Philip W. Majerus, M.D. - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
https://hematology.im.wustl.edu/people/faculty/Majerus_P/Majerus_P_Bio.html

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Zou J, Zhang C, Marjanovic J, Kisseleva MV, Majerus PW, Wilson MP. Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8. Proceedings of the National Academy of Sciences of the United States of America. 109: 9539-44. PMID 22647598 DOI: 10.1073/Pnas.1207021109  0.773
2012 Zhang C, Majerus PW, Wilson MP. Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 2290-5. PMID 22308441 DOI: 10.1073/Pnas.1119740109  0.411
2012 Zou J, Majerus PW, Wilson DB, Schrade A, Chang SC, Wilson MP. The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. Advances in Biological Regulation. 52: 282-9. PMID 22056831 DOI: 10.1016/J.Advenzreg.2011.10.001  0.349
2011 Ferron M, Boudiffa M, Arsenault M, Rached M, Pata M, Giroux S, Elfassihi L, Kisseleva M, Majerus PW, Rousseau F, Vacher J. Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans. Cell Metabolism. 14: 466-77. PMID 21982707 DOI: 10.1016/J.Cmet.2011.08.013  0.743
2011 Majerus PW. Wandering through the laboratory. The Journal of Biological Chemistry. 286: 4941-5. PMID 21169350 DOI: 10.1074/Jbc.X110.212894  0.343
2011 Marjanovic J, Wilson MP, Zhang C, Zou J, Nicholas P, Majerus PW. The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model. Advances in Enzyme Regulation. 51: 101-5. PMID 21110994 DOI: 10.1016/J.Advenzreg.2010.11.006  0.341
2010 Majerus PW, Wilson DB, Zhang C, Nicholas PJ, Wilson MP. Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects. Advances in Enzyme Regulation. 50: 365-72. PMID 19914276 DOI: 10.1016/J.Advenzreg.2009.10.017  0.322
2009 Bielas SL, Silhavy JL, Brancati F, Kisseleva MV, Al-Gazali L, Sztriha L, Bayoumi RA, Zaki MS, Abdel-Aleem A, Rosti RO, Kayserili H, Swistun D, Scott LC, Bertini E, Boltshauser E, ... ... Majerus PW, et al. Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies. Nature Genetics. 41: 1032-6. PMID 19668216 DOI: 10.1038/Ng.423  0.764
2009 Wilson MP, Hugge C, Bielinska M, Nicholas P, Majerus PW, Wilson DB. Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase. Proceedings of the National Academy of Sciences of the United States of America. 106: 9831-5. PMID 19482943 DOI: 10.1073/Pnas.0904172106  0.316
2009 Ivetac I, Gurung R, Hakim S, Horan KA, Sheffield DA, Binge LC, Majerus PW, Tiganis T, Mitchell CA. Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. Embo Reports. 10: 487-93. PMID 19325558 DOI: 10.1038/Embor.2009.28  0.372
2009 Zou J, Chang SC, Marjanovic J, Majerus PW. MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis. The Journal of Biological Chemistry. 284: 2064-71. PMID 19038970 DOI: 10.1074/Jbc.M804292200  0.38
2009 Majerus PW, York JD. Phosphoinositide phosphatases and disease. Journal of Lipid Research. 50: S249-54. PMID 19001665 DOI: 10.1194/Jlr.R800072-Jlr200  0.613
2008 Majerus PW, Zou J, Marjanovic J, Kisseleva MV, Wilson MP. The role of inositol signaling in the control of apoptosis. Advances in Enzyme Regulation. 48: 10-7. PMID 18486622 DOI: 10.1016/J.Advenzreg.2008.04.001  0.773
2007 Majerus PW. A discrete signaling function for an inositol pyrophosphate. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe72. PMID 18073384 DOI: 10.1126/Stke.4162007Pe72  0.352
2007 Zou J, Marjanovic J, Kisseleva MV, Wilson M, Majerus PW. Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 16834-9. PMID 17940011 DOI: 10.1073/Pnas.0708189104  0.773
2006 Chang SC, Majerus PW. Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate. Biochemical and Biophysical Research Communications. 339: 209-16. PMID 16293229 DOI: 10.1016/J.Bbrc.2005.10.201  0.408
