| Year |
Citation |
Score |
| 2014 |
Weiland MH, Qian Y, Sodetz JM. Membrane pore formation by human complement: functional importance of the transmembrane β-hairpin (TMH) segments of C8α and C9. Molecular Immunology. 57: 310-6. PMID 24239861 DOI: 10.1016/J.Molimm.2013.10.007 |
0.81 |
|
| 2011 |
Lovelace LL, Cooper CL, Sodetz JM, Lebioda L. Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. The Journal of Biological Chemistry. 286: 17585-92. PMID 21454577 DOI: 10.1074/Jbc.M111.219766 |
0.695 |
|
| 2011 |
Lebioda L, Lovelace LL, Cooper CL, Sodetz JM. Structure of human C8 suggests how complement forms circular membrane pores Acta Crystallographica Section a Foundations of Crystallography. 67: C544-C544. DOI: 10.1107/S0108767311086259 |
0.446 |
|
| 2008 |
Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM. Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit. Journal of Molecular Biology. 379: 331-42. PMID 18440555 DOI: 10.1016/J.Jmb.2008.03.061 |
0.834 |
|
| 2008 |
Lovelace LL, Chiswell B, Slade DJ, Sodetz JM, Lebioda L. Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding. Molecular Immunology. 45: 750-6. PMID 17692377 DOI: 10.1016/J.Molimm.2007.06.359 |
0.826 |
|
| 2007 |
Chiswell B, Lovelace LL, Brannen C, Ortlund EA, Lebioda L, Sodetz JM. Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family. Biochimica Et Biophysica Acta. 1774: 637-44. PMID 17452033 DOI: 10.1016/J.Bbapap.2007.03.004 |
0.771 |
|
| 2007 |
Brannen CL, Sodetz JM. Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain. Molecular Immunology. 44: 960-5. PMID 16624411 DOI: 10.1016/J.Molimm.2006.03.012 |
0.873 |
|
| 2006 |
Chiswell B, Slade DJ, Sodetz JM. Binding of the lipocalin C8gamma to human complement protein C8alpha is mediated by loops located at the entrance to the C8gamma ligand binding site. Biochimica Et Biophysica Acta. 1764: 1518-24. PMID 16935577 DOI: 10.1016/J.Bbapap.2006.07.003 |
0.837 |
|
| 2006 |
Slade DJ, Chiswell B, Sodetz JM. Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9. Biochemistry. 45: 5290-6. PMID 16618117 DOI: 10.1021/Bi0601860 |
0.838 |
|
| 2002 |
Scibek JJ, Plumb ME, Sodetz JM. Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit. Biochemistry. 41: 14546-51. PMID 12463754 DOI: 10.1021/Bi026641J |
0.848 |
|
| 2002 |
Parker CL, Sodetz JM. Role of the human C8 subunits in complement-mediated bacterial killing: Evidence that C8γ is not essential Molecular Immunology. 39: 453-458. PMID 12413696 DOI: 10.1016/S0161-5890(02)00121-9 |
0.783 |
|
| 2002 |
Musingarimi P, Plumb ME, Sodetz JM. Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain. Biochemistry. 41: 11255-60. PMID 12220191 DOI: 10.1021/Bi026207H |
0.867 |
|
| 2002 |
Ortlund E, Parker CL, Schreck SF, Ginell S, Minor W, Sodetz JM, Lebioda L. Crystal structure of human complement protein C8γ at 1.2 Å resolution reveals a lipocalin fold and a distinct ligand binding site Biochemistry. 41: 7030-7037. PMID 12033936 DOI: 10.1021/Bi025696I |
0.767 |
|
| 2000 |
Schreck SF, Parker C, Plumb ME, Sodetz JM. Human complement protein C8γ Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1482: 199-208. PMID 11058761 DOI: 10.1016/S0167-4838(00)00155-2 |
0.813 |
|
| 2000 |
Plumb ME, Sodetz JM. An indel within the C8α subunit of human complement C8 mediates intracellular binding of C8γ and formation of C8α-γ Biochemistry. 39: 13078-13083. PMID 11041874 DOI: 10.1021/Bi001451Z |
0.748 |
|
| 1999 |
