Year |
Citation |
Score |
2023 |
Kong X, Yan W, Sun W, Zhang Y, Yang HJ, Chen M, Chen H, de Vere White RW, Zhang J, Chen X. Isoform-specific disruption of the gene reveals a critical role for TAp73γ in tumorigenesis via leptin. Elife. 12. PMID 37650871 DOI: 10.7554/eLife.82115 |
0.325 |
|
2023 |
Zou H, Yang Y, Chen HW. Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner. Frontiers in Pharmacology. 14: 1146741. PMID 37180705 DOI: 10.3389/fphar.2023.1146741 |
0.398 |
|
2022 |
Ning S, Zhao J, Lombard AP, D'Abronzo LS, Leslie AR, Sharifi M, Lou W, Liu C, Yang JC, Evans CP, Corey E, Chen HW, Yu A, Ghosh PM, Gao AC. Activation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes. Communications Medicine. 2: 118. PMID 36159187 DOI: 10.1038/s43856-022-00182-9 |
0.303 |
|
2022 |
Yang N, Yang Y, Huang Z, Chen HW. Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer. Cancers. 14. PMID 35804882 DOI: 10.3390/cancers14133110 |
0.301 |
|
2022 |
Zou H, Yang Y, Shi Z, Wu X, Liu R, Yu AM, Chen HW. Nuclear receptor RORγ inverse agonists/antagonists display tissue- and gene-context selectivity through distinct activities in altering chromatin accessibility and master regulator SREBP2 occupancy. Pharmacological Research. 182: 106324. PMID 35750301 DOI: 10.1016/j.phrs.2022.106324 |
0.3 |
|
2021 |
Wang H, Wang Q, Cai G, Duan Z, Nugent Z, Huang J, Zheng J, Borowsky AD, Li JJ, Liu P, Kung HJ, Murphy L, Chen HW, Wang J. Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop NRF2 in cancer therapeutic resistance. Acta Pharmaceutica Sinica. B. 12: 1871-1884. PMID 35847493 DOI: 10.1016/j.apsb.2021.10.015 |
0.338 |
|
2021 |
Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, Li CF, Wang LH, Chen HW, Yen Y, Ann DK, et al. Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes. Theranostics. 11: 7527-7545. PMID 34158865 DOI: 10.7150/thno.54695 |
0.308 |
|
2021 |
Zhang X, Huang Z, Wang J, Ma Z, Yang J, Corey E, Evans CP, Yu AM, Chen HW. Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling. Cancers. 13. PMID 33916325 DOI: 10.3390/cancers13071672 |
0.37 |
|
2020 |
Zheng J, Wang J, Wang Q, Zou H, Wang H, Zhang Z, Chen J, Wang Q, Wang P, Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, ... Chen HW, et al. Targeting castration-resistant prostate cancer with a novel ROR antagonist elaiophylin. Acta Pharmaceutica Sinica. B. 10: 2313-2322. PMID 33354503 DOI: 10.1016/J.Apsb.2020.07.001 |
0.482 |
|
2020 |
Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, ... ... Chen HW, et al. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nature Communications. 11: 4591. PMID 32929084 DOI: 10.1038/S41467-020-18245-7 |
0.381 |
|
2020 |
Wang Q, Zheng J, Zou JX, Xu J, Han F, Xiang S, Liu P, Chen HW, Wang J. S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis. Chemico-Biological Interactions. 108965. PMID 32001260 DOI: 10.1016/j.cbi.2020.108965 |
0.317 |
|
2019 |
Duan Z, Andrews NP, Chen CZ, Fan M, Wang J, Shen J, Li JJ, Chen HW. Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation. Oncology Reports. PMID 31789405 DOI: 10.3892/Or.2019.7418 |
0.366 |
|
2019 |
Wang Y, Huang Z, Chen CZ, Liu C, Evans CP, Gao AC, Zhou F, Chen HW. Therapeutic targeting MDR1 expression by RORγ antagonists resensitizes cross-resistant CRPC to taxane via coordinated induction of cell death programs. Molecular Cancer Therapeutics. PMID 31712394 DOI: 10.1158/1535-7163.MCT-19-0327 |
0.31 |
|
2019 |
Lombard AP, Liu C, Armstrong CM, D'Abronzo LS, Lou W, Chen H, Dall'Era M, Ghosh PM, Evans CP, Gao AC. Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer. Translational Oncology. 12: 871-878. PMID 31075528 DOI: 10.1016/J.Tranon.2019.04.007 |
0.36 |
|
2019 |
