| Year |
Citation |
Score |
| 2024 |
Godet I, Oza HH, Shi Y, Joe NS, Weinstein AG, Johnson J, Considine M, Talluri S, Zhang J, Xu R, Doctorman S, Mbulaiteye D, Stein-O'Brien G, Kagohara LT, Santa-Maria CA, ... ... Gilkes DM, et al. Hypoxia induces ROS-resistant memory upon reoxygenation in vivo promoting metastasis in part via MUC1-C. Nature Communications. 15: 8416. PMID 39341835 DOI: 10.1038/s41467-024-51995-2 |
0.832 |
|
| 2024 |
Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL. Retraction: Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis. Cancer Research. 84: 2927. PMID 39228257 DOI: 10.1158/0008-5472.CAN-24-2214 |
0.851 |
|
| 2024 |
Samanta D, Park Y, Andrabi SA, Shelton LM, Gilkes DM, Semenza GL. Retraction: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis. Cancer Research. 84: 2926. PMID 39228256 DOI: 10.1158/0008-5472.CAN-24-2215 |
0.788 |
|
| 2024 |
Rogers ZJ, Colombani T, Khan S, Bhatt K, Nukovic A, Zhou G, Woolston BM, Taylor CT, Gilkes DM, Slavov N, Bencherif SA. Controlling Pericellular Oxygen Tension in Cell Culture Reveals Distinct Breast Cancer Responses to Low Oxygen Tensions. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2402557. PMID 38874400 DOI: 10.1002/advs.202402557 |
0.632 |
|
| 2024 |
Oza HH, Gilkes DM. Multiplex Immunofluorescence Staining Protocol for the Dual Imaging of Hypoxia-Inducible Factors 1 and 2 on Formalin-Fixed Paraffin-Embedded Samples. Methods in Molecular Biology (Clifton, N.J.). 2755: 167-178. PMID 38319577 DOI: 10.1007/978-1-0716-3633-6_12 |
0.644 |
|
| 2024 |
Oza HH, Ng E, Gilkes DM. Staining Hypoxic Areas of Frozen and FFPE Tissue Sections with Hypoxyprobe™. Methods in Molecular Biology (Clifton, N.J.). 2755: 149-163. PMID 38319576 DOI: 10.1007/978-1-0716-3633-6_11 |
0.664 |
|
| 2024 |
Weinstein AG, Gilkes DM, Godet I. Mapping the Fate of Hypoxic Cells Using an Irreversible Fluorescent Switch. Methods in Molecular Biology (Clifton, N.J.). 2755: 49-61. PMID 38319568 DOI: 10.1007/978-1-0716-3633-6_3 |
0.829 |
|
| 2023 |
Rogers ZJ, Colombani T, Khan S, Bhatt K, Nukovic A, Zhou G, Woolston BM, Taylor CT, Gilkes DM, Slavov N, Bencherif SA. Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions. Biorxiv : the Preprint Server For Biology. PMID 37873449 DOI: 10.1101/2023.10.02.560369 |
0.616 |
|
| 2023 |
Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Retraction: Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis. Molecular Cancer Research : McR. 21: 1120. PMID 37779464 DOI: 10.1158/1541-7786.MCR-23-0654 |
0.861 |
|
| 2023 |
Deshpande A, Loth M, Sidiropoulos DN, Zhang S, Yuan L, Bell ATF, Zhu Q, Ho WJ, Santa-Maria C, Gilkes DM, Williams SR, Uytingco CR, Chew J, Hartnett A, Bent ZW, et al. Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces. Cell Systems. 14: 722. PMID 37591207 DOI: 10.1016/j.cels.2023.07.006 |
0.603 |
|
| 2023 |
Deshpande A, Loth M, Sidiropoulos DN, Zhang S, Yuan L, Bell ATF, Zhu Q, Ho WJ, Santa-Maria C, Gilkes DM, Williams SR, Uytingco CR, Chew J, Hartnett A, Bent ZW, et al. Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces. Cell Systems. 14: 285-301.e4. PMID 37080163 DOI: 10.1016/j.cels.2023.03.004 |
0.641 |
|
| 2023 |