2005 Ungewickell A, Hugge C, Kisseleva M, Chang SC, Zou J, Feng Y, Galyov EE, Wilson M, Majerus PW. The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Proceedings of the National Academy of Sciences of the United States of America. 102: 18854-9. PMID 16365287 DOI: 10.1073/Pnas.0509740102  0.773
2005 Verbsky J, Majerus PW. Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis. The Journal of Biological Chemistry. 280: 29263-8. PMID 15967797 DOI: 10.1074/Jbc.M503366200  0.657
2005 Verbsky J, Lavine K, Majerus PW. Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 8448-53. PMID 15939868 DOI: 10.1073/Pnas.0503656102  0.67
2005 Miller GJ, Wilson MP, Majerus PW, Hurley JH. Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Molecular Cell. 18: 201-12. PMID 15837423 DOI: 10.1016/J.Molcel.2005.03.016  0.375
2005 Ivetac I, Munday AD, Kisseleva MV, Zhang XM, Luff S, Tiganis T, Whisstock JC, Rowe T, Majerus PW, Mitchell CA. The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane. Molecular Biology of the Cell. 16: 2218-33. PMID 15716355 DOI: 10.1091/Mbc.E04-09-0799  0.772
2005 Verbsky JW, Chang SC, Wilson MP, Mochizuki Y, Majerus PW. The pathway for the production of inositol hexakisphosphate in human cells. The Journal of Biological Chemistry. 280: 1911-20. PMID 15531582 DOI: 10.1074/Jbc.M411528200  0.697
2004 Ungewickell A, Ward ME, Ungewickell E, Majerus PW. The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin. Proceedings of the National Academy of Sciences of the United States of America. 101: 13501-6. PMID 15353600 DOI: 10.1073/Pnas.0405664101  0.756
2004 Rayala HJ, Kendirgi F, Barry DM, Majerus PW, Wente SR. The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Molecular & Cellular Proteomics : McP. 3: 145-55. PMID 14645504 DOI: 10.1074/Mcp.M300106-Mcp200  0.325
2003 Sun Y, Mochizuki Y, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis. The Journal of Biological Chemistry. 278: 43645-53. PMID 12925536 DOI: 10.1074/Jbc.M300674200  0.312
2003 Mochizuki Y, Majerus PW. Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9. Proceedings of the National Academy of Sciences of the United States of America. 100: 9768-73. PMID 12890864 DOI: 10.1073/Pnas.1333958100  0.405
2003 Nandurkar HH, Layton M, Laporte J, Selan C, Corcoran L, Caldwell KK, Mochizuki Y, Majerus PW, Mitchell CA. Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP. Proceedings of the National Academy of Sciences of the United States of America. 100: 8660-5. PMID 12847286 DOI: 10.1073/Pnas.1033097100  0.399
2002 Sun Y, Wilson MP, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1. The Journal of Biological Chemistry. 277: 45759-64. PMID 12324474 DOI: 10.1074/Jbc.M208709200  0.343
2002 Chang SC, Miller AL, Feng Y, Wente SR, Majerus PW. The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase. The Journal of Biological Chemistry. 277: 43836-43. PMID 12223481 DOI: 10.1074/Jbc.M206134200  0.412
2002 Verbsky JW, Wilson MP, Kisseleva MV, Majerus PW, Wente SR. The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. The Journal of Biological Chemistry. 277: 31857-62. PMID 12084730 DOI: 10.1074/Jbc.M205682200  0.788
2002 Kisseleva MV, Cao L, Majerus PW. Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death. The Journal of Biological Chemistry. 277: 6266-72. PMID 11706019 DOI: 10.1074/Jbc.M105969200  0.788
2001 Wilson MP, Sun Y, Cao L, Majerus PW. Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2. The Journal of Biological Chemistry. 276: 40998-1004. PMID 11533064 DOI: 10.1074/Jbc.M106605200  0.34
2001 Nandurkar HH, Caldwell KK, Whisstock JC, Layton MJ, Gaudet EA, Norris FA, Majerus PW, Mitchell CA. Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity. Proceedings of the National Academy of Sciences of the United States of America. 98: 9499-504. PMID 11504939 DOI: 10.1073/Pnas.171306098  0.4
