Howard A. Rockman - Publications

Cell Biology Duke University, Durham, NC 
Cell Biology, Genetics

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Abraham DM, Lee TE, Watson LJ, Mao L, Chandok GS, Wang HG, Frangakis S, Pitt GS, Shah SH, Wolf MJ, Rockman HA. The two-pore-domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction. The Journal of Clinical Investigation. PMID 30153110 DOI: 10.1172/Jci95945  0.36
2015 Xu W, Barrientos T, Mao L, Rockman HA, Sauve AA, Andrews NC. Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart. Cell Reports. 13: 533-45. PMID 26456827 DOI: 10.1016/J.Celrep.2015.09.023  0.36
2015 Wisler JW, Harris EM, Raisch M, Mao L, Kim J, Rockman HA, Lefkowitz RJ. The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1516-27. PMID 26371162 DOI: 10.1152/Ajpheart.00291.2015  0.36
2015 Pironti G, Strachan RT, Abraham D, Mon-Wei Yu S, Chen M, Chen W, Hanada K, Mao L, Watson LJ, Rockman HA. Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors. Circulation. 131: 2120-30. PMID 25995315 DOI: 10.1161/Circulationaha.115.015687  0.36
2014 Rockman HA. Happy birthday JCI. The Journal of Clinical Investigation. 124: 4135-6. PMID 25271720 DOI: 10.1172/Jci78708  0.36
2014 Tang W, Strachan RT, Lefkowitz RJ, Rockman HA. Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch. The Journal of Biological Chemistry. 289: 28271-83. PMID 25170081 DOI: 10.1074/Jbc.M114.585067  0.36
2014 Lee TE, Yu L, Wolf MJ, Rockman HA. Galactokinase is a novel modifier of calcineurin-induced cardiomyopathy in Drosophila. Genetics. 198: 591-603. PMID 25081566 DOI: 10.1534/Genetics.114.166777  0.36
2014 Ashton JR, Befera N, Clark D, Qi Y, Mao L, Rockman HA, Johnson GA, Badea CT. Anatomical and functional imaging of myocardial infarction in mice using micro-CT and eXIA 160 contrast agent. Contrast Media & Molecular Imaging. 9: 161-8. PMID 24523061 DOI: 10.1002/Cmmi.1557  0.36
2014 Rockman HA. Waste not, want not. The Journal of Clinical Investigation. 124: 463. PMID 24487638 DOI: 10.1172/Jci75011  0.36
2014 Kim IM, Wang Y, Park KM, Tang Y, Teoh JP, Vinson J, Traynham CJ, Pironti G, Mao L, Su H, Johnson JA, Koch WJ, Rockman HA. β-arrestin1-biased β1-adrenergic receptor signaling regulates microRNA processing. Circulation Research. 114: 833-44. PMID 24334028 DOI: 10.1161/Circresaha.114.302766  0.36
2014 Santacruz L, Hernandez A, Nienaber J, Mishra R, Pinilla M, Burchette J, Mao L, Rockman HA, Jacobs DO. Normal cardiac function in mice with supraphysiological cardiac creatine levels. American Journal of Physiology. Heart and Circulatory Physiology. 306: H373-81. PMID 24271489 DOI: 10.1152/Ajpheart.00411.2013  0.36
2013 Tang H, Xiao K, Mao L, Rockman HA, Marchuk DA. Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 54: 101-11. PMID 23085512 DOI: 10.1016/J.Yjmcc.2012.10.004  0.36
2013 Rockman HA. Tempus fugit Journal of Clinical Investigation. 123: 935-936. DOI: 10.1172/JCI69370  0.36
2012 Kim KS, Abraham D, Williams B, Violin JD, Mao L, Rockman HA. β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1001-10. PMID 22886417 DOI: 10.1152/Ajpheart.00475.2012  0.36
2012 Lee CL, Moding EJ, Cuneo KC, Li Y, Sullivan JM, Mao L, Washington I, Jeffords LB, Rodrigues RC, Ma Y, Das S, Kontos CD, Kim Y, Rockman HA, Kirsch DG. p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice. Science Signaling. 5: ra52. PMID 22827996 DOI: 10.1126/Scisignal.2002918  0.36
2012 Neill US, Rockman HA. A conversation with Robert Lefkowitz, Joseph Goldstein, and Michael Brown Journal of Clinical Investigation. 122: 1586-1587. PMID 22690398 DOI: 10.1172/Jci64244  0.36
2012 Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/Res.0B013E3182582523  0.36
2012 Rockman HA. Great expectations. The Journal of Clinical Investigation. 122: 1133. PMID 22466653 DOI: 10.1172/JCI63462  0.36
2012 Casad ME, Yu L, Daniels JP, Wolf MJ, Rockman HA. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Molecular Genetics and Genomics : Mgg. 287: 351-60. PMID 22398840 DOI: 10.1007/S00438-012-0684-X  0.36
2012 Rockman HA. Tradition, tradition. The Journal of Clinical Investigation. 122: 785-6. PMID 22378046 DOI: 10.1172/Jci63105  0.36
2012 Caplan AL, Rockman HA, Turka LA. Editorial position on publishing articles on human organ transplantation. The Journal of Clinical Investigation. 122: 2. PMID 22214852 DOI: 10.1172/Jci61904  0.36
2012 Rockman HA. Clinical medicine Journal of Clinical Investigation. 122: 4303. DOI: 10.1172/JCI67619  0.36
2011 Shenoy SK, Rockman HA. Cardiovascular biology: heart fails without pump partner. Nature. 477: 546-7. PMID 21956327 DOI: 10.1038/477546A  0.36
2011 Wolf MJ, Rockman HA. Drosophila, genetic screens, and cardiac function. Circulation Research. 109: 794-806. PMID 21921272 DOI: 10.1161/Circresaha.111.244897  0.36
2011 Casad ME, Abraham D, Kim IM, Frangakis S, Dong B, Lin N, Wolf MJ, Rockman HA. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Genetics. 189: 861-70. PMID 21890737 DOI: 10.1534/Genetics.111.131482  0.36
2011 Rockman HA, Lefkowitz RJ. Introduction to the series on novel aspects of cardiovascular G-protein-coupled receptor signaling. Circulation Research. 109: 202-4. PMID 21737815 DOI: 10.1161/Circresaha.110.231126  0.36
2011 Lin N, Badie N, Yu L, Abraham D, Cheng H, Bursac N, Rockman HA, Wolf MJ. A method to measure myocardial calcium handling in adult Drosophila. Circulation Research. 108: 1306-15. PMID 21493892 DOI: 10.1161/Circresaha.110.238105  0.36
