Peter Burkhard - Publications

Affiliations: 
Molecular and Cell Biology University of Connecticut, Storrs, CT, United States 
Area:
General Biophysics, Immunology, Biomedical Engineering

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 El Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Reed S, Estes A, Estes A, Lykins J, Burkhard P, McLeod R. Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice. Scientific Reports. 10: 16984. PMID 33046728 DOI: 10.1038/s41598-020-73210-0  0.32
2017 Kaba SA, Karch CP, Seth L, Ferlez KMB, Storme CK, Pesavento DM, Laughlin PY, Bergmann-Leitner ES, Burkhard P, Lanar DE. Self-assembling protein nanoparticles with built-in flagellin domains increases protective efficacy of a Plasmodium falciparum based vaccine. Vaccine. PMID 29269157 DOI: 10.1016/j.vaccine.2017.12.001  0.32
2017 El Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Roberts CW, Lanar DE, Reed S, Fox C, Carter D, Alexander J, Sette A, Sidney J, Lorenzi H, Begeman IJ, ... Burkhard P, et al. Protein nanovaccine confers robust immunity against Toxoplasma. Npj Vaccines. 2: 24. PMID 29263879 DOI: 10.1038/s41541-017-0024-6  0.32
2017 Karch CP, Doll TAPF, Paulillo SM, Nebie I, Lanar DE, Corradin G, Burkhard P. The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria. Journal of Nanobiotechnology. 15: 62. PMID 28877692 DOI: 10.1186/s12951-017-0295-0  0.32
2017 Seth L, Bingham Ferlez KM, Kaba SA, Musser DM, Emadi S, Matyas GR, Beck Z, Alving CR, Burkhard P, Lanar DE. Development of a self-assembling protein nanoparticle vaccine targeting Plasmodium falciparum Circumsporozoite Protein delivered in three Army Liposome Formulation adjuvants. Vaccine. PMID 28274638 DOI: 10.1016/j.vaccine.2017.02.040  0.32
2016 Karch CP, Li J, Kulangara C, Paulillo SM, Raman SK, Emadi S, Tan A, Helal ZH, Fan Q, Khan MI, Burkhard P. Vaccination with Self-Adjuvanted Protein Nanoparticles Provides Protection against Lethal Influenza Challenge. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27593488 DOI: 10.1016/j.nano.2016.08.030  0.32
2016 Karch CP, Burkhard P. Vaccine Technologies: From Whole Organisms to Rationally Designed Protein Assemblies. Biochemical Pharmacology. PMID 27157411 DOI: 10.1016/j.bcp.2016.05.001  0.44
2016 Indelicato G, Wahome N, Ringler P, Müller SA, Nieh MP, Burkhard P, Twarock R. Principles Governing the Self-Assembly of Coiled-Coil Protein Nanoparticles. Biophysical Journal. 110: 646-60. PMID 26840729 DOI: 10.1016/j.bpj.2015.10.057  0.44
2015 Doll TA, Dey R, Burkhard P. Design and optimization of peptide nanoparticles. Journal of Nanobiotechnology. 13: 73. PMID 26498651 DOI: 10.1186/s12951-015-0119-z  0.44
2015 Burkhard P, Lanar DE. Malaria vaccine based on self-assembling protein nanoparticles. Expert Review of Vaccines. 14: 1525-7. PMID 26468608 DOI: 10.1586/14760584.2015.1096781  0.44
2015 Doll TA, Neef T, Duong N, Lanar DE, Ringler P, Müller SA, Burkhard P. Optimizing the design of protein nanoparticles as carriers for vaccine applications. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26051652 DOI: 10.1016/j.nano.2015.05.003  0.44
2014 El Bissati K, Zhou Y, Dasgupta D, Cobb D, Dubey JP, Burkhard P, Lanar DE, McLeod R. Effectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic mice. Vaccine. 32: 3243-8. PMID 24736000 DOI: 10.1016/j.vaccine.2014.03.092  1
