal in stem cells with RNA interference. Nature. 442: 533-8. PMID 16767105 DOI: 10.1038/nature04915  0.36
2006 Shen Q, Wang Y, Dimos JT, Fasano CA, Phoenix TN, Lemischka IR, Ivanova NB, Stifani S, Morrisey EE, Temple S. The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nature Neuroscience. 9: 743-51. PMID 16680166 DOI: 10.1038/nn1694  0.36
2006 Schaniel C, Li F, Schafer XL, Moore T, Lemischka IR, Paddison PJ. Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells. Nature Methods. 3: 397-400. PMID 16628211 DOI: 10.1038/nmeth0506-397  0.36
2006 Pritsker M, Ford NR, Jenq HT, Lemischka IR. Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 6946-51. PMID 16621925 DOI: 10.1073/pnas.0509861103  0.36
2006 Moore KA, Lemischka IR. Stem cells and their niches. Science (New York, N.Y.). 311: 1880-5. PMID 16574858 DOI: 10.1126/science.1110542  0.36
2006 Lemischka IR, Pritsker M. Alternative splicing increases complexity of stem cell transcriptome. Cell Cycle (Georgetown, Tex.). 5: 347-51. PMID 16479168  0.36
2005 Pritsker M, Doniger TT, Kramer LC, Westcot SE, Lemischka IR. Diversification of stem cell molecular repertoire by alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 102: 14290-5. PMID 16183747 DOI: 10.1073/pnas.0502132102  0.36
2005 Lemischka IR. Stem cell biology: a view toward the future. Annals of the New York Academy of Sciences. 1044: 132-8. PMID 15958706 DOI: 10.1196/annals.1349.017  0.36
2004 Moore KA, Lemischka IR. "Tie-ing" down the hematopoietic niche. Cell. 118: 139-40. PMID 15260982 DOI: 10.1016/j.cell.2004.07.006  0.36
2003 Lemischka IR, Moore KA. Stem cells: interactive niches. Nature. 425: 778-9. PMID 14574394 DOI: 10.1038/425778a  0.36
2002 Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR. A stem cell molecular signature. Science (New York, N.Y.). 298: 601-4. PMID 12228721 DOI: 10.1126/science.1073823  0.36
2002 Hackney JA, Charbord P, Brunk BP, Stoeckert CJ, Lemischka IR, Moore KA. A molecular profile of a hematopoietic stem cell niche. Proceedings of the National Academy of Sciences of the United States of America. 99: 13061-6. PMID 12226475 DOI: 10.1073/pnas.192124499  0.36
2002 de Haan G, Bystrykh LV, Weersing E, Dontje B, Geiger H, Ivanova N, Lemischka IR, Vellenga E, Van Zant G. A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood. 100: 2056-62. PMID 12200366 DOI: 10.1182/blood-2002-03-0808  0.36
2002 Faustman DL, Pedersen RL, Kim SK, Lemischka IR, McKay RD. Cells for repair: breakout session summary. Annals of the New York Academy of Sciences. 961: 45-7. PMID 12081862  0.36
2002 Nolta JA, Thiemann FT, Arakawa-Hoyt J, Dao MA, Barsky LW, Moore KA, Lemischka IR, Crooks GM. The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors Leukemia. 16: 352-361. PMID 11896538 DOI: 10.1038/sj/leu/2402371  0.36
2001 Lewis LD, Almeida-Porada G, Du J, Lemischka IR, Moore KA, Zanjani ED, Verfaillie CM. Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system Blood. 97: 3441-3449. PMID 11369635 DOI: 10.1182/blood.V97.11.3441  0.36
2001 Lemischka IR, Jordan CT. The return of clonal marking sheds new light on human hematopoietic stem cells. Nature Immunology. 2: 11-2. PMID 11135569 DOI: 10.1038/83115  0.36
2000 Phillips RL, Ernst RE, Brunk B, Ivanova N, Mahan MA, Deanehan JK, Moore KA, Overton GC, Lemischka IR. The genetic program of hematopoietic stem cells Science. 288: 1635-1640. PMID 10834841 DOI: 10.1126/science.288.5471.1635  0.36
1999 Petrenko O, Beavis A, Klaine M, Kittappa R, Godin I, Lemischka IR. The molecular characterization of the fetal stem cell marker AA4 Immunity. 10: 691-700. PMID 10403644 DOI: 10.1016/S1074-7613(00)80068-0  0.36
