Andre J. Ouellette - Publications

Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Immunology, Biochemistry, Microbiology Biology, Cell Biology

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Basso V, Tran DQ, Ouellette AJ, Selsted ME. Host Defense Peptides as Templates for Antifungal Drug Development. Journal of Fungi (Basel, Switzerland). 6. PMID 33113935 DOI: 10.3390/jof6040241  0.44
2019 Tongaonkar P, Punj V, Subramanian A, Tran D, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME. RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts. Physiological Genomics. PMID 31762409 DOI: 10.1152/physiolgenomics.00066.2019  0.44
2019 Basso V, Tran DQ, Schaal JB, Tran P, Eriguchi Y, Ngole D, Cabebe AE, Park AY, Beringer PM, Ouellette AJ, Selsted ME. Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms. Scientific Reports. 9: 16905. PMID 31729441 DOI: 10.1038/s41598-019-53402-z  0.44
2018 Cobo ER, Holani R, Moreau F, Nakamura K, Ayabe T, Mastroianni JR, Eriguchi Y, Ouellette A, Chadee K. Correction for Cobo et al., "Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency". Infection and Immunity. 86. PMID 30242014 DOI: 10.1128/IAI.00564-18  0.96
2018 Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, Teshima T, Ayabe T, Selsted ME, Ouellette AJ. Essential role of IFN-γ in T cell-associated intestinal inflammation. Jci Insight. 3. PMID 30232288 DOI: 10.1172/jci.insight.121886  0.44
2018 Cobo ER, Holani R, Moreau F, Nakamura K, Ayabe T, Mastroianni JR, Ouellette A, Chadee K. Alters ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency. Infection and Immunity. PMID 29685982 DOI: 10.1128/IAI.00208-18  0.96
2018 Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME. Fungicidal potency and mechanisms of θ-defensins against multi-drug resistantspecies. Antimicrobial Agents and Chemotherapy. PMID 29610196 DOI: 10.1128/AAC.00111-18  0.44
2018 Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME. Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α converting enzyme. The Journal of Biological Chemistry. PMID 29317500 DOI: 10.1074/jbc.RA117.000793  0.44
2017 Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME. Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide. Plos One. 12: e0187868. PMID 29145473 DOI: 10.1371/journal.pone.0187868  0.44
2016 Nevins AM, Subramanian A, Tapia JL, Delgado DP, Tyler RC, Jensen DR, Ouellette AJ, Volkman BF. A Requirement for Metamorphic Interconversion in the Antimicrobial Activity of the Chemokine XCL1. Biochemistry. PMID 27305837 DOI: 10.1021/acs.biochem.6b00353  0.96
2016 Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, et al. Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration. Cell Host & Microbe. 19: 814-825. PMID 27281571 DOI: 10.1016/j.chom.2016.05.005  0.96
2016 Gounder AP, Myers ND, Treuting PM, Bromme BA, Wilson SS, Wiens ME, Lu W, Ouellette AJ, Spindler KR, Parks WC, Smith JG. Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection. Plos Pathogens. 12: e1005474. PMID 26933888 DOI: 10.1371/journal.ppat.1005474  0.96
2015 Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME. Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways. Journal of Leukocyte Biology. PMID 26269197 DOI: 10.1189/jlb.3A0315-102R  0.96
2015 Tai KP, Kamdar K, Yamaki J, Le VV, Tran D, Tran P, Selsted ME, Ouellette AJ, Wong-Beringer A. Microbicidal effects of α- and θ-defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Innate Immunity. 21: 17-29. PMID 24345876 DOI: 10.1177/1753425913514784  0.96
2015 Ouellette AJ. Defensins in Enteric Mucosal Immunity Mucosal Immunology: Fourth Edition. 1: 271-285. DOI: 10.1016/B978-0-12-415847-4.00016-1  0.96
