Phillip H. Pekala - Publications

Affiliations: 
Biochemistry and Molecular Biology East Carolina University, Greenville, NC, United States 
Area:
Biochemistry, Microbiology Biology

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Karschner VA, Pekala PH. HuR involvement in mitotic clonal expansion during acquisition of the adipocyte phenotype. Biochemical and Biophysical Research Communications. 383: 203-5. PMID 19345675 DOI: 10.1016/j.bbrc.2009.03.152  1
2008 Cherry J, Jones H, Karschner VA, Pekala PH. Post-transcriptional control of CCAAT/enhancer-binding protein beta (C/EBPbeta) expression: formation of a nuclear HuR-C/EBPbeta mRNA complex determines the amount of message reaching the cytosol. The Journal of Biological Chemistry. 283: 30812-20. PMID 18678862 DOI: 10.1074/jbc.M805659200  1
2007 Jones H, Carver M, Pekala PH. HuR binds to a single site on the C/EBPbeta mRNA of 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications. 355: 217-20. PMID 17288991 DOI: 10.1016/j.bbrc.2007.01.136  1
2006 Gantt KR, Cherry J, Richardson M, Karschner V, Atasoy U, Pekala PH. The regulation of glucose transporter (GLUT1) expression by the RNA binding protein HuR. Journal of Cellular Biochemistry. 99: 565-74. PMID 16639702 DOI: 10.1002/jcb.20950  1
2006 Cherry J, Karschner V, Jones H, Pekala PH. HuR, an RNA-binding protein, involved in the control of cellular differentiation. In Vivo (Athens, Greece). 20: 17-23. PMID 16433023  1
2005 Gantt K, Cherry J, Tenney R, Karschner V, Pekala PH. An early event in adipogenesis, the nuclear selection of the CCAAT enhancer-binding protein {beta} (C/EBP{beta}) mRNA by HuR and its translocation to the cytosol. The Journal of Biological Chemistry. 280: 24768-74. PMID 15863502 DOI: 10.1074/jbc.M502011200  1
2005 Tenney R, Stansfield K, Pekala PH. Interleukin 11 signaling in 3T3-L1 adipocytes. Journal of Cellular Physiology. 202: 160-6. PMID 15389536 DOI: 10.1002/jcp.20100  1
2004 Tenney R, Pekala PH. Interleukin 11 treatment alters the protein content of Galpha(i2) and adipogenic transcription factors in 3T3-L1 adipocytes. Cytokine. 27: 1-6. PMID 15207245 DOI: 10.1016/j.cyto.2004.03.008  1
2004 Gantt KR, Jain RG, Dudek RW, Pekala PH. HuB localizes to polysomes and alters C/EBP-beta expression in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications. 313: 619-22. PMID 14697236 DOI: 10.1016/j.bbrc.2003.11.162  1
2003 Tenney R, Turnbull JR, Stansfield KA, Pekala PH. The regulation of adipocyte metabolism and gene expression by interleukin-11. Advances in Enzyme Regulation. 43: 153-66. PMID 12791389 DOI: 10.1016/S0065-2571(02)00036-5  1
2002 Qi C, Wheeler JA, Pruett A, Pekala PH. Expression of the RNA binding proteins, Mel-N1, Mel-N2, and Mel-N3 in adipose cells. Biochemical and Biophysical Research Communications. 294: 329-33. PMID 12051715 DOI: 10.1016/S0006-291X(02)00472-2  1
2001 Qi C, Karkut C, Lombardi N, Pruett A, Tenney R, Wheeler J, Pekala PH. Adipocyte expression of a neuronal RNA-binding protein Advances in Enzyme Regulation. 41: 209-220. PMID 11384746 DOI: 10.1016/S0065-2571(00)00014-5  1
2000 Qi C, Pekala PH. Tumor necrosis factor-α-induced insulin resistance in adipocytes Proceedings of the Society For Experimental Biology and Medicine. 223: 128-135. PMID 10654615  1
1999 Qi C, Pekala PH. The influence of mRNA stability on glucose transporter (GLUT1) gene expression Biochemical and Biophysical Research Communications. 263: 265-269. PMID 10491282 DOI: 10.1006/bbrc.1999.1328  1
1999 Jain RC, Phelps KD, Pekala PH. Tumor necrosis factor-α initiated signal transduction in 3T3-L1 adipocytes Journal of Cellular Physiology. 179: 58-66. PMID 10082133 DOI: 10.1002/(SICI)1097-4652(199904)179:1<58::AID-JCP8>3.0.CO;2-1  1