Joe NS, Wang Y, Oza HH, Godet I, Milki N, Riggins GJ, Gilkes DM. Mebendazole Treatment Disrupts the Transcriptional Activity of Hypoxia-Inducible Factors 1 and 2 in Breast Cancer Cells. Cancers. 15. PMID 36831670 DOI: 10.3390/cancers15041330 |
0.861 |
|
| 2022 |
Joe NS, Godet I, Milki N, Ain NUI, Oza HH, Riggins GJ, Gilkes DM. Mebendazole prevents distant organ metastases in part by decreasing ITGβ4 expression and cancer stemness. Breast Cancer Research : Bcr. 24: 98. PMID 36578038 DOI: 10.1186/s13058-022-01591-3 |
0.853 |
|
| 2022 |
Weinstein AG, Godet I, Gilkes DM. The rise of viperin: the emerging role of viperin in cancer progression. The Journal of Clinical Investigation. 132. PMID 36519538 DOI: 10.1172/JCI165907 |
0.848 |
|
| 2022 |
Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, Tao J, Shatkin G, Lee SJ, Zhang Y, Boen A, ... ... Gilkes DM, et al. Extracellular fluid viscosity enhances cell migration and cancer dissemination. Nature. PMID 36323783 DOI: 10.1038/s41586-022-05394-6 |
0.831 |
|
| 2022 |
Bhatavdekar O, Godet I, Gilkes D, Sofou S. The Rate of Cisplatin Dosing Affects the Resistance and Metastatic Potential of Triple Negative Breast Cancer Cells, Independent of Hypoxia. Pharmaceutics. 14. PMID 36297617 DOI: 10.3390/pharmaceutics14102184 |
0.829 |
|
| 2022 |
Marin S, Godet I, Nidadavolu LS, Tian J, Dickinson LE, Walston JD, Gilkes DM, Abadir PM. Valsartan and sacubitril combination treatment enhances collagen production in older adult human skin cells. Experimental Gerontology. 111835. PMID 35598697 DOI: 10.1016/j.exger.2022.111835 |
0.765 |
|
| 2022 |
Godet I, Doctorman S, Wu F, Gilkes DM. Detection of Hypoxia in Cancer Models: Significance, Challenges, and Advances. Cells. 11. PMID 35203334 DOI: 10.3390/cells11040686 |
0.836 |
|
| 2021 |
Godet I, Mamo M, Thurnheer A, Rosen DM, Gilkes DM. Post-Hypoxic Cells Promote Metastatic Recurrence after Chemotherapy Treatment in TNBC. Cancers. 13. PMID 34771673 DOI: 10.3390/cancers13215509 |
0.863 |
|
| 2021 |
Rocha HL, Godet I, Kurtoglu F, Metzcar J, Konstantinopoulos K, Bhoyar S, Gilkes DM, Macklin P. A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling. Iscience. 24: 102935. PMID 34568781 DOI: 10.1016/j.isci.2021.102935 |
0.824 |
|
| 2021 |
Joe NS, Hodgdon C, Kraemer L, Redmond KJ, Stearns V, Gilkes DM. A common goal to CARE: Cancer Advocates, Researchers, and Clinicians Explore current treatments and clinical trials for breast cancer brain metastases. Npj Breast Cancer. 7: 121. PMID 34521857 DOI: 10.1038/s41523-021-00326-5 |
0.83 |
|
| 2021 |
Wang R, Godet I, Yang Y, Salman S, Lu H, Lyu Y, Zuo Q, Wang Y, Zhu Y, Chen C, He J, Gilkes DM, Semenza GL. Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33952697 DOI: 10.1073/pnas.2020490118 |
0.871 |
|
| 2020 |
DiGiacomo JW, Godet I, Trautmann-Rodriguez M, Gilkes DM. Extracellular matrix-bound FGF2 mediates estrogen receptor signaling and therapeutic response in breast cancer. Molecular Cancer Research : McR. PMID 33033110 DOI: 10.1158/1541-7786.MCR-20-0554 |
0.827 |
|
| 2020 |