2014 Wilmes M, Stockem M, Bierbaum G, Schlag M, Götz F, Tran DQ, Schaal JB, Ouellette AJ, Selsted ME, Sahl HG. Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymes. Antibiotics (Basel, Switzerland). 3: 617-631. PMID 25632351 DOI: 10.3390/antibiotics3040617  0.44
2014 Mastroianni JR, Lu W, Selsted ME, Ouellette AJ. Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions. Antibiotics (Basel, Switzerland). 3: 493-508. PMID 25383215 DOI: 10.3390/antibiotics3040493  0.96
2014 Tai KP, Le VV, Selsted ME, Ouellette AJ. Hydrophobic determinants of α-defensin bactericidal activity. Infection and Immunity. 82: 2195-202. PMID 24614658 DOI: 10.1128/IAI.01414-13  0.96
2013 Patil AA, Ouellette AJ, Lu W, Zhang G. Rattusin, an intestinal α-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities. Antimicrobial Agents and Chemotherapy. 57: 1823-31. PMID 23380721 DOI: 10.1128/AAC.02237-12  0.96
2013 Ouellette AAJ, Selsted ME. Paneth Cell α-Defensins Handbook of Biologically Active Peptides. 1300-1306. DOI: 10.1016/B978-0-12-385095-9.00177-9  0.44
2012 Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME. Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. Plos One. 7: e51337. PMID 23236475 DOI: 10.1371/journal.pone.0051337  0.96
2012 Anand P, Cermelli S, Li Z, Kassan A, Bosch M, Sigua R, Huang L, Ouellette AJ, Pol A, Welte MA, Gross SP. A novel role for lipid droplets in the organismal antibacterial response. Elife. 1: e00003. PMID 23150794 DOI: 10.7554/eLife.00003  0.96
2012 Park SW, Kim M, Kim JY, Ham A, Brown KM, Mori-Akiyama Y, Ouellette AJ, D'Agati VD, Lee HT. Paneth cell-mediated multiorgan dysfunction after acute kidney injury. Journal of Immunology (Baltimore, Md. : 1950). 189: 5421-33. PMID 23109723 DOI: 10.4049/jimmunol.1200581  0.96
2012 Ouellette AJ, Selsted ME. Immunology. HD6 defensin nanonets. Science (New York, N.Y.). 337: 420-1. PMID 22837514 DOI: 10.1126/science.1225906  0.96
2012 Burkhardt AM, Tai KP, Flores-Guiterrez JP, Vilches-Cisneros N, Kamdar K, Barbosa-Quintana O, Valle-Rios R, Hevezi PA, Zuñiga J, Selman M, Ouellette AJ, Zlotnik A. CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity. Journal of Immunology (Baltimore, Md. : 1950). 188: 6399-406. PMID 22611239 DOI: 10.4049/jimmunol.1102903  0.96
2012 Schmidt NW, Tai KP, Kamdar K, Mishra A, Lai GH, Zhao K, Ouellette AJ, Wong GC. Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior. The Journal of Biological Chemistry. 287: 21866-72. PMID 22566697 DOI: 10.1074/jbc.M112.358721  0.96
2012 Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME. High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3. Plos One. 7: e32469. PMID 22448222 DOI: 10.1371/journal.pone.0032469  0.96
2012 Mastroianni JR, Costales JK, Zaksheske J, Selsted ME, Salzman NH, Ouellette AJ. Alternative luminal activation mechanisms for paneth cell α-defensins. The Journal of Biological Chemistry. 287: 11205-12. PMID 22334698 DOI: 10.1074/jbc.M111.333559  0.96
2012 Andersson HS, Figueredo SM, Haugaard-Kedström LM, Bengtsson E, Daly NL, Qu X, Craik DJ, Ouellette AJ, Rosengren KJ. The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids. 43: 1471-83. PMID 22286872 DOI: 10.1007/s00726-012-1220-3  0.96
2011 Garcia AE, Tai KP, Puttamadappa SS, Shekhtman A, Ouellette AJ, Camarero JA. Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins. Biochemistry. 50: 10508-19. PMID 22040603 DOI: 10.1021/bi201430f  0.96
2011 Ouellette AJ. Paneth cell α-defensins in enteric innate immunity Cellular and Molecular Life Sciences. 68: 2215-2229. PMID 21560070 DOI: 10.1007/s00018-011-0714-6  0.96
2011 Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC. Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. Journal of the American Chemical Society. 133: 6720-7. PMID 21473577 DOI: 10.1021/ja200079a  0.96