1999 Punzel M, Wissink SD, Miller JS, Moore KA, Lemischka IR, Verfaillie CM. The myeloid-lymphoid initiating cell (ML-IC) assay assesses the fate of multipotent human progenitors in vitro Blood. 93: 3750-3756. PMID 10339481  0.36
1999 Punzel M, Moore KA, Lemischka IR, Verfaillie CM. The type of stromal feeder used in limiting dilution assays influences frequency and maintenance assessment of human long-term culture initiating cells Leukemia. 13: 92-97. PMID 10049066  0.36
1999 Miller JS, McCullar V, Punzel M, Lemischka IR, Moore KA. Single adult human CD34+/Lin-/CD38- progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells Blood. 93: 96-106. PMID 9864151  0.36
1998 Thiemann FT, Moore KA, Smogorzewska EM, Lemischka IR, Crooks GM. The murine stromal cell line AFT024 acts specifically on human CD34+CD38- progenitors to maintain primitive function and immunophenotype in vitro Experimental Hematology. 26: 612-619. PMID 9657136  0.36
1997 Nienhuis A, Moore MAS, Dick JE, Stamatoyannopoulos G, Lemischka IR, Torok-Storb B, Spangrude GJ, Papayannopoulou T, Flugel RM, Orlic D, Broxmeyer HE, Quesenberry PJ, Lansdorp PM, Sharkis SJ. What are the current limitations for HSC transduction? How can we overcome them?: (Discussion) Stem Cells. 15: 255-263. PMID 9368349  0.36
1997 Lansdorp PM, Lemischka IR, Dick JE, Spangrude GJ, Kaushansky K, Kanz L, Zanjani ED, Torok-Storb B, Griffin, Ogawa M, Eaves C, Quesenberry PJ. Intrinsic control of stem cell fate Stem Cells. 15: 223-227. PMID 9368346  0.36
1997 Eaves A, Moore MAS, Lansdorp PM, Spangrude GJ, Broxmeyer HE, Lemischka IR, Quesenberry PJ, Papayannopoulou T, Torok-Storb B, Hoffman R. Stem cell heterogeneity: (Discussion) Stem Cells. 15: 217-220. PMID 9368345  0.36
1997 Quesenberry PJ, Stewart MF, Peters S, Nillson S, Ramshaw H, Rao S, Tiarks C, Zhong S, Frimberger A, Reilly J, Spangrude GJ, Eaves C, Lemischka IR, Lansdorp PM, Sharkis SJ. Engraftment of hematopoietic stem cells in nonmyeloablated and myeloablated hosts Stem Cells. 15: 167-170. PMID 9368337  0.36
1997 Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K. Jaks and Stats in cytokine signaling. Stem Cells (Dayton, Ohio). 15: 105-11; discussion 1. PMID 9368330 DOI: 10.1002/stem.5530150814  0.36
1997 Lemischka IR, Sharkis SJ, Eaves C, Lansdorp PM. Microenvironmental regulation of hematopoietic stem cells Stem Cells. 15: 63-68. PMID 9368326  0.36
1997 Sharkis SJ, Collector MI, Barber JP, Vala MS, Jones RJ, Lansdorp PM, Zanjani ED, Torok-Storb B, Spangrude GJ, Buhring, Lemischka IR. Phenotypic and functional characterization of the hematopoietic stem cell Stem Cells. 15: 41-45. PMID 9368323  0.36
1997 Ogawa M, Yonemura Y, Ku H, Quesenberry PJ, Zanjani ED, Lansdorp PM, Torok-Storb B, Lemischka IR, Hoffman R, Eaves C. In vitro expansion of hematopoietic stem cells Stem Cells. 15: 7-12. PMID 9368319  0.36
1997 Moore KA, Ema H, Lemischka IR. In vitro maintenance of highly purified, transplantable hematopoietic stem cells Blood. 89: 4337-4347. PMID 9192756  0.36
1997 Harrison DE, Zhong RK, Jordan CT, Lemischka IR, Astle CM. Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term. Experimental Hematology. 25: 293-7. PMID 9131003  0.36
1997 Moore KA, Pytowski B, Witte L, Hicklin D, Lemischka IR. Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs Proceedings of the National Academy of Sciences of the United States of America. 94: 4011-4016. PMID 9108096 DOI: 10.1073/pnas.94.8.4011  0.36
