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R Michael Garavito - Publications

Affiliations: 
1987-1995 Biochemistry and Molecular Biology University of Chicago, Chicago, IL 
 1995- Biochemistry and Molecular Biology Michigan State University, East Lansing, MI 
Area:
biochemistry, structural biology, enzymology, biological mechanisms, membrane proteins
Website:
https://bmb.natsci.msu.edu/faculty/r-michael-garavito/
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu J, Hiser C, Li F, Hall R, Garavito RM, Ferguson-Miller S. Correction to "New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity". Biochemistry. PMID 37192273 DOI: 10.1021/acs.biochem.3c00208  0.317
2023 Liu J, Hiser C, Li F, Hall R, Garavito RM, Ferguson-Miller S. New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry. PMID 36947867 DOI: 10.1021/acs.biochem.2c00612  0.378
2015 Li F, Liu J, Zheng Y, Garavito RM, Ferguson-Miller S. Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism. Science (New York, N.Y.). 347: 555-8. PMID 25635101 DOI: 10.1126/Science.1260590  0.307
2014 Xu S, Hermanson DJ, Banerjee S, Ghebreselasie K, Clayton GM, Garavito RM, Marnett LJ. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. The Journal of Biological Chemistry. 289: 6799-808. PMID 24425867 DOI: 10.1074/Jbc.M113.517987  0.33
2009 King JD, Poon KK, Webb NA, Anderson EM, McNally DJ, Brisson JR, Messner P, Garavito RM, Lam JS. The structural basis for catalytic function of GMD and RMD, two closely related enzymes from the GDP-D-rhamnose biosynthesis pathway. The Febs Journal. 276: 2686-700. PMID 19459932 DOI: 10.1111/J.1742-4658.2009.06993.X  0.61
2007 Harman CA, Turman MV, Kozak KR, Marnett LJ, Smith WL, Garavito RM. Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indomethacin ethanolamides. The Journal of Biological Chemistry. 282: 28096-105. PMID 17656360 DOI: 10.1074/Jbc.M701335200  0.732
2006 Qin L, Hiser C, Mulichak A, Garavito RM, Ferguson-Miller S. Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 103: 16117-22. PMID 17050688 DOI: 10.1073/Pnas.0606149103  0.373
2006 Powers RA, Rife CL, Schilmiller AL, Howe GA, Garavito RM. Structure determination and analysis of acyl-CoA oxidase (ACX1) from tomato. Acta Crystallographica. Section D, Biological Crystallography. 62: 683-6. PMID 16699197 DOI: 10.1107/S0907444906014107  0.308
2004 Harman CA, Rieke CJ, Garavito RM, Smith WL. Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid. The Journal of Biological Chemistry. 279: 42929-35. PMID 15292194 DOI: 10.1074/Jbc.M403013200  0.742
2004 Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM. Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands. Biochemistry. 43: 5170-80. PMID 15122882 DOI: 10.1021/Bi036130C  0.355
2004 Webb NA, Mulichak AM, Lam JS, Rocchetta HL, Garavito RM. Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway. Protein Science : a Publication of the Protein Society. 13: 529-39. PMID 14739333 DOI: 10.1110/Ps.03393904  0.638
2003 Mulichak AM, Losey HC, Lu W, Wawrzak Z, Walsh CT, Garavito RM. Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 9238-43. PMID 12874381 DOI: 10.1073/Pnas.1233577100  0.365
2002 Mulichak AM, Bonin CP, Reiter WD, Garavito RM. Structure of the MUR1 GDP-mannose 4,6-dehydratase from Arabidopsis thaliana: implications for ligand binding and specificity. Biochemistry. 41: 15578-89. PMID 12501186 DOI: 10.1021/bi0266683  0.34
2002 Garavito RM, Malkowski MG, DeWitt DL. The structures of prostaglandin endoperoxide H synthases-1 and -2. Prostaglandins & Other Lipid Mediators. 68: 129-52. PMID 12432914 DOI: 10.1016/S0090-6980(02)00026-6  0.335
2001 Thuresson ED, Malkowski MG, Lakkides KM, Rieke CJ, Mulichak AM, Ginell SL, Garavito RM, Smith WL. Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases. The Journal of Biological Chemistry. 276: 10358-65. PMID 11121413 DOI: 10.1074/Jbc.M009378200  0.318
2001 Thuresson ED, Lakkides KM, Rieke CJ, Sun Y, Wingerd BA, Micielli R, Mulichak AM, Malkowski MG, Garavito RM, Smith WL. Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid. The Journal of Biological Chemistry. 276: 10347-57. PMID 11121412 DOI: 10.1074/Jbc.M009377200  0.357
2000 Malkowski MG, Theisen MJ, Scharmen A, Garavito RM. The formation of stable fatty acid substrate complexes in prostaglandin H(2) synthase-1. Archives of Biochemistry and Biophysics. 380: 39-45. PMID 10900130 DOI: 10.1006/Abbi.2000.1906  0.326
