Jeffrey L. Benovic - Publications

Affiliations: 
Biochemistry and Molecular Biology Thomas Jefferson University 
Area:
Molecular Biology, Biochemistry

218 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lagman J, Sayegh P, Lee CS, Sulon SM, Jacinto AZ, Sok V, Peng N, Alp D, Benovic JL, So CH. G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel. Molecular and Cellular Biochemistry. PMID 31363957 DOI: 10.1007/s11010-019-03594-9  0.4
2016 Carr R, Schilling J, Song J, Carter RL, Du Y, Yoo SM, Traynham CJ, Koch WJ, Cheung JY, Tilley DG, Benovic JL. β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27354517 DOI: 10.1073/pnas.1606267113  0.4
2015 Carr R, Koziol-White C, Zhang J, Lam H, Ahn SS, Tall GG, Panettieri RA, Benovic JL. Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Molecular Pharmacology. PMID 26464325 DOI: 10.1124/mol.115.100339  0.4
2015 Benovic JL. Structural biology: Arresting developments in receptor signalling. Nature. 523: 538-9. PMID 26200346 DOI: 10.1038/nature14637  0.4
2015 Komolov KE, Bhardwaj A, Benovic JL. Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases. The Journal of Biological Chemistry. 290: 20629-47. PMID 26032409 DOI: 10.1074/jbc.M115.647297  0.4
2015 Augello MA, Berman-Booty LD, Carr R, Yoshida A, Dean JL, Schiewer MJ, Feng FY, Tomlins SA, Gao E, Koch WJ, Benovic JL, Diehl JA, Knudsen KE. Consequence of the tumor-associated conversion to cyclin D1b. Embo Molecular Medicine. 7: 628-47. PMID 25787974 DOI: 10.15252/emmm.201404242  0.4
2015 Benovic JL, Armstrong RN. New frontiers in kinases. Biochemistry. 54: 1. PMID 25517407 DOI: 10.1021/bi501533e  0.4
2014 Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL. Development and characterization of pepducins as Gs-biased allosteric agonists. The Journal of Biological Chemistry. 289: 35668-84. PMID 25395624 DOI: 10.1074/jbc.M114.618819  0.4
2014 Kang DS, Tian X, Benovic JL. Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking. Current Opinion in Cell Biology. 27: 63-71. PMID 24680432 DOI: 10.1016/j.ceb.2013.11.005  0.4
2014 Benovic JL, Armstrong RN. Call for papers! A special thematic compilation/special issue crossover with ACS Chemical Biology, ACS Medicinal Chemistry Letters, and the Journal of Medicinal Chemistry focused on new frontiers in kinases. Biochemistry. 53: 1723. PMID 24660987 DOI: 10.1021/bi500258s  0.4
2014 Benovic JL, von Zastrow M. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors. Current Opinion in Cell Biology. 27: v-vi. PMID 24529749 DOI: 10.1016/j.ceb.2014.01.009  0.4
2014 Tian X, Kang DS, Benovic JL. β-arrestins and G protein-coupled receptor trafficking. Handbook of Experimental Pharmacology. 219: 173-86. PMID 24292830 DOI: 10.1007/978-3-642-41199-1_9  0.4
2013 Quoyer J, Janz JM, Luo J, Ren Y, Armando S, Lukashova V, Benovic JL, Carlson KE, Hunt SW, Bouvier M. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein. Proceedings of the National Academy of Sciences of the United States of America. 110: E5088-97. PMID 24309376 DOI: 10.1073/pnas.1312515110  0.4
2013 So CH, Michal A, Komolov KE, Luo J, Benovic JL. G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation. Molecular Biology of the Cell. 24: 2795-806. PMID 23904266 DOI: 10.1091/mbc.E13-01-0013  0.4
2013 Kang DS, Tian X, Benovic JL. β-Arrestins and G protein-coupled receptor trafficking. Methods in Enzymology. 521: 91-108. PMID 23351735 DOI: 10.1016/B978-0-12-391862-8.00005-3  0.4
2013 Chen YJ, Oldfield S, Butcher AJ, Tobin AB, Saxena K, Gurevich VV, Benovic JL, Henderson G, Kelly E. Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor. Journal of Neurochemistry. 124: 189-99. PMID 23106126 DOI: 10.1111/jnc.12071  0.4
2012 Benovic JL. G-protein-coupled receptors signal victory. Cell. 151: 1148-50. PMID 23201142 DOI: 10.1016/j.cell.2012.11.015  0.4
2012 So CH, Michal AM, Mashayekhi R, Benovic JL. G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition. The Journal of Biological Chemistry. 287: 17088-99. PMID 22467873 DOI: 10.1074/jbc.M112.353854  0.4
2012 Wood JF, Wang J, Benovic JL, Ferkey DM. Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo. The Journal of Biological Chemistry. 287: 12634-44. PMID 22375004 DOI: 10.1074/jbc.M111.336818  0.4
2012 Michal AM, So CH, Beeharry N, Shankar H, Mashayekhi R, Yen TJ, Benovic JL. G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression. The Journal of Biological Chemistry. 287: 6928-40. PMID 22223642 DOI: 10.1074/jbc.M111.298034  0.4
2012 Woerner BM, Luo J, Brown KR, Jackson E, Dahiya SM, Mischel P, Benovic JL, Piwnica-Worms D, Rubin JB. Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth. Molecular Cancer Research : McR. 10: 156-66. PMID 22086906 DOI: 10.1158/1541-7786.MCR-11-0411  0.4
2011 Barker BL, Benovic JL. G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. Biochemistry. 50: 6933-41. PMID 21728385 DOI: 10.1021/bi2005202  0.4
2011 Michal AM, Peck AR, Tran TH, Liu C, Rimm DL, Rui H, Benovic JL. Differential expression of arrestins is a predictor of breast cancer progression and survival. Breast Cancer Research and Treatment. 130: 791-807. PMID 21318602 DOI: 10.1007/s10549-011-1374-9  0.4
2010 Sosa MS, Lopez-Haber C, Yang C, Wang H, Lemmon MA, Busillo JM, Luo J, Benovic JL, Klein-Szanto A, Yagi H, Gutkind JS, Parsons RE, Kazanietz MG. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. Molecular Cell. 40: 877-92. PMID 21172654 DOI: 10.1016/j.molcel.2010.11.029  0.4