1996 Dosil M, Leibman N, Lemischka IR. Cloning and characterization of fetal liver phosphatase 1, a nuclear protein tyrosine phosphatase isolated from hematopoietic stem cells Blood. 88: 4510-4525. PMID 8977243  0.36
1995 Jordan CT, Astle CM, Zawadzki J, Mackarehtschian K, Lemischka IR, Harrison DE. Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation. Experimental Hematology. 23: 1011-5. PMID 7635180  0.36
1995 Mackarehtschian K, Hardin JD, Moore KA, Boast S, Goff SP, Lemischka IR. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity. 3: 147-61. PMID 7621074 DOI: 10.1016/1074-7613(95)90167-1  0.36
1994 Tessler S, Rockwell P, Hicklin D, Cohen T, Levi BZ, Witte L, Lemischka IR, Neufeld G. Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors Journal of Biological Chemistry. 269: 12456-12461. PMID 8175651  0.36
1993 Lemischka IR. Retroviral lineage studies: some principals and applications Current Opinion in Genetics and Development. 3: 115-118. PMID 8453269 DOI: 10.1016/S0959-437X(05)80351-X  0.36
1993 Dosil M, Wang S, Lemischka IR. Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells Molecular and Cellular Biology. 13: 6572-6585. PMID 7692230  0.36
1992 Lemischka IR. The haematopoietic stem cell and its clonal progeny: Mechanisms regulating the hierarchy of primitive haematopoietic cells Cancer Surveys. 15: 3-18. PMID 1451112  0.36
1992 Lemischka IR. What we have learned from retroviral marking of hematopoietic stem cells Current Topics in Microbiology and Immunology. 177: 59-71. PMID 1353434  0.36
1992 Lemischka IR, Jordan CT, Matthews W, Mackarehtschian K. Developmental, cellular and molecular properties of hematopoietic stem cells Experimental Hematology. 20: 131-132.  0.36
1991 Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG, Lemischka IR. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proceedings of the National Academy of Sciences of the United States of America. 88: 9026-30. PMID 1717995  0.36
1991 Lemischka IR. Clonal, in vivo behavior of the totipotent hematopoietic stem cell Seminars in Immunology. 3: 349-355. PMID 1686833  0.36
1991 Matthews W, Jordan CT, Wiegand GW, Pardoll D, Lemischka IR. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell. 65: 1143-52. PMID 1648448 DOI: 10.1016/0092-8674(91)90010-V  0.36
1990 Jordan CT, McKearn JP, Lemischka IR. Cellular and developmental properties of fetal hematopoietic stem cells. Cell. 61: 953-63. PMID 1972037 DOI: 10.1016/0092-8674(90)90061-I  0.36
1990 Jordan CT, Lemischka IR. Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes & Development. 4: 220-32. PMID 1970972  0.36
1986 Lemischka IR, Raulet DH, Mulligan RC. Developmental potential and dynamic behavior of hematopoietic stem cells Cell. 45: 917-927. PMID 2871944 DOI: 10.1016/0092-8674(86)90566-0  0.36
1985 Roberts BE, Miller JS, Kimelman D, Cepko CL, Lemischka IR, Mulligan RC. Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression. Journal of Virology. 56: 404-13. PMID 4057356  0.36
1984 Williams DA, Lemischka IR, Nathan DG, Mulligan RC. Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature. 310: 476-80. PMID 6087158 DOI: 10.1038/310476a0  0.36
1983 Schwarzbauer JE, Tamkun JW, Lemischka IR, Hynes RO. Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell. 35: 421-31. PMID 6317187 DOI: 10.1016/0092-8674(83)90175-7  0.36
1981 Lemischka IR, Farmer S, Racaniello VR, Sharp PA. Nucleotide sequence and evolution of a mammalian α-Tubulin messenger RNA Journal of Molecular Biology. 151: 101-120. PMID 7328649 DOI: 10.1016/0022-2836(81)90223-0  0.36
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