2011 Mishra A, Tai KP, Schmidt NW, Ouellette AJ, Wong GC. Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell α-defensin cryptdin-4. Methods in Enzymology. 492: 127-49. PMID 21333790 DOI: 10.1016/B978-0-12-381268-1.00016-1  0.96
2011 Zaragoza MM, Sankaran-Walters S, Canfield DR, Hung JK, Martinez E, Ouellette AJ, Dandekar S. Persistence of gut mucosal innate immune defenses by enteric α-defensin expression in the simian immunodeficiency virus model of AIDS. Journal of Immunology (Baltimore, Md. : 1950). 186: 1589-97. PMID 21178012 DOI: 10.4049/jimmunol.1002021  0.96
2011 Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME. Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities. Journal of Leukocyte Biology. 89: 283-90. PMID 21084627 DOI: 10.1189/jlb.0910535  0.96
2011 Shanahan MT, Tanabe H, Ouellette AJ. Strain-specific polymorphisms in Paneth cell α-defensins of C57BL/6 mice and evidence of vestigial myeloid α-defensin pseudogenes. Infection and Immunity. 79: 459-73. PMID 21041494 DOI: 10.1128/IAI.00996-10  0.96
2010 Ouellette AJ. Paneth cells and innate mucosal immunity. Current Opinion in Gastroenterology. 26: 547-53. PMID 20693892 DOI: 10.1097/MOG.0b013e32833dccde  0.96
2010 Figueredo S, Mastroianni JR, Tai KP, Ouellette AJ. Expression and purification of recombinant alpha-defensins and alpha-defensin precursors in Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 618: 47-60. PMID 20094857 DOI: 10.1007/978-1-60761-594-1_4  0.96
2010 Shanahan MT, Vidrich A, Shirafuji Y, Dubois CL, Henschen-Edman A, Hagen SJ, Cohn SM, Ouellette AJ. Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action. The Journal of Biological Chemistry. 285: 7493-504. PMID 20056603 DOI: 10.1074/jbc.M109.083220  0.96
2010 Zhao F, Edwards R, Dizon D, Afrasiabi K, Mastroianni JR, Geyfman M, Ouellette AJ, Andersen B, Lipkin SM. Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Developmental Biology. 338: 270-9. PMID 20025862 DOI: 10.1016/j.ydbio.2009.12.008  0.96
2010 Figueredo SM, Ouellette AJ. Inhibition of bactericidal activity is maintained in a mouse alpha-defensin precursor with proregion truncations. Peptides. 31: 9-15. PMID 19837119 DOI: 10.1016/j.peptides.2009.10.004  0.96
2010 Ouellette AJ, Niklas V. Paneth cells in intestinal health and disease in the newborn Neoreviews. 11. DOI: 10.1542/neo.11-10-e551  0.96
2009 Llenado RA, Weeks CS, Cocco MJ, Ouellette AJ. Electropositive charge in alpha-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure. Infection and Immunity. 77: 5035-43. PMID 19737896 DOI: 10.1128/IAI.00695-09  0.96
2009 Mastroianni JR, Ouellette AJ. Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen. The Journal of Biological Chemistry. 284: 27848-56. PMID 19687006 DOI: 10.1074/jbc.M109.050773  0.96
2009 Figueredo SM, Weeks CS, Young SK, Ouellette AJ. Anionic amino acids near the pro-alpha-defensin N terminus mediate inhibition of bactericidal activity in mouse pro-cryptdin-4. The Journal of Biological Chemistry. 284: 6826-31. PMID 19106102 DOI: 10.1074/jbc.M807024200  0.96
2008 Hadjicharalambous C, Sheynis T, Jelinek R, Shanahan MT, Ouellette AJ, Gizeli E. Mechanisms of alpha-defensin bactericidal action: comparative membrane disruption by Cryptdin-4 and its disulfide-null analogue. Biochemistry. 47: 12626-34. PMID 18973303 DOI: 10.1021/bi800335e  0.96
2008 Kamdar K, Maemoto A, Qu X, Young SK, Ouellette AJ. In vitro activation of the rhesus macaque myeloid alpha-defensin precursor proRMAD-4 by neutrophil serine proteinases. The Journal of Biological Chemistry. 283: 32361-8. PMID 18775986 DOI: 10.1074/jbc.M805296200  0.96