2011 Grotegut CA, Feng L, Mao L, Heine RP, Murtha AP, Rockman HA. β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration. American Journal of Physiology. Endocrinology and Metabolism. 300: E468-77. PMID 21139074 DOI: 10.1152/Ajpendo.00390.2010  0.36
2011 Noor N, Patel CB, Rockman HA. Β-arrestin: a signaling molecule and potential therapeutic target for heart failure. Journal of Molecular and Cellular Cardiology. 51: 534-41. PMID 21074538 DOI: 10.1016/J.Yjmcc.2010.11.005  0.36
2010 Patel CB, Noor N, Rockman HA. Functional selectivity in adrenergic and angiotensin signaling systems. Molecular Pharmacology. 78: 983-92. PMID 20855464 DOI: 10.1124/Mol.110.067066  0.36
2010 Rakesh K, Yoo B, Kim IM, Salazar N, Kim KS, Rockman HA. beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. Science Signaling. 3: ra46. PMID 20530803 DOI: 10.1126/Scisignal.2000769  0.36
2010 Tilley DG, Nguyen AD, Rockman HA. Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor. Biochemical and Biophysical Research Communications. 396: 921-6. PMID 20460106 DOI: 10.1016/J.Bbrc.2010.05.023  0.36
2010 Kim BE, Turski ML, Nose Y, Casad M, Rockman HA, Thiele DJ. Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs. Cell Metabolism. 11: 353-63. PMID 20444417 DOI: 10.1016/J.Cmet.2010.04.003  0.36
2010 Mangmool S, Shukla AK, Rockman HA. beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation. The Journal of Cell Biology. 189: 573-87. PMID 20421423 DOI: 10.1083/Jcb.200911047  0.36
2010 Bucholz E, Ghaghada K, Qi Y, Mukundan S, Rockman HA, Johnson GA. Cardiovascular phenotyping of the mouse heart using a 4D radial acquisition and liposomal Gd-DTPA-BMA. Magnetic Resonance in Medicine. 63: 979-87. PMID 20373399 DOI: 10.1002/Mrm.22259  0.36
2010 Kim IM, Wolf MJ, Rockman HA. Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. Circulation Research. 106: 1233-43. PMID 20203305 DOI: 10.1161/Circresaha.109.213785  0.36
2010 Rockman HA, VanHook AM. Science signaling podcast: 8 June 2010 Science Signaling. 3. DOI: 10.1126/scisignal.3125pc12  0.36
2009 Seth M, Zhang ZS, Mao L, Graham V, Burch J, Stiber J, Tsiokas L, Winn M, Abramowitz J, Rockman HA, Birnbaumer L, Rosenberg P. TRPC1 channels are critical for hypertrophic signaling in the heart. Circulation Research. 105: 1023-30. PMID 19797170 DOI: 10.1161/Circresaha.109.206581  0.36
2009 Wheeler FC, Tang H, Marks OA, Hadnott TN, Chu PL, Mao L, Rockman HA, Marchuk DA. Tnni3k modifies disease progression in murine models of cardiomyopathy. Plos Genetics. 5: e1000647. PMID 19763165 DOI: 10.1371/Journal.Pgen.1000647  0.36
2009 Yoo B, Lemaire A, Mangmool S, Wolf MJ, Curcio A, Mao L, Rockman HA. Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1377-86. PMID 19633206 DOI: 10.1152/Ajpheart.00504.2009  0.36
2009 Pandya K, Porter K, Rockman HA, Smithies O. Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain. European Journal of Heart Failure. 11: 648-52. PMID 19553396 DOI: 10.1093/Eurjhf/Hfp073  0.36
2009 Tilley DG, Kim IM, Patel PA, Violin JD, Rockman HA. beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling. The Journal of Biological Chemistry. 284: 20375-86. PMID 19509284 DOI: 10.1074/Jbc.M109.005793  0.36
2009 Fernandez L, Marchuk DA, Moran JL, Beier DR, Rockman HA. An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 296-304. PMID 19387734 DOI: 10.1007/S00335-009-9184-7  0.36
2009 Lima B, Lam GK, Xie L, Diesen DL, Villamizar N, Nienaber J, Messina E, Bowles D, Kontos CD, Hare JM, Stamler JS, Rockman HA. Endogenous S-nitrosothiols protect against myocardial injury. Proceedings of the National Academy of Sciences of the United States of America. 106: 6297-302. PMID 19325130 DOI: 10.1073/Pnas.0901043106  0.36
2009 Mehra MR, Rockman HA, Greenberg BH. Highlights of the 2008 Scientific Sessions of the Heart Failure Society of America. Toronto, Ontario, Canada, September 20-23, 2008. Journal of the American College of Cardiology. 53: 514-22. PMID 19195609 DOI: 10.1016/J.Jacc.2008.11.003  0.36
2009 Acehan D, Khuchua Z, Houtkooper RH, Malhotra A, Kaufman J, Vaz FM, Ren M, Rockman HA, Stokes DL, Schlame M. Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria. Mitochondrion. 9: 86-95. PMID 19114128 DOI: 10.1016/J.Mito.2008.12.001  0.36
2009 Patel PA, Tilley DG, Rockman HA. Physiologic and cardiac roles of beta-arrestins. Journal of Molecular and Cellular Cardiology. 46: 300-8. PMID 19103204 DOI: 10.1016/J.Yjmcc.2008.11.015  0.36
2008 Wolf MJ, Rockman HA. Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discovery Today. Disease Models. 5: 117-123. PMID 19802348 DOI: 10.1016/J.Ddmod.2009.02.002  0.36
2008 Patel PA, Tilley DG, Rockman HA. Beta-arrestin-mediated signaling in the heart. Circulation Journal : Official Journal of the Japanese Circulation Society. 72: 1725-9. PMID 18838825 DOI: 10.1253/Circj.Cj-08-0734  0.36
2008 Kim IM, Tilley DG, Chen J, Salazar NC, Whalen EJ, Violin JD, Rockman HA. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14555-60. PMID 18787115 DOI: 10.1073/Pnas.0804745105  0.36
2008 Pandya K, Cowhig J, Brackhan J, Kim HS, Hagaman J, Rojas M, Carter CW, Mao L, Rockman HA, Maeda N, Smithies O. Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 13063-8. PMID 18755891 DOI: 10.1073/Pnas.0805120105  0.36
2008 Francois H, Makhanova N, Ruiz P, Ellison J, Mao L, Rockman HA, Coffman TM. A role for the thromboxane receptor in L-NAME hypertension. American Journal of Physiology. Renal Physiology. 295: F1096-102. PMID 18684890 DOI: 10.1152/Ajprenal.00369.2007  0.36
