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Antonio J. Pagan, Ph.D. - Publications

Affiliations: 
2012 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Cell Biology
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pagán AJ, Lee LJ, Edwards-Hicks J, Moens CB, Tobin DM, Busch-Nentwich EM, Pearce EL, Ramakrishnan L. mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity. Cell. 185: 3720-3738.e13. PMID 36103894 DOI: 10.1016/j.cell.2022.08.018  0.696
2022 Osman MM, Shanahan JK, Chu F, Takaki KK, Pinckert ML, Pagán AJ, Brosch R, Conrad WH, Ramakrishnan L. The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122161119. PMID 35271388 DOI: 10.1073/pnas.2122161119  0.596
2021 Whitworth LJ, Troll R, Pagán AJ, Roca FJ, Edelstein PH, Troll M, Tobin DM, Phu NH, Bang ND, Thwaites GE, Thuong NTT, Sewell RF, Ramakrishnan L. Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33658385 DOI: 10.1073/pnas.2024852118  0.689
2021 Takaki KK, Roca FJ, Schramm G, Wilbers RHP, Ittiprasert W, Brindley PJ, Rinaldi G, Berriman M, Ramakrishnan L, Pagán AJ. Tumor Necrosis Factor and Schistosoma mansoni egg antigen omega-1 shape distinct aspects of the early egg-induced granulomatous response. Plos Neglected Tropical Diseases. 15: e0008814. PMID 33465071 DOI: 10.1371/journal.pntd.0008814  0.62
2020 Takaki KK, Rinaldi G, Berriman M, Pagán AJ, Ramakrishnan L. Schistosoma mansoni Eggs Modulate the Timing of Granuloma Formation to Promote Transmission. Cell Host & Microbe. PMID 33120115 DOI: 10.1016/j.chom.2020.10.002  0.591
2020 Osman MM, Pagán AJ, Shanahan JK, Ramakrishnan L. Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage. Plos One. 15: e0233252. PMID 32701962 DOI: 10.1371/Journal.Pone.0233252  0.618
2018 Pagán AJ, Ramakrishnan L. The Formation and Function of Granulomas. Annual Review of Immunology. PMID 29400999 DOI: 10.1146/Annurev-Immunol-032712-100022  0.65
2017 Pagán AJ, Ramakrishnan L. TORmented macrophages spontaneously form granulomas. Nature Immunology. 18: 252-253. PMID 28198828 DOI: 10.1038/Ni.3689  0.601
2016 Tubo NJ, Fife BT, Pagan AJ, Kotov DI, Goldberg MF, Jenkins MK. Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection. Science (New York, N.Y.). 351: 511-4. PMID 26823430 DOI: 10.1126/Science.Aad0483  0.665
2015 Pagán AJ, Yang CT, Cameron J, Swaim LE, Ellett F, Lieschke GJ, Ramakrishnan L. Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host & Microbe. 18: 15-26. PMID 26159717 DOI: 10.1016/J.Chom.2015.06.008  0.631
2014 Peters NC, Pagán AJ, Lawyer PG, Hand TW, Henrique Roma E, Stamper LW, Romano A, Sacks DL. Chronic parasitic infection maintains high frequencies of short-lived Ly6C+CD4+ effector T cells that are required for protection against re-infection. Plos Pathogens. 10: e1004538. PMID 25473946 DOI: 10.1371/Journal.Ppat.1004538  0.512
2014 Pagán AJ, Ramakrishnan L. Immunity and Immunopathology in the Tuberculous Granuloma. Cold Spring Harbor Perspectives in Medicine. PMID 25377142 DOI: 10.1101/Cshperspect.A018499  0.644
2013 Tubo NJ, Pagán AJ, Taylor JJ, Nelson RW, Linehan JL, Ertelt JM, Huseby ES, Way SS, Jenkins MK. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell. 153: 785-96. PMID 23663778 DOI: 10.1016/J.Cell.2013.04.007  0.748
2013 Pagán AJ, Peters NC, Debrabant A, Ribeiro-Gomes F, Pepper M, Karp CL, Jenkins MK, Sacks DL. Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice. European Journal of Immunology. 43: 427-38. PMID 23109292 DOI: 10.1002/Eji.201242715  0.672
2012 Hand TW, Dos Santos LM, Bouladoux N, Molloy MJ, Pagán AJ, Pepper M, Maynard CL, Elson CO, Belkaid Y. Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses. Science (New York, N.Y.). 337: 1553-6. PMID 22923434 DOI: 10.1126/Science.1220961  0.537
2012 Pagán AJ, Pepper M, Chu HH, Green JM, Jenkins MK. CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs. Journal of Immunology (Baltimore, Md. : 1950). 189: 2909-17. PMID 22896637 DOI: 10.4049/Jimmunol.1103231  0.644
2012 Srivastava R, Burbach BJ, Mitchell JS, Pagán AJ, Shimizu Y. ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathways. Molecular and Cellular Biology. 32: 1908-17. PMID 22411628 DOI: 10.1128/Mcb.06541-11  0.431
2011 Pepper M, Pagán AJ, Igyártó BZ, Taylor JJ, Jenkins MK. Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity. 35: 583-95. PMID 22018468 DOI: 10.1016/J.Immuni.2011.09.009  0.721
2010 Vang KB, Yang J, Pagán AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. Journal of Immunology (Baltimore, Md. : 1950). 184: 4074-7. PMID 20228198 DOI: 10.4049/Jimmunol.0903933  0.326
2010 DeNucci CC, Pagán AJ, Mitchell JS, Shimizu Y. Control of alpha4beta7 integrin expression and CD4 T cell homing by the beta1 integrin subunit. Journal of Immunology (Baltimore, Md. : 1950). 184: 2458-67. PMID 20118278 DOI: 10.4049/Jimmunol.0902407  0.368
2010 Pepper M, Linehan JL, Pagán AJ, Zell T, Dileepan T, Cleary PP, Jenkins MK. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nature Immunology. 11: 83-9. PMID 19935657 DOI: 10.1038/Ni.1826  0.758
2009 Hondowicz BD, Batheja AO, Metzgar MH, Pagán AJ, Perng OA, Willms S, Caton AJ, Erikson J. Efficient help for autoreactive B-cell activation requires CD4+ T-cell recognition of an agonist peptide at the effector stage. European Journal of Immunology. 39: 2377-82. PMID 19662636 DOI: 10.1002/Eji.200939471  0.457
2009 Moon JJ, Chu HH, Hataye J, Pagán AJ, Pepper M, McLachlan JB, Zell T, Jenkins MK. Tracking epitope-specific T cells. Nature Protocols. 4: 565-81. PMID 19373228 DOI: 10.1038/Nprot.2009.9  0.737
2007 Hondowicz BD, Alexander ST, Quinn WJ, Pagán AJ, Metzgar MH, Cancro MP, Erikson J. The role of BLyS/BLyS receptors in anti-chromatin B cell regulation. International Immunology. 19: 465-75. PMID 17369193 DOI: 10.1093/Intimm/Dxm011  0.405
2006 Pagán AJ, Ramón HE, Hondowicz BD, Erikson J. T cell-mediated activation and regulation of anti-chromatin B cells. Autoimmunity Reviews. 5: 373-6. PMID 16890889 DOI: 10.1016/J.Autrev.2005.10.011  0.513
2003 Allman D, Sambandam A, Kim S, Miller JP, Pagan A, Well D, Meraz A, Bhandoola A. Thymopoiesis independent of common lymphoid progenitors. Nature Immunology. 4: 168-74. PMID 12514733 DOI: 10.1038/Ni878  0.378
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