Plumb ME, Scibek JJ, Barber TD, Dunlap RJ, Platteborze PL, Sodetz JM. Chimeric and truncated forms of human complement protein C8 alpha reveal binding sites for C8 beta and C8 gamma within the membrane attack complex/perforin region. Biochemistry. 38: 8478-84. PMID 10387094 DOI: 10.1021/Bi9904858 |
0.834 |
|
| 1998 |
Schreck SF, Plumb ME, Platteborze PL, Kaufman KM, Michelotti GA, Letson CS, Sodetz JM. Expression and characterization of recombinant subunits of human complement component C8: Further analysis of the function of C8α and C8γ Journal of Immunology. 161: 311-318. PMID 9647238 |
0.569 |
|
| 1998 |
Plumb M, Scibek J, Barber T, Dunlap R, Platteborze P, Sodetz J. Characterization of truncated and chimeric forms of recombinant human C8 reveal the location of binding sites in the C8α subunit Molecular Immunology. 35: 402. DOI: 10.1016/S0161-5890(98)90820-3 |
0.832 |
|
| 1996 |
Letson CS, Kaufman KM, Sodetz JM. In vitro expression of the beta subunit of human complement component C8 Molecular Immunology. 33: 1295-1300. PMID 9171889 DOI: 10.1016/S0161-5890(96)00108-3 |
0.524 |
|
| 1996 |
Platteborze PL, Hobart MJ, Sodetz JM. Physical linkage and orientation of the human complement C8α and C8β genes on chromosome 1p32 Human Genetics. 98: 443-446. PMID 8792819 DOI: 10.1007/S004390050236 |
0.452 |
|
| 1995 |
Michelotti GA, Snider JV, Sodetz JM. Genomic organization of human complement protein C8α and further examination of its linkage to C8β Human Genetics. 95: 513-518. PMID 7759071 DOI: 10.1007/Bf00223862 |
0.486 |
|
| 1995 |
Zhang L, Rittner C, Sodetz JM, Schneider PM, Kaufmann T. The eighth component of human complement: molecular basis of C8A (C81) polymorphism Human Genetics. 96: 281-284. PMID 7649542 DOI: 10.1007/Bf00210407 |
0.323 |
|
| 1995 |
Lockert DH, Kaufman KM, Chang CP, Husler T, Sodetz JM, Sims PJ. Identity of the segment of human complement C8 recognized by complement regulatory protein CD59 Journal of Biological Chemistry. 270: 19723-19728. PMID 7544344 DOI: 10.1074/Jbc.270.34.19723 |
0.54 |
|
| 1995 |
Husler T, Lockert DH, Kaufman KM, Sodetz JM, Sims PJ. Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59 Journal of Biological Chemistry. 270: 3483-3486. PMID 7533152 DOI: 10.1074/Jbc.270.8.3483 |
0.532 |
|
| 1994 |
Kaufman KM, Sodetz JM. Genomic structure of the human complement protein C8γ: Homology to the lipocalin gene family Biochemistry. 33: 5162-5166. PMID 8172891 DOI: 10.1021/Bi00183A020 |
0.603 |
|
| 1994 |
White RV, Kaufman KM, Letson CS, Platteborze PL, Sodetz JM. Characterization of rabbit complement component C8: Functional evidence for the species-selective recognition of C8α by homologous restriction factor (CD59) Journal of Immunology. 152: 2501-2509. PMID 7510745 |
0.501 |
|
| 1992 |
Theriault A, Boyd E, Whaley K, Sodetz JM, Connor JM. Regional chromosomal assignment of genes encoding the α and β subunits of human complement protein C8 to 1p32 Human Genetics. 88: 703-704. PMID 1551680 DOI: 10.1007/Bf02265304 |
0.41 |
|
| 1991 |
Komatsu M, Yamamoto KI, Mikami H, Sodetz JM. Genetic deficiency of complement component C8 in the rabbit: Evidence of a translational defect in expression of the α-γ subunit Biochemical Genetics. 29: 271-274. PMID 1772398 DOI: 10.1007/Bf00590107 |
0.339 |
|
| 1990 |
Dave SJ, Sodetz JM. Regulation of the membrane attack complex of complement. Evidence that C8γ is not the target of homologous restriction factors Journal of Immunology. 144: 3087-3090. PMID 2324496 |