2008 Ream MA, Chandra R, Peavey M, Ray AM, Roffler-Tarlov S, Kim HG, Wetsel WC, Rockman HA, Chikaraishi DM. High oxygen prevents fetal lethality due to lack of catecholamines. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R942-53. PMID 18635452 DOI: 10.1152/Ajpregu.00860.2007  0.36
2008 Barki-Harrington L, Rockman HA. Beta-arrestins: multifunctional cellular mediators. Physiology (Bethesda, Md.). 23: 17-22. PMID 18268361 DOI: 10.1152/Physiol.00042.2007  0.36
2008 Mehra MR, Rockman HA, Greenberg BH. Highlights of the 2007 Scientific Meeting of the Heart Failure Society of America: Washington, DC, September 16-19, 2007. Journal of the American College of Cardiology. 51: 320-7. PMID 18206743 DOI: 10.1016/J.Jacc.2007.11.026  0.36
2008 Esposito G, Perrino C, Ozaki T, Takaoka H, Defer N, Petretta MP, De Angelis MC, Mao L, Hanoune J, Rockman HA, Chiariello M. Increased myocardial contractility and enhanced exercise function in transgenic mice overexpressing either adenylyl cyclase 5 or 8. Basic Research in Cardiology. 103: 22-30. PMID 18034275 DOI: 10.1007/S00395-007-0688-6  0.36
2008 Chen J, Rockman HA. Receptor signaling pathways in heart failure: Transgenic mouse models Acute Heart Failure. 89-111. DOI: 10.1007/978-1-84628-782-4_10  0.36
2007 Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. Plos One. 2: e1051. PMID 17940615 DOI: 10.1371/Journal.Pone.0001051  0.36
2007 Allikian MJ, Bhabha G, Dospoy P, Heydemann A, Ryder P, Earley JU, Wolf MJ, Rockman HA, McNally EM. Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. Human Molecular Genetics. 16: 2933-43. PMID 17855453 DOI: 10.1093/Hmg/Ddm254  0.36
2007 Salzler HR, Griffiths R, Ruiz P, Chi L, Frey C, Marchuk DA, Rockman HA, Le TH. Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus. Kidney International. 72: 1226-32. PMID 17851470 DOI: 10.1038/Sj.Ki.5002519  0.36
2007 Noma T, Lemaire A, Naga Prasad SV, Barki-Harrington L, Tilley DG, Chen J, Le Corvoisier P, Violin JD, Wei H, Lefkowitz RJ, Rockman HA. Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. The Journal of Clinical Investigation. 117: 2445-58. PMID 17786238 DOI: 10.1172/Jci31901  0.36
2007 Perrino C, Rockman HA. Reversal of cardiac remodeling by modulation of adrenergic receptors: a new frontier in heart failure. Current Opinion in Cardiology. 22: 443-9. PMID 17762546 DOI: 10.1097/Hco.0B013E3282294D72  0.36
2007 Badea CT, Hedlund LW, Mackel JF, Mao L, Rockman HA, Johnson GA. Cardiac micro-computed tomography for morphological and functional phenotyping of muscle LIM protein null mice. Molecular Imaging. 6: 261-8. PMID 17711781 DOI: 10.2310/7290.2007.00022  0.36
2007 Whalen EJ, Foster MW, Matsumoto A, Ozawa K, Violin JD, Que LG, Nelson CD, Benhar M, Keys JR, Rockman HA, Koch WJ, Daaka Y, Lefkowitz RJ, Stamler JS. Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell. 129: 511-22. PMID 17482545 DOI: 10.1016/J.Cell.2007.02.046  0.36
2007 Salazar NC, Chen J, Rockman HA. Cardiac GPCRs: GPCR signaling in healthy and failing hearts. Biochimica Et Biophysica Acta. 1768: 1006-18. PMID 17376402 DOI: 10.1016/J.Bbamem.2007.02.010  0.36
2007 Donahue MP, Marchuk DA, Rockman HA. Reply Journal of the American College of Cardiology. 49: 1106-1107. DOI: 10.1016/J.Jacc.2006.12.019  0.36
2006 Rajagopal K, Whalen EJ, Violin JD, Stiber JA, Rosenberg PB, Premont RT, Coffman TM, Rockman HA, Lefkowitz RJ. Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 16284-9. PMID 17060617 DOI: 10.1073/Pnas.0607583103  0.36
2006 Donahue MP, Marchuk DA, Rockman HA. Redefining heart failure: the utility of genomics. Journal of the American College of Cardiology. 48: 1289-98. PMID 17010784 DOI: 10.1016/J.Jacc.2006.05.062  0.36
2006 Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. The Journal of Clinical Investigation. 116: 2218-25. PMID 16878172 DOI: 10.1172/Jci16980  0.36
2006 Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, et al. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research. 99: 442-50. PMID 16857962 DOI: 10.1161/01.Res.0000237390.92932.37  0.36
2006 Perrino C, Rockman HA, Chiariello M. Targeted inhibition of phosphoinositide 3-kinase activity as a novel strategy to normalize beta-adrenergic receptor function in heart failure. Vascular Pharmacology. 45: 77-85. PMID 16807128 DOI: 10.1016/J.Vph.2006.01.018  0.36
2006 Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. The Journal of Clinical Investigation. 116: 1547-60. PMID 16741575 DOI: 10.1172/Jci25397  0.36
2006 Tilley DG, Rockman HA. Role of beta-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment. Expert Review of Cardiovascular Therapy. 4: 417-32. PMID 16716102 DOI: 10.1586/14779072.4.3.417  0.36
2006 Curcio A, Noma T, Naga Prasad SV, Wolf MJ, Lemaire A, Perrino C, Mao L, Rockman HA. Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1754-60. PMID 16699071 DOI: 10.1152/Ajpheart.01199.2005  0.36
2006 Tachibana H, Perrino C, Takaoka H, Davis RJ, Naga Prasad SV, Rockman HA. JNK1 is required to preserve cardiac function in the early response to pressure overload. Biochemical and Biophysical Research Communications. 343: 1060-6. PMID 16579967 DOI: 10.1016/J.Bbrc.2006.03.065  0.36
2006 Perrino C, Rockman HA. GATA4 and the two sides of gene expression reprogramming. Circulation Research. 98: 715-6. PMID 16574910 DOI: 10.1161/01.Res.0000217593.07196.Af  0.36
