Karen Liby, Ph.D. - Publications

Affiliations: 
2002 University of Cincinnati, Cincinnati, OH 
Area:
Cell Biology, Oncology

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ball MS, Shipman EP, Kim H, Liby KT, Pioli PA. CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages. Plos One. 11: e0149600. PMID 26918785 DOI: 10.1371/journal.pone.0149600  0.48
2015 Cao M, Royce DB, Risingsong R, Williams CR, Sporn MB, Liby KT. The rexinoids LG100268 and LG101506 inhibit inflammation and suppress lung carcinogenesis in A/J mice. Cancer Prevention Research (Philadelphia, Pa.). PMID 26554632 DOI: 10.1158/1940-6207.CAPR-15-0325  0.48
2015 Cao M, Onyango EO, Williams CR, Royce DB, Gribble GW, Sporn MB, Liby KT. Novel Synthetic Pyridyl Analogues of CDDO-Imidazolide Are Useful New Tools in Cancer Prevention. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. PMID 26238177 DOI: 10.1016/j.phrs.2015.07.024  0.48
2015 To C, Ringelberg CS, Royce DB, Williams CR, Risingsong R, Sporn MB, Liby KT. Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis. Carcinogenesis. PMID 25939751 DOI: 10.1093/carcin/bgv061  0.48
2015 Canfield K, Li J, Wilkins OM, Morrison MM, Ung M, Wells W, Williams CR, Liby KT, Vullhorst D, Buonanno A, Hu H, Schiff R, Cook RS, Kurokawa M. Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells. Cell Cycle (Georgetown, Tex.). 14: 648-55. PMID 25590338 DOI: 10.4161/15384101.2014.994966  0.48
2014 To C, Sporn MB, Liby KT. PARP inhibitors for chemoprevention--reply. Cancer Prevention Research (Philadelphia, Pa.). 7: 1172. PMID 25368012 DOI: 10.1158/1940-6207.CAPR-14-0264  0.48
2014 So JY, Lin JJ, Wahler J, Liby KT, Sporn MB, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. Plos One. 9: e107616. PMID 25229616 DOI: 10.1371/journal.pone.0107616  0.48
2014 Fu L, Lin QX, Liby KT, Sporn MB, Gribble GW. An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives. Organic & Biomolecular Chemistry. 12: 5192-200. PMID 24915424 DOI: 10.1039/c4ob00679h  0.48
2014 To C, Kim EH, Royce DB, Williams CR, Collins RM, Risingsong R, Sporn MB, Liby KT. The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient mice. Cancer Prevention Research (Philadelphia, Pa.). 7: 698-707. PMID 24817481 DOI: 10.1158/1940-6207.CAPR-14-0047  0.48
2014 Fitzpatrick LR, Stonesifer E, Small JS, Liby KT. The synthetic triterpenoid (CDDO-Im) inhibits STAT3, as well as IL-17, and improves DSS-induced colitis in mice. Inflammopharmacology. 22: 341-9. PMID 24715223 DOI: 10.1007/s10787-014-0203-2  0.48
2014 Liby KT. Synthetic triterpenoids can protect against toxicity without reducing the efficacy of treatment with Carboplatin and Paclitaxel in experimental lung cancer. Dose-Response : a Publication of International Hormesis Society. 12: 136-51. PMID 24659938 DOI: 10.2203/dose-response.13-018.Liby  0.48
2014 Onyango EO, Fu L, Cao M, Liby KT, Sporn MB, Gribble GW. Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO) Bioorganic and Medicinal Chemistry Letters. 24: 532-534. PMID 24388806 DOI: 10.1016/j.bmcl.2013.12.034  0.48
2013 So JY, Wahler JE, Yoon T, Smolarek AK, Lin Y, Shih WJ, Maehr H, Uskokovic M, Liby KT, Sporn MB, Suh N. Oral administration of a gemini vitamin D analog, a synthetic triterpenoid and the combination prevents mammary tumorigenesis driven by ErbB2 overexpression. Cancer Prevention Research (Philadelphia, Pa.). 6: 959-70. PMID 23856074 DOI: 10.1158/1940-6207.CAPR-13-0087  0.48
2013 Sporn MB, Liby KT. Is lycopene an effective agent for preventing prostate cancer? Cancer Prevention Research (Philadelphia, Pa.). 6: 384-6. PMID 23483003 DOI: 10.1158/1940-6207.CAPR-13-0026  0.48
