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Donald D. Muccio - Publications

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Biochemistry, Microbiology Biology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Williams AP, Waters AM, Stewart JE, Atigadda VR, Mroczek-Musulman E, Muccio DD, Grubbs CJ, Beierle EA. A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro. The Journal of Surgical Research. 228: 54-62. PMID 29907230 DOI: 10.1016/J.Jss.2018.02.057  0.375
2018 Chou CF, Hsieh YH, Grubbs CJ, Atigadda VR, Mobley JA, Dummer R, Muccio DD, Eto I, Elmets CA, Garvey WT, Chang PL. The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis. Journal of Dermatological Science. PMID 29599065 DOI: 10.1016/J.Jdermsci.2018.03.006  0.323
2016 Muccio DD, Atigadda VR, Brouillette WJ, Bland KI, Krontiras H, Grubbs CJ. Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention. Current Topics in Medicinal Chemistry. PMID 27320329 DOI: 10.2174/1568026616666160617093604  0.337
2016 Wu L, Chaudhary SC, Atigadda VR, Belyaeva OV, Harville SR, Elmets CA, Muccio DD, Athar M, Kedishvili NY. Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis. Plos One. 11: e0153556. PMID 27078158 DOI: 10.1371/Journal.Pone.0153556  0.323
2015 Atigadda VR, Xia G, Deshpande A, Wu L, Kedishvili N, Smith CD, Krontiras H, Bland KI, Grubbs CJ, Brouillette WJ, Muccio DD. Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. Journal of Medicinal Chemistry. 58: 7763-74. PMID 26331194 DOI: 10.1021/Acs.Jmedchem.5B00829  0.632
2015 Waters AM, Stewart JE, Atigadda VR, Mroczek-Musulman E, Muccio DD, Grubbs CJ, Beierle EA. Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma. Molecular Cancer Therapeutics. PMID 25944918 DOI: 10.1158/1535-7163.Mct-14-1103  0.308
2014 Atigadda VR, Xia G, Desphande A, Boerma LJ, Lobo-Ruppert S, Grubbs CJ, Smith CD, Brouillette WJ, Muccio DD. Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity. Journal of Medicinal Chemistry. 57: 5370-80. PMID 24801499 DOI: 10.1021/Jm5004792  0.608
2014 Desphande A, Xia G, Boerma LJ, Vines KK, Atigadda VR, Lobo-Ruppert S, Grubbs CJ, Moeinpour FL, Smith CD, Christov K, Brouillette WJ, Muccio DD. Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention. Bioorganic & Medicinal Chemistry. 22: 178-85. PMID 24359708 DOI: 10.1016/J.Bmc.2013.11.039  0.734
2014 Boerma LJ, Xia G, Qui C, Cox BD, Chalmers MJ, Smith CD, Lobo-Ruppert S, Griffin PR, Muccio DD, Renfrow MB. Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain. The Journal of Biological Chemistry. 289: 814-26. PMID 24187139 DOI: 10.1074/Jbc.M113.476861  0.704
2013 Cox BD, Muccio DD, Hamilton TP. Conformational Analysis of Retinoic Acids: Effects of Steric Interactions on Nonplanar Conjugated Polyenes. Computational & Theoretical Chemistry. 1011: 11-20. PMID 25798372 DOI: 10.1016/J.Comptc.2013.01.013  0.597
2013 Vedell PT, Lu Y, Grubbs CJ, Yin Y, Jiang H, Bland KI, Muccio DD, Cvetkovic D, You M, Lubet R. Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene). Molecular Pharmacology. 83: 698-708. PMID 23292798 DOI: 10.1124/Mol.112.082404  0.355
2012 Whitworth JM, Straughn JM, Atigadda VR, Muccio DD, Buchsbaum DJ. The use of retinoids in ovarian cancer: a review of the literature. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 22: 191-8. PMID 22146768 DOI: 10.1097/Igc.0B013E318236A2Ec  0.321
2011 Jackson PL, Noerager BD, Jablonsky MJ, Hardison MT, Cox BD, Patterson JC, Dhanapal B, Blalock JE, Muccio DD. A CXCL8 receptor antagonist based on the structure of N-acetyl-proline-glycine-proline. European Journal of Pharmacology. 668: 435-42. PMID 21458447 DOI: 10.1016/J.Ejphar.2011.02.045  0.622