2013 Yang Y, Neef T, Mittelholzer C, Garcia Garayoa E, Bläuenstein P, Schibli R, Aebi U, Burkhard P. The biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platforms. Journal of Nanobiotechnology. 11: 36. PMID 24219600 DOI: 10.1186/1477-3155-11-36  1
2013 McCoy ME, Golden HE, Doll TA, Yang Y, Kaba SA, Zou X, Gerbasi VR, Burkhard P, Lanar DE. Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine. Malaria Journal. 12: 136. PMID 23607541 DOI: 10.1186/1475-2875-12-136  1
2013 Guo Q, Dasgupta D, Doll TA, Burkhard P, Lanar DE. Expression, purification and refolding of a self-assembling protein nanoparticle (SAPN) malaria vaccine. Methods (San Diego, Calif.). 60: 242-7. PMID 23548672 DOI: 10.1016/j.ymeth.2013.03.025  1
2013 Doll TA, Raman S, Dey R, Burkhard P. Nanoscale assemblies and their biomedical applications. Journal of the Royal Society, Interface / the Royal Society. 10: 20120740. PMID 23303217 DOI: 10.1098/rsif.2012.0740  1
2012 Kaba SA, McCoy ME, Doll TA, Brando C, Guo Q, Dasgupta D, Yang Y, Mittelholzer C, Spaccapelo R, Crisanti A, Burkhard P, Lanar DE. Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine. Plos One. 7: e48304. PMID 23144750 DOI: 10.1371/journal.pone.0048304  1
2012 Yang Y, Burkhard P. Encapsulation of gold nanoparticles into self-assembling protein nanoparticles. Journal of Nanobiotechnology. 10: 42. PMID 23114058 DOI: 10.1186/1477-3155-10-42  1
2012 Wahome N, Pfeiffer T, Ambiel I, Yang Y, Keppler OT, Bosch V, Burkhard P. Conformation-specific display of 4E10 and 2F5 epitopes on self-assembling protein nanoparticles as a potential HIV vaccine. Chemical Biology & Drug Design. 80: 349-57. PMID 22650354 DOI: 10.1111/j.1747-0285.2012.01423.x  1
2012 Yang Y, Ringler P, Müller SA, Burkhard P. Optimizing the refolding conditions of self-assembling polypeptide nanoparticles that serve as repetitive antigen display systems. Journal of Structural Biology. 177: 168-76. PMID 22115997 DOI: 10.1016/j.jsb.2011.11.011  0.44
2011 Maalouli N, Gouget-Laemmel AC, Pinchemel B, Bouazaoui M, Chazalviel JN, Ozanam F, Yang Y, Burkhard P, Boukherroub R, Szunerits S. Development of a metal-chelated plasmonic interface for the linking of His-peptides with a droplet-based surface plasmon resonance read-off scheme. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 5498-505. PMID 21480606 DOI: 10.1021/la2005437  1
2011 Kapinos LE, Burkhard P, Herrmann H, Aebi U, Strelkov SV. Simultaneous formation of right- and left-handed anti-parallel coiled-coil interfaces by a coil2 fragment of human lamin A. Journal of Molecular Biology. 408: 135-46. PMID 21354179 DOI: 10.1016/j.jmb.2011.02.037  0.44
2010 Meier M, Stetefeld J, Burkhard P. The many types of interhelical ionic interactions in coiled coils - an overview. Journal of Structural Biology. 170: 192-201. PMID 20211731 DOI: 10.1016/j.jsb.2010.03.003  0.44
2009 Kaba SA, Brando C, Guo Q, Mittelholzer C, Raman S, Tropel D, Aebi U, Burkhard P, Lanar DE. A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria. Journal of Immunology (Baltimore, Md. : 1950). 183: 7268-77. PMID 19915055 DOI: 10.4049/jimmunol.0901957  0.32
2009 Herrmann H, Strelkov SV, Burkhard P, Aebi U. Intermediate filaments: primary determinants of cell architecture and plasticity. The Journal of Clinical Investigation. 119: 1772-83. PMID 19587452 DOI: 10.1172/JCI38214  0.44