2013 Balboni AL, Hutchinson JA, DeCastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, DiRenzo J. ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Research. 73: 1020-30. PMID 23243027 DOI: 10.1158/0008-5472.CAN-12-2862  0.48
2013 Tran K, Risingsong R, Royce DB, Williams CR, Sporn MB, Pioli PA, Gediya LK, Njar VC, Liby KT. The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer. Carcinogenesis. 34: 199-210. PMID 23042302 DOI: 10.1093/carcin/bgs319  0.48
2013 Kaidery NA, Banerjee R, Yang L, Smirnova NA, Hushpulian DM, Liby KT, Williams CR, Yamamoto M, Kensler TW, Ratan RR, Sporn MB, Beal MF, Gazaryan IG, Thomas B. Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease. Antioxidants & Redox Signaling. 18: 139-57. PMID 22746536 DOI: 10.1089/ars.2011.4491  0.48
2013 Sporn MB, Liby KT. A mini-review of chemoprevention of cancer - past, present, and future Progress in Chemistry. 25: 1421-1428.  0.48
2012 Liby KT, Sporn MB. Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease. Pharmacological Reviews. 64: 972-1003. PMID 22966038 DOI: 10.1124/pr.111.004846  0.48
2012 Sporn MB, Liby KT. NRF2 and cancer: the good, the bad and the importance of context. Nature Reviews. Cancer. 12: 564-71. PMID 22810811 DOI: 10.1038/nrc3278  0.48
2012 Tran K, Risingsong R, Royce D, Williams CR, Sporn MB, Liby K. The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice. Cancer Prevention Research (Philadelphia, Pa.). 5: 726-34. PMID 22401982 DOI: 10.1158/1940-6207.CAPR-11-0404  0.48
2012 Kim EH, Deng C, Sporn MB, Royce DB, Risingsong R, Williams CR, Liby KT. CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice. Cancer Prevention Research (Philadelphia, Pa.). 5: 89-97. PMID 21933912 DOI: 10.1158/1940-6207.CAPR-11-0359  0.48
2011 Pareek TK, Belkadi A, Kesavapany S, Zaremba A, Loh SL, Bai L, Cohen ML, Meyer C, Liby KT, Miller RH, Sporn MB, Letterio JJ. Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis. Scientific Reports. 1: 201. PMID 22355716 DOI: 10.1038/srep00201  0.48
2011 Yore MM, Kettenbach AN, Sporn MB, Gerber SA, Liby KT. Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR. Plos One. 6: e22862. PMID 21818401 DOI: 10.1371/journal.pone.0022862  0.48
2011 Neymotin A, Calingasan NY, Wille E, Naseri N, Petri S, Damiano M, Liby KT, Risingsong R, Sporn M, Beal MF, Kiaei M. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 51: 88-96. PMID 21457778 DOI: 10.1016/j.freeradbiomed.2011.03.027  0.48
2011 Kim EH, Deng CX, Sporn MB, Liby KT. CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 425-34. PMID 21372041 DOI: 10.1158/1940-6207.CAPR-10-0153  0.48
2011 Sporn MB, Liby KT, Yore MM, Fu L, Lopchuk JM, Gribble GW. New synthetic triterpenoids: Potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress Journal of Natural Products. 74: 537-545. PMID 21309592 DOI: 10.1021/np100826q  0.48
2011 Townson JL, Macdonald IC, Liby KT, Mackenzie L, Dales DW, Hedley BD, Foster PJ, Sporn MB, Chambers AF. The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis. Clinical & Experimental Metastasis. 28: 309-17. PMID 21234655 DOI: 10.1007/s10585-011-9374-z  0.48
2010 Liby KT, Royce DB, Risingsong R, Williams CR, Maitra A, Hruban RH, Sporn MB. Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer. Cancer Prevention Research (Philadelphia, Pa.). 3: 1427-34. PMID 20959520 DOI: 10.1158/1940-6207.CAPR-10-0197  0.48
2010 Stack C, Ho D, Wille E, Calingasan NY, Williams C, Liby K, Sporn M, Dumont M, Beal MF. Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease. Free Radical Biology & Medicine. 49: 147-58. PMID 20338236 DOI: 10.1016/j.freeradbiomed.2010.03.017  0.48