2008 Tran D, Tran P, Roberts K, Osapay G, Schaal J, Ouellette A, Selsted ME. Microbicidal properties and cytocidal selectivity of rhesus macaque theta defensins. Antimicrobial Agents and Chemotherapy. 52: 944-53. PMID 18160518 DOI: 10.1128/AAC.01090-07  0.96
2008 Miszta A, Machán R, Benda A, Ouellette AJ, Hermens WT, Hof M. Combination of ellipsometry, laser scanning microscopy and Z-scan fluorescence correlation spectroscopy elucidating interaction of cryptdin-4 with supported phospholipid bilayers. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 503-9. PMID 17994618 DOI: 10.1002/psc.938  0.96
2007 Shi J, Aono S, Lu W, Ouellette AJ, Hu X, Ji Y, Wang L, Lenz S, van Ginkel FW, Liles M, Dykstra C, Morrison EE, Elson CO. A novel role for defensins in intestinal homeostasis: regulation of IL-1beta secretion. Journal of Immunology (Baltimore, Md. : 1950). 179: 1245-53. PMID 17617617  0.96
2006 Ouellette AJ. Paneth cell α-defensin synthesis and function Current Topics in Microbiology and Immunology. 306: 1-25. PMID 16909916  0.96
2006 Rosengren KJ, Daly NL, Fornander LM, Jönsson LM, Shirafuji Y, Qu X, Vogel HJ, Ouellette AJ, Craik DJ. Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4. The Journal of Biological Chemistry. 281: 28068-78. PMID 16857681 DOI: 10.1074/jbc.M604992200  0.96
2006 Weeks CS, Tanabe H, Cummings JE, Crampton SP, Sheynis T, Jelinek R, Vanderlick TK, Cocco MJ, Ouellette AJ. Matrix metalloproteinase-7 activation of mouse paneth cell pro-alpha-defensins: SER43 down arrow ILE44 proteolysis enables membrane-disruptive activity. The Journal of Biological Chemistry. 281: 28932-42. PMID 16822871 DOI: 10.1074/jbc.M602041200  0.96
2006 Ouellette AJ. Paneth Cell Α-Defensins Handbook of Biologically Active Peptides. 1029-1035. DOI: 10.1016/B978-012369442-3/50144-6  0.96
2005 Ouellette AJ. Paneth cell alpha-defensins: peptide mediators of innate immunity in the small intestine. Springer Seminars in Immunopathology. 27: 133-46. PMID 15931529 DOI: 10.1007/s00281-005-0202-x  0.96
2005 Selsted ME, Ouellette AJ. Mammalian defensins in the antimicrobial immune response. Nature Immunology. 6: 551-7. PMID 15908936 DOI: 10.1038/ni1206  0.96
2005 Crouch ML, Becker LA, Bang IS, Tanabe H, Ouellette AJ, Fang FC. The alternative sigma factor sigma is required for resistance of Salmonella enterica serovar Typhimurium to anti-microbial peptides. Molecular Microbiology. 56: 789-99. PMID 15819632 DOI: 10.1111/j.1365-2958.2005.04578.x  0.96
2005 Tanabe H, Ayabe T, Bainbridge B, Guina T, Ernst RK, Darveau RP, Miller SI, Ouellette AJ. Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria. Infection and Immunity. 73: 2312-20. PMID 15784576 DOI: 10.1128/IAI.73.4.2312-2320.2005  0.96
2004 Jing W, Hunter HN, Tanabe H, Ouellette AJ, Vogel HJ. Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin. Biochemistry. 43: 15759-66. PMID 15595831 DOI: 10.1021/bi048645p  0.96
2004 Tanabe H, Ouellette AJ, Cocco MJ, Robinson WE. Differential effects on human immunodeficiency virus type 1 replication by alpha-defensins with comparable bactericidal activities. Journal of Virology. 78: 11622-31. PMID 15479803 DOI: 10.1128/JVI.78.21.11622-11631.2004  0.96
2004 Maemoto A, Qu X, Rosengren KJ, Tanabe H, Henschen-Edman A, Craik DJ, Ouellette AJ. Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4. The Journal of Biological Chemistry. 279: 44188-96. PMID 15297466 DOI: 10.1074/jbc.M406154200  0.96
2004 Ouellette AJ. Defensin-mediated innate immunity in the small intestine. Best Practice & Research. Clinical Gastroenterology. 18: 405-19. PMID 15123078 DOI: 10.1016/j.bpg.2003.10.010  0.96