2001 Feng Y, Wente SR, Majerus PW. Overexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA export. Proceedings of the National Academy of Sciences of the United States of America. 98: 875-9. PMID 11158563 DOI: 10.1073/Pnas.98.3.875  0.338
2000 Vyas P, Norris FA, Joseph R, Majerus PW, Orkin SH. Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 97: 13696-701. PMID 11087841 DOI: 10.1073/Pnas.250476397  0.3
2000 Field J, Wilson MP, Mai Z, Majerus PW, Samuelson J. An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity. Molecular and Biochemical Parasitology. 108: 119-123. PMID 10802324 DOI: 10.1016/S0166-6851(00)00197-3  0.315
2000 Kisseleva MV, Wilson MP, Majerus PW. The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase. The Journal of Biological Chemistry. 275: 20110-6. PMID 10764818 DOI: 10.1074/Jbc.M910119199  0.783
2000 Kunz J, Wilson MP, Kisseleva M, Hurley JH, Majerus PW, Anderson RA. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Molecular Cell. 5: 1-11. PMID 10678164 DOI: 10.1016/S1097-2765(00)80398-6  0.781
1999 Ungewickell AJ, Majerus PW. Increased levels of plasma lysosomal enzymes in patients with Lowe syndrome. Proceedings of the National Academy of Sciences of the United States of America. 96: 13342-4. PMID 10557322 DOI: 10.1073/Pnas.96.23.13342  0.759
1999 Majerus PW, Kisseleva MV, Norris FA. The role of phosphatases in inositol signaling reactions. The Journal of Biological Chemistry. 274: 10669-72. PMID 10196133 DOI: 10.1074/Jbc.274.16.10669  0.744
1999 Munday AD, Norris FA, Caldwell KK, Brown S, Majerus PW, Mitchell CA. The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol. Proceedings of the National Academy of Sciences of the United States of America. 96: 3640-5. PMID 10097090 DOI: 10.1073/Pnas.96.7.3640  0.407
1998 Norris FA, Wilson MP, Wallis TS, Galyov EE, Majerus PW. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 95: 14057-9. PMID 9826652 DOI: 10.1073/Pnas.95.24.14057  0.345
1998 Roach TI, Slater SE, White LS, Zhang X, Majerus PW, Brown EJ, Thomas ML. The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages. Current Biology : Cb. 8: 1035-8. PMID 9740804 DOI: 10.1016/S0960-9822(07)00426-5  0.327
1998 Zhang X, Majerus PW. Phosphatidylinositol signalling reactions Seminars in Cell and Developmental Biology. 9: 153-160. PMID 9599410 DOI: 10.1006/Scdb.1997.0220  0.371
1998 Zhang X, Hartz PA, Philip E, Racusen LC, Majerus PW. Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 273: 1574-82. PMID 9430698 DOI: 10.1074/Jbc.273.3.1574  0.375
1997 Norris FA, Atkins RC, Majerus PW. The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family. The Journal of Biological Chemistry. 272: 23859-64. PMID 9295334 DOI: 10.1074/Jbc.272.38.23859  0.391
1997 Zhang X, Loijens JC, Boronenkov IV, Parker GJ, Norris FA, Chen J, Thum O, Prestwich GD, Majerus PW, Anderson RA. Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. The Journal of Biological Chemistry. 272: 17756-61. PMID 9211928 DOI: 10.1074/Jbc.272.28.17756  0.368
1997 Wilson MP, Majerus PW. Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase Biochemical and Biophysical Research Communications. 232: 678-681. PMID 9126335 DOI: 10.1006/Bbrc.1997.6355  0.385
1997 Jefferson AB, Auethavekiat V, Pot DA, Williams LT, Majerus PW. Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association. The Journal of Biological Chemistry. 272: 5983-8. PMID 9038219 DOI: 10.1074/Jbc.272.9.5983  0.427
1997 Auethavekiat V, Abrams CS, Majerus PW. Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I Journal of Biological Chemistry. 272: 1786-1790. PMID 8999861 DOI: 10.1074/Jbc.272.3.1786  0.413