Zhang Y, Wu X, Xue X, Li C, Wang J, Wang R, Zhang C, Wang C, Shi Y, Zou L, Li Q, Huang Z, Hao X, Loomes KM, Wu D, ... Chen H, et al. Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer (CRPC). Journal of Medicinal Chemistry. PMID 30964293 DOI: 10.1021/Acs.Jmedchem.9B00327 |
0.43 |
|
2019 |
Wang JJ, Zou JX, Wang H, Duan ZJ, Wang HB, Chen P, Liu PQ, Xu JZ, Chen HW. Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling. Acta Pharmacologica Sinica. PMID 30670815 DOI: 10.1038/S41401-018-0199-Z |
0.435 |
|
2019 |
Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel OD, Tepper CG, Chen H, Dall’Era M, Evans CP, Gao AC. Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone Cancer Research. 79: 334-334. DOI: 10.1158/1538-7445.Am2019-334 |
0.455 |
|
2019 |
Liu* C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel OD, Tepper CG, Dall’Era M, Chen H, Evans CP, Gao AC. MP22-08 PROTEOSTASIS BY HSP70/STUB1 COMPLEX REGULATES ANDROGEN RECEPTOR VARIANTS EXPRESSION AND CONFERS RESISTANCE TO ENZALUTAMIDE AND ABIRATERONE Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555593.31745.C3 |
0.437 |
|
2018 |
Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel ODV, Tepper CG, Chen HW, Dall'Era M, Evans CP, Gao AC. Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer. Nature Communications. 9: 4700. PMID 30446660 DOI: 10.1038/S41467-018-07178-X |
0.424 |
|
2018 |
Wang HJ, Pochampalli M, Wang LY, Zou JX, Li PS, Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, ... ... Chen HW, et al. KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene. PMID 30072740 DOI: 10.1038/S41388-018-0414-X |
0.374 |
|
2018 |
Xue X, Zhang Y, Wang C, Zhang M, Xiang Q, Wang J, Wang A, Li C, Zhang C, Zou L, Wang R, Wu S, Lu Y, Chen H, Ding K, et al. Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer. European Journal of Medicinal Chemistry. 152: 542-559. PMID 29758518 DOI: 10.1016/J.Ejmech.2018.04.034 |
0.408 |
|
2018 |
Zhang M, Zhang Y, Song M, Xue X, Wang J, Wang C, Zhang C, Li C, Xiang Q, Zou L, Wu X, Wu C, Dong B, Xue W, Zhou Y, ... Chen H, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). Journal of Medicinal Chemistry. PMID 29566488 DOI: 10.1021/Acs.Jmedchem.8B00103 |
0.371 |
|
2017 |
Candas D, Zhang L, Menaa C, Fan M, Zhang Y, Liu L, Zhou W, Azghadi S, Sweeney C, Shen R, Lin T, Pan C, Vaughan AT, Wang JM, Chen H, et al. Abstract LB-226: Dual inhibition of CD47 and HER2 to radiosensitize breast cancer cells Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-226 |
0.355 |
|
2016 |
Wang J, Wang H, Wang LY, Cai D, Duan Z, Zhang Y, Chen P, Zou JX, Xu J, Chen X, Kung HJ, Chen HW. Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy. Cell Death and Differentiation. PMID 27612013 DOI: 10.1038/Cdd.2016.92 |
0.335 |
|
2016 |
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, ... ... Chen HW, et al. Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. 22: 692. PMID 27270780 DOI: 10.1038/Nm0616-692B |
0.668 |
|
2016 |
Chen P, Wang H, Yang F, Chen H, He W, Wang J. Curcumin Promotes Osteosarcoma Cell Death by Activating miR-125a/ERRα Signal Pathway. Journal of Cellular Biochemistry. PMID 27231954 DOI: 10.1002/Jcb.25612 |
0.369 |
|
2016 |
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, ... ... Chen HW, et al. ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. PMID 27019329 DOI: 10.1038/Nm.4070 |
0.682 |
|
2016 |
Wang J, Wang H, Wang L, Cai D, Duan Z, Chen P, Zou JX, Xu J, Chen X, Kung H, Chen H. Abstract 3062: Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy Cancer Research. 76: 3062-3062. DOI: 10.1158/1538-7445.Am2016-3062 |
0.448 |
|
2015 |