0.565 |
|
| 1990 |
Snider JV, Kaufman KM, Sodetz JM. Chromosomal assignment and physical linkage of the human C8 loci: Implications regarding C8 polymorphisms and deficiencies Complement and Inflammation. 7: 298-301. PMID 2088669 DOI: 10.1159/000463164 |
0.329 |
|
| 1989 |
Sodetz JM. Structure and function of C8 in the membrane attack sequence of complement Current Topics in Microbiology and Immunology. 140: 19-31. PMID 2644073 DOI: 10.1007/978-3-642-73911-8_3 |
0.697 |
|
| 1989 |
Kaufman KM, Snider JV, Spurr NK, Schwartz CE, Sodetz JM. Chromosomal assignment of genes encoding the α, β, and γ subunits of human complement protein C8: Identification of a close physical linkage between the α and the β loci Genomics. 5: 475-480. PMID 2613233 DOI: 10.1016/0888-7543(89)90012-8 |
0.312 |
|
| 1988 |
Esser AF, Sodetz JM. Membrane attack complex proteins C5b-6, C7, C8, and C9 of human complement Methods in Enzymology. 162: 551-578. PMID 3226325 DOI: 10.1016/0076-6879(88)62103-3 |
0.624 |
|
| 1987 |
Ng SC, Gururaj Rao A, Zack Howard OM, Sodetz JM. The eighth component of human complement: Evidence that it is an oligomeric serum protein assembled from products of three different genes Biochemistry. 26: 5229-5233. PMID 3676249 DOI: 10.1021/Bi00391A003 |
0.341 |
|
| 1987 |
Stewart JL, Kolb WP, Sodetz JM. Evidence that C5b recognizes and mediates C8 incorporation into the cytolytic complex of complement. Journal of Immunology (Baltimore, Md. : 1950). 139: 1960-4. PMID 3624872 |
0.648 |
|
| 1987 |
Howard OMZ, Rao AG, Sodetz JM. Complementary DNA and derived amino acid sequence of the β subunit of human complement protein C8: Identification of a close structural and ancestral relationship to the α subunit and C9 Biochemistry. 26: 3565-3570. PMID 2820472 |
0.339 |
|
| 1987 |
Rao AG, Howard OMZ, Ng SC, Whitehead AS, Colten HR, Sodetz JM. Complementary DNA and derived amino acid sequence of the α subunit of human complement protein C8: Evidence for the existence of a separate α subunit messenger RNA Biochemistry. 26: 3556-3564. PMID 2820471 |
0.313 |
|
| 1985 |
Brickner A, Sodetz JM. Functional domains of the α subunit of the eighth component of human complement: Identification and characterization of a distinct binding site for the γ chain Biochemistry. 24: 4603-4607. PMID 4063342 DOI: 10.1021/Bi00338A019 |
0.531 |
|
| 1985 |
Stewart JL, Sodetz JM. Analysis of the specific association of the eighth and ninth components of human complement: identification of a direct role for the alpha subunit of C8. Biochemistry. 24: 4598-602. PMID 4063341 DOI: 10.1021/Bi00338A018 |
0.545 |
|
| 1985 |
Brickner A, Sodetz JM. Binding studies using the purified (γ) chain of human C8 reveal that it is located on the surface of membrane-bound C5b-8 and C5b-9 Federation Proceedings. 44. |
0.505 |
|
| 1985 |
Stewart JL, Sodetz JM. Analysis of the specific association of the eighth and ninth components of human complement: Identification of a direct role for the α subunit of C8 Biochemistry. 24: 4598-4602. |
0.43 |
|
| 1985 |
Stewart JL, Sodetz JM. Specific association of human C8 and C9 in solution occurs through the α subunit C8 Federation Proceedings. 44. |
0.503 |
|
| 1985 |
Ng S, Sodetz JM. Biosynthesis of the eigth component of complement (C8) by isolated hepatocytes Federation Proceedings. 44. |
0.392 |
|
| 1984 |