2004 Lin PW, Simon PO, Gewirtz AT, Neish AS, Ouellette AJ, Madara JL, Lencer WI. Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response. The Journal of Biological Chemistry. 279: 19902-7. PMID 14990585 DOI: 10.1074/jbc.M311821200  0.96
2004 Tanabe H, Yuan J, Zaragoza MM, Dandekar S, Henschen-Edman A, Selsted ME, Ouellette AJ. Paneth cell alpha-defensins from rhesus macaque small intestine. Infection and Immunity. 72: 1470-8. PMID 14977952 DOI: 10.1128/IAI.72.3.1470-1478.2004  0.96
2004 Clarke LL, Gawenis LR, Bradford EM, Judd LM, Boyle KT, Simpson JE, Shull GE, Tanabe H, Ouellette AJ, Franklin CL, Walker NM. Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G1050-8. PMID 14715526 DOI: 10.1152/ajpgi.00393.2003  0.96
2004 Tanabe H, Qu X, Weeks CS, Cummings JE, Kolusheva S, Walsh KB, Jelinek R, Vanderlick TK, Selsted ME, Ouellette AJ. Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions. The Journal of Biological Chemistry. 279: 11976-83. PMID 14702345 DOI: 10.1074/jbc.M310251200  0.96
2003 Satchell DP, Sheynis T, Kolusheva S, Cummings J, Vanderlick TK, Jelinek R, Selsted ME, Ouellette AJ. Quantitative interactions between cryptdin-4 amino terminal variants and membranes. Peptides. 24: 1795-805. PMID 15019212 DOI: 10.1016/j.peptides.2003.08.020  0.96
2003 Satchell DP, Sheynis T, Shirafuji Y, Kolusheva S, Ouellette AJ, Jelinek R. Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes. The Journal of Biological Chemistry. 278: 13838-46. PMID 12574157 DOI: 10.1074/jbc.M212115200  0.96
2003 Shirafuji Y, Tanabe H, Satchell DP, Henschen-Edman A, Wilson CL, Ouellette AJ. Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase-7. The Journal of Biological Chemistry. 278: 7910-9. PMID 12482850 DOI: 10.1074/jbc.M210600200  0.96
2003 Cummings JE, Satchell DP, Shirqfuji Y, Ouellette AJ, Vanderlick TK. Electrostatically Controlled Interactions of Mouse Paneth Cell α-Defensins with Phospholipid Membranes Australian Journal of Chemistry. 56: 1031-1034. DOI: 10.1071/CH03110  0.96
2002 Ayabe T, Satchell DP, Pesendorfer P, Tanabe H, Wilson CL, Hagen SJ, Ouellette AJ. Activation of Paneth cell alpha-defensins in mouse small intestine. The Journal of Biological Chemistry. 277: 5219-28. PMID 11733520 DOI: 10.1074/jbc.M109410200  0.96
2002 Ayabe T, Wulff H, Darmoul D, Cahalan MD, Chandy KG, Ouellette AJ. Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel. The Journal of Biological Chemistry. 277: 3793-800. PMID 11724775 DOI: 10.1074/jbc.M107507200  0.96
2001 Kamal M, Wakelin D, Ouellette AJ, Smith A, Podolsky DK, Mahida YR. Mucosal T cells regulate paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice Clinical and Experimental Immunology. 126: 117-125. PMID 11678907 DOI: 10.1046/j.1365-2249.2001.01589.x  0.96
2001 Robertson DJ, Sandler RS. Measles virus and Crohn's disease: a critical appraisal of the current literature. Inflammatory Bowel Diseases. 7: 51-7. PMID 11233661 DOI: 10.1097/00054725-200102000-00008  0.96
2000 Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nature Immunology. 1: 113-8. PMID 11248802 DOI: 10.1038/77783  0.96
2000 Ouellette AJ, Satchell DP, Hsieh MM, Hagen SJ, Selsted ME. Characterization of luminal Paneth cell α-defensins in mouse small intestine: Attenuated antimicrobial activities of peptides with truncated amino termini Journal of Biological Chemistry. 275: 33969-33973. PMID 10942762 DOI: 10.1074/jbc.M004062200  0.96
2000 Lencer WI, Merlin D, Ouellette AJ, Selsted ME, Madara JL. Natural pore forming proteins: Paneth cell cryptdins Acs Symposium Series. 752: 149-156.  0.96
1999 Ouellette AJ, Darmoul D, Tran D, Huttner KM, Yuan J, Selsted ME. Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse Paneth cell α-defensin Infection and Immunity. 67: 6643-6651. PMID 10569786  0.96