Krakstad C, Tangen IL, Hoivik EA, Halle MK, Berg A, Werner HM, Ræder MB, Kusonmano K, Zou JX, Øyan AM, Stefansson I, Trovik J, Kalland KH, Chen HW, Salvesen HB. ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma. Oncotarget. 6: 28440-52. PMID 26308378 DOI: 10.18632/Oncotarget.4955 |
0.387 |
|
2015 |
Wang Y, Stokes A, Duan Z, Hui J, Xu Y, Chen Y, Chen HW, Lam K, Zhou CJ. LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia. Journal of the American Society of Nephrology : Jasn. PMID 26047795 DOI: 10.1681/Asn.2014100998 |
0.305 |
|
2015 |
Huang X, Zhang S, Qi H, Wang Z, Chen HW, Shao J, Shen J. JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation. Biochimica Et Biophysica Acta. PMID 26025680 DOI: 10.1016/J.Bbamcr.2015.05.026 |
0.418 |
|
2015 |
Wang L, Hung C, Yu Y, Chen H, Srivastava S, Petrovics G, Kung H. Abstract B16: A novel long non-coding RNA connects c-Myc to tumor metabolism Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B16 |
0.429 |
|
2014 |
Hung CL, Wang LY, Yu YL, Chen HW, Srivastava S, Petrovics G, Kung HJ. A long noncoding RNA connects c-Myc to tumor metabolism. Proceedings of the National Academy of Sciences of the United States of America. 111: 18697-702. PMID 25512540 DOI: 10.1073/pnas.1415669112 |
0.328 |
|
2014 |
Chen P, Wang H, Duan Z, Zou JX, Chen H, He W, Wang J. Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. Biomed Research International. 2014: 616025. PMID 24967384 DOI: 10.1155/2014/616025 |
0.373 |
|
2014 |
Zou JX, Duan Z, Wang J, Sokolov A, Xu J, Chen CZ, Li JJ, Chen HW. Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance. Molecular Cancer Research : McR. 12: 539-49. PMID 24391143 DOI: 10.1158/1541-7786.Mcr-13-0459 |
0.478 |
|
2014 |
Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ. Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells (Dayton, Ohio). 32: 45-58. PMID 24115331 DOI: 10.1002/Stem.1561 |
0.302 |
|
2014 |
Krakstad C, Tangen IL, Raeder MB, Hoivik E, Kusonmano K, Zou JX, Øyan AM, Trovik J, Chen H, Kalland KH, Salvesen HB. Abstract 2875: ATAD2 overexpression indentifies aggressive endometrial carcinomas Cancer Research. 74: 2875-2875. DOI: 10.1158/1538-7445.Am2014-2875 |
0.378 |
|
2014 |
Zou JX, Wang J, Duan Z, Chen H, Kung H, Chen X, Murphy LC, Borowsky A. Abstract 2433: Metabolic reprogramming by an epigenetic mechanism in endocrine therapy resistance of breast cancer Cancer Research. 74: 2433-2433. DOI: 10.1158/1538-7445.Am2014-2433 |
0.428 |
|
2013 |
Tummala R, Nadiminty N, Lou W, Zhu Y, Gandour-Edwards R, Chen HW, Evans CP, Gao AC. Lin28 promotes growth of prostate cancer cells and activates the androgen receptor. The American Journal of Pathology. 183: 288-95. PMID 23790802 DOI: 10.1016/J.Ajpath.2013.03.011 |
0.468 |
|
2013 |
Chen NT, Kuwabara Y, Conley C, Liao YC, Hong SY, Chen M, Shih YP, Chen HW, Hsieh F, Lo SH. Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene. Gene. 520: 90-7. PMID 23500447 DOI: 10.1016/J.Gene.2013.02.041 |
0.39 |
|
2013 |
Duan Z, Zou JX, Yang P, Wang Y, Borowsky AD, Gao AC, Chen HW. Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex. The Prostate. 73: 455-66. PMID 23038103 DOI: 10.1002/Pros.22587 |
0.403 |
|
2012 |
Berger CE, Qian Y, Liu G, Chen H, Chen X. p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells. The Journal of Biological Chemistry. 287: 30117-27. PMID 22787161 DOI: 10.1074/Jbc.M112.367326 |
0.416 |
|
2012 |
Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X, Kung HJ, Gao AC, Zou JX, Chen HW. Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Molecular and Cellular Biology. 32: 3121-31. PMID 22645312 DOI: 10.1128/Mcb.00204-12 |
0.41 |
|
2012 |
Nadiminty N, Tummala R, Lou W, Zhu Y, Shi XB, Zou JX, Chen H, Zhang J, Chen X, Luo J, deVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. Plos One. 7: e32832. PMID 22479342 DOI: 10.1371/Journal.Pone.0032832 |