2006 Volovyk ZM, Wolf MJ, Prasad SV, Rockman HA. Agonist-stimulated beta-adrenergic receptor internalization requires dynamic cytoskeletal actin turnover. The Journal of Biological Chemistry. 281: 9773-80. PMID 16461348 DOI: 10.1074/Jbc.M511435200  0.36
2006 Wolf MJ, Amrein H, Izatt JA, Choma MA, Reedy MC, Rockman HA. Drosophila as a model for the identification of genes causing adult human heart disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 1394-9. PMID 16432241 DOI: 10.1073/Pnas.0507359103  0.36
2005 Perrino C, Esposito G, Rockman HA. Defects in cardiomyocyte function: Role of beta-adrenergic receptor dysfunction Panminerva Medica. 47: 143-155. PMID 16462723  0.36
2005 Rajagopal K, Lefkowitz RJ, Rockman HA. When 7 transmembrane receptors are not G protein-coupled receptors. The Journal of Clinical Investigation. 115: 2971-4. PMID 16276410 DOI: 10.1172/Jci26950  0.36
2005 Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS, Rockman HA, Fitzgerald GA, Koller BH, Coffman TM. Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metabolism. 2: 201-7. PMID 16154102 DOI: 10.1016/J.Cmet.2005.08.005  0.36
2005 Chen Z, Foster MW, Zhang J, Mao L, Rockman HA, Kawamoto T, Kitagawa K, Nakayama KI, Hess DT, Stamler JS. An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proceedings of the National Academy of Sciences of the United States of America. 102: 12159-64. PMID 16103363 DOI: 10.1073/Pnas.0503723102  0.36
2005 Naga Prasad SV, Jayatilleke A, Madamanchi A, Rockman HA. Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis. Nature Cell Biology. 7: 785-96. PMID 16094730 DOI: 10.1038/Ncb1278  0.36
2005 Wheeler FC, Fernandez L, Carlson KM, Wolf MJ, Rockman HA, Marchuk DA. QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 414-23. PMID 16075368 DOI: 10.1007/S00335-005-2468-7  0.36
2005 Wolf MJ, Tachibana H, Rockman HA. Methods for the detection of altered beta-adrenergic receptor signaling pathways in hypertrophied hearts. Methods in Molecular Medicine. 112: 353-62. PMID 16010029 DOI: 10.1385/1-59259-879-X:353  0.36
2005 Perrino C, Naga Prasad SV, Patel M, Wolf MJ, Rockman HA. Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression. Journal of the American College of Cardiology. 45: 1862-70. PMID 15936620 DOI: 10.1016/J.Jacc.2005.02.062  0.36
2005 Perrino C, Naga Prasad SV, Schroder JN, Hata JA, Milano C, Rockman HA. Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex. Circulation. 111: 2579-87. PMID 15897344 DOI: 10.1161/Circulationaha.104.508796  0.36
2005 Tachibana H, Naga Prasad SV, Lefkowitz RJ, Koch WJ, Rockman HA. Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure. Circulation. 111: 591-7. PMID 15668342 DOI: 10.1161/01.Cir.0000142291.70954.Df  0.36
2005 van den Bosch BJ, van den Burg CM, Schoonderwoerd K, Lindsey PJ, Scholte HR, de Coo RF, van Rooij E, Rockman HA, Doevendans PA, Smeets HJ. Regional absence of mitochondria causing energy depletion in the myocardium of muscle LIM protein knockout mice. Cardiovascular Research. 65: 411-8. PMID 15639480 DOI: 10.1016/J.Cardiores.2004.10.025  0.36
2005 Nassar R, Malouf NN, Mao L, Rockman HA, Oakeley AE, Frye JR, Herlong JR, Sanders SP, Anderson PA. cTnT1, a cardiac troponin T isoform, decreases myofilament tension and affects the left ventricular pressure waveform. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1147-56. PMID 15513965 DOI: 10.1152/Ajpheart.00140.2004  0.36
2005 Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. The Journal of Biological Chemistry. 280: 669-76. PMID 15492008 DOI: 10.1074/Jbc.M406690200  0.36
2005 Skavdahl M, Steenbergen C, Clark J, Myers P, Demianenko T, Mao L, Rockman HA, Korach KS, Murphy E. Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 288: H469-76. PMID 15374829 DOI: 10.1152/Ajpheart.00723.2004  0.36
2005 Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS, Rockman HA, FitzGerald GA, Koller BH, Coffman TM. NSAIDs and cardiovascular risk - Reply [2] Cell Metabolism. 2: 339-340. DOI: 10.1016/j.cmet.2005.11.009  0.36
2004 Kedar V, McDonough H, Arya R, Li HH, Rockman HA, Patterson C. Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I. Proceedings of the National Academy of Sciences of the United States of America. 101: 18135-40. PMID 15601779 DOI: 10.1073/Pnas.0404341102  0.36
2004 Barki-Harrington L, Perrino C, Rockman HA. Network integration of the adrenergic system in cardiac hypertrophy. Cardiovascular Research. 63: 391-402. PMID 15276464 DOI: 10.1016/J.Cardiores.2004.03.011  0.36
2004 Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC. Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circulation Research. 95: 506-14. PMID 15256482 DOI: 10.1161/01.Res.0000139436.89654.C8  0.36
2004 Tong H, Rockman HA, Koch WJ, Steenbergen C, Murphy E. G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning. Circulation Research. 94: 1133-41. PMID 15031261 DOI: 10.1161/01.Res.0000126048.32383.6B  0.36
2004 Caron KM, James LR, Kim HS, Knowles J, Uhlir R, Mao L, Hagaman JR, Cascio W, Rockman H, Smithies O. Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proceedings of the National Academy of Sciences of the United States of America. 101: 3106-11. PMID 14978280 DOI: 10.1073/Pnas.0307333101  0.36
2004 Francois H, Athirakul K, Mao L, Rockman H, Coffman TM. Role for Thromboxane Receptors in Angiotensin-II-Induced Hypertension Hypertension. 43: 364-369. PMID 14718360 DOI: 10.1161/01.Hyp.0000112225.27560.24  0.36