Brickner A, Sodetz JM. Function of subunits within the eighth component of human complement: Selective removal of the γ chain reveals it has no direct role in cytolysis Biochemistry. 23: 832-837. PMID 6712927 DOI: 10.1021/Bi00300A008 |
0.647 |
|
| 1984 |
Stewart JL, Monahan JB, Brickner A, Sodetz JM. Measurement of the ratio of the eighth and ninth components of human complement on complement-lysed membranes. Biochemistry. 23: 4016-22. PMID 6487588 DOI: 10.1021/Bi00313A002 |
0.633 |
|
| 1984 |
Brickner A, Sodetz JM. The eight component of human complement (C8): Influence of the γ subunit on the affinity of C8 for membrane-bound C5b-7 Federation Proceedings. 43. |
0.582 |
|
| 1984 |
Stewart JL, Monahan JB, Brickner A, Sodetz JM. Measurement of the ratio of the eighth and ninth components of human complement on complement-lysed membranes Biochemistry. 23: 4016-4022. |
0.561 |
|
| 1983 |
Monahan JB, Stewart JL, Sodetz JM. Studies of the association of the eighth and ninth components of human complement within the membrane-bound cytolytic complex. The Journal of Biological Chemistry. 258: 5056-62. PMID 6833292 |
0.591 |
|
| 1983 |
Steckel EW, Welbaum BE, Sodetz JM. Evidence of direct insertion of terminal complement proteins into cell membrane bilayers during cytolysis. Labeling by a photosensitive membrane probe reveals a major role for the eighth and ninth components Journal of Biological Chemistry. 258: 4318-4324. PMID 6833260 |
0.386 |
|
| 1982 |
Pickering RJ, Rynes RI, LoCascio N, Monahan JB, Sodetz JM. Identification of the alpha-gamma subunit of the eighth component of complement (C8) in a patient with systemic lupus erythematosus and absent C8 activity: patients and family studies. Clinical Immunology and Immunopathology. 23: 323-34. PMID 7105499 DOI: 10.1016/0090-1229(82)90118-0 |
0.558 |
|
| 1982 |
Monahan J, Welbaum B, Sodetz J. Studies of the interaction of C8 and C9 within the membrane-bound cytolytic complex of complement Molecular Immunology. 19: 1403. DOI: 10.1016/0161-5890(82)90155-9 |
0.517 |
|
| 1981 |
Monahan JB, Sodetz JM. Role of the beta subunit in interaction of the eighth component of human complement with the membrane-bound cytolytic complex. The Journal of Biological Chemistry. 256: 3258-62. PMID 7204401 |
0.57 |
|
| 1980 |
Steckel EW, York RG, Monahan JB, Sodetz JM. The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure. The Journal of Biological Chemistry. 255: 11997-2005. PMID 7440581 |
0.378 |
|
| 1980 |
Monahan JB, Sodetz JM. Binding of the eighth component of human complement to the soluble cytolytic complex is mediated by its beta subunit. The Journal of Biological Chemistry. 255: 10579-82. PMID 7430137 |
0.574 |
|
| 1978 |
Sodetz JM, Paulson JC, Pizzo SV, McKee PA. Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. The Journal of Biological Chemistry. 253: 7202-6. PMID 100492 |
0.343 |
|
| 1975 |
Castellino FJ, Schick LA, Brockway WJ, Sodetz JM. The activation and inhibition of fibrinolysis Advances in Experimental Medicine and Biology. 63: 233-243. PMID 128278 DOI: 10.1007/978-1-4684-3258-9_15 |
0.33 |
|
| 1975 |
Violand BN, Sodetz JM, Castellino FJ. The effect of ε{lunate}-amino caproic acid on the gross conformation of plasminogen and plasmin Archives of Biochemistry and Biophysics. 170: 300-305. PMID 126043 DOI: 10.1016/0003-9861(75)90121-6 |
0.44 |
|
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