Gary W. Reuther - Publications

Biology (Cell Biology, Microbiology, Molecular Biology) University of South Florida, Tampa, FL, United States 
Molecular Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mazzacurati L, Collins RJ, Pandey G, Lambert-Showers QT, Amin NE, Zhang L, Stubbs MC, Epling-Burnette PK, Koblish HK, Reuther GW. The pan-PIM inhibitor INCB053914 displays potent synergy in combination with ruxolitinib in models of MPN. Blood Advances. 3: 3503-3514. PMID 31725895 DOI: 10.1182/bloodadvances.2019000260  0.36
2018 Koblish H, Li YL, Shin N, Hall L, Wang Q, Wang K, Covington M, Marando C, Bowman K, Boer J, Burke K, Wynn R, Margulis A, Reuther GW, Lambert QT, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. Plos One. 13: e0199108. PMID 29927999 DOI: 10.1371/journal.pone.0199108  0.76
2017 Ember SW, Lambert QT, Berndt N, Gunawan S, Ayaz M, Tauro M, Zhu JY, Cranfill PJ, Greninger P, Lynch CC, Benes CH, Lawrence HR, Reuther GW, Lawrence NJ, Schonbrunn E. Potent dual BET bromodomain-kinase inhibitors as value added multi-targeted chemical probes and cancer therapeutics. Molecular Cancer Therapeutics. PMID 28336808 DOI: 10.1158/1535-7163.MCT-16-0568-T  0.76
2016 Basiorka AA, McGraw KL, De Ceuninck L, Griner LN, Zhang L, Clark JA, Caceres G, Sokol L, Komrokji RS, Reuther GW, Wei S, Tavernier J, List AF. Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41. Cancer Research. PMID 27197154 DOI: 10.1158/0008-5472.CAN-15-1756  0.64
2015 Mazzacurati L, Lambert QT, Pradhan A, Griner LN, Huszar D, Reuther GW. The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells. Oncotarget. PMID 26472029 DOI: 10.18632/oncotarget.5653  0.48
2013 Griner LN, McGraw KL, Johnson JO, List AF, Reuther GW. JAK2-V617F-mediated signalling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth. British Journal of Haematology. 160: 177-87. PMID 23157224 DOI: 10.1111/bjh.12103  0.48
2012 Roll JD, Reuther GW. ALK-activating homologous mutations in LTK induce cellular transformation. Plos One. 7: e31733. PMID 22347506 DOI: 10.1371/journal.pone.0031733  0.48
2011 Lambert QT, Pradhan A, Roll JD, Reuther GW. Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activity. The Biochemical Journal. 438: 155-64. PMID 21631431 DOI: 10.1042/BJ20110351  0.48
2010 Griner LN, Reuther GW. Aggressive myeloid leukemia formation is directed by the Musashi 2/Numb pathway. Cancer Biology & Therapy. 10: 979-82. PMID 21084860  0.64
2010 Gordon GM, Lambert QT, Daniel KG, Reuther GW. Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-γ. The Biochemical Journal. 432: 255-65. PMID 20868368 DOI: 10.1042/BJ20100774  0.48
2010 Roll JD, Reuther GW. CRLF2 and JAK2 in B-progenitor acute lymphoblastic leukemia: a novel association in oncogenesis. Cancer Research. 70: 7347-52. PMID 20807819 DOI: 10.1158/0008-5472.CAN-10-1528  0.48
2010 Majumder A, Govindasamy L, Magis A, Kiss R, Polgár T, Baskin R, Allan RW, Agbandje-McKenna M, Reuther GW, Keseru GM, Bisht KS, Sayeski PP. Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core. The Journal of Biological Chemistry. 285: 31399-407. PMID 20667821 DOI: 10.1074/jbc.M110.168211  0.48
2010 Rao R, Nalluri S, Fiskus W, Balusu R, Joshi A, Mudunuru U, Buckley KM, Robbins K, Ustun C, Reuther GW, Bhalla KN. Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells. Molecular Cancer Therapeutics. 9: 2232-42. PMID 20663926 DOI: 10.1158/1535-7163.MCT-10-0336  0.48
2010 Pradhan A, Lambert QT, Griner LN, Reuther GW. Activation of JAK2-V617F by components of heterodimeric cytokine receptors. The Journal of Biological Chemistry. 285: 16651-63. PMID 20363735 DOI: 10.1074/jbc.M109.071191  0.76
2008 Cha JY, Lambert QT, Reuther GW, Der CJ. Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis. Molecular Cancer Research : McR. 6: 435-45. PMID 18337450 DOI: 10.1158/1541-7786.MCR-07-0187  0.48
2008 Gilkes DM, Pan Y, Coppola D, Yeatman T, Reuther GW, Chen J. Regulation of MDMX expression by mitogenic signaling. Molecular and Cellular Biology. 28: 1999-2010. PMID 18172009 DOI: 10.1128/MCB.01633-07  0.48
2007 Pradhan A, Lambert QT, Reuther GW. Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 18502-7. PMID 18003935 DOI: 10.1073/pnas.0702388104  0.76
2006 Lambert QT, Reuther GW. Activation of Ras proteins by Ras guanine nucleotide releasing protein family members. Methods in Enzymology. 407: 82-98. PMID 16757316 DOI: 10.1016/S0076-6879(05)07008-4  0.76
2002 Lambert JM, Lambert QT, Reuther GW, Malliri A, Siderovski DP, Sondek J, Collard JG, Der CJ. Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. Nature Cell Biology. 4: 621-5. PMID 12134164 DOI: 10.1038/ncb833  0.48
2002 Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ. RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. The Journal of Biological Chemistry. 277: 30508-14. PMID 11880369 DOI: 10.1074/jbc.M111330200  0.48
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