1999 Jain R, Police S, Phelps K, Pekala PH. Tumour necrosis factor-α regulates expression of the CCAAT-enhancer-binding proteins (C/EBPs) α and β and determines the occupation of the C/EBP site in the promoter of the insulin-responsive glucose-transporter gene in 3T3-L1 adipocytes Biochemical Journal. 338: 737-743. PMID 10051447 DOI: 10.1042/0264-6021:3380737  1
1998 Jain RG, Meredith MJ, Pekala PH. Tumor necrosis factor-alpha mediated activation of signal transduction cascades and transcription factors in 3T3-L1 adipocytes. Advances in Enzyme Regulation. 38: 333-47. PMID 9762361 DOI: 10.1016/S0065-2571(97)00007-1  1
1998 Stewart WC, Pekala PH, Lieberman EM. Acute and chronic regulation of Na+/K+-ATPase transport activity in the RN22 Schwann cell line in response to stimulation of cyclic AMP production Glia. 23: 349-360. PMID 9671965 DOI: 10.1002/(SICI)1098-1136(199808)23:4<349::AID-GLIA7>3.0.CO;2-Y  1
1997 Jain RG, Andrews LG, McGowan KM, Pekala PH, Keene JD. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Molecular and Cellular Biology. 17: 954-62. PMID 9001249  1
1997 McGowan KM, Police S, Winslow JB, Pekala PH. Tumor necrosis factor-alpha regulation of glucose transporter (GLUT1) mRNA turnover. Contribution of the 3'-untranslated region of the GLUT1 message. The Journal of Biological Chemistry. 272: 1331-7. PMID 8995440 DOI: 10.1074/jbc.272.2.1331  1
1996 Long SD, Pekala PH. Lipid mediators of insulin resistance: Ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes Biochemical Journal. 319: 179-184. PMID 8870666  1
1996 McGowan K, Devente J, Carey JO, Ways DK, Pekala PH. Protein kinase C isoform expression during the differentiation of 3T3-L1 preadipocytes: Loss of protein kinase C-α isoform correlates with loss of phorbol 12-myristate 13-acetate activation of nuclear factor κB and acquisition of the adipocyte phenotype Journal of Cellular Physiology. 167: 113-120. PMID 8698828  1
1996 McGowan K, Pekala PH. Dehydrogenase binding to the 3′-untranslated region of GLUT1 mRNA Biochemical and Biophysical Research Communications. 221: 42-45. PMID 8660340 DOI: 10.1006/bbrc.1996.0541  1
1996 Long SD, Pekala PH. Regulation of GLUT4 mRNA stability by tumor necrosis factor-α: Alterations in both protein binding to the 3′ untranslated region and initiation of translation Biochemical and Biophysical Research Communications. 220: 949-953. PMID 8607873 DOI: 10.1006/bbrc.1996.0512  1
1996 Long SD, Pekala PH. Regulation of GLUT4 gene expression by arachidonic acid: Evidence for multiple pathways, one of which requires oxidation to prostaglandin E2 Journal of Biological Chemistry. 271: 1138-1144. PMID 8557642  1
1995 McGowan KM, Long SD, Pekala PH. Glucose transporter gene expression: Regulation of transcription and mRNA stability Pharmacology and Therapeutics. 66: 465-505. PMID 7494856 DOI: 10.1016/0163-7258(95)00007-4  1
1994 Tebbey PW, McGowan KM, Stephens JM, Buttke TM, Pekala PH. Arachidonic acid down-regulates the insulin-dependent glucose transporter gene (GLUT4) in 3T3-L1 adipocytes by inhibiting transcription and enhancing mRNA turnover Journal of Biological Chemistry. 269: 639-644. PMID 8276864  1
1994 Spolarics Z, Bagby GJ, Pekala PH, Dobrescu C, Skrepnik N, Spitzer JJ. Acute alcohol administration attenuates insulin-mediated glucose use by skeletal muscle Am.J.Physiol.. 267.  1
1993 Endo H, Sabri MI, Stephens JM, Pekala PH, Kittur S. Acrylamide induces immediate-early gene expression in rat brain. Brain Research. 609: 231-6. PMID 8508307 DOI: 10.1016/0006-8993(93)90877-P  1
1993 Spolarics Z, Pekala PH, Bagby GJ, Spitzer JJ. Brief Endotoxemia Markedly Increases Expression of Glut1 Glucose Transporter in Kupffer, Hepatic Endothelial and Parenchymal Cells Biochemical and Biophysical Research Communications. 193: 1211-1215. PMID 8323543 DOI: 10.1006/bbrc.1993.1754  1
1993 Stephens JM, Butts M, Stone R, Pekala PH, Bernlohr DA. Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis Molecular and Cellular Biochemistry. 123: 63-71. PMID 7694071 DOI: 10.1007/BF01076476  1