2004 Lemaire A, Rockman HA. The role of G-protein-coupled receptors in heart failure Drug Discovery Today: Disease Mechanisms. 1: 37-43. DOI: 10.1016/J.Ddmec.2004.08.013  0.36
2003 Nienaber JJ, Tachibana H, Naga Prasad SV, Esposito G, Wu D, Mao L, Rockman HA. Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure. The Journal of Clinical Investigation. 112: 1067-79. PMID 14523044 DOI: 10.1172/Jci18213  0.36
2003 Le Corvoisier P, Park HY, Carlson KM, Marchuk DA, Rockman HA. Multiple quantitative trait loci modify the heart failure phenotype in murine cardiomyopathy. Human Molecular Genetics. 12: 3097-107. PMID 14519689 DOI: 10.1093/Hmg/Ddg333  0.36
2003 Barki-Harrington L, Luttrell LM, Rockman HA. Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation. 108: 1611-8. PMID 12963634 DOI: 10.1161/01.Cir.0000092166.30360.78  0.36
2003 Keys JR, Greene EA, Cooper CJ, Naga Prasad SV, Rockman HA, Koch WJ. Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2201-11. PMID 12869383 DOI: 10.1152/Ajpheart.00112.2003  0.36
2003 Blaxall BC, Spang R, Rockman HA, Koch WJ. Differential myocardial gene expression in the development and rescue of murine heart failure. Physiological Genomics. 15: 105-14. PMID 12865503 DOI: 10.1152/Physiolgenomics.00087.2003  0.36
2003 Naga Prasad SV, Perrino C, Rockman HA. Role of phosphoinositide 3-kinase in cardiac function and heart failure. Trends in Cardiovascular Medicine. 13: 206-12. PMID 12837584 DOI: 10.1016/S1050-1738(03)00080-X  0.36
2003 Rapacciuolo A, Suvarna S, Barki-Harrington L, Luttrell LM, Cong M, Lefkowitz RJ, Rockman HA. Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. The Journal of Biological Chemistry. 278: 35403-11. PMID 12821660 DOI: 10.1074/Jbc.M305675200  0.36
2003 Le Corvoisier P, Park HY, Rockman HA. Modifier genes and heart failure Minerva Cardioangiologica. 51: 107-120. PMID 12783067  0.36
2003 Most P, Remppis A, Pleger ST, Löffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H, Karczewski P, Mao L, Rockman HA, Duncan SJ, Katus HA, et al. Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. The Journal of Biological Chemistry. 278: 33809-17. PMID 12777394 DOI: 10.1074/Jbc.M301788200  0.36
2003 Le Corvoisier P, Park HY, Carlson KM, Donahue MP, Marchuk DA, Rockman HA. Impact of genetic polymorphisms on heart failure prognosis. Archives Des Maladies Du Coeur Et Des Vaisseaux. 96: 197-206. PMID 12722550  0.36
2003 Colomer JM, Mao L, Rockman HA, Means AR. Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo. Molecular Endocrinology (Baltimore, Md.). 17: 183-92. PMID 12554746 DOI: 10.1210/Me.2002-0350  0.36
2003 Barki-Harrington L, Rockman HA. Sensing heart stress. Nature Medicine. 9: 19-20. PMID 12514714 DOI: 10.1038/Nm0103-19  0.36
2002 Naga Prasad SV, Nienaber J, Rockman HA. G-protein-coupled receptor function in heart failure Cold Spring Harbor Symposia On Quantitative Biology. 67: 439-444. PMID 12858569 DOI: 10.1101/Sqb.2002.67.439  0.36
2002 Esposito G, Rapacciuolo A, Naga Prasad SV, Rockman HA. Cardiac hypertrophy: role of G protein-coupled receptors. Journal of Cardiac Failure. 8: S409-14. PMID 12555153 DOI: 10.1054/Jcaf.2002.129283  0.36
2002 Naga Prasad SV, Laporte SA, Chamberlain D, Caron MG, Barak L, Rockman HA. Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. The Journal of Cell Biology. 158: 563-75. PMID 12163475 DOI: 10.1083/Jcb.200202113  0.36
2002 Feldman DS, Zamah AM, Pierce KL, Miller WE, Kelly F, Rapacciuolo A, Rockman HA, Koch WJ, Luttrell LM. Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. The Journal of Biological Chemistry. 277: 28631-40. PMID 12036966 DOI: 10.1074/Jbc.M204753200  0.36
2002 Takaoka H, Esposito G, Mao L, Suga H, Rockman HA. Heart size-independent analysis of myocardial function in murine pressure overload hypertrophy American Journal of Physiology - Heart and Circulatory Physiology. 282. PMID 12003828 DOI: 10.1152/Ajpheart.00759.2001  0.36
2002 Suzuki M, Carlson KM, Marchuk DA, Rockman HA. Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy. Circulation. 105: 1824-9. PMID 11956126 DOI: 10.1161/01.Cir.0000014926.32463.89  0.36
2002 Eckhart AD, Ozaki T, Tevaearai H, Rockman HA, Koch WJ. Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates β-adrenergic receptor signaling and increases resting blood pressure Molecular Pharmacology. 61: 749-758. PMID 11901213 DOI: 10.1124/Mol.61.4.749  0.36
2002 Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 415: 206-12. PMID 11805844 DOI: 10.1038/415206A  0.36
2002 Esposito G, Rapacciuolo A, Naga Prasad SV, Takaoka H, Thomas SA, Koch WJ, Rockman HA. Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation. 105: 85-92. PMID 11772881 DOI: 10.1161/Hc0102.101365  0.36
2001 Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ, Rockman HA. Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice. Circulation. 104: 2485-91. PMID 11705829 DOI: 10.1161/Hc4501.098933  0.36
2001 Rapacciuolo A, Esposito G, Naga Prasad SV, Rockman HA. G protein-coupled receptor signalling in in vivo cardiac overload Acta Physiologica Scandinavica. 173: 51-57. PMID 11678726 DOI: 10.1046/J.1365-201X.2001.00884.X  0.36
2001 Naga Prasad SV, Nienaber J, Rockman HA. β-Adrenergic axis and heart disease Trends in Genetics. 17. PMID 11585676 DOI: 10.1016/S0168-9525(01)02487-8  0.36