2009 Meier M, Padilla GP, Herrmann H, Wedig T, Hergt M, Patel TR, Stetefeld J, Aebi U, Burkhard P. Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. Journal of Molecular Biology. 390: 245-61. PMID 19422834 DOI: 10.1016/j.jmb.2009.04.067  0.44
2009 Pimentel TA, Yan Z, Jeffers SA, Holmes KV, Hodges RS, Burkhard P. Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chemical Biology & Drug Design. 73: 53-61. PMID 19152635 DOI: 10.1111/j.1747-0285.2008.00746.x  0.44
2007 Chattopadhyay A, Meier M, Ivaninskii S, Burkhard P, Speroni F, Campanini B, Bettati S, Mozzarelli A, Rabeh WM, Li L, Cook PF. Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes. Biochemistry. 46: 8315-30. PMID 17583914 DOI: 10.1021/bi602603c  0.44
2007 Parry DA, Strelkov SV, Burkhard P, Aebi U, Herrmann H. Towards a molecular description of intermediate filament structure and assembly. Experimental Cell Research. 313: 2204-16. PMID 17521629 DOI: 10.1016/j.yexcr.2007.04.009  0.44
2006 Raman S, Machaidze G, Lustig A, Aebi U, Burkhard P. Structure-based design of peptides that self-assemble into regular polyhedral nanoparticles. Nanomedicine : Nanotechnology, Biology, and Medicine. 2: 95-102. PMID 17292121 DOI: 10.1016/j.nano.2006.04.007  0.44
2006 Stetefeld J, Jenny M, Burkhard P. Intersubunit signaling in glutamate-1-semialdehyde-aminomutase Proceedings of the National Academy of Sciences of the United States of America. 103: 13688-13693. PMID 16954186 DOI: 10.1073/pnas.0600306103  0.44
2006 Meier M, Burkhard P. Statistical analysis of intrahelical ionic interactions in alpha-helices and coiled coils. Journal of Structural Biology. 155: 116-29. PMID 16876432 DOI: 10.1016/j.jsb.2006.02.019  0.44
2005 Appenzeller-Herzog C, Nyfeler B, Burkhard P, Santamaria I, Lopez-Otin C, Hauri HP. Carbohydrate- and conformation-dependent cargo capture for ER-exit. Molecular Biology of the Cell. 16: 1258-67. PMID 15635097 DOI: 10.1091/mbc.E04-08-0708  0.44
2005 Graff A, Tropel D, Roman SK, Machaidze G, Aebi U, Burkhard P. Peptidic nanoparticles: For cancer diagnosis and therapy Nanobiotechnology. 1: 293-294. DOI: 10.1385/Nano:1:3:293  1
2005 Graff A, Tropel D, Raman SK, Machaidze G, Lustig A, Burkhard P. Peptidic nanoparticles for cancer therapy and diagnosis 2005 Nsti Nanotechnology Conference and Trade Show - Nsti Nanotech 2005 Technical Proceedings. 112-115.  1
2005 Raman SK, Kao DJ, Tropel D, Graff A, Machaidze G, Hodges RS, Burkhard P. Peptide based nanoparticles as a platform for vaccine design 2005 Nsti Nanotechnology Conference and Trade Show - Nsti Nanotech 2005 Technical Proceedings. 47-50.  1
2004 Strelkov SV, Schumacher J, Burkhard P, Aebi U, Herrmann H. Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. Journal of Molecular Biology. 343: 1067-80. PMID 15476822 DOI: 10.1016/j.jmb.2004.08.093  0.44
2003 Lee DL, Ivaninskii S, Burkhard P, Hodges RS. Unique stabilizing interactions identified in the two-stranded alpha-helical coiled-coil: crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide. Protein Science : a Publication of the Protein Society. 12: 1395-405. PMID 12824486 DOI: 10.1110/ps.0241403  0.44
2003 Meier M, Oliveriusova J, Kraus JP, Burkhard P. Structural insights into mutations of cystathionine beta-synthase. Biochimica Et Biophysica Acta. 1647: 206-13. PMID 12686134 DOI: 10.1016/S1570-9639(03)00048-7  0.44