2010 Palmitessa A, Benovic JL. Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity. The Journal of Biological Chemistry. 285: 15187-200. PMID 20207731 DOI: 10.1074/jbc.M110.104612  0.4
2010 Shankar H, Michal A, Kern RC, Kang DS, Gurevich VV, Benovic JL. Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function. The Journal of Biological Chemistry. 285: 8316-29. PMID 20056609 DOI: 10.1074/jbc.M109.062521  0.4
2010 Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. The Journal of Biological Chemistry. 285: 7805-17. PMID 20048153 DOI: 10.1074/jbc.M109.091173  0.4
2010 Patial S, Luo J, Porter KJ, Benovic JL, Parameswaran N. G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα. The Biochemical Journal. 425: 169-78. PMID 19796012 DOI: 10.1042/BJ20090908  0.4
2009 Pao CS, Barker BL, Benovic JL. Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry. 48: 7325-33. PMID 19715378 DOI: 10.1021/bi900408g  0.4
2009 Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. The Journal of Biological Chemistry. 284: 29860-72. PMID 19710023 DOI: 10.1074/jbc.M109.023366  0.4
2009 Kern RC, Kang DS, Benovic JL. Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2. Biochemistry. 48: 7190-200. PMID 19555118 DOI: 10.1021/bi900369c  0.4
2009 Yang M, He RL, Benovic JL, Ye RD. beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation. The Biochemical Journal. 417: 287-96. PMID 18729826 DOI: 10.1042/BJ20081561  0.4
2008 Luo J, Busillo JM, Benovic JL. M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms. Molecular Pharmacology. 74: 338-47. PMID 18388243 DOI: 10.1124/mol.107.044750  0.4
2008 Ahmed MR, Gurevich VV, Dalby KN, Benovic JL, Gurevich EV. Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation. The Journal of Pharmacology and Experimental Therapeutics. 325: 276-83. PMID 18178904 DOI: 10.1124/jpet.107.131987  0.4
2008 Penn RB, Benovic JL. Regulation of heterotrimeric G protein signaling in airway smooth muscle. Proceedings of the American Thoracic Society. 5: 47-57. PMID 18094084 DOI: 10.1513/pats.200705-054VS  0.4
2008 Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment. Journal of Neurochemistry. 104: 1622-36. PMID 17996024 DOI: 10.1111/j.1471-4159.2007.05104.x  0.4
2008 Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV. Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia Neurobiology of Aging. 29: 379-396. PMID 17125886 DOI: 10.1016/j.neurobiolaging.2006.10.012  0.4
2007 Bhandari D, Trejo J, Benovic JL, Marchese A. Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. The Journal of Biological Chemistry. 282: 36971-9. PMID 17947233 DOI: 10.1074/jbc.M705085200  0.4
2007 Jiang X, Benovic JL, Wedegaertner PB. Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A. Molecular Biology of the Cell. 18: 2960-9. PMID 17538017 DOI: 10.1091/mbc.E07-01-0013  0.4
2007 Busillo JM, Benovic JL. Regulation of CXCR4 signaling. Biochimica Et Biophysica Acta. 1768: 952-63. PMID 17169327 DOI: 10.1016/j.bbamem.2006.11.002  0.4
2007 Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking by GRKs and arrestins. Annual Review of Physiology. 69: 451-82. PMID 17037978 DOI: 10.1146/annurev.physiol.69.022405.154712  0.4
2006 Parameswaran N, Pao CS, Leonhard KS, Kang DS, Kratz M, Ley SC, Benovic JL. Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. The Journal of Biological Chemistry. 281: 34159-70. PMID 16980301 DOI: 10.1074/jbc.M605376200  0.4
2006 Mundell SJ, Luo J, Benovic JL, Conley PB, Poole AW. Distinct clathrin-coated pits sort different G protein-coupled receptor cargo. Traffic (Copenhagen, Denmark). 7: 1420-31. PMID 16899088 DOI: 10.1111/j.1600-0854.2006.00469.x  0.4
2006 Lodowski DT, Tesmer VM, Benovic JL, Tesmer JJ. The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs. The Journal of Biological Chemistry. 281: 16785-93. PMID 16613860 DOI: 10.1074/jbc.M601327200  0.4
2006 Milano SK, Kim YM, Stefano FP, Benovic JL, Brenner C. Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding. The Journal of Biological Chemistry. 281: 9812-23. PMID 16439357 DOI: 10.1074/jbc.M512703200  0.4
2005 Rutherford C, Ord-Shrimpton FU, Sands WA, Pediani JD, Benovic JL, McGrath JC, Palmer TM. Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3. Cellular Signalling. 17: 997-1009. PMID 15894172 DOI: 10.1016/j.cellsig.2004.11.018  0.4
2005 Palmitessa A, Hess HA, Bany IA, Kim YM, Koelle MR, Benovic JL. Caenorhabditus elegans arrestin regulates neural G protein signaling and olfactory adaptation and recovery. The Journal of Biological Chemistry. 280: 24649-62. PMID 15878875 DOI: 10.1074/jbc.M502637200  0.4
2005 Hardy AR, Conley PB, Luo J, Benovic JL, Poole AW, Mundell SJ. P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms. Blood. 105: 3552-60. PMID 15665114 DOI: 10.1182/blood-2004-07-2893  0.4
2005 Pao CS, Benovic JL. Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 11052-8. PMID 15653687 DOI: 10.1074/jbc.M412996200  0.4
2005 Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. The Journal of Biological Chemistry. 280: 8722-32. PMID 15590629 DOI: 10.1074/jbc.M413014200  0.4
2005 Iwata K, Luo J, Penn RB, Benovic JL. Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 2197-204. PMID 15542600 DOI: 10.1074/jbc.M408834200  0.4
2004 Gurevich EV, Benovic JL, Gurevich VV. Arrestin2 expression selectively increases during neural differentiation. Journal of Neurochemistry. 91: 1404-16. PMID 15584917 DOI: 10.1111/j.1471-4159.2004.02830.x  0.4
2004 Benovic JL, Marchese A. A new key in breast cancer metastasis. Cancer Cell. 6: 429-30. PMID 15542424 DOI: 10.1016/j.ccr.2004.10.017  0.4