2010 Nagaraj S, Youn JI, Weber H, Iclozan C, Lu L, Cotter MJ, Meyer C, Becerra CR, Fishman M, Antonia S, Sporn MB, Liby KT, Rawal B, Lee JH, Gabrilovich DI. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1812-23. PMID 20215551 DOI: 10.1158/1078-0432.CCR-09-3272  0.48
2010 Honda T, Padegimas EM, David E, Sundararajan C, Liby KT, Williams C, Sporn MB, Visnick M. 2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride. A novel and highly potent anti-inflammatory and cytoprotective agent. Bioorganic & Medicinal Chemistry Letters. 20: 2275-8. PMID 20188548 DOI: 10.1016/j.bmcl.2010.02.007  0.48
2009 Liby K, Risingsong R, Royce DB, Williams CR, Ma T, Yore MM, Sporn MB. Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. Cancer Prevention Research (Philadelphia, Pa.). 2: 1050-8. PMID 19952361 DOI: 10.1158/1940-6207.CAPR-09-0085  0.48
2009 Shin S, Wakabayashi J, Yates MS, Wakabayashi N, Dolan PM, Aja S, Liby KT, Sporn MB, Yamamoto M, Kensler TW. Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide. European Journal of Pharmacology. 620: 138-44. PMID 19698707 DOI: 10.1016/j.ejphar.2009.08.022  0.48
2009 Reddy NM, Suryanaraya V, Yates MS, Kleeberger SR, Hassoun PM, Yamamoto M, Liby KT, Sporn MB, Kensler TW, Reddy SP. The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 180: 867-74. PMID 19679692 DOI: 10.1164/rccm.200905-0670OC  0.48
2009 Pitha-Rowe I, Liby K, Royce D, Sporn M. Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3K/AKT signaling through inhibition of the lipid phosphatase PTEN. Investigative Ophthalmology & Visual Science. 50: 5339-47. PMID 19494206 DOI: 10.1167/iovs.09-3648  0.48
2009 Yang L, Calingasan NY, Thomas B, Chaturvedi RK, Kiaei M, Wille EJ, Liby KT, Williams C, Royce D, Risingsong R, Musiek ES, Morrow JD, Sporn M, Beal MF. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. Plos One. 4: e5757. PMID 19484125 DOI: 10.1371/journal.pone.0005757  0.48
2009 Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW. Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice. Carcinogenesis. 30: 1024-31. PMID 19386581 DOI: 10.1093/carcin/bgp100  0.48
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Flint Beal M, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease. Journal of Neurochemistry. 109: 502-12. PMID 19200343 DOI: 10.1111/j.1471-4159.2009.05970.x  0.48
2009 Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 250-5. PMID 19104057 DOI: 10.1073/pnas.0804333106  0.48
2009 Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Beal MF, Lin MT. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease: (Journal of Neurochemistry (2009) 109 (502-512)) Journal of Neurochemistry. 109: 1192. DOI: 10.1111/j.1471-4159.2009.06053.x  0.48
2008 Liby K, Yore MM, Roebuck BD, Baumgartner KJ, Honda T, Sundararajan C, Yoshizawa H, Gribble GW, Williams CR, Risingsong R, Royce DB, Dinkova-Kostova AT, Stephenson KK, Egner PA, Yates MS, et al. A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin Cancer Research. 68: 6727-6733. PMID 18701497 DOI: 10.1158/0008-5472.CAN-08-1123  0.48
2008 Liby K, Risingsong R, Royce DB, R. Williams C, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB. Prevention and treatment of experimental estrogen receptor- negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl ester and the rexinoid LG100268 Clinical Cancer Research. 14: 4556-4563. PMID 18628471 DOI: 10.1158/1078-0432.CCR-08-0040  0.48
2008 Liby K, Black CC, Royce DB, Williams CR, Risingsong R, Yore MM, Liu X, Honda T, Gribble GW, Lamph WW, Sporn TA, Dmitrovsky E, Sporn MB. The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis Molecular Cancer Therapeutics. 7: 1251-1257. PMID 18483313 DOI: 10.1158/1535-7163.MCT-08-0023  0.48
