Lishan Su - Publications

Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Virology Biology, Immunology, Genetics

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nunoya JI, Masuda M, Ye C, Su L. Chimeric Antigen Receptor T Cell Bearing Herpes Virus Entry Mediator Co-stimulatory Signal Domain Exhibits High Functional Potency. Molecular Therapy Oncolytics. 14: 27-37. PMID 31011630 DOI: 10.1016/j.omto.2019.03.002  0.6
2018 Lv L, Wang Q, Xu Y, Tsao LC, Nakagawa T, Guo H, Su L, Xiong Y. Vpr Targets TET2 for Degradation by CRL4 E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication. Molecular Cell. 70: 961-970.e5. PMID 29883611 DOI: 10.1016/j.molcel.2018.05.007  0.32
2017 Li G, Nunoya JI, Cheng L, Reszka-Blanco N, Tsao LC, Jeffrey J, Su L. Regulatory T Cells Contribute to HIV-1 Reservoir Persistence in CD4 T Cells Through cAMP-Dependent Mechanisms in Humanized Mice In Vivo. The Journal of Infectious Diseases. PMID 29045701 DOI: 10.1093/infdis/jix547  0.6
2017 Li G, Zhao J, Cheng L, Jiang Q, Kan S, Qin E, Tu B, Zhang X, Zhang L, Su L, Zhang Z. HIV-1 infection depletes human CD34+CD38- hematopoietic progenitor cells via pDC-dependent mechanisms. Plos Pathogens. 13: e1006505. PMID 28759657 DOI: 10.1371/journal.ppat.1006505  0.56
2016 Murphy CM, Xu Y, Li F, Nio K, Reszka-Blanco N, Li X, Wu Y, Yu Y, Xiong Y, Su L. Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Cell Reports. 16: 2846-2854. PMID 27626656 DOI: 10.1016/j.celrep.2016.08.026  0.6
2015 Whitehurst CB, Li G, Montgomery SA, Montgomery ND, Su L, Pagano JS. Knockout of Epstein-Barr Virus BPLF1 Retards B-Cell Transformation and Lymphoma Formation in Humanized Mice. Mbio. 6. PMID 26489865 DOI: 10.1128/mBio.01574-15  0.6
2015 Wang Y, McGivern DR, Cheng L, Li G, Lemon SM, Niu J, Su L, Reszka-Blanco NJ. Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. Plos One. 10: e0135232. PMID 26274905 DOI: 10.1371/journal.pone.0135232  0.6
2015 Cheng L, Li F, Bility MT, Murphy CM, Su L. Modeling hepatitis B virus infection, immunopathology and therapy in mice. Antiviral Research. PMID 26099683 DOI: 10.1016/j.antiviral.2015.06.012  0.6
2015 Reszka-Blanco NJ, Sivaraman V, Zhang L, Su L. HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms. Journal of Virology. 89: 7604-11. PMID 25972534 DOI: 10.1128/JVI.00695-15  0.6
2015 Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP. Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 589-99. PMID 25596079 DOI: 10.1016/j.nano.2014.11.010  0.6
2014 Bility MT, Curtis A, Su L. A chimeric mouse model to study immunopathogenesis of HCV infection. Methods in Molecular Biology (Clifton, N.J.). 1213: 379-88. PMID 25173399 DOI: 10.1007/978-1-4939-1453-1_31  0.6
2014 Guo H, Gao J, Taxman DJ, Ting JP, Su L. HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes. The Journal of Biological Chemistry. 289: 21716-26. PMID 24939850 DOI: 10.1074/jbc.M114.566620  0.48
2014 Bot I, Daissormont IT, Zernecke A, van Puijvelde GH, Kramp B, de Jager SC, Sluimer JC, Manca M, Hérias V, Westra MM, Bot M, van Santbrink PJ, van Berkel TJ, Su L, Skjelland M, et al. CXCR4 blockade induces atherosclerosis by affecting neutrophil function. Journal of Molecular and Cellular Cardiology. 74: 44-52. PMID 24816217 DOI: 10.1016/j.yjmcc.2014.04.021  0.6
2014 Nunoya J, Washburn ML, Kovalev GI, Su L. Regulatory T cells prevent liver fibrosis during HIV type 1 infection in a humanized mouse model. The Journal of Infectious Diseases. 209: 1039-44. PMID 24133182 DOI: 10.1093/infdis/jit548  0.6
2013 Wang Y, Misumi I, Gu AD, Curtis TA, Su L, Whitmire JK, Wan YY. GATA-3 controls the maintenance and proliferation of T cells downstream of TCR and cytokine signaling. Nature Immunology. 14: 714-22. PMID 23708251 DOI: 10.1038/ni.2623  0.6
2012 Bility MT, Zhang L, Washburn ML, Curtis TA, Kovalev GI, Su L. Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis. Nature Protocols. 7: 1608-17. PMID 22899330 DOI: 10.1038/nprot.2012.083  0.6
2012 Su L. Studying human immunology and immunopathology in humanized mice transplanted with human lymphoid tissues and immune cells. Cellular & Molecular Immunology. 9: 191-2. PMID 22565218 DOI: 10.1038/cmi.2012.4  0.6