2004 Day PW, Wedegaertner PB, Benovic JL. Analysis of G-protein-coupled receptor kinase RGS homology domains. Methods in Enzymology. 390: 295-310. PMID 15488185 DOI: 10.1016/S0076-6879(04)90019-5  0.4
2004 Day PW, Tesmer JJ, Sterne-Marr R, Freeman LC, Benovic JL, Wedegaertner PB. Characterization of the GRK2 binding site of Galphaq. The Journal of Biological Chemistry. 279: 53643-52. PMID 15471870 DOI: 10.1074/jbc.M401438200  0.4
2004 Marchese A, Benovic JL. Ubiquitination of G-protein-coupled receptors. Methods in Molecular Biology (Clifton, N.J.). 259: 299-305. PMID 15250500 DOI: 10.1385/1-59259-754-8:299  0.4
2004 Thiyagarajan MM, Stracquatanio RP, Pronin AN, Evanko DS, Benovic JL, Wedegaertner PB. A predicted amphipathic helix mediates plasma membrane localization of GRK5. The Journal of Biological Chemistry. 279: 17989-95. PMID 14976207 DOI: 10.1074/jbc.M310738200  0.4
2004 Vishnivetskiy SA, Hosey MM, Benovic JL, Gurevich VV. Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins. The Journal of Biological Chemistry. 279: 1262-8. PMID 14530255 DOI: 10.1074/jbc.M308834200  0.4
2003 Gutierrez-Ford C, Levay K, Gomes AV, Perera EM, Som T, Kim YM, Benovic JL, Berkovitz GD, Slepak VZ. Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin. Biochemistry. 42: 14553-65. PMID 14661968 DOI: 10.1021/bi034870f  0.4
2003 Luo J, Benovic JL. G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. The Journal of Biological Chemistry. 278: 50908-14. PMID 14557268 DOI: 10.1074/jbc.M307637200  0.4
2003 Noble B, Kallal LA, Pausch MH, Benovic JL. Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation. The Journal of Biological Chemistry. 278: 47466-76. PMID 14507916 DOI: 10.1074/jbc.M308257200  0.4
2003 Day PW, Carman CV, Sterne-Marr R, Benovic JL, Wedegaertner PB. Differential interaction of GRK2 with members of the G alpha q family. Biochemistry. 42: 9176-84. PMID 12885252 DOI: 10.1021/bi034442+  0.4
2003 Marchese A, Chen C, Kim YM, Benovic JL. The ins and outs of G protein-coupled receptor trafficking. Trends in Biochemical Sciences. 28: 369-76. PMID 12878004 DOI: 10.1016/S0968-0004(03)00134-8  0.4
2003 Sterne-Marr R, Tesmer JJ, Day PW, Stracquatanio RP, Cilente JA, O'Connor KE, Pronin AN, Benovic JL, Wedegaertner PB. G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits. The Journal of Biological Chemistry. 278: 6050-8. PMID 12427730 DOI: 10.1074/jbc.M208787200  0.4
2002 Benovic JL. Novel beta2-adrenergic receptor signaling pathways. The Journal of Allergy and Clinical Immunology. 110: S229-35. PMID 12464929 DOI: 10.1067/mai.2002.129370  0.4
2002 Pao CS, Benovic JL. Phosphorylation-independent desensitization of G protein-coupled receptors? Science's Stke : Signal Transduction Knowledge Environment. 2002: pe42. PMID 12372852 DOI: 10.1126/stke.2002.153.pe42  0.4
2002 DeGraff JL, Gurevich VV, Benovic JL. The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction. The Journal of Biological Chemistry. 277: 43247-52. PMID 12205092 DOI: 10.1074/jbc.M207495200  0.4
2002 Kim YM, Benovic JL. Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking. The Journal of Biological Chemistry. 277: 30760-8. PMID 12070169 DOI: 10.1074/jbc.M204528200  0.4
2002 Kim YM, Barak LS, Caron MG, Benovic JL. Regulation of arrestin-3 phosphorylation by casein kinase II. The Journal of Biological Chemistry. 277: 16837-46. PMID 11877451 DOI: 10.1074/jbc.M201379200  0.4
2002 Milano SK, Pace HC, Kim YM, Brenner C, Benovic JL. Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis. Biochemistry. 41: 3321-8. PMID 11876640 DOI: 10.1021/bi015905j  0.4
2002 Gurevich EV, Benovic JL, Gurevich VV. Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development Neuroscience. 109: 421-436. PMID 11823056 DOI: 10.1016/S0306-4522(01)00511-5  0.4
2002 Watterson KR, Johnston E, Chalmers C, Pronin A, Cook SJ, Benovic JL, Palmer TM. Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 277: 5767-77. PMID 11741892 DOI: 10.1074/jbc.M110647200  0.4
2002 Mundell SJ, Orsini MJ, Benovic JL. Characterization of arrestin expression and function. Methods in Enzymology. 343: 600-11. PMID 11665594 DOI: 10.1016/S0076-6879(02)43160-6  0.4
2002 Pronin AN, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor kinases. Methods in Enzymology. 343: 547-59. PMID 11665591 DOI: 10.1016/S0076-6879(02)43157-6  0.4
2002 Kallal L, Benovic JL. Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking. Methods in Enzymology. 343: 492-506. PMID 11665588 DOI: 10.1016/S0076-6879(02)43154-0  0.4
2001 Marchese A, Benovic JL. Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. The Journal of Biological Chemistry. 276: 45509-12. PMID 11641392 DOI: 10.1074/jbc.C100527200  0.4
2001 Matharu AL, Mundell SJ, Benovic JL, Kelly E. Rapid Agonist-induced Desensitization and Internalization of the A 2B Adenosine Receptor is Mediated by a Serine Residue Close to the COOH Terminus Journal of Biological Chemistry. 276: 30199-30207. PMID 11333255 DOI: 10.1074/jbc.M010650200  0.4
2001 Mundell SJ, Olah ME, Panettieri J, Benovic JL, Penn RB. Regulation of g protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine American Journal of Respiratory Cell and Molecular Biology. 24: 155-163. PMID 11159049  0.4
2001 Parent JL, Labrecque P, Driss Rochdi M, Benovic JL. Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization. The Journal of Biological Chemistry. 276: 7079-85. PMID 11112783 DOI: 10.1074/jbc.M009375200  0.4