2001 Rapacciuolo A, Esposito G, Caron K, Mao L, Thomas SA, Rockman HA. Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy. Journal of the American College of Cardiology. 38: 876-82. PMID 11527648 DOI: 10.1016/S0735-1097(01)01433-4  0.36
2001 Iaccarino G, Keys JR, Rapacciuolo A, Shotwell KF, Lefkowitz RJ, Rockman HA, Koch WJ. Regulation of myocardial betaARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing alpha1B-adrenergic receptors. Journal of the American College of Cardiology. 38: 534-40. PMID 11499749 DOI: 10.1016/S0735-1097(01)01396-1  0.36
2001 Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quinones LE, Santana LF. Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. The Journal of Biological Chemistry. 276: 28197-203. PMID 11369778 DOI: 10.1074/Jbc.M102548200  0.36
2001 Harding VB, Jones LR, Lefkowitz RJ, Koch WJ, Rockman HA. Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proceedings of the National Academy of Sciences of the United States of America. 98: 5809-14. PMID 11331748 DOI: 10.1073/Pnas.091102398  0.36
2001 Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of Clinical Investigation. 107: 975-84. PMID 11306601 DOI: 10.1172/Jci11273  0.36
2001 Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1: A role in receptor sequestration Journal of Biological Chemistry. 276: 18953-18959. PMID 11259422 DOI: 10.1074/Jbc.M102376200  0.36
2001 Esposito G, Naga Prasad SV, Rapacciuolo A, Mao L, Koch WJ, Rockman HA. Cardiac overexpression of a Gq inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activity in in vivo pressure overload Circulation. 103: 1453-1458. PMID 11245652 DOI: 10.1161/01.Cir.103.10.1453  0.36
2000 Manning BS, Shotwell K, Mao L, Rockman HA, Koch WJ. Physiological induction of a β-adrenergic receptor kinase inhibitor transgene preserves β-adrenergic responsiveness in pressure-overload cardiac hypertrophy Circulation. 102: 2751-2757. PMID 11094043 DOI: 10.1161/01.Cir.102.22.2751  0.36
2000 Esposito G, Santana LF, Dilly K, Cruz JD, Mao L, Lederer WJ, Rockman HA. Cellular and functional defects in a mouse model of heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3101-12. PMID 11087268 DOI: 10.1152/Ajpheart.2000.279.6.H3101  0.36
2000 Koch WJ, Lefkowitz RJ, Rockman HA. Functional consequences of altering myocardial adrenergic receptor signaling. Annual Review of Physiology. 62: 237-60. PMID 10845091 DOI: 10.1146/Annurev.Physiol.62.1.237  0.36
2000 Lipskaia L, Defer N, Esposito G, Hajar I, Garel MC, Rockman HA, Hanoune J. Enhanced cardiac function in transgenic mice expressing a Ca2+- stimulated adenylyl cyclase Circulation Research. 86: 795-801. PMID 10764414 DOI: 10.1161/01.Res.86.7.795  0.36
2000 Lefkowitz RJ, Rockman HA, Koch WJ. Catecholamines, cardiac beta-adrenergic receptors, and heart failure. Circulation. 101: 1634-7. PMID 10758041 DOI: 10.1161/01.Cir.101.14.1634  0.36
2000 Naga Prasad SV, Esposito G, Mao L, Koch WJ, Rockman HA. Gβγ-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy Journal of Biological Chemistry. 275: 4693-4698. PMID 10671499 DOI: 10.1074/Jbc.275.7.4693  0.36
1999 Choi DJ, Rockman HA. β-adrenergic receptor desensitization in cardiac hypertrophy and heart failure Cell Biochemistry and Biophysics. 31: 321-329. PMID 10736754 DOI: 10.1007/Bf02738246  0.36
1999 Koch WJ, Rockman HA. Exploring the role of the β-adrenergic receptor kinase in cardiac disease using gene-targeted mice Trends in Cardiovascular Medicine. 9: 77-81. PMID 10578521 DOI: 10.1016/S1050-1738(99)00009-2  0.36
1999 Akhter SA, Eckhart AD, Rockman HA, Shotwell K, Lefkowitz RJ, Koch WJ. In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function. Circulation. 100: 648-53. PMID 10441103 DOI: 10.1161/01.Cir.100.6.648  0.36
1999 Cho MC, Rapacciuolo A, Koch WJ, Kobayashi Y, Jones LR, Rockman HA. Defective β-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression Journal of Biological Chemistry. 274: 22251-22256. PMID 10428792 DOI: 10.1074/Jbc.274.32.22251  0.36
1999 Cho MC, Rao M, Koch WJ, Thomas SA, Palmiter RD, Rockman HA. Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine. Circulation. 99: 2702-7. PMID 10338466 DOI: 10.1161/01.Cir.99.20.2702  0.36
1999 Rapacciuolo A, Rockman HA. Role of β-adrenoceptor desensitization in heart failure Cardiovascular Drug Reviews. 17: 384-394. DOI: 10.1111/J.1527-3466.1999.Tb00027.X  0.36
1998 Neumann J, Boknik P, DePaoli-Roach AA, Field LJ, Rockman HA, Kobayashi YM, Kelley JS, Jones LR. Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility Journal of Molecular and Cellular Cardiology. 30: 1991-2002. PMID 9799653 DOI: 10.1006/Jmcc.1998.0760  0.36
1998 Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. The Journal of Biological Chemistry. 273: 18180-4. PMID 9660778 DOI: 10.1074/Jbc.273.29.18180  0.36
1998 Rockman HA, Chien KR, Choi DJ, Iaccarino G, Hunter JJ, Ross J, Lefkowitz RJ, Koch WJ. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 7000-5. PMID 9618528 DOI: 10.1073/Pnas.95.12.7000  0.36
1998 Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science (New York, N.Y.). 280: 574-7. PMID 9554846 DOI: 10.1126/Science.280.5363.574  0.36
1998 Koch WJ, Lefkowitz RJ, Milano CA, Akhter SA, Rockman HA. Myocardial overexpression of adrenergic receptors and receptor kinases. Advances in Pharmacology (San Diego, Calif.). 42: 502-6. PMID 9327950  0.36
1998 Iaccarino G, Rockman HA, Shotwell KF, Tomhave ED, Koch WJ. Myocardial overexpression of GRK3 in transgenic mice: Evidence for in vivo selectivity of GRKs American Journal of Physiology - Heart and Circulatory Physiology. 44. DOI: 10.1152/Ajpheart.1998.275.4.H1298  0.36