Mamo M, Ye IC, DiGiacomo JW, Park JY, Downs B, Gilkes DM. Hypoxia alters the response to anti-EGFR therapy by regulating EGFR expression and downstream signaling in a DNA methylation-specific and HIF-dependent manner. Cancer Research. PMID 33023947 DOI: 10.1158/0008-5472.CAN-20-1232 |
0.847 |
|
| 2020 |
Wu PH, Gilkes DM, Phillip JM, Narkar A, Cheng TW, Marchand J, Lee MH, Li R, Wirtz D. Single-cell morphology encodes metastatic potential. Science Advances. 6: eaaw6938. PMID 32010778 DOI: 10.1126/Sciadv.Aaw6938 |
0.741 |
|
| 2019 |
Godet I, Shin YJ, Ju JA, Ye IC, Wang G, Gilkes DM. Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis. Nature Communications. 10: 4862. PMID 31649238 DOI: 10.1038/S41467-019-12412-1 |
0.831 |
|
| 2019 |
DiGiacomo JW, Gilkes DM. Therapeutic Strategies to Block the Hypoxic Response. Advances in Experimental Medicine and Biology. 1136: 141-157. PMID 31201722 DOI: 10.1007/978-3-030-12734-3_10 |
0.802 |
|
| 2019 |
Gilkes DM, Wirtz D. Solid Stress in Brain Tumors. Trends in Cancer. 5: 266-268. PMID 31174838 DOI: 10.1016/J.Trecan.2019.03.003 |
0.662 |
|
| 2019 |
Xiang L, Gilkes DM. The Contribution of the Immune System in Bone Metastasis Pathogenesis. International Journal of Molecular Sciences. 20. PMID 30823602 DOI: 10.3390/Ijms20040999 |
0.678 |
|
| 2019 |
Godet I, Shin YJ, Ju JA, Bhoyar S, Ye IC, Wang G, Sukumar S, Gilkes DM. Abstract 2649: A novel approach to fate-map hypoxic cells during tumor progression uncovers metastatic potency of post-hypoxic cells Cancer Research. 79: 2649-2649. DOI: 10.1158/1538-7445.Am2019-2649 |
0.845 |
|
| 2019 |
DiGiacomo JW, Godet I, Rodriguez MT, Ye IC, Gilkes DM. Abstract 1010: Extracellular matrix signaling modulates estrogen receptor activity in breast cancer Cancer Research. 79: 1010-1010. DOI: 10.1158/1538-7445.Am2019-1010 |
0.846 |
|
| 2019 |
Ju JA, Godet I, DiGiacomo JW, Gilkes DM. RhoB is regulated by hypoxia and modulates metastasis in breast cancer Cancer Reports. 3. DOI: 10.1002/CNR2.1164 |
0.847 |
|
| 2018 |
Bhoyar S, Godet I, DiGiacomo JW, Gilkes DM. A software tool for the quantification of metastatic colony growth dynamics and size distributions in vitro and in vivo. Plos One. 13: e0209591. PMID 30589908 DOI: 10.1371/Journal.Pone.0209591 |
0.784 |
|
| 2018 |
Ye IC, Fertig EJ, DiGiacomo JW, Considine M, Godet I, Gilkes DM. Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-regulated Genes. Molecular Cancer Research : McR. PMID 30037853 DOI: 10.1158/1541-7786.Mcr-18-0345 |
0.844 |
|
| 2018 |
DiGiacomo JW, Gilkes DM. Tumor Hypoxia As an Enhancer of Inflammation-Mediated Metastasis: Emerging Therapeutic Strategies. Targeted Oncology. PMID 29423593 DOI: 10.1007/S11523-018-0555-4 |
0.829 |
|
| 2018 |
Belcher DA, Ju JA, Baek JH, Yalamanoglu A, Buehler PW, Gilkes DM, Palmer AF. The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study. Plos One. 13: e0191275. PMID 29414985 DOI: 10.1371/Journal.Pone.0191275 |
0.696 |
|
| 2018 |
Ju JA, Gilkes DM. RhoB: Team Oncogene or Team Tumor Suppressor? Genes. 9. PMID 29385717 DOI: 10.3390/Genes9020067 |
0.695 |
|
| 2018 |
Wu P, Gilkes DM, Wirtz D. The Biophysics of 3D Cell Migration Annual Review of Biophysics. 47: 549-567. DOI: 10.1146/Annurev-Biophys-070816-033854 |
0.664 |
|
| 2017 |