1992 Stephens JM, Pekala PH. Transcriptional repression of the C/EBP-α and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-α: Regulation is coordinate and independent of protein synthesis Journal of Biological Chemistry. 267: 13580-13584. PMID 1618860  1
1992 Stephens JM, Bagby GJ, Pekala PH, Shepherd RE, Spitzer JJ, Lang CH. Differential regulation of glucose transporter gene expression in adipose tissue of septic rats Biochemical and Biophysical Research Communications. 183: 417-422. PMID 1550551 DOI: 10.1016/0006-291X(92)90497-9  1
1992 Stephens JM, Butts MD, Pekala PH. Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by tumour necrosis factor-α Journal of Molecular Endocrinology. 9: 61-72. PMID 1515026  1
1992 song L, Stephens JM, Kittur S, Collins GD, Nagel JE, Pekala PH, Adler WH. Expression of c-fos, c-jun and jun B in peripheral blood lymphocytes from young and elderly adults Mechanisms of Ageing and Development. 65: 149-156. PMID 1434944 DOI: 10.1016/0047-6374(92)90031-8  1
1992 Stephens JM, Carter BZ, Pekala PH, Malter JS. Tumor necrosis factor α-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes: Regulation by the adenosine-uridine binding factor Journal of Biological Chemistry. 267: 8336-8341. PMID 1314824  1
1991 Cornelius P, Marlowe M, Call K, Pekala PH. Regulation of glucose transport as well as glucose transporter and immediate early gene expression in 3T3-L1 preadipocytes by 8-bromo-cAMP. Journal of Cellular Physiology. 146: 298-308. PMID 1999478 DOI: 10.1002/jcp.1041460215  1
1991 Stephens JM, Pekala PH. Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-α Journal of Biological Chemistry. 266: 21839-21845. PMID 1939208  1
1990 Kern M, Wells JA, Stephens JM, Elton CW, Friedman JE, Tapscott EB, Pekala PH, Dohm GL. Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level. The Biochemical Journal. 270: 397-400. PMID 2205203  1
1990 Cornelius P, Marlowe M, Pekala PH. Regulation of glucose transport by tumor necrosis factor-alpha in cultured murine 3T3-L1 fibroblasts. The Journal of Trauma. 30: S15-20. PMID 2123942  1
1990 Ginty DD, Marlowe M, Pekala PH, Seidel ER. Multiple pathways for the regulation of ornithine decarboxylase in intestinal epithelial cells. The American Journal of Physiology. 258: G454-60. PMID 2107756  1
1990 Cornelius P, Marlowe M, Lee MD, Pekala PH. The growth factor-like effects of tumor necrosis factor-alpha. Stimulation of glucose transport activity and induction of glucose transporter and immediate early gene expression in 3T3-L1 preadipocytes. The Journal of Biological Chemistry. 265: 20506-16. PMID 1700789  1
1989 Kaestner KH, Christy RJ, McLenithan JC, Braiterman LT, Cornelius P, Pekala PH, Lane MD. Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes Proceedings of the National Academy of Sciences of the United States of America. 86: 3150-3154. PMID 2654938  1
1989 Cornelius P, Lee MD, Marlowe M, Pekala PH. Monokine regulation of glucose transporter mRNA in L6 myotubes. Biochemical and Biophysical Research Communications. 165: 429-36. PMID 2556143 DOI: 10.1016/0006-291X(89)91088-7  1
1988 Cornelius P, Enerback S, Bjursell G, Olivecrona T, Pekala PH. Regulation of lipoprotein lipase mRNA content in 3T3-L1 cells by tumour necrosis factor Biochemical Journal. 249: 765-769. PMID 3355496  1
1988 Knupp C, Pekala PH, Cornelius P. Extensive bone marrow necrosis in patients with cancer and tumor necrosis factor activity in plasma American Journal of Hematology. 29: 215-221. PMID 3189318  1
1988 Eades DK, Cornelius P, Pekala PH. Characterization of the tumour necrosis factor receptor in human placenta Placenta. 9: 247-251. PMID 2845388 DOI: 10.1016/0143-4004(88)90032-X  1
1987 Lee MD, Zentella A, Vine W, Pekala PH, Cerami A. Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6. Proceedings of the National Academy of Sciences of the United States of America. 84: 2590-4. PMID 3472226  1