1999 Tang YQ, Yuan J, Ösapay G, Ösapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME. A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated α-defensins Science. 286: 498-502. PMID 10521339 DOI: 10.1126/science.286.5439.498  0.96
1999 Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, López-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science (New York, N.Y.). 286: 113-7. PMID 10506557 DOI: 10.1126/science.286.5437.113  0.96
1999 Ouellette AJ. Mucosal immunity and inflammation. IV. Paneth cell antimicrobial peptides and the biology of the mucosal barrier American Journal of Physiology - Gastrointestinal and Liver Physiology. 277. PMID 10444437 DOI: 10.1152/ajpgi.1999.277.2.G257  0.96
1998 Ouellette AJ. Peptide mediators of innate immunity in the small intestine Journal of Medical Microbiology. 47: 941-942. PMID 9822294  0.96
1997 Ouellette AJ. Paneth cells and innate immunity in the crypt microenvironment Gastroenterology. 113: 1779-1784. PMID 9352884 DOI: 10.1053/gast.1997.v113.pm9352884  0.96
1997 Lencer WI, Cheung G, Strohmeier GR, Currie MG, Ouellette AJ, Selsted ME, Madara JL. Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3. Proceedings of the National Academy of Sciences of the United States of America. 94: 8585-9. PMID 9238020 DOI: 10.1073/pnas.94.16.8585  0.96
1997 Darmoul D, Brown D, Selsted ME, Ouellette AJ. Cryptdin gene expression in developing mouse small intestine American Journal of Physiology - Gastrointestinal and Liver Physiology. 272. PMID 9038894  0.96
1997 Ouellette AJ, Selsted ME. Enteric defensins Current Opinion in Gastroenterology. 13: 494-499.  0.96
1996 Ouellette AJ, Selsted ME. Paneth cell defensins: Endogenous peptide components of intestinal host defense Faseb Journal. 10: 1280-1289. PMID 8836041  0.96
1996 Darmoul D, Ouellette AJ. Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine American Journal of Physiology - Gastrointestinal and Liver Physiology. 271. PMID 8760109  0.96
1995 Yount NY, Wang MSC, Yuan J, Banaiee N, Ouellette AJ, Selsted ME. Rat neutrophil defensins - Precursor structures and expression during neutrophilic myelopoiesis Journal of Immunology. 155: 4476-4484. PMID 7594610  0.96
1995 Selsted ME, Ouellette AJ. Defensins in granules of phagocytic and non-phagocytic cells Trends in Cell Biology. 5: 114-119. DOI: 10.1016/S0962-8924(00)88961-8  0.96
1994 Huttner KM, Selsted ME, Ouellette AJ. Structure and Diversity of the Murine Cryptdin Gene Family Genomics. 19: 448-453. PMID 8188287 DOI: 10.1006/geno.1994.1093  0.96
1994 Ouellette AJ, Lauldi JC. A novel gene family coding for cationic, cysteine-rich peptides. Regulation in mouse small intestine and cells of myeloid origin Journal of Biological Chemistry. 269: 18702. PMID 8034619  0.96
1994 Ouellette AJ, Hsieh MM, Nosek MT, Cano-Gauci DF, Huttner KM, Buick RN, Selsted ME. Mouse Paneth cell defensins: Primary structures and antibacterial activities of numerous cryptdin isoforms Infection and Immunity. 62: 5040-5047. PMID 7927786  0.96
1994 Huttner KM, Ouellette AJ. A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells Genomics. 24: 99-109. PMID 7896294 DOI: 10.1006/geno.1994.1586  0.96
1993 Sanderson IR, Ouellette AJ, Carter EA, Harmatz PR. Ontogeny of la messenger RNA in the mouse small intestinal epithelium is modulated by age of weaning and diet Gastroenterology. 105: 974-980. PMID 8405883  0.96
1993 Witzgall R, O'Leary E, Gessner R, Ouellette AJ, Bonventre JV. Kid-1, a putative renal transcription factor: Regulation during ontogeny and in response to ischemia and toxic injury Molecular and Cellular Biology. 13: 1933-1942. PMID 8382778  0.96