Phillip JM, Wu PH, Gilkes DM, Williams W, McGovern S, Daya J, Chen J, Aifuwa I, Lee JSH, Fan R, Walston J, Wirtz D. Biophysical and biomolecular determination of cellular age in humans. Nature Biomedical Engineering. 1. PMID 31372309 DOI: 10.1038/S41551-017-0093 |
0.639 |
|
| 2017 |
Jun JC, Rathore A, Younas H, Gilkes D, Polotsky VY. Hypoxia-Inducible Factors and Cancer. Current Sleep Medicine Reports. 3: 1-10. PMID 28944164 DOI: 10.1007/s40675-017-0062-7 |
0.744 |
|
| 2017 |
Godet I, Gilkes DM. BRCA1 and BRCA2 mutations and treatment strategies for breast cancer. Integrative Cancer Science and Therapeutics. 4. PMID 28706734 DOI: 10.15761/Icst.1000228 |
0.837 |
|
| 2017 |
Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D. Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration. Nature Communications. 8: 15584. PMID 28548090 DOI: 10.1038/Ncomms15584 |
0.695 |
|
| 2017 |
Ju JA, Godet I, Ye IC, Byun J, Jayatilaka H, Lee SJ, Xiang L, Samanta D, Lee MH, Wu PH, Wirtz D, Semenza GL, Gilkes DM. Hypoxia Selectively Enhances Integrin Receptor Expression to Promote Metastasis. Molecular Cancer Research : McR. PMID 28213554 DOI: 10.1158/1541-7786.Mcr-16-0338 |
0.857 |
|
| 2017 |
Gilkes DM, Wirtz D. Tumour mechanopathology: Cutting the stress out Nature Biomedical Engineering. 1. DOI: 10.1038/S41551-016-0012 |
0.604 |
|
| 2016 |
Gilkes DM. Implications of Hypoxia in Breast Cancer Metastasis to Bone. International Journal of Molecular Sciences. 17. PMID 27706047 DOI: 10.3390/Ijms17101669 |
0.786 |
|
| 2016 |
Samanta D, Park Y, Andrabi SA, Shelton LM, Gilkes DM, Semenza GL. PHGDH Expression is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance and Lung Metastasis. Cancer Research. PMID 27280394 DOI: 10.1158/0008-5472.Can-16-0530 |
0.836 |
|
| 2015 |
Jimenez Valencia AM, Wu PH, Yogurtcu ON, Rao P, DiGiacomo J, Godet I, He L, Lee MH, Gilkes D, Sun SX, Wirtz D. Collective cancer cell invasion induced by coordinated contractile stresses. Oncotarget. PMID 26528856 DOI: 10.18632/Oncotarget.5874 |
0.797 |
|
| 2015 |
Zhang H, Lu H, Xiang L, Bullen JW, Zhang C, Samanta D, Gilkes DM, He J, Semenza GL. HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26512116 DOI: 10.1073/Pnas.1520032112 |
0.806 |
|
| 2015 |
Lee MH, Wu PH, Gilkes D, Aifuwa I, Wirtz D. Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions. Oncotarget. PMID 26334095 DOI: 10.18632/Oncotarget.4728 |
0.711 |
|
| 2015 |
Xiang L, Gilkes DM, Hu H, Luo W, Bullen JW, Liang H, Semenza GL. HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells. Oncotarget. 6: 11768-78. PMID 26059435 DOI: 10.18632/Oncotarget.4190 |
0.834 |
|
| 2014 |
Xiang L, Gilkes DM, Hu H, Takano N, Luo W, Lu H, Bullen JW, Samanta D, Liang H, Semenza GL. Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype. Oncotarget. 5: 12509-27. PMID 25587023 DOI: 10.18632/Oncotarget.2997 |
0.866 |
|
| 2014 |
Samanta D, Gilkes DM, Chaturvedi P, Xiang L, Semenza GL. Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E5429-38. PMID 25453096 DOI: 10.1073/Pnas.1421438111 |
0.838 |
|
| 2014 |
Hu H, Takano N, Xiang L, Gilkes DM, Luo W, Semenza GL. Hypoxia-inducible factors enhance glutamate signaling in cancer cells. Oncotarget. 5: 8853-68. PMID 25326682 DOI: 10.18632/Oncotarget.2593 |