1997 Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proceedings of the National Academy of Sciences of the United States of America. 94: 14730-5. PMID 9405681 DOI: 10.1073/Pnas.94.26.14730  0.36
1997 Rockman HA. Uncoupling of G-Protein coupled receptors In Vivo: Insights from transgenic mice Advances in Experimental Medicine and Biology. 430: 67-72. PMID 9330719 DOI: 10.1007/978-1-4615-5959-7_6  0.36
1997 Akhter SA, Milano CA, Shotwell KF, Cho MC, Rockman HA, Lefkowitz RJ, Koch WJ. Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling. The Journal of Biological Chemistry. 272: 21253-9. PMID 9261135 DOI: 10.1074/Jbc.272.34.21253  0.36
1997 He H, Giordano FJ, Hilal-Dandan R, Choi DJ, Rockman HA, McDonough PM, Bluhm WF, Meyer M, Sayen MR, Swanson E, Dillmann WH. Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation Journal of Clinical Investigation. 100: 380-389. PMID 9218515 DOI: 10.1172/Jci119544  0.36
1997 Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of β-adrenergic receptor desensitization in cardiac hypertrophy is increased β-adrenergic receptor kinase Journal of Biological Chemistry. 272: 17223-17229. PMID 9202046 DOI: 10.1074/Jbc.272.27.17223  0.36
1997 Sack MN, Disch DL, Rockman HA, Kelly DP. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program Proceedings of the National Academy of Sciences of the United States of America. 94: 6438-6443. PMID 9177236 DOI: 10.1073/Pnas.94.12.6438  0.36
1997 Rockman HA, Koch WJ, Lefkowitz RJ. Cardiac function in genetically engineered mice with altered adrenergic receptor signaling. The American Journal of Physiology. 272: H1553-9. PMID 9139936 DOI: 10.1152/Ajpheart.1997.272.4.H1553  0.36
1997 Ryu KH, Tanaka N, Dalton N, Mao L, Rockman HA, Milano CA, Ross J. Force-frequency relations in the failing rabbit heart and responses to adrenergic stimulation Journal of Cardiac Failure. 3: 27-39. PMID 9110253 DOI: 10.1016/S1071-9164(97)90006-3  0.36
1997 Samama P, Bond RA, Rockman HA, Milano CA, Lefkowitz RJ. Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 137-41. PMID 8990174 DOI: 10.1073/Pnas.94.1.137  0.36
1997 Cho MC, Koch WJ, Rockman HA. Gene therapy for chronic heart failure Acc Current Journal Review. 6: 56-58. DOI: 10.1016/S1062-1458(97)83289-8  0.36
1997 Choi DJ, Koch WJ, Rockman HA. Cardiac hypertrophy is associated with increased β-adrenergic receptor kinase (βARK) Faseb Journal. 11.  0.36
1996 Lembo G, Rockman HA, Hunter JJ, Steinmetz H, Koch WJ, Ma L, Prinz MP, Ross J, Chien KR, Powell-Braxton L. Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency Journal of Clinical Investigation. 98: 2648-2655. PMID 8958230 DOI: 10.1172/Jci119086  0.36
1996 Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 12974-9. PMID 8917529 DOI: 10.1073/Pnas.93.23.12974  0.36
1996 Rockman HA, Koch WJ, Milano CA, Lefkowitz RJ. Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice. Journal of Molecular Medicine (Berlin, Germany). 74: 489-95. PMID 8892053 DOI: 10.1007/Bf00204974  0.36
1996 Rockman HA, Choi DJ, Rahman NU, Akhter SA, Lefkowitz RJ, Koch WJ. Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 9954-9. PMID 8790438 DOI: 10.1073/Pnas.93.18.9954  0.36
1996 Tanaka N, Dalton N, Mao L, Rockman HA, Peterson KL, Gottshall KR, Hunter JJ, Chien KR, Ross J. Transthoracic echocardiography in models of cardiac disease in the mouse Circulation. 94: 1109-1117. PMID 8790053 DOI: 10.1161/01.Cir.94.5.1109  0.36
1996 Swertfeger DK, Witte DP, Stuart WD, Rockman HA, Harmony JAK. Apolipoprotein J/clusterin induction in myocarditis. A localized response gene to myocardial injury American Journal of Pathology. 148: 1971-1983. PMID 8669482  0.36
1996 Rockman HA, Hamilton RA, Jones LR, Milano CA, Mao L, Lefkowitz RJ. Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. The Journal of Clinical Investigation. 97: 1618-23. PMID 8601626 DOI: 10.1172/Jci118587  0.36
1996 Kubalak SW, Hunter JJ, Chien KR, Doevendans PA, Rockman HA, Tanaka N, Ross J. [26]Molecular analysis of cardiac muscle diseases based on mouse genetics Methods in Molecular Genetics. 8: 470-487. DOI: 10.1016/S1067-2389(96)80059-8  0.36
1996 Gulati J, Ben-Yehuda O, Rockman HA. Is cardiac troponin C the length sensor in Starling's law of the heart? (multiple letters) Trends in Cardiovascular Medicine. 6: 245-246. DOI: 10.1016/S1050-1738(96)00104-1  0.36
1996 Ben-Yehuda O, Rockman HA. Regulation of myocardial contractility: Insights from transgenic mice Trends in Cardiovascular Medicine. 6: 95-99. DOI: 10.1016/1050-1738(96)00010-2  0.36
1996 Sack MN, Disch DL, Rader TA, Rockman HA, Kelly DP. Transcriptional downregulation of a mitochondria!. fatty acid oxidation enzyme gene in response to ventricular pressure overload Journal of Investigative Medicine. 44.  0.36
1995 Penny WF, Rockman H, Long J, Bhargava V, Carrigan K, Ibriham A, Shabetai R, Ross J, Peterson KL. Heterogeneity of vasomotor response to acetylcholine along the human coronary artery Journal of the American College of Cardiology. 25: 1046-1055. PMID 7897115 DOI: 10.1016/0735-1097(94)00537-Z  0.36
1995 Bond RA, Leff P, Johnson TD, Milano CA, Rockman HA, McMinn TR, Apparsundaram S, Hyek MF, Kenakin TP, Allen LF, Lefkowitz RJ. Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor Nature. 374: 272-276. PMID 7885448 DOI: 10.1038/374272A0  0.36