2011 Holmes D, Gao J, Su L. Foxp3 inhibits HDAC1 activity to modulate gene expression in human T cells. Virology. 421: 12-8. PMID 21974802 DOI: 10.1016/j.virol.2011.09.002  0.48
2011 Hench VK, Su L. Regulation of IL-2 gene expression by Siva and FOXP3 in human T cells. Bmc Immunology. 12: 54. PMID 21955384 DOI: 10.1186/1471-2172-12-54  0.6
2011 Sivaraman V, Zhang L, Su L. Type I interferon contributes to CD4+ T cell depletion induced by infection with HIV-1 in the human thymus. Journal of Virology. 85: 9243-6. PMID 21697497 DOI: 10.1128/JVI.00457-11  0.6
2011 Mackey-Cushman SL, Gao J, Holmes DA, Nunoya JI, Wang R, Unutmaz D, Su L. FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity. Genes and Immunity. 12: 559-67. PMID 21654845 DOI: 10.1038/gene.2011.31  0.6
2011 Zhang L, Jiang Q, Li G, Jeffrey J, Kovalev GI, Su L. Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2⁻/⁻γ C⁻/⁻ mice in vivo. Blood. 117: 6184-92. PMID 21505190 DOI: 10.1182/blood-2011-01-331173  0.6
2011 Washburn ML, Bility MT, Zhang L, Kovalev GI, Buntzman A, Frelinger JA, Barry W, Ploss A, Rice CM, Su L. A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology. 140: 1334-44. PMID 21237170 DOI: 10.1053/j.gastro.2011.01.001  0.6
2011 West JA, Gregory SM, Sivaraman V, Su L, Damania B. Activation of plasmacytoid dendritic cells by Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 85: 895-904. PMID 20980519 DOI: 10.1128/JVI.01007-10  0.6
2010 Zhang LG, Meissner E, Chen JZ, Su LS. Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis Science China Life Sciences. 53: 195-203. PMID 20596827 DOI: 10.1007/s11427-010-0059-7  0.6
2010 Johnson SM, Torrice CD, Bell JF, Monahan KB, Jiang Q, Wang Y, Ramsey MR, Jin J, Wong KK, Su L, Zhou D, Sharpless NE. Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. The Journal of Clinical Investigation. 120: 2528-36. PMID 20577054 DOI: 10.1172/JCI41402  0.6
2010 Washburn ML, Kovalev GI, Koroleva E, Fu YX, Su L. LIGHT induces distinct signals to clear an AAV-expressed persistent antigen in the mouse liver and to induce liver inflammation. Plos One. 5: e10585. PMID 20498840 DOI: 10.1371/journal.pone.0010585  0.6
2010 Ince WL, Zhang L, Jiang Q, Arrildt K, Su L, Swanstrom R. Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model. Journal of Virology. 84: 2740-52. PMID 20042504 DOI: 10.1128/JVI.02180-09  0.6
2009 Sivaraman V, Zhang L, Meissner EG, Jeffrey JL, Su L. The heptad repeat 2 domain is a major determinant for enhanced human immunodeficiency virus type 1 (HIV-1) fusion and pathogenicity of a highly pathogenic HIV-1 Env. Journal of Virology. 83: 11715-25. PMID 19726524 DOI: 10.1128/JVI.00649-09  0.6
2009 Choudhary SK, Rezk NL, Ince WL, Cheema M, Zhang L, Su L, Swanstrom R, Kashuba AD, Margolis DM. Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{gamma}c-/- mouse. Journal of Virology. 83: 8254-8. PMID 19494021 DOI: 10.1128/JVI.00580-09  0.6
2008 Holmes D, Jiang Q, Zhang L, Su L. Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis. Immunologic Research. 41: 248-66. PMID 18726715 DOI: 10.1007/s12026-008-8037-x  0.56
2008 Jiang Q, Zhang L, Wang R, Jeffrey J, Washburn ML, Brouwer D, Barbour S, Kovalev GI, Unutmaz D, Su L. FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood. 112: 2858-68. PMID 18544681 DOI: 10.1182/blood-2008-03-145946  0.6
2008 Lu X, Kovalev GI, Chang H, Kallin E, Knudsen G, Xia L, Mishra N, Ruiz P, Li E, Su L, Zhang Y. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. The Journal of Biological Chemistry. 283: 13825-33. PMID 18353770 DOI: 10.1074/jbc.M801275200  0.6
2007 Laakso MM, Lee FH, Haggarty B, Agrawal C, Nolan KM, Biscone M, Romano J, Jordan AP, Leslie GJ, Meissner EG, Su L, Hoxie JA, Doms RW. V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. Plos Pathogens. 3: e117. PMID 17722977 DOI: 10.1371/journal.ppat.0030117  0.6
2007 Jiang Q, Coffield VM, Kondo M, Su L. TSLP is involved in expansion of early thymocyte progenitors. Bmc Immunology. 8: 11. PMID 17640367 DOI: 10.1186/1471-2172-8-11  0.6
2007 Helms WS, Jeffrey JL, Holmes DA, Townsend MB, Clipstone NA, Su L. Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells. Journal of Leukocyte Biology. 82: 361-9. PMID 17502338 DOI: 10.1189/jlb.0206120  0.6