2000 Mundell SJ, Matharu AL, Kelly E, Benovic JL. Arrestin isoforms dictate differential kinetics of A2(B) adenosine receptor trafficking Biochemistry. 39: 12828-12836. PMID 11041847 DOI: 10.1021/bi0010928  0.4
2000 Li JG, Benovic JL, Liu-Chen LY. Mechanisms of agonist-induced down-regulation of the human kappa-opioid receptor: internalization is required for down-regulation. Molecular Pharmacology. 58: 795-801. PMID 10999950  0.4
2000 Pronin AN, Morris AJ, Surguchov A, Benovic JL. Synucleins are a novel class of substrates for G protein-coupled receptor kinases Journal of Biological Chemistry. 275: 26515-26522. PMID 10852916 DOI: 10.1074/jbc.M003542200  0.4
2000 Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH. Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors Journal of Cell Science. 113: 2463-2470. PMID 10852825  0.4
2000 Kallal L, Benovic JL. Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking Trends in Pharmacological Sciences. 21: 175-180. PMID 10785651 DOI: 10.1016/S0165-6147(00)01477-2  0.4
2000 Mundell SJ, Benovic JL. Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells Journal of Biological Chemistry. 275: 12900-12908. PMID 10777589 DOI: 10.1074/jbc.275.17.12900  0.4
2000 Gurevich VV, Benovic JL. Arrestin: Mutagenesis, expression, purification, and functional characterization Methods in Enzymology. 315: 422-437. PMID 10736718  0.4
1999 Willets JM, Parent JL, Benovic JL, Kelly E. Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression. Journal of Neurochemistry. 73: 1781-9. PMID 10537035 DOI: 10.1046/j.1471-4159.1999.0731781.x  0.4
1999 Orsini MJ, Parent JL, Mundell SJ, Marchese A, Benovic JL. Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization. The Journal of Biological Chemistry. 274: 31076-86. PMID 10521508 DOI: 10.1074/jbc.274.43.31076  0.4
1999 Mundell SJ, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels Biochemistry. 38: 8723-8732. PMID 10393547 DOI: 10.1021/bi990361v  0.4
1999 Lazari MDFM, Liu X, Nakamura K, Benovic JL, Ascoli M. Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor Molecular Endocrinology. 13: 866-878. PMID 10379886  0.4
1999 Wang YX, Dhulipala PDK, Li L, Benovic JL, Kotlikoff MI. Coupling of M2 muscarinic receptors to membrane ion channels via phosphoinositide 3-kinase γ and atypical protein kinase C Journal of Biological Chemistry. 274: 13859-13864. PMID 10318793 DOI: 10.1074/jbc.274.20.13859  0.4
1999 DeGraff JL, Gagnon AW, Benovic JL, Orsini MJ. Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes. The Journal of Biological Chemistry. 274: 11253-9. PMID 10196213 DOI: 10.1074/jbc.274.16.11253  0.4
1999 Parent JL, Labrecque P, Orsini MJ, Benovic JL. Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization. The Journal of Biological Chemistry. 274: 8941-8. PMID 10085139 DOI: 10.1074/jbc.274.13.8941  0.4
1999 Carman CV, Lisanti MP, Benovic JL. Regulation of G protein-coupled receptor kinases by caveolin Journal of Biological Chemistry. 274: 8858-8864. PMID 10085129 DOI: 10.1074/jbc.274.13.8858  0.4
1999 Gaidarov I, Krupnick JG, Falck JR, Benovic JL, Keen JH. Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding Embo Journal. 18: 871-881. PMID 10022830 DOI: 10.1093/emboj/18.4.871  0.4
1998 Orsini MJ, Benovic JL. Characterization of dominant negative arrestins that inhibit β2- adrenergic receptor internalization by distinct mechanisms Journal of Biological Chemistry. 273: 34616-34622. PMID 9852134 DOI: 10.1074/jbc.273.51.34616  0.4
1998 Pronin AN, Carman CV, Benovic JL. Structure-function analysis of G protein-coupled receptor kinase-5: Role of the carboxyl terminus in kinase regulation Journal of Biological Chemistry. 273: 31510-31518. PMID 9813065 DOI: 10.1074/jbc.273.47.31510  0.4
1998 Mundell SJ, Luty JS, Willets J, Benovic JL, Kelly E. Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A(2A) adenosine receptors to agonist-induced desensitization British Journal of Pharmacology. 125: 347-356. PMID 9786508 DOI: 10.1038/sj.bjp.0702081  0.4
1998 Levay K, Satpaev DK, Pronin AN, Benovic JL, Slepak VZ. Localization of the sites for Ca2+-binding proteins on G protein- coupled receptor kinases Biochemistry. 37: 13650-13659. PMID 9753452 DOI: 10.1021/bi980998z  0.4
1998 Nakamura K, Krupnick JG, Benovic JL, Ascoli M. Signaling and phosphorylation-impaired mutants of the rat follitropin receptor reveal an activation- and phosphorylation-independent but arrestin- dependent pathway for internalization Journal of Biological Chemistry. 273: 24346-24354. PMID 9733722 DOI: 10.1074/jbc.273.38.24346  0.4
1998 Penn RB, Panettieri RA, Benovic JL. Mechanisms of acute desensitization of the β2AR-adenylyl cyclase pathway in human airway smooth muscle American Journal of Respiratory Cell and Molecular Biology. 19: 338-348. PMID 9698608  0.4
1998 Carman CV, Benovic JL. G-protein-coupled receptors: Turn-ons and turn-offs Current Opinion in Neurobiology. 8: 335-344. PMID 9687355 DOI: 10.1016/S0959-4388(98)80058-5  0.4
1998 Carman CV, Som T, Kim CM, Benovic JL. Binding and phosphorylation of tubulin by G protein-coupled receptor kinases Journal of Biological Chemistry. 273: 20308-20316. PMID 9685381 DOI: 10.1074/jbc.273.32.20308  0.4
1998 Krupnick JG, Benovic JL. The role of receptor kinases and arrestins in G protein-coupled receptor regulation Annual Review of Pharmacology and Toxicology. 38: 289-319. PMID 9597157  0.4
1998 Lee KB, Pals-Rylaarsdam R, Benovic JL, Hosey MM. Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors Journal of Biological Chemistry. 273: 12967-12972. PMID 9582330 DOI: 10.1074/jbc.273.21.12967  0.4