1999 Mulichak AM, Theisen MJ, Essigmann B, Benning C, Garavito RM. Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose. Proceedings of the National Academy of Sciences of the United States of America. 96: 13097-102. PMID 10557279 DOI: 10.1073/Pnas.96.23.13097  0.318
1997 Picot D, Loll PJ, Garavito RM. X-ray crystallographic study of the structure of prostaglandin H synthase. Advances in Experimental Medicine and Biology. 400: 107-11. PMID 9547544  0.585
1996 Loll PJ, Garavito RM, Carrell CJ, Carrell HL. 1-(4-iodobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, an iodinated indomethacin analog. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 455-7. PMID 8829363  0.604
1996 Loll PJ, Garavito RM, Carrell CJ, Carrell HL. 2-bromoacetoxybenzoic acid, a brominated aspirin analog. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 375-7. PMID 8829360  0.625
1996 Garavito RM, Picot D, Loll PJ. Strategies for crystallizing membrane proteins. Journal of Bioenergetics and Biomembranes. 28: 13-27. PMID 8786233  0.596
1996 Loll PJ, Picot D, Ekabo O, Garavito RM. Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Biochemistry. 35: 7330-40. PMID 8652509 DOI: 10.1021/bi952776w  0.684
1996 Bhattacharyya DK, Lecomte M, Rieke CJ, Garavito RM, Smith WL. Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1 Journal of Biological Chemistry. 271: 2179-2184. PMID 8567676 DOI: 10.1074/JBC.271.4.2179  0.33
1996 Loll PJ, Garavito RM, Carrell CJ, Carrell HL. 2-bromoacetoxybenzoic acid, a brominated aspirin analog Acta Crystallographica Section C: Crystal Structure Communications. 52: 375-377.  0.617
1995 Garavito RM, Picot D, Loll PJ. Preliminary X-Ray Investigations Into NSAID-Binding to Cyclooxygenase-1. American Journal of Therapeutics. 2: 611-615. PMID 11854835  0.634
1995 Pebay-Peyroula E, Garavito RM, Rosenbusch JP, Zulauf M, Timmins PA. Detergent structure in tetragonal crystals of OmpF porin. Structure (London, England : 1993). 3: 1051-9. PMID 8590000 DOI: 10.1016/S0969-2126(01)00241-6  0.323
1995 Harlan JE, Picot D, Loll PJ, Garavito RM. Calibration of size-exclusion chromatography: use of a double Gaussian distribution function to describe pore sizes. Analytical Biochemistry. 224: 557-63. PMID 7733458 DOI: 10.1006/abio.1995.1087  0.529
1995 Garavito RM, Picot D, Loll PJ. The 3.1 A X-ray crystal structure of the integral membrane enzyme prostaglandin H2 synthase-1. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 99-103. PMID 7732912  0.639
1995 Loll PJ, Quirk S, Lattman EE, Garavito RM. X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide. Biochemistry. 34: 4316-24. PMID 7703245  0.717
1995 Loll PJ, Picot D, Garavito RM. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nature Structural Biology. 2: 637-43. PMID 7552725 DOI: 10.1038/nsb0895-637  0.66
1994 Picot D, Loll PJ, Garavito RM. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature. 367: 243-9. PMID 8121489 DOI: 10.1038/367243a0  0.658
1994 Garavito RM, Picot D, Loll PJ. Prostaglandin H synthase Current Opinion in Structural Biology. 4: 529-535. DOI: 10.1016/S0959-440X(94)90215-1  0.623
1994 Loll PJ, Garavito RM. The isoforms of cyclooxygenase: Structure and function Expert Opinion On Investigational Drugs. 3: 1171-1180.  0.587
1980 Murthy MR, Garavito RM, Johnson JE, Rossmann MG. Structure of lobster apo-D-glyceraldehyde-3-phosphate dehydrogenase at 3.0 A resolution. Journal of Molecular Biology. 138: 859-72. PMID 7411626 DOI: 10.1016/0022-2836(80)90069-8  0.714
1978 Argos P, Garavito RM, Eventoff W, Rossmann MG, Brändén CI. Similarities in active center geometries of zinc-containing enzymes, proteases and dehydrogenases. Journal of Molecular Biology. 126: 141-58. PMID 105146 DOI: 10.1016/0022-2836(78)90356-X  0.52
1977 Garavito RM, Berger D, Rossmann MG. Molecular asymmetry in an abortive ternary complex of lobster glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 16: 4393-8. PMID 911762 DOI: 10.1021/Bi00639A010  0.46
1977 Garavito RM, Rossmann MG, Argos P, Eventoff W. Convergence of active center geometries. Biochemistry. 16: 5065-71. PMID 143959 DOI: 10.1021/Bi00642A019  0.542
1976 Olsen KW, Garavito RM, Sabesan MN, Rossmann MG. Anion binding sites in the active center of D-glyceraldehyde-3-phosphate dehydrogenase. Journal of Molecular Biology. 107: 571-6. PMID 1003476 DOI: 10.1016/S0022-2836(76)80083-6  0.684
1976 Olsen KW, Garavito RM, Sabesan MN, Rossmann MG. Studies on coenzyme binding to glyceraldehyde-3-phosphate dehydrogenase. Journal of Molecular Biology. 107: 577-84. PMID 187754 DOI: 10.1016/S0022-2836(76)80084-8  0.712
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