0.394 |
|
2011 |
Zhang J, Cho SJ, Shu L, Yan W, Guerrero T, Kent M, Skorupski K, Chen H, Chen X. Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes & Development. 25: 1528-43. PMID 21764855 DOI: 10.1101/Gad.2069311 |
0.306 |
|
2010 |
Hsia EY, Goodson ML, Zou JX, Privalsky ML, Chen HW. Nuclear receptor coregulators as a new paradigm for therapeutic targeting. Advanced Drug Delivery Reviews. 62: 1227-37. PMID 20933027 DOI: 10.1016/J.Addr.2010.09.016 |
0.384 |
|
2010 |
Kalashnikova EV, Revenko AS, Gemo AT, Andrews NP, Tepper CG, Zou JX, Cardiff RD, Borowsky AD, Chen HW. ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2. Cancer Research. 70: 9402-12. PMID 20864510 DOI: 10.1158/0008-5472.Can-10-1199 |
0.649 |
|
2010 |
Revenko AS, Kalashnikova EV, Gemo AT, Zou JX, Chen HW. Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Molecular and Cellular Biology. 30: 5260-72. PMID 20855524 DOI: 10.1128/Mcb.00484-10 |
0.662 |
|
2010 |
Hsia EY, Kalashnikova EV, Revenko AS, Zou JX, Borowsky AD, Chen HW. Deregulated E2F and the AAA+ coregulator ANCCA drive proto-oncogene ACTR/AIB1 overexpression in breast cancer. Molecular Cancer Research : McR. 8: 183-93. PMID 20124470 DOI: 10.1158/1541-7786.Mcr-09-0095 |
0.648 |
|
2009 |
Hsia EYC, Zou JX, Chen HW. Chapter 8 The Roles and Action Mechanisms of p160/SRC Coactivators and the ANCCA Coregulator in Cancer Progress in Molecular Biology and Translational Science. 87: 261-298. PMID 20374707 DOI: 10.1016/S1877-1173(09)87008-7 |
0.489 |
|
2009 |
Qin L, Liu Z, Chen H, Xu J. The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Research. 69: 3819-27. PMID 19383905 DOI: 10.1158/0008-5472.Can-08-4389 |
0.453 |
|
2009 |
Zou JX, Guo L, Revenko AS, Tepper CG, Gemo AT, Kung HJ, Chen HW. Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Research. 69: 3339-46. PMID 19318566 DOI: 10.1158/0008-5472.CAN-08-3440 |
0.386 |
|
2008 |
Shi XB, Xue L, Zou JX, Gandour-Edwards R, Chen H, deVere White RW. Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells. The Prostate. 68: 1816-26. PMID 18780293 DOI: 10.1002/Pros.20849 |
0.442 |
|
2008 |
Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and Cellular Biology. 28: 5937-50. PMID 18644862 DOI: 10.1128/Mcb.00579-08 |
0.363 |
|
2008 |
Li LB, Louie MC, Chen HW, Zou JX. Proto-oncogene ACTR/AIB1 promotes cancer cell invasion by up-regulating specific matrix metalloproteinase expression. Cancer Letters. 261: 64-73. PMID 18162290 DOI: 10.1016/J.Canlet.2007.11.013 |
0.659 |
|
2007 |
Zou JX, Revenko AS, Li LB, Gemo AT, Chen HW. ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification. Proceedings of the National Academy of Sciences of the United States of America. 104: 18067-72. PMID 17998543 DOI: 10.1073/Pnas.0705814104 |
0.444 |
|
2006 |
Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ. Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Research. 66: 10449-59. PMID 17079466 DOI: 10.1158/0008-5472.Can-06-2582 |
0.309 |
|
2006 |
Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ. Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Cancer Research. 66: 8439-47. PMID 16951154 DOI: 10.1158/0008-5472.Can-06-1636 |
0.444 |
|
2006 |
Zou JX, Zhong Z, Shi XB, Tepper CG, deVere White RW, Kung HJ, Chen H. ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes. The Prostate. 66: 1474-86. PMID 16921507 DOI: 10.1002/Pros.20477 |
0.498 |
|
2006 |
Louie MC, Revenko AS, Zou JX, Yao J, Chen HW. Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity. Molecular and Cellular Biology. 26: 3810-23. PMID 16648476 DOI: 10.1128/Mcb.26.10.3810-3823.2006 |
0.697 |
|
2004 |