1996 Liu L, Jefferson AB, Zhang X, Norris FA, Majerus PW, Krystal G. A novel phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase associates with the interleukin-3 receptor. The Journal of Biological Chemistry. 271: 29729-33. PMID 8939907 DOI: 10.1074/Jbc.271.47.29729  0.322
1996 Gu M, Meng K, Majerus PW. The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells Proceedings of the National Academy of Sciences of the United States of America. 93: 12980-12985. PMID 8917530 DOI: 10.1073/Pnas.93.23.12980  0.34
1996 Osborne MA, Zenner G, Lubinus M, Zhang X, Songyang Z, Cantley LC, Majerus P, Burn P, Kochan JP. The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation Journal of Biological Chemistry. 271: 29271-29278. PMID 8910587 DOI: 10.1074/Jbc.271.46.29271  0.383
1996 Gu M, Majerus PW. The properties of the protein tyrosine phosphatase PTPMEG Journal of Biological Chemistry. 271: 27751-27759. PMID 8910369 DOI: 10.1074/Jbc.271.44.27751  0.434
1996 Kavanaugh WM, Pot DA, Chin SM, Deuter-Reinhard M, Jefferson AB, Norris FA, Masiarz FR, Cousens LS, Majerus PW, Williams LT. Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2. Current Biology : Cb. 6: 438-45. PMID 8723348 DOI: 10.1016/S0960-9822(02)00511-0  0.37
1996 Jefferson AB, Majerus PW. Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases. Biochemistry. 35: 7890-4. PMID 8672490 DOI: 10.1021/Bi9602627  0.4
1996 Wilson MP, Majerus PW. Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning, and expression of the recombinant enzyme Journal of Biological Chemistry. 271: 11904-11910. PMID 8662638 DOI: 10.1074/Jbc.271.20.11904  0.372
1996 Damen JE, Liu L, Rosten P, Humphries RK, Jefferson AB, Majerus PW, Krystal G. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 93: 1689-93. PMID 8643691 DOI: 10.1073/Pnas.93.4.1689  0.393
1995 York JD, Ponder JW, Majerus PW. Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proceedings of the National Academy of Sciences of the United States of America. 92: 5149-53. PMID 7761465 DOI: 10.1073/Pnas.92.11.5149  0.636
1995 Zhang X, Jefferson AB, Auethavekiat V, Majerus PW. The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 92: 4853-6. PMID 7761412 DOI: 10.1073/Pnas.92.11.4853  0.42
1995 Jefferson AB, Majerus PW. Properties of type II inositol polyphosphate 5-phosphatase. The Journal of Biological Chemistry. 270: 9370-7. PMID 7721860 DOI: 10.1074/Jbc.270.16.9370  0.37
1995 Norris FA, Auethavekiat V, Majerus PW. The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase. The Journal of Biological Chemistry. 270: 16128-33. PMID 7608176 DOI: 10.1074/Jbc.270.27.16128  0.344
1994 York JD, Chen ZW, Ponder JW, Chauhan AK, Mathews FS, Majerus PW. Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells. Journal of Molecular Biology. 236: 584-9. PMID 8107142 DOI: 10.1006/Jmbi.1994.1167  0.648
1994 York JD, Ponder JW, Chen ZW, Mathews FS, Majerus PW. Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution. Biochemistry. 33: 13164-71. PMID 7947723 DOI: 10.1021/Bi00249A002  0.606
1993 Miletich JP, Prescott SM, White R, Majerus PW, Bovill EG. Inherited predisposition to thrombosis Cell. 72: 477-480. PMID 8440014 DOI: 10.1016/0092-8674(93)90063-V  0.541
1993 York JD, Veile RA, Donis-Keller H, Majerus PW. Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 90: 5833-7. PMID 8390685 DOI: 10.1073/Pnas.90.12.5833  0.635
1992 Gu M, Warshawsky I, Majerus PW. Cloning and expression of a cytosolic megakaryocyte protein-tyrosine- phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p Proceedings of the National Academy of Sciences of the United States of America. 89: 2980-2984. PMID 1557404 DOI: 10.1073/Pnas.89.7.2980  0.4
1992 Majerus PW. Inositol phosphate biochemistry Annual Review of Biochemistry. 61: 225-250. PMID 1323235 DOI: 10.1146/Annurev.Bi.61.070192.001301  0.361