2008 Osburn WO, Yates MS, Dolan PD, Chen S, Liby KT, Sporn MB, Taguchi K, Yamamoto M, Kensler TW. Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 104: 218-27. PMID 18417483 DOI: 10.1093/toxsci/kfn079  0.48
2008 Alabran JL, Cheuk A, Liby K, Sporn M, Khan J, Letterio J, Leskov KS. Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO. Cancer Biology & Therapy. 7: 709-17. PMID 18277094 DOI: 10.4161/cbt.7.5.5713  0.48
2008 Dinkova-Kostova AT, Jenkins SN, Wehage SL, Huso DL, Benedict AL, Stephenson KK, Fahey JW, Liu H, Liby KT, Honda T, Gribble GW, Sporn MB, Talalay P. A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice Biochemical and Biophysical Research Communications. 367: 859-865. PMID 18206646 DOI: 10.1016/j.bbrc.2008.01.026  0.48
2007 Liby K, Royce DB, Risingsong R, Williams CR, Wood MD, Chandraratna RA, Sporn MB. A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6237-43. PMID 17947492 DOI: 10.1158/1078-0432.CCR-07-1342  0.48
2007 Thimmulappa RK, Fuchs RJ, Malhotra D, Scollick C, Traore K, Bream JH, Trush MA, Liby KT, Sporn MB, Kensler TW, Biswal S. Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils. Antioxidants & Redox Signaling. 9: 1963-70. PMID 17822364 DOI: 10.1089/ars.2007.1745  0.48
2007 Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB. Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities Molecular Cancer Therapeutics. 6: 2113-2119. PMID 17620440 DOI: 10.1158/1535-7163.MCT-07-0180  0.48
2007 Liby KT, Yore MM, Sporn MB. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nature Reviews. Cancer. 7: 357-69. PMID 17446857 DOI: 10.1038/nrc2129  0.48
2007 Honda T, Sundararajan C, Yoshizawa H, Su X, Honda Y, Liby KT, Sporn MB, Gribble GW. Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: Highly potent anti-inflammatory and cytoprotective agents Journal of Medicinal Chemistry. 50: 1731-1734. PMID 17367124 DOI: 10.1021/jm070141c  0.48
2007 Liby K, Royce DB, Williams CR, Risingsong R, Yore MM, Honda T, Gribble GW, Dmitrovsky E, Sporn TA, Sporn MB. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice Cancer Research. 67: 2414-2419. PMID 17363558 DOI: 10.1158/0008-5472.CAN-06-4534  0.48
2007 Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW. Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Molecular Cancer Therapeutics. 6: 154-62. PMID 17237276 DOI: 10.1158/1535-7163.MCT-06-0516  0.48
2007 Hock TD, Liby K, Wright MM, McConnell S, Schorpp-Kistner M, Ryan TM, Agarwal A. JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells. The Journal of Biological Chemistry. 282: 6875-86. PMID 17204476 DOI: 10.1074/jbc.M608456200  0.48
2007 Sporn MB, Liby K, Yore MM, Suh N, Albini A, Honda T, Sundararajan C, Gribble GW. Platforms and networks in triterpenoid pharmacology Drug Development Research. 68: 174-182. DOI: 10.1002/ddr.20179  0.48
2006 Yore MM, Liby KT, Honda T, Gribble GW, Sporn MB. The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta. Molecular Cancer Therapeutics. 5: 3232-9. PMID 17148759 DOI: 10.1158/1535-7163.MCT-06-0444  0.48
2006 Thimmulappa RK, Scollick C, Traore K, Yates M, Trush MA, Liby KT, Sporn MB, Yamamoto M, Kensler TW, Biswal S. Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide. Biochemical and Biophysical Research Communications. 351: 883-9. PMID 17097057 DOI: 10.1016/j.bbrc.2006.10.102  0.48
2006 Liby K, Rendi M, Suh N, Royce DB, Risingsong R, Williams CR, Lamph W, Labrie F, Krajewski S, Xu X, Kim H, Brown P, Sporn MB. The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5902-9. PMID 17020999 DOI: 10.1158/1078-0432.CCR-06-1119  0.48