2011 Xia G, Boerma LJ, Cox BD, Qiu C, Kang S, Smith CD, Renfrow MB, Muccio DD. Structure, energetics, and dynamics of binding coactivator peptide to the human retinoid X receptor α ligand binding domain complex with 9-cis-retinoic acid. Biochemistry. 50: 93-105. PMID 21049972 DOI: 10.1021/Bi101288Y  0.708
2011 Cabrera MC, Diaz-Cruz ES, Pishvaian MJ, Muccio D, Grubbs C, Furth P. Abstract A20: Investigating the role of cell cycle proteins and CDK4/6 inhibitor PD0332991 in the redifferentiation of irreversible dysplasia Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A20  0.304
2011 Verney ZM, Atigadda VR, Elmets CA, Muccio DD, Grubbs CJ. Abstract A20: Differential rates of proliferation and apoptosis observed in human cutaneous T-cell lymphoma cell lines, in response to treatment with 9-cis UAB30, a novel rexinoid analog Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A20  0.306
2011 Whitworth JM, Oliver PJ, Muccio DD, Straughn JM, Buchsbaum DJ. Abstract 181: The combination of a novel retinoid compound with standard chemotherapy increases cytotoxicity in an ovarian cancer cell line Cancer Research. 71: 181-181. DOI: 10.1158/1538-7445.Am2011-181  0.358
2010 Cvetkovic D, Clapper M, Wang Y, You M, Muccio D, Grubbs C, Lubet R. Abstract 1244: RXR agonist induced changes in gene expression in liver and mammary cancers: Confirmation by RT-PCR on independent samples collected years apart Cancer Research. 70: 1244-1244. DOI: 10.1158/1538-7445.Am10-1244  0.335
2009 Muccio D, Lubet R, Atigadda V, Brouillette W, Grubbs C. Effects of methyl derivatives of the rexinoid UAB30 on methylnitrosourea (MNU) induced mammary cancers and on various indicators of toxicity. Cancer Research. 69: 1108. DOI: 10.1158/0008-5472.Sabcs-1108  0.402
2008 Love WK, Deangelis JT, Berletch JB, Phipps SM, Andrews LG, Brouillette WJ, Muccio DD, Tollefsbol TO. The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells. Translational Oncology. 1: 148-52. PMID 18795149 DOI: 10.1593/Tlo.08142  0.304
2007 Lee YC, Jackson PL, Jablonsky MJ, Muccio DD. Conformation of 3'CMP bound to RNase A using TrNOESY. Archives of Biochemistry and Biophysics. 463: 37-46. PMID 17416340 DOI: 10.1016/J.Abb.2007.02.034  0.541
2006 Grubbs CJ, Lubet RA, Atigadda VR, Christov K, Deshpande AM, Tirmal V, Xia G, Bland KI, Eto I, Brouillette WJ, Muccio DD. Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers. Carcinogenesis. 27: 1232-9. PMID 16344269 DOI: 10.1093/Carcin/Bgi308  0.612
2004 Pal B, Pybus B, Muccio DD, Chattopadhyay D. Biochemical characterization and crystallization of recombinant 3-phosphoglycerate kinase of Plasmodium falciparum. Biochimica Et Biophysica Acta. 1699: 277-80. PMID 15158737 DOI: 10.1016/J.Bbapap.2004.01.003  0.647
2003 Grubbs CJ, Hill DL, Bland KI, Beenken SW, Lin TH, Eto I, Atigadda VR, Vines KK, Brouillette WJ, Muccio DD. 9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers. Cancer Letters. 201: 17-24. PMID 14580682 DOI: 10.1016/S0304-3835(03)00461-0  0.714
2003 Atigadda VR, Vines KK, Grubbs CJ, Hill DL, Beenken SL, Bland KI, Brouillette WJ, Muccio DD. Conformationally defined retinoic acid analogues. 5. Large-scale synthesis and mammary cancer chemopreventive activity for (2E,4E,6Z,8E)-8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid (9cUAB30). Journal of Medicinal Chemistry. 46: 3766-9. PMID 12904083 DOI: 10.1021/Jm030095Q  0.74