1991 Cunningham TW, Majerus PW. Pathway for the formation of D-3 phosphate containing inositol phospholipids in PDGF stimulated NIH 3T3 fibroblasts. Biochemical and Biophysical Research Communications. 175: 568-76. PMID 1850246 DOI: 10.1016/0006-291X(91)91603-A  0.35
1991 Neuwald AF, York JD, Majerus PW. Diverse proteins homologous to inositol monophosphatase. Febs Letters. 294: 16-8. PMID 1660408 DOI: 10.1016/0014-5793(91)81332-3  0.649
1991 Walsh JP, Caldwell KK, Majerus PW. Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 88: 9184-7. PMID 1656463 DOI: 10.1073/Pnas.88.20.9184  0.315
1991 Gu MX, York JD, Warshawsky I, Majerus PW. Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. Proceedings of the National Academy of Sciences of the United States of America. 88: 5867-71. PMID 1648233 DOI: 10.1073/Pnas.88.13.5867  0.662
1990 Majerus PW, Ross TS, Cunningham TW, Caldwell KK, Jefferson AB, Bansal VS. Recent insights in phosphatidylinositol signaling. Cell. 63: 459-65. PMID 2225061 DOI: 10.1016/0092-8674(90)90442-H  0.352
1990 York JD, Majerus PW. Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 87: 9548-52. PMID 2175905 DOI: 10.1073/Pnas.87.24.9548  0.657
1990 Mitchell CA, Jefferson AB, Bejeck BE, Brugge JS, Deuel TF, Majerus PW. Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets. Proceedings of the National Academy of Sciences of the United States of America. 87: 9396-400. PMID 2174561 DOI: 10.1073/Pnas.87.23.9396  0.376
1990 Ross TS, Tait JF, Majerus PW. Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III Science. 248: 605-607. PMID 2159184 DOI: 10.1126/Science.2159184  0.373
1988 Lips DL, Bross TE, Majerus PW. Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate [a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate] from Swiss mouse 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 85: 88-92. PMID 3422429 DOI: 10.1073/Pnas.85.1.88  0.331
1987 Auchus RJ, Kaiser SL, Majerus PW. Synthesis of inositol 1,2-(cyclic)-4,5-trisphosphate Proceedings of the National Academy of Sciences of the United States of America. 84: 1206-1209. PMID 3469663 DOI: 10.1073/Pnas.84.5.1206  0.312
1987 Laposata M, Kaiser SL, Reich EL, Majerus PW. Eicosadiynoic acid: A non-toxic inhibitor of multiple enzymatic steps in the production of icosanoids from arachidonic acid Prostaglandins. 33: 603-614. PMID 3110863 DOI: 10.1016/0090-6980(87)90284-X  0.313
1987 Laposata M, Majerus PW. Measurement of icosanoid precursor uptake and release by intact cells Methods in Enzymology. 350-355. PMID 3110552 DOI: 10.1016/0076-6879(87)41082-3  0.31
1987 Maruyama I, Majerus PW. Protein C inhibits endocytosis of thrombin-thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells Blood. 69: 1481-1484. PMID 3032308 DOI: 10.1182/Blood.V69.5.1481.Bloodjournal6951481  0.331
1987 Inhorn RC, Bansal VS, Majerus PW. Pathway for inositol 1,3,4-triphosphate and 1,4-biphosphate metabolism Proceedings of the National Academy of Sciences of the United States of America. 84: 2170-2174. PMID 3031669 DOI: 10.1073/Pnas.84.8.2170  0.357
1987 Wen DZ, Dittman WA, Ye RD, Deaven LL, Majerus PW, Sadler JE. Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene. Biochemistry. 26: 4350-7. PMID 2822087 DOI: 10.1021/Bi00388A025  0.316
1986 Connolly TM, Lawing WJ, Majerus PW. Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity Cell. 46: 951-958. PMID 3019558 DOI: 10.1016/0092-8674(86)90077-2  0.39
1986 Ishii H, Connolly TM, Bross TE, Majerus PW. Inositol cyclic trisphosphate [inositol 1,2-(cyclic)-4,5-trisphosphate] is formed upon thrombin stimulation of human platelets Proceedings of the National Academy of Sciences of the United States of America. 83: 6397-6401. PMID 3018731 DOI: 10.1073/Pnas.83.17.6397  0.326