1995 Milano CA, Allen LF, Dolber PC, Johnson TD, Rockman HA, Bond RA, Lefkowitz RJ. Marked enhancement in myocardial function resulting from overexpression of a human β-adrenergic receptor gene The Journal of Thoracic and Cardiovascular Surgery. 109: 236-241. PMID 7853876 DOI: 10.1016/S0022-5223(95)70384-5  0.36
1995 Knowlton KU, Rockman HA, Itani M, Vovan A, Seidman CE, Chien KR. Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium Journal of Clinical Investigation. 96: 1311-1318. PMID 7657806 DOI: 10.1172/Jci118166  0.36
1995 Koch WJ, Rockman HA, Samama P, Hamilton RA, Bond RA, Milano CA, Lefkowitz RJ. Cardiac function in mice overexpressing the β-adrenergic receptor kinase or a βARK inhibitor Circulation. 92: 277. PMID 7634434  0.36
1995 Lin MC, Rockman HA, Chien KR. Heart and lung disease in engineered mice Nature Medicine. 1: 749-751. PMID 7585174 DOI: 10.1038/Nm0895-749  0.36
1995 Hunter JJ, Tanaka N, Rockman HA, Ross J, Chien KR. Ventricular expression of a mlc-2v-ras fusion gene induces cardiac hypertrophy selective diastolic dysfunction in transgenic mice Journal of Biological Chemistry. 270: 23173-23178. PMID 7559464 DOI: 10.1074/Jbc.270.39.23173  0.36
1994 Ono S, Bhargava V, Mao L, Hagan G, Rockman HA, Ross J. In vivo assessment of left ventricular remodelling after myocardial infarction by digital video contrast angiography in the rat Cardiovascular Research. 28: 349-357. PMID 8174155 DOI: 10.1093/Cvr/28.3.349  0.36
1994 Omens JH, Rockman HA, Covell JW. Passive ventricular mechanics in tight-skin mice American Journal of Physiology - Heart and Circulatory Physiology. 266: H1169-H1176. PMID 8160820 DOI: 10.1152/Ajpheart.1994.266.3.H1169  0.36
1994 Milano CA, Allen LF, Rockman HA, Dolber PC, McMinn TR, Chien KR, Johnson TD, Bond RA, Lefkowitz RJ. Enhanced myocardial function in transgenic mice overexpressing the β2-adrenergic receptor Science. 264: 582-586. PMID 8160017 DOI: 10.1126/Science.8160017  0.36
1994 Rockman HA, Ono S, Ross RS, Jones LR, Karimi M, Bhargava V, Ross J, Chien KR. Molecular and physiological alterations in murine ventricular dysfunction Proceedings of the National Academy of Sciences of the United States of America. 91: 2694-2698. PMID 8146176 DOI: 10.1073/Pnas.91.7.2694  0.36
1994 Rockman HA, Wachhorst SP, Mao L, Ross J. ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice American Journal of Physiology - Heart and Circulatory Physiology. 266. PMID 8024008 DOI: 10.1152/Ajpheart.1994.266.6.H2468  0.36
1994 Milano CA, Dolber PC, Rockman HA, Bond RA, Venable ME, Allen LF, Lefkowitz RJ. Myocardial expression of a constitutively active α1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy Proceedings of the National Academy of Sciences of the United States of America. 91: 10109-10113. PMID 7937846 DOI: 10.1073/Pnas.91.21.10109  0.36
1993 Oh BH, Ono S, Rockman HA, Ross J. Myocardial hypertrophy in the ischemic zone induced by exercise in rats after coronary reperfusion Circulation. 87: 598-607. PMID 8425304 DOI: 10.1161/01.Cir.87.2.598  0.36
1993 Rockman HA, Knowlton KU, Ross J, Chien KR. In vivo murine cardiac hypertrophy: A novel model to identify genetic signaling mechanisms that activate an adaptive physiological response Circulation. 87.  0.36
1992 Kambayashi M, Miura T, Oh BH, Murata K, Rockman HA, Parra G, Ross J. Myocardial cell hypertrophy after myocardial infarction with reperfusion in dogs Circulation. 86: 1935-1944. PMID 1451265 DOI: 10.1161/01.Cir.86.6.1935  0.36
1992 Oh BH, Volpini M, Kambayashi M, Murata K, Rockman HA, Kassab GS, Ross J. Myocardial function and transmural blood flow during coronary venous retroperfusion in pigs Circulation. 86: 1265-1279. PMID 1394933 DOI: 10.1161/01.Cir.86.4.1265  0.36
1992 Lee KJ, Ross RS, Rockman HA, Harris AN, O'Brien TX, van Bilsen M, Shubeita HE, Kandolf R, Brem G, Price J. Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. The Journal of Biological Chemistry. 267: 15875-85. PMID 1379240  0.36
1992 Kambayashi M, Miura T, Oh BH, Rockman HA, Murata K, Ross J. Enhancement of the force-frequency effect on myocardial contractility by adrenergic stimulation in conscious dogs Circulation. 86: 572-580. PMID 1353420 DOI: 10.1161/01.Cir.86.2.572  0.36
1992 Rockman HA, Knowlton KU. Peripartum vascular collapse. Dissection of a genetic disease Trends in Cardiovascular Medicine. 2: 125-128. DOI: 10.1016/1050-1738(92)90018-N  0.36
1991 Rockman HA, Adamson RM, Dembitsky WP, Bonar JW, Jaski BE. Acute fulminant myocarditis: Long-term follow-up after circulatory support with left ventricular assist device American Heart Journal. 121: 922-926. PMID 2000764 DOI: 10.1016/0002-8703(91)90213-2  0.36
1991 Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J, Chien KR. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 88: 8277-81. PMID 1832775 DOI: 10.1073/Pnas.88.18.8277  0.36
1991 Miyamoto MI, Rockman HA, Guth BD, Heusch G, Ross J. Effect of α-adrenergic stimulation on regional contractile function and myocardial blood flow with and without ischemia Circulation. 84: 1715-1724. PMID 1680577 DOI: 10.1161/01.Cir.84.4.1715  0.36
1989 Rockman HA, Juneau C, Chatterjee K, Rouleau JL. Long-term predictors of sudden and low output death in chronic congestive heart failure secondary to coronary artery disease The American Journal of Cardiology. 64: 1344-1348. PMID 2589201 DOI: 10.1016/0002-9149(89)90579-1  0.36
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