1998 Wu G, Benovic JL, Hildebrandt JD, Lanier SM. Receptor docking sites for G-protein βγ subunits. Implications for signal regulation Journal of Biological Chemistry. 273: 7197-7200. PMID 9516410 DOI: 10.1074/jbc.273.13.7197  0.4
1998 Gagnon AW, Kallal L, Benovic JL. Role of clathrin-mediated endocytosis in agonist-induced down-regulation of the β2-adrenergic receptor Journal of Biological Chemistry. 273: 6976-6981. PMID 9507004 DOI: 10.1074/jbc.273.12.6976  0.4
1998 Kallal L, Gagnon AW, Penn RB, Benovic JL. Visualization of agonist-induced sequestration and down-regulation of a green fluorescent protein-tagged β2-adrenergic receptor Journal of Biological Chemistry. 273: 322-328. PMID 9417083 DOI: 10.1074/jbc.273.1.322  0.4
1998 Wu G, Benovic JL, Hildebrandt JD, Lanier SM. Receptor docking sites for G-protein:βγ subunits: Implications for signal regulation Faseb Journal. 12.  0.4
1997 Krupnick JG, Santini F, Gagnon AW, Keen JH, Benovic JL. Modulation of the arrestin-clathrin interaction in cells: Characterization of β-arrestin dominant-negative mutants Journal of Biological Chemistry. 272: 32507-32512. PMID 9405462 DOI: 10.1074/jbc.272.51.32507  0.4
1997 Fukayama S, Kong G, Benovic JL, Meurer E, Tashjian AH. β-adrenergic receptor kinase-1 acutely regulates PTH/PTHrP receptor signalling in human osteoblastlike cells Cellular Signalling. 9: 469-474. PMID 9376230 DOI: 10.1016/S0898-6568(97)00044-2  0.4
1997 Gurevich VV, Pals-Rylaarsdam R, Benovic JL, Hosey MM, Onorato JJ. Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity Journal of Biological Chemistry. 272: 28849-28852. PMID 9360951 DOI: 10.1074/jbc.272.46.28849  0.4
1997 Loudon RP, Benovic JL. Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6 Journal of Biological Chemistry. 272: 27422-27427. PMID 9341194 DOI: 10.1074/jbc.272.43.27422  0.4
1997 Krupnick JG, Gurevich VV, Benovic JL. Mechanism of quenching of phototransduction: Binding competition between arrestin and transducin for phosphorhodopsin Journal of Biological Chemistry. 272: 18125-18131. PMID 9218446 DOI: 10.1074/jbc.272.29.18125  0.4
1997 Wu G, Krupnick JG, Benovic JL, Lanier SM. Interaction of Arrestins with intracellular domains of muscarinic and α 2-adrenergic receptors Journal of Biological Chemistry. 272: 17836-17842. PMID 9211939 DOI: 10.1074/jbc.272.28.17836  0.4
1997 Gray-Keller MP, Detwiler PB, Benovic JL, Gurevich VV. Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion. Biochemistry. 36: 7058-63. PMID 9188704 DOI: 10.1021/bi963110k  0.4
1997 Mundell SJ, Benovic JL, Kelly E. A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization Molecular Pharmacology. 51: 991-998. PMID 9187265  0.4
1997 Krupnick JG, Goodman OB, Keen JH, Benovic JL. Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxyl terminus Journal of Biological Chemistry. 272: 15011-15016. PMID 9169476 DOI: 10.1074/jbc.272.23.15011  0.4
1997 Gros R, Benovic JL, Tan CM, Feldman RD. G-protein-coupled receptor kinase activity is increased in hypertension Journal of Clinical Investigation. 99: 2087-2093. PMID 9151780  0.4
1997 Gagnon AW, Benovic JL. Identification and chromosomal localization of a processed pseudogene of human GRK6 Gene. 184: 13-19. PMID 9016947 DOI: 10.1016/S0378-1119(96)00567-7  0.4
1997 Gurevich VV, Benovic JL. Mechanism of phosphorylation-recognition by visual arrestin and the transition of arrestin into a high affinity binding state Molecular Pharmacology. 51: 161-169. PMID 9016359  0.4
1997 Pronin AN, Benovic JL. Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C Journal of Biological Chemistry. 272: 3806-3812. PMID 9013639 DOI: 10.1074/jbc.272.6.3806  0.4
1997 Pronin AN, Satpaev DK, Slepak VZ, Benovic JL. Regulation of g protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain Faseb Journal. 11. DOI: 10.1074/jbc.272.29.18273  0.4
1997 Gagnon AW, Kallal L, Benovic JL. Role of arrestins in agonist-mediated downregulation of the 3 2-adrenergic receptor Faseb Journal. 11.  0.4
1997 Gurevichl VV, Gray-Keller MP, Detwiler PB, Benovic JL. Diverse functional roles of negatively charged residues in arrestin C-terminus Investigative Ophthalmology and Visual Science. 38: S22.  0.4
1997 Gray-Keller MP, Detwiler PB, Benovic JL, Gurevich VV. Single amino acid substitution in visual arrestin quenches light-activated rhodopsin Investigative Ophthalmology and Visual Science. 38: S22.  0.4
1997 Aiyar N, Pisa J, Dang K, Pronin AN, Benovic JL, Nambi P. Desensitization of recombinant porcine calcitonin gene-related peptide (CGRP) receptor: A possible role for G-protein-coupled receptor kinase 5 (GRK5) Faseb Journal. 11.  0.4
1996 Hosey MM, DebBurman SK, Pals-Rylaarsdam R, Richardson RM, Benovic JL. The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors. Progress in Brain Research. 109: 169-79. PMID 9009704  0.4
1996 Loudon RP, Perussia B, Benovic JL. Differentially regulated expression of the G-protein-coupled receptor kinases, βARK and GRK6, during myelomonocytic cell development in vitro Blood. 88: 4547-4557. PMID 8977246  0.4
1996 Penn RB, Frielle T, McCullough JR, Aberg G, Benovic JL. Comparison of R-, S-, and RS-Albuterol Interaction with Human β1- and β2-Adrenergic Receptors Clinical Reviews in Allergy and Immunology. 14: 37-45. PMID 8866170  0.4
1996 DebBurman SK, Ptasienski J, Benovic JL, Hosey MM. G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. The Journal of Biological Chemistry. 271: 22552-62. PMID 8798423 DOI: 10.1074/jbc.271.37.22552  0.4