2006 Honda T, Liby KT, Su X, Sundararajan C, Honda Y, Suh N, Risingsong R, Williams CR, Royce DB, Sporn MB, Gribble GW. Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A. Bioorganic & Medicinal Chemistry Letters. 16: 6306-9. PMID 16996735 DOI: 10.1016/j.bmcl.2006.09.012  0.48
2006 Liby K, Voong N, Williams CR, Risingsong R, Royce DB, Honda T, Gribble GW, Sporn MB, Letterio JJ. The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4288-93. PMID 16857804 DOI: 10.1158/1078-0432.CCR-06-0215  0.48
2006 Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M, Suh N. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells. Molecular Cancer Therapeutics. 5: 1452-8. PMID 16818503 DOI: 10.1158/1535-7163.MCT-06-0136  0.48
2006 Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole. Cancer Research. 66: 2488-94. PMID 16489057 DOI: 10.1158/0008-5472.CAN-05-3823  0.48
2006 Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts Cancer Letters. 240: 243-252. PMID 16271437 DOI: 10.1016/j.canlet.2005.09.012  0.48
2005 Sporn MB, Liby KT. Cancer chemoprevention: scientific promise, clinical uncertainty. Nature Clinical Practice. Oncology. 2: 518-25. PMID 16205771 DOI: 10.1038/ncponc0319  0.48
2005 Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Research. 65: 4789-98. PMID 15930299 DOI: 10.1158/0008-5472.CAN-04-4539  0.48
2005 Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress Proceedings of the National Academy of Sciences of the United States of America. 102: 4584-4589. PMID 15767573 DOI: 10.1073/pnas.0500815102  0.48
2004 Honda T, Janosik T, Honda Y, Han J, Liby KT, Williams CR, Couch RD, Anderson AC, Sporn MB, Gribble GW. Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets. Journal of Medicinal Chemistry. 47: 4923-32. PMID 15369396 DOI: 10.1021/jm049727e  0.48
2004 Rendi MH, Suh N, Lamph WW, Krajewski S, Reed JC, Heyman RA, Berchuck A, Liby K, Risingsong R, Royce DB, Williams CR, Sporn MB. The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer. Cancer Research. 64: 3566-71. PMID 15150113 DOI: 10.1158/0008-5472.CAN-04-0234  0.48
2003 Liby K, Neltner B, Mohamet L, Menchen L, Ben-Jonathan N. Prolactin overexpression by MDA-MB-435 human breast cancer cells accelerates tumor growth. Breast Cancer Research and Treatment. 79: 241-52. PMID 12825859 DOI: 10.1023/A:1023956223037  0.48
2003 Liby K, Neltner B, Mohamet L, Burd C, Ben-Jonathan N. Endostatin expression by MDA-MB-435 breast cancer cells effectively inhibits tumor growth. Cancer Biology & Therapy. 2: 48-52. PMID 12673115  0.48
2002 Ben-Jonathan N, Liby K, McFarland M, Zinger M. Prolactin as an autocrine/paracrine growth factor in human cancer. Trends in Endocrinology and Metabolism: Tem. 13: 245-50. PMID 12128285 DOI: 10.1016/S1043-2760(02)00603-3  0.48
2001 Liby K, Wu H, Ouyang B, Wu S, Chen J, Dai W. Identification of the human homologue of the early-growth response gene Snk, encoding a serum-inducible kinase Mitochondrial Dna. 11: 527-533. PMID 11696980 DOI: 10.3109/10425170109041337  0.48
1999 Khurana S, Liby K, Buckley AR, Ben-Jonathan N. Proteolysis of Human Prolactin: Resistance to Cathepsin D and Formation of a Nonangiostatic, C-Terminal 16K Fragment by Thrombin1. Endocrinology. 140: 4127-4132. PMID 28200812 DOI: 10.1210/endo.140.9.6955  0.48
1999 Khurana S, Liby K, Buckley AR, Ben-Jonathan N. Proteolysis of human prolactin: resistance to cathepsin D and formation of a nonangiostatic, C-terminal 16K fragment by thrombin. Endocrinology. 140: 4127-32. PMID 10465285 DOI: 10.1210/endo.140.9.6955  0.48
Show low-probability matches.