1985 Auchus RJ, Wilson DB, Covey DF, Majerus PW. The 5-hydroxyl of myo-inositol is essential for uptake into HSDM1C1 mouse fibrosarcoma cells Biochemical and Biophysical Research Communications. 130: 1139-1146. PMID 4026861 DOI: 10.1016/0006-291X(85)91734-6  0.344
1985 Ishii H, Majerus PW. Thrombomodulin is present in human plasma and urine Journal of Clinical Investigation. 76: 2178-2181. PMID 3001144 DOI: 10.1172/Jci112225  0.325
1985 Wilson DB, Bross TE, Sherman WR, Berger RA, Majerus PW. Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes. Proceedings of the National Academy of Sciences of the United States of America. 82: 4013-7. PMID 2987959 DOI: 10.1073/Pnas.82.12.4013  0.33
1985 Maruyama I, Salem HH, Ishii H, Majerus PW. Human thrombomodulin is not an efficient inhibitor of the procoagulant activity of thrombin Journal of Clinical Investigation. 75: 987-991. PMID 2984256 DOI: 10.1172/Jci111800  0.343
1984 Maruyama I, Salem HH, Majerus PW. Coagulation Factor V(a) binds to human umbilical vein endothelial cells and accelerates protein C activation Journal of Clinical Investigation. 74: 224-230. PMID 6547457 DOI: 10.1172/Jci111405  0.32
1984 Majerus PW, Neufeld EJ, Wilson DB. Production of phosphoinositide-derived messengers Cell. 37: 701-703. PMID 6331677 DOI: 10.1016/0092-8674(84)90405-7  0.39
1984 Salem HH, Esmon NL, Esmon CT, Majerus PW. Effects of thrombomodulin and coagulation Factor Va-light chain on protein C activation in vitro. Journal of Clinical Investigation. 73: 968-972. PMID 6323539 DOI: 10.1172/Jci111321  0.316
1983 Prescott SM, Majerus PW. Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate Journal of Biological Chemistry. 258: 764-769. PMID 6822511  0.583
1983 Salem HH, Broze GJ, Miletich JP, Majerus PW. Human coagulation factor V(a) is a cofactor for the activation of protein C Proceedings of the National Academy of Sciences of the United States of America. 80: 1584-1588. PMID 6572921 DOI: 10.1073/Pnas.80.6.1584  0.303
1983 Bross TE, Prescott SM, Majerus PW. RHC 80267 does not inhibit the diglyceride lipase pathway in intact platelets Biochemical and Biophysical Research Communications. 116: 68-74. PMID 6416255 DOI: 10.1016/0006-291X(83)90381-9  0.594
1983 Neufeld EJ, Wilson DB, Sprecher H, Majerus PW. High affinity esterification of eicosanoid precursor fatty acids by platelets Journal of Clinical Investigation. 72: 214-220. PMID 6308046 DOI: 10.1172/Jci110959  0.305
1983 Majerus PW, Prescott SM, Hofmann SL, Neufeld EJ, Wilson DB. Uptake and release of arachidonate by platelets. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 11: 45-52. PMID 6221562  0.513
1982 Majerus PW, Prescott SM. Characterization and assay of diacylglycerol lipase from human platelets. Methods in Enzymology. 86: 11-7. PMID 7132746 DOI: 10.1016/0076-6879(82)86162-4  0.613
1982 Wilson DB, Prescott SM, Majerus PW. Discovery of an arachidonoyl coenzyme A synthetase in human platelets Journal of Biological Chemistry. 257: 3510-3515. PMID 7061494  0.575
1982 McEver RP, Baenziger JU, Majerus PW. Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets Blood. 59: 80-85. PMID 7053767 DOI: 10.1182/Blood.V59.1.80.80  0.564
1982 Laposata M, Prescott SM, Bross TE, Majerus PW. Development and characterization of a tissue culture cell line with essential fatty acid deficiency Proceedings of the National Academy of Sciences of the United States of America. 79: 7654-7658. PMID 6961441 DOI: 10.1073/Pnas.79.24.7654  0.601
1982 Hofmann SL, Prescott SM, Majerus PW. The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets Archives of Biochemistry and Biophysics. 215: 237-244. PMID 6807207 DOI: 10.1016/0003-9861(82)90300-9  0.617