1993 Sanderson IR, Ouellette AJ, Carter EA, Walker WA, Harmatz PR. Differential regulation of B7 mRNA in enterocytes and lymphoid cells Immunology. 79: 434-438. PMID 7691725  0.96
1993 Cano-Gauci DF, Lualdi JC, Ouellette AJ, Brady G, Iscove NN, Buick RN. In vitro cDNA amplification from individual intestinal crypts: A novel approach to the study of differential gene expression along the crypt-villus axis Experimental Cell Research. 208: 344-349. PMID 7690709 DOI: 10.1006/excr.1993.1255  0.96
1992 Sellmayer A, Krane SM, Ouellette AJ, Bonventre JV. 1 alpha,25-(OH)2 vitamin D3 enhances expression of the genes encoding Ca(2+)-binding proteins MRP-8 and MRP-14. The American Journal of Physiology. 262: C235-42. PMID 1733233  0.96
1992 Ouellette AJ, Miller SI, Henschen AH, Selsted ME. Purification and primary structure of murine cryptdin-1, a Paneth cell defensin Febs Letters. 304: 146-148. PMID 1618314 DOI: 10.1016/0014-5793(92)80606-H  0.96
1992 Selsted ME, Miller SI, Henschen AH, Ouellette AJ. Enteric defensins: Antibiotic peptide components of intestinal host defense Journal of Cell Biology. 118: 929-936. PMID 1500431 DOI: 10.1083/jcb.118.4.929  0.96
1992 Lin MY, Munshi IA, Ouellette AJ. The defensin-related murine CRS1C gene: Expression in paneth cells and linkage to Defcr, the cryptdin locus Genomics. 14: 363-368. PMID 1427853 DOI: 10.1016/S0888-7543(05)80227-7  0.96
1992 Sanderson IR, Ouellette AJ, Carter EA, Harmatz PR. Ontogeny of class II MHC mRNA in the mouse small intestinal epithelium Molecular Immunology. 29: 1257-1263. PMID 1326714 DOI: 10.1016/0161-5890(92)90062-3  0.96
1991 Bonventre JV, Sukhatme VP, Bamberger M, Ouellette AJ, Brown D. Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion Cell Regulation. 2: 251-260. PMID 1859855  0.96
1991 Ouellette AJ, Frederick D, Hagen SJ, Katz JD. Class II antigen-associated invariant chain mRNA in mouse small intestine. Biochemical and Biophysical Research Communications. 179: 1642-8. PMID 1718272 DOI: 10.1016/0006-291X(91)91763-3  0.96
1990 Ouellette AJ, Malt RA, Sukhatme VP, Bonventre JV. Expression of two 'immediate early' genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice Journal of Clinical Investigation. 85: 766-771. PMID 2107209  0.96
1989 Ouellette AJ, Greco RM, James M, Frederick D, Naftilan J, Fallon JT. Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium. The Journal of Cell Biology. 108: 1687-95. PMID 2715173  0.96
1989 Ouellette AJ, Pravtcheva D, Ruddle FH, James M. Localization of the cryptdin locus on mouse chromosome 8 Genomics. 5: 233-239. PMID 2571573 DOI: 10.1016/0888-7543(89)90051-7  0.96
1989 Weitzman SA, Lee RM, Ouellette AJ. Alterations in c-abl gene methylation in cells transformed by phagocyte-generated oxidants Biochemical and Biophysical Research Communications. 158: 24-30. PMID 2563223 DOI: 10.1016/S0006-291X(89)80171-8  0.96
1988 Ouellette AJ, Cordell B. Accumulation of abundant messenger ribonucleic acids during postnatal development of mouse small intestine Gastroenterology. 94: 114-121. PMID 3335283  0.96
1988 Russell WE, Coffey RJ, Ouellette AJ, Moses HL. Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat Proceedings of the National Academy of Sciences of the United States of America. 85: 5126-5130. PMID 3164865  0.96
1987 Ouellette AJ, Moonka R, Zelenetz AD, Malt RA. Regulation of ribosome synthesis during compensatory renal hypertrophy in mice American Journal of Physiology - Cell Physiology. 253. PMID 3661693  0.96
1984 Pratt RE, Dzau VJ, Ouellette AJ. Influence of androgen on translatable renin mRNA in the mouse submandibular gland Hypertension. 6: 605-613. PMID 6389334  0.96
1983 Ouellette AJ, Watson RK, Billmire K, Dygert MK, Ingwall JS. Protein synthesis in the cultured fetal mouse heart: Effects of deprivation of oxygen and oxidizable substrate Biochemistry. 22: 1201-1207. PMID 6838848  0.96