1996 Palmer TM, Benovic JL, Stiles GL. Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors: Analysis of a chimeric A1-A3 adenosine receptor Journal of Biological Chemistry. 271: 15272-15278. PMID 8663009 DOI: 10.1074/jbc.271.25.15272  0.4
1996 Pronin AN, Benovic JL. The g protein-coupled receptor kinase grk5 is a target for regulation by PKC Faseb Journal. 10.  0.4
1996 Gurevich VV, Benovic JL. The mechanism of phosphorylation-recognition by visual arrestin: Phosphorylatiom-independent arrestin mutants Investigative Ophthalmology and Visual Science. 37.  0.4
1996 M-Zhang, Cofie DQ, Turnbaugh DT, Benovic JL, Patterson ES, Kem DC. The effect of ischemia on cardiac g-protein coupled receptor kinases Journal of Investigative Medicine. 44.  0.4
1995 Hosey MM, Benovic JL, DebBurman SK, Richardson RM. Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors. Life Sciences. 56: 951-5. PMID 10188798 DOI: 10.1016/0024-3205(95)00033-3  0.4
1995 Kelsen SG, Higgins NC, Zhou S, Mardini IA, Benovic JL. Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells. American Journal of Respiratory and Critical Care Medicine. 152: 1774-83. PMID 8520736 DOI: 10.1164/ajrccm.152.6.8520736  0.4
1995 Gurevich VV, Benovic JL. Visual arrestin binding to rhodopsin: Diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin Journal of Biological Chemistry. 270: 6010-6016. PMID 7890732  0.4
1995 DebBurman SK, Ptasienski J, Boetticher E, Lomasney JW, Benovic JL, Hosey MM. Lipid-mediated regulation of G protein-coupled receptor kinases 2 and 3. The Journal of Biological Chemistry. 270: 5742-7. PMID 7890702 DOI: 10.1074/jbc.270.11.5742  0.4
1995 Debburman SK, Kunapuli P, Benovic JL, Hosey MM. Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Molecular Pharmacology. 47: 224-33. PMID 7870029  0.4
1995 Prossnitz ER, Kim CM, Benovic JL, Ye RD. Phosphorylation of the N-formyl peptide receptor carboxyl terminus by the G protein-coupled receptor kinase, GRK2 Journal of Biological Chemistry. 270: 1130-1137. PMID 7836371 DOI: 10.1074/jbc.270.3.1130  0.4
1995 Saito M, Frielle T, Benovic JL, Ledeen RW. Modulation by GM1 ganglioside of β1-adrenergic receptor-induced cyclic AMP formation in Sf9 cells Bba - Molecular Cell Research. 1267: 1-5. PMID 7779864 DOI: 10.1016/0167-4889(95)00026-O  0.4
1995 Onorato JJ, Gillis ME, Liu Y, Benovic JL, Ruoho AE. The beta-adrenergic receptor kinase (GRK2) is regulated by phospholipids. The Journal of Biological Chemistry. 270: 21346-53. PMID 7673171 DOI: 10.1074/jbc.270.36.21346  0.4
1995 Pals-Rylaarsdam R, Xu Y, Witt-Enderby P, Benovic JL, Hosey MM. Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms Journal of Biological Chemistry. 270: 29004-29011. PMID 7499433 DOI: 10.1074/jbc.270.48.29004  0.4
1995 Palmer TM, Benovic JL, Stiles GL. Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor: Evidence for a G-protein-coupled receptor kinase-mediated mechanism Journal of Biological Chemistry. 270: 29607-29613. PMID 7494005 DOI: 10.1074/jbc.270.49.29607  0.4
1995 Sterne-Marr R, Benovic JL. Regulation of G Protein-Coupled Receptors by Receptor Kinases and Arrestins Vitamins and Hormones. 51: 193-234. DOI: 10.1016/S0083-6729(08)61039-0  0.4
1994 Kunapuli P, Onorato JJ, Hosey MM, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5 Journal of Biological Chemistry. 269: 1099-1105. PMID 8288567  0.4
1994 Penn RB, Benovic JL. Structure of the human gene encoding the beta-adrenergic receptor kinase. The Journal of Biological Chemistry. 269: 14924-30. PMID 8195124  0.4
1994 Kong G, Penn R, Benovic JL. A β-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the β2-adrenergic receptor Journal of Biological Chemistry. 269: 13084-13087. PMID 8175732  0.4
1994 Kunapuli P, Gurevich VV, Benovic JL. Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5 Journal of Biological Chemistry. 269: 10209-10212. PMID 8144599  0.4
1994 Gurevich VV, Chen CY, Kim CM, Benovic JL. Visual arrestin binding to rhodopsin: Intramolecular interaction between the basic N terminus and acidic C terminus of arrestin may regulate binding selectivity Journal of Biological Chemistry. 269: 8721-8727. PMID 8132602  0.4
1994 Krupnick JG, Gurevich VV, Schepers T, Hamm HE, Benovic JL. Arrestin-rhodopsin interaction: Multi-site binding delineated by peptide inhibition Journal of Biological Chemistry. 269: 3226-3232. PMID 8106358  0.4
1994 Loudon RP, Benovic JL. Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6 Journal of Biological Chemistry. 269: 22691-22697. PMID 8077221  0.4
1994 Kelsen SG, Zhou S, Anakwe O, Mardini I, Higgins N, Benovic JL. Expression of the β-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells American Journal of Physiology - Lung Cellular and Molecular Physiology. 267. PMID 7943348  0.4
1994 Penn RB, Kelsen SG, Benovic JL. Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells American Journal of Respiratory Cell and Molecular Biology. 11: 496-505. PMID 7917318  0.4
1994 Mardini IA, Higgins NC, Zhou S, Benovic JL, Kelsen SG. Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 11: 287-95. PMID 7916196 DOI: 10.1165/ajrcmb.11.3.7916196  0.4
1994 Kelsen SG, Zhou Shuangwen, Anakwe O, Mardini I, Higgins N, Benovic JL. Expression of the beta-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells Am.J.Physiol.. 267.  0.4
1993 Richardson RM, Kim C, Benovic JL, Hosey MM. Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the β-adrenergic receptor kinase Journal of Biological Chemistry. 268: 13650-13656. PMID 8514797  0.4