1981 Prescott SM, Majerus PW. The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets Journal of Biological Chemistry. 256: 579-582. PMID 7451460  0.566
1981 Broze GJ, Majerus PW. [19] Human factor VII Methods in Enzymology. 80: 228-237. DOI: 10.1016/S0076-6879(81)80021-3  0.316
1980 Bell RL, Baenziger NL, Majerus PW. Bradykinin-stimulated release of arachidonate from phosphatidyl inositol in mouse fibrosarcoma cells. Prostaglandins. 20: 269-74. PMID 7413991 DOI: 10.1016/S0090-6980(80)80045-1  0.343
1980 McEver RP, Baenziger NL, Majerus PW. Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody. The Journal of Clinical Investigation. 66: 1311-8. PMID 6449521 DOI: 10.1172/Jci109983  0.559
1979 Bell RL, Kennerly DA, Stanford N, Majerus PW. Diglyceride lipase: a pathway for arachidonate release from human platelets. Proceedings of the National Academy of Sciences of the United States of America. 76: 3238-41. PMID 290999 DOI: 10.1073/Pnas.76.7.3238  0.343
1979 Baenziger NL, Becherer PR, Majerus PW. Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts. Cell. 16: 967-74. PMID 110457 DOI: 10.1016/0092-8674(79)90111-9  0.309
1978 Burch JW, Baenziger NL, Stanford N, Majerus PW. Sensitivity of fatty acid cyclooxygenase from human aorta to acetylation by aspirin. Proceedings of the National Academy of Sciences of the United States of America. 75: 5181-4. PMID 105363 DOI: 10.1073/Pnas.75.10.5181  0.305
1977 Roth GJ, Stanford N, Jacobs JW, Majerus PW. Acetylation of prostaglandin synthetase by aspirin. Purification and properties of the acetylated protein from sheep vesicular gland Biochemistry. 16: 4244-4248. PMID 409429 DOI: 10.1021/Bi00638A018  0.353
1977 Majerus PW, Stanford N. Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles British Journal of Clinical Pharmacology. 4. PMID 406909 DOI: 10.1111/J.1365-2125.1977.Tb04509.X  0.336
1977 Stanford N, Roth GJ, Shen TY, Majerus PW. Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin Prostaglandins. 13: 669-675. PMID 404672 DOI: 10.1016/0090-6980(77)90237-4  0.319
1977 Minkes M, Stanford N, Chi MM, Roth GJ, Raz A, Needleman P, Majerus PW. Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions. The Journal of Clinical Investigation. 59: 449-54. PMID 190267 DOI: 10.1172/Jci108659  0.322
1976 Rome LH, Lands WE, Roth GJ, Majerus PW. Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins. Prostaglandins. 11: 23-30. PMID 176688 DOI: 10.1016/0090-6980(76)90169-6  0.336
1975 Shuman MA, Majerus PW. The perturbation of thrombin binding to human platelets by anions Journal of Clinical Investigation. 56: 945-950. PMID 1159095 DOI: 10.1172/Jci108174  0.3
1975 Roth GJ, Majerus PW. The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein Journal of Clinical Investigation. 56: 624-632. PMID 1159076 DOI: 10.1172/Jci108132  0.354
1975 Roth GJ, Stanford N, Majerus PW. Acetylation of prostaglandin synthase by aspirin Proceedings of the National Academy of Sciences of the United States of America. 72: 3073-3076. PMID 810797 DOI: 10.1073/Pnas.72.8.3073  0.364
1975 Lyons RM, Stanford N, Majerus PW. Thrombin induced protein phosphorylation in human platelets Journal of Clinical Investigation. 56: 924-936. PMID 169298 DOI: 10.1172/Jci108172  0.402
1972 Brodie GN, Baenziger NL, Chase LR, Majerus PW. The effects of thrombin on adenyl cyclase activity and a membrane protein from human platelets. The Journal of Clinical Investigation. 51: 81-8. PMID 4331802 DOI: 10.1172/Jci106800  0.351
1971 Minnich V, Smith MB, Brauner MJ, Majerus PW. Glutathione biosynthesis in human erythrocytes. I. Identification of the enzymes of glutathione synthesis in hemolysates Journal of Clinical Investigation. 50: 507-513. PMID 5545117 DOI: 10.1172/Jci106519  0.334