2002 Hahn E, Wild P, Hermanns U, Sebbel P, Glockshuber R, Häner M, Taschner N, Burkhard P, Aebi U, Müller SA. Exploring the 3D molecular architecture of Escherichia coli type 1 pili. Journal of Molecular Biology. 323: 845-57. PMID 12417198  0.44
2002 Smith TA, Strelkov SV, Burkhard P, Aebi U, Parry DA. Sequence comparisons of intermediate filament chains: evidence of a unique functional/structural role for coiled-coil segment 1A and linker L1. Journal of Structural Biology. 137: 128-45. PMID 12064940 DOI: 10.1006/jsbi.2002.4438  0.44
2002 Meier M, Lustig A, Aebi U, Burkhard P. Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide. Journal of Structural Biology. 137: 65-72. PMID 12064934 DOI: 10.1006/jsbi.2002.4467  0.44
2002 Strelkov SV, Burkhard P. Analysis of alpha-helical coiled coils with the program TWISTER reveals a structural mechanism for stutter compensation. Journal of Structural Biology. 137: 54-64. PMID 12064933 DOI: 10.1006/jsbi.2002.4454  0.44
2002 Burkhard P, Ivaninskii S, Lustig A. Improving coiled-coil stability by optimizing ionic interactions. Journal of Molecular Biology. 318: 901-10. PMID 12054832 DOI: 10.1016/S0022-2836(02)00114-6  0.44
2002 Strelkov SV, Herrmann H, Geisler N, Wedig T, Zimbelmann R, Aebi U, Burkhard P. Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. The Embo Journal. 21: 1255-66. PMID 11889032 DOI: 10.1093/emboj/21.6.1255  0.44
2001 Burkhard P, Dominici P, Borri-Voltattorni C, Jansonius JN, Malashkevich VN. Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nature Structural Biology. 8: 963-7. PMID 11685243 DOI: 10.1038/nsb1101-963  0.44
2001 Meier M, Janosik M, Kery V, Kraus JP, Burkhard P. Structure of human cystathionine β-synthase: A unique pyridoxal 5′-phosphate-dependent heme protein Embo Journal. 20: 3910-3916. PMID 11483494 DOI: 10.1093/emboj/20.15.3910  0.44
2001 De Marco V, Burkhard P, Le Bot N, Vernos I, Hoenger A. Analysis of heterodimer formation by Xklp3A/B, a newly cloned kinesin-II from Xenopus laevis Embo Journal. 20: 3370-3379. PMID 11432825 DOI: 10.1093/emboj/20.13.3370  0.44
2001 Tai CH, Burkhard P, Gani D, Jenn T, Johnson C, Cook PF. Characterization of the allosteric anion-binding site of O-acetylserine sulfhydrylase. Biochemistry. 40: 7446-52. PMID 11412097  0.44
2001 Janosik M, Meier M, Kery V, Oliveriusova J, Burkhard P, Kraus JP. Crystallization and preliminary X-ray diffraction analysis of the active core of human recombinant cystathionine β-synthase: An enzyme involved in vascular disease Acta Crystallographica Section D: Biological Crystallography. 57: 289-291. PMID 11173483 DOI: 10.1107/S0907444900017893  0.44
2001 Burkhard P, Stetefeld J, Strelkov SV. Coiled coils: A highly versatile protein folding motif Trends in Cell Biology. 11: 82-88. PMID 11166216 DOI: 10.1016/S0962-8924(00)01898-5  0.44
2001 Bruno S, Schiaretti F, Burkhard P, Kraus JP, Janosik M, Mozzarelli A. Functional properties of the active core of human cystathionine β-synthase crystals Journal of Biological Chemistry. 276: 16-19. PMID 11042162 DOI: 10.1074/jbc.C000588200  0.44
2000 Burkhard P, Meier M, Lustig A. Design of a minimal protein oligomerization domain by a structural approach Protein Science. 9: 2294-2301. PMID 11206050  0.44