2001 Devedjiev Y, Symersky J, Singh R, Jedrzejas M, Brouillette C, Brouillette W, Muccio D, Chattopadhyay D, DeLucas L. Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis. Acta Crystallographica. Section D, Biological Crystallography. 57: 806-12. PMID 11375500 DOI: 10.1107/S0907444901003523  0.315
2001 Lee YC, Jackson PL, Jablonsky MJ, Muccio DD, Pfister RR, Haddox JL, Sommers CI, Anantharamaiah GM, Chaddha M. NMR conformational analysis of cis and trans proline isomers in the neutrophil chemoattractant, N-acetyl-proline-glycine-proline. Biopolymers. 58: 548-61. PMID 11246204 DOI: 10.1002/1097-0282(200105)58:6<548::Aid-Bip1030>3.0.Co;2-B  0.519
2001 Ponder MS, Alan Long J, Williams LM, Hamilton TP, Muccio DD. Structural studies on conformationally defined 6-s-trans UAB retinoids Journal of Molecular Structure: Theochem. 549: 39-45. DOI: 10.1016/S0166-1280(01)00490-0  0.356
2000 Wierzbicki A, Knight CA, Rutland TJ, Muccio DD, Pybus BS, Sikes CS. Structure-function relationship in the antifreeze activity of synthetic alanine-lysine antifreeze polypeptides. Biomacromolecules. 1: 268-74. PMID 11710110 DOI: 10.1021/Bm000004W  0.664
1998 Muccio DD, Brouillette WJ, Breitman TR, Taimi M, Emanuel PD, Zhang X, Chen G, Sani BP, Venepally P, Reddy L, Alam M, Simpson-Herren L, Hill DL. Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias. Journal of Medicinal Chemistry. 41: 1679-87. PMID 9572893 DOI: 10.1021/Jm970635H  0.371
1997 Shimada T, Ross AC, Muccio DD, Brouillette WJ, Shealy YF. Regulation of hepatic lecithin:retinol acyltransferase activity by retinoic acid receptor-selective retinoids Archives of Biochemistry and Biophysics. 344: 220-227. PMID 9244401 DOI: 10.1006/Abbi.1997.0209  0.326
1997 Lake CH, Alam M, Muccio DD, Brouillette WJ. A structural model for a new class of conformationally constrained retinoid: (2Z,4E)-4-[3′,4′-dihydro-1′(2′H)-naphthalene-1′-ylidene]-2-butenoic acid Journal of Chemical Crystallography. 27: 231-235. DOI: 10.1007/Bf02575960  0.332
1996 Muccio DD, Brouillette WJ, Alam M, Vaezi MF, Sani BP, Venepally P, Reddy L, Li E, Norris AW, Simpson-Herren L, Hill DL. Conformationally defined 6-s-trans-retinoic acid analogs. 3. Structure-activity relationships for nuclear receptor binding, transcriptional activity, and cancer chemopreventive activity. Journal of Medicinal Chemistry. 39: 3625-35. PMID 8809153 DOI: 10.1021/Jm9603126  0.35
1995 Robinson CY, Waterhous DV, Muccio DD, Brouillette WJ. Conformationally constrained precursors to retinoic acid analogs which stabilize the 9Z-configuration Bioorganic and Medicinal Chemistry Letters. 5: 953-958. DOI: 10.1016/0960-894X(95)00151-I  0.348
1995 Vaezi MF, Brouillette WJ, Muccio DD. 13C NMR assignments of conforma-tionally defined 6-s-trans-retinoids Magnetic Resonance in Chemistry. 33: 497-499. DOI: 10.1002/Mrc.1260330616  0.343
1994 Vaezi MF, Alam M, Sani BP, Rogers TS, Simpson-Herren L, Wille JJ, Hill DL, Doran TI, Brouillette WJ, Muccio DD. A conformationally defined 6-s-trans-retinoic acid isomer: synthesis, chemopreventive activity, and toxicity. Journal of Medicinal Chemistry. 37: 4499-507. PMID 7799400 DOI: 10.1021/Jm00052A009  0.393
1990 Waterhous DV, Muccio DD. 1H and13C NMR studies on the self-association of retinoic acid Magnetic Resonance in Chemistry. 28: 223-226. DOI: 10.1002/Mrc.1260280306  0.317
1987 Hope KD, Robinson CY, Vaezi MF, Brouillette WJ, Muccio DD. 13C NMR assignments of the isoprenoid chain carbons of retinoids from empirical chemical shift differences Magnetic Resonance in Chemistry. 25: 1040-1045. DOI: 10.1002/Mrc.1260251204  0.32
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