1983 Ouellette AJ, Croall DE, Van Ness J, Ingwall JS. Developmental regulation of mRNA in mouse heart Proceedings of the National Academy of Sciences of the United States of America. 80: 223-227. PMID 6571996  0.96
1983 Ouellette AJ. Messenger RNA regulation during compensatory renal growth Kidney International. 23: 575-580. PMID 6571410  0.96
1983 Pratt RE, Ouellette AJ, Dzau VJ. Biosynthesis of renin: Multiplicity of active and intermediate forms Proceedings of the National Academy of Sciences of the United States of America. 80: 6809-6813. PMID 6139811  0.96
1982 Ouellette AJ, Aviles L, Burnweit CA, Frederick D, Malt RA. Metallothionein mRNA induction in mouse small bowel by oral cadmium and zinc. The American Journal of Physiology. 243: G396-403. PMID 6127954  0.96
1982 Ouellette AJ. Metallothionein mRNA expression in fetal mouse organs Developmental Biology. 92: 240-246. PMID 6125446 DOI: 10.1016/0012-1606(82)90168-3  0.96
1982 Ouellette AJ, Ordahl CP, Van Ness J, Malt RA. Mouse kidney nonpolysomal messenger ribonucleic acid: Metabolism, coding function, and translational activity Biochemistry. 21: 1169-1177. PMID 6122465  0.96
1982 Ouellette AJ, Aviles L, Burnweit CA. Metallothionein mRNA induction in mouse small bowel by oral cadmium and zinc American Journal of Physiology - Gastrointestinal and Liver Physiology. 6.  0.96
1982 Aviles L, Burnweit CA, Frederick D, Ouellette AJ. metallothionein mRNA in mouse small intestine exposed to cadmium and zinc Federation Proceedings. 41: No. 2174.  0.96
1981 Pratt RE, Dzau VJ, Ouellette AJ. Abundant androgen regulated mRNAs in mouse submandibular gland: Cell-free translation of renin precursor mRNA Nucleic Acids Research. 9: 3433-3449. PMID 6116224 DOI: 10.1093/nar/9.14.3433  0.96
1981 Ouellette AJ, Silverberg MB, Malt RA. Association of poly(adenylate)-deficient messenger ribonucleic acid with membranes in mouse kidney Biochemistry. 20: 3561-3567. PMID 6114742  0.96
1981 Ouellette AJ, Ordahl CP. Extensive homology between poly(A)-containing mRNA and purified nominal poly(A)-lacking mRNA in mouse kidney Journal of Biological Chemistry. 256: 5104-5108. PMID 6112224  0.96
1980 Ouellette AJ. Purification by benzoylated cellulose chromatography of translatable messenger ribonucleic acid lacking polyadenylate Journal of Biological Chemistry. 255: 2740-2746. PMID 7358705  0.96
1979 Ouellette AJ, Malt RA. Noncoordinate regulation of cytoplasmic RNA in compensatory renal hypertrophy The American Journal of Physiology. 237. PMID 495786  0.96
1978 Ouellette AJ. Messenger RNA in compensatory renal hypertrophy Yale Journal of Biology and Medicine. 51: 413-418. PMID 735161  0.96
1976 Ouellette AJ, Kumar A, Malt RA. Physical aspects and cytoplasmic distribution of messenger RNA in mouse kidney Bba Section Nucleic Acids and Protein Synthesis. 425: 384-395. PMID 1259978 DOI: 10.1016/0005-2787(76)90002-2  0.96
1976 Ouellette AJ, Reed SL, Malt RA. Short-lived methylated messenger RNA in mouse kidney. Proceedings of the National Academy of Sciences of the United States of America. 73: 2609-13. PMID 1066670  0.96
1976 Ouellette AJ, Bandman E, Kumar A. Regulation of ribosomal RNA methylation in a temperature-sensitive mutant of BHK cells Nature. 262: 619-621. PMID 958431 DOI: 10.1038/262619a0  0.96
1976 Ouellette AJ, Malt RA. Accumulation and decay of messenger ribonucleic acid in mouse kidney Biochemistry. 15: 3358-3361. PMID 952862  0.96
1975 Ouellette AJ, Frederick D, Malt RA. Methylated messenger RNA in mouse kidney. Biochemistry. 14: 4361-67. PMID 1174507  0.96
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