2007 Zhang L, Kovalev GI, Su L. HIV-1 infection and pathogenesis in a novel humanized mouse model. Blood. 109: 2978-81. PMID 17132723 DOI: 10.1182/blood-2006-07-033159  0.6
2007 Su L. PD-1+ T cells: Exhausted and premature? Blood. 109: 4593-4594. DOI: 10.1182/blood-2007-03-079434  0.6
2006 Loomis RJ, Holmes DA, Elms A, Solski PA, Der CJ, Su L. Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis. Traffic (Copenhagen, Denmark). 7: 1643-53. PMID 17118119 DOI: 10.1111/j.1600-0854.2006.00503.x  0.6
2006 Meissner EG, Zhang L, Jiang S, Su L. Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus. Journal of Virology. 80: 11019-30. PMID 16956934 DOI: 10.1128/JVI.01382-06  0.6
2006 Okada Y, Jiang Q, Lemieux M, Jeannotte L, Su L, Zhang Y. Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. Nature Cell Biology. 8: 1017-24. PMID 16921363 DOI: 10.1038/ncb1464  0.56
2006 Jiang Q, Su H, Knudsen G, Helms W, Su L. Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP. Bmc Immunology. 7: 6. PMID 16579866 DOI: 10.1186/1471-2172-7-6  0.56
2005 Chang X, Gao JX, Jiang Q, Wen J, Seifers N, Su L, Godfrey VL, Zuo T, Zheng P, Liu Y. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. The Journal of Experimental Medicine. 202: 1141-51. PMID 16230479 DOI: 10.1084/jem.20050157  0.56
2005 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/jbc.M502820200  0.6
2005 Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, Taylor PA, McKinnon KP, Su L, Blazar BR, Serody JS. Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease. Blood. 106: 3300-7. PMID 16002422 DOI: 10.1182/blood-2005-04-1632  0.6
2005 Meissner EG, Coffield VM, Su L. Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry. Virology. 336: 184-97. PMID 15892960 DOI: 10.1016/j.virol.2005.03.032  0.6
2005 Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y. hDOT1L links histone methylation to leukemogenesis. Cell. 121: 167-78. PMID 15851025 DOI: 10.1016/j.cell.2005.05.021  0.6
2004 Coffield VM, Helms WS, Jiang Q, Su L. Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors. The Journal of Experimental Medicine. 200: 1315-24. PMID 15534370 DOI: 10.1084/jem.20040944  0.6
2004 Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Ink4a/Arf expression is a biomarker of aging. The Journal of Clinical Investigation. 114: 1299-307. PMID 15520862 DOI: 10.1172/JCI22475  0.6
2004 Meissner EG, Duus KM, Gao F, Yu XF, Su L. Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope. Virology. 328: 74-88. PMID 15380360 DOI: 10.1016/j.virol.2004.07.019  0.6
2003 Coffield VM, Su L. Receptor-ligand genetics: Inactivation of receptors with a modified viral protein. Discovery Medicine. 3: 30-2. PMID 20705033  0.88
2003 Meissner EG, Duus KM, Loomis R, D'Agostin R, Su L. HIV-1 replication and pathogenesis in the human thymus. Current Hiv Research. 1: 275-85. PMID 15046252  0.6
2003 Gebuhr TC, Kovalev GI, Bultman S, Godfrey V, Su L, Magnuson T. The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. The Journal of Experimental Medicine. 198: 1937-49. PMID 14676303 DOI: 10.1084/jem.20030714  0.6
2003 Coffield VM, Jiang Q, Su L. A genetic approach to inactivating chemokine receptors using a modified viral protein. Nature Biotechnology. 21: 1321-7. PMID 14555957 DOI: 10.1038/nbt889  0.88
2002 Solski PA, Helms W, Keely PJ, Su L, Der CJ. RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 363-73. PMID 12193475  0.6
2001 Kovalev GI, Franklin DS, Coffield VM, Xiong Y, Su L. An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 167: 3285-92. PMID 11544316  0.6
1997 Su L. HIV-1 pathogenesis and therapeutic intervention in the SCID-hu Thy/Liv mouse: A model for primary HIV-1 infection in the human thymus Reviews in Medical Virology. 7: 157-166. DOI: 10.1002/(SICI)1099-1654(199709)7:3<157::AID-RMV197>3.0.CO;2-R  0.6
1995 Bonyhadi ML, Su L, Auten J, McCune JM, Kaneshima H. Development of a human thymic organ culture model for the study of HIV pathogenesis Aids Research and Human Retroviruses. 11: 1073-1080. PMID 8554904  0.6
1994 Kaneshima H, Su L, Bonyhadi ML, Connor RI, Ho DD, Mccune JM. Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse Journal of Virology. 68: 8188-8192. PMID 7966610  0.6
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