1993 Gurevich VV, Benovic JL. Visual arrestin interaction with rhodopsin: Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin Journal of Biological Chemistry. 268: 11628-11638. PMID 8505295  0.4
1993 Ramkumar V, Kwatra M, Benovic JL, Stilesa GL. Functional consequences of A1 adenosine-receptor phosphorylation by the β-adrenergic receptor kinase Bba - Molecular Cell Research. 1179: 89-97. PMID 8399355 DOI: 10.1016/0167-4889(93)90075-Z  0.4
1993 Kim CM, Dion SB, Onorato JJ, Benovic JL. Expression and characterization of two beta-adrenergic receptor kinase isoforms using the baculovirus expression system Receptor. 3: 39-55. PMID 8394172  0.4
1993 Kim CM, Dion SB, Benovic JL. Mechanism of β-adrenergic receptor kinase activation by G proteins Journal of Biological Chemistry. 268: 15412-15418. PMID 8393441  0.4
1993 Benovic JL, Gomez J. Molecular cloning and expression of GRK6: A new member of the G protein-coupled receptor kinase family Journal of Biological Chemistry. 268: 19521-19527. PMID 8366096  0.4
1993 Gurevich VV, Richardson RM, Kim CM, Hosey MM, Benovic JL. Binding of wild type and chimeric arrestins to the m2 muscarinic cholinergic receptor Journal of Biological Chemistry. 268: 16879-16882. PMID 8349577  0.4
1993 Chen CY, Dion SB, Kim CM, Benovic JL. β-Adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation Journal of Biological Chemistry. 268: 7825-7831. PMID 8096517  0.4
1993 Kunapuli P, Benovic JL. Cloning and expression of GRK5: A member of the G protein-coupled receptor kinase family Proceedings of the National Academy of Sciences of the United States of America. 90: 5588-5592. PMID 7685906  0.4
1992 Gurevich VV, Benovic JL. Cell-free expression of visual arrestin: Truncation mutagenesis identifies multiple domains involved in rhodopsin interaction Journal of Biological Chemistry. 267: 21919-21923. PMID 1400502  0.4
1992 Gomez J, Benovic JL. Molecular and regulatory properties of the adenylyl cyclase-coupled β-adrenergic receptors International Review of Cytology. 137: 1-34. PMID 1336003  0.4
1992 Kelsen SG, Mardini IA, Zhou S, Benovic JL, Higgins NC. A technique to harvest viable tracheobronchial epithelial cells from living human donors. American Journal of Respiratory Cell and Molecular Biology. 7: 66-72. PMID 1320903 DOI: 10.1165/ajrcmb/7.1.66  0.4
1991 Benovic JL, Stone WC, Huebner K, Croce C, Caron MG, Lefkowitz RJ. cDNA cloning and chromosomal localization of the human α-adrenergic receptor kinase Febs Letters. 283: 122-126. PMID 2037065 DOI: 10.1016/0014-5793(91)80568-N  0.4
1991 Palczewskl K, Benovic JL. G-protein-coupled receptor kinases Trends in Biochemical Sciences. 16: 387-391. PMID 1664548 DOI: 10.1016/0968-0004(91)90157-Q  0.4
1991 Benovic JL. Purification and characterization of β-adrenergic receptor kinase Methods in Enzymology. 200: 351-362. PMID 1659657 DOI: 10.1016/0076-6879(91)00152-M  0.4
1991 Yang SD, Benovic JL, Fong YL, Caron MG, Lefkowitz RJ. Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase) Biochemical and Biophysical Research Communications. 178: 1306-1311. PMID 1651717 DOI: 10.1016/0006-291X(91)91036-C  0.4
1990 Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406  0.4
1990 Lohse MJ, Benovic JL, Codina J, Caron MG, Lefkowitz RJ. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science (New York, N.Y.). 248: 1547-50. PMID 2163110  0.4
1990 Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors. The Journal of Biological Chemistry. 265: 3202-11. PMID 2154473  0.4
1990 Benovic JL, Onorato JJ, Caron MG, Lefkowitz RJ. Regulation of G protein-coupled receptors by agonist-dependent phosphorylation Journal of General Physiology. 87-103.  0.4
1989 Kwatra MM, Benovic JL, Caron MG, Lefkowitz RJ, Hosey MM. Phosphorylation of chick heart muscarinic cholinergic receptors by the β-adrenergic receptor kinase Biochemistry. 28: 4543-4547. PMID 2765501  0.4
1989 Benovic JL, DeBlasi A, Stone WC, Caron MG, Lefkowitz RJ. Β-adrenergic receptor kinase: Primary structure delineates a multigene family Science. 246: 235-240. PMID 2552582  0.4
1989 Lohse MJ, Lefkowitz RJ, Caron MG, Benovic JL. Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3011-5. PMID 2541428  0.4
1989 Benovic JL, Stone WC, Caron MG, Lefkowitz RJ. Inhibition of the β-adrenergic receptor kinase by polyanions Journal of Biological Chemistry. 264: 6707-6710. PMID 2468660  0.4
1988 Krupinski J, Rajaram R, Lakonishok M, Benovic JL, Cerione RA. Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles Journal of Biological Chemistry. 263: 12333-12341. PMID 3137226  0.4
1988 Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/annurev.cb.04.110188.002201  0.4
1988 Strasser RH, Benovic JL, Lefkowitz RJ, Caron MG. The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells Advances in Experimental Medicine and Biology. 231: 503-517. PMID 2843012  0.4
1988 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. Endocrine Reviews. 9: 38-56. PMID 2836188 DOI: 10.1210/edrv-9-1-38  0.4
1988 Benovic JL, Staniszewski C, Mayor F, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation Journal of Biological Chemistry. 263: 3893-3897. PMID 2831211  0.4
1987 Benovic JL, Mayor F, Staniszewski C, Lefkowitz RJ, Caron MG. Purification and characterization of the beta-adrenergic receptor kinase Journal of Biological Chemistry. 262: 9026-9032. PMID 3036840  0.4
1987 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of transmembrane signaling by receptor phosphorylation. Cell. 48: 913-22. PMID 3030559 DOI: 10.1016/0092-8674(87)90700-8  0.4