0.828 |
|
| 2014 |
Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL. Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 111: E3325-34. PMID 25071185 DOI: 10.1073/Pnas.1412840111 |
0.803 |
|
| 2014 |
Takano N, Sarfraz Y, Gilkes DM, Chaturvedi P, Xiang L, Suematsu M, Zagzag D, Semenza GL. Decreased expression of cystathionine β-synthase promotes glioma tumorigenesis. Molecular Cancer Research : McR. 12: 1398-406. PMID 24994751 DOI: 10.1158/1541-7786.Mcr-14-0184 |
0.761 |
|
| 2014 |
Wang T, Gilkes DM, Takano N, Xiang L, Luo W, Bishop CJ, Chaturvedi P, Green JJ, Semenza GL. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 111: E3234-42. PMID 24938788 DOI: 10.1073/Pnas.1410041111 |
0.875 |
|
| 2014 |
Gilkes DM, Semenza GL, Wirtz D. Hypoxia and the extracellular matrix: drivers of tumour metastasis. Nature Reviews. Cancer. 14: 430-9. PMID 24827502 DOI: 10.1038/Nrc3726 |
0.77 |
|
| 2014 |
Chaturvedi P, Gilkes DM, Takano N, Semenza GL. Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment. Proceedings of the National Academy of Sciences of the United States of America. 111: E2120-9. PMID 24799675 DOI: 10.1073/Pnas.1406655111 |
0.799 |
|
| 2014 |
Xiang L, Gilkes DM, Chaturvedi P, Luo W, Hu H, Takano N, Liang H, Semenza GL. Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer. Journal of Molecular Medicine (Berlin, Germany). 92: 151-64. PMID 24248265 DOI: 10.1007/S00109-013-1102-5 |
0.874 |
|
| 2013 |
Gilkes DM, Semenza GL. Role of hypoxia-inducible factors in breast cancer metastasis. Future Oncology (London, England). 9: 1623-36. PMID 24156323 DOI: 10.2217/Fon.13.92 |
0.849 |
|
| 2013 |
Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL. Sirtuin-7 inhibits the activity of hypoxia-inducible factors. The Journal of Biological Chemistry. 288: 20768-75. PMID 23750001 DOI: 10.1074/Jbc.M113.476903 |
0.799 |
|
| 2013 |
Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL. Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Research. 73: 3285-96. PMID 23539444 DOI: 10.1158/0008-5472.Can-12-3963 |
0.868 |
|
| 2013 |
Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL. A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication Science Signaling. 6. PMID 23405012 DOI: 10.1126/Scisignal.2003417 |
0.789 |
|
| 2013 |
Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Molecular Cancer Research : McR. 11: 456-66. PMID 23378577 DOI: 10.1158/1541-7786.Mcr-12-0629 |
0.866 |
|
| 2013 |
Chaturvedi P, Gilkes DM, Wong CC, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. The Journal of Clinical Investigation. 123: 189-205. PMID 23318994 DOI: 10.1172/Jci64993 |
0.86 |
|
| 2013 |
Chaturvedi P, Gilkes DM, Wong CCL, Kshitiz, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Erratum: Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis (Journal of Clinical Investigation (2013) 123: 1 (189-205) DOI: 10.1172/JCI64993) Journal of Clinical Investigation. 123. DOI: 10.1172/Jci69244 |
0.85 |
|
| 2013 |
Gilkes DM, Chaturvedi P, Wong C, Bajpai S, Wei H, Hubbi M, Wirtz D, Semenza G. Abstract A3: Collagen hydroxylases are essential for breast cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A3 |