Louie MC, Zou JX, Rabinovich A, Chen HW. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Molecular and Cellular Biology. 24: 5157-71. PMID 15169882 DOI: 10.1128/Mcb.24.12.5157-5171.2004 |
0.712 |
|
2004 |
Lee LF, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, Kung HJ. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene. 23: 2197-205. PMID 14767470 DOI: 10.1038/Sj.Onc.1207344 |
0.647 |
|
2003 |
Louie MC, Yang HQ, Ma AH, Xu W, Zou JX, Kung HJ, Chen HW. Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex. Proceedings of the National Academy of Sciences of the United States of America. 100: 2226-30. PMID 12589022 DOI: 10.1073/Pnas.0437824100 |
0.65 |
|
2002 |
Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature. 415: 549-53. PMID 11823864 DOI: 10.1038/415549A |
0.409 |
|
2001 |
Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961 |
0.317 |
|
2001 |
Chen H, Tini M, Evans RM. HATs on and beyond chromatin. Current Opinion in Cell Biology. 13: 218-24. PMID 11248556 DOI: 10.1016/S0955-0674(00)00200-3 |
0.312 |
|
1999 |
Chen H, Lin RJ, Xie W, Wilpitz D, Evans RM. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell. 98: 675-86. PMID 10490106 DOI: 10.1016/S0092-8674(00)80054-9 |
0.39 |
|
1999 |
Chakravarti D, Ogryzko V, Kao HY, Nash A, Chen H, Nakatani Y, Evans RM. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell. 96: 393-403. PMID 10025405 DOI: 10.1016/S0092-8674(00)80552-8 |
0.339 |
|
1998 |
Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, Evans RM, Nakatani Y, Ozato K. The histone acetylase PCAF is a nuclear receptor coactivator. Genes & Development. 12: 1638-51. PMID 9620851 DOI: 10.1101/Gad.12.11.1638 |
0.373 |
|
1998 |
Blumberg B, Kang H, Bolado J, Chen H, Craig AG, Moreno TA, Umesono K, Perlmann T, De Robertis EM, Evans RM. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes & Development. 12: 1269-77. PMID 9573044 DOI: 10.1101/Gad.12.9.1269 |
0.336 |
|
1998 |
Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93: 229-40. PMID 9568715 DOI: 10.1016/S0092-8674(00)81574-3 |
0.344 |
|
1997 |
Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4 |
0.37 |
|
1997 |
Chen HW, Privalsky ML. Retinoid X and retinoic acid receptors interact with transcription factor II-B by distinct mechanisms Molecular and Cellular Endocrinology. 129: 55-61. PMID 9175629 DOI: 10.1016/S0303-7207(97)04040-9 |
0.371 |
|
1997 |
Lin BC, Wong CW, Chen HW, Privalsky ML. Plasticity of tetramer formation by retinoid X receptors. An alternative paradigm for DNA recognition. The Journal of Biological Chemistry. 272: 9860-7. PMID 9092522 DOI: 10.1074/Jbc.272.15.9860 |
0.33 |
|
1995 |
Chen H, Privalsky ML. Cooperative formation of high-order oligomers by retinoid X receptors: An unexpected mode of DNA recognition Proceedings of the National Academy of Sciences of the United States of America. 92: 422-426. PMID 7831303 DOI: 10.1073/Pnas.92.2.422 |
0.372 |
|
1993 |
Chen HW, Privalsky ML. The erbA oncogene represses the actions of both retinoid X and retinoid A receptors but does so by distinct mechanisms Molecular and Cellular Biology. 13: 5970-5980. PMID 8105369 DOI: 10.1128/Mcb.13.10.5970 |
0.371 |
|
1993 |
Chen H, Smit-Mcbride Z, Lewis S, Sharif M, Privalsky ML. Nuclear hormone receptors involved in neoplasia: Erb A exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domain Molecular and Cellular Biology. 13: 2366-2376. PMID 8096060 DOI: 10.1128/Mcb.13.4.2366 |
0.37 |
|
1993 |
Sande S, Sharif M, Chen H, Privalsky M. v-erbA acts on retinoic acid receptors in immature avian erythroid cells. Journal of Virology. 67: 1067-74. PMID 8093487 DOI: 10.1128/Jvi.67.2.1067-1074.1993 |
0.376 |
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