1971 Baenziger NL, Brodie GN, Majerus PW. A thrombin-sensitive protein of human platelet membranes. Proceedings of the National Academy of Sciences of the United States of America. 68: 240-3. PMID 5276296 DOI: 10.1073/Pnas.68.1.240  0.328
1971 Majerus PW, Brauner MJ, Smith MB, Minnich V. Glutathione synthesis in human erythrocytes. II. Purification and properties of the enzymes of glutathione biosynthesis Journal of Clinical Investigation. 50: 1637-1643. PMID 5097571 DOI: 10.1172/Jci106652  0.363
1969 Majerus PW, Smith MB, Clamon GH. Lipid metabolism in human platelets. I. Evidence for a complete fatty acid synthesizing system Journal of Clinical Investigation. 48: 156-164. PMID 5765018 DOI: 10.1172/Jci105964  0.369
1969 Lewis N, Majerus PW. Lipid metabolism in human platelets. II. De novo phospholipid synthesis and the effect of thrombin on the pattern of synthesis Journal of Clinical Investigation. 48: 2114-2123. PMID 4309956 DOI: 10.1172/Jci106178  0.355
1969 Alberts AW, Majerus PW, Roy Vagelos P. [8] Malonyl-CoA acyl carrier protein transacylase Methods in Enzymology. 14: 53-56. DOI: 10.1016/S0076-6879(69)14010-0  0.322
1969 Alberts AW, Majerus PW, Roy Vagelos P. [7] Acetyl-CoA acyl carrier protein transacylase Methods in Enzymology. 14: 50-53. DOI: 10.1016/S0076-6879(69)14009-4  0.32
1969 Majerus PW, Alberts AW, Roy Vagelos P. [6] Acyl carrier protein from Escherichia coli Methods in Enzymology. 14: 43-50. DOI: 10.1016/S0076-6879(69)14008-2  0.306
1968 Majerus PW. Acyl carrier protein: Effects of acetylation and tryptic hydrolysis on function in fatty acid synthesis Science. 159: 428-430. DOI: 10.1126/Science.159.3813.428  0.337
1967 Majerus PW, Lastra R. Fatty acid biosynthesis in human leukocytes Journal of Clinical Investigation. 46: 1596-1602. PMID 6061737 DOI: 10.1172/Jci105651  0.315
1967 Majerus PW, Vagelos PR. Fatty acid biosynthesis and the role of the acyl carrier protein. Advances in Lipid Research. 5: 1-33. PMID 4866072  0.549
1966 Rudney H, Stewart PR, Majerus PW, Vagelos PR. The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. V. The role of acyl carrier protein. The Journal of Biological Chemistry. 241: 1226-8. PMID 5933879  0.5
1966 Vagelos PR, Majerus PW, Alberts AW, Larrabee AR, Ailhaud GP. Structure and function of the acyl carrier protein. Federation Proceedings. 25: 1485-94. PMID 5332188  0.525
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN. Proceedings of the National Academy of Sciences of the United States of America. 53: 410-7. PMID 14294075  0.534
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS. The Journal of Biological Chemistry. 240: 618-21. PMID 14275113  0.544
1965 Majerus PW, Alberts AW, Vagelos PR. Acyl carrier protein. VII. The primary structure of the substrate-binding site. The Journal of Biological Chemistry. 240: 4723-6. PMID 5321310  0.53
1965 Vagelos PR, Alberts AW, Majerus PW. The mechanism of fatty acid biosynthesis and the involvement of an acyl carrier protein. Annals of the New York Academy of Sciences. 131: 177-88. PMID 5216961 DOI: 10.1111/J.1749-6632.1965.Tb34787.X  0.59
1965 Alberts AW, Majerus PW, Vagelos PR. Acyl carrier protein. VI. Purification and properties of β-ketoacyl acyl carrier protein synthetase Biochemistry. 4: 2265-2274. DOI: 10.1021/Bi00887A002  0.576
1964 ALBERTS AW, MAJERUS PW, TALAMO B, VAGELOS PR. ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS. Biochemistry. 3: 1563-71. PMID 14232033 DOI: 10.1021/Bi00898A030  0.584
1964 MAJERUS PW, ALBERTS AW, VAGELOS PR. THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE. Proceedings of the National Academy of Sciences of the United States of America. 51: 1231-8. PMID 14215649  0.544
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