1987 Bouvier M, Leeb-Lundberg LM, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 262: 3106-13. PMID 3029101  0.4
1987 Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989  0.4
1987 Mayor F, Benovic JL, Caron MG, Lefkowitz RJ. Somatostatin induces translocation of the β-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells Journal of Biological Chemistry. 262: 6468-6471. PMID 2883186  0.4
1987 Sibley DR, Benovic JL, Caron MG, Lefkowitz RJ. Molecular mechanisms of beta-adrenergic receptor desensitization. Advances in Experimental Medicine and Biology. 221: 253-73. PMID 2829583  0.4
1987 Benovic JL, Kühn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) Proceedings of the National Academy of Sciences of the United States of America. 84: 8879-8882. PMID 2827157  0.4
1987 Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ. The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. The Journal of Biological Chemistry. 262: 14282-8. PMID 2821000  0.4
1987 Benovic JL, Lefkowitz RJ. 10 Regulation of Receptor Function Enzymes. 18: 319-333. DOI: 10.1016/S1874-6047(08)60261-9  0.4
1986 Sibley DR, Strasser RH, Benovic JL, Daniel K, Lefkowitz RJ. Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. Proceedings of the National Academy of Sciences of the United States of America. 83: 9408-12. PMID 3025843  0.4
1986 Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ. β-Agonist- and prostaglandin E1-induced translocation of the β-adrenergic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors Proceedings of the National Academy of Sciences of the United States of America. 83: 6362-6366. PMID 3018728  0.4
1986 Benovic JL, Mayor F, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase Nature. 321: 869-872. PMID 3014340 DOI: 10.1038/321869a0  0.4
1986 Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. β-Adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor Proceedings of the National Academy of Sciences of the United States of America. 83: 2797-2801. PMID 2871555  0.4
1986 Lefkowitz RJ, Benovic JL, Kobilka B, Caron MG. β-Adrenergic receptors and rhodopsin: shedding new light on an old subject Trends in Pharmacological Sciences. 7: 444-448. DOI: 10.1016/0165-6147(86)90417-7  0.4
1984 Stiles GL, Benovic JL, Caron MG, Lefkowitz RJ. Mammalian β-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains Journal of Biological Chemistry. 259: 8655-8663. PMID 6330118  0.4
1984 Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763  0.4
1984 Benovic JL, Shorr RGL, Caron MG, Lefkowitz RJ. The mammalian β2-adrenergic receptor: Purification and characterization Biochemistry. 23: 4510-4518. PMID 6093858  0.4
1984 Benovic JL, Cerione RA, Codina J. Deglycosylation of the pure β-adrenergic receptor Federation Proceedings. 43.  0.4
1984 Pike LJ, Benovic JL, Caron MG, Lefkowitz RJ. Isoproterenol enhances phosphorylation of pure β-adrenergic receptor by cAMP-dependent protein kinase Federation Proceedings. 43.  0.4
1983 Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562a0  0.4
1983 Benovic JL, Stiles GL, Lefkowitz RJ, Caron MG. Photoaffinity labelling of mammalian beta-adrenergic receptors: Metal-dependent proteolysis explains apparent heterogeneity Biochemical and Biophysical Research Communications. 110: 504-511. PMID 6301455 DOI: 10.1016/0006-291X(83)91178-6  0.4
1982 Benovic JL, Shorr RGL, Heald SL. Purification and photoaffinity labelling of a mammalian β2 adrenergic receptor Federation Proceedings. 5205.  0.4
1981 Li TM, Benovic JL, Buckler RT, Burd JF. Homogeneous substrate-labeled fluorescent immunoassay for theophylline in serum Clinical Chemistry. 27: 22-26. PMID 7449119  0.4
1981 Li TM, Benovic JL, Burd JF. Serum theophylline determination by fluorescence polarization immunoassay utilizing an umbelliferone derivative as a fluorescent label Biophysical Journal. 33. DOI: 10.1016/0003-2697(81)90163-9  0.4
1979 Dunaway-Mariano D, Benovic JL, Cleland WW, Gupta RK, Mildvan AS. Stereospecificity of the metal-adenosine 5′-triphosphate complex in reactions of muscle pyruvate kinase Biochemistry. 18: 4347-4354. PMID 486426  0.4
1979 Gupta RK, Benovic JL, Rose ZB. Location of the allosteric site for 2,3-bisphosphoglycerate on human oxy- and deoxyhemoglobin as observed by magnetic resonance spectroscopy. The Journal of Biological Chemistry. 254: 8250-5. PMID 224047  0.4
1978 Gupta RK, Benovic JL. Magnetic resonance studies of the interaction of divalent metal cations with 2,3-bisphosphoglycerate Biochemical and Biophysical Research Communications. 84: 130-137. PMID 728120 DOI: 10.1016/0006-291X(78)90273-5  0.4
1978 Gupta RK, Benovic JL. Magnetic resonance and kinetic studies of the spatial arrangement of phosphoenolpyruvate and chromium (III)-adenosine diphosphate at the catalytic site of pyruvate kinase Journal of Biological Chemistry. 253: 8878-8886. PMID 721820  0.4
1978 Gupta RK, Benovic JL, Rose ZB. The determination of the free magnesium level in the human red blood cell by 31P NMR. The Journal of Biological Chemistry. 253: 6172-6. PMID 687387  0.4
1978 Gupta RK, Benovic JL, Rose ZB. Magnetic resonance studies of the binding of ATP and cations to human hemoglobin. The Journal of Biological Chemistry. 253: 6165-71. PMID 210170  0.4
1978 Benovic JL, Ferretti JA, Gupta RK. Carbon 13 NMR and metal binding properties of bleomycin Biophysical Journal. 21.  0.4
1978 Gupta RK, Benovic JL, Pesando JM. 1H NMR studies of neocarzinostatin (NCS) Biophysical Journal. 21.  0.4
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