2000 Von Matt A, Ehrhardt C, Burkhard P, Metternich R, Walkinshaw M, Tapparelli C. Selective boron-containing thrombin inhibitors - X-ray analysis reveals surprising binding mode Bioorganic and Medicinal Chemistry. 8: 2291-2303. PMID 11026541 DOI: 10.1016/S0968-0896(00)00147-4  0.44
2000 Burkhard P, Tai CH, Jansonius JN, Cook PF. Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound. Journal of Molecular Biology. 303: 279-86. PMID 11023792 DOI: 10.1006/jmbi.2000.4109  0.44
2000 Meier M, Bider MD, Malashkevich VN, Spiess M, Burkhard P. Crystal structure of the carbohydrate recognition domain of the H1 subunit of the asialoglycoprotein receptor. Journal of Molecular Biology. 300: 857-65. PMID 10891274 DOI: 10.1006/jmbi.2000.3853  0.44
2000 Burkhard P, Kammerer RA, Steinmetz MO, Bourenkov GP, Aebi U. The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges. Structure (London, England : 1993). 8: 223-30. PMID 10745004 DOI: 10.1016/S0969-2126(00)00100-3  0.44
2000 Burkhard P, Taylor P, Walkinshaw MD. X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies Journal of Molecular Biology. 295: 953-962. PMID 10656803 DOI: 10.1006/jmbi.1999.3411  0.44
1999 Burkhard P, Tai CH, Ristroph CM, Cook PF, Jansonius JN. Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium. Journal of Molecular Biology. 291: 941-53. PMID 10452898 DOI: 10.1006/jmbi.1999.3002  0.44
1999 Burkhard P, Hommel U, Sanner M, Walkinshaw MD. The discovery of steroids and other novel FKBP inhibitors using a molecular docking program Journal of Molecular Biology. 287: 853-858. PMID 10222195 DOI: 10.1006/jmbi.1999.2621  0.44
1999 Malashkevich VN, Burkhard P, Dominici P, Moore PS, Borri Voltattorni C, Jansonius JN. Preliminary X-ray analysis of a new crystal form of recombinant pig kidney DOPA decarboxylase. Acta Crystallographica. Section D, Biological Crystallography. 55: 568-70. PMID 10089382 DOI: 10.1107/S0907444998006283  0.44
1998 Burkhard P, Steinmetz MO, Schulthess T, Landwehr R, Aebi U, Kammerer RA. Crystallization and preliminary X-Ray diffraction analysis of the 190-A-long coiled-coil dimerization domain of the actin-bundling protein cortexillin I from dictyostelium discoideum Journal of Structural Biology. 122: 293-6. PMID 9774533 DOI: 10.1006/jsbi.1998.4005  0.44
1998 Mozzarelli A, Bettati S, Pucci AM, Burkhard P, Cook PF. Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry Journal of Molecular Biology. 283: 135-146. PMID 9761679 DOI: 10.1006/jmbi.1998.2038  0.44
1998 Burkhard P, Rao GS, Hohenester E, Schnackerz KD, Cook PF, Jansonius JN. Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium. Journal of Molecular Biology. 283: 121-33. PMID 9761678 DOI: 10.1006/JMBI.1998.2037  0.44
1998 Burkhard P, Taylor P, Walkinshaw MD. An example of a protein ligand found by database mining: Description of the docking method and its verification by a 2.3 Å X-ray structure of a thrombin-ligand complex Journal of Molecular Biology. 277: 449-466. PMID 9514757 DOI: 10.1006/jmbi.1997.1608  0.44
1996 Taylor P, Mikol V, Kallen J, Burkhard P, Walkinshaw MD. Conformational polymorphism in peptidic and nonpeptidic drug molecules Biopolymers - Peptide Science Section. 40: 585-592. PMID 9101762 DOI: 10.1002/(SICI)1097-0282(1996)40:5<585::AID-BIP16>3.0.CO;2-G  0.44
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