0.866 |
|
| 2013 |
Chaturvedi P, Gilkes D, Semenza G. Abstract 505: Hypoxia inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. Cancer Research. 73: 505-505. DOI: 10.1158/1538-7445.Am2013-505 |
0.839 |
|
| 2013 |
Gilkes DM, Chaturvedi P, Bajpai S, Hubbi M, Wirtz D, Semenza G. Abstract 3937: Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Research. 73: 3937-3937. DOI: 10.1158/1538-7445.Am2013-3937 |
0.865 |
|
| 2012 |
Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL. Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. Journal of Molecular Medicine (Berlin, Germany). 90: 803-15. PMID 22231744 DOI: 10.1007/S00109-011-0855-Y |
0.865 |
|
| 2012 |
Hubbi ME, Gilkes DM, Baek JH, Semenza GL. Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1. The Journal of Biological Chemistry. 287: 6139-49. PMID 22219185 DOI: 10.1074/Jbc.M111.278630 |
0.807 |
|
| 2012 |
Li X, Gilkes D, Li B, Cheng Q, Pernazza D, Lawrence H, Lawrence N, Chen J. Abnormal MDMX degradation in tumor cells due to ARF deficiency. Oncogene. 31: 3721-32. PMID 22120712 DOI: 10.1038/Onc.2011.534 |
0.715 |
|
| 2011 |
Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 16369-74. PMID 21911388 DOI: 10.1073/Pnas.1113483108 |
0.857 |
|
| 2011 |
Wong CCL, Gilkes D, Zhang H, Chen J, Chaturvedi P, Fraley S, Semenza GL. Abstract 1521: Hypoxia inducible factor is an important regulator of metastatic niche formation Cancer Research. 71: 1521-1521. DOI: 10.1158/1538-7445.Am2011-1521 |
0.843 |
|
| 2008 |
Gilkes DM, Pan Y, Coppola D, Yeatman T, Reuther GW, Chen J. Regulation of MDMX expression by mitogenic signaling. Molecular and Cellular Biology. 28: 1999-2010. PMID 18172009 DOI: 10.1128/Mcb.01633-07 |
0.757 |
|
| 2007 |
Hu B, Gilkes DM, Chen J. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX. Cancer Research. 67: 8810-7. PMID 17875722 DOI: 10.1158/0008-5472.Can-07-1140 |
0.712 |
|
| 2007 |
Gilkes DM, Chen J. Distinct roles of MDMX in the regulation of p53 response to ribosomal stress. Cell Cycle (Georgetown, Tex.). 6: 151-5. PMID 17327702 DOI: 10.4161/Cc.6.2.3719 |
0.693 |
|
| 2006 |
Gilkes DM, Chen L, Chen J. MDMX regulation of p53 response to ribosomal stress. The Embo Journal. 25: 5614-25. PMID 17110929 DOI: 10.1038/Sj.Emboj.7601424 |
0.704 |
|
| 2006 |
Hu B, Gilkes DM, Farooqi B, Sebti SM, Chen J. MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin. The Journal of Biological Chemistry. 281: 33030-5. PMID 16905541 DOI: 10.1074/Jbc.C600147200 |
0.694 |
|
| 2006 |
LeBron C, Chen L, Gilkes DM, Chen J. Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. The Embo Journal. 25: 1196-206. PMID 16511560 DOI: 10.1038/Sj.Emboj.7601032 |
0.763 |
|
| 2005 |
Nefedova Y, Cheng P, Gilkes D, Blaskovich M, Beg AA, Sebti SM, Gabrilovich DI. Activation of dendritic cells via inhibition of Jak2/STAT3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 4338-46. PMID 16177074 DOI: 10.4049/Jimmunol.175.7.4338 |
0.662 |
|
| 2005 |
Chen L, Gilkes DM, Pan Y, Lane WS, Chen J. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage. The Embo Journal. 24: 3411-22. PMID 16163388 DOI: 10.1038/Sj.Emboj.7600812 |
0.699 |
|
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