1986 Price SR, Olivecrona T, Pekala PH. Regulation of lipoprotein lipase synthesis in 3T3-L1 adipocytes by cachectin. Further proof for identity with tumour necrosis factor Biochemical Journal. 240: 601-604. PMID 3814100  1
1986 Price SR, Olivecrona T, Pekala PH. Regulation of lipoprotein lipase synthesis by recombinant tumor necrosis factor-The primary regulatory role of the hormone in 3T3-L1 adipocytes Archives of Biochemistry and Biophysics. 251: 738-746. PMID 3800396 DOI: 10.1016/0003-9861(86)90384-X  1
1986 Garris DR, West RL, Pekala PH. Ultrastructural and metabolic changes associated with reproductive tract atrophy and adiposity in diabetic female mice. The Anatomical Record. 216: 359-66. PMID 3789418 DOI: 10.1002/ar.1092160304  1
1986 Price SR, Mizel SB, Pekala PH. Regulation of lipoprotein lipase synthesis and 3T3-L1 adipocyte metabolism by recombinant interleukin 1 Bba - Molecular Cell Research. 889: 374-381. PMID 3491626 DOI: 10.1016/0167-4889(86)90201-6  1
1985 Price SR, Bautista A, Volkman A, Pekala PH. Regulation of 3T3-L1 lipoprotein lipase by an endotoxin-induced family of macrophage secretory proteins, one of which has a potent interleukin (IL1)-like activity Federation Proceedings. 44.  1
1984 Pekala PH, Price SR, Horn CA, Hom BE, Moss J, Cerami A. Model for cachexia in chronic disease: secretory products of endotoxin-stimulated macrophages induce a catabolic state in 3T3-L1 adipocytes. Transactions of the Association of American Physicians. 97: 251-9. PMID 6100150  1
1983 Pekala PH, Moss J. Poly ADP-ribosylation of protein Current Topics in Cellular Regulation. 22: 1-49. PMID 6409509  1
1983 Pekala PH, Moss J. 3T3-L1 preadipocyte differentiation and poly(ADP-ribose) synthetase Molecular and Cellular Biochemistry. 53: 221-232. PMID 6194420 DOI: 10.1007/BF00225255  1
1983 Pekala PH, Kawakami M, Angus CW, Lane MD, Cerami A. Selective inhibition of synthesis of enzymes for de novo fatty acid biosynthesis by an endotoxin-induced mediator from exudate cells Proceedings of the National Academy of Sciences of the United States of America. 80: 2743-2747. PMID 6133282  1
1982 Kawakami M, Pekala PH, Lane MD, Cerami A. Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells Proceedings of the National Academy of Sciences of the United States of America. 79: 912-916. PMID 7038689  1
1982 Watkins PA, Moss J, Pekala PH, Lane MD. Effect of differentiation on the adenylate cyclase system of 3T3-C2 and 3T3-L1 cells. Determination of choleragen substrates in differentiating 3T3-L1 and nondifferentiating 3T3-C2 cells Journal of Biological Chemistry. 257: 14719-14722. PMID 6294075  1
1981 Pekala PH, Lane MD, Watkins PA, Moss J. On the mechanism of preadipocyte differentiation. Masking of poly(ADP-ribose) synthetase activity during differentiation of 3T3-L1 preadipocytes Journal of Biological Chemistry. 256: 4871-4876. PMID 6164677  1
1981 Pekala PH, Lane MD. Independent effects of differentiating conditions and time in culture on hormone responsiveness and guanine nucleotide regulatory proteins of 3T3-L1 preadipocytes and 3T3-C2 fibroblasts Journal of Cell Biology. 91.  1
1980 Pekala PH, Yost DA, Anderson BM. Self-inactivation of an erythrocyte NAD glycohydrolase Molecular and Cellular Biochemistry. 31: 49-56. PMID 6248764 DOI: 10.1007/BF00817890  1
1978 Pekala PH, Anderson BM. Studies of bovine erythrocyte NAD glycohydrolase Journal of Biological Chemistry. 253: 7453-7459. PMID 212424  1
1978 Pekala PH, Meredith MJ, Tarlow DM, Lane MD. Multiple phosphorylation of acetyl-CoA carboxylase in chick liver cells. A cyclic AMP-independent process Journal of Biological Chemistry. 253: 5267-5269. PMID 27515  1
1975 Pekala PH, Perfetti T, Hartline RA. Physiological basis for preferential uptake of d-α-aminoadipate over the l-isomer by Alcaligenes denitrificans Bba - Biomembranes. 394: 65-75. PMID 1138928 DOI: 10.1016/0005